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Tao Liu, Zigeng Liu, Gunwoo Kim, James T Frith, Nuria Garcia-Araez, Clare Grey
Non-aqueous Li-O2 batteries are promising for next generation energy storage. New battery chemistries based on LiOH, rather than Li2O2, have recently been reported in systems with added water, one using a soluble additive LiI and the other using solid Ru catalysts. Here, we focus on the mechanism of Ru-catalyzed LiOH chemistry. Using nuclear magnetic resonance, operando electrochemical pressure measurements and mass spectrometry, we show that on discharging LiOH forms via a 4 e- oxygen reduction reaction, the H in LiOH coming solely from added H2O and the O from both O2 and H2O...
October 23, 2017: Angewandte Chemie
Amit Akirov, Tzipora Shochat, Amir Shechvitz, Ilan Shimon, Talia Diker-Cohen, Eyal Robenshtok
CONTEXT: Limited data is available regarding the association between pre-admission thyroid function and prognosis of hospitalized patients treated for hypothyroidism. OBJECTIVE: Evaluate an association between thyroid stimulating hormone (TSH) levels and mortality in hospitalized levothyroxine-treated patients. DESIGN AND SETTING: Observational data of patients admitted to medical wards between 2011 and 2013. TSH levels obtained up to 180 days prior to admission were stratified as follows: low (≤0...
October 20, 2017: Endocrine
G Troy Smith, Melissa R Proffitt, Adam R Smith, Douglas B Rusch
Sexually dimorphic behaviors are often regulated by androgens and estrogens. Steroid receptors and metabolism are control points for evolutionary changes in sexual dimorphism. Electric communication signals of South American knifefishes are a model for understanding the evolution and physiology of sexually dimorphic behavior. These signals are regulated by gonadal steroids and controlled by a simple neural circuit. Sexual dimorphism of the signals varies across species. We used transcriptomics to examine mechanisms for sex differences in electric organ discharges (EODs) of two closely related species, Apteronotus leptorhynchus and Apteronotus albifrons, with reversed sexual dimorphism in their EODs...
October 20, 2017: Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
Wu Yi Zheng, L C Richardson, L Li, R O Day, J I Westbrook, M T Baysari
PURPOSE: Drug-drug interactions (DDIs) are often avoidable and, if undetected, can lead to patient harm. This review aimed to determine the prevalence of potential DDIs (pDDIs), clinically relevant DDIs (DDIs that could lead to measurable patient harm, taking into account the patient's individual clinical profile) and DDIs that resulted in actual patient harm during hospitalisation. METHOD: Four databases were scanned for English papers published from 2000 to 2016...
October 23, 2017: European Journal of Clinical Pharmacology
Ruihuan Li, Jie Xu, Xiangfu Li, Zhen Shi, Paul J Harrison
Phosphorus was the stoichiometrically limiting nutrient in the Pearl River Estuary (PRE). In order to examine how the river discharge regulates phosphorus dynamics in the PRE, the concentrations of dissolved inorganic phosphorus (DIP) and organic phosphorus (DOP), particulate inorganic phosphorus (PIP) and organic phosphorus (POP) in the water column were determined in May 2015 (spring), August 2015 (summer) and January 2016 (winter). Our results showed that all types of phosphorus were significantly lower in spring and summer than in winter...
October 20, 2017: Scientific Reports
Qian Sun, Mirjana Bijelić, Aleksandra B Djurišić, Christian Suchomski, Xiang Liu, Maohai Xie, Alan M C Ng, Hang Kong Li, Kaimin Shih, Sanja Burazer, Željko Skoko, Igor Djerdj, Jasminka Popović
Cation distribution between tetrahedral and octahedral sites within the ZnMn2O4 spinel lattice, along with microstructural features, is affected greatly by the temperature of heat treatment. Inversion parameters can easily be tuned, from 5%-19%, depending on the annealing temperature. The upper limit of inversion is found for T = 400 °C as confirmed by x-ray powder diffraction and Raman spectroscopy. Excellent battery behavior is found for samples annealed at lower temperatures; after 500 cycles the specific capacity for as-prepared ZnMn2O4 is 909 mAh g(-1), while ZnMn2O4 heat-treated at 300 °C is 1179 mAh g(-1), which amounts to 101% of its initial capacity...
