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https://www.readbyqxmd.com/read/28930884/rate-of-macular-ganglion-cell-inner-plexiform-layer-thinning-in-glaucomatous-eyes-with-vascular-endothelial-growth-factor-inhibition
#1
Won June Lee, Young Kook Kim, Yong Woo Kim, Jin Wook Jeoung, Seok Hwan Kim, Jang Won Heo, Hyeong Gon Yu, Ki Ho Park
PURPOSE: To evaluate the rate of progressive macular ganglion cell-inner plexiform layer (GCIPL) thinning in patients with open-angle glaucoma (OAG) who had been treated with intravitreal anti-vascular endothelial growth factor (VEGF) injection for wet age-related macular degeneration (AMD). METHODS: This study was a retrospective modified case control study with fellow-eye comparison. We enrolled bilateral OAG patients who had been treated with repeated anti-VEGF injections for unilateral wet AMD and followed-up on for a minimum of 24 months by Cirrus high-definition optical coherence tomography (HD-OCT)...
September 19, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28917411/accelerated-15%C3%A2-mw-pulsed-light-crosslinking-to-treat-progressive-keratoconus-two-year-clinical-results
#2
Cosimo Mazzotta, Stefano Baiocchi, Simone Alex Bagaglia, Mario Fruschelli, Alessandro Meduri, Miguel Rechichi
PURPOSE: To assess the clinical and microstructural results of accelerated 15 mW pulsed-light corneal crosslinking (CXL) to treat progressive keratoconus. SETTING: Siena Crosslinking Center, Siena, Italy. DESIGN: Prospective case series. METHODS: After epithelium removal (with Epi-Clear) and 10 minutes stromal soaking with riboflavin 0.1% hydroxypropyl methylcellulose solution, all eyes had 15 mW/cm(2) pulsed-light epithelium-off accelerated CXL for 6 minutes of ultraviolet-A (UVA) irradiation (1 second on/1 second off), maintaining a total UVA exposure of 12 minutes at a fluence of 5...
August 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28917092/progressive-halo-vest-traction-preceding-posterior-occipitocervical-instrumented-fusion-for-irreducible-atlantoaxial-dislocation-and-basilar-invagination
#3
Peng Li, Deming Bao, Huijuan Cheng, Fanshuai Meng, Junwei Li
OBJECTIVES: Surgical treatment of irreducible atlantoaxial dislocation (IAAD) with basilar invagination (BI) is associated with high rates of severe complications, including mortality. This retrospective study investigated the safety and efficacy of progressive halo-vest traction for IAAD with BI prior to posterior occipitocervical instrumented fusion. PATIENTS AND METHODS: Between 2009 and 2013, 39 patients with IAAD with BI underwent preoperative reduction by progressive halo-vest traction for 20...
September 5, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28915318/applications-of-high-resolution-magic-angle-spinning-mrs-in-biomedical-studies-ii-human-diseases
#4
REVIEW
Christopher Dietz, Felix Ehret, Francesco Palmas, Lindsey A Vandergrift, Yanni Jiang, Vanessa Schmitt, Vera Dufner, Piet Habbel, Johannes Nowak, Leo L Cheng
High-resolution magic angle spinning (HRMAS) MRS is a powerful method for gaining insight into the physiological and pathological processes of cellular metabolism. Given its ability to obtain high-resolution spectra of non-liquid biological samples, while preserving tissue architecture for subsequent histopathological analysis, the technique has become invaluable for biochemical and biomedical studies. Using HRMAS MRS, alterations in measured metabolites, metabolic ratios, and metabolomic profiles present the possibility to improve identification and prognostication of various diseases and decipher the metabolomic impact of drug therapies...
September 15, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28913126/angular-pregnancy
#5
İbrahim Alanbay, Mustafa Öztürk, Kazım Emre Karaşahin, Müfit Cemal Yenen
Angular pregnancy is a rare condition in which the embryo is implanted in the lateral angle of the uterine cavity, medial to the uterotubal junction and round ligament, and causes life-threatening obstetric complications. It is important to differentiate this condition from interstitial and cornual pregnancy because they all result in emergency conditions. Although angular pregnancy can progress to term pregnancy, it may be associated with major obstetric complications such as uterine rupture, placental retention, postpartum hemorrhage, or may need further surgery and hysterectomy...
