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https://www.readbyqxmd.com/read/29224257/models-of-care-for-non-invasive-ventilation-in-the-acute-copd-comparison-of-three-tertiary-hospitals-act3-study
#1
Kerry Parker, Vara Perikala, Ali Aminazad, Zheng Deng, Brigitte Borg, Catherine Buchan, Jo Toghill, Louis B Irving, Jeremy Goldin, David Charlesworth, Ajay Mahal, Suhith Illesinghe, Matthew T Naughton, Alan Young
BACKGROUND AND OBJECTIVE: Non-invasive ventilation (NIV) improves clinical outcomes in hypercapnic acute exacerbations of COPD (AECOPD), but the optimal model of care remains unknown. METHODS: We conducted a prospective observational non-inferiority study comparing three models of NIV care: general ward (Ward) (1:4 nurse to patient ratio, thrice weekly consultant ward round), a high dependency unit (HDU) (1:2 ratio, twice daily ward round) and an intensive care unit (ICU) (1:1 ratio, twice daily ward round) model in three similar teaching tertiary hospitals...
December 10, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29224255/the-highest-mortality-rates-in-childhood-dilated-cardiomyopathy-occur-during-the-first-year-after-diagnosis
#2
Shalan Fadl, Håkan Wåhlander, Katja Fall, Yang Cao, Jan Sunnegårdh
AIM: The aim of the study was to assess the incidence, mortality and morbidity of dilated cardiomyopathy (DCM) and non-compaction of the left ventricle (LVNC) in Swedish children. METHODS: We reviewed hospital records of all children with dilated cardiomyopathy (DCM) or left ventricular non-compaction cardiomyopathy (LVNC) up to the age of 18 in the healthcare region of western Sweden from 1991 to 2015. RESULTS: In total, 69 cases (61% males) were identified...
December 9, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29224247/cortisol-and-blood-pressure-levels-decreased-in-fathers-during-the-first-hour-of-skin-to-skin-contact-with-their-premature-babies
#3
Natalia Varela, Réjean Tessier, George Tarabulsy, Tamarha Pierce
AIM: Premature birth is an extremely stressful experience. In 2013 to 2014 we explored the physiological stress responses of fathers during their first skin-to-skin contact with their new baby. METHODS: We recruited 49 fathers whose partners had given birth to a premature baby of up to 33 weeks and three days. The study, in the neonatal intensive care unit (NICU) of a Quebec hospital, measured the physiological stress responses of the fathers before and after they first experienced skin-to-skin contact with their new baby...
December 9, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29224241/cost-effectiveness-of-bariatric-surgery-in-adolescents-with-severe-obesity-in-the-uk
#4
M Panca, R M Viner, B White, T Pandya, H Melo, M Adamo, R Batterham, D Christie, S Kinra, S Morris
Evidence shows that surgery for severe obesity in adults improves health and psychological functioning, and is cost-effective. Data on bariatric surgery for adolescents with severe obesity are extremely limited, with no evidence on cost-effectiveness. We evaluated the lifetime cost-effectiveness of bariatric surgery compared with no surgery in adolescents with severe obesity from the UK's National Health Service perspective. Eighteen adolescents with body mass index ≥40 kg m-2 who underwent bariatric surgery (laparoscopic Roux en Y Gastric Bypass [RYGB] [N = 9], and laparoscopic Sleeve Gastrectomy [SG] [N = 9]) at University College London Hospitals between January 2008 and December 2013 were included...
December 10, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/29224237/major-haemorrhage-fatalities-in-the-australian-national-coronial-database
#5
Jacob S Gipson, Erica M Wood, Merrole F Cole-Sinclair, Zoe McQuilten, Neil Waters, Noel W Woodford
OBJECTIVE: The aim of the study is to describe the epidemiology of major bleeding fatalities. METHODS: A case series analysis of Australia's National Coronial Information System was conducted. Keywords were used to search for closed cases of major haemorrhage in the state of Victoria for the period 1 January 2009 to 31 December 2011. Coroners' findings, autopsy reports and police reports of cases were reviewed. Demographic data were extracted, and cases were assigned to a clinical bleeding context...
