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Lymphedema treatment

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https://www.readbyqxmd.com/read/28626257/multi-center-rater-blinded-study-of-early-intervention-with-the-hand-incubator-for-breast-cancer-related-lymphedema-the-beat-edema-trial-proposal-of-a-research-protocol
#1
Hisao Ishii, Katsuyuki Iwatsuki, Masahiro Tatebe, Hitoshi Hirata, Toyone Kikumori, Nobuyuki Tsunoda, Ikuo Hyodo, Tomoko Ogawa, Naoki Unno
Postoperative lymphedema is considered irreversible once it has developed, and significantly lowers the patient's quality of life. However, lymphatic function has recently been clarified, and it is possible that lymphedema can be cured if early treatment is started. This two-arm randomized clinical trial (UMIN000026124) will prospectively evaluate 24 patients with early-stage breast cancer-related lymphedema at the Nagoya University Hospital and Aichi Cancer Center Hospital. The eligibility criteria will be patients who are diagnosed with stage 0-1 breast cancer-related lymphedema, as defined by the International Society of Lymphology, within 12 weeks after breast cancer surgery...
February 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/28624154/lymphedema-following-gynecological-cancer-results-from-a-prospective-longitudinal-cohort-study-on-prevalence-incidence-and-risk-factors
#2
Sandra C Hayes, Monika Janda, Leigh C Ward, Hildegard Reul-Hirche, Megan L Steele, Johnathan Carter, Michael Quinn, Bruce Cornish, Andreas Obermair
OBJECTIVE: Cancer-related lymphedema is a debilitating condition that adversely influences function, health and quality of life. The purpose of this study was to assess the prevalence, incidence, and risk factors of lower-limb lymphedema pre- through to 24months post-surgery for gynecological cancer. METHODS: A clinic-based sample of women (n=408) with gynecological cancer participated in a prospective, longitudinal study (2008-2011) using self-reported measures (swelling in one or both legs) and objectively measured lymphedema (bioimpedance spectroscopy) at baseline (pre-surgery), six weeks-three months, 6-12months, and 15-24months post-surgery...
June 14, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28621805/noninvasive-screening-test-for-detecting-early-stage-lymphedema-using-follow-up-computed-tomography-imaging-after-cancer-treatment-and-results-of-treatment-with-lymphaticovenular-anastomosis
#3
Shinsuke Akita, Fusa Ogata, Ichiro Manabe, Akira Mitsuhashi, Rikiya Nakamura, Yoshihisa Yamaji, Yoshitaka Kubota, Nobuyuki Mitsukawa
BACKGROUND: Although early detection is valuable for secondary lymphedema treatment, existing screening tests are not popular. This study aimed to propose a novel method of screening lymphedema patients based on the thickness of the subcutaneous fat measured with perioperative computed tomography (CT) and present the results from evaluation of patients who underwent those examinations was performed. METHOD: The medical records of 96 gynecological cancer patients and 189 breast cancer patients, whose lymphatic function was assessed with indocyanine green lymphography, were reviewed...
June 16, 2017: Microsurgery
https://www.readbyqxmd.com/read/28617750/skin-and-wound-care-in-lymphedema-patients-a-taxonomy-primer-and-literature-review
#4
Caroline E Fife, Wade Farrow, Adelaide A Hebert, Nathan C Armer, Bob R Stewart, Janice N Cormier, Jane M Armer
BACKGROUND: Lymphedema is a condition of localized protein-rich swelling from damaged or malfunctioning lymphatics. Because the immune system is compromised, there is a high risk of infection. Infection in patients with lymphedema may present in a variety of ways. OBJECTIVE: The goals of this review were to standardize the terminology of skin breakdown in the context of lymphedema, synthesize the available information to create best practice recommendations in support of the American Lymphedema Framework Project update to its Best Practices document, and create recommendations for further research...
July 2017: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/28616845/neoadjuvant-therapy-for-breast-cancer-established-concepts-and-emerging-strategies
#5
REVIEW
Tessa G Steenbruggen, Mette S van Ramshorst, Marleen Kok, Sabine C Linn, Carolien H Smorenburg, Gabe S Sonke
In the last decade, the systemic treatment approach for patients with early breast cancer has partly shifted from adjuvant treatment to neoadjuvant treatment. Systemic treatment administration started as a 'one size fits all' approach but is currently customized according to each breast cancer subtype. Systemic treatment in a neoadjuvant setting is at least as effective as in an adjuvant setting and has several additional advantages. First, it enables response monitoring and provides prognostic information; second, it downstages the tumor, allowing for less extensive surgery, improved cosmetic outcomes, and reduced postoperative complications such as lymphedema; and third, it enables early development of new treatment strategies by using pathological complete remission as a surrogate outcome of event-free and overall survival...
