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https://www.readbyqxmd.com/read/28647423/sterilizing-service-unit-packing-area-to-glove-or-regular-hand-hygiene-that-is-the-question
#1
Dayane de Melo Costa, Lillian Kelly de Oliveira Lopes, Anaclara Ferreira Veiga Tipple, Roel Beltran Castillo, Honghua Hu, Anand Kumar Deva, Karen Vickery
BACKGROUND: During functionality testing and packaging of reusable surgical instruments (RSI) for sterilisation, instruments are frequently touched. Considering the lack of standards relating to hand hygiene frequency and use of gloves in the sterilising service unit packing area, we aimed to determine the effect of hand hygiene and glove use on maintenance of RSI cleanliness. METHODS: Following manual and automated cleaning, Halsted-mosquito forceps were assessed for adenosine triphosphate (ATP), protein and microbial contamination after handling with gloved and ungloved but washed hands utilising an ATP surface swab test, bicinchoninic acid assay, and standard culture plate/broth, respectively...
June 21, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28622071/survival-in-out-of-hospital-rapid-sequence-intubation-of-non-traumatic-brain-pathologies
#2
Pieter Francsois Fouche, Paul Andrew Jennings, Karen Smith, Malcolm Boyle, Gabriel Blecher, Jonathan Knott, Mani Raji, Pamela Rosengarten, Michael Roberto Augello, Stephen Bernard
INTRODUCTION: Rapid sequence intubation (RSI) is not only used in traumatic brain injuries in the out-of-hospital setting, but also for non-traumatic brain pathologies (NTBP) such as brain tumors, meningitis, encephalitis, hypoxic/anoxic brain injury, stroke, arteriovenous malformations, tumors, aneurysms, brain hemorrhage, as well as brain injury due to diabetes, seizures and toxicity, metabolic conditions, and alcohol and drug overdose. Previous research suggests that RSI is common in non-traumatic coma, but with an unknown prevalence of NTBP in those that receive RSI...
June 16, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28620964/does-gene-expression-in-laryngeal-sub-sites-differ-between-patients-with-laryngopharyngeal-reflux-and-controls
#3
John M Wood, Damian J Hussey, Charmaine M Woods, David Astill, David I Watson, Bernard Lee, A Simon Carney
OBJECTIVE: to identify laryngeal mRNA gene changes in patients with laryngopharyngeal reflux (LPR). METHOD: Laryngeal biopsies from non-smoking LPR patients (n=10; Reflux Symptom Index (RSI) >12 and a Reflux Finding Score (RFS) >6) and controls (n=9; RSI <12 and RFS <6) were collected from 4 sub-sites (true vocal cord, false vocal cord, medial arytenoid, posterior commissure) of the larynx. qRT-PCR analyses were conducted on 20 reflux and inflammation related genes, including interleukin 6 and 8, cytokeratin 8 and 14, mucin genes MUC 1, 2, 3B, 4, 5B, 6 & 7, and carbonic anhydrase III...
June 16, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28606786/the-utility-of-the-reflux-symptom-index-for-diagnosis-of-laryngopharyngeal-reflux-in-an-allergy-patient-population
#4
David L Brauer, Kevin Y Tse, Jane C Lin, Michael X Schatz, Ronald A Simon
BACKGROUND: Laryngopharyngeal reflux (LPR) is associated with asthma, vocal cord dysfunction, cough, postnasal drainage, and throat irritation. The Reflux Symptom Index (RSI) is a clinical tool to predict the presence of LPR, but a threshold RSI score has never been validated for the diagnosis of LPR in an allergic patient population. OBJECTIVE: To identify the optimal threshold RSI score predictive of LPR in an allergy clinic population. METHODS: The 9-question RSI questionnaire was administered to 84 patients in the Kaiser Permanente San Diego Allergy Department...
June 9, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28598440/an-autonomous-organic-reaction-search-engine-for-chemical-reactivity
#5
Vincenza Dragone, Victor Sans, Alon B Henson, Jaroslaw M Granda, Leroy Cronin
The exploration of chemical space for new reactivity, reactions and molecules is limited by the need for separate work-up-separation steps searching for molecules rather than reactivity. Herein we present a system that can autonomously evaluate chemical reactivity within a network of 64 possible reaction combinations and aims for new reactivity, rather than a predefined set of targets. The robotic system combines chemical handling, in-line spectroscopy and real-time feedback and analysis with an algorithm that is able to distinguish and select the most reactive pathways, generating a reaction selection index (RSI) without need for separate work-up or purification steps...
