keyword
MENU ▼
Read by QxMD icon Read
search

PAPs

keyword
https://www.readbyqxmd.com/read/29470836/role-of-vancomycin-minimum-inhibitory-concentrations-by-modified-population-analysis-profile-method-and-clinical-outcomes-in-high-inoculum-methicillin-resistant-staphylococcus-aureus-infections
#1
Trang D Trinh, Evan J Zasowski, Kimberly C Claeys, Anthony M Casapao, Matthew Compton, Abdalhamid Lagnf, Shravya D Kidambi, Donald P Levine, Michael J Rybak
INTRODUCTION: Vancomycin remains the standard of care for invasive methicillin-resistant Staphylococcus aureus (MRSA) infections. Treatment failures from heteroresistant vancomycin-intermediate subpopulations (hVISA) are challenging to detect. Minimum inhibitory concentrations (MIC) identified by modified population analysis profile (PAP) is an alternative testing method. The aim of this study was to evaluate the role of PAP MIC on vancomycin failures in two high inoculum infections: MRSA infective endocarditis and pneumonia...
February 22, 2018: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/29470167/role-of-race-ethnicity-language-and-insurance-in-use-of-cervical-cancer-prevention-services-among-low-income-hispanic-women-2009-2013
#2
John Heintzman, Brigit Hatch, Gloria Coronado, David Ezekiel, Stuart Cowburn, Octavio Escamilla-Sanchez, Miguel Marino
INTRODUCTION: Hispanic women in the United States have an elevated risk of cervical cancer, but the existing literature does not reveal why this disparity persists. METHODS: We performed a retrospective cohort analysis of 17,828 low-income women aged 21 to 64 years seeking care at Oregon community health centers served by a hosted, linked electronic health record during 2009 through 2013. We assessed the odds of having had Papanicolaou (Pap) tests and receiving human papillomavirus (HPV) vaccine, by race/ethnicity, insurance status, and language...
February 22, 2018: Preventing Chronic Disease
https://www.readbyqxmd.com/read/29470057/mass-spectrometry-based-immunoassay-for-the-quantification-of-banned-ruminant-processed-animal-proteins-in-vegetal-feeds
#3
Andreas E Steinhilber, Felix F Schmidt, Wael Naboulsi, Hannes Planatscher, Alicia Niedzwiecka, Jutta Zagon, Albert Braeuning, Alfonso Lampen, Thomas O Joos, Oliver Poetz
The ban of processed animal proteins (PAPs) in feed for farmed animals introduced in 2001 was one of the main EU measures to control the bovine spongiform encephalopathy (BSE) crisis. Currently, microscopy and polymerase chain reaction (PCR), are the official methods for the detection of illegal PAPs in feed. However, the progressive release of the feed ban, recently with the legalization of non-ruminant PAPs for the use in aquaculture, requires the development of alternative methods to determine the species origin and the source (legal or not)...
February 22, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29468176/inhibition-of-the-potassium-channel-kv1-3-reduces-infarction-and-inflammation-in-ischemic-stroke
#4
Yi-Je Chen, Hai M Nguyen, Izumi Maezawa, Lee-Way Jin, Heike Wulff
Objective: Inhibitors of the voltage-gated K+ channel Kv1.3 are currently in development as immunomodulators for the treatment of autoimmune diseases. As Kv1.3 is also expressed on microglia and has been shown to be specifically up-regulated on "M1-like" microglia, we here tested the therapeutic hypothesis that the brain-penetrant small-molecule Kv1.3-inhibitor PAP-1 reduces secondary inflammatory damage after ischemia/reperfusion. Methods: We studied microglial Kv1...
February 2018: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/29465024/a-prospective-study-of-women-with-ascus-or-lsil-pap-smears-at-baseline-and-hpv-e6-e7-mrna-positive-a-3-year-follow-up
#5
M T Bruno, M Ferrara, V Fava, G Barrasso, M M Panella
Human papillomavirus (HPV) testing is used in the triage of women with a borderline smear result. The efficiency of testing women with a low-grade squamous intraepithelial lesion (LSIL) and atypical squamous cells of undetermined significance (ASCUS) is less clear. For this reason we used a new HPV test that detects E6/E7 messenger RNA (mRNA), which might have a higher specificity. The objective of this prospective study was to assess whether HPV E6/E7 mRNA positivity in women with ASCUS and LSIL at baseline, is able to predict those women who have a high risk of developing a histological cervical intraepithelial neoplasia (CIN2) or worse lesion...
