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Richard Q Loi, Kelly M Leyden, Akshara Balachandra, Vedang Uttarwar, Donald J Hagler, Brianna M Paul, Anders M Dale, Nathan S White, Carrie R McDonald
OBJECTIVE: Diffusion tensor imaging (DTI) has become a popular tool for delineating the location and extent of white matter injury in temporal lobe epilepsy (TLE). However, DTI yields nonspecific measures that are confounded by changes occurring within both the intracellular and extracellular environments. This study investigated whether an advanced diffusion method, restriction spectrum imaging (RSI) could provide a more robust measure of white matter injury in TLE relative to DTI due to RSI's ability to separate intraaxonal diffusion (i...
October 13, 2016: Epilepsia
Rahul Bhat, Maryann Mazer-Amirshahi, Christie Sun, Janelle Vaughns, Maria Dynin, Eshetu Tefera, Daryn Towle, Munish Goyal
OBJECTIVE: There are limited data regarding appropriateness of sedative and paralytic dosing of obese patients undergoing rapid sequence intubation (RSI) in the emergency department. The goal of this study was to compare rates of appropriate succinylcholine and etomidate doses in obese and nonobese patients. METHODS: Retrospective review using a database of endotracheally intubated patients using RSI in an urban, tertiary care academic emergency department, from November 2009 to June 2011...
September 28, 2016: American Journal of Emergency Medicine
Andreas Wolfgang Kyri, Paresh Kumar Majhi, Takahiro Sasamori, Tomohiro Agou, Vitaly Nesterov, Jing-Dong Guo, Shigeru Nagase, Norihiro Tokitoh, Rainer Streubel
Phosphasilenes, P=Si doubly bonded compounds, have received considerable attention due to their unique physical and chemical properties. We report on the synthesis and structure of a chlorophosphasilene coordinated by an N-heterocyclic carbene (NHC), which has the potential of functionalization at the Si-Cl moiety. Treatment of a silylphosphine, ArPH-SiCl₂RSi (Ar = bulky aryl group, RSi = Si(SiMe₃)₃) with two equivalents of Im-Me₄ (1,3,4,5-tetramethylimidazol-2-ylidene) afforded the corresponding NHC-coordinated phosphasilene, ArP=SiClRSi(Im-Me₄) as a stable compound...
September 30, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Lihua Yang, Jinmiao Zha, Zijian Wang
The present study investigated the effects on reproductive and interrenal system by pentachlorophenol (PCP) using in silico and in vivo assays. Molecular docking results indicated interacting potency of PCP with steroid receptors (ERα, ERβ, AR, GR) but not Cytochrome P450 enzymes (CYPs). In the in vivo assay, sexually matured rare minnow (Gobiocypris rarus) was exposed to environmental relevant concentrations of PCP (0, 0.5, 5, 50 μg L(-1)). In male fish, 14-d exposure caused up-regulation of mRNA levels of hepatic erα, erβ, ar, gr, vtg and gonadal erα, vtg, ar, dmrt1, providing evidence for agonistic activities for steroid receptors by PCP...
January 2017: Chemosphere
K A Ahmed, A E Berglund, E A Welsh, A O Naghavi, B A Perez, T J Dilling, S A Eschrich, J F Torres-Roca
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
K A Ahmed, T Strom, J G Scott, E A Welsh, H L McLeod, L B Harrison, S A Eschrich, J F Torres-Roca
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
David Nieder, Volker Huch, Cem B Yildiz, David Scheschkewitz
An isolable NHC-coordinated disilenyl germylene R2Si═SiR-GePh·NHC(iPr2)(Me2) (5b: R = 2,4,6-triisopropylphenyl, NHC(iPr2)(Me2) = 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene) is obtained from the reaction of the α-chloro silyl functionalized heavier vinylidene analogue R2(Cl)Si-RSi═Ge·NHC(iPr2)(Me2) with phenyllithium. The disilenyl germylene 5b isomerizes at 40 °C to the NHC-adduct of the corresponding heavier cyclopropylidene analogue 6b. Both 5b and 6b display near perfect regiodiscrimination in their reactions with phenylacetylene and xylyl isocyanide, affording in the case of each reagent two different regioisomers of NHC-coordinated cyclic germylenes...
