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https://www.readbyqxmd.com/read/29791425/-endoscopic-submucosal-dissection-of-a-transpyloric-early-gastric-c%C3%A3-ncer-a-case-report-and-literature-review
#1
Juan Antonio Chirinos Vega, César García Delgado, Alfonso Delgado Vergara
The endoscopic sumucosal disection (ESD) is an advanced endoscopic technique that achieves the curative resection of superficial neoplasms of the gastrointestinal tract, getting block exeresis with margins free of neoplasia avoiding surgery. However, tumors located in the esophagogastric junction, or pylorus, are technically more complex to resect by ESD. When a neoplasm settles in the pylorus, the anatomical characteristics of this region can affect the adequate assessment of the margins and the performance of the procedure...
January 2018: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/29790161/time-after-seawater-transfer-influences-immune-cell-abundance-and-responses-to-sav3-infection-in-atlantic-salmon
#2
J Jarungsriapisit, L J Moore, I U Fiksdal, H Bjørgen, A Tangerås, B Köllner, E O Koppang, S Patel
Pancreas disease (PD) caused by salmonid alphavirus (SAV) severely affects salmonid aquaculture during the seawater phase. To characterize immune cells in target tissues for SAV infection, heart, pancreas and pyloric caeca were analysed from two groups of fish adapted to seawater for 2 and 9 weeks. The sections were scored for the relative abundance of cells expressing MHC class II, IgM, CD3, CD8 or neutrophil/granulocyte markers using immuno-histochemical techniques. In general, necrosis of tissue was more severe in fish infected at 2 weeks post-seawater transfer (wpt) compared with those infected at 9 wpt...
May 23, 2018: Journal of Fish Diseases
https://www.readbyqxmd.com/read/29778241/dual-autonomic-inhibitory-action-of-central-apelin-on-gastric-motor-functions-in-rats
#3
Mehmet Bülbül, Osman Sinen
Centrally administered apelin has been shown to inhibit gastric emptying (GE) in rodents, however, the relevant mechanism has been investigated incompletely. Using male Wistar rats, we investigated the efferent pathways involved in gastroinhibitory action of central apelin. Stereotaxic intracerebroventricular (icv) cannulation, subdiaphragmatic vagotomy (VGX) and/or celiac ganglionectomy (CGX) were performed 7 days prior to the experiments. Apelin-13 was administered (30 nmol, icv) 90 min prior to GE measurement...
July 2018: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/29777447/integra-%C3%A2-dermal-regeneration-template-and-split-thickness-skin-grafting-a-therapy-approach-to-correct-aplasia-cutis-congenita-and-epidermolysis-bullosa-in-carmi-syndrome
#4
Julian Trah, Christina Has, Ingrid Hausser, Heinz Kutzner, Konrad Reinshagen, Ingo Königs
The association of junctional epidermolysis bullosa with pyloric atresia (JEB-PA) and aplasia cutis congenita (ACC) was described by El Shafie et al. (J Pediatr Surg 14(4):446-449, 1979) and Carmi et al. (Am J Med Genet 11:319-328, 1982). Most patients die in the first weeks of life, and no curative treatment options are available so far. We describe a patient with JEB-PA and ACC (OMIM # 226730) who was treated for extensive areas of ACC by Integra® -Dermal Regeneration Template and split-thickness skin grafting (STSG)...
May 18, 2018: Dermatology and Therapy
https://www.readbyqxmd.com/read/29773763/initial-experience-with-endoscopic-sleeve-gastroplasty-in-poland
#5
Aleksander Sowier, Przemysław Pyda, Anna-Maria Borucka, Sebastian Sowier, Jacek Białecki, Joanna Kapturzak, Stanisław Wójtowicz
INTRODUCTION: Obesity is becoming one of the major public health problems. Bariatric procedures are considered the most effective methods of treating this condition but they are costly and entail a high risk of complications. Thus, there is a need to look for better bariatric treatment solutions. One of the newest, highly promising bariatric methods is endoscopic sleeve gastroplasty (ESG), which is comparably effective to other bariatric procedures in terms of weight loss but at the same time it is much less invasive...
