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https://www.readbyqxmd.com/read/28732395/microalgae-bacteria-models-evolution-from-microalgae-steady-state-to-integrated-microalgae-bacteria-wastewater-treatment-models-a-comparative-review
#1
REVIEW
Alessandro Solimeno, Joan García
The search for environmentally neutral alternative fuels had revived the interest for microalgae-bacteria wastewater treatment systems. The potential achieving of bioproducts from microalgae biomass has also greatly contributed. The reactions that occur in these systems are complex, and the degree of scientific knowledge is still scarce compared to that of conventional bacteria wastewater treatments. Mathematical models offer a great opportunity to study the simultaneous effect of the multiple factors affecting microalgae and bacteria, thus allowing for the prediction of final biomass production, and contributing to the system design optimization in terms of operation and control...
July 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28732378/acetylation-and-deacetylation-in-cancer-stem-like-cells
#2
REVIEW
Na Liu, Shiqi Li, Nan Wu, Kin-Sang Cho
Cancer stem-like cell (CSC) model has been established to investigate the underlying mechanisms of tumor initiation and progression. The imbalance between acetylation and deacetylation of histone or non-histone proteins, one of the important epigenetic modification processes, is closely associated with a wide variety of diseases including cancer. Acetylation and deacetylation are involved in various stemness-related signal pathways and drive the regulation of self-renewal and differentiation in normal developmental processes...
July 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28732337/critical-review-of-soil-contamination-by-polybrominated-diphenyl-ethers-pbdes-and-novel-brominated-flame-retardants-nbfrs-concentrations-sources-and-congener-profiles
#3
REVIEW
Thomas J McGrath, Andrew S Ball, Bradley O Clarke
Polybrominated diphenyl ethers (PBDEs) have been used in a broad array of polymeric materials such as plastics, foams, resins and adhesives to inhibit the spread of fires since the 1970s. The widespread environmental contamination and well documented toxic effects of PBDEs have led to bans and voluntary withdrawals in many jurisdictions. Replacement novel brominated flame retardants (NBFRs) have, however, exhibited many of the same toxic characteristics as PBDEs and appear to share similar environmental fate...
July 18, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28732264/insights-into-plant-phosphate-sensing-and-signaling
#4
REVIEW
Byung-Kook Ham, Jieyu Chen, Yan Yan, William J Lucas
Phosphorus (P) is a macronutrient essential for plant growth, therefore, soil P level is critical to crop yield potential in agriculture. As Pi levels limit crop yield under many soil conditions, it is crucial to understand the mechanisms by which plants adapt to low-phosphate (Pi) soil conditions and interact with their soil microbiome to improve crop P use efficiency, in order to ensure global food security. Recent advances have been made towards achieving this goal through advancing our understanding of the plant's response to limiting Pi conditions to maintain P homeostasis...
July 18, 2017: Current Opinion in Biotechnology
https://www.readbyqxmd.com/read/28732254/going-down-the-tubes-impact-on-seizure-control-of-antiepileptic-medication-given-via-percutaneous-feeding-tubes
#5
REVIEW
Caryn Jory, Rohit Shankar, Katy Oak, Janina Oates, Mike Wilcock
BACKGROUND: Long-term feeding by percutaneous endoscopic gastrostomy tube (PEG) is uncommon but can present significant issues when both nutrition and medication have to be fed down the same tube. This is especially important in people with epilepsy where the dose and bioavailability of antiepileptic drugs are critical to maintain adequate seizure control. This group with long-term PEG tubes is particularly vulnerable and dependent on their carers to provide high standard of care. Indeed, approximately half of the people with long-term feeding tubes suffer from severe intellectual disability which requires careful coordination of all members of the multidisciplinary team...