June 9, 2017: Nature Communications
https://www.readbyqxmd.com/read/28596691/nissen-fundoplication-vs-proton-pump-inhibitors-for-laryngopharyngeal-reflux-based-on-ph-monitoring-and-symptom-scale
#6
Chao Zhang, Zhi-Wei Hu, Chao Yan, Qiong Wu, Ji-Min Wu, Xing Du, Dian-Gang Liu, Tao Luo, Fei Li, Zhong-Gao Wang
AIM: To compare the outcomes between laparoscopic Nissen fundoplication (LNF) and proton pump inhibitors (PPIs) therapy in patients with laryngopharyngeal reflux (LPR) and type I hiatal hernia diagnosed by oropharyngeal pH-monitoring and symptom-scale assessment. METHODS: From February 2014 to January 2015, 70 patients who were diagnosed with LPR and type I hiatal hernia and referred for symptomatic assessment, oropharyngeal pH-monitoring, manometry, and gastrointestinal endoscopy were enrolled in this study...
May 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28593484/reflux-sleeve-dilation-and-barrett-s-esophagus-after-laparoscopic-sleeve-gastrectomy-long-term-follow-up
#7
Daniel Moritz Felsenreich, Ronald Kefurt, Martin Schermann, Philipp Beckerhinn, Ivan Kristo, Michael Krebs, Gerhard Prager, Felix B Langer
BACKGROUND: Laparoscopic sleeve gastrectomy (SG) has become the most frequently performed bariatric procedure worldwide. De novo reflux might impact patients' quality of life, requiring lifelong proton pump inhibitor medication. It also increases the risk of esophagitis and formation of Barrett's metaplasia. Besides weight regain, gastroesophageal reflux disease (GERD) is the most common reason for conversion to Roux-en-Y gastric bypass. METHODS: We performed 24-h pH metries, manometries, gastroscopies, and questionnaires focusing on reflux (GIQLI, RSI) in SG patients with a follow-up of more than 10 years who did not suffer from symptomatic reflux or hiatal hernia preoperatively...
June 8, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28566815/training-induced-changes-in-physical-performance-can-be-achieved-without-body-mass-reduction-after-eight-week-of-strength-and-injury-prevention-oriented-programme-in-volleyball-female-players
#8
M Lehnert, M Sigmund, P Lipinska, R Vařeková, M Hroch, Z Xaverová, P Stastny, P Háp, P Zmijewski
The purpose of the study was to analyse the changes in muscle strength, power, and somatic parameters in elite volleyball players after a specific pre-season training programme aimed at improving jumping and strength performance and injury prevention. Twelve junior female volleyball players participated in an 8-week training programme. Anthropometric characteristics, isokinetic peak torque (PT) single-joint knee flexion (H) and extension (Q) at 60º/s and 180º/s, counter movement jump (CMJ), squat jump (SJ), and reactive strength index (RSI) were measured before and after intervention...
June 2017: Biology of Sport
https://www.readbyqxmd.com/read/28562558/clinicopathological-parameters-associated-with-histological-background-and-recurrence-after-surgical-intervention-of-vocal-cord-leukoplakia
#9
Weixin Cui, Wen Xu, Qingwen Yang, Rong Hu
Histological examination of biopsy shows usefulness in the diagnosis of vocal cord leukoplakia; however, in considerable amount of cases, the examination cannot provide definitive diagnosis of malignancy from benign conditions such as hyperplasia and dysplasia. The present work therefore was aimed to identify clinicopathological factors and molecular markers predictive of recurrence and malignant transformation of vocal cord leukoplakia.Clinical data of 555 cases of vocal cord leukoplakia enrolled from July 1999 to June 2014 were analyzed...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28522132/salivary-pepsin-test-useful-and-simple-tool-for-the-laryngopharyngeal-reflux-diagnosis
#10
Luz Barona-Lleó, Claudia Duval, Rafael Barona-de Guzmán
INTRODUCTION AND OBJECTIVES: Laryngopharyngeal Reflux (LPR) is a disease characterized by the presence of symptoms, signs and tissue damage caused by retrograde flow of gastric contents to the upper aerodigestive tract. It represents up to 10% of otolaryngology consultations. The aim of the study is to describe the findings obtained by applying the salivary pepsin test (PEP-test) in a sample of patients with the clinical suspicion of LPR. MATERIAL AND METHODS: Our descriptive clinical study included 142 subjects with symptoms suggestive of LPR and a score above 13 on the RSI scale...