April 30, 2018: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/29755007/structure-of-the-alimentary-tract-in-the-atlantic-mudskipper-periophthalmus-barbarus-gobiidae-oxudercinae-anatomical-histological-and-ultrastructural-studies
#6
Katarzyna Wołczuk, Maciej Ostrowski, Agnieszka Ostrowska, Teresa Napiórkowska
The alimentary tract of oxudercine gobies is characterized by a lack of an anatomically distinct stomach, owing to which they are classified as stomachless. Since the environment, food requirements, and feeding habits have a significant impact on the anatomy of the alimentary tract of fish, it was assumed that predominantly carnivorous, semi-terrestrial mudskippers would have a stomach. In order to verify this hypothesis, anatomical, histological, histochemical and ultrastructural analysis of the alimentary tract of the Atlantic mudskipper Periophthalmus barbarus was performed...
April 26, 2018: Zoology: Analysis of Complex Systems, ZACS
https://www.readbyqxmd.com/read/29754879/congenital-pyloric-atresia-nine-new-cases-single-center-experience-of-the-long-term-follow-up-and-the-lessons-learnt-over-a-decade
#7
Monal Kansra, V Shankar Raman, Kamal Kishore, Sanat Khanna, Bipin Puri, Abhishek Sharma
BACKGROUND: Congenital pyloric atresia (CPA) is a rare anomaly with an incidence of 1 in 100,000 live births. Depending on the type of anomaly patients can either present in the neonatal period or later in life with subtle nonspecific signs and symptoms. We present our institute's experience in handling these cases over the last decade and highlight lessons learnt. MATERIALS AND METHODS: We retrospectively reviewed records of patients diagnosed with CPA and managed at our centre between Jan 2006 to June 2016...
April 14, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29747051/immune-modulation-of-two-batf3-paralogues-in-rainbow-trout-oncorhynchus-mykiss
#8
Jun Wang, Min Liu, Yang Wu, Sohye Yoon, Abdo Alnabulsi, Fuguo Liu, Clara Fernández-Álvarez, Tiehui Wang, Jason W Holland, Chris J Secombes, Jun Zou
Basic leucine zipper transcription factor ATF-like (BATF) -3 is a member of the activator protein 1 (AP‑1) family of transcription factors and is known to play a vital role in regulating differentiation of antigen-presenting cells in mammals. In this study, two BATF3 homologues (termed BATF3a and BATF3b) have been identified in rainbow trout (Oncorhynchus mykiss). Both genes were constitutively expressed in tissues, with particularly high levels of BATF3a in spleen, liver, pyloric caecae and head kidney. BATF3a was also more highly induced by PAMPs and cytokines in cultured cells, with type II IFN a particularly potent inducer...
May 7, 2018: Molecular Immunology
https://www.readbyqxmd.com/read/29729058/a-case-of-pyloric-gland-adenoma-accompanied-by-a-component-of-foveolar-epithelial-type-adenoma-within-the-lesion
#9
Keiichiro Nakajo, Yasuhiro Oono, Takeshi Kuwata
An 80-year-old woman found to have a gastric tumor by endoscopy was referred to our hospital for further examination and treatment. Helicobacter pylori eradication therapy was successfully performed 10 years ago. Conventional endoscopy revealed a 20-mm flat elevated lesion in the greater curvature of the middle gastric body. (Fig. 1a). Magnifying endoscopy with narrow band imaging (M-NBI) revealed an irregular microvascular architecture, including closed-loop vessels with repeated irregular anastomoses (Fig...
May 5, 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29728381/crown-of-thorns-sea-star-acanthaster-cf-solaris-have-tissue-characteristic-microbiomes-with-potential-roles-in-health-and-reproduction
#10
Lone Høj, Natalie Levy, Brett K Baillie, Peta L Clode, Raphael C Strohmaier, Nachshon Siboni, Nicole S Webster, Sven Uthicke, David G Bourne
Outbreaks of coral-eating crown-of-thorns sea stars (CoTS; Acanthaster spp. complex) cause substantial coral loss, hence there is considerable interest in developing prevention and control strategies. We characterised the microbiome of captive CoTS and assessed whether dysbiosis was evident in sea stars during a disease event. Most tissue types had a distinct microbiome. The exception was female gonads, which were highly variable amongst individuals. Male gonads were dominated (>97% of reads) by a single Mollicutes -related OTU...
