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https://www.readbyqxmd.com/read/28329869/50-years-of-cognitive-aging-theory
#1
Nicole D Anderson, Fergus I M Craik
Objectives: The objectives of this Introduction to the Journal of Gerontology: Psychological Sciences special issue on "50 Years of Cognitive Aging Theory" are to provide a brief overview of cognitive aging research prior to 1965 and to highlight significant developments in cognitive aging theory over the last 50 years. Method: Historical and recent theories of cognitive aging were reviewed, with a particular focus on those not directly covered by the articles included in this special issue...
December 9, 2016: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28329857/-play-and-people-living-with-dementia-a-humanities-based-inquiry-of-timeslips-and-the-alzheimer-s-poetry-project
#2
Aagje Swinnen, Kate de Medeiros
This paper is a humanities-based inquiry, applying Huizinga's framework of homo ludens ("man the player") to consider "play" in the context of two participatory arts programs (TimeSlips and the Alzheimer's Poetry Project) for people living with dementia. "Play," according to this Dutch historian, is at the heart of human activity and what gives meaning to life. Despite empirical research on play across the life course, play in dementia care is a relatively new idea. In addition, there is a dearth of reports based on humanistic inquiry which has slightly different goals than the growing body of qualitative and quantitative studies of participatory arts interventions...
January 18, 2017: Gerontologist
https://www.readbyqxmd.com/read/28328885/introducing-therioepistemology-the-study-of-how-knowledge-is-gained-from-animal-research
#3
REVIEW
Joseph P Garner, Brianna N Gaskill, Elin M Weber, Jamie Ahloy-Dallaire, Kathleen R Pritchett-Corning
This focus issue of Lab Animal coincides with a tipping point in biomedical research. For the first time, the scale of the reproducibility and translatability crisis is widely understood beyond the small cadre of researchers who have been studying it and the pharmaceutical and biotech companies who have been living it. Here we argue that an emerging literature, including the papers in this focus issue, has begun to congeal around a set of recurring themes, which themselves represent a paradigm shift. This paradigm shift can be characterized at the micro level as a shift from asking "what have we controlled for in this model?" to asking "what have we chosen to ignore in this model, and at what cost?" At the macro level, it is a shift from viewing animals as tools (the furry test tube), to viewing them as patients in an equivalent human medical study...
March 22, 2017: Lab Animal
https://www.readbyqxmd.com/read/28328576/chronic-pain-patients-perspectives-of-medical-cannabis
#4
Brian J Piper, Monica L Beals, Alexander T Abess, Stephanie D Nichols, Maurice Martin, Catherine M Cobb, Rebecca M DeKeuster
Medical cannabis (MC) is employed for a variety of conditions including chronic pain. The goal of this report was to provide an in-depth qualitative exploration of patient perspectives on the strengths and limitations of MC. Members of MC dispensaries (N = 984) in New England including two-thirds with a history of chronic pain completed an online survey. In response to "How effective is medical cannabis in treating your symptoms or conditions?", with options of 0% "no relief" to 100% "complete relief", the average was 74...
March 21, 2017: Pain
https://www.readbyqxmd.com/read/28328514/dynamic-uncertain-causality-graph-for-knowledge-representation-and-reasoning-utilization-of-statistical-data-and-domain-knowledge-in-complex-cases
#5
Qin Zhang, Quanying Yao
The dynamic uncertain causality graph (DUCG) is a newly presented framework for uncertain causality representation and probabilistic reasoning. It has been successfully applied to online fault diagnoses of large, complex industrial systems, and decease diagnoses. This paper extends the DUCG to model more complex cases than what could be previously modeled, e.g., the case in which statistical data are in different groups with or without overlap, and some domain knowledge and actions (new variables with uncertain causalities) are introduced...
March 17, 2017: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/28327187/schistosomiasis-is-more-prevalent-than-previously-thought-what-does-it-mean-for-public-health-goals-policies-strategies-guidelines-and-intervention-programs
#6
REVIEW
Daniel G Colley, Tamara S Andros, Carl H Campbell
Mapping and diagnosis of infections by the three major schistosome species (Schistosoma haematobium, S. mansoni and S. japonicum) has been done with assays that are known to be specific but increasingly insensitive as prevalence declines or in areas with already low prevalence of infection. This becomes a true challenge to achieving the goal of elimination of schistosomiasis because the multiplicative portion of the life-cycle of schistosomes, in the snail vector, favors continued transmission as long as even a few people maintain low numbers of worms that pass eggs in their excreta...
