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https://www.readbyqxmd.com/read/29345602/the-mental-health-of-adolescents-and-pre-adolescents-living-with-inherited-arrhythmia-syndromes-a-systematic-review-of-the-literature
#1
Patricia E Longmuir, Margaret Sampson, Jennifer Ham, Makenzie Weekes, Bhavika J Patel, Robert M Gow
Potentially fatal arrhythmias add to the mental health challenges of adolescence. This systematic review sought to summarise current knowledge regarding the mental health of adolescents and pre-adolescents diagnosed with inherited arrhythmia syndromes. Searches combining psychological problems with inherited cardiac arrhythmia diagnoses identified 16 studies with paediatric (<18 years) inherited arrhythmia patients. All studies were cross-sectional; 8/16 required an implantable cardioverter defibrillator...
January 18, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29341497/defining-behavioral-components-of-social-functioning-in-adults-with-autism-spectrum-disorder-as-targets-for-treatment
#2
Ashley A Pallathra, Monica E Calkins, Julia Parish-Morris, Brenna B Maddox, Leat S Perez, Judith Miller, Ruben C Gur, David S Mandell, Robert T Schultz, Edward S Brodkin
There is increasing recognition that adults with autism spectrum disorder (ASD) would benefit from treatment to improve social functioning, a key factor in adults' overall quality of life. However, the various behavioral components of social functioning (i.e., categories of behaviors underlying social functioning), including social motivation, social anxiety, social cognition, and social skills, have not all been assessed together in any sample of adults with ASD, making it difficult to know the relative levels of impairment in these various categories, the relationships among these categories, or promising targets for treatments...
January 17, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29338470/measurement-error-in-the-liebowitz-social-anxiety-scale-results-from-a-general-adult-population-in-japan
#3
Koki Takada, Kana Takahashi, Kazuki Hirao
OBJECTIVE: Although the self-report version of Liebowitz Social Anxiety Scale (LSAS) is frequently used to measure social anxiety, data is lacking on the smallest detectable change (SDC), an important index of measurement error. We therefore aimed to determine the SDC of LSAS. METHODS: Japanese adults aged 20-69 years were invited from a panel managed by a nationwide internet research agency. We then conducted a test-retest internet survey with a two-week interval to estimate the SDC at the individual (SDCind) and group (SDCgroup) levels...
January 17, 2018: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/29337904/maternal-exposure-to-pm2-5-during-pregnancy-induces-impaired-development-of-cerebral-cortex-in-mice-offspring
#4
Tianliang Zhang, Xinrui Zheng, Xia Wang, Hui Zhao, Tingting Wang, Hongxia Zhang, Wanwei Li, Hua Shen, Li Yu
Air pollution is a serious environmental health problem closely related to the occurrence of central nervous system diseases. Exposure to particulate matter with an aerodynamic diameter less than or equal to 2.5 µm (PM2.5) during pregnancy may affect the growth and development of infants. The present study was to investigate the effects of maternal exposure to PM2.5 during pregnancy on brain development in mice offspring. Pregnant mice were randomly divided into experimental groups of low-, medium-, or high-dosages of PM2...
January 16, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29337001/antidepressant-treatment-duration-in-pediatric-depressive-and-anxiety-disorders-how-long-is-long-enough
#5
Elizabeth E Hathaway, John T Walkup, Jeffrey R Strawn
Anxiety and depressive disorders are common in the pediatric primary care setting, and respond to both psychotherapeutic and psychopharmacologic treatment. However, there are limited data regarding the optimal treatment duration. This article systematically reviews guidelines and clinical trial data related to antidepressant treatment duration in pediatric patients with depressive and anxiety disorders. The extant literature suggests 9-12 months of antidepressant treatment for youth with major depressive disorder...
