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https://www.readbyqxmd.com/read/29792764/use-of-a-depression-and-sleep-impairment-treatment-guideline-to-improve-quality-of-life-for-patients-with-sickle-cell-disease
#1
Sheran M Simo, Debra Siela
BACKGROUND: Pain in sickle cell disease (SCD) is often joined by other affective disorders such as depression and/or sleep impairment that can impact pain levels and quality of life (QoL). AIM: To develop a guideline to improve the process of assessment and treatment of depression and sleep impairment in patients admitted with SCD. METHOD: An interdisciplinary team used the Stetler model to create the Guideline for the Evaluation and Treatment of Depression and Sleep Impairment in Sickle Cell Disease...
May 2, 2018: International Journal of Palliative Nursing
https://www.readbyqxmd.com/read/29792585/assessment-in-work-productivity-and-the-relationship-with-cognitive-symptoms-atworc-primary-analysis-from-a-canadian-open-label-study-of-vortioxetine-in-patients-with-major-depressive-disorder-mdd
#2
Pratap Chokka, Joanna Bougie, Emmanouil Rampakakis, Jean Proulx
OBJECTIVE: The Assessment in Work Productivity and the Relationship with Cognitive Symptoms (AtWoRC) study aimed to assess the association between cognitive symptoms and work productivity in gainfully employed patients receiving vortioxetine for a major depressive episode (MDE). METHODS: Patients diagnosed with major depressive disorder (MDD) and treated with vortioxetine independently of study enrollment were assessed over 52 weeks at visits that emulated a real-life setting...
May 24, 2018: CNS Spectrums
https://www.readbyqxmd.com/read/29792241/efficacy-of-digital-cbt-for-insomnia-to-reduce-depression-across-demographic-groups-a-randomized-trial
#3
Philip Cheng, Annemarie I Luik, Cynthia Fellman-Couture, Edward Peterson, Christine L M Joseph, Gabriel Tallent, Kieulinh Michelle Tran, Brian K Ahmedani, Timothy Roehrs, Thomas Roth, Christopher L Drake
BACKGROUND: Insomnia and depression are highly comorbid and mutually exacerbate clinical trajectories and outcomes. Cognitive behavioral therapy for insomnia (CBT-I) effectively reduces both insomnia and depression severity, and can be delivered digitally. This could substantially increase the accessibility to CBT-I, which could reduce the health disparities related to insomnia; however, the efficacy of digital CBT-I (dCBT-I) across a range of demographic groups has not yet been adequately examined...
May 24, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29792234/long-term-outcomes-of-acute-treatment-with-cognitive-therapy-v-interpersonal-psychotherapy-for-adult-depression-follow-up-of-a-randomized-controlled-trial
#4
Lotte H J M Lemmens, Suzanne C van Bronswijk, Frenk Peeters, Arnoud Arntz, Steven D Hollon, Marcus J H Huibers
BACKGROUND: Although equally efficacious in the acute phase, it is not known how cognitive therapy (CT) and interpersonal psychotherapy (IPT) for major depressive disorder (MDD) compare in the long run. This study examined the long-term outcomes of CT v. IPT for MDD. METHODS: One hundred thirty-four adult (18-65) depressed outpatients who were treated with CT (n = 69) or IPT (n = 65) in a large open-label randomized controlled trial (parallel group design; computer-generated block randomization) were monitored across a 17-month follow-up phase...
May 24, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29792226/treatment-of-depression-and-or-anxiety-outcomes-of-a-randomised-controlled-trial-of-the-tree-theme-method%C3%A2-versus-regular-occupational-therapy
#5
A Birgitta Gunnarsson, Petra Wagman, Katarina Hedin, Carita Håkansson
BACKGROUND: Depression and anxiety disorders are a major concern in western countries, and because these often have a negative affect on everyday life interventions based on activities in everyday life are needed. The Tree Theme Method® (TTM) is a client-centred occupational therapy intervention designed to increase the ability to cope with, and to enhance satisfaction with, everyday life, both at home and at work. The aim of this study was to compare the short term outcomes of the TTM intervention with regular occupational therapy treatment for people with depression and/or anxiety disorders...