June 14, 2017: Drugs
https://www.readbyqxmd.com/read/28609348/factors-associated-with-lymphosclerosis-an-analysis-on-962-lymphatic-vessels
#6
Takumi Yamamoto, Nana Yamamoto, Hidehiko Yoshimatsu, Mitsunaga Narushima, Isao Koshima
BACKGROUND: Lymphaticovenular anastomosis (LVA) is a useful treatment option for compression-refractory lower extremity lymphedema (LEL), but its efficacy largely depends on severity of lymphosclerosis. To maximize LVA efficacy, it is important to elucidate factors associated with severe lymphosclerosis (SLS). METHODS: Medical charts of 134 LEL patients who underwent preoperative indocyanine green (ICG) lymphography and LVA were reviewed to obtain data of clinical demographics, ICG lymphography findings, and intraoperative findings...
June 12, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28608029/the-efficacy-of-lymphaticovenular-anastomosis-in-breast-cancer-related-lymphedema
#7
H Winters, H J P Tielemans, M Hameeteman, V A A Paulus, C H Beurskens, N J Slater, D J O Ulrich
INTRODUCTION: Lymphedema can be a debilitating condition, causing a great decrease in a person's quality of life (QoL). Treatment with lymphaticovenular anastomosis (LVA), in which an anastomosis is created between the lymphatic and venous system, may attenuate lymphedema symptoms and reduce swelling. In this study, we share the results using LVA to treat breast cancer-related lymphedema (BCRL) at our institution. MATERIALS AND METHODS: Patients were eligible for inclusion if they suffered from unilateral BCRL, if functional lymphatics were available, if compression therapy was used for at least 6 months, and if the follow-up was 12 months at minimum...
June 12, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28606600/maximizing-functional-outcomes-in-head-and-neck-cancer-survivors-assessment-and-rehabilitation
#8
REVIEW
Nausheen Jamal, Barbara Ebersole, Andrew Erman, Dinesh Chhetri
With increases in survivorship for patients with head and neck cancer, attention is turning to quality-of-life issues for survivors. Care for these patients is multifaceted. Dysphagia and issues of voice/speech, airway obstruction, neck and shoulder dysfunction, lymphedema, and pain control are important to address. Rehabilitation interventions are patient-specific and aim to prevent, restore, compensate, and palliate symptoms and sequelae of treatment for optimal functioning. Central to providing comprehensive interdisciplinary care are the head and neck surgeon, laryngologist, and speech-language pathologist...
June 9, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28600034/the-video-endoscopy-inguinal-lymphadenectomy-for-vulvar-cancer-a-pilot-study
#9
Angelica Naldini, Cristiano Rossitto, Fabio Pacelli, Giuseppe Vizzielli, Giuseppe Campagna, Maria Cristina Moruzzi, Giovanni Scambia
OBJECTIVE: This prospective pilot study aims to validate feasibility, efficacy and safeness of the innovative technique of video endoscopy inguinal lymphadenectomy (VEIL) and compare it to open inguinal lymphadenectomy (OIL) in the staging and treatment of vulvar cancer (VC). MATERIAL AND METHODS: All patients affected by VC suitable for bilateral inguinal-femoral lymphadenectomy were prospectively enrolled and submitted to VEIL on one side and OIL contralaterally, sparing the saphenous vein...
June 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28594742/outcomes-of-lymphedema-microsurgery-for-breast-cancer-related-lymphedema-with-or-without-microvascular-breast-reconstruction
#10
Holger Engel, Chia-Yu Lin, Jung-Ju Huang, Ming-Huei Cheng
OBJECTIVE: This study investigated the outcome of lymphedema microsurgery with or without microsurgical breast reconstruction for breast cancer-related lymphedema (BCRL). BACKGROUND: Complete decongestive therapy, lymphovenous anastomosis, and vascularized lymph node flap transfer are the 3 major treatment modalities for BCRL. Releasing axillary contracture and transferring a free flap may potentially improve the BCRL. METHODS: Between 2004 and 2015, 124 patients with BCRL who underwent 3 treatment modalities without or with microsurgical breast reconstruction were included in this study as groups I and II, respectively...
