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https://www.readbyqxmd.com/read/28742757/concurrent-validity-and-responsiveness-of-promis-health-domains-among-patients-presenting-for-anterior-cervical-spine-surgery
#1
Taylor E Purvis, Elena Andreou, Brian J Neuman, Lee H Riley, Richard L Skolasky
STUDY DESIGN: Prospective cohort study. OBJECTIVE: To determine validity and responsiveness of Patient-Reported Outcomes Measurement Information System (PROMIS) health domains. SUMMARY OF BACKGROUND DATA: PROMIS health domains (anxiety, depression, fatigue, pain, physical function, satisfaction with participation in social roles, sleep disturbance) may measure quality of care and determine minimal important differences (MIDs) after spine surgery...
July 24, 2017: Spine
https://www.readbyqxmd.com/read/28742505/effects-of-a-hops-humulus-lupulus-l-dry-extract-supplement-on-self-reported-depression-anxiety-and-stress-levels-in-apparently-healthy-young-adults-a-randomized-placebo-controlled-double-blind-crossover-pilot-study
#2
Ioannis Kyrou, Aimilia Christou, Demosthenes Panagiotakos, Charikleia Stefanaki, Katerina Skenderi, Konstantina Katsana, Constantine Tsigos
OBJECTIVE: The Humulus lupulus L. plant (hops) is used as a herbal medicinal product for anxiety/mood disorders. Our aim was to study the effects of a hops dry extract on self-reported depression, anxiety and stress levels in young adults. DESIGN: Apparently healthy young adults from our university completed the Depression Anxiety Stress Scale-21 (DASS-21) and those reporting at least mild depression, anxiety and stress were invited to complete the study intervention...
April 2017: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28742418/health-risk-behavior-among-justice-involved-male-and-female-youth-exploratory-multi-group-latent-class-analysis
#3
Richard Dembo, Jessica Faber, Jennifer Cristiano, Ralph J DiClemente, Julie M Krupa, Asha Terminello, Jennifer Wareham
BACKGROUND: Youth involved in the juvenile justice system experience a disproportionate prevalence of serious mental health issues, substance abuse, and are at an increased risk of engaging in risky sexual practices. Gender differences exist, with girls at a markedly greater risk of acquiring a sexually transmitted disease. OBJECTIVES: The present study seeks to determine if there are subgroups of male and female youth who differ in their health risk behavior. If so, do any male or female subgroups at different levels of health risk differ in regard to their sociodemographic and psychological factors, and finally, what are intervention/service delivery implications of these differences...
July 25, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28742411/is-major-depression-linked-to-alcohol-impaired-driving
#4
Ye Z Pogue, Jahn K Hakes, Frank A Sloan
BACKGROUND: Alcohol-impaired driving causes a substantial proportion of motor vehicle accidents. Depression is a prevalent psychiatric disorder among drinker-drivers. Few previous studies have investigated the relationship between major depression and alcohol-impaired driving. OBJECTIVES: We investigated whether depression has a positive relationship with the probability of alcohol-impaired driving after controlling for the co-occurrence of binge drinking and alcohol dependence...
July 25, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28742406/the-efficacy-of-low-dose-tadalafil-in-patients-undergoing-hemodialysis-with-end-stage-renal-disease
#5
Mustafa Suat Bolat, İsmail Özer, Onder Cinar, Ekrem Akdeniz, Ramazan Aşcı
BACKGROUND: Erectile dysfunction (ED) is a disorder that is frequently observed in people with chronic kidney disease who undergo hemodialysis (HD). In the context of evidence-based medicine, we aimed to investigate the effect of low-dose tadalafil on sexual function in patients undergoing HD. METHODS: The medical records of 30 males (aged 29-65 years) with end-stage renal disease (ESRD) on a HD program, and who had received 5 mg tadalafil twice weekly, were retrospectively evaluated...
November 2017: Renal Failure
https://www.readbyqxmd.com/read/28742292/effects-of-a-course-of-right-unilateral-ultrabrief-pulse-electroconvulsive-therapy-combined-with-venlafaxine-on-insomnia-symptoms-in-elderly-depressed-patients
#6
W Vaughn McCall, Sarah H Lisanby, Peter B Rosenquist, Mary Dooley, Mustafa M Husain, Rebecca G Knapp, Georgios Petrides, Matthew V Rudorfer, Robert C Young, Shawn M McClintock, Martina Mueller, Joan Prudic, Robert M Greenberg, Richard D Weiner, Samuel H Bailine, Mary Anne Riley, Laryssa McCloud, Charles H Kellner
OBJECTIVE: Antidepressant medications have a variety of effects on sleep, apart from their antidepressant effects. It is unknown whether electroconvulsive therapy (ECT) has effects on perceived sleep in depressed patients. This secondary analysis examines the effects of ECT on perceived sleep, separate from its antidepressant effects. METHODS: Elderly patients with major depressive disorder, as defined by DSM-IV, received open-label high-dose, right unilateral ultrabrief pulse ECT, combined with venlafaxine, as part of participating in phase 1 of the National Institute of Mental Health-supported study Prolonging Remission in Depressed Elderly (PRIDE)...
July 18, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28741670/intensive-cognitive-therapy-for-post-traumatic-stress-disorder-in-routine-clinical-practice-a-matched-comparison-audit
#7
Hannah Murray, Sharif El-Leithy, Jo Billings
OBJECTIVES: Intensive cognitive therapy for post-traumatic stress disorder (PTSD) has been shown to be as effective as weekly treatment in controlled trials. In this study, outcome data comparing standard and intensive treatments delivered in routine clinical practice were analysed. METHODS: A consecutive case series of intensive treatment cases were compared to matched control cases who had completed weekly treatment. RESULTS: Both groups showed significant improvements on PTSD and depression measures...
July 25, 2017: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28741646/aggressiveness-in-depression-a-neglected-symptom-possibly-associated-with-bipolarity-and-mixed-features
#8
N Verdolini, G Perugi, L Samalin, A Murru, J Angst, J-M Azorin, C L Bowden, S Mosolov, A H Young, M Barbuti, G Guiso, D Popovic, E Vieta, I Pacchiarotti
OBJECTIVE: To evaluate aggressiveness during a major depressive episode (MDE) and its relationship with bipolar disorder (BD) in a post hoc analysis of the BRIDGE-II-MIX study. METHOD: A total of 2811 individuals were enrolled in this multicenter cross-sectional study. MDE patients with (MDE-A, n = 399) and without aggressiveness (MDE-N, n = 2412) were compared through chi-square test or Student's t-test. A stepwise backward logistic regression model was performed...
July 25, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28741624/hormonal-cycle-and-contraceptive-effects-on-amygdala-and-salience-resting-state-networks-in-women-with-previous-affective-side-effects-on-the-pill
#9
Jonas Engman, Inger Sundström Poromaa, Lena Moby, Johan Wikström, Mats Fredrikson, Malin Gingnell
The mechanisms linking ovarian hormones to negative affect are poorly characterized, but important clues may come from the examination of the brain's intrinsic organization. Here, we studied the effects of both the menstrual cycle and oral contraceptives (OCs) on amygdala and salience network resting-state functional connectivity using a double-blind, randomized, and placebo-controlled design. Hormone levels, depressive symptoms, and resting-state functional connectivity were measured in 35 healthy women (24...
July 25, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28741044/efficacy-and-tolerability-of-asenapine-compared-with-olanzapine-in-borderline-personality-disorder-an-open-label-randomized-controlled-trial
#10
Paola Bozzatello, Paola Rocca, Maria Uscinska, Silvio Bellino
BACKGROUND: Asenapine is a new second-generation antipsychotic that is understudied in borderline personality disorder (BPD). Only one study investigating the use of the drug in this indication (an open-label pilot study) has been conducted to date. OBJECTIVE: The present open-label, randomized, controlled trial aimed to evaluate the efficacy and tolerability of asenapine in comparison with olanzapine, the most broadly studied antipsychotic in BPD. METHODS: A total of 51 outpatients aged between 18 and 50 years with a diagnosis of BPD based on Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria were assigned for 12 weeks to asenapine (5-10 mg/day) or olanzapine (5-10 mg/day)...