December 10, 2017: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29224234/an-observational-study-of-benzodiazepine-prescription-during-inpatient-alcohol-detoxification-for-patients-with-versus-without-chronic-pretreatment-with-high-dosage-baclofen
#6
Laura Martinez, Florence Vorspan, Xavier Declèves, Julien Azuar, Maeva Fortias, Franck Questel, Alexandra Dereux, Leslie Grichy, Hélène Barreteau, Frank Bellivier, Jean-Pierre Lépine, Vanessa Bloch
High dose baclofen is prescribed as a maintenance treatment to reduce alcohol use in patients with alcohol use disorder. Nevertheless, some patients still have massive alcohol intakes and require inpatient alcohol withdrawal. AIM: to compare the oral dose of benzodiazepine prescribed to manage alcohol withdrawal symptoms in patients with versus without steady state pre-treatment with high dose baclofen. METHODS: Retrospective chart review study. Prescribed benzodiazepine dose expressed in diazepam-equivalent was compared between groups...
December 10, 2017: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/29224211/medication-reconciliation-at-two-teaching-hospitals-in-australia-a-missed-opportunity
#7
Nimmi Athuraliya, Jasminka Sarunac, Jane Robertson
Medication reconciliation prevents medication related harm at patient hospitalisation. This cross-sectional study demonstrated that the Hunter New England Health Admission Medication History Form that supports the two processes is underutilised in two hospitals in New South Wales with many doctors unaware of the form and pharmacists facing understaffing and time constraints for completing it. Triaging of patients and, more collaboration between doctors and pharmacists are required for efficient in-hospital medication reconciliation...
December 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/29224207/acute-kidney-injury-is-under-recognised-and-under-reported-in-hospitalised-patients-in-australia
#8
Tim Mitchell, Elisabeth Feher, Gillian Mitchell, Aron Chakera
Acute kidney injury (AKI) in hospitalised patients is associated with adverse outcomes; however, it remains unrecognised and under-reported. A total of 48 045 serum creatinine results from 8129 tertiary hospital inpatients were reviewed. The prevalence of AKI was 4.33%. Mortality was significantly higher in patients with AKI (16.76%) compared to those without AKI (1.88%, P < 0.001). Documentation of AKI in discharge summaries was poor.
December 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/29224205/healthcare-acquired-infections-prevention-strategies
#9
Shelanah A Fernando, Timothy J Gray, Thomas Gottlieb
Healthcare-acquired infections (HAI) impact on patient care and have cost implications for the Australian healthcare system. The management of HAI is exacerbated by rising rates of antimicrobial resistance (AMR). Health-care workers and a contaminated hospital environment are increasingly implicated in the transmission and persistence of multi-resistant organisms (MRO), as well as other pathogens, such as Clostridium difficile. This has resulted in a timely focus on a range of HAI prevention actions. Core components include antimicrobial stewardship, to reduce overuse and ensure evidence-based antimicrobial use; infection prevention strategies, to control MRO - particularly methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus spp...
December 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/29224200/mortality-in-acute-non-invasive-ventilation
#10
Dugal B Smith, George T P Tay, Karen Hay, Jijo Antony, Brendan Bell, Frances B Kinnear, Deanne L Curtin, James Douglas
A prospective study of non-invasive ventilation at The Prince Charles Hospital outside of the intensive care unit from March 2015 to March 2016 was performed. Overall 69 patients were included. Acute hypercapnic respiratory failure was the most common indication (n = 59; 85%). 49 (71%) had multifactorial respiratory failure. 15 (22%) patients died. Premorbid inability to perform self-care (P = 0.001) and the combination of mean pH < 7.25 and mean PaCO2 ≥ 75 mmHg within 2 h of NIV initiation (P = 0.037) were significantly associated with mortality...
December 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/29224196/diagnostic-accuracy-of-posterior-cervical-angle-and-cervical-length-in-the-prediction-of-successful-induction-of-labor
#11
Akram M Al-Adwy, Sherin M Sobh, Doaa S Belal, Eman F Omran, Amr Hassan, Ahmed H Saad, Mai M Afifi, Adel M Nada
OBJECTIVE: To determine the accuracy of the posterior cervical angle (PCA) compared with the cervical length and the Bishop score in predicting the outcome of induction of labor (IOL). METHODS: The present prospective observational study included IOL candidates who had their PCA and cervical length assessed by transvaginal ultrasonography and the Bishop score at the Obstetrics and Gynecology Department, Kasr El-Aini Hospital, Cairo University, Cairo, Egypt, between April 1 and July 31, 2017...
