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https://www.readbyqxmd.com/read/29925115/-return-to-work-and-stay-at-work-the-question-of-successful-operational-integration-management
#1
Heike Ohlbrecht, Carsten Detka, Susanne Kuczyk, Bianca Lange
OBJECTIVE: The study focuses on the question of how the design of operational integration management (OIM) can be optimized, especially in small and medium-sized enterprises (SMEs), and how previous experience with operational integration management can be used to develop preventive measures to ensure employability. METHODS: The study follows a multi-perspective qualitative research design. It focused on the survey of 40 retrospective interviews with employees who have undergone different variants of the OIM...
June 2018: Die Rehabilitation
https://www.readbyqxmd.com/read/29925098/design-and-testing-of-a-smartphone-application-for-real-time-self-tracking-diabetes-self-management-behaviors
#2
Danielle Groat, Hiral Soni, Maria Adela Grando, Bithika Thompson, David Kaufman, Curtiss B Cook
BACKGROUND:  Type 1 diabetes (T1D) care requires multiple daily self-management behaviors (SMBs). Preliminary studies on SMBs rely mainly on self-reported survey and interview data. There is little information on adult T1D SMBs, along with corresponding compensation techniques (CTs), gathered in real-time. OBJECTIVE:  The article aims to use a patient-centered approach to design iDECIDE, a smartphone application that gathers daily diabetes SMBs and CTs related to meal and alcohol intake and exercise in real-time, and contrast patients' actual behaviors against those self-reported with the app...
April 2018: Applied Clinical Informatics
https://www.readbyqxmd.com/read/29925092/bilateral-radial-agenesis-in-a-cat-treated-with-bilateral-ulnocarpal-arthrodesis
#3
Alla Bezhentseva, Harpreet Singh, Randy J Boudrieau
OBJECTIVE:  This article describes corrective antebrachiocarpal re-alignment and arthrodesis for bilateral radial hemimelia (radial agenesis) in an 8-month-old domestic short-haired cat. METHODS:  Bilateral forelimb deformity of ulnocarpal varus with complete luxation and rotation of the antebrachiocarpal joint spaces, and joint contracture, was observed. Several carpal bones and metacarpal bones I and II and their associated phalanges were absent. Abnormal ambulation and weight bearing on the dorsolateral part of the manus were present...
June 20, 2018: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/29925090/erratum-to-a-double-blind-randomized-placebo-controlled-trial-of-17-alpha-hydroxyprogesterone-caproate-in-the-management-of-preterm-premature-rupture-of-membranes
#4
Elizabeth S Langen, Anita Sit, Katie Sherwin, Deirdre J Lyell, Yair J Blumenfeld, Yasser Y El-Sayed
No abstract text is available yet for this article.
June 20, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29925088/measles-high-school-vaccination-program-2014-2015-online-survey-of-parents-in-nsw-australia
#5
Sonya Nicholl, Holly Seale, Sue Campbell-Lloyd
BACKGROUND: In 2014, a high school-based measles supplementary immunisation activity (SIA) took place in New South Wales (NSW), Australia, in response to a large number of adolescents being identified as undervaccinated or unvaccinated against measles. The program focused on areas of NSW where previous measles outbreaks had occurred and where large numbers of undervaccinated adolescents lived. More than 11 000 students were vaccinated in 2014, and the program continued in 2015, when more than 4000 students in Years 11 and 12 were vaccinated...
June 14, 2018: Public Health Research & Practice
https://www.readbyqxmd.com/read/29924972/holy-immune-tolerance-batman
#6
Haley E Randolph, Luis B Barreiro
Bats are reservoir hosts of numerous viruses that cause severe pathology in humans. How bats cope with such pathogens remains elusive. In a recent issue of Cell, Pavlovich et al. (2018) describe several key adaptations in innate immune-related genes that suggest that the Egyptian rousette fruit bat relies on immune tolerance mechanisms to manage viral infections.
