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Lymphedema treatment

Lívia Maria Pereira de Godoy, Paula Pereira de Godoy Capeletto, Maria de Fátima Guerreiro Godoy, Jose Maria Pereira de Godoy
Objective: The aim of the present study is to report on the reduction of edema of lymphedematous arms just by treating the lower limbs. Methods: A 16-year-old girl reported that she has started having right lower limb edema at the age of three. At age 13, she performed a lymphoscintigraphy that confirmed the diagnosis of primary lymphedema of the four limbs. Recently she sought treatment at the Clínica Godoy in São Jose do Rio Preto where she was submitted to intensive treatment for eight hours per day for five days using manual (Godoy & Godoy technique) and mechanical lymphatic therapy (RA Godoy® ) of the lower limbs, cervical lymphatic therapy (cervical stimulation), and the continuous use of a grosgrain stocking...
2018: Case Reports in Pediatrics
Yanira Sanchez-De la Torre, Rita Wadeea, Victoria Rosas, Karen L Herbst
Background Lipedema is a chronic disorder presenting in women during puberty or other times of hormonal change such as childbirth or menopause, characterized by symmetric enlargement of nodular, painful subcutaneous adipose tissue (fat) in the limbs, sparing the hands, feet and trunk. Healthcare providers underdiagnose or misdiagnose lipedema as obesity or lymphedema. Materials and methods The benefits (friend) and negative aspects (foe) of lipedema were collected from published literature, discussions with women with lipedema, and institutional review board approved evaluation of medical charts of 46 women with lipedema...
March 9, 2018: Hormone Molecular Biology and Clinical Investigation
Ting Bao, Wanqing Iris Zhi, Emily A Vertosick, Qing Susan Li, Janice DeRito, Andrew Vickers, Barrie R Cassileth, Jun J Mao, Kimberly J Van Zee
PURPOSE: Approximately 20% of breast cancer survivors develop breast cancer-related lymphedema (BCRL), and current therapies are limited. We compared acupuncture (AC) to usual care wait-list control (WL) for treatment of persistent BCRL. METHODS: Women with moderate BCRL lasting greater than six months were randomized to AC or WL. AC included twice weekly manual acupuncture over six weeks. We evaluated the difference in circumference and bioimpedance between affected and unaffected arms...
March 8, 2018: Breast Cancer Research and Treatment
Elizabeth O Kenworthy, Jonas A Nelson, Richa Verma, JeanJacques Mbabuike, Babak J Mehrara, Joseph H Dayan
BACKGROUND AND OBJECTIVES: Orthotopic vascularized lymph node transplant has been successfully used to treat lymphedema. A second, heterotopic lymph node transplant in the distal extremity may provide further improvement. The vascularized omentum lymphatic transplant (VOLT) provides adequate tissue for two simultaneous flap transfers to one limb. The purpose of this study was to review our experience with this technique. METHODS: We conducted a retrospective study of patients who underwent VOLT, with a subgroup analysis of patients who underwent double VOLT...
March 8, 2018: Journal of Surgical Oncology
Brigid K Killelea, Jessica B Long, Weixiong Dang, Sarah S Mougalian, Suzanne B Evans, Cary P Gross, Shi-Yi Wang
PURPOSE: To examine the associations between sentinel lymph node biopsy (SLNB) and complications among older patients who underwent breast-conserving surgery (BCS) for ductal carcinoma in situ (DCIS). METHODS: We identified women from the Surveillance, Epidemiology, and End Results-Medicare dataset aged 67-94 years diagnosed during 1998-2011 with DCIS who underwent BCS as initial treatment. We assessed incidence of complications, including lymphedema, wound infection, seroma, or pain, within 9 months of diagnosis...
March 7, 2018: Annals of Surgical Oncology
Karen Steindorf, Martina E Schmidt, Philipp Zimmer
A growing number of literature reports positive effects of physical activity and exercise. These effects concern prevention, mortality and progress of cancer. Furthermore they show a reduction of disease- and treatment-specific side effects, which implies a better patients' quality of life. Evidence shows a decreased mortality risk in patients with physically active cancer of colon, breast, ovaries and prostate. Activity recommendations for patients with cancer do not differ from those for healthy persons...
March 2018: Deutsche Medizinische Wochenschrift
Manu Beerens, Xabier L Aranguren, Benoit Hendrickx, Wouter Dheedene, Tom Dresselaers, Uwe Himmelreich, Catherine Verfaillie, Aernout Luttun
Lymphatic capillary growth is an integral part of wound healing, yet, the combined effectiveness of stem/progenitor cells on lymphatic and blood vascular regeneration in wounds needs further exploration. Stem/progenitor cell transplantation also emerged as an approach to cure lymphedema, a condition caused by lymphatic system deficiency. While lymphedema treatment requires lymphatic system restoration from the capillary to the collector level, it remains undetermined whether stem/progenitor cells support a complex regenerative response across the entire anatomical spectrum of the system...
