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https://www.readbyqxmd.com/read/28804601/policy-implementation-for-methicillin-resistant-staphylococcus-aureus-in-seven-european-countries-a-comparative-analysis-from-1999-to-2015
#1
Takuya Kinoshita, Hironobu Tokumasu, Shiro Tanaka, Axel Kramer, Koji Kawakami
Background: Policies to reduce methicillin-resistant Staphylococcus aureus (MRSA) infections, both healthcare-acquired (HA-MRSA) and livestock-associated (LA-MRSA) are implemented Europe-wide, but evaluations are difficult for countries yet to implement such policies. A descriptive study was conducted, describing multinational MRSA rates and policy implementation, focusing on MRSA mandatory surveillance. We also investigated antibiotic use and MRSA rates and the use of veterinary antibiotics. Methods: This study used Europe-wide surveillance data on infectious diseases (EARS-Net), antibiotic consumption (ESAC-Net), and veterinary medicine (ESVAC)...
2017: Journal of Market Access & Health Policy
https://www.readbyqxmd.com/read/28798188/complete-genome-sequence-of-a-livestock-associated-methicillin-resistant-staphylococcus-aureus-sequence-type-5-isolate-from-the-united-states
#2
Samantha J Hau, Darrell O Bayles, David P Alt, Timothy S Frana, Tracy L Nicholson
Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) may be the largest MRSA reservoir outside the hospital setting. One concern with LA-MRSA is the acquisition of novel mobile genetic elements by these isolates. Here, we report the complete genome sequence of a swine LA-MRSA sequence type 5 isolate from the United States.
August 10, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28798187/complete-genome-sequence-of-livestock-associated-methicillin-resistant-staphylococcus-aureus-sequence-type-398-isolated-from-swine-in-the-united-states
#3
Samantha J Hau, Darrell O Bayles, David P Alt, Timothy S Frana, Tracy L Nicholson
Methicillin-resistant Staphylococcus aureus (MRSA) colonizes and causes disease in many animal species. Livestock-associated MRSA (LA-MRSA) isolates are represented by isolates of the sequence type 398 (ST398). These isolates are considered to be livestock adapted. This report provides the complete genome sequence of one swine-associated LA-MRSA ST398 isolate from the United States.
August 10, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28757038/livestock-associated-methicillin-resistant-staphylococcus-aureus-is-widespread-in-farmed-mink-neovison-vison
#4
Julie Elvekjær Hansen, Anders Rhod Larsen, Robert Leo Skov, Mariann Chriél, Gitte Larsen, Øystein Angen, Jesper Larsen, Desireé Corvera Kløve Lassen, Karl Pedersen
Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) clonal complex (CC) 398 is widespread in the Danish pig production with around 90% of herds being positive. Since 2009, cases of CC398 LA-MRSA infections in Danish mink farmers have been observed. The objective of the study was to examine the presence of LA-MRSA in farmed mink. The investigation comprised three different sample types 1) clinical samples from carcasses submitted to the laboratory for diagnostic examination, 2) paws and pharyngeal swabs from healthy animals collected at pelting, and 3) feed samples from mink feed producers...
August 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28749335/evaluation-of-a-widely-used-culture-based-method-for-detection-of-livestock-associated-meticillin-resistant-staphylococcus-aureus-mrsa-denmark-and-norway-2014-to-2016
#5
Jesper Larsen, Marianne Sunde, Md Zohorul Islam, Anne Margrete Urdahl, Aina Steihaug Barstad, Anders Rhod Larsen, Carl Andreas Grøntvedt, Øystein Angen
We evaluated a widely used culture-based method for detection of livestock-associated meticillin-resistant Staphylococcus aureus (LA-MRSA) in samples collected from pigs and the environment inside pig stables in Denmark and Norway. Selective enrichment in tryptic soy broth containing cefoxitin and aztreonam led to a high ratio of false-negative results (26%; 57/221). On this basis, we recommend reconsidering the use of selective enrichment for detection of LA-MRSA in animal and environmental samples.
July 13, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28706213/transmission-of-highly-virulent-community-associated-mrsa-st93-and-livestock-associated-mrsa-st398-between-humans-and-pigs-in-australia
#6
S Sahibzada, S Abraham, G W Coombs, S Pang, M Hernández-Jover, D Jordan, J Heller
Pigs have been recognised as a reservoir of livestock associated methicillin-resistant Staphylococcus aureus (LA-MRSA) in Europe, Asia and North America. However, little is known about the presence and distribution of MRSA in the Australian pig population and pig industry. This study describes the presence, distribution and molecular characteristics of the human adapted Australian CA-MRSA ST93 isolated from pigs, people, and the environment within a piggery. Isolates were subjected to antibiotic susceptibility testing, DNA microarray, whole genome sequencing, multi locus sequence typing, virulence and resistance gene characterization and phylogenetic analysis...
July 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28600216/molecular-epidemiology-and-antibiotic-resistance-of-methicillin-resistant-staphylococcus-aureus-circulating-in-the-russian-federation
#7
Vladimir Gostev, Alexander Kruglov, Olga Kalinogorskaya, Olga Dmitrenko, Olga Khokhlova, Tatsuo Yamamoto, Yuri Lobzin, Irina Ryabchenko, Sergey Sidorenko
The aim of this study was to investigate the patterns of antimicrobial resistance and molecular features of methicillin-resistant Staphylococcus aureus (MRSA) isolates in Russia. Isolates recovered from hospital patients (n=480), healthy medical personnel (n=25), and healthy carriers (n=13) were included in the study. Hospital-acquired MRSA (HA-MRSA) demonstrated high resistance to ciprofloxacin, gentamicin, and chloramphenicol (76%-92%), moderate - to tetracycline, erythromycin, clindamycin, and rifampicin (38%-54%), and low - to fusidic acid, co-trimoxazole, mupirocin, and daptomycin (2%-7%)...
June 7, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28596409/draft-genome-sequence-of-a-sequence-type-398-methicillin-resistant-staphylococcus-aureus-isolate-from-a-danish-dairy-cow-with-mastitis
#8
Troels Ronco, Marc Stegger, Karl Pedersen
Livestock-associated (LA) methicillin-resistant Staphylococcus aureus (MRSA) strains of sequence type 398 (ST398) colonize both humans and various livestock species. In 2016, an ST398 LA-MRSA isolate (Sa52) was collected from a Danish dairy cow with mastitis, and here, we report the draft genome sequence of strain Sa52.
June 8, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28575216/emergence-of-livestock-associated-methicillin-resistant-staphylococcus-aureus-bloodstream-infections-in-denmark
#9
Jesper Larsen, Andreas Petersen, Anders R Larsen, Raphael N Sieber, Marc Stegger, Anders Koch, Frank M Aarestrup, Lance B Price, Robert L Skov
Background: Livestock-associated methicillin-resistant Staphylococcus aureus clonal complex 398 (LA-MRSA CC398) is causing an increasing number of skin and soft tissue infections (SSTIs) in Denmark and other European countries with industrial pig production. Yet, its impact on MRSA bloodstream infections (BSIs) has not been well studied. Methods: We investigated the clinical epidemiology of all human cases of LA-MRSA CC398 BSI during 2010-2015. Cases of LA-MRSA CC398 BSI were compared to cases of BSI caused by other types of MRSA and cases of SSTI caused by LA-MRSA CC398...
May 30, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28567211/methicillin-resistant-staphylococcus-aureus-not-detected-in-swedish-nucleus-and-multiplying-pig-herds
#10
Helle Ericsson Unnerstad, Helene Wahlström, Benedicta Molander, Björn Bengtsson
Introduction: Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) has emerged among pigs in many countries. MRSA in the pig population constitute a reservoir with risk for transmission to humans in close contact with pigs. Absence of MRSA in the top of the breeding pyramid would prevent spread to the rest of the pig population. The aim of this study was to investigate the occurrence of MRSA in nucleus and multiplying pig herds in Sweden. Materials and methods: All nucleus and multiplying pig herds in Sweden present in 2011 (n = 53) and 2014 (n = 39) were sampled for MRSA...
2017: Infection Ecology & Epidemiology
https://www.readbyqxmd.com/read/28526788/zinc-resistance-within-swine-associated-methicillin-resistant-staphylococcus-aureus-isolates-in-the-united-states-is-associated-with-multilocus-sequence-type-lineage
#11
Samantha J Hau, Timothy Frana, Jisun Sun, Peter R Davies, Tracy L Nicholson
Zinc resistance in livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) sequence type 398 (ST398) is primarily mediated by the czrC gene colocated with the mecA gene, encoding methicillin resistance, within the type V staphylococcal cassette chromosome mec (SCCmec) element. Because czrC and mecA are located within the same mobile genetic element, it has been suggested that the use of zinc in feed as an antidiarrheal agent has the potential to contribute to the emergence and spread of methicillin-resistant S...
August 1, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28495772/complete-genome-sequence-of-the-livestock-associated-methicillin-resistant-strain-staphylococcus-aureus-subsp-aureus-08s00974-sequence-type-398
#12
Olga Makarova, Paul Johnston, Birgit Walther, Jens Rolff, Uwe Roesler
We report here the complete genome sequence of the livestock-associated methicillin-resistant Staphylococcus aureus strain 08S00974 from sequence type 398 (ST398 LA-MRSA) isolated from a fatting pig at a farm in Germany.
May 11, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28495466/methicillin-resistant-staphylococcus-aureus-screening-pcr-adapted-to-locally-emerging-variants-evaluation-of-novel-sccmec-primers
#13
Miriam Herma, Sabine Petersdorf, Birgit Henrich
Infections with multi-resistant bacteria, such as Methicillin-resistant Staphylococcus aureus (MRSA), represent a world-wide health-care problem. The original MRSA Screening TaqMan PCR was based on the detection of the SCCmec-orfX-junction as described by the group of Huletsky in 2004. In the recent years, this assay increasingly failed to detect new MRSA variants in swab specimens. In this work, we analyzed the usefulness of 17 additional SCCmec primers to increase PCR sensitivity by testing 290 collected samples with negative PCR results and positive MRSA culture in a retrospective analysis, and 380 samples of the daily routine diagnostics...
June 2017: International Journal of Medical Microbiology: IJMM
https://www.readbyqxmd.com/read/28435193/can-methicillin-resistant-staphylococcus-aureus-prevalence-from-dairy-cows-in-india-act-as-potential-risk-for-community-associated-infections-a-review
#14
REVIEW
Sathish Gopal, Kurunchi C Divya
Methicillin-resistant Staphylococcus aureus (MRSA) is classified as hospital associated (HA), community associated (CA), livestock associated (LA) and is a global concern. Developing countries, like India, are densely populated country challenging for public hygiene practices. HA-MRSA is comfortably recorded in India, and CA-MRSA is also reported as increasing one. CA-MRSA is serious disease which affects the community as endemic. MRSA is one among major mastitis-causing organisms in India as LA-MRSA. There were reports for transmission of MRSA as community between milk handlers and cow in global perspective...
March 2017: Veterinary World
https://www.readbyqxmd.com/read/28431450/-livestock-associated-methicillin-resistant-staphylococcus-aureus-epidemiological-data-from-an-orthopaedic-department-in-north-west-germany
#15
Gerrit Steffen Maier, Fritz Thorey, Kristina Kolbow, Djordje Lazovic, Markus Lühmann, Jörg Ohnsorge, Uwe Maus
Background MRSA represents a considerable health threat to orthopaedic patients. Throughout the last decade, livestock-associated MRSA emerged increasingly in livestock all over Europe. LA-MRSA broke the species barrier, colonizing and causing infections in humans. Nevertheless, to date there are no studies concerning livestock-associated MRSA and orthopaedic patients. Therefore, we aimed to investigate the prevalence of LA-MRSA in a regional orthopaedic department localized in an area with high-density livestock...