July 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28732149/beware-of-the-origin-of-numbers-standard-scoring-of-the-sf-12-and-sf-36-summary-measures-distorts-measurement-and-score-interpretations
#6
Peter Hagell, Albert Westergren, Kristofer Årestedt
The 12-item Short Form Health Survey (SF-12) is a generic health rating scale developed to reproduce the Physical and Mental Component Summary scores (PCS and MCS, respectively) of a longer survey, the SF-36. The standard PCS/MCS scoring algorithm has been criticized because its expected dimensionality often lacks empirical support, scoring is based on the assumption that physical and mental health are uncorrelated, and because scores on physical health items influence MCS scores, and vice versa. In this paper, we review the standard PCS/MCS scoring algorithm for the SF-12 and consider alternative scoring procedures: the RAND-12 Health Status Inventory (HSI) and raw sum scores...
August 2017: Research in Nursing & Health
https://www.readbyqxmd.com/read/28731945/the-changing-paradigm-of-radiotherapy-in-the-elderly-population
#7
Myer Raphael Pfeffer, Philip Blumenfeld
There is increasing awareness of the special needs for care of the elderly cancer patient. Newer precise conformal radiotherapy techniques allow the safe delivery of higher doses of radiotherapy to the target tumor while reducing the dose to surrounding critical organs. This has led to a shortening of radiotherapy protocols for both curative and palliative indications. We review these novel techniques and protocols and the published clinical studies that include elderly patients treated with these techniques...
July 2017: Cancer Journal
https://www.readbyqxmd.com/read/28731924/clinical-trial-registry-use-in-anaesthesiology-systematic-reviews-a-cross-sectional-study-of-systematic-reviews-published-in-anaesthesiology-journals-and-the-cochrane-library
#8
Blake A Umberham, Byron N Detweiler, Matthew T Sims, Matt Vassar
BACKGROUND: Publication bias within systematic reviews may result in incorrect conclusions leading to inappropriate clinical decisions and a decreased quality of patient care. Searching clinical trial registries for unpublished studies is one possible solution to minimise publication bias. OBJECTIVES: To examine rates of clinical trial registry searches in systematic reviews published in respected anaesthesiology journals and whether these searches found trials (or data) eligible for inclusion; to compare rates of registry searches between published reviews and similar reviews within the Cochrane Anaesthesia, Critical and Emergency Care Group; to conduct trial registry searches for a subset of reviews, determining whether eligible studies were overlooked; to investigate whether reporting of results in completed anaesthesia trials on ClinicalTrials...
July 20, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28731874/novel-targets-for-anticoagulants-lacking-bleeding-risk
#9
Julia K Bickmann, Trevor Baglin, Joost C M Meijers, Thomas Renné
PURPOSE OF REVIEW: Arterial and venous thromboembolic diseases are associated with significant morbidity and mortality and present a major medical burden. Currently used anticoagulants for the prevention or treatment of thromboembolic events including heparins, vitamin K-antagonists and inhibitors of thrombin or factor Xa target enzymes of the coagulation cascade that are critical for fibrin formation. However, fibrin is also necessary for hemostatic mechanisms to terminate blood loss at injury sites...
July 20, 2017: Current Opinion in Hematology
https://www.readbyqxmd.com/read/28731847/the-colorful-world-of-extracellular-electron-shuttles
#10
Nathaniel R Glasser, Scott H Saunders, Dianne K Newman
Descriptions of the changeable, striking colors associated with secreted natural products date back well over a century. These molecules can serve as extracellular electron shuttles (EESs) that permit microbes to access substrates at a distance. In this review, we argue that the colorful world of EESs has been too long neglected. Rather than simply serving as a diagnostic attribute of a particular microbial strain, redox-active natural products likely play fundamental, underappreciated roles in the biology of their producers, particularly those that inhabit biofilms...