May 23, 2018: BMC Psychology
https://www.readbyqxmd.com/read/29792195/histamine-activates-inflammatory-response-and-depresses-casein-synthesis-in-mammary-gland-of-dairy-cows-during-sara
#6
Guangjun Chang, Lailai Wang, Nana Ma, Wenwen Zhang, Huanmin Zhang, Hongyu Dai, Xiangzhen Shen
BACKGROUND: Mounting evidences observed that subacute ruminal acidosis (SARA) induced by high concentration (HC) diet increases the translocation of histamine from digestive tract into circulation causing a diverse of diseases in dairy cows. However, it is largely unknown how it does affect the function of mammary gland and milk quality. Hence, this study aims to observe the effects of histamine derived from the digestive tract on the inflammatory response and casein synthesis in the mammary glands during SARA...
May 23, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29792188/health-related-quality-of-life-in-multiple-sclerosis-temperament-outweighs-edss
#7
S Salhofer-Polanyi, F Friedrich, S Löffler, P S Rommer, A Gleiss, R Engelmaier, F Leutmezer, B Vyssoki
BACKGROUND: The influence of personality on health-related quality of life in patients with multiple sclerosis has been the focus of previous studies showing that introversion and neuroticism were related with reduced health related quality of life. However, no data exist on the impact of temperament on quality of life in this patient group. METHODS: Between April 2014 and March 2016 139 multiple sclerosis patients were recruited from a specialized outpatient clinic of the general hospital of Vienna...
May 23, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29792087/effects-of-intensive-short-term-dynamic-psychotherapy-on-social-cognition-in-major-depression
#8
Bita Ajilchi, Steve Kisely, Vahid Nejati, Jon Frederickson
BACKGROUND: Social cognition is commonly affected in psychiatric disorders and is a determinant of quality of life. However, there are few studies of treatment. OBJECTIVE: To investigate the efficacy of intensive short-term dynamic psychotherapy on social cognition in major depression. METHOD: This study used a parallel group randomized control design to compare pre-test and post-test social cognition scores between depressed participants receiving ISTDP and those allocated to a wait-list control group...
May 23, 2018: Journal of Mental Health
https://www.readbyqxmd.com/read/29792050/risk-of-psychosis-in-recurrent-episodes-of-psychotic-and-nonpsychotic-major-depressive-disorder-a-systematic-review-and-meta-analysis
#9
J Craig Nelson, David Bickford, Kevin Delucchi, Jess G Fiedorowicz, William H Coryell
OBJECTIVE: The authors conducted a systematic review and meta-analysis to determine whether the risk of psychosis is higher in past or future episodes in patients with major depression with psychotic features than in patients with nonpsychotic depression. METHOD: PubMed, Embase, and PsycINFO were searched, and studies were selected that 1) identified patients with unipolar major depression, 2) made diagnoses of psychosis based on the presence of delusions or hallucinations, 3) characterized past or subsequent episodes as psychotic or nonpsychotic, and 4) were published in English...
May 24, 2018: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29791945/global-health-epilepsy
#10
Amza Ali
Epilepsy is a frequently misunderstood and highly stigmatized condition. Major treatment gaps exist across the world, most so in areas of financial constraint. Classification permits the best approaches to treatment and to ascertaining prognosis. The International League Against Epilepsy's new classification system emphasizes clinical aspects and utilizes all available resources to determine whether it is a focal or generalized epilepsy. The most important tools are a careful history, clinical examination, electroencephalography, and appropriate neuroimaging...