December 10, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29224133/epidemiology-of-chronic-hepatitis-b-virus-in-ireland-using-routinely-collected-surveillance-and-administrative-data-2004-2014
#12
Caroline E van Gemert, Niamh Murphy, Tara A Mitchell, Margaret E Hellard, Thornton Thornton
BACKGROUND: Ireland has a low prevalence of chronic hepatitis B virus (HBV) infection; however, there are limited recently published epidemiological data. This study aimed to describe the epidemiology of chronic HBV in Ireland between 2004 and 2014 using routine surveillance data and identify and interrogate additional data sources in Ireland to complement the interpretation of HBV surveillance data. METHODS: Routinely collected passive surveillance data of notified cases of HBV infection were collated for 2004-2014...
December 9, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29224126/perception-of-community-on-attachment-and-resilience-according-to-closing-of-hospitals
#13
Kichan Yoon, Munjae Lee
This study includes a comparison analysis of how community resilience and its influence factor of community attachment were changed before and after the closing of the hospital in the rural community. In order to analyze the influence factors of healthcare and medical vulnerability on community resilience, as well as the mean difference from before and after the closing of the hospital, this study conducted matching sample t test, hierarchical regression analysis, difference in differences (DID) analysis. The results indicate that community attachment consists of such factors as closeness, preference, affective bond, and identity, and they showed significance in confidence...
December 9, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/29224120/spontaneous-cervical-artery-dissection-is-accompanied-by-a-hypercoagulable-state-and-simultaneous-inflammatory-condition
#14
Johann Otto Pelz, Kristian Harms, Michael Metze, Dominik Michalski
BACKGROUND: Spontaneous cervical artery dissections (sCAD) are often preceded by infections. However, existing data about inflammatory parameters remained inconsistent. Remarkably, concurrent information about the coagulation system, whose affection seems also reasonable to cause ischaemic events, are still lacking in sCAD patients. Thus, this study explores the association between the inflammatory and coagulation system in patients with sCAD. METHODS: The parameters leukocyte and thrombocyte count, C-reactive protein, fibrinogen, D-dimer, activated partial thromboplastin time (aPTT) and prothrombin time were extracted from hospital-based medical records of patients (n = 60) with sCAD and compared with those of a control group (n = 97) from a prospective observational stroke study...
December 9, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/29224114/coated-platelet-trends-predict-short-term-clinical-outcomeafter-subarachnoid-hemorrhage
#15
Bappaditya Ray, Vijay M Pandav, Eleanor A Mathews, David M Thompson, Lance Ford, Lori K Yearout, Bradley N Bohnstedt, Shuchi Chaudhary, George L Dale, Calin I Prodan
Aneurysmal subarachnoid hemorrhage (aSAH) is associated with high socio-economic burden. Prothrombotic states of early brain injury (EBI) and delayed cerebral ischemia (DCI) after aSAH determine morbidity and mortality. To understand how activated platelets might contribute to such prothrombotic states, we studied trends in coated-platelets during EBI and DCI periods. Serial blood samples from a prospective cohort of aSAH patients were collected and assayed for coated-platelet levels. Patient's coated-platelet level during post-hospital discharge follow-up served as an estimate of baseline...
December 9, 2017: Translational Stroke Research
https://www.readbyqxmd.com/read/29224054/lesion-characteristics-and-procedural-outcomes-of-re-attempted-percutaneous-coronary-interventions-for-chronic-total-occlusion
#16
Masaki Tanabe, Kenji Kodama, Kohei Asada, Takeo Kunitomo
This study was performed to investigate lesion characteristics and procedural outcomes of re-attempted percutaneous coronary intervention (PCI) for chronic total occlusion (CTO). Prior failure of percutaneous revascularization of CTO has been identified as an independent predictor of failure at subsequent attempts. However, procedural outcomes of re-attempted PCI for CTO have not been elucidated. We evaluated lesion characteristics and procedural outcomes in 310 consecutive patients undergoing CTO-PCI, and compared the results between re-attempted (n = 59) and initial procedures (n = 251)...