October 23, 2017: Nanotechnology
Xinshi Wang, Xin Tian, Yong Yang, Xi Lu, Yun Li, Yuanlin Ma, Yanke Zhang, Fangshuo Zheng, Shanshan Lu, Demei Xu, Xin Xu, Wei Wang, Xuefeng Wang
OBJECTIVES: A protein highly expressed in the CA1-CA3 regions of the hippocampus, plenty of SH3 (POSH) was originally found to be a key regulator of neuronal apoptosis, axon outgrowth, and neuronal migration. However, the role of POSH in epilepsy has not been reported. METHODS: To explore the role of POSH in epilepsy, we investigated the expression of POSH in patients with intractable temporal epilepsy (TLE) and in a kainic acid (KA)-induced mouse model, and then we performed behavioral, electrophysiological and biochemical analyses after the lentivirus (LV)-mediated knockdown or overexpression of POSH in the hippocampus of the KA-induced model...
October 23, 2017: Expert Opinion on Therapeutic Targets
Sushil Patkar
BACKGROUND: Craniovertebral instability following transoral odontoid excision is usually treated by posterior occipital-cervical fixation using occipital plate and cervical lateral mass fixation with screw rod construct. A patient previously operated for basilar invagination had postoperative infection of both the transoral wound and the posterior implant site which needed removal of the posterior implant earlier. CLINICAL PRESENTATION: The patient presented with severe neck pain, myelopathy, and chronic discharging sinus in the posterior lower aspect the previous neck surgery wound...
October 23, 2017: Neurological Research
Federico Mariona, Marianne Burnett, Melody Zoma, Janice Blake, Hanna Khouri
INTRODUCTION: Conjoined twins are an infrequent occurrence in obstetric practice. Live conjoined twins on a late preterm triplet pregnancy is an even rarer event. OBJECTIVE: To emphasize the critical importance of perinatal palliative care and nondirective parental counseling, informed decision making and respect for autonomy following full disclosure of findings, fetal life-limiting diagnosis, treatment alternatives, maternal-fetal potential complications and most likely perinatal outcomes...
October 23, 2017: Journal of Maternal-fetal & Neonatal Medicine
Ying Zhang, Anton Quist, Daniel Enquobahrie
BACKGROUND: Short birth-to-pregnancy intervals have been associated with adverse perinatal outcomes. Racial disparities in short birth-to-pregnancy intervals and adverse perinatal outcomes are also well known. However, little is known about birth-to-pregnancy intervals among African-born black women in the USA and risk factors that contribute to short birth-to-pregnancy intervals in this population. OBJECTIVES: To investigate the risk and associated risk factors of short birth-to-pregnancy intervals among African-born black women in Washington State...
October 23, 2017: Journal of Maternal-fetal & Neonatal Medicine
Annie N Simpson, Janina Wilmskoetter, Ickpyo Hong, Chih-Ying Li, Edward C Jauch, Heather S Bonilha, Kelly Anderson, Jillian Harvey, Kit N Simpson
AIM: Current stroke severity scales cannot be used for archival data. We develop and validate a measure of stroke severity at hospital discharge (Stroke Administrative Severity Index [SASI]) for use in billing data. METHODS: We used the NIH Stroke Scale (NIHSS) as the theoretical framework and identified 285 relevant International Classification of Diseases, 9th Revision diagnosis and procedure codes, grouping them into 23 indicator variables using cluster analysis...
October 23, 2017: Journal of Comparative Effectiveness Research
Wei Wang, Peihao Li, Henry Zheng, Qiao Liu, Fan Lv, Jiandong Wu, Hao Wang, Shaojun Guo
2D electrode materials with layered structures have shown huge potential in the fields of lithium- and sodium-ion batteries. However, their poor conductivity limits the rate performance and cycle stability of batteries. Herein a new colloid chemistry strategy is reported for making 2D ultrathin layered SnSe nanoplates (SnSe NPs) for achieving more efficient alkali-ion batteries. Due to the effect of weak Van der Waals forces, each semiconductive SnSe nanoplate stacks on top of each other, which can facilitate the ion transfer and accommodate volume expansion during the charge and discharge process...
October 23, 2017: Small
James T Frith, Imanol Landa-Medrano, Idoia Ruiz de Larramendi, Teófilo Rojo, John R Owen, Nuria Garcia-Araez
A new route to enhance the performance of Na-O2 cells is demonstrated. Redox mediators (such as ethyl viologen) are shown to facilitate the discharge reaction, producing an increased capacity (due to suppressed electrode passivation), higher discharge potential (due to faster kinetics) and stable cycling.
October 23, 2017: Chemical Communications: Chem Comm
Antonio José Vargas López, Laín Hermes González Quarante, Oscar Lucas Gil de Sagredo Del Corral, Antonio Montalvo Afonso, Carlos Fernández Carballal
We describe an exceptional complication of cervical spine surgery in a 63-year-old male. He suffered the impact of a beam to the top of his head. During evaluation in the emergency room he reported intense neck pain with no other neurological symptoms or findings on physical examination. Spine computed tomography (CT) showed C3 vertebral body fracture that required surgical stabilization. A right side anterior approach to upper cervical spine with C3 corpectomy and placement of iliac bone autograft was performed...
September 2017: Journal of Spine Surgery (Hong Kong)
Joseph L Laratta, Jamal N Shillingford, Joseph M Lombardi, John D Mueller, Hemant Reddy, Comron Saifi, Charla R Fischer, Steven C Ludwig, Lawrence G Lenke, Ronald A Lehman
BACKGROUND: Given the increasing societal focus on health care utilization and value-based care, it is essential to understand the demographic and economic data surrounding percutaneous vertebral augmentation procedures performed in the United States. Double-blinded prospective randomized controlled trials have shown no benefit to the use of vertebroplasty over a sham procedure in the treatment of vertebral fractures. Contrastingly, kyphoplasty may be beneficial when appropriately indicated...
September 2017: Journal of Spine Surgery (Hong Kong)
Owoicho Adogwa, Aladine A Elsamadicy, Emily Lydon, Victoria D Vuong, Joseph Cheng, Isaac O Karikari, Carlos A Bagley
BACKGROUND: Pre-existing cognitive impairment (CI) is emerging as a predictor of poor post-operative outcomes in elderly patients. Little is known about impaired preoperative cognition and outcomes after elective spine surgery in this patient population. The purpose of this study was to assess the prevalence of neuro CI in elderly patients undergoing deformity surgery and its impact on postoperative outcomes. METHODS: Elderly subjects undergoing elective spinal surgery for correction of adult degenerative scoliosis were enrolled in this study...
September 2017: Journal of Spine Surgery (Hong Kong)
Baqar Husaini, Robert Levine, Phillip Lammers, Pam Hull, Meggan Novotny, Majaz Moonis
OBJECTIVE: The role of smoking and depression relative to hospital cost for lung cancer (LC) remains unknown. METHODS: We extracted data on depression, smoking history, demographics, and hospital charges on patients with respiratory cancers (ICD-9 codes 161-163,165) from the 2008 Tennessee Hospital Discharge Data System. The sample (n=6,665) was mostly white (86%) and male (57). Age-adjusted rates were developed per CDC methodology, and hospital costs were compared for LC with vs...
2017: Fam Med Community Health
Ulas M Camsari, Claudia R Libertin
Background  An active intravenous substance use disorder is often the primary cause of infectious diseases in this population of users and creates a barrier to successful parenteral antimicrobial management. The dilemma is compounded by dramatically limited resources in small US towns. Methods This retrospective review from January 2014 through July 2016 aimed to develop a risk stratification approach to aid rural healthcare providers in determining who among patients with addictive disorders could safely be discharged for outpatient antimicrobial therapy with a peripherally inserted central catheter (PICC)...
August 18, 2017: Curēus
Tanya Guenther, Sarah Moxon, Bina Valsangkar, Greta Wetzel, Juan Ruiz, Kate Kerber, Hannah Blencowe, Queen Dube, Shashi N Vani, Donna Vivio, Hema Magge, Socorro De Leon-Mendoza, Janna Patterson, Goldy Mazia
BACKGROUND: As efforts to scale up the delivery of Kangaroo Mother Care (KMC) in facilities are increasing, a standardized approach to measure implementation and progress towards effective coverage is needed. Here, we describe a consensus-based approach to develop a measurement framework and identify a core set of indicators for monitoring facility-based KMC that would be feasible to measure within existing systems. METHODS: The KMC measurement framework and core list of indicators were developed through: 1) scoping exercise to identify potential indicators through literature review and requests from researchers and program implementers; and 2) face-to-face consultations with KMC and measurement experts working at country and global levels to review candidate indicators and finalize selection and definitions...
December 2017: Journal of Global Health
Meshal A Sultan, Darren B Courtney
OBJECTIVES: Recent published evidence suggests that adjunctive trazodone treatment may limit serotonin reuptake inhibitor (SRI) response in depressed adolescents in the context of a controlled trial. This study examined the effects of adjunctive trazodone on depression outcome in adolescents in a naturalistic treatment environment. METHODS: We conducted a cohort study through chart review of a clinical sample. Patients in our sample were 15 to 18 years of age treated with either a selective serotonin reuptake inhibitor or serotonin and norepinephrine reuptake inhibitor...
2017: Journal of the Canadian Academy of Child and Adolescent Psychiatry
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