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gut feelings

Damian Roland, Sam Jones, Tim Coats, Ffion Davies
BACKGROUND: Increasing utilisation of Emergency and Acute Care services by children and young people is a worldwide trend. This is thought to be a result of parent and carer desire for more "on demand" health care assessment and not a consequence of increasing severity of disease. A bespoke acuity assessment system in our department allowed us to test this hypothesis. METHODS: This data is based on the Paediatric Observation Priority Score, a previously published and validated assessment tool designed specifically for Paediatric Emergency Care [1]...
October 14, 2016: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
Gurvinder Sahota
No abstract text is available yet for this article.
October 2016: British Journal of General Practice: the Journal of the Royal College of General Practitioners
Kelly R Klein, Frederick M Burkle, Raymond Swienton, Richard V King, Thomas Lehman, Carol S North
INTRODUCTION: After all large-scale disasters multiple papers are published describing the shortcomings of the triage methods utilized. This paper uses medical provider input to help describe attributes and patient characteristics that impact triage decisions. METHODS: A survey distributed electronically to medical providers with and without disaster experience. Questions asked included what disaster experiences they had, and to rank six attributes in order of importance regarding triage...
2016: PLoS Currents
Narayanan Kandasamy, Sarah N Garfinkel, Lionel Page, Ben Hardy, Hugo D Critchley, Mark Gurnell, John M Coates
Interoception is the sensing of physiological signals originating inside the body, such as hunger, pain and heart rate. People with greater sensitivity to interoceptive signals, as measured by, for example, tests of heart beat detection, perform better in laboratory studies of risky decision-making. However, there has been little field work to determine if interoceptive sensitivity contributes to success in real-world, high-stakes risk taking. Here, we report on a study in which we quantified heartbeat detection skills in a group of financial traders working on a London trading floor...
2016: Scientific Reports
Krzysztof Laudanski, Alpesh Patel
No abstract text is available yet for this article.
October 2016: Critical Care Medicine
Gé A Donker, Eva Wiersma, Lucas van der Hoek, Marianne Heins
BACKGROUND: General practitioners (GPs) use gut feelings to diagnose cancer in an early stage, but little is known about its impact. METHOD: Prospective cohort study of patients in 44 general practices throughout the Netherlands, from January 2010 until December 2013. GPs completed a questionnaire regarding gut feelings, patient and GP characteristics, if they noticed a cancer-related gut feeling during patient consultation. Follow-up questionnaires were sent 3 months later requesting information about the patient's diagnosis...
September 13, 2016: BMJ Open
Anthony J Hannan
Is that a rumbling I feel in my stomach? Or perhaps it is the trillions of bacteria down there who are in revolt, fomenting (or fermenting!) a microbial revolution? No active biologist or medical researcher can easily ignore the revolution in gut microbiome research in recent years. It seems that the gut microbiome, the entire microbial ecosystem occupying the gastrointestinal ecological niche, can impact almost every organ in the human body, not least of which being the brain. The gut microbiome has been found to signal to both the developing and adult mammalian brain, modulating both health and disease states (Cryan and Dinan, 2012; Mayer et al...
September 13, 2016: European Journal of Neuroscience
Sergueï O Fetissov
The life of all animals is dominated by alternating feelings of hunger and satiety - the main involuntary motivations for feeding-related behaviour. Gut bacteria depend fully on their host for providing the nutrients necessary for their growth. The intrinsic ability of bacteria to regulate their growth and to maintain their population within the gut suggests that gut bacteria can interfere with molecular pathways controlling energy balance in the host. The current model of appetite control is based mainly on gut-brain signalling and the animal's own needs to maintain energy homeostasis; an alternative model might also involve bacteria-host communications...
September 12, 2016: Nature Reviews. Endocrinology
Carina Remmers, Johannes Michalak
Whereas in basic research, intuition has become a topic of great interest, clinical research and depression research in specific have not applied to the topic of intuition, yet. This is astonishing because a well-known phenomenon during depression is that patients have difficulties to judge and decide. In contrast to healthy individuals who take most daily life decisions intuitively (Kahneman, 2011), depressed individuals seem to have difficulties to come to fast and adaptive decisions. The current article pursues three goals...
2016: Frontiers in Psychology
Priyadarshika Hettiarachchi, A Rajitha Wickremasinghe, Gary S Frost, Kemal I Deen, Ajith A Pathirana, Kevin G Murphy, SriLal D Jayaratne
OBJECTIVE: To assess appetite and gut hormone levels in patients following partial (PR) or total resection (TR) of the large bowel. METHODS: A comparative cross sectional study was carried out with healthy controls (n = 99) and patients who had undergone PR (n = 64) or TR (n = 12) of the large bowel. Participants consumed a standard (720 kcal) breakfast meal at 0830 (t = 0) h followed by lactulose (15 g) and a buffet lunch (t = 210 min). Participants rated the subjective feelings of hunger at t = -30, 0, 30, 60, 120, and 180 min...
August 2016: Obesity
Christine Ma-Kellams, Jennifer Lerner
Cultivating successful personal and professional relationships requires the ability to accurately infer the feelings of others-that is, to be empathically accurate. Some are better at this than others, a difference which may be explained in part by mode of thought. Specifically, empathically accurate people may tend to rely more on intuitive rather than systematic thought when perceiving others. Or it may be the reverse: systematic thought may increase empathic accuracy. To determine which view is supported by the evidence, we conducted 4 studies examining relations between mode of thought (intuitive vs...