June 19, 2018: Immunity
https://www.readbyqxmd.com/read/29924966/a-proteomic-variant-approach-provara-for-personalized-medicine-of-inherited-and-somatic-disease
#7
DarrenM Hutt, Salvatore Loguercio, Alexandre Rosa Campos, William E Balch
The advent of precision medicine for genetic diseases has been hampered by the large number of variants that cause familial and somatic disease, a complexity that is further confounded by the impact of genetic modifiers. To begin to understand differences in onset, progression and therapeutic response that exist among disease-causing variants, we present the proteomic variant approach (ProVarA), a proteomic method that integrates mass spectrometry with genomic tools to dissect the etiology of disease. To illustrate its value, we examined the impact of variation in cystic fibrosis (CF), where 2025 disease-associated mutations in the CF transmembrane conductance regulator (CFTR) gene have been annotated and where individual genotypes exhibit phenotypic heterogeneity and response to therapeutic intervention...
June 17, 2018: Journal of Molecular Biology
https://www.readbyqxmd.com/read/29924904/neuroinformatics-and-computational-modelling-as-complementary-tools-for-neurotoxicology-studies
#8
Marja-Leena Linne
Neuroinformatics is an area of science that aims to integrate neuroscience data and develop modern computational tools to increase our understanding of the functions of the nervous system in health and disease. Neuroinformatics tools include, among others, databases for storing and sharing data, repositories for managing documents and source code, and software tools for analysing, modelling and simulating signals and images. This MiniReview aims to present the state-of-the-art in neuroinformatics and computational in silico modelling of neurobiological processes and neuroscientific phenomena as well as to discuss the use of in silico models in neurotoxicology research...
June 20, 2018: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29924887/exploring-the-potential-for-multivariate-fragility-representations-to-alter-flood-risk-estimates
#9
Robert A Jane, David J Simmonds, Ben P Gouldby, Jonathan D Simm, Luciana Dalla Valle, Alison C Raby
In flood risk analysis, limitations in the multivariate statistical models adopted to model the hydraulic load have restricted the probability of a defense suffering structural failure to be expressed conditionally on a single hydraulic loading variable. This is an issue at the coastal level where multiple loadings act on defenses with the exact combination of loadings dictating their failure probabilities. Recently, a methodology containing a multivariate statistical model with the flexibility to robustly capture the dependence structure between the individual loadings was used to derive extreme nearshore loading conditions...
June 20, 2018: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/29924878/chiari-i-malformation-and-basilar-invagination-in-fibrous-dysplasia-prevalence-mechanisms-and-clinical-implications
#10
Kristen S Pan, John D Heiss, Sydney M Brown, Michael T Collins, Alison M Boyce
Fibrous dysplasia (FD) is a mosaic disorder of benign fibro-osseous lesions, which may be associated with extraskeletal features as part of McCune-Albright syndrome (MAS). Cranial base abnormalities, including Chiari I malformation (CM1), in which the cerebellum extends below the foramen magnum, and secondary basilar invagination (BI), in which the odontoid prolapses into the posterior cranial fossa, are potentially serious complications of metabolic bone disorders. The purpose of this study was to determine the prevalence, natural history, and risk factors for CM1 and BI in patients with FD/MAS, and to determine mechanisms of cranial base deformities...
June 20, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29924865/the-organizational-attributes-of-hiv-care-delivery-models-in-canada-a-cross-sectional-study
#11
Claire E Kendall, Esther Susanna Shoemaker, Lisa Boucher, Danielle E Rolfe, Lois Crowe, Marissa Becker, Shabnam Asghari, Sean B Rourke, Ron Rosenes, Christine Bibeau, Philip Lundrigan, Clare Liddy
HIV treatment in Canada has rapidly progressed with the advent of new drug therapies and approaches to care. With this evolution, there is increasing interest in Canada in understanding the current delivery of HIV care, specifically where care is delivered, how, and by whom, to inform the design of care models required to meet the evolving needs of the population. We conducted a cross-sectional survey of Canadian care settings identified as delivering HIV care between June 2015 and January 2016. Given known potential differences in delivery approaches, we stratified settings as primary care or specialist settings, and described their structure, geographic location, populations served, health human resources, technological resources, and available clinical services...