March 22, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28326053/improving-financial-management-via-contemplation-novel-interventions-and-findings-in-laboratory-and-applied-settings
#7
Ben Harkin
The present research tackles two main areas of financial mismanagement, namely avoiding debt-related information and underestimating expenditure. We draw upon research which has shown that inviting people to think about reasons for avoiding something actually serves to reduce the likelihood that they will then avoid it, and potentially improves what they know about it. Therefore, in three studies we investigated if prompting participants to contemplate their debt (Studies 1 and 2) and expenditure (Study 3) would decrease avoidance of debt-related information and improve estimates of expenditure, respectively...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28326011/the-virtual-trial
#8
Willem de Haan
Although brain network analysis in neurodegenerative disease is still a fairly young discipline, expectations are high. The robust theoretical basis, the straightforward detection and explanation of otherwise intangible complex system phenomena, and the correlations of network features with pathology and cognitive status are qualities that show the potential power of this new instrument. We expect "connectomics" to eventually better explain and predict that essential but still poorly understood aspect of dementia: the relation between pathology and cognitive symptoms...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28325831/landscape-genomic-insights-into-the-historic-migration-of-mountain-hemlock-in-response-to-holocene-climate-change
#9
Jeremy S Johnson, Keith D Gaddis, David M Cairns, Kranti Konganti, Konstantin V Krutovsky
PREMISE OF THE STUDY: Untangling alternative historic dispersal pathways in long-lived tree species is critical to better understand how temperate tree species may respond to climatic change. However, disentangling these alternative pathways is often difficult. Emerging genomic technologies and landscape genetics techniques improve our ability to assess these pathways in natural systems. We address the question to what degree have microrefugial patches and long-distance dispersal been responsible for the colonization of mountain hemlock (Tsuga mertensiana) on the Alaskan Kenai Peninsula...
March 21, 2017: American Journal of Botany
https://www.readbyqxmd.com/read/28324902/dysphagia-management-in-the-schools-past-present-and-future
#10
Cynthia R O'Donoghue, Elizabeth E Nottingham
As the number of speech-language pathologists (SLPs) responsible for swallowing and feeding services in the educational setting increases, guidance informing this specialized practice continues to emerge. Although SLPs have provided dysphagia management for children in medical settings for many years, the extension of dysphagia services to the schools is comparatively new. This shift in care delivery for what was previously a hospital-based practice is now occurring more frequently, and in an environment void of extensive medical supports (i...
April 2017: Seminars in Speech and Language
https://www.readbyqxmd.com/read/28324897/neonatal-feeding-behavior-as-a-complex-dynamical-system
#11
Eugene C Goldfield, Jennifer Perez, Katherine Engstler
The requirements of evidence-based practice in 2017 are motivating new theoretical foundations and methodological tools for characterizing neonatal feeding behavior. Toward that end, this article offers a complex dynamical systems perspective. A set of critical concepts from this perspective frames challenges faced by speech-language pathologists and allied professionals: when to initiate oral feeds, how to determine the robustness of neonatal breathing during feeding and appropriate levels of respiratory support, what instrumental assessments of swallow function to use with preterm neonates, and whether or not to introduce thickened liquids...
April 2017: Seminars in Speech and Language
https://www.readbyqxmd.com/read/28324809/the-internet-as-a-source-of-information-used-by-women-after-childbirth-to-meet-their-need-for-information-a-web-based-survey
#12
J Slomian, O Bruyère, J Y Reginster, P Emonts
OBJECTIVE: the aims of this survey were: (a) to evaluate the need of information after childbirth and what questions do 'new' mothers ask themselves; (b) to assess why and how women use the Internet to meet their need of information; (c) to describe how the respondents evaluate the reliability of the information found; (d) to understand how the information found on the Internet affects women's decision-making; and (e) to appreciate how health professionals react to the information found by the women...
March 14, 2017: Midwifery
https://www.readbyqxmd.com/read/28324739/generalizable-learning-practice-makes-perfect-but%C3%A2-at-what
#13
Aaron R Seitz
Practising a task can produce learning that generalizes to other tasks. Measurement of such generalization is complicated by how generalization doesn't always manifest simply as better performance on the new task, but also in the form of faster learning.
March 20, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28324029/vital-directions-for-health-and-health-care-priorities-from-a-national-academy-of-medicine-initiative
#14
Victor J Dzau, Mark B McClellan, J Michael McGinnis, Sheila P Burke, Molly J Coye, Angela Diaz, Thomas A Daschle, William H Frist, Martha Gaines, Margaret A Hamburg, Jane E Henney, Shiriki Kumanyika, Michael O Leavitt, Ruth M Parker, Lewis G Sandy, Leonard D Schaeffer, Glenn D Steele, Pamela Thompson, Elias Zerhouni
Importance: Recent discussion has focused on questions related to the repeal and replacement of portions of the Affordable Care Act (ACA). However, issues central to the future of health and health care in the United States transcend the ACA provisions receiving the greatest attention. Initiatives directed to certain strategic and infrastructure priorities are vital to achieve better health at lower cost. Objectives: To review the most salient health challenges and opportunities facing the United States, to identify practical and achievable priorities essential to health progress, and to present policy initiatives critical to the nation's health and fiscal integrity...