March 1, 2018: Scientific Reports
Thomas W Fuller, Katherine M Theisen, Anup Shah, Paul J Rusilko
PURPOSE OF REVIEW: Adult acquired buried penis is a morbid condition characterized by complete entrapment of the phallus as a result of morbid obesity, post-surgical cicatrix formation, or primary genital lymphedema. Hygienic voiding is not possible and urinary dribbling is frequent with accompanying inflammation, skin breakdown, and infection from the chronic moisture. The end result is penile skin fibrosis resulting in permanent functional loss. Herein, we describe the etiology of adult acquired buried penis, advances in its surgical management, and quality of life outcomes with treatment...
February 28, 2018: Current Urology Reports
Johnson Chia-Shen Yang, Shao-Chun Wu, Min-Hsien Chiang, Wei-Che Lin
Lymphaticovenous anastomosis is one of the main surgical treatments nowadays for alleviating lymphedema. A successful lymphaticovenous anastomosis relies on being able to identify "functional" lymphatic collecting vessels that are still capable of transporting lymph, and a nearby vein that is, ideally, reflux-free. This is a retrospective study. A total of 28 lymphedema patients were enrolled from October of 2016 to March of 2017 in Kaohsiung Chang Gung Hospital, Kaohsiung, Taiwan. A noninvasive vein visualizer was used to preselect reflux-free veins for lymphaticovenous anastomosis from five female patients...
March 2018: Plastic and Reconstructive Surgery
Mahrooyeh Hadizadeh, Seiied Mojtaba Mohaddes Ardebili, Mansoor Salehi, Chris Young, Fariborz Mokarian, James McClellan, Qin Xu, Mohammad Kazemi, Elham Moazam, Behzad Mahaki, Maziar Ashrafian Bonab
Lymphedema is a condition resulting from mutations in various genes essential for lymphatic development and function, which leads to obstruction of the lymphatic system. Secondary lymphedema is a progressive and incurable condition, most often manifesting after surgery for breast cancer. Although its causation appears complex, various lines of evidence indicate that genetic predisposition may play a role. Previous studies show that mutations in connexin 47 are associated with secondary lymphedema. We have tested the hypothesis that connexin 37 gene mutations in humans are associated with secondary lymphedema following breast cancer surgery...
February 22, 2018: Biomedicines
Anouk J M Cornelissen, Melissa Kool, Xavier H A Keuter, Esther M Heuts, Andrzej A Piatkowski de Grzymala, René R W J van der Hulst, Shan Shan Qiu
PURPOSE: Lymphedema of the arm is one of the most common and underestimated side effects of breast cancer treatment. It is known to negatively affect the quality of life (QoL) in breast cancer survivors. However, there are multiple questionnaires used to measure QoL in lymphedema patients. The current study aimed to determine the most complete and accurate questionnaire. METHODS: A systematic literature search in Cochrane Library database CENTRAL, MEDLINE, and EMBASE was conducted in August 2016 by two independent researchers...
February 13, 2018: Lymphatic Research and Biology
Neel S Iyer, Brenda Cartmel, Louis Friedman, Fangyong Li, Yang Zhou, Elizabeth Ercolano, Maura Harrigan, Linda Gottlieb, Ruth McCorkle, Peter E Schwartz, Melinda L Irwin
BACKGROUND: Lymphedema is a poorly understood side effect of gynecologic cancer treatment. This study was designed to determine the prevalence of lower limb lymphedema (LLL) in a sample of ovarian cancer survivors via 3 different diagnostic methods and to assess the effect of a randomized exercise intervention. METHODS: Physically inactive ovarian cancer survivors (n = 95) were enrolled in a 6-month randomized trial of exercise (primarily brisk walking) versus attention control...
February 13, 2018: Cancer
Isano Hase, Kazuhiro Kurasawa, Hidenori Takizawa, Bunpei Yamaguchi, Hideo Sakuma, Yoshiki Ishii
Yellow nail syndrome (YNS) pleurisy is often difficult to control, and pathological examinations have rarely been reported. We herein report a case of bucillamine-induced YNS in which histopathology of the parietal pleura revealed hyperplasia of the lymphoid follicles and lymphangiectasia. Even after the discontinuation of bucillamine, the pleurisy and lymphedema showed no change. Based on the histopathological findings showing similarity to rheumatoid pleurisy, we administered corticosteroid treatments, and both the pleurisy and lymphedema improved...
February 9, 2018: Internal Medicine
Christine J Moffatt, Debra C Doherty, Peter J Franks, Peter S Mortimer
BACKGROUND: Chronic edema care is patchy and of variable quality internationally. This study was undertaken to develop and evaluate a system of care that would provide for patients within a geographical area of London (Wandsworth), United Kingdom. METHODS AND RESULTS: A prospective cohort design with intervention of a new service design following a 6-month baseline period. Patients were identified through health professionals. A stratified random sample was drawn from all patients and an implementation strategy developed...
February 2018: Lymphatic Research and Biology
Joseph M Aulino, Elizabeth M Wulff-Burchfield, Mary S Dietrich, Sheila H Ridner, Kenneth J Niermann, Jie Deng, Bethany A Rhoten, Jennifer K Doersam, Lee Ann Jarrett, Kyle Mannion, Barbara A Murphy
BACKGROUND: The late effect continuum of lymphedema and fibrosis (LEF) affects more than 70% of patients after treatment for head and neck cancer (HNC). LEF is associated with symptom burden and decreased function and quality of life. Although surveillance imaging is common posttreatment, objective assessment of soft tissues is not, likely due to the lack of objective evaluation methods and understanding of the significance of LEF. We undertook the development of a tool to measure LEF using CT scans in HNC patients...
February 2018: Lymphatic Research and Biology
Ligita Paskeviciute Froeding, Elfriede Greimel, Anne Lanceley, Anne Oberguggenberger, Claudia Schmalz, Vesna Bjelic Radisic, Andy Nordin, Razvan Galalaei, Karin Kuljanic, Ingvild Vistad, Tine Henrichsen Schnack, Pernille Tine Jensen
OBJECTIVES: Vulva cancer (VC) treatment carries a high risk of severe late effects that may have a negative impact on quality of life (QoL). Patient-reported outcome measures (PROMs) are increasingly used when evaluating disease- and treatment-specific effects. However, the adequacy of measures used to assess sequelae and QoL in VC remains unclear. The aims of the present study were to evaluate disease- and treatment-related effects as measured by PROMs in VC patients and to identify available VC-specific PROMs...
February 8, 2018: International Journal of Gynecological Cancer
Eunice Jeffs, Emma Ream, Cath Taylor, Debra Bick
OBJECTIVE: To identify the effect of decongestive lymphedema treatment on excess arm volume or patient-centered outcomes in women presenting within either 12 months or a mean nine months of developing arm lymphedema following breast cancer treatment. INTRODUCTION: Lymphedema is a common consequence of breast cancer treatment requiring life-long treatment to reduce symptoms and prevent complications. Currently, evidence to inform the optimal decongestive lymphedema treatment package is lacking...
February 2018: JBI Database of Systematic Reviews and Implementation Reports
Li Zou, Feng-Hua Liu, Pei-Pei Shen, Yan Hu, Xiao-Qian Liu, Ying-Ying Xu, Qi-Liang Pen, Bei Wang, Ya-Qun Zhu, Ye Tian
PURPOSE: To investigate the incidence rate, severity and risk factors of related lymphedema in breast cancer survivors. METHODS: A 2-year follow-up prospective study of 387 women who had operation from four hospitals from January 1, to December 31, 2014 was conducted. Limb volume was measured by circumference and symptoms were measured using questionnaires pre-treatment and 1, 3, 6, 12, 18, 24 months after surgery separately. The incidence rates and the severity of lymphedema were evaluated, respectively...
February 3, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
C Cereijo-Garea, S Pita-Fernández, B Acea-Nebril, R Rey-Villar, A García-Novoa, C Varela-Lamas, S Builes-Ramirez, T Seoane-Pillado, V Balboa-Barreiro
AIMS AND OBJECTIVES: To analyze quality of life and satisfaction after immediate breast reconstruction due to cancer and its determining factors. BACKGROUND: Studying breast reconstruction is important because of its frequency and variability. In addition to the surgical results, it is necessary to analyze the quality of life and patient satisfaction using a specific tool. DESIGN-METHODS: An ambispective design was used (n=101;α=0.05;precision=10%), studying anthropometric, socio-cultural data, Fagerström test, and the BREAST-Q© questionnaire...
February 3, 2018: Journal of Clinical Nursing
Trevor S Mafu, Alison V September, Delva Shamley
Shoulder morbidity is a well-documented sequela of breast cancer treatment, which includes various manifestations such as pain, reduced range of motion, and lymphedema, among others. The multifactorial nature of such morbidities has long been appreciated, and research on reliable risk predictors of development thereof still continues. Previous studies have demonstrated the potential of different types of physical therapy to treat such shoulder problems, and the integration of such interventions into routine care for breast cancer survivors is a requirement in most high-income countries...
2018: Cancer Management and Research
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