April 2018: Seminars in Neurology
https://www.readbyqxmd.com/read/29791718/alopecia-areata-a-review-of-disease-pathogenesis
#11
REVIEW
F Rajabi, L A Drake, M M Senna, N Rezaei
Alopecia areata is a disorder that results in non-scarring hair loss. The psychological impact can be significant, leading to feelings of depression and social isolation. The disease remains incurable though it has been studied for years. Available treatment options at best, are beneficial for milder cases, and the rate of relapse is high. Understanding the exact mechanisms of hair loss in alopecia areata is therefore of utmost importance to help identify potential therapeutic targets. The main theory of alopecia areata pathogenesis is that it is an autoimmune phenomenon resulting from a disruption in hair follicle immune privilege...
May 23, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29791588/microrna-451a-microrna-34a-5p-and-microrna-221-3p-as-predictors-of-response-to-antidepressant-treatment
#12
Wei-Hong Kuang, Zai-Quan Dong, Lian-Tian Tian, Jin Li
Aberrant expression of microRNAs (miRNAs) has been shown to be involved in early observations of depression. The aim of this study was to determine if serum levels of miRNA-451a, miRNA-34a-5p, and miRNA-221-3p can serve as indicators of disease progression or therapeutic efficacy in depression. We collected data from 84 depressed patients and 78 control volunteers recruited from the medical staff at the West China Hospital. Depression severity was rated using the 24-item Hamilton Depression Scale (HAMD). Serum miRNA-451a, miRNA-34a-5p, and miRNA-221-3p levels were determined in samples from the depressed patients before and 8 weeks after antidepressant treatment as well as in samples from controls...
2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/29791247/a-randomized-trial-of-a-family-support-intervention-in-intensive-care-units
#13
Douglas B White, Derek C Angus, Anne-Marie Shields, Praewpannarai Buddadhumaruk, Caroline Pidro, Cynthia Paner, Elizabeth Chaitin, Chung-Chou H Chang, Francis Pike, Lisa Weissfeld, Jeremy M Kahn, Joseph M Darby, Amy Kowinsky, Susan Martin, Robert M Arnold
Background Surrogate decision makers for incapacitated, critically ill patients often struggle with decisions related to goals of care. Such decisions cause psychological distress in surrogates and may lead to treatment that does not align with patients' preferences. Methods We conducted a stepped-wedge, cluster-randomized trial involving patients with a high risk of death and their surrogates in five intensive care units (ICUs) to compare a multicomponent family-support intervention delivered by the interprofessional ICU team with usual care...
May 23, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29791193/shame-and-interpersonal-sensitivity-gender-differences-and-the-association-between-internalized-shame-coping-strategies-and-interpersonal-sensitivity
#14
Markus B T Nyström, Emilie Kjellberg, Ulrica Heimdahl, Bert Jonsson
The present study investigated gender differences in interpersonal sensitivity and internalized shame coping strategies in 252 undergraduate students. To measure interpersonal sensitivity and shame coping strategies, the self-assessment forms Interpersonal Sensitivity Measure and Compass of Shame Scale were used. The analyses revealed that compared to men, women display interpersonal sensitivity to a higher degree, and they use internalized shame coping strategies to a greater extent. The results also showed that interpersonal sensitivity is highly correlated with shame coping strategies...
2018: Bulletin of the Menninger Clinic
https://www.readbyqxmd.com/read/29790850/-the-practical-considerations-of-antidepressant-use-during-pregnancy-and-breastfeeding
#15
Peter Dome, Gabor Faludi
Main indications of antidepressants (ADs) as major depressive disorder (MDD) and different kinds of anxiety disorders are quite prevalent during pregnancy and the postpartum period. Due to the possible hazards of in utero and breast milk exposition of ADs, both psychiatrists and mothers frequently have concerns about the use of ADs during the periods of pregnancy and breastfeeding. However, we should also bear in mind that affective disorders left untreated during these periods are also associated with health risks for the mother and the baby as well...