2018: PloS One
https://www.readbyqxmd.com/read/29924846/prevalence-of-diabetic-retinopathy-and-diabetic-macular-edema-in-a-primary-care-based-teleophthalmology-program-for-american-indians-and-alaskan-natives
#12
Sven-Erik Bursell, Stephanie J Fonda, Drew G Lewis, Mark B Horton
BACKGROUND: Diabetes and its complications are more common in American Indians and Alaska Natives (AI/AN) than other US racial/ethnic populations. Prior reports of diabetic retinopathy (DR) prevalence in AI/AN are dated, and research on diabetic macular edema (DME) is limited. This study characterizes the recent prevalence of DR and DME in AI/AN using primary care-based teleophthalmology surveillance. METHODS: This is a multi-site, clinic-based, cross-sectional study of DR and DME...
2018: PloS One
https://www.readbyqxmd.com/read/29924839/fungal-communities-associated-with-almond-throughout-crop-development-implications-for-aflatoxin-biocontrol-management-in-california
#13
Alejandro Ortega-Beltran, Juan Moral, Ryan D Puckett, David P Morgan, Peter J Cotty, Themis J Michailides
Interactions between pathogenic and nonpathogenic fungal species in the tree canopy are complex and can determine if disease will manifest in the plant and in other organisms such as honey bees. Seasonal dynamics of fungi were studied in an almond orchard in California where experimental release of the atoxigenic biopesticide Aspergillus flavus AF36 to displace toxigenic Aspergillus strains has been conducted for five years. The presence of the vegetative compatibility group (VCG) YV36, to which AF36 belongs, in the blossoms, and the honey bees that attend these blossoms, was assessed...
2018: PloS One
https://www.readbyqxmd.com/read/29924829/a-stream-classification-system-to-explore-the-physical-habitat-diversity-and-anthropogenic-impacts-in-riverscapes-of-the-eastern-united-states
#14
Ryan A McManamay, Matthew J Troia, Christopher R DeRolph, Arlene Olivero Sheldon, Analie R Barnett, Shih-Chieh Kao, Mark G Anderson
Describing the physical habitat diversity of stream types is important for understanding stream ecosystem complexity, but also prioritizing management of stream ecosystems, especially those that are rare. We developed a stream classification system of six physical habitat layers (size, gradient, hydrology, temperature, valley confinement, and substrate) for approximately 1 million stream reaches within the Eastern United States in order to conduct an inventory of different types of streams and examine stream diversity...
2018: PloS One
https://www.readbyqxmd.com/read/29924826/investigation-of-ciguatoxins-in-invasive-lionfish-from-the-greater-caribbean-region-implications-for-fishery-development
#15
D Ransom Hardison, William C Holland, H Taiana Darius, Mireille Chinain, Patricia A Tester, Damian Shea, Alex K Bogdanoff, James A Morris, Harold A Flores Quintana, Christopher R Loeffler, Dayne Buddo, R Wayne Litaker
Lionfish, native to reef ecosystems of the tropical and sub-tropical Indo-Pacific, were introduced to Florida waters in the 1980s, and have spread rapidly throughout the northwestern Atlantic, Caribbean Sea and the Gulf of Mexico. These invasive, carnivorous fish significantly reduce other fish and benthic invertebrate biomass, fish recruitment, and species richness in reef ecosystems. Fisheries resource managers have proposed the establishment of a commercial fishery to reduce lionfish populations and mitigate adverse effects on reef communities...