February 21, 2018: Epidemiology and Infection
https://www.readbyqxmd.com/read/29462939/peripheral-b-cell-subset-distribution-in-primary-antiphospholipid-syndrome
#6
Lorena Alvarez, Leyre Riancho, Jime Calvo-Alén, Marcos Lopez Hoyos, Victor Martinez-Taboada
BACKGROUND: B-cell differentiation and B-cell tolerance checkpoints may be different in antiphospholipid syndrome (APS) from systemic lupus erythematosus (SLE) and can help to understand differences between them. Our aim was to define alterations of B-cell subsets in patients with primary APS (pAPS) and to compare them with SLE patients and healthy controls (HC). METHODS: Cross-sectional study including three study groups: 37 patients with pAPS, 11 SLE patients, and 21 age- and gender-matched HC...
February 16, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29461819/enhanced-arylamine-n-oxygenase-activity-of-polymer-enzyme-assemblies-by-facilitating-electron-transferring-efficiency
#7
Libo Zhang, Yanmei Xu, Thomas M Makris, Qian Wang
A novel N-oxygenase coated core-shell nanoparticle was generated through the co-assembly of poly(4-vinylpyridine) (P4VP) and arylamine N-oxygenase CmlI. The resulting enzyme-hybridized particles, P4VP-CmlI, showed excellent catalytic activities on the oxidation of two arylamine substrates, i.e. p-aminophenol (pAP) and p-aminobenzoic acid (pABA), using a surrogate redox system or a peroxide shunt as co-oxidants. In comparison to the free enzyme, P4VP-CmlI particles exhibited a significantly enhanced catalytic efficiency when using pyridine nucleotide (NADH) and proper redox mediators...
February 20, 2018: Biomacromolecules
https://www.readbyqxmd.com/read/29461283/the-impact-of-education-about-cervical-cancer-and-human-papillomavirus-on-women-s-healthy-lifestyle-behaviors-and-beliefs-using-the-precede-educational-model
#8
Zeliha Koç, Emel Kurtoğlu Özdeş, Serap Topatan, Tuğba Çinarli, Asuman Şener, Esra Danaci, Cansu Atmaca Palazoğlu
BACKGROUND: Early detection of cervical cancer improves the chances of successful treatment. OBJECTIVE: The aim of this study was to determine the effect of education about cervical cancer and human papillomavirus on the healthy lifestyle, behavior, and beliefs of Turkish women who were without cancer, using the PRECEDE education model. METHODS: This qualitative and quantitative study was conducted as a prospective, randomized, 2-group (intervention and control) trial at a community training center in north Turkey...
February 14, 2018: Cancer Nursing
https://www.readbyqxmd.com/read/29458709/quality-of-life-with-pap-therapy-for-obese-children
#9
Tracy L Ivy, James S Kemp
No abstract text is available yet for this article.
February 13, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29458697/long-term-impact-of-sleep-disordered-breathing-on-quality-of-life-in-children-with-obesity
#10
Sherri L Katz, Joanna E MacLean, Nicholas Barrowman, Lynda Hoey, Linda Horwood, Glenda N Bendiak, Valerie G Kirk, Stasia Hadjiyannakis, Laurent Legault, Bethany J Foster, Evelyn Constantin
STUDY OBJECTIVES: (1) To determine baseline quality of life (QOL) among children with obesity and newly diagnosed moderate-severe sleep-disordered breathing (SDB) and to compare it to the reported QOL of children with obesity or SDB alone and healthy children. (2) To evaluate QOL change after 1 year. METHODS: A prospective multicenter cohort study was conducted in children (8-16 years) with obesity, prescribed positive airway pressure (PAP) therapy for moderate-severe SDB...
February 13, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29456837/synaptic-neuron-astrocyte-communication-is-supported-by-an-order-of-magnitude-analysis-of-inositol-tris-phosphate-diffusion-at-the-nanoscale-in-a-model-of-peri-synaptic-astrocyte-projection
#11
Pavel Montes de Oca Balderas, Horacio Montes de Oca Balderas
Background: Astrocytes were conceived for decades only as supporting cells of the brain. However, the observation of Ca2+ waves in astrocyte synctitia, their neurotransmitter receptor expression and gliotransmitter secretion suggested a role in information handling, conception that has some controversies. Synaptic Neuron-Astrocyte metabotropic communication mediated by Inositol tris-phosphate (SN-AmcIP3) is supported by different reports. However, some models contradict this idea and Ca2+ stores are 1000 ± 325 nm apart from the Postsynaptic Density in the Perisynaptic Astrocyte Projections (PAP's), suggesting that SN-AmcIP3 is extrasynaptic...
2018: BMC Biophysics
https://www.readbyqxmd.com/read/29455859/heterozygous-mutations-in-oas1-cause-infantile-onset-pulmonary-alveolar-proteinosis-with-hypogammaglobulinemia
#12
Kazutoshi Cho, Masafumi Yamada, Kazunaga Agematsu, Hirokazu Kanegane, Noriko Miyake, Masahiro Ueki, Takuma Akimoto, Norimoto Kobayashi, Satoru Ikemoto, Mishie Tanino, Atsushi Fujita, Itaru Hayasaka, Satoshi Miyamoto, Mari Tanaka-Kubota, Koh Nakata, Masaaki Shiina, Kazuhiro Ogata, Hisanori Minakami, Naomichi Matsumoto, Tadashi Ariga
Pulmonary alveolar proteinosis (PAP) is characterized by accumulation of a surfactant-like substance in alveolar spaces and hypoxemic respiratory failure. Genetic PAP (GPAP) is caused by mutations in genes encoding surfactant proteins or genes encoding a surfactant phospholipid transporter in alveolar type II epithelial cells. GPAP is also caused by mutations in genes whose products are implicated in surfactant catabolism in alveolar macrophages (AMs). We performed whole-exome sequence analysis in a family affected by infantile-onset PAP with hypogammaglobulinemia without causative mutations in genes associated with PAP: SFTPB, SFTPC, ABCA3, CSF2RA, CSF2RB, and GATA2...
February 12, 2018: American Journal of Human Genetics
https://www.readbyqxmd.com/read/29454079/a-novel-metric-that-quantifies-risk-stratification-for-evaluating-diagnostic-tests-the-example-of-evaluating-cervical-cancer-screening-tests-across-populations
#13
Hormuzd A Katki, Mark Schiffman
Our work involves assessing whether new biomarkers might be useful for cervical-cancer screening across populations with different disease prevalences and biomarker distributions. When comparing across populations, we show that standard diagnostic accuracy statistics (predictive values, risk-differences, Youden's index and Area Under the Curve (AUC)) can easily be misinterpreted. We introduce an intuitively simple statistic for a 2 × 2 table, Mean Risk Stratification (MRS): the average change in risk (pre-test vs...
February 14, 2018: Preventive Medicine
https://www.readbyqxmd.com/read/29453639/upper-airway-obstruction-induced-by-non-invasive-ventilation-using-an-oronasal-interface
#14
Valentin Schellhas, Christian Glatz, Ingo Beecken, Angelika Okegwo, Anna Heidbreder, Peter Young, Matthias Boentert
BACKGROUND: On initiation of long-term non-invasive ventilation (NIV), intermittent upper airway obstruction has rarely been described as possibly treatment-induced. Inspiratory pressure effects and the use of an oronasal interface may promote obstructive events in some patients with neuromuscular disease (NMD) and amyotrophic lateral sclerosis (ALS) in particular. METHODS: We evaluated clinical data from 212 patients in whom NIV was initiated using an oronasal mask...
February 17, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29451465/the-pap-test-20th-century-success-story-21st-century-has-been
#15
Jan Greene
This old standby's ultimate demise will likely take place when cervical cancer incidence declines as the HPV vaccine starts to take effect at a population level. New guidelines are being written, but insurers could have a major influence on how closely those guidelines are followed. So far, though, they haven't waded very far into the Pap-HPV debate.
February 2018: Managed Care
https://www.readbyqxmd.com/read/29449412/hemodynamic-characteristics-in-significant-symptomatic-and-asymptomatic-primary-mitral-valve-regurgitation-at-rest-and-during-exercise
#16
Rine Bakkestrøm, Ann Banke, Nicolaj L Christensen, Redi Pecini, Akhmadjon Irmukhamedov, Mads Andersen, Barry A Borlaug, Jacob E Møller
BACKGROUND: In severe asymptomatic primary mitral valve regurgitation without risk factors, surgery strategy is controversial. We sought to clarify whether being symptomatic corresponds to the hemodynamic burden and reduced exercise capacity. A better understanding of this may contribute to optimize timing of surgery. METHODS AND RESULTS: Subjects with asymptomatic (New York Heart Association functional class I, n=29) or symptomatic (New York Heart Association functional class II and III, n=28) significant primary mitral valve regurgitation (effective regurgitant orifice, ≥0...
February 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29446818/heart-involvement-in-systemic-sclerosis
#17
Ihsen Zairi, Lilia Baili, Khadija Mzoughi, Manel Dridi, Zouhaier Jnifene, Fatma Boussema
INTRODUCTION: Primary and secondary heart involvement in systemic sclerosis are important mortality predictors. Aim of this study was to investigate by standard echocardiography associated to pulsed-tissue Doppler imaging, six-minute walk test (6MWT) and BNP level cardiac manifestation in 30 patients with ScS and to establish a strategy to detect and to evaluate this complication. METHODS: This was a cross-sectional study conducted over a period of 16 months: a total of 30 consecutive patients with ScS diagnosed as proposed by the American college of Rheumatology and the European League Against Rheumatism 2013 and who were hospitalized in Internal Medicine department of Habib Thameur hospital underwent cardiac assessment...
March 2017: La Tunisie Médicale
https://www.readbyqxmd.com/read/29441569/epidemiologic-associations-of-hpv-positive-oropharyngeal-cancer-and-pre-cancerous-cervical-lesions
#18
M M Rietbergen, A A J D van Bokhoven, B I Lissenberg-Witte, D A M Heideman, C R Leemans, R H Brakenhoff, E Bloemena
PURPOSE: Human papillomavirus (HPV)- induced oropharyngeal squamous cell carcinoma (OPSCC) is still increasing worldwide. We aimed to investigate if the HPV-prevalence of OPSCC in the Netherlands is rising as well, especially in female patients. In addition, we evaluated the association between HPV-positive OPSCC and suspicious Pap results of the cervix in these female patients. PATIENTS AND METHODS: Patients with OPSCC treated in the period 2000-2015 at the VU University Medical Center Amsterdam, were included (n=926)...
February 14, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29440214/-it-has-saved-thousands-of-lives-so-why-change-it-content-analysis-of-objections-to-cervical-screening-programme-changes-in-australia
#19
Helena M Obermair, Rachael H Dodd, Carissa Bonner, Jesse Jansen, Kirsten McCaffery
OBJECTIVES: The incidence and mortality of cervical cancer have halved since introduction of the Australian cervical screening programme in 1991, involving 2-yearly Pap smears from ages 18-69 years. In 2017, the programme changed to 5- yearly primary human papillomavirus (HPV) testing for women aged 25-74 years. This study investigated reasons for opposition to the renewed screening programme within the open-ended comments of an online petition, 'Stop May 1st Changes to Pap Smears-Save Women's Lives', opposing the changes, which received over 70 000 signatures and almost 20 000 comments...
February 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/29438367/randomised-study-shows-that-repeated-self-sampling-and-hpv-test-has-more-than-two-fold-higher-detection-rate-of-women-with-cin2-histology-than-pap-smear-cytology
#20
Inger Gustavsson, Riina Aarnio, Malin Berggrund, Julia Hedlund-Lindberg, Ann-Sofi Strand, Karin Sanner, Ingrid Wikström, Stefan Enroth, Matts Olovsson, Ulf Gyllensten
BACKGROUND: This randomised study compared the detection rate of cervical intraepithelial neoplasia-positive (CIN2+) based on histology in women performing repeated self-sampling of vaginal fluid (VF) for human papillomavirus (HPV) test with a control group following the ordinary screening by Pap smear cytology. METHODS: 36390 women aged 30-49 years scheduled for invitation to organised screening were randomised in two groups, one to perform self-sampling of VF for HPV test (n=17 997, HPV arm) and the other group to perform screening by PAP smear cytology (n=18 393, control arm)...
February 13, 2018: British Journal of Cancer
keyword
keyword
61858
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"