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https://www.readbyqxmd.com/read/29156486/-update-in-obstetric-anesthesia-tried-and-trusted-methods-controversies-and-new-perspectives
#1
Peter Kranke, Thorsten Annecke, Dorothee H Bremerich, Daniel Chappell, Thierry Girard, Wiebke Gogarten, Robert Hanß, Lutz Kaufner, Sophie Neuhaus, Tobias Ninke, Thomas Standl, Stefan Weber, Yvonne Jelting, Thomas Volk
Since 1975, a plethora of lectures within the context of annual meetings relevant for the clinical care has been summarized in "what's new in obstetric anesthesia" by the society for Obstetric anesthesia and Perinatology which can be recommended to everyone interested in anaesthesiology in the delivery room. After the death of Gerard W. Ostheimer, Professor of Anaesthesiology at Brigham and Women's Hospital in Boston, Massachusetts, it became renamed the Gerard W. Ostheimer "what's new in obstetric anesthesia" lecture to honor his contributions to regional anesthesia and obstetric anaesthesia...
November 2017: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
https://www.readbyqxmd.com/read/29156442/charting-a-path-towards-non-destructive-biomarkers-in-threatened-wildlife-a-systematic-quantitative-literature-review
#2
REVIEW
Stephanie Chaousis, Frederic D L Leusch, Jason P van de Merwe
Threatened species are susceptible to irreversible population decline caused by adverse sub-lethal effects of chemical contaminant exposure. It is therefore vital to develop the necessary tools to predict and detect these effects as early as possible. Biomarkers of contaminant exposure and effect are widely applied to this end, and a significant amount of research has focused on development and validation of sensitive and diagnostic biomarkers. However, progress in the use biomarkers that can be measured using non-destructive techniques has been relatively slow and there are still many difficulties to overcome in the development of sound methods...
November 17, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29156401/nine-reasons-why-ecstasy-is-not-quite-what-it-used-to-be
#3
Jane Mounteney, Paul Griffiths, Alessandra Bo, Andrew Cunningham, Joao Matias, Alessandro Pirona
This paper explores the recent resurgence in use of ecstasy/MDMA in Europe and highlights keys areas of continuity and divergence between the ecstasy market of the 1990s and the current MDMA market. Based on a scoping study involving a targeted multi-source data collection exercise on MDMA, it highlights nine areas that have undergone some level of change, linked with both supply and demand for the drug. Factors discussed include: innovation in production techniques; changes in precursor chemical availability; the role of online markets; competition with other stimulants and new psychoactive substances; the increased availability of high-strength MDMA; and the shift from subcultural towards more mainstream use of the drug...
November 17, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29154619/complementarity-in-false-memory-illusions
#4
C J Brainerd, V F Reyna
For some years, the DRM illusion has been the most widely studied form of false memory. The consensus theoretical interpretation is that the illusion is a reality reversal, in which certain new words (critical distractors) are remembered as though they are old list words rather than as what they are-new words that are similar to old ones. This reality-reversal interpretation is supported by compelling lines of evidence, but prior experiments are limited by the fact that their memory tests only asked whether test items were old...
November 20, 2017: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/29154577/confounding-in-statistical-mediation-analysis-what-it-is-and-how-to-address-it
#5
Matthew J Valente, William E Pelham, Heather Smyth, David P MacKinnon
Psychology researchers are often interested in mechanisms underlying how randomized interventions affect outcomes such as substance use and mental health. Mediation analysis is a common statistical method for investigating psychological mechanisms that has benefited from exciting new methodological improvements over the last 2 decades. One of the most important new developments is methodology for estimating causal mediated effects using the potential outcomes framework for causal inference. Potential outcomes-based methods developed in epidemiology and statistics have important implications for understanding psychological mechanisms...
November 2017: Journal of Counseling Psychology
https://www.readbyqxmd.com/read/29154107/aripiprazole-in-treatment-of-gilles-de-la-tourette-syndrome-new-therapeutic-option
#6
REVIEW
Piotr Janik, Natalia Szejko
Aripiprazole is a dopamine D2- and serotonin 5-hydroxytryptamine (5-HT)1A receptor partial agonist and 5-HT2A receptor antagonist primarily used for the treatment of schizophrenia, bipolar disorder or depression with psychotic ideation. However, recently a number of new possible indications have been suggested, among them Gilles de la Tourette syndrome (GTS). In two randomized, double-blind, placebo-controlled studies in children and adolescents with GTS has been confirmed the efficacy of aripiprazole in tic reduction...