2018: PloS One
https://www.readbyqxmd.com/read/29924825/second-harmonic-generation-microscopy-provides-accurate-automated-staging-of-liver-fibrosis-in-patients-with-non-alcoholic-fatty-liver-disease
#16
Pik Eu Chang, George Boon Bee Goh, Wei Qiang Leow, Liang Shen, Kiat Hon Lim, Chee Kiat Tan
BACKGROUND: Assessment of severity of liver fibrosis is essential in the management of non-alcoholic fatty liver disease (NAFLD). Second Harmonic Generation (SHG) microscopy is a novel optical tissue imaging system that provides automated quantification of fibrosis based on unique architectural features of collagen. This study aims to develop and validate a SHG-based index for automated staging of liver fibrosis in patients with NAFLD. METHODS: SHG microscopy was performed on archived liver biopsy specimens from 83 patients with NAFLD...
2018: PloS One
https://www.readbyqxmd.com/read/29924809/the-added-value-of-implicit-motives-for-management-research-development-and-first-validation-of-a-brief-implicit-association-test-biat-for-the-measurement-of-implicit-motives
#17
Hendrik Slabbinck, Arjen van Witteloostuijn, Julie Hermans, Johanna Vanderstraeten, Marcus Dejardin, Jacqueline Brassey, Dendi Ramdani
Many Management (sub-)disciplines, from Organizational Behavior and Marketing to Accounting and Strategy, are interested in antecedents and consequences of individual attitudes and traits. A key aspect of personality profiles are explicit and implicit motives. Yet, Management scholars mainly focus on explicit motives, with limited attention to implicit motives. We argue that this state of affairs probably came into being because current Management researchers mainly rely on implicit motive measures that are either difficult to apply or to develop, hampering researchers from applying implicit motive measures...
2018: PloS One
https://www.readbyqxmd.com/read/29924797/survival-and-nutritional-status-of-children-with-severe-acute-malnutrition-six-months-post-discharge-from-outpatient-treatment-in-jigawa-state-nigeria
#18
Collins John, Udochukwu Diala, Ruth Adah, Luret Lar, Esther Awazzi Envuladu, Idris Adedeji, Kazeem Lasisi, Oluseyi Olusunde, Femi James, Halima Abdu
BACKGROUND: The Outpatient Therapeutic Program (OTP) for treatment brings the management of Severe Acute Malnutrition (SAM) closer to the community. Many lives have been saved through this approach, but little data exists on the outcome of the children after discharge from such programmes. This study was aimed to determine the survival and nutritional status of children at six months after discharge from OTP for SAM. METHODOLOGY: This was a prospective study of children with SAM admitted into 10 OTPs in two local government areas of Jigawa state from June 2016 to July 2016...
2018: PloS One
https://www.readbyqxmd.com/read/29924791/-algorithm-of-treatment-policy-for-a-femoral-artery-false-aneurysm
#19
A A Fokin, K A Kireev
The purpose of the study was to elaborate an algorithm of treatment policy for post-puncture false aneurysms of the femoral artery (FAFA). The study was performed on the basis of the clinical material over 2014-2017 at the Regional Vascular Centre whose specialists have since 2017 been using the femoral arterial approach (FAA) only if the radial arteries are inaccessible for puncture or for inserting the endovascular tools and appliances. The obtained findings demonstrated that the number of coronary interventions performed with the use of the femoral arterial approach in patients presenting with acute coronary syndrome decreased from a total of 758 (100...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29924781/-therapeutic-policy-in-stenosis-of-the-internal-carotid-artery-combined-with-intracranial-vascular-malformation
#20
A I Khripun, A D Priamikov, A B Mironkov, L D Gulina
Presented herein is the world experience of surgical treatment and various tactical approaches in a combined lesion of the extracranial and intracranial portions of the internal carotid artery (ICA): a combination of its stenosis or occlusion with vascular malformation of the brain (a cerebral aneurysm, pathological anastomoses, arteriovenous malformations). Also pointed out is the prevalence of the pathology involved, followed by describing various types of surgical policy in this condition: staged and simultaneous interventions, endovascular and standard operative auxiliary techniques...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
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