May 4, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29709494/pyloric-sphincter-characteristics-using-endoflip-%C3%A2-in-gastroparesis
#11
M Saadi, D Yu, Z Malik, H P Parkman, R Schey
INTRODUCTION AND AIMS: Pyloric sphincter abnormalities may be detected in gastroparesis. Botulinum toxin A (BoNT/A) injection into the pylorus has been used to treat gastroparesis with varying results. The aim of the present article was to assess whether pyloric sphincter characteristics using the endoscopic functional lumen imaging probe (EndoFLIP® ) with impedance planimetry in patients with gastroparesis correlated with symptoms, gastric emptying, and therapeutic response to pyloric sphincter BoNT/A injection...
April 27, 2018: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/29692530/primary-presentation-of-jeune-s-syndrome-as-gastric-motility-disorder-in-an-infant-a-case-report
#12
Amit Katyan, Shabnam Bhandari Grover, Heena Rajani, Deepak Bagga, Neha Antil
We report a case of a 4-week-old female neonate with Jeune's asphyxiating thoracic dystrophy (JATD) and coexistent situs anomaly, primarily presenting as gastric motility disorder. The child presented with abdominal distension and nonbilious vomiting since birth with failure to thrive. However, skeletal survey revealed JATD. Upper gastrointestinal contrast study showed situs inversus with delayed gastric emptying. Pyloric biopsy and intraoperative antro-duodenal manometry confirmed association of gastric motility disorder...
January 2018: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/29689854/description-and-dna-barcoding-of-lycenchelys-lenzeni-a-new-species-of-eelpout-perciformes-zoarcidae-from-the-deep-sea-off-the-kuril-archipelago
#13
Ralf Thiel, Thomas Knebelsberger, Irina Eidus
A new species of eelpout genus Lycenchelys Gill, 1884 is described based on seven specimens caught at a depth of about 2350 m in the Bussol Strait, southwest of the Kuril Island Simushir. The species differs from its congeners in the following combination of characters: vertebrae 26-28 + 100-102 = 126-130; interorbital and occipital pores absent; postorbital pores 3-4; suborbital pores 7 (rarely 6); preoperculomandibular pores 4 + 4; gill rakers 11-16; dorsal fin rays 118-122; anal fin rays 105-108; pelvic fin rays 2; middle and lower ray tips of pectoral fin very slightly exserted; lateral line double with mediolateral and ventral branches; pyloric caeca not developed...
January 9, 2018: Zootaxa
https://www.readbyqxmd.com/read/29687294/endoscopic-therapies-for-gastroparesis
#14
REVIEW
Andrew Su, Jeffrey L Conklin, Alireza Sedarat
PURPOSE OF REVIEW: Gastroparesis remains a difficult-to-treat disease with limited therapeutic options. Though patients often have a common syndrome of stereotypic symptoms, the underlying pathophysiology is heterogeneous, often leading to variable treatment responses. Due to limitations in medical and surgical therapies, endoscopic options have been increasingly explored. These options can be broadly categorized into pyloric-directed therapy, non-pyloric-directed therapy, and nutritional support...
April 23, 2018: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/29686790/adult-idiopathic-hypertrophic-pyloric-stenosis-a-common-presentation-with-an-uncommon-diagnosis
#15
Syed Moin Hassan, Ateeq Mubarik, Salman Muddassir, Furqan Haq
Background and Objectives: Adult Idiopathic hypertrophic pyloric stenosis (AIHPS) is a rare but well-defined entity in adults with only 200-300 cases reported so far in the literature.We describe a case of AIHPS and the relevant literature review. Methods and Results: The patient presented with acute onset upper abdominal pain associated with nausea, vomiting, foul-smelling black tarry stools, and anorexia. On the Esophagogastroduodenoscopy (EGD), pylorus demonstrated a unique "cervix sign." The patient had multiple endoscopic dilations with minimal relief...