October 14, 2016: Journal of the American Chemical Society
H L Han, J H Zhao, Y L Zhang, M Wang, H F Wang, J N Cheng, Y Feng, K Q Luo, Q P Lyu
Objective: To summarize the application and significance of Dx-pH monitoring system in laryngopharyngeal reflux disease. Methods: Fifty-four patients who had symptoms of laryngopharyngeal reflux disease in our department from February to December in 2015 were retrospectively analyzed in this study. All patients were evaluated with reflux symptoms index(RSI), flexible laryngoscope and reflux finding score(RFS), and larygopharygeal Dx-pH monitoring. Results: Among all 54 patients, there were 26 patients whose Ryan score were positive(48...
September 7, 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
J S Wang, J R Li
Objective: To evaluate the consistency between 24-hour pH monitoring, reflux symptom index(RSI) and reflux finding score(RFS) when using pH<4 or pH<5 as threshold for 24-hour pH monitoring in the diagnosis of laryngopharyngeal reflux. Methods: Patients who presented with suspicious laryngopharyngeal reflux between February 2014 and December 2015 were included in this study. pH<4 and pH<5 reflux episodes, RSI and RFS were collected. The consistency between 24-hour pH monitoring and scale results were analyzed when pH<4 or pH<5 as threshold respectively...
September 7, 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Yoshio Inoue, Martine Guérif, Frédéric Baret, Andrew Skidmore, Anatoly Gitelson, Martin Schlerf, Roshanak Darvishzadeh, Albert Olioso
Canopy chlorophyll content (CCC) is an essential ecophysiological variable for photosynthetic functioning. Remote sensing of CCC is vital for a wide range of ecological and agricultural applications. The objectives of this study were to explore simple and robust algorithms for spectral assessment of CCC. Hyperspectral datasets for six vegetation types (rice, wheat, corn, soybean, sugar beet and natural grass) acquired in four locations (Japan, France, Italy and USA) were analysed. To explore the best predictive model, spectral index approaches using the entire wavebands and multivariable regression approaches were employed...
September 21, 2016: Plant, Cell & Environment
Jessica M Pisegna, Sky Yang, Audrey Purcell, Alix Rubio
OBJECTIVES: Gastroesophageal reflux disease is a chronic disorder often accompanied by laryngopharyngeal reflux. Speech-language pathologists are tasked with treating these patients with voice, dysphagia, and/or reflux therapy. This study investigated patient-reported reasons for reduced compliance with recommended reflux treatment and the top symptoms in patients with reflux, dysphagia, and voice symptoms. STUDY DESIGN: This study used a cross-sectional qualitative and quantitative mixed-methods design to identify and describe patients' reflux symptoms and reflux medication routines...
September 16, 2016: Journal of Voice: Official Journal of the Voice Foundation
Leressè Pillay, Timothy Hardcastle
INTRODUCTION: Establishing a definitive airway in order to ensure adequate ventilation and oxygenation is an important aspect of resuscitation of the polytrauma patient . AIM: To review the relevant literature that compares the different drugs used for rapid sequence intubation (RSI) of trauma patients, specifically reviewing: premedication, induction agents and neuromuscular blocking agents across the prehospital, emergency department and operating room setting, and to present the best practices based on the reviewed evidence...
September 19, 2016: World Journal of Surgery
Arun Garg, J Steven Moore, Jay M Kapellusch
The Revised Strain Index (RSI) is a distal upper extremity (DUE) physical exposure assessment model based on: intensity of exertion, frequency of exertion, duration per exertion, hand/wrist posture and duration of task per day. The RSI improves upon the 1995 Strain Index (SI) by using continuous rather than categorical multipliers, and replacing duty cycle with duration per exertion. In a simulation of 13,944 tasks, the RSI and 1995 SI showed good agreement in risk predictions for 1995 SI scores ≤3 (safe) and >13...