May 15, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/28449553/changes-in-the-reflux-symptom-index-after-multilevel-surgery-for-obstructive-sleep-apnea
#11
Su Jin Kim, Hyo Yeol Kim, Jong In Jeong, Sang Duk Hong, Seung-Kyu Chung, Hun-Jong Dhong
Objectives: This study evaluated whether the symptoms of laryngopharyngeal reflux (LPR) change after multilevel surgery for obstructive sleep apnea (OSA). Methods: Patients who underwent multilevel surgery for OSA between April 2009 and September 2014 were enrolled in this study. All patients underwent preoperative polysomnography prior to surgery and were asked to complete the reflux symptom index (RSI) questionnaire before and after surgery. Results: Of 73 enrolled patients, 24 (33%) reported an RSI score >13 and were thus classified as having reflux...
April 28, 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28438369/independent-prognostic-importance-of-respiratory-instability-and-sympathetic-nerve-activity-in-patients-with-chronic-heart-failure
#12
Hidetsugu Asanoi, Daisuke Harada, Yoshitaka Oda, Hiroshi Ueno, Junya Takagawa, Hisanari Ishise, Yukiko Goso, Shuji Joho, Hiroshi Inoue
BACKGROUND: Respiratory instability in chronic heart failure (CHF) is characterized by irregularly rapid respiration or non-periodic breathing rather than by Cheyne-Stokes respiration. We developed a new quantitative measure of respiratory instability (RSI) and examined its independent prognostic impact upon CHF. METHODS: In 87 patients with stable CHF, respiratory flow and muscle sympathetic nerve activity (MSNA) were simultaneously recorded. RSI was calculated from the frequency distribution of respiratory spectral components and very low frequency components...
April 21, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28422586/the-reactive-strength-index-reflects-vertical-stiffness-during-drop-jumps
#13
Kristof Kipp, Michael T Kiely, Matthew D Giordanelli, Philip J Malloy, Christopher F Geiser
The reactive strength index (RSI) is often used to quantify drop jump (DJ) performance; however, not much is known about the biomechanical determinants of the RSI. The purpose of this study was to investigate the correlations between the RSI and several biomechanical variables calculated from DJ performed with different initial drop heights. Twelve, male NCAA DI basketball players performed DJ from drop heights of 30, 45, and 60 cm. Force plates were used to calculate DJ performance parameters (i.e., DJ height, contact time, and RSI) and DJ biomechanical variables (i...
April 19, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28412967/factors-associated-with-lingual-tonsil-hypertrophy-in-canadian-adults
#14
Matthew S Harris, Brian W Rotenberg, Kathryn Roth, Leigh J Sowerby
BACKGROUND: Hypertrophy of the lingual tonsil tissue in the adult patient is thought to contribute to the pathophysiology of obstructive sleep apnea. The underlying etiology of lingual tonsil hypertrophy (LTH) in the adult patient is unclear and likely multifactorial. Previous studies have suggested that the lingual tonsils may undergo compensatory hyperplasia post-tonsillectomy in children, although it is unknown if this occurs or persists into adulthood. The purpose of this study was to determine what factors are associated with LTH in a population of Canadian adults...
April 17, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28412161/the-effect-of-the-apneic-period-on-the-respiratory-physiology-of-patients-undergoing-intubation-in-the-emergency-department
#15
Jason R West, Anthony Scoccimarro, Cody Kramer, Nicholas D Caputo
OBJECTIVES: We sought to examine the physiological impact the apneic period has on the respiratory physiology of patients undergoing intubation in the emergency department and whether DAO, the delivery of 15L oxygen by nasal cannula during apnea, can affect the development of respiratory acidosis. METHODS: This was a prospective observational cohort study conducted at an urban academic level 1 trauma center. A convenience sample of 100 patients was taken. Timed data collection forms were completed during the periintubation period...
April 2, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28407872/further-investigation-of-distinct-components-of-stroop-interference-and-of-their-reduction-by-short-response-stimulus-intervals
#16
Maria Augustinova, Laetitia Silvert, Nicolas Spatola, Ludovic Ferrand
The aim of this paper is to extend the so-called semantic Stroop paradigm (Neely & Kahan, 2001) - which already successfully distinguishes between the contribution of the semantic vs. response conflict to Stroop interference - so that it can take account of and capture the separate contribution of task conflict. In line with this idea, the Stroop interference observed using the aforementioned paradigm with both short and long RSIs (500 vs. 2000ms) did indeed reflect the specific contribution of the task, semantic and response conflicts...
April 10, 2017: Acta Psychologica
https://www.readbyqxmd.com/read/28404758/regional-radiation-therapy-impacts-outcome-for-node-positive-cutaneous-melanoma
#17
Tobin Strom, Javier F Torres-Roca, Akash Parekh, Arash O Naghavi, Jimmy J Caudell, Daniel E Oliver, Jane L Messina, Nikhil I Khushalani, Jonathan S Zager, Amod Sarnaik, James J Mulé, Andy M Trotti, Steven A Eschrich, Vernon K Sondak, Louis B Harrison
Background: Regional radiation therapy (RT) has been shown to reduce the risk of regional recurrence with node-positive cutaneous melanoma. However, risk factors for regional recurrence, especially in the era of sentinel lymph node biopsy (SLNB), are less clear. Our goals were to identify risk factors associated with regional recurrence and to determine whether a radiosensitivity index (RSI) gene expression signature (GES) could identify patients who experience a survival benefit with regional RT. Methods: A single-institution, Institutional Review Board-approved study was performed including 410 patients treated with either SLNB with or without completion lymph node dissection (LND; n=270) or therapeutic LND (n=91)...
April 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28398072/the-reactive-species-interactome-evolutionary-emergence-biological-significance-and-opportunities-for-redox-metabolomics-and-personalized-medicine
#18
Miriam M Cortese-Krott, Anne Koning, Gunter G C Kuhnle, Peter Nagy, Christopher L Bianco, Andreas Pasch, David A Wink, Jon M Fukuto, Alan A Jackson, Harry van Goor, Kenneth R Olson, Martin Feelisch
SIGNIFICANCE: Oxidative stress is thought to account for aberrant redox homeostasis and contribute to aging and disease. However, more often than not, administration of antioxidants is ineffective, suggesting that our current understanding of the underlying regulatory processes is incomplete. Recent Advances: Similar to reactive oxygen species and reactive nitrogen species, reactive sulfur species are now emerging as important signaling molecules, targeting regulatory cysteine redox switches in proteins, affecting gene regulation, ion transport, intermediary metabolism, and mitochondrial function...
June 6, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/28368956/the-effect-of-varying-plyometric-volume-on-stretch-shortening-cycle-capability-in-collegiate-male-rugby-players
#19
Mark Jeffreys, Mark De Ste Croix, Rhodri S Lloyd, Jon L Oliver, Jonathan Hughes
The purpose of this study was to identify the effectiveness of low and high volume plyometric loads on developing stretch shortening cycle capability in collegiate rugby players. A between- group repeated measures design was used. Thirty six subjects (age 20.3 ±1.6 yrs, mass 91.63 ±10.36kg, stature 182.03 ±5.24cm) were randomly assigned to one of three groups, a control group (CG), a low volume plyometric group (LPG) or a high volume plyometric group (HPG). Data were collected from a force plate, and measures of reactive strength index (RSI) and leg stiffness were calculated from jump height, contact time and flight time...
March 25, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28352868/flexible-organofunctional-aerogels
#20
C R Ehgartner, S Grandl, A Feinle, N Hüsing
Flexible inorganic-organic silica aerogels based on methyltrimethoxysilane (MTMS, CH3Si(OCH3)3) can overcome the drawbacks of conventional silica aerogels by introducing high mechanical strength, elastic recovery and hydrophobicity to monolithic materials. In this work, MTMS is co-condensed with organofunctional alkoxysilanes RSi(OMe)3 (R = vinyl, chloropropyl, mercaptopropyl, methacryloxypropyl, etc.) yielding aerogels that are not only flexible but also contain reactive functional groups. Sol-gel parameters, such as the MTMS/RSi(OMe)3 ratio, have been systematically investigated in terms of gelation behavior, complete/incomplete incorporation of the functional organic groups (confirmed by FTIR-ATR and Raman spectroscopy) and flexibility of the resulting gel...
March 29, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
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