July 21, 2017: Annual Review of Microbiology
https://www.readbyqxmd.com/read/28731402/twenty-four-hour-emergency-intervention-versus-early-intervention-in-aneurysmal-subarachnoid-hemorrhage
#11
Joseph R Linzey, Craig Williamson, Venkatakrishna Rajajee, Kyle Sheehan, B Gregory Thompson, Aditya S Pandey
OBJECTIVE Recent observational data suggest that ultra-early treatment of ruptured aneurysms prevents rebleeding, thus improving clinical outcomes. However, advances in critical care management of patients with ruptured aneurysms may reduce the rate of rebleeding in comparison with earlier trials, such as the International Cooperative Study on the Timing of Aneurysm Surgery. The objective of the present study was to determine if an ultra-early aneurysm repair protocol will or will not significantly reduce the number of incidents of rebleeding following aneurysmal subarachnoid hemorrhage (SAH)...
July 21, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28731396/contralateral-posterior-interhemispheric-approach-to-deep-medial-parietooccipital-vascular-malformations-surgical-technique-and-results
#12
Jan-Karl Burkhardt, Ethan A Winkler, Michael T Lawton
OBJECTIVE Deep medial parietooccipital arteriovenous malformations (AVMs) and cerebral cavernous malformations (CCMs) are traditionally resected through an ipsilateral posterior interhemispheric approach (IPIA), which creates a deep, perpendicular perspective with limited access to the lateral margins of the lesion. The contralateral posterior interhemispheric approach (CPIA) flips the positioning, with the midline positioned horizontally for retraction due to gravity, but with the AVM on the upper side and the approach from the contralateral, lower side...
July 21, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28731387/a-comparative-analysis-of-pulmonary-and-critical-care-medicine-guideline-development-methodologies
#13
Noah C Schoenberg, Alan F Barker, John Bernardo, Robin R Deterding, Jerrold J Ellner, Dean R Hess, Neil R MacIntyre, Fernando J Martinez, Kevin C Wilson
BACKGROUND: The Institute of Medicine (IOM) standards for guideline development have had unintended negative consequences. A more efficient approach is desirable. OBJECTIVE: To determine whether a modified Delphi process early during guideline development discriminates recommendations that should be informed by a systematic review from those that can be based upon expert consensus. METHODS: The same questions addressed by IOM-compliant pulmonary or critical care guidelines were addressed by expert panels using a modified Delphi process, the Convergence of Opinion on Recommendations and Evidence (CORE) process...
July 21, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28731308/lead-toxicity-in-plants
#14
Hendrik Küpper
This review looks critically at the relevance of lead (Pb2+) toxicity and proposed mechanisms of Pb2+ -induced stress in algae and higher plants. As a basis, the current main sources of Pb2+ contamination in the environment are presented, which include agriculture, industry, and road traffic. Further, bioavailability of lead is discussed as a basis for evaluating the environmental relevance of the many studies on lead toxicity that have been published in the past decades. These studies suggest three main mechanisms of toxicity of Pb2+: inhibition of photosynthesis, oxidative stress, and "genotoxicity" including DNA damage and defects in mitosis...
April 10, 2017: Metal Ions in Life Sciences
https://www.readbyqxmd.com/read/28731291/critical-questions-advancing-the-health-of-female-veterans
#15
Lisa Muirhead, Priscilla Hall, Cedrella Jones-Taylor, Gari D Clifford, Tasha Felton-Williams, Kathy Williams
PURPOSE: Women are the fastest growing Veteran population in the United States and many receive all or part of their health care outside of the Department of Veterans Affairs (VA). The purpose of this article is to review the healthcare issues of women Veterans and discuss implications for care. DATA SOURCES: Review of selected literature, VA resources and guidelines, and expert opinion. CONCLUSIONS: Few providers are aware of the impact military service has on the health of women and fail to ask the all-important question, "Have you served in the military?" Recognizing women's military service can reveal important information that can answer perplexing clinical questions, aid in designing comprehensive plans of care, and enable women to receive the assistance needed to address complex physical and psychosocial issues to improve the quality of their lives...