October 14, 2016: Ergonomics
Kris Beattie, Brian P Carson, Mark Lyons, Ian C Kenny
Maximum- and reactive-strength qualities both have important roles in athletic movements and sporting performance. Very little research has investigated the relationship between maximum-strength and reactive-strength. The aim of this study was to investigate the relationship between maximum-strength (isometric mid-thigh pull peak force; IMTP PF) and reactive-strength (drop-jump reactive-strength index; DJ-RSI) variables at 0.3 m, 0.4 m, 0.5 m and 0.6 m box heights. A secondary aim investigated the between- and within-group differences in reactive-strength characteristics between relatively 'strong' and 'weak' athletes...
September 6, 2016: International Journal of Sports Physiology and Performance
Richard C Pardo
No abstract text is available yet for this article.
August 2016: Review of Scientific Instruments
Zixian Yang, Therma Wai Chun Cheung
BACKGROUND: Risk factors contributing to upper limb repetitive stress injuries (RSIs) have been well-documented in literature, but there has been no such data in Singapore. OBJECTIVE: To investigate potential contributory factors to upper limb RSIsMETHODS: We performed a retrospective cohort study of clients who were referred to outpatient upper limb rehabilitation in 2012. Demographic information was retrieved from an electronic documentation system. Descriptive analyses were performed using Statistical Package for Social Sciences (SPSS) Version 17...
August 12, 2016: Work: a Journal of Prevention, Assessment, and Rehabilitation
Turid Torheim, Aurora R Groendahl, Erlend K F Andersen, Heidi Lyng, Eirik Malinen, Knut Kvaal, Cecilia M Futsaether
BACKGROUND: Solid tumors are known to be spatially heterogeneous. Detection of treatment-resistant tumor regions can improve clinical outcome, by enabling implementation of strategies targeting such regions. In this study, K-means clustering was used to group voxels in dynamic contrast enhanced magnetic resonance images (DCE-MRI) of cervical cancers. The aim was to identify clusters reflecting treatment resistance that could be used for targeted radiotherapy with a dose-painting approach...
November 2016: Acta Oncologica
Evan C Cumpston, Joel H Blumin, Jonathan M Bock
OBJECTIVES: Minimal data exist to define the use of contemporary dual pH with multichannel intraluminal impedance (MII) probes integrating both pharyngeal acid and impedance sensors to evaluate laryngopharyngeal reflux (LPR) symptoms in a laryngology clinic population. This study was performed to review a series of patients tested with dual pH-MII for suspected LPR symptoms and to analyze pH-MII data findings for this patient cohort. STUDY DESIGN: Case series with planned data collection...
August 23, 2016: Otolaryngology—Head and Neck Surgery
Dan Zhu, Yudong Mei, Yujian Shi, Dekun Hu, Yong Ren, Quan Gu, Wenbiao Shen, Xin Chen, Lingxi Xu, Liqin Huang
β-cyclodextrin-hemin complex (β-CDH) was shown to induce lateral root (LR) formation in tomato. However, the molecular mechanism is still elusive. In this report, the role of reduced glutathione (GSH) in the induction of lateral root triggered by β-CDH was investigated. Similar to the responses of β-CDH, exogenously applied with 0.1 mΜ GSH not only increased endogenous GSH content determined by spectrophotography and the monochlorobimane (MCB)-dependent fluorescent analysis, but also induced, thereafter, LR formation...
October 1, 2016: Journal of Plant Physiology
Gulcan Harput, Damla Tok, Burak Ulusoy, Leyla Eraslan, Taha Ibrahim Yildiz, Elif Turgut, Serdar Demirci, Irem Duzgun, Volga Bayrakci Tunay, Gul Baltaci, Nevin Ergun
PURPOSE: To translate and culturally adapt the anterior cruciate ligament-return to sport after injury (ACL-RSI) scale into Turkish (ACL-RSI-Tr) and examine and evaluate the psychometric properties of the Turkish version in individuals who have undergone anterior cruciate ligament (ACL) reconstruction. METHODS: The ACL-RSI was forward- and back-translated, culturally adapted and validated on ninety-three Turkish individuals who had undergone ACL reconstruction (5 females, 88 males; age 28...
August 18, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
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