January 11, 2018: Current Problems in Pediatric and Adolescent Health Care
https://www.readbyqxmd.com/read/29336041/symptoms-of-social-anxiety-depression-and-stress-in-parents-of-children-with-social-anxiety-disorder
#6
Brynjar Halldorsson, Jenny Draisey, Peter Cooper, Cathy Creswell
OBJECTIVES: It has been suggested that elevated maternal social anxiety may play a disorder-specific role in maintaining childhood social anxiety disorder (SAD), but few studies have examined whether mothers of children with SAD are more socially anxious than mothers of children with other anxiety disorders (ANX). This study set out to examine whether symptoms of social anxiety were more severe amongst mothers of 7-12 year old children presenting for treatment with SAD (n = 260) compared to those presenting with ANX (n = 138)...
January 16, 2018: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/29336012/predictors-and-consequences-of-health-anxiety-symptoms-a-novel-twin-modeling-study
#7
C López-Solà, M Bui, J L Hopper, L F Fontenelle, C G Davey, C Pantelis, P Alonso, O A van den Heuvel, B J Harrison
OBJECTIVE: The question of how to best conceptualize health anxiety (HA) from a diagnostic and etiological perspective remains debated. The aim was to examine the relationship between HA and the symptoms of anxiety and obsessive-compulsive-related disorders in a normative twin population. METHOD: Four hundred and ninety-six monozygotic adult twin pairs from the Australian Twin Registry participated in the study (age, 34.4 ± 7.72 years; 59% females). Validated scales were used to assess each domain...
January 15, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29334641/do-clinically-anxious-children-cluster-according-to-their-expression-of-factors-that-maintain-child-anxiety
#8
Samantha Pearcey, Anna Alkozei, Bhismadev Chakrabarti, Helen Dodd, Kou Murayama, Suzannah Stuijfzand, Cathy Creswell
BACKGROUND: Cognitive Behaviour Therapy (CBT) is an effective treatment for childhood anxiety disorders, yet a significant proportion of children do not benefit from it. CBT for child anxiety disorders typically includes a range of strategies that may not all be applicable for all affected children. This study explored whether there are distinct subgroups of children with anxiety disorders who are characterized by their responses to measures of the key mechanisms that are targeted in CBT (i...
January 3, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29333493/a-quality-improvement-project-aimed-at-adapting-primary-care-to-ensure-the-delivery-of-evidence-based-psychotherapy-for-adult-anxiety
#9
Mark D Williams, Craig N Sawchuk, Nathan D Shippee, Kristin J Somers, Summer L Berg, Jay D Mitchell, Angela B Mattson, David J Katzelnick
Primary care patients frequently present with anxiety with prevalence ratios up to 30%. Brief cognitive-behavioural therapy (CBT) has been shown in meta-analytic studies to have a strong effect size in the treatment of anxiety. However, in surveys of anxious primary care patients, nearly 80% indicated that they had not received CBT. In 2010, a model of CBT (Coordinated Anxiety Learning and Management (CALM)) adapted to primary care for adult anxiety was published based on results of a randomised controlled trial...
2018: BMJ Open Quality
https://www.readbyqxmd.com/read/29333196/brief-report-reduced-anxiety-following-pivotal-response-treatment-in-young-children-with-autism-spectrum-disorder
#10
Jiedi Lei, Denis G Sukhodolsky, Sebiha M Abdullahi, Megan L Braconnier, Pamela Ventola
Up to 40% of children with Autism Spectrum Disorder (ASD) exhibit co-occurring anxiety symptoms. Despite recent success in mitigating anxiety symptoms in school-aged children with ASD (mean age >9 years) using adapted versions of Cognitive Behavioural Therapy, little is known about potential treatment outcomes for younger children. To address the gap in the literature, this open-label study evaluated change in anxiety following a 16-week open-label trial of Pivotal Response Treatment (PRT) in children with ASD aged 4-8 years...
November 2017: Research in Autism Spectrum Disorders
https://www.readbyqxmd.com/read/29332631/treatment-utilization-and-barriers-to-treatment-among-individuals-with-olfactory-reference-syndrome-ors
#11
Jennifer L Greenberg, Noah C Berman, Valerie Braddick, Rachel Schwartz, Suraj S Mothi, Sabine Wilhelm
OBJECTIVE: Olfactory reference syndrome (ORS) is characterized by a preoccupation that one is emitting a foul or offensive odor. Despite the profound psychosocial impact of ORS, many patients do not receive appropriate treatment, and there is no empirical research on treatment-seeking behavior in ORS. This study investigated treatment utilization patterns and barriers to treatment in individuals with ORS. METHOD: 253 subjects completed an online survey between January-March 2010...