June 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28351443/phenotypic-and-molecular-characteristics-of-staphylococcus-aureus-and-methicillin-resistant-staphylococcus-aureus-in-slaughterhouse-pig-related-workers-and-control-workers-in-guangdong-province-china
#16
X L Wang, L Li, S M Li, J Y Huang, Y P Fan, Z J Yao, X H Ye, S D Chen
Pig farmers and veterinarians have high prevalence of methicillin-resistant Staphylococcus aureus (MRSA) due to the occupational livestock exposure, while few reported this association on slaughterhouse workers. We conducted this cross-sectional study to explore the phenotypic and molecular characteristics of S. aureus and MRSA in slaughterhouse pig-related workers and control workers in Guangdong Province, China. Participants were interviewed and provided two nasal swabs. Swabs were tested for S. aureus, and isolates were further tested for antimicrobial susceptibility, virulence genes and multi-locus sequence typing...
July 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28348878/a-phylogenomic-framework-for-assessing-the-global-emergence-and-evolution-of-clonal-complex-398-methicillin-resistant-staphylococcus-aureus
#17
Anders Gonçalves da Silva, Sarah L Baines, Glen P Carter, Helen Heffernan, Nigel P French, Xiaoyun Ren, Torsten Seemann, Dieter Bulach, Jason Kwong, Timothy P Stinear, Benjamin P Howden, Deborah A Williamson
Distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) have emerged as important causes of infection in individuals who have exposure to livestock (livestock-associated MRSA; LA-MRSA). Clonal complex 398 (CC398) is the most prevalent LA-MRSA clone, and has been reported from several geographical settings, including Europe, the Americas and Asia. To understand the factors contributing to the global dissemination of this clone, we analysed CC398 MRSA isolates from New Zealand (NZ), a geographically isolated country with an economy strongly dependent on livestock farming...
January 2017: Microbial Genomics
https://www.readbyqxmd.com/read/28324679/methicillin-resistant-and-susceptible-staphylococcus-aureus-from-retail-meat-in-denmark
#18
Yuanyue Tang, Jesper Larsen, Jette Kjeldgaard, Paal Skytt Andersen, Robert Skov, Hanne Ingmer
Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) is increasingly related to human infections. Farmers and veterinarians have the highest risk, but infections have also occurred in individuals without prior contact to livestock. Clonal complex (CC) 398 is the predominant LA-MRSA lineage causing human infections, and although pigs are the major source of CC398 worldwide, poultry and other animals are also reservoirs. This raises concern for transmission of MRSA via meat. In this study, the occurrence and characteristics of S...
March 6, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28304109/methicillin-resistant-staphylococcus-aureus-a-controversial-food-borne-pathogen
#19
REVIEW
D Sergelidis, A S Angelidis
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of severe healthcare-associated (HA) infections. Although during the last decade the incidence of HA invasive infections has dropped, the incidence of community-associated MRSA (CA-MRSA) infections has risen among the general population. Moreover, CA-MRSA, livestock-associated MRSA (LA-MRSA) and HA-MRSA (HA-MRSA) can be found in foods intended for human consumption. Several studies from different geographical areas have reported the presence of enterotoxin genes in several MRSA food isolates...
June 2017: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/28284852/current-methodologies-on-genotyping-for-nosocomial-pathogen-methicillin-resistant-staphylococcus-aureus-mrsa
#20
REVIEW
Jian Miao, Lequn Chen, Jingwen Wang, Wenxin Wang, Dingqiang Chen, Lin Li, Bing Li, Yang Deng, Zhenbo Xu
Methicillin-resistant Staphylococcus aureus (MRSA) is a common pathogen in hospitals and the community. As the rapid spread and wide distribution of antimicrobial resistance (such as MRSA), treatment for infectious diseases caused by microorganisms has become a vital threat. Thus, early identification and genotyping are essential for further therapeutic treatment and the control of rapid expansion of MRSA. In combination with applications and data feedbacks, this review focused on the currently available molecular-based assays on their utility and performance for rapid typing of MRSA, especially on effective molecular-based methods...
March 9, 2017: Microbial Pathogenesis
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