March 2018: Neuropsychopharmacologia Hungarica
https://www.readbyqxmd.com/read/29790568/-social-cognition-and-cognitive-functions-in-patients-with-epilepsy-treated-with-eslicarbazepine-acetate
#16
L Abraira, A Sanabria, G Ortega, M Quintana, E Santamarina, J Salas-Puig, M Toledo
INTRODUCTION: Epilepsy is accompanied by cognitive disorders, frequently aggravated by the use of antiepileptic drugs, which can affect social empathy. AIM: To analyse the impact of treatment with eslicarbazepine acetate (ESL) on social cognition and prefrontal cognitive functions in adults with focal epilepsy. PATIENTS AND METHODS: We conducted a prospective single-centre study with patients aged between 18 and 65 years with focal seizures treated with ESL...
June 1, 2018: Revista de Neurologia
https://www.readbyqxmd.com/read/29790360/-current-and-future-pharmacotherapy-of-severe-psychiatric-disorders
#17
Eva Češková
Despite of tremendous development in CNS research, current treatment is suboptimal especially in severe mental disorders. In medicine, there are two main methods of improving the healthcare provided: seeking new treatment procedures and perfecting (optimizing) the existing ones. Optimization of treatment includes not only practical tools such as therapeutic drug monitoring, but also implementation of general trends into the clinical practice. New pharmacological options include drugs aimed at other than monoaminergic systems and old drugs used before the psychopharmacological era...
2018: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/29790135/-spiritual-care-of-patients-with-depression
#18
Chia-Chan Kao, Yu-Hua Lin
Spiritual care is a component of holistic care. Patients with depression often experience body-mind-spirit health problems and may suffer from spiritual crises, particularly during the acute stage of a diseases, due to low self-esteem, negative attitudes toward life goals, daily life issues, and beliefs caused by physical, psychological, and occupational dysfunctions. Nonetheless, psychical care is the main treatment for patients with depression. This paper focuses on patients with depression and addresses the concepts of spiritual needs and spiritual care, identifying the factors that influence spiritual needs, the essentials of spiritual intervention, and the health effects of spiritual intervention outcomes on patients with depression...
June 2018: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/29789774/pilot-study-of-dose-response-effects-of-exercise-on-change-in-c-reactive-protein-cortisol-and-health-related-quality-of-life-among-cancer-survivors
#19
Jeanette M Ricci, Victoria Flores, Isabela Kuroyama, Arash Asher, Heather P Tarleton
Fatigue, stress, and depression contribute to poor health-related quality of life (HRQoL) among cancer survivors. This study examined the effects of combined aerobic and resistance training (CART) on HRQoL and biomarkers of stress. Cancer survivors ( n  = 76, 91% female, 39% breast cancer, 32% gynecologic cancer) were enrolled in CART for three 60-min sessions, weekly, for 26 weeks. Participants completed the National Institutes of Health's Patient Reported Outcomes Measurement Information System (NIH PROMIS) fatigue assessment and the SF-36...
2018: BioResearch Open Access
https://www.readbyqxmd.com/read/29789247/preoperative-depression-is-negatively-associated-with-function-and-predicts-poorer-outcomes-after-hip-arthroscopy-for-femoroacetabular-impingement
#20
Kyle R Sochacki, Lindsey Brown, Kathleen Cenkus, Stephanie Di Stasi, Joshua D Harris, Thomas J Ellis
PURPOSE: (1) To determine the prevalence of depression in patients undergoing hip arthroscopy for the treatment of femoroacetabular impingement (FAI) syndrome and (2) to determine whether depression has a statistically significant and clinically relevant effect on preoperative and postoperative patient-reported outcome scores. METHODS: Consecutive subjects undergoing hip arthroscopy for FAI syndrome were retrospectively reviewed. The Beck Depression Inventory-II (BDI-II), Hip Outcome Score (HOS), and 33-item International Hip Outcome Tool (iHOT-33) were administered preoperatively and postoperatively...
May 19, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
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