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https://www.readbyqxmd.com/read/28817580/criticality-predicts-maximum-irregularity-in-recurrent-networks-of-excitatory-nodes
#1
Yahya Karimipanah, Zhengyu Ma, Ralf Wessel
A rigorous understanding of brain dynamics and function requires a conceptual bridge between multiple levels of organization, including neural spiking and network-level population activity. Mounting evidence suggests that neural networks of cerebral cortex operate at a critical regime, which is defined as a transition point between two phases of short lasting and chaotic activity. However, despite the fact that criticality brings about certain functional advantages for information processing, its supporting evidence is still far from conclusive, as it has been mostly based on power law scaling of size and durations of cascades of activity...
2017: PloS One
https://www.readbyqxmd.com/read/28817431/challenges-in-health-care-simulation-are-we-learning-anything-new
#2
Kerm Henriksen, David Rodrick, Erin N Grace, P Jeffrey Brady
The growth of health care simulation in schools of medicine and nursing is noteworthy, as is the increasingly sophisticated simulation technology, support from funding agencies and foundations for research, well-attended annual conferences, and continued interest of accreditation and certification groups. Yet there are concerns preventing the full value of health care simulation to be realized when examined from a patient safety perspective. Basic questions are asked by funders of patient safety research when assessing past simulation projects undertaken to advance patient safety: Are the safety and quality of care to patients actually improved, and is something new being learned regarding the optimal use of simulation? Concerns focus on pursuing the right research questions to learn something new about the most effective use of simulation; doing more with simulation than simply providing an interesting, stand-alone educational experience; attending more seriously to how skill acquisition, maintenance, and progression get managed; and encouraging investigators, funders, and reviewers to expand their vision regarding what constitutes important inquiry and evidence in health care simulation...
August 16, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28817401/challenges-in-the-anesthetic-management-of-ambulatory-patients-in-the-mri-suites
#3
Jasper Deen, Yzabel Vandevivere, Peter Van de Putte
PURPOSE OF REVIEW: MRI is becoming an indispensable diagnostic tool. The need for prolonged motion-free periods has substantially increased the need for deep sedation or anesthesia in a challenging environment. This review summarises recent literature with respect to pharmacological sedative strategies, nonpharmacological alternative approaches, airway management and safety issues in the ambulatory setting. RECENT FINDINGS: Most literature researches the pediatric patient population...
August 16, 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/28817221/neuroprotective-effects-of-honokiol-from-chemistry-to-medicine
#4
REVIEW
Sylwia Talarek, Joanna Listos, Davide Barreca, Ester Tellone, Antoni Sureda, Seyed Fazel Nabavi, Nady Braidy, Seyed Mohammad Nabavi
The incidence of neurological disorders is growing in developed countries together with increased lifespan. Nowadays, there are still no effective treatments for neurodegenerative pathologies, which make necessary to search for new therapeutic agents. Natural products, most of them used in traditional medicine, are considered promising alternatives for the treatment of neurodegenerative diseases. Honokiol is a natural bioactive phenylpropanoid compound, belonging to the class of neolignan, found in notable amounts in the bark of Magnolia tree, and has been reported to exert diverse pharmacological properties including neuroprotective activities...
August 17, 2017: BioFactors
https://www.readbyqxmd.com/read/28816914/congenital-hypotonia-in-toddlerhood
#5
Naomi Steiner, Alcy Torres, Arathi Reddy, Marilyn Augustyn
David is a 22-month-old boy who is new to your practice. He recently moved from a rural area in the Midwest. His father is in the United States Air Force, and his mother works as a full-time homemaker. Their household includes 5 older siblings. The family moves every year because of the father's Air Force placement.David was born full-term in Virginia, with no reported pregnancy complications and no alcohol, tobacco, or drug exposure. He was delivered vaginally, with Apgar scores of 7 and 9, respectively and no respiratory issues...
August 9, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28816903/what-s-new-in-limb-lengthening-and-deformity-correction
#6
Reggie C Hamdy, Mitchell Bernstein, Austin T Fragomen, S Robert Rozbruch
No abstract text is available yet for this article.