July 21, 2016: Journal of Personality and Social Psychology
Gunnel Hänsel Petersson, Sigvard Åkerman, Per-Erik Isberg, Dan Ericson
BACKGROUND: Predicting future risk for oral diseases, treatment need and prognosis are tasks performed daily in clinical practice. A large variety of methods have been reported, ranging from clinical judgement or "gut feeling" or even patient interviewing, to complex assessments of combinations of known risk factors. In clinical practice, there is an ongoing continuous search for less complicated and more valid tools for risk assessment. There is also a lack of knowledge how different common methods relates to one another...
2016: BMC Oral Health
Seung Han Kim, Hoon Jai Chun, Hyuk Soon Choi, Eun Sun Kim, Bora Keum, Yoon Tae Jeen
Endoscopic bariatric therapy may be a useful alternative to pharmacological treatment for obesity, and it provides greater efficacy with lower risks than do conventional surgical procedures. Among the various endoscopic treatments for obesity, the intragastric balloon is associated with significant efficacy in body weight reduction and relief of comorbid disease symptoms. Anatomically, this treatment is based on gastric space-occupying effects that increase the feeling of satiety and may also affect gut neuroendocrine signaling...
June 28, 2016: World Journal of Gastroenterology: WJG
Herbert Tilg
No abstract text is available yet for this article.
June 23, 2016: New England Journal of Medicine
Walter H Moos, Douglas V Faller, David N Harpp, Iphigenia Kanara, Julie Pernokas, Whitney R Powers, Kosta Steliou
In the past century, noncommunicable diseases have surpassed infectious diseases as the principal cause of sickness and death, worldwide. Trillions of commensal microbes live in and on our body, and constitute the human microbiome. The vast majority of these microorganisms are maternally derived and live in the gut, where they perform functions essential to our health and survival, including: digesting food, activating certain drugs, producing short-chain fatty acids (which help to modulate gene expression by inhibiting the deacetylation of histone proteins), generating anti-inflammatory substances, and playing a fundamental role in the induction, training, and function of our immune system...
2016: BioResearch Open Access
Akito Kato-Kataoka, Kensei Nishida, Mai Takada, Mitsuhisa Kawai, Hiroko Kikuchi-Hayakawa, Kazunori Suda, Hiroshi Ishikawa, Yusuke Gondo, Kensuke Shimizu, Takahiro Matsuki, Akira Kushiro, Ryoutaro Hoshi, Osamu Watanabe, Tomoki Igarashi, Kouji Miyazaki, Yuki Kuwano, Kazuhito Rokutan
UNLABELLED: Stress-induced abdominal dysfunction is an attractive target for probiotics. To investigate the effects of the probiotic Lactobacillus casei strain Shirota on abdominal dysfunction, a double-blind, placebo-controlled trial was conducted with healthy medical students undertaking an authorized nationwide examination for academic advancement. For 8 weeks, until the day before the examination, 23 and 24 subjects consumed an L. casei strain Shirota-fermented milk and a placebo milk daily, respectively...
June 15, 2016: Applied and Environmental Microbiology
Majid Mojibian, Maria M Glavas, Timothy J Kieffer
The gut epithelium's large surface area, its direct exposure to ingested nutrients, its vast stem cell population and its immunotolerogenic environment make it an excellent candidate for therapeutic cells to treat diabetes. Thus, several attempts have been made to coax immature gut cells to differentiate into insulin-producing cells by altering the expression patterns of specific transcription factors. Furthermore, because of similarities in enteroendocrine and pancreatic endocrine cell differentiation pathways, other approaches have used genetically engineered enteroendocrine cells to produce insulin in addition to their endogenous secreted hormones...
April 2016: Journal of Diabetes Investigation
H Bart van der Worp
Guidelines for the management of non-variceal upper gastrointestinal haemorrhage recommend restarting anticoagulant therapy after treatment of the haemorrhage in patients with an indication for anticoagulation, such as atrial fibrillation. This recommendation is based on findings in retrospective observational studies, and probably also on common sense: if the cause of the haemorrhage has been treated, the chance of a life-threatening second gastrointestinal haemorrhage when anticoagulation is restarted is likely to be smaller than the chance of a serious thromboembolic complication if anticoagulation is stopped indefinitely...
2016: Nederlands Tijdschrift Voor Geneeskunde
Peter J Morris
No abstract text is available yet for this article.
May 2016: North Carolina Medical Journal
Tamara Zietek, Eva Rath
Chronic diseases, such as obesity and diabetes, cardiovascular, and inflammatory bowel diseases (IBD) share common features in their pathology. Metabolic disorders exhibit strong inflammatory underpinnings and vice versa, inflammation is associated with metabolic alterations. Next to cytokines and cellular stress pathways, such as the unfolded protein response (UPR), alterations in the enteroendocrine system are intersections of various pathologies. Enteroendocrine cells (EEC) have been studied extensively for their ability to regulate gastrointestinal motility, secretion, and insulin release by release of peptide hormones...
2016: Frontiers in Immunology
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