November 9, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/29153743/what-do-help-seeking-measures-assess-building-a-conceptualization-framework-for-help-seeking-intentions-through-a-systematic-review-of-measure-content
#7
REVIEW
Margaret M White, Bonnie A Clough, Leanne M Casey
Mental health services are underutilised by people who could benefit from treatment. Research into help-seeking intentions (HSI) is required to support interventions to increase service use. Existing HSI measures are not psychometrically robust and problems with content validity undermine research in this field. Our purpose was to create a clear conceptualization of HSI and systematically review the content of existing measures. Previous researchers had defined help-seeking and intentions separately, so the first step was to create a more comprehensive definition...
November 10, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/29153298/barriers-to-optimal-pain-management-in-aged-care-facilities-an-australian-qualitative-study
#8
Felicity Veal, Mackenzie Williams, Luke Bereznicki, Elizabeth Cummings, Angus Thompson, Gregory Peterson, Tania Winzenberg
Up to 80% of residents in aged care facilities (ACFs) experience pain, which is often suboptimally managed. To characterize pain management in ACFs and identify the barriers to optimal pain management. An exploratory descriptive qualitative study using semistructured interviews. Five Southern Tasmania, Australian ACFs. 23 staff members (18 nurses and 5 facility managers). Interviews were conducted from September to November 2015. Interviews included questions about how pain was measured or assessed, what happened if pain was identified, barriers to pain management, and potential ways to overcome these barriers...
November 15, 2017: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/29153273/women-s-experiences-of-having-depression-during-pregnancy-and-receiving-acupuncture-treatment-a-qualitative-study
#9
Simone M Ormsby, Hannah G Dahlen, Caroline A Smith
BACKGROUND: Research indicates some women experiencing depression during pregnancy are dissatisfied with conventional depression treatments due to incomplete effectiveness, dislike of side effects, unsatisfactory experiences with providers and concerns regarding in-utero and breastfeeding safety. Consequently, many explore alternative options including acupuncture. To further understand women's views, preferences and motivations in this regard, as well as their experiences of receiving acupuncture as part of a three-armed pragmatic randomised controlled trial evaluating acupuncture for antenatal depression in Sydney, Australia, in-depth interviews were conducted with a group of acupuncture recipients...
November 15, 2017: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/29153168/a-100-year-review-mammary-development-and-lactation
#10
R Michael Akers
What is old is new again-and with respect to the study of the mammary development and function in dairy animals, the expression resonates. Many of the mammary and milk production questions raised in the early years of the Journal of Dairy Science apply today. To be sure, scientists have filled in many details regarding, for example, identification of hormones and growth factors important in the control of mammary growth, the onset of copious milk production at calving, and maintenance of lactation. Early years focused on identification and subsequent availability of classic mammogenic, lactogenic, and galactopoietic hormones (e...
December 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29153166/a-100-year-review-practical-female-reproductive-management
#11
J S Stevenson, J H Britt
Basic knowledge of mechanisms controlling reproductive processes in mammals was limited in the early 20th century. Discoveries of physiologic processes and mechanisms made early in the last century laid the foundation to develop technologies and programs used today to manage and control reproduction in dairy cattle. Beyond advances made in understanding of gonadotropic support and control of ovarian and uterine functions in basic reproductive biology, advancements made in artificial insemination (AI) and genetics facilitated rapid genetic progress of economically important traits in dairy cattle...
December 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29152007/shoulder-arthroplasty-imaging-what-s-new
#12
REVIEW
T M Gregory, J Gregory, E Nicolas, J Pierrart, E Masmejean
Background: Shoulder arthroplasty, in its different forms (hemiarthroplasty, total shoulder arthroplasty and reverse total shoulder arthroplasty) has transformed the clinical outcomes of shoulder disorders. Improvement of general clinical outcome is the result of stronger adequacy of the treatment to the diagnosis, enhanced surgical techniques, specific implanted materials, and more accurate follow up. Imaging is an important tool in each step of these processes. Method: This article is a review article declining recent imaging processes for shoulder arthroplasty...
2017: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/29151676/jim-hyde-and-the-endor-connection-a-personal-account
#13
Klaus Möbius, Wolfgang Lubitz, Anton Savitsky
In this minireview, we report on our year-long EPR work, such as electron-nuclear double resonance (ENDOR), pulse electron double resonance (PELDOR) and ELDOR-detected NMR (EDNMR) at X-band and W-band microwave frequencies and magnetic fields. This report is dedicated to James S. Hyde and honors his pioneering contributions to the measurement of spin interactions in large (bio)molecules. From these interactions, detailed information is revealed on structure and dynamics of macromolecules embedded in liquid-solution or solid-state environments...
2017: Applied Magnetic Resonance
https://www.readbyqxmd.com/read/29151448/underreporting-trends-of-occupational-illnesses-in-mexico
#14
Luis Antonio Moreno-Torres, Carmelita Elizabeth Ventura-Alfaro
OBJECTIVE: To report trends underreporting levels of occupational illnesses (OI) in Mexico from 2000 to 2015. METHODS: An ecological study was conducted. Data on OI was obtained from the Statistical Memories of the Mexican Institute of Social Security. We used univariate sensitivity analysis to estimate the average value and range. RESULTS: During the 2000-2015 period, the estimated average OI underreporting in the Mexican population was 89...