July 21, 2017: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/28731230/effects-of-spray-drift-of-glyphosate-on-non-target-terrestrial-plants-a-critical-review
#16
REVIEW
Harald Cederlund
Glyphosate is a widely used broad-spectrum post-emergent herbicide used for weed control in both agricultural and non-agricultural settings. Spray drift of glyphosate can pose a risk to non-target terrestrial plants and plant communities outside the intended area of application, but the lack of a well-established predicted no-effect drift rate makes properly assessing such risk difficult. For this reason, a literature review and meta-analysis was carried out with the aim to determine which level of drift that is likely to cause harm to plants and to explore what spray-reducing targets that would be sufficiently protective...
July 21, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28731222/bio-nano-interface-and-environment-a-critical-review
#17
Gerardo Pulido-Reyes, Francisco Leganes, Francisca Fernández-Piñas, Roberto Rosal
The Bio-Nano interface is the boundary where the Engineered NanoMaterials (ENM) meet the biological system, exerting the biological function for what they have been designed or inducing adverse effects to other cells or organisms when they reach non-target scenarios, i.e: the natural environment. Research has been performed to determine the fate, transport, and toxic properties of ENM, but much of it focused on pristine or "as manufactured" ENM or where modifications of the materials were not assessed. This article reviews the most recent progresses regarding the Bio-Nano interface and the transformations that ENM suffer in the environment, paying special attention to the adsorption of environmental biomolecules on the surface of ENM...
July 21, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28731149/the-role-of-t-helper-17-cells-in-the-pathogenesis-of-hepatitis-b-virus-related-liver-cirrhosis-review
#18
Suxia Bao, Jianming Zheng, Guangfeng Shi
In chronic hepatitis B virus (HBV)-infected patients, T helper 17 (Th17) cells are significantly elevated. Th17 cells initiate immune‑mediated pathogenesis and have a critical role in the process of HBV‑related liver cirrhosis (HBV‑LC). The mechanisms underlying this process are attributed to Th17‑secreted cytokines, which include interleukin (IL)‑17, IL‑21 and IL‑22; however, a systemic analysis regarding these mechanisms has yet to be conducted. Therefore, the present study aimed to investigate the role of Th17 cells in the pathogenesis of HBV‑LC...
July 21, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28730922/investigating-the-ways-in-which-health-information-technology-can-promote-antimicrobial-stewardship-a-conceptual-overview
#19
Abby King, Kathrin M Cresswell, Jamie J Coleman, Sarah K Pontefract, Ann Slee, Robin Williams, Aziz Sheikh
Antimicrobial resistance is now recognised as a threat to health worldwide. Antimicrobial stewardship aims to promote the responsible use of antibiotics and is high on international and national policy agendas. Health information technology has the potential to support antimicrobial stewardship in a number of ways, but this field is still poorly characterised and understood. Building on a recent systematic review and expert roundtable discussions, we take a lifecycle perspective of antibiotic use in hospitals and identify potential targets for health information technology-based interventions to support antimicrobial stewardship...
January 1, 2017: Journal of the Royal Society of Medicine
https://www.readbyqxmd.com/read/28730914/the-health-economic-studies-of-hpv-vaccination-in-southeast-asian-countries-a-systematic-review
#20
Didik Setiawan, Monika Puri Oktora, Raymond Hutubessy, Arthorn Riewpaiboon, Maarten J Postma
The cervical cancer-related burden is an important problem in Southeast Asian (SEA) countries. However, only 3 out of 11 countries implement the comprehensive prevention program. Areas covered: This is a retrospective review from all relevant studies until 2015 from two main databases, MEDLINE/Pubmed and Embase in order to provide an evidence on the health economics of HPV vaccination in the region. Expert commentary: The implementation of HPV vaccination will generate substantial health and economic benefit in SEA countries since the number of cervical cancer cases in this region are generally high...
July 21, 2017: Expert Review of Vaccines
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