2018: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29669762/yap-taz-initiates-gastric-tumorigenesis-via-upregulation-of-myc
#16
Wonyoung Choi, Jeongsik Kim, Jaeoh Park, Da-Hye Lee, Daehee Hwang, Jeong-Hwan Kim, Hassan Ashktorab, Duane T Smoot, Seon-Young Kim, Chan Choi, Gou Young Koh, Dae-Sik Lim
YAP and TAZ play oncogenic roles in various organs, but the role of YAP/TAZ in gastric cancer remains unclear. Here we show that YAP/TAZ activation initiates gastric tumorigenesis in vivo and verify its significance in human gastric cancer. In mice, YAP/TAZ activation in the pyloric stem cell led to step-wise tumorigenesis. RNA sequencing identified MYC as a decisive target of YAP, which controls MYC at transcriptional and post-transcriptional levels. These mechanisms tightly regulated MYC in homeostatic conditions, but YAP activation altered this balance by impeding miRNA processing, causing a shift towards MYC upregulation...
April 18, 2018: Cancer Research
https://www.readbyqxmd.com/read/29667709/the-outlet-patch-gastric-heterotopia-of-the-colo-rectum-and-anus
#17
Abul Ala Syed Rifat Mannan, Michael Vieth, Armen Khararjian, Binny Khandakar, Dora Lam-Himlin, David Heydt, Feriyl Bhaijee, Henry J Venbrux, Kathleen Byrnes, Lysandra Voltaggio, Norman Barker, Songyang Yuan, Elizabeth Montgomery
AIMS: Gastric heterotopia (GH) has been described throughout the gastrointestinal tract. However, the colorectal region is an extremely rare location for it. We describe the clinicopathologic features of GH of the colon, rectum, and anus. METHODS AND RESULTS: We identified 33 cases in 20 males and 13 females (median age 54 years; range, 4 months to 73 years). Sites included the rectum (N=26), anus (N=4), ileocecal junction (N=1), ascending colon (N=1) and descending colon (N=1)...
April 18, 2018: Histopathology
https://www.readbyqxmd.com/read/29667092/intraoperative-pyloric-interventions-during-oesophagectomy-a-multicentre-study
#18
Salvatore Marchese, Yassar A Qureshi, Shazia P Hafiz, Khaled Dawas, Paul Turner, M Muntzer Mughal, Borzoueh Mohammadi
BACKGROUND: Denervation of the pylorus after oesophagectomy is considered the principal factor responsible for delayed gastric emptying. Several studies have attempted to delineate whether surgical or chemical management of the pylorus during oesophagectomy is of benefit, but with conflicting results. The aim of this multicentre study was to assess whether there was any difference in outcomes between different approaches to management of the pylorus. METHODS: A prospectively maintained database was used to identify patients who underwent oesophagectomy for malignancy...
April 17, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29666402/expression-of-kk-lc-1-a-cancer-testis-antigen-at-non-tumour-sites-of-the-stomach-carrying-a-tumour
#19
Takashi Fukuyama, Nobue Futawatari, Rui Yamamura, Taiga Yamazaki, Yoshinobu Ichiki, Akira Ema, Hideki Ushiku, Yatsushi Nishi, Yoshihito Takahashi, Toshikazu Otsuka, Hitoshi Yamazaki, Wasaburo Koizumi, Kosei Yasumoto, Noritada Kobayashi
Kita-Kyushu lung cancer antigen-1 (KK-LC-1) is a cancer/testis antigen (CTA) and predominant target for cancer immunotherapy. Our previous study indicated that KK-LC-1 was expressed in 82% of gastric cancers, and also in 79% of early stage of gastric cancers, with a correlation to Helicobacter pylori (H. pylori) infection. In addition, we found that KK-LC-1 was occasionally expressed at non-tumour sites of stomachs carrying tumours. Here, we investigated the characteristics of KK-LC-1 expression at non-tumour sites and the clinical utility of these phenomena...
April 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29663766/kirurgisk-behandling-av-pylorusstenose
#20
Kaja Mørk, Hans Skari, Ole Schistad, Pål Aksel Næss
BACKGROUND: Pyloric stenosis is one of the most common surgical conditions in infants. This study aims to investigate diagnostics and results of surgical treatment for pyloric stenosis at Oslo University Hospital Ullevål. MATERIAL AND METHOD: A retrospective review of patient records for those undergoing surgery for pyloric stenosis in the period 2004-2016 was conducted. Preoperative symptoms and findings, diagnostics, treatment and postoperative results were recorded...
April 17, 2018: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
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