December 2016: Turk J Obstet Gynecol
https://www.readbyqxmd.com/read/28905003/an-immediate-effect-of-pnf-specific-mobilization-on-the-angle-of-trunk-rotation-and-the-trunk-pelvis-hip-angle-range-of-motion-in-adolescent-girls-with-double-idiopathic-scoliosis-a-pilot-study
#6
A Stępień, K Fabian, K Graff, M Podgurniak, A Wit
BACKGROUND: Impairment of spine rotation is a key concept in several theories explaining the pathogenesis and progression of scoliosis. In previous studies, a more limited range of motion in scoliotic girls compared to their non-scoliotic peers was noted. The Trunk-Pelvis-Hip Angle measurement is a test used to assess the range of motion in the trunk-pelvis-hip complex in the transverse plane. The aim of this study was to assess an immediate effect of Proprioceptive Neuromuscular Facilitation specific mobilization (mPNF) on the angle of trunk rotation and Trunk-Pelvis-Hip Angle range of motion in adolescent girls with double scoliosis...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/28904636/the-orthopaedic-management-of-lower-limb-deformity-in-hypophosphataemic-rickets
#7
A Horn, J Wright, D Bockenhauer, W Van't Hoff, D M Eastwood
BACKGROUND: Many patients with X-linked hypophosphataemic rickets (X-LHPR) demonstrate significant lower limb deformity despite optimal medical management. This study evaluates the use of guided growth by means of hemi-epiphysiodesis to address coronal plane deformity in the skeletally immature child. METHODS: Since 2005, 24 patients with X-LHPR have been referred to our orthopaedic unit for evaluation. All patients had standardised long leg radiographs that were analysed sequentially before and after surgery if any was performed...
August 1, 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28902104/a-replication-study-for-the-association-of-rs11190870-with-curve-severity-in-adolescent-idiopathic-scoliosis-in-japanese
#8
Yohei Takahashi, Ikuyo Kou, Yoji Ogura, Atsushi Miyake, Kazuki Takeda, Masahiro Nakajima, Shohei Minami, Noriaki Kawakami, Koki Uno, Manabu Ito, Ikuho Yonezawa, Takashi Kaito, Haruhisa Yanagida, Kei Watanabe, Hiroshi Taneichi, Katsumi Harimaya, Yuki Taniguchi, Toshiaki Kotani, Taichi Tsuji, Teppei Suzuki, Hideki Sudo, Nobuyuki Fujita, Mitsuru Yagi, Kazuhiro Chiba, Katsuki Kono, Tsuyoshi Sakuma, Tsutomu Akazawa, Kotaro Nishida, Kenichiro Kakutani, Hideki Shigematsu, Takahiro Iida, Satoshi Demura, Naobumi Hosogane, Eijiro Okada, Masaya Nakamura, Morio Matsumoto, Kota Watanabe, Shiro Ikegawa
STUDY DESIGN: Case-only study. OBJECTIVE: The aim of this study was to confirm the association of rs11190870 with AIS severity in Japanese patients with AIS. SUMMARY OF BACKGROUND DATA: Although the association of rs11190870 with AIS susceptibility is replicated in multiple ethnics, the association of rs11190870 with curve severity is controversial. Since the previous studies are of small, we performed a replication study using far larger number of patients than previous studies...
September 8, 2017: Spine
https://www.readbyqxmd.com/read/28902001/guided-growth-of-the-proximal-femur-for-the-management-of-hip-dysplasia-in-children-with-cerebral-palsy
#9
Nicola Portinaro, Marco Turati, Matteo Cometto, Marco Bigoni, Jon R Davids, Artemisia Panou
BACKGROUND: Progressive hip displacement is one of the most common and debilitating deformities seen in children with cerebral palsy (CP). The aim of this study was to evaluate the results of temporary medial hemiepiphysiodesis of the proximal femur (TMH-PF) using a transphyseal screw to control hip migration during growth in children with CP. METHODS: This was a retrospective study of children with CP and hip dysplasia, age 4 to 11 years and GMFCS levels III-V...