June 7, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28582379/laparoscopic-gastroepiploic-lymphovascular-pedicle-harvesting-for-the-treatment-of-extremity-lymphedema-a-novel-technique
#11
Michael E Johnston, Juan Socas, JoAnna L Hunter, Eugene P Ceppa
Vascularized lymph node transfers have multiple donor sites with risk of iatrogenic lymphedema. We sought to describe in detail a surgical technique that is safe, reproducible, and efficient in harvesting gastroepiploic vascularized lymph nodes using real-time indocyanine green (ICG) fluorescent imaging. Photographs and video were acquired from a case to depict a step-by-step approach. ICG was endoscopically injected into the submucosa of the greater curvature of the stomach at the outset of the procedure. A laparoscopic harvest of the gastroepiploic vascular pedicle and lymph nodes ensued with the assistance of fluorescent imaging...
June 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28573790/a-comparison-of-programmable-and-non-programmable-compression-devices-for-treatment-of-lymphedema-using-an-administrative-health-outcomes-dataset
#12
P Karaca-Mandic, A T Hirsch, S G Rockson, S H Ridner
BACKGROUND: Patients with lymphedema suffer lifelong swelling and recurrent cellulitis despite use of complete decongestive therapy. Pneumatic compression devices (PCDs), including non-programmable and programmable devices that meet individual patient needs, support long term self-care in the home. Yet, to date, no direct comparison of their relative benefits has been available. OBJECTIVE: Patients who acquired either a non-programmable device (NP-PCD) or a dynamic pressure programmable device (P-PCD; Flexitouch(®) ) were evaluated to compare associated clinical and health utilization outcomes pre/post-device acquisition...
June 2, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28570585/prevalence-of-depression-and-associated-clinical-and-socio-demographic-factors-in-people-living-with-lymphatic-filariasis-in-plateau-state-nigeria
#13
James Obindo, Jibril Abdulmalik, Emeka Nwefoh, Michael Agbir, Charles Nwoga, Aishatu Armiya'u, Francis Davou, Kurkat Maigida, Emmanuel Otache, Ajuma Ebiloma, Samuel Dakwak, John Umaru, Elisha Samuel, Christopher Ogoshi, Julian Eaton
BACKGROUND: Lymphatic filariasis is a chronic, disabling and often disfiguring condition that principally impacts the world's poorest people. In addition to the well-recognised physical disability associated with lymphedema and hydrocele, affected people often experience rejection, stigma and discrimination. The resulting emotional consequences are known to impact on the quality of life and the functioning of the affected individuals. However, the management of this condition has focused on prevention and treatment through mass drug administration, with scant attention paid to the emotional impact of the condition on affected individuals...
June 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28570444/mastering-lymphatic-microsurgery-a-new-training-model-in-living-tissue
#14
Corrado Cesare Campisi, Lucian P Jiga, Melissa Ryan, Pietro G di Summa, Corradino Campisi, Mihai Ionac
BACKGROUND: Advanced microsurgical techniques have emerged as a promising approach for the treatment of lymphedema, but achieving international standards is limited by a scarcity of adequate training models. The purpose of this report is to describe our in vivo porcine training model for microsurgery. STUDY DESIGN: Five female common-breed pigs (Sus scrofa domesticus) weighing 20 to 28 kg were placed under general anesthesia, and blue patent violet dye was injected to highlight lymphatic structures and prepare the pigs for anatomical exploration and microsurgery...
May 31, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28567405/applying-a-mobile-survey-tool-for-assessing-lymphatic-filariasis-morbidity-in-mtwara-municipal-council-of-tanzania
#15
Upendo J Mwingira, Philip Downs, Cecilia Uisso, Maria Chikawe, Matthieu Sauvage-Mar, Mwelecele N Malecela, Kathryn Crowley, Jeremiah M Ngondi
BACKGROUND: A number of methods have been used to estimate lymphatic filariasis (LF) morbidity, including: routine programmatic data, cluster random surveys and the "town crier" method. Currently, few accurate data exist on the global LF morbidity burden in Tanzania. We aimed to estimate prevalence of lymphedema and hydrocele in Mtwara Municipal Council using mobile phone based survey. METHODS: A cross-sectional survey was conducted among adults of Mtwara Municipal council with access to mobile phones...
2017: MHealth
https://www.readbyqxmd.com/read/28559146/translation-and-adaptation-of-the-radiotherapy-edema-rating-scale-to-brazilian-portuguese
#16
Débora Dos Santos Queija, Lica Arakawa-Sugueno, Bruna Mello Chamma, Marco Aurélio Vamondes Kulcsar, Rogério Aparecido Dedivitis
INTRODUCTION: Internal lymphedema is one of the sequelae of head and neck cancer treatment that can lead to varying degrees of swallowing, speech, and respiration alterations. The Radiotherapy Edema Rating Scale, developed by Patterson et al., is a tool used to evaluate pharyngeal and laryngeal edema. OBJECTIVE: To translate into Brazilian Portuguese, to culturally adapt and test this scale in patients undergoing treatment for head and neck cancer. METHODS: The process followed the international guidelines and translation steps by two head and neck surgeons and back-translation performed independently by two North-American natives...
May 9, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28551895/-sentinel-lymph-nodes-dissection-in-gynecological-malignancies
#17
REVIEW
Yael Naaman, Limor Goldenhersh, Alon Ben-Arie
During the last decade sentinel lymph nodes biopsy has become an essential part of primary surgical treatment in a number of malignancies including breast cancer, melanoma and head-and-neck malignancies. Dye or radioactive substances are injected at the primary tumor site, followed by pre-operative and intra-operative mapping. During surgery only positive lymph nodes are being dissected instead of a complete dissection of the lymphatic basin. The advantages of sentinel lymph nodes dissection are reducing the side effects of extensive lymph nodes dissection, while maintaining high detection rates and sensitivity in identifying cases with lymphatic tumor spread...
February 2017: Harefuah
https://www.readbyqxmd.com/read/28543381/ileocecal-vascularized-lymph-node-transfer-for-the-treatment-of-extremity-lymphedema-a-case-report
#18
Pedro Ciudad, Oscar J Manrique, Mouchammed Agko, En-Wei Liu, Wei-Ling Chang, Matthew Sze-Wei Yeo, Tony Chieh-Ting Huang, Ram M Chilgar, Hung-Chi Chen
Vascularized lymph node (VLN) transfer has been of high interest in the past decade for the treatment of lymphedema, since it has been shown to be effective in reducing limb volumes, decreasing infectious episodes and improving quality of life. Multiple donor sites have been described in the quest for the optimal one. Herein, we describe a novel lymph node flap option based on the ileocolic artery and vein. The ileocecal vascularized lymph node (IC-VLN) flap was used in the management of a 33-year-old male patient with lower extremity lymphedema secondary to left inguinal trauma...
May 24, 2017: Microsurgery
https://www.readbyqxmd.com/read/28543027/the-vascularized-groin-lymph-node-flap-vgln-anatomical-study-and-flap-planning-using-multi-detector-ct-scanner-the-golden-triangle-for-flap-harvesting
#19
Assaf A Zeltzer, Alexander Anzarut, Delphine Braeckmans, Katrin Seidenstuecker, Benoit Hendrickx, Eddy Van Hedent, Moustapha Hamdi
INTRODUCTION: A growing number of surgeons perform lymph node transfers for the treatment of lymphedema. When harvesting a vascularized lymph node groin flap (VGLNF) one of the major concerns is the potential risk of iatrogenic lymphedema of the donor-site. This article helps understanding of the lymph node distribution of the groin in order to minimize this risk. MATERIALS AND METHODS: Fifty consecutive patients undergoing abdominal mapping by multi-detector CT scanner were included and 100 groins analyzed...
May 25, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28538870/liquid-silicone-used-for-esthetic-purposes-as-a-potentiator-for-occurrence-of-post-radiotherapy-genital-lymphedema-case-report
#20
Raíssa Quaiatti Antonelli, Davi Reis Calderoni, Igor Ferreira Garcia, Rafael Fantelli Stelini, Adriano Fregonesi, Paulo Kharmandayan
CONTEXT: Lymphedema consists of extracellular fluid retention caused by lymphatic obstruction. In chronic forms, fat and fibrous tissue accumulation is observed. Genital lymphedema is a rare condition in developed countries and may have primary or acquired etiology. It generally leads to urinary, sexual and social impairment. Clinical treatment usually has low effectiveness, and surgical resection is frequently indicated. CASE REPORT: We report a case of a male-to-female transgender patient who was referred for treatment of chronic genital lymphedema...
March 2017: São Paulo Medical Journal, Revista Paulista de Medicina
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