August 16, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28816791/resting-state-functional-connectivity-in-the-human-connectome-project-current-status-and-relevance-to-understanding-psychopathology
#7
Deanna M Barch
A key tenet of modern psychiatry is that psychiatric disorders arise from abnormalities in brain circuits that support human behavior. Our ability to examine hypotheses around circuit-level abnormalities in psychiatric disorders has been made possible by advances in human neuroimaging technologies. These advances have provided the basis for recent efforts to develop a more complex understanding of the function of brain circuits in health and of their relationship to behavior-providing, in turn, a foundation for our understanding of how disruptions in such circuits contribute to the development of psychiatric disorders...
August 16, 2017: Harvard Review of Psychiatry
https://www.readbyqxmd.com/read/28815759/prediction-of-reduction-potentials-of-copper-proteins-with-continuum-electrostatics-and-density-functional-theory
#8
Nicholas J Fowler, Christopher F Blanford, Jim Warwicker, Samuel de Visser
Blue copper proteins, such as azurin, show dramatic changes in Cu2+/Cu+ reduction potential upon mutation over the full physiological range. Hence they have important functions in electron transfer and oxidation chemistry and may have potential in biotechnology. The details of what determines these reduction potential changes upon mutation are still unclear. Moreover, it has been difficult to model and predict the reduction potential of azurin mutants and currently no unique procedure or workflow pattern exists...
August 16, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28815139/semanticfind-locating-what-you-want-in-a-patient-record-not-just-what-you-ask-for
#9
John M Prager, Jennifer J Liang, Murthy V Devarakonda
We present a new model of patient record search, called SemanticFind, which goes beyond traditional textual and medical synonym matches by locating patient data that a clinician would want to see rather than just what they ask for. The new model is implemented by making extensive use of the UMLS semantic network, distributional semantics, and NLP, to match query terms along several dimensions in a patient record with the returned matches organized accordingly. The new approach finds all clinically related concepts without the user having to ask for them...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28814702/reorganizing-hospital-space-the-1894-plague-epidemic-in-hong-kong-and-the-germ-theory
#10
Kyu-Hwan Sihn
This paper examined whether the preventive measures taken by the Hong Kong's colonial authorities were legitimate during the 1894 Hong Kong plague epidemic, and illuminated the correlation between the plague epidemic and hospital space in Hong Kong in the late 19th century. The quarantine measures taken by the colonial authorities were neither a clear-cut victory for Western medicine nor for a rational quarantine based on scientific medical knowledge. Hong Kong's medical officials based on the miasma theory, and focused only on house-to-house inspections and forced quarantine or isolation, without encouraging people to wear masks and without conducting disinfection...
April 2017: ┼Či Sahak
https://www.readbyqxmd.com/read/28814595/bleeding-ectopic-duodenal-varix-use-of-a-new-microvascular-plug-mvp-device-along-with-transjugular-intrahepatic-portosystemic-shunt-tipss
#11
Richa Bhardwaj, Gaurav Bhardwaj, Erik Bee, Raffi Karagozian
Ectopic varices (ECV) occur along the gastrointestinal (GI) tract outside the common variceal sites and represent 2%-5% of all GI variceal bleeds with mortality rates up to 40%. Management is challenging because of inaccessibility and increased risk of rebleeding. We report what is to our knowledge the first clinical use of a new microvascular plug (MVP) with transjugular intrahepatic portosystemic shunt (TIPSS) for a bleeding duodenal varix (DV). A 68-year-old man presented with melena. Endoscopy demonstrated a grade II varix in the second part of the duodenum with red wale sign...
August 16, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28814082/environmental-processes-at-the-solid-liquid-interface-what-constitutes-new-physical-insights
#12
D Howard Fairbrother, Franz M Geiger
No abstract text is available yet for this article.
August 17, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28814049/wearable-sensing-for-rehabilitation-after-stroke-bimanual-jerk-asymmetry-encodes-unique-information-about-the-variability-of-upper-extremity-recovery
#13
Diogo S de Lucena, Oliver Stoller, Justin B Rowe, Vicky Chan, David J Reinkensmeyer
Wearable sensing is a new tool for quantifying upper extremity (UE) rehabilitation after stroke. However, it is unclear whether it provides information beyond what is available through standard clinical assessments. To investigate this question, people with a chronic stroke (n=9) wore accelerometers on both wrists for 9 hours on a single day during their daily activities. We used principal components analysis (PCA) to characterize how novel kinematic measures of jerk and acceleration asymmetry, along with conventional measures of limb use asymmetry and clinical function, explained the behavioral variance of UE recovery across participants...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813729/carrier-screening-what-is-new
#14
EDITORIAL
Keith Hansen
No abstract text is available yet for this article.