September 8, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28900607/de-novo-intraocular-amyloid-deposition-after-hepatic-transplantation-in-familial-amyloidotic-polyneuropathy
#10
Ivo Filipe Gama, Leonor Duarte Almeida
The familiar amyloid polyneuropathy (FAP) is a rare autosomal-dominant systemic amyloidosis. Amyloid deposition occurs more frequently and extensively in the vitq. The increase in intraocular pressure (IOP) is a result of deposition of transthyretin (TTR) in trabecular meshwork. Rarely, the amyloid deposition in anterior segment can be more exuberant than in posterior segment. A 42 years old man, with FAP (Val30Met mutation), liver transplantation in 1997. He was asymptomatic, without any significant ocular abnormality until 2011...
August 24, 2017: World Journal of Transplantation
https://www.readbyqxmd.com/read/28889406/intrapartum-transperineal-ultrasound-used-to-predict-cases-of-complicated-operative-vacuum-and-forceps-deliveries-in-nulliparous-women
#11
José Antonio Sainz, José Antonio García-Mejido, Adriana Aquise, María José Bonomi, Carlota Borrero, Paloma De la Fuente, Ana Fernández-Palacín
INTRODUCTION: The objective of this study was to investigate the predictive value of intrapartum transperineal ultrasound in the identification of complicated operative(vacuum or forceps) deliveries in nulliparous women. MATERIAL AND METHODS: Prospective observational study of nulliparous women with an indication for operative-delivery who underwent intrapartum transperineal ultrasound before fetal extraction. Managing obstetricians were blinded to the ultrasound data...
September 10, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28886580/a-plasma-metabonomic-analysis-on-potential-biomarker-in-pyrexia-induced-by-three-methods-using-ultra-high-performance-liquid-chromatography-coupled-with-fourier-transform-ion-cyclotron-resonance-mass-spectrometry
#12
Ting Liu, Songhe Li, Xiumin Tian, Zhaoqin Li, Yue Cui, Fei Han, Yunli Zhao, Zhiguo Yu
Pyrexia usually is a systemic pathological process that can lead to metabolic disorders. Metabonomics as a powerful tool not only can reveal the pathological mechanisms, but also can give insight into the progression of pyrexia from another angle. Thus, an ultra high performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry (UHPLC-FT-ICR-MS) metabonomic approach was employed for the first time to investigate the plasma biochemical characteristics of pyrexia induced by three methods and to reveal subtle metabolic changes under the condition of pyrexia so as to explore its mechanism...
August 24, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28885636/further-expanding-versatility-of-surface-enhanced-raman-spectroscopy-from-non-traditional-sers-active-to-sers-inactive-substrates-and-single-shell-isolated-nanoparticle
#13
Song-Yuan Ding, En-Ming You, Jun Yi, Jian-Feng Li, Zhong-Qun Tian
After surface-enhanced Raman spectroscopy (SERS) was initiated over four decades ago, its practical application seems to be far behind the fundamental research that has made tremendous progress. SERS as a highly sensitive technique has not been widely adopted by the materials science and surface science communities or in the market of analytical instruments. In this discussion, we first classify the previous approaches along this direction over the past four decades and divide them into three strategies. Based on our recent theoretical and experimental approaches, we discuss in more detail the third strategy related to shell-isolated nanostructures...
September 8, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28885088/progression-of-trunk-imbalance-in-adolescent-idiopathic-scoliosis-with-a-thoracolumbar-lumbar-curve-is-it-predictable-at-the-initial-visit
#14
Chang Ju Hwang, Choon Sung Lee, Dong-Ho Lee, Jae Hwan Cho
OBJECTIVE Progression of trunk imbalance is an important finding during follow-up of patients with adolescent idiopathic scoliosis (AIS). Nevertheless, no factors that predict progression of trunk imbalance have been identified. The purpose of this study was to identify parameters that predict progression of trunk imbalance in cases of AIS with a structural thoracolumbar/lumbar (TL/L) curve. METHODS This study included 105 patients with AIS and a structural TL/L curve who were followed up at an outpatient clinic...
September 8, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28885083/risk-factors-for-progressive-neuromuscular-scoliosis-requiring-posterior-spinal-fusion-after-selective-dorsal-rhizotomy
#15
Vijay M Ravindra, Michael T Christensen, Kaine Onwuzulike, John T Smith, Kyle Halvorson, Douglas L Brockmeyer, Marion L Walker, Robert J Bollo
OBJECTIVE Selective dorsal rhizotomy (SDR) via limited laminectomy is an effective treatment of lