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https://www.readbyqxmd.com/read/29735835/methicillin-resistant-staphylococcus-aureus-intracranial-abscess-an-analytical-series-and-review-on-molecular-surgical-and-medical-aspects
#1
Veena Kumari Haradara Bahubali, Priya Vijayan, Vasundhra Bhandari, Nagarathna Siddaiah, Dwarakanath Srinivas
Purpose: Intracranial abscess caused by methicillin-resistant Staphylococcus aureus (MRSA) is rare and unexplored. The aim of the present study is to examine the prevalence, clinical and molecular characteristics, treatment options and outcome of MRSA intracranial abscess over a period of 6 years. Patientsand Methods: A total of 21 patients were included in this retrospective study. The demographic and clinical details of all the patients were collected. Molecular typing including staphylococcal cassette chromosome mec typing, spa typing and polymerase chain reaction of Panton-Valentine leucocidin toxin (PVL) gene for the latter 6 isolates was performed...
January 2018: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29735560/the-novel-phage-derived-antimicrobial-agent-hy-133-is-active-against-livestock-associated-methicillin-resistant-staphylococcus-aureus-la-mrsa
#2
Ursula Kaspar, Jorge A de Haro Sautto, Sonja Molinaro, Georg Peters, Evgeny A Idelevich, Karsten Becker
Livestock-associated, methicillin-resistant Staphylococcus aureus (LA-MRSA) are increasingly migrating from livestock into human and animal health care settings. Alternative substances are wanted to overcome the drawbacks of currently available drugs applied for MRSA eradication. The recombinant bacteriophage endolysin HY-133 has been proven as an active agent against S. aureus Here, the in vitro activity of HY-133 was studied against a large collection of genetically diverse LA-MRSA revealing its high activity against mecA, mecB and mecC LA-MRSA...
May 7, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29718930/emergence-of-highly-prevalent-ca-mrsa-st93-as-an-occupational-risk-in-people-working-on-a-pig-farm-in-australia
#3
Shafi Sahibzada, Marta Hernández-Jover, David Jordan, Peter C Thomson, Jane Heller
BACKGROUND: The occurrence of livestock-associated (LA) MRSA (ST398) in pig herds has emerged as a threat to occupational safety in many parts of the world. Recently, an outbreak of skin lesions due to MRSA occurred in workers at a pig farm in regional Australia and both the humans and pigs were shown to have a high prevalence of carriage of either the human-strain ST93 or porcine strain ST398. This study closely scrutinises this outbreak to determine factors associated with MRSA carriage amongst the workers...
2018: PloS One
https://www.readbyqxmd.com/read/29518661/environmental-and-public-health-related-risk-of-veterinary-zinc-in-pig-production-using-denmark-as-an-example
#4
REVIEW
John Jensen, Niels Christian Kyvsgaard, Antonio Battisti, Keith Edward Baptiste
At great economic cost, important steps have been taken over the last many decades to reduce and control emissions of heavy metals in order to protect the environment and public health. Monitoring has confirmed the success of these policies with progressive declines of heavy metals in for example air, sewage sludge and environmental samples. For zinc, such improvements may nevertheless be counter-acted by its widely usage as a feed additive and veterinary medicinal product to piglets in the post-weaning period resulting in reduced occurrence of diarrhea and improvement of daily weight gain...
May 2018: Environment International
https://www.readbyqxmd.com/read/29408035/increase-of-zinc-resistance-in-german-human-derived-livestock-associated-mrsa-between-2000-and-2014
#5
Sarah van Alen, Ursula Kaspar, Evgeny A Idelevich, Robin Köck, Karsten Becker
PROBLEM ADDRESSED: Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA), particularly of the clonal complex (CC) 398, emerged as zoonotic pathogens predominantly among humans with direct or indirect livestock contact, but also in healthcare settings. The factors contributing to the success of LA-MRSA are only poorly understood. OBJECTIVE: During the past years, the use of heavy metal compounds as feed-supplements was found to influence the co-selection of LA-MRSA in pig herds...
February 2018: Veterinary Microbiology
https://www.readbyqxmd.com/read/29378646/detection-and-analysis-of-methicillin-resistant-human-adapted-sequence-type-398-allows-insight-into-community-associated-methicillin-resistant-staphylococcus-aureus-evolution
#6
Lei He, Hong-Xiang Zheng, Yanan Wang, Katherine Y Le, Qian Liu, Jun Shang, Yingxin Dai, Hongwei Meng, Xing Wang, Tianming Li, Qianqian Gao, Juanxiu Qin, Huiying Lu, Michael Otto, Min Li
BACKGROUND: Severe infections with highly virulent community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) are a global problem. However, the molecular events defining the evolution of CA-MRSA are still poorly understood. MRSA of sequence type (ST) 398 is known to frequently infect livestock, while ST398 isolates infecting humans are commonly methicillin-susceptible or represent MRSA originating from livestock-associated (LA)-MRSA. METHODS: We used whole genome sequencing of newly detected CA-MRSA ST398 isolates, in comparison to geographically matched LA-MRSA and methicillin-sensitive ST398, to determine their evolutionary history...