December 9, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/29224053/spontaneous-bacteremia-and-spontaneous-bacterial-peritonitis-share-similar-prognosis-in-patients-with-cirrhosis-a-cohort-study
#17
Sebastián Marciano, Melisa Dirchwolf, Carla S Bermudez, Natalia Sobenko, Leila Haddad, Federico Genre Bert, Laura Barcán, Astrid Smud, Maria Lourdes Posadas-Martínez, Diego Giunta, Adrián Gadano
BACKGROUND AND AIMS: Spontaneous bacteremia is a poorly characterized infection in patients with cirrhosis. We compared the incidence of mortality and acute kidney injury in patients with spontaneous bacterial peritonitis and spontaneous bacteremia, and identified risk factors for mortality and acute kidney injury in patients with spontaneous bacteremia. METHODS: We performed a retrospective cohort study of patients with cirrhosis and spontaneous bacteremia or spontaneous bacterial peritonitis from 2008 to 2016 at Hospital Italiano, Buenos Aires...
December 9, 2017: Hepatology International
https://www.readbyqxmd.com/read/29224020/association-between-glcci1-promoter-polymorphism-rs37972-and-post-transplant-hypertension-in-renal-transplant-recipients
#18
Aki Mafune Hamada, Izumi Yamamoto, Yasuyuki Nakada, Akimitsu Kobayashi, Yusuke Koike, Jun Miki, Hiroki Yamada, Yudo Tanno, Ichiro Ohkido, Nobuo Tsuboi, Hiroyasu Yamamoto, Mitsuyoshi Urashima, Takashi Yokoo
BACKGROUND/AIMS: Post-transplant hypertension is highly prevalent in renal transplant recipients and is a risk factor for graft loss, cardiovascular disease and death. Glucocorticoid is used to prevent rejection, but simultaneously increases the risk of post-transplant hypertension. The glucocorticoid-induced transcript 1 (GLCCI1) promoter polymorphism (rs37972) has been reported to be associated with response to glucocorticoid therapy in asthma. We therefore examined the association between GLCCI1 promoter polymorphism and post-transplant hypertension in renal transplant recipients...
December 8, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29224001/dental-caries-and-developmental-defects-of-enamel-in-the-primary-dentition-of-preterm-infants-case-control-observational-study
#19
Ina Manuela Schüler, Stefanie Haberstroh, Kristin Dawczynski, Thomas Lehmann, Roswitha Heinrich-Weltzien
AIM: Assessment of dental health in the primary dentition of preterm infants (PTI) including investigation of mother- and infant-related risk factors in a case-control study design. MATERIAL AND METHODS: One hundred twenty-eight infants aged 3-4 years were included. Sixty-four PTI (27 males) were randomly selected from the preterm registry of the Jena University Hospital. As a control group served 64 full-term infants (FTI) recruited from the Department of Paediatric Dentistry, matched for age and sex...
December 9, 2017: Caries Research
https://www.readbyqxmd.com/read/29223938/-prevalence-of-anti-toxoplasma-gondii-antibodies-in-blood-donors-in-buenos-aires-city-from-1967-to-2017
#20
Federico J Kaufer, Liliana A Carral, Matías T Messina, María Vanessa Schneider, Miriam Méndez, Lourdes Herrera, Cristina B Freuler, Ricardo A Durlach
A prevalence study of antibodies anti Toxoplasma gondii in voluntary blood donors who attended the hemotherapy service at the Hospital Alemán during the first four months of the years 1997, 2007 and 2017 was carried out and the results were compared to the study carried out in 1967. The sera where processed with the Sabin Feldman Dye Test. The global average seroprevalence in 1967 was 67.0% (CI95%, 64.4%-69.6%); in 1997, 35.0% (CI95%, 33.3%-38.3%); in 2007, 31.9% (CI95%, 29.6%-34.2%) and in 2017, 21.2% (CI95%, 19...
2017: Medicina
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