February 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29330217/a-systematic-review-of-network-meta-analyses-for-pharmacological-treatment-of-common-mental-disorders
#12
REVIEW
Taryn Williams, Dan J Stein, Jonathan Ipser
QUESTION: Network meta-analyses (NMAs) of treatment efficacy across different pharmacological treatments help inform clinical decision-making, but their methodological quality may vary a lot depending also on the quality of the included primary studies. We therefore conducted a systematic review of NMAs of pharmacological treatment for common mental disorders in order to assess the methodological quality of these NMAs, and to relate study characteristics to the rankings of efficacy and tolerability...
January 12, 2018: Evidence-based Mental Health
https://www.readbyqxmd.com/read/29329058/association-of-comorbid-personality-disorders-with-clinical-characteristics-and-outcome-in-a-randomized-controlled-trial-comparing-two-psychotherapies-for-early-onset-persistent-depressive-disorder
#13
Nele Erkens, Elisabeth Schramm, Levente Kriston, Martin Hautzinger, Martin Härter, Ulrich Schweiger, Jan Philipp Klein
BACKGROUND: Persistent depressive disorder (PDD) is associated with high rates of comorbid personality disorders (PD). The association of comorbid PD and clinical characteristics has not been systematically studied in PDD. Results regarding effects on treatment outcome are heterogeneous. METHODS: We analyzed the association of comorbid personality disorders with clinical characteristics and outcome in a randomized controlled trial comparing the disorder-specific Cognitive Behavioral Analysis System of Psychotherapy (CBASP) with nonspecific supportive psychotherapy (SP) in patients with early-onset PDD...
January 4, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29327281/effect-of-early-natal-supplementation-of-paracetamol-on-attenuation-of-exotoxin-endotoxin-induced-pyrexia-and-precipitation-of-autistic-like-features-in-albino-rats
#14
Abdulaziz S Saeedan, Indu Singh, Mohd Nazam Ansari, Manjari Singh, Jitendra K Rawat, Uma Devi, Swetlana Gautam, Rajnish K Yadav, Gaurav Kaithwas
The present study was aimed to test the hypothesis that paracetamol (PCM) can precipitate autistic like features when used to counteract vaccine-induced fever using experimental rat pups. The pups were treated with measles mumps rubella (MMR) vaccine, diphtheria tetanus and pertussis (DPT) vaccines and lipopolysaccharide (LPS) with subsequent PCM treatment. The pups were evaluated for postnatal growth (weight gain, eye opening) and behavior alterations (swimming performance, olfactory discrimination, negative geotaxis, nociception, and locomotor activity) by performing battery of neurobehavioral test...
January 11, 2018: Inflammopharmacology
https://www.readbyqxmd.com/read/29324369/early-life-social-stress-and-resting-state-functional-connectivity-in-postpartum-rat-anterior-cingulate-circuits
#15
Benjamin C Nephew, Marcelo Febo, Wei Huang, Luis M Colon-Perez, Laurellee Payne, Guillaume L Poirier, Owen Greene, Jean A King
INTRODUCTION: Continued development and refinement of resting state functional connectivity (RSFC) fMRI techniques in both animal and clinical studies has enhanced our comprehension of the adverse effects of stress on psychiatric health. The objective of the current study was to assess both maternal behavior and resting state functional connectivity (RSFC) changes in these animals when they were dams caring for their own young. It was hypothesized that ECSS exposed dams would express depressed maternal care and exhibit similar (same networks), yet different specific changes in RSFC (different individual nuclei) than reported when they were adult females...