January 29, 2018: Genome Medicine
https://www.readbyqxmd.com/read/29365048/survival-of-la-mrsa-in-dust-from-swine-farms
#7
Louise Feld, Hans Bay, Øystein Angen, Anders Rhod Larsen, Anne Mette Madsen
Dust is suspected to be an important factor in transmission of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) between pigs and pig farmers and their families. The aim of this study was to determine the rate of decay for Staphylococcus aureus and LA-MRSA in dust from swine farms. Electrostatic dust fall collectors (EDCs) were used for passive sampling of settling airborne dust in 11 stable sections from six swine farms. Extraction, plating, identification, and enumeration of cultivable S...
February 13, 2018: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/29182655/a-mechanistic-model-for-spread-of-livestock-associated-methicillin-resistant-staphylococcus-aureus-la-mrsa-within-a-pig-herd
#8
Anna Irene Vedel Sørensen, Nils Toft, Anette Boklund, Carmen Espinosa-Gongora, Kaare Græsbøll, Jesper Larsen, Tariq Halasa
Before an efficient control strategy for livestock-associated methicillin resistant Staphylococcus aureus (LA-MRSA) in pigs can be decided upon, it is necessary to obtain a better understanding of how LA-MRSA spreads and persists within a pig herd, once it is introduced. We here present a mechanistic stochastic discrete-event simulation model for spread of LA-MRSA within a farrow-to-finish sow herd to aid in this. The model was individual-based and included three different disease compartments: susceptible, intermittent or persistent shedder of MRSA...
2017: PloS One
https://www.readbyqxmd.com/read/29162210/letter-to-the-editor-livestock-associated-meticillin-resistant-staphylococcus-aureus-la-mrsa-austria-2013
#9
Werner Ruppitsch, Stefanie Monschein, Sarah Lepuschitz, Franz Allerberger, Burkhard Springer
No abstract text is available yet for this article.
November 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/29113628/livestock-associated-meticillin-resistant-staphylococcus-aureus-mrsa-among-human-mrsa-isolates-european-union-european-economic-area-countries-2013
#10
Pete Kinross, Andreas Petersen, Robert Skov, Evelyn Van Hauwermeiren, Annalisa Pantosti, Frédéric Laurent, Andreas Voss, Jan Kluytmans, Marc J Struelens, Ole Heuer, Dominique L Monnet
Currently, surveillance of livestock-associated meticillin-resistant Staphylococcus aureus (LA-MRSA) in humans in Europe is not systematic but mainly event-based. In September 2014, the European Centre for Disease Prevention and Control (ECDC) initiated a questionnaire to collect data on the number of LA-MRSA from human samples (one isolate per patient) from national/regional reference laboratories in European Union/European Economic Area (EU/EEA) countries in 2013. Identification of LA-MRSA as clonal complex (CC) 398 by multilocus sequence typing (MLST) was preferred, although surrogate methods such as spa -typing were also accepted...
November 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/29101193/methicillin-resistant-staphylococcus-aureus-sequence-type-st-5-isolates-from-health-care-and-agricultural-sources-adhere-equivalently-to-human-keratinocytes
#11
Samantha J Hau, Steven Kellner, Kirsten C Eberle, Ursula Waack, Susan L Brockmeier, Jisun S Haan, Peter R Davies, Timothy Frana, Tracy L Nicholson
Staphylococcus aureus is part of the nasal microbiome of many humans and has become a significant public health burden due to infections with antibiotic-resistant strains, including methicillin-resistant S. aureus (MRSA) strains. Several lineages of S. aureus , including MRSA, are found in livestock species and can be acquired by humans through contact with animals. These livestock-associated MRSA (LA-MRSA) isolates raise public health concerns because of the potential for livestock to act as reservoirs for MRSA outside the hospital setting...
January 15, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29097452/draft-genome-sequences-of-14-livestock-associated-methicillin-resistant-staphylococcus-aureus-sequence-type-398-isolates-from-swine-farms-in-the-united-states
#12
Samantha J Hau, Darrell O Bayles, David P Alt, Timothy S Frana, Tracy L Nicholson
Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) is a bacterium carried by or obtained from swine and other livestock. The initial and predominant swine-associated LA-MRSA sequence type (ST) identified is ST398. Here, we present 14 draft genome sequences from LA-MRSA ST398 isolates found in the United States.