July 24, 2017: CNS Drugs
https://www.readbyqxmd.com/read/28741010/perception-of-a-single-session-pre-in-vitro-fertilisation-counselling-service-and-attitudes-towards-support-group-a-survey-of-patients-in-singapore
#11
Gaik Suan Lim, Reshmi Karayan Kayanoth, Birit Fp Broekman, Cornelia Yi Chee
INTRODUCTION: This study aimed to investigate patients' evaluation of a compulsory pre-in vitro fertilisation (IVF) counselling session in Singapore and determine their attitudes towards attending a support group during IVF treatment. METHODS: 464 patients due to undergo their first IVF treatment were recruited at the Clinic for Human Reproduction, National University Hospital, Singapore. All patients attended a counselling session conducted by a clinical psychologist trained in infertility counselling prior to IVF treatment...
July 25, 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28740827/self-versus-informant-reports-on-the-specific-levels-of-functioning-scale-relationships-to-depression-and-cognition-in-schizophrenia-and-schizoaffective-disorder
#12
Julia Ermel, Cameron S Carter, James M Gold, Angus W MacDonald, J Daniel Ragland, Steven M Silverstein, Milton E Strauss, Deanna M Barch
The goal of the current study was to examine the relationships between insight and both cognitive function and depression in schizophrenia and schizoaffective disorder, and to determine if there were similar relationships across diagnostic categories. We examined discrepancies between self and informant reports of function on the Specific levels of function scale as a metric of insight for interpersonal, social acceptance, work and activities. We examined two samples of individuals with schizophrenia and/or schizoaffective disorder (Ns of 188 and 67 respectively)...
September 2017: Schizophrenia Research. Cognition
https://www.readbyqxmd.com/read/28740732/low-molecular-weight-ngf-mimetic-corrects-the-cognitive-deficit-and-depression-like-behavior-in-experimental-diabetes
#13
R U Ostrovskaya, S S Yagubova, T A Gudasheva, S B Seredenin
Based on the comorbidity of diabetes, depression, and dementia and recognizing that a deficiency of the nerve growth factor (NGF) is involved in all of these kinds of pathologies, we studied the effect of the mimetic of dimeric dipeptide NGF loop 4, GK-2, on a model of streptozotocin-induced type 2 diabetes in C57Bl/6 mice. GK-2 [hexamethylenediamide bis-(N-monosuccinyl-glutamyl-lysine)] was synthesized at the V.V. Zakusov Scientific Research Institute of Pharmacology. The study revealed the ability of GK-2 to ameliorate hyperglycemia induced by streptozotocine (STZ 100 mg/kg i...
April 2017: Acta Naturae
https://www.readbyqxmd.com/read/28740537/the-anti-inflammatory-effects-of-invigorating-kidney-and-supplementing-qi-chinese-herbal-formulae-in-asthma-patients
#14
Lingwen Kong, Hongying Zhang, Yuxue Cao, Jingjing Le, Jinfeng Wu, Baojun Liu, Meixia Chen, Yijie Du, Jia Wang, Genfa Wang, Tao Yi, Xianmei Zhou, Gang Wang, Qing Miao, Suyun Li, Naiqing Zhao, Jingcheng Dong
BACKGROUND: The theories of Shen-reinforcement and Qi-supplementation are important in asthma treatment based on traditional Chinese medicine theories. Early studies suggested that Invigorating Kidney and Supplementing Qi herbal formulae, Bu Shen Fang Chuan (BSFC) and Bu Shen Yi Qi (BSYQ), conveyed promising results in asthma treatment. However, the efficacy and safety of the formulae need to be further investigated by a randomized double-blind clinical trial. METHODS: 328 eligible patients were randomly sent to BSFC, BSYQ, and placebo group...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28740427/vulvodynia-is-not-created-equally-empirical-classification-of-women-with-vulvodynia
#15
Meryl Alappattu, Georgine Lamvu, Jessica Feranec, Kathryn Witzeman, Michael Robinson, Andrea Rapkin
BACKGROUND: Vulvodynia classification is based on the sensory dimensions of pain and does not include psychological factors associated with the pain experience and treatment outcomes. Previous work has shown that individuals with chronic pain can be classified into subgroups based on pain sensitivity, psychological distress, mood, and symptom severity. OBJECTIVE: The aim of this study was to identify distinct subgroups of women with vulvodynia enrolled in the National Vulvodynia Registry...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28740424/risk-and-protective-factors-in-the-clinical-rehabilitation-of-chronic-back-pain
#16
Pia-Maria Wippert, Michael Fliesser, Matthias Krause