March 21, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28323747/supporting-a-youth-with-cerebellar-ataxia-into-adolescence
#15
Veronica Meneses, Zurisadai Gonzalez-Castillo, Veronica B Edgar, Marilyn Augustyn
Zoe, a 13-year-old white girl, presents as a new patient to your pediatric clinic with complaints of frequent emesis, anxiety, and learning problems, and previous diagnosis of cerebellar ataxia. Parents accompany Zoe and state, "it is really hard for her to go out, she gets sick and falls easily." She was born full term by vaginal delivery without complications. Given globally delayed milestones, she received early intervention services. Feeding problems began at infancy, including gastroesophageal reflux and aspiration pneumonia...
March 17, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28323083/new-signs-to-encourage-the-use-of-automated-external-defibrillators-by-the-lay-public
#16
Christopher M Smith, Michael C Colquhoun, Marc Samuels, Mark Hodson, Sarah Mitchell, Judy O'Sullivan
INTRODUCTION: Public Access Defibrillation - the use of Automated External Defibrillators (AEDs) by lay bystanders before the arrival of Emergency Medical Services - is an important strategy in delivering prompt defibrillation to victims of out-of-hospital cardiac arrest and can greatly improve survival rates. Such public-access AEDs are used rarely: one barrier might be poor understanding and content of current signage to indicate their presence. The aim of this project was to develop a sign, with public consultation, that better indicated the function of an AED, and an associated poster to encourage its use...
March 17, 2017: Resuscitation
https://www.readbyqxmd.com/read/28323064/the-relevance-of-%C3%AE-klotho-to-the-central-nervous-system-some-key-questions
#17
REVIEW
Marina Minto Lopes-Cararo, Caio Henrique Yokoyama Mazucanti, Cristoforo Scavone, Elisa Mitiko Kawamoto, Daniel Charles Berwick
α-Klotho is well described as an anti-aging protein, with critical roles in kidney function as a transmembrane co-receptor for FGF23, and as a soluble factor in serum. α-Klotho is also expressed in the choroid plexus, where it is released into the cerebrospinal fluid. Nonetheless, α-Klotho is also expressed in the brain parenchyma. Accumulating evidence indicates that this pool of α-Klotho, which we define as brain α-Klotho, may play important roles as a neuroprotective factor and in promoting myelination, thereby supporting healthy brain aging...
March 18, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/28322537/what-is-new-in-2017-update-on-fertility-preservation-in-cancer-patients
#18
Katharina Winkler-Crepaz, Bettina Böttcher, Bettina Toth, Ludwig Wildt, Susanne Hofer-Tollinger
Prevention of fertility loss due to cancer treatment as well as non-malignant causes has gained importance during the last decades. Clinically applied modalities for fertility preservation in cancer patients include cryopreservation of oocytes and embryos, the application of GnRH agonists, ovarian tissue banking, and cryopreservation of ejaculated or surgically extracted sperm. In addition, several new possibilities to restore fertility are currently being investigated, such as the establishment of in vitro culture systems for gonadal tissue, the development of artificial gonads, and the application of germline stem cells...
March 21, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/28321689/doing-the-right-thing-a-qualitative-investigation-of-retractions-due-to-unintentional-error
#19
Mohammad Hosseini, Medard Hilhorst, Inez de Beaufort, Daniele Fanelli
Retractions solicited by authors following the discovery of an unintentional error-what we henceforth call a "self-retraction"-are a new phenomenon of growing importance, about which very little is known. Here we present results of a small qualitative study aimed at gaining preliminary insights about circumstances, motivations and beliefs that accompanied the experience of a self-retraction. We identified retraction notes that unambiguously reported an honest error and that had been published between the years 2010 and 2015...
March 20, 2017: Science and Engineering Ethics
https://www.readbyqxmd.com/read/28321297/knowledge-is-power-a-quality-improvement-project-to-increase-patient-understanding-of-their-hospital-stay
#20
Eleanor Nicholson Thomas, Lloyd Edwards, Paul McArdle
Patients frequently leave hospital uninformed about the details of their hospital stay with studies showing that only 59.9% of patients are able to accurately state their diagnosis and ongoing management after discharge. 1 2 This places patients at a higher risk of complications. Educating patients by providing them with accurate and understandable information enables them to take greater control, potentially reducing readmission rates, and unplanned visits to secondary services whilst providing safer care and improving patient satisfaction...
2017: BMJ Quality Improvement Reports
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