January 2, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29321077/social-anxiety-disorder-looking-back-and-moving-forward
#16
Matthew P Hyett, Peter M McEvoy
Fifty years have passed since social anxiety disorder (SAD) was first differentiated from other phobias. In the years since research has largely aligned with the zeitgeist of categorical classificatory frameworks, and has spanned identifying causes, maintenance factors and innovative interventions. Despite significant advances in the field, the capacity to conceptualise SAD as an independent entity is limited given the heterogeneity and dimensionality of diagnostic criteria, high rates of comorbidity, and non-specificity of aetiological mechanisms, maintaining factors and approaches to treatment...
January 11, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29320378/an-examination-of-fluoxetine-for-the-treatment-of-selective-mutism-using-a-nonconcurrent-multiple-baseline-single-case-design-across-5-cases
#17
Justin A Barterian, Joel M Sanchez, Jed Magen, Allison K Siroky, Brittany L Mash, John S Carlson
This study examined the utility of fluoxetine in the treatment of 5 children, aged 5 to 14 years, diagnosed with selective mutism who also demonstrated symptoms of social anxiety. A nonconcurrent, randomized, multiple-baseline, single-case design with a single-blind placebo-controlled procedure was used. Parents and the study psychiatrist completed multiple methods of assessment including Direct Behavior Ratings and questionnaires. Treatment outcomes were evaluated by calculating effect sizes for each participant as an individual and for the participants as a group...
January 2018: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/29316012/quality-of-life-with-ablation-or-medical-therapy-for-ventricular-arrhythmias-a-substudy-of-vanish
#18
Lorne J Gula, Steve Doucette, Peter Leong-Sit, Anthony S L Tang, Ratika Parkash, Jean-Francois Sarrazin, Bernard Thibault, Vidal Essebag, Stanley K Tung, Marc W Deyell, Jean-Marc Raymond, Chris Lane, Pablo B Nery, George D Veenhuyzen, Damian P Redfearn, Jeffrey S Healey, Jean-Francois Roux, Karen Giddens, John L Sapp
BACKGROUND/OBJECTIVE: We compared health-related quality of life (HRQoL) in patients randomized to escalated-therapy and those randomized to ablation for ventricular tachycardia in the VANISH trial. METHODS: HRQoL was assessed among VANISH patients at baseline and 3-, 6- and 12-month follow-up visits. Four validated instruments were used: the SF-36, the ICD Concerns questionnaire (ICDC), the Hospital Anxiety and Depression Scale (HADS), and the EuroQol five dimensions questionnaire (EQ-5D)...
January 9, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29310641/health-services-research-in-patients-with-breast-cancer-camiss-prospective-study-protocol-for-an-observational-prospective-study
#19
Susana García-Gutierrez, Miren Orive, Cristina Sarasqueta, Maria Jose Legarreta, Nerea Gonzalez, Maximino Redondo, Amado Rivero, Pedro Serrano-Aguilar, Xavier Castells, Jose Maria Quintana, Maria Sala
BACKGROUND: Though breast cancer remains a major health problem, there is a lack of information on health care provided to patients with this disease and associated costs. In addition, there is a need to update and validate risk stratification tools in Spain. Our purpose is to evaluate the health services provided for breast cancer in Spain, from screening and diagnosis to treatment and prognosis. METHODS: Prospective cohort study involving 13 hospitals in Spain with a follow-up period of up to 5 years after diagnostic biopsy...
January 8, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29307056/predictors-of-quality-of-life-and-psychological-health-in-infertile-couples-the-moderating-role-of-duration-of-infertility
#20
Maria Clelia Zurlo, Maria Francesca Cattaneo Della Volta, Federica Vallone
PURPOSE: To investigate the influence of individual characteristics (age, gender, educational level, coping strategies), perceived couple's Dyadic Adjustment, type of diagnosis and duration of infertility on self-reported quality of life (QoL) and psychological health in infertile couples, examining the potential moderating role of duration of infertility. METHODS: A questionnaire composed by socio-demographics, Coping Orientations to Problem Experienced, Dyadic Adjustment Scale, FertiQoL, State-Trait Anxiety Inventory and Edinburgh Depression Scale was submitted to 206 couples undergoing infertility treatments...
January 6, 2018: Quality of Life Research
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