OBJECTIVES: Chronic back pain (CBP) can lead to disability and burden. In addition to its medical causes, its development is influenced by psychosocial risk factors, the so-called flag factors, which are categorized and integrated into many treatment guidelines. Currently, most studies investigate single flag factors, which limit the estimation of individual factor significance in the development of chronic pain. Furthermore, factors concerning patients' lifestyle, biography and treatment history are often neglected...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28740415/the-extracellular-matrix-of-eggshell-displays-anti-inflammatory-activities-through-nf-%C3%AE%C2%BAb-in-lps-triggered-human-immune-cells
#17
Tram T Vuong, Sissel B Rønning, Henri-Pierre Suso, Ralf Schmidt, Kristian Prydz, Marlene Lundström, Anders Moen, Mona E Pedersen
Avian eggshell membrane (ESM) is a natural biomaterial that has been used as an alternative natural bandage on burned and cut skin injuries for >400 years in Asian countries, and is available in large quantities from egg industries. Our aim was to characterize ESM that was separated and processed from egg waste, and to study whether this material possesses anti-inflammatory properties, making it suitable as an ingredient in industrial production of low cost wound healing products. Our results show that the processed ESM particles retain a fibrous structure similar to that observed for the native membrane, and contain collagen, and carbohydrate components such as hyaluronic acid and sulfated glycosaminoglycans, as well as N-glycans, mostly with uncharged structures...
2017: Journal of Inflammation Research
https://www.readbyqxmd.com/read/28739537/differing-antidepressant-maintenance-methodologies
#18
REVIEW
Daniel J Safer
BACKGROUND: The principle evidence that antidepressant medication (ADM) is an effective maintenance treatment for adults with major depressive disorder (MDD) is from placebo substitution trials. These trials enter responders from ADM efficacy trials into randomized, double-blind placebo-controlled (RDBPC) effectiveness trials to measure the rate of MDD relapse over time. However, other randomized maintenance trial methodologies merit consideration and comparison. METHODS: A systematic review of ADM randomized maintenance trials included research reports from multiple databases...
July 21, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28739387/effect-of-cortex-mori-on-pharmacokinetic-profiles-of-main-isoflavonoids-from-pueraria-lobata-in-rat-plasma
#19
Bingxin Xiao, Zeng Xian Sun, Shu Yang Sun, Jie Dong, Yanli Li, Shan Gao, Jie Pang, Qi Chang
ETHNOPHARMACOLOGICAL RELEVANCE: Radix pueraria (the root of pueraria lobata (Wild.) Ohwi.), which contains a class of isoflavonoids as the main active components, as well as cortex mori (the root bark of Morus Alba L), which contains abundant active alkaloids, have been employed for the treatment of diabetes in traditional Chinese medicine for centuries. In previous studies, pharmacodynamic synergistic reactions have been observed in compatible application of pueraria lobata isoflavonoids extracts (PLF) and cortex mori alkaloids extracts (CME) for inhibiting α-glycosidase activity...
July 21, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28739309/preoperative-symptoms-in-femoroacetabular-impingement-patients-are-more-related-to-mental-health-scores-than-the-severity-of-labral-tear-or-magnitude-of-bony-deformity
#20
Cale A Jacobs, Jeremy M Burnham, Kate N Jochimsen, Domingo Molina, David A Hamilton, Stephen T Duncan
BACKGROUND: The purpose of this study was to determine the relationships between patient factors, mental health status, the condition of the local tissue, magnitude of bony deformity, and preoperative symptoms in a series of femoroacetabular impingement (FAI) patients. METHODS: From our prospective outcomes registry, we identified 64 patients with arthroscopically-treated labral tears and cam deformities. We assessed the correlations between patient factors (age, sex, body mass index, level of education), surgical findings (size of labral tear, presence of chondral lesions), mental health factors (VR-12 mental component score [MCS], depression, and preoperative use of psychotropic and/or opioid drugs), magnitude of FAI deformity (alpha and lateral center edge angles), and preoperative hip dysfunction and osteoarthritis outcome score (HOOS) subscales...
July 8, 2017: Journal of Arthroplasty
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