November 2, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29097451/draft-genome-sequences-of-63-swine-associated-methicillin-resistant-staphylococcus-aureus-sequence-type-5-isolates-from-the-united-states
#13
Samantha J Hau, Darrell O Bayles, David P Alt, Timothy S Frana, Tracy L Nicholson
Methicillin-resistant Staphylococcus aureus colonizes humans and other animals such as swine. Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) sequence type 5 (ST5) isolates are a public concern due to their pathogenicity and ability to acquire mobile genetic elements. This report presents draft genome sequences for 63 LA-MRSA ST5 isolates in the United States.
November 2, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29048488/clinical-and-molecular-features-of-mdr-livestock-associated-mrsa-st9-with-staphylococcal-cassette-chromosome-mecxii-in-humans
#14
Chih-Jung Chen, Tsai-Ling Yang Lauderdale, Chin-Te Lu, Yu-Yu Chuang, Chien-Chang Yang, Ting-Shu Wu, Chun-Yi Lee, Min-Chi Lu, Wen-Chien Ko, Yhu-Chering Huang
Objectives: Clonal complex (CC) 9 is a prevalent livestock-associated (LA) MRSA clone in Asia whose pathogenicity in humans remains unknown. Methods: In 2012, we identified a patient with CC9-MRSA infection linked to livestock. After screening 3328 clinical MRSA isolates from a national database, eight isolates (0.24%) collected between 1998 and 2012 were further confirmed to be of CC9. The detailed molecular features of the nine human CC9 strains and phylogenetic relatedness to animal CC9 strains were characterized with WGS...
January 1, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29025945/draft-genome-sequences-of-nine-livestock-associated-methicillin-resistant-staphylococcus-aureus-sequence-type-5-isolates-obtained-from-humans-after-short-term-swine-contact
#15
Samantha J Hau, Darrell O Bayles, David P Alt, Timothy S Frana, Tracy L Nicholson
Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) sequence type 5 (ST5) has raised concerns surrounding the potential for these isolates to colonize or cause disease in humans with swine contact. Here, we report draft genome sequences for nine LA-MRSA ST5 isolates obtained from humans after short term swine contact.
October 12, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29025944/draft-genome-sequences-of-nine-livestock-associated-methicillin-resistant-staphylococcus-aureus-sequence-type-5-isolates-from-humans-with-long-term-swine-contact
#16
Samantha J Hau, Darrell O Bayles, David P Alt, Peter R Davies, Jisun S Haan, Tracy L Nicholson
Humans have been found to harbor livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) isolates. LA-MRSA isolates are considered adapted to colonizing livestock and less pathogenic in humans than their hospital- and community-acquired counterparts. Here, we present nine LA-MRSA sequence type 5 isolates from veterinarians with long-term swine contact.
October 12, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28963329/antimicrobial-resistance-update-la-mrsa
#17
(no author information available yet)
No abstract text is available yet for this article.
September 30, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28804601/policy-implementation-for-methicillin-resistant-staphylococcus-aureus-in-seven-european-countries-a-comparative-analysis-from-1999-to-2015
#18
Takuya Kinoshita, Hironobu Tokumasu, Shiro Tanaka, Axel Kramer, Koji Kawakami
Background: Policies to reduce methicillin-resistant Staphylococcus aureus (MRSA) infections, both healthcare-acquired (HA-MRSA) and livestock-associated (LA-MRSA) are implemented Europe-wide, but evaluations are difficult for countries yet to implement such policies. A descriptive study was conducted, describing multinational MRSA rates and policy implementation, focusing on MRSA mandatory surveillance. We also investigated antibiotic use and MRSA rates and the use of veterinary antibiotics. Methods: This study used Europe-wide surveillance data on infectious diseases (EARS-Net), antibiotic consumption (ESAC-Net), and veterinary medicine (ESVAC)...
2017: Journal of Market Access & Health Policy
https://www.readbyqxmd.com/read/28798188/complete-genome-sequence-of-a-livestock-associated-methicillin-resistant-staphylococcus-aureus-sequence-type-5-isolate-from-the-united-states
#19
Samantha J Hau, Darrell O Bayles, David P Alt, Timothy S Frana, Tracy L Nicholson
Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) may be the largest MRSA reservoir outside the hospital setting. One concern with LA-MRSA is the acquisition of novel mobile genetic elements by these isolates. Here, we report the complete genome sequence of a swine LA-MRSA sequence type 5 isolate from the United States.
August 10, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28798187/complete-genome-sequence-of-livestock-associated-methicillin-resistant-staphylococcus-aureus-sequence-type-398-isolated-from-swine-in-the-united-states
#20
Samantha J Hau, Darrell O Bayles, David P Alt, Timothy S Frana, Tracy L Nicholson
Methicillin-resistant Staphylococcus aureus (MRSA) colonizes and causes disease in many animal species. Livestock-associated MRSA (LA-MRSA) isolates are represented by isolates of the sequence type 398 (ST398). These isolates are considered to be livestock adapted. This report provides the complete genome sequence of one swine-associated LA-MRSA ST398 isolate from the United States.
August 10, 2017: Genome Announcements
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