November 18, 2017: Journal of Occupational Health
https://www.readbyqxmd.com/read/29151432/implementing-a-6-day-physiotherapy-service-in-rehabilitation-exploring-staff-perceptions
#15
Erin L Caruana, Suzanne S Kuys, Jane Clarke, Sandra G Brauer
Objective Australian weekend rehabilitation therapy provision is increasing. Staff engagement optimises service delivery. The present mixed-methods process evaluation explored staff perceptions regarding implementation of a 6-day physiotherapy service in a private rehabilitation unit.Methods All multidisciplinary staff working in the rehabilitation unit were surveyed regarding barriers, facilitators and perceptions of the effect of a 6-day physiotherapy service on length of stay (LOS) and patient goal attainment at three time points: before and after implementation, as well as after modification of a 6-day physiotherapy service...
November 20, 2017: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/29151366/the-150-most-important-questions-in-cancer-research-and-clinical-oncology-series-questions-76-85-edited-by-chinese-journal-of-cancer
#16
EDITORIAL
(no author information available yet)
Since the beginning of 2017, Chinese Journal of Cancer has published a series of important questions in cancer research and clinical oncology to promote cancer research and accelerate collaborations. In this article, 10 questions are presented as followed. Question 76. How to develop effective therapeutics for cancer cachexia? Question 77. How can we develop preclinical animal models to recapitulate clinical situations of cancer patients for more effective anti-cancer drug development? Question 78. How can we develop novel effective therapeutics for pancreatic cancer and hepatocellular carcinoma? Question 79...
November 20, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/29151362/elimination-of-schistosomiasis-the-tools-required
#17
REVIEW
Robert Bergquist, Xiao-Nong Zhou, David Rollinson, Jutta Reinhard-Rupp, Katharina Klohe
BACKGROUND: Historically, the target in the schistosomiasis control has shifted from infection to morbidity, then back to infection, but now as a public health problem, before moving on to transmission control. Currently, all endemic countries are encouraged to increase control efforts and move towards elimination as required by the World Health Organization (WHO) roadmap for the global control of the neglected tropical diseases (NTDs) and the WHA65.21 resolution issued by the World Health Assembly...
November 20, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29150976/salt-bridge-interactions-within-the-%C3%AE-2-integrin-%C3%AE-7-helix-mediate-force-induced-binding-and-shear-resistance-ability
#18
Xiao Zhang, Linda Li, Ning Li, Xinyu Shu, Lüwen Zhou, Shouqin Lü, Shenbao Chen, Debin Mao, Mian Long
The functional performance of αI domain α7 helix in β2 integrin activation depends on the allostery of the α7 helix, which axially slides down; therefore, it is critical to elucidate what factors regulate the allostery. In this study, we determined that there were two conservative salt bridge interaction pairs that constrain both the upper and bottom ends of the α7 helix. Molecular Dynamics (MD) simulations for three β2 integrin members of LFA-1 (αL β2 ), Mac-1 (αM β2 ) and αx β2 indicated that the magnitude of the salt bridge interaction is related to the stability of the αI domain and the strength of the corresponding force-induced allostery...
November 18, 2017: FEBS Journal
https://www.readbyqxmd.com/read/29149938/novel-interventions-what-s-new-and-the-future
#19
REVIEW
Jean-Louis Vincent, David Grimaldi
Despite decades of sepsis research, no specific therapies for sepsis have emerged and current management still relies on source control, antibiotics, and organ support. With improved understanding of sepsis pathophysiology and the development of new techniques to enable better characterization of patients with sepsis, clinical trials are beginning to better target new interventions at those patients most likely to respond. This article discusses advances in sepsis therapeutics designed to improve endothelial cell function, purify the blood to help restore immune homeostasis, and provide immunostimulation for patients with immune exhaustion...
January 2018: Critical Care Clinics
https://www.readbyqxmd.com/read/29149856/naukan-ethnobotany-in-post-soviet-times-lost-edibles-and-new-medicinals
#20
Kevin A Jernigan, Olga S Belichenko, Valeria B Kolosova, Darlene J Orr
BACKGROUND: This study focuses on health-related plant use among speakers of the critically endangered Naukan language (Inuit-Yupik-Unangan family) in the Russian Far East. The Naukan people were forced, in 1958, under Soviet consolidation, to move from their original settlement on Cape Dezhnev, leading to significant changes in spiritual worldview, subsistence, social structure, and language proficiency in the years that followed. Here, we focus on changes that elders report in their edible, medicinal, and spiritual uses of local plant species since their childhood...
November 17, 2017: Journal of Ethnobiology and Ethnomedicine
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