April 2017: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/28813426/sexual-reproduction-in-plagiogrammacean-diatoms-first-insights-into-the-early-pennates
#15
Irena Kaczmarska, Benjamin S Gray, James M Ehrman, Mary Thaler
The genera Plagiogramma and Dimeregramma are members of a small, but evolutionarily important group of diatoms, the "basal" araphids. They are sister to all other pennates, both araphid and raphid taxa. Thus, their phylogenetic position carries the potential for providing insights into the earliest pennates. We documented sexual reproduction, mating system and sex cell development in the first members of the "basal" araphid clade ever investigated. The mating system in all these species involved heterothally...
2017: PloS One
https://www.readbyqxmd.com/read/28813302/divorce-and-health-good-data-in-need-of-better-theory
#16
REVIEW
David A Sbarra, James A Coan
A very large literature links the experiences of marital separation and divorce to risk for a range of poor distal health outcomes, including early death. What is far less clear, however, is the mechanistic pathways that convey this risk. Several plausible mechanisms are identified in the literature, and the central thesis of this paper is that the empirical study of divorce and health will benefit enormously from a renewed reliance on theory to dictate how these mechanisms of action may unfold over time. This review emphasizes the roles of attachment and social baseline theories in making specific mechanistic predictions and highlights the ways in which these perspectives can contribute new empirical knowledge on risk and resilience following marital dissolution...
February 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28813262/parenting-in-acculturation-two-contemporary-research-designs-and-what-they-tell-us
#17
REVIEW
Marc H Bornstein
Massive population transfers are common today. To understand how immigrants negotiate variation and adjustment as they settle in a new culture, researchers have explored acculturation, the changes that individuals and groups undergo as a result of contact with a culture not their own. Parents have crucial roles to play in acculturation. Parenting is instantiated in cognitions and practices, and cognitions and practices of parents are multifaceted and influenced by many factors, including parents' own individual characteristics, their children, and their cultural experiences...
June 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28812842/governance-and-capacity-to-manage-resilience-of-health-systems-towards-a-new-conceptual-framework
#18
Karl Blanchet, Sara L Nam, Ben Ramalingam, Francisco Pozo-Martin
The term resilience has dominated the discourse among health systems researchers since 2014 and the onset of the Ebola outbreak in West Africa. There is wide consensus that the global community has to help build more resilient health systems. But do we really know what resilience means, and do we all have the same vision of resilience? The present paper presents a new conceptual framework on governance of resilience based on systems thinking and complexity theories. In this paper, we see resilience of a health system as its capacity to absorb, adapt and transform when exposed to a shock such as a pandemic, natural disaster or armed conflict and still retain the same control over its structure and functions...
April 4, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812811/the-rise-of-post-truth-populism-in-pluralist-liberal-democracies-challenges-for-health-policy
#19
EDITORIAL
Ewen Speed, Russell Mannion
Recent years have witnessed the rise of populism and populist leaders, movements and policies in many pluralist liberal democracies, with Brexit and the election of Trump the two most recent high profile examples of this backlash against established political elites and the institutions that support them. This new populism is underpinned by a post-truth politics which is using social media as a mouthpiece for 'fake news' and 'alternative facts' with the intention of inciting fear and hatred of 'the other' and thereby helping to justify discriminatory health policies for marginalised groups...
February 12, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812275/a-method-for-improving-the-integrity-of-peer-review
#20
Mehdi Dadkhah, Mohsen Kahani, Glenn Borchardt
Peer review is the most important aspect of reputable journals. Without it, we would be unsure about whether the material published was as valid and reliable as is possible. However, with the advent of the Internet, scientific literature has now become subject to a relatively new phenomenon: fake peer reviews. Some dishonest researchers have been manipulating the peer review process to publish what are often inferior papers. There are even papers that explain how to do it. This paper discusses one of those methods and how editors can defeat it by using a special review ID...
August 15, 2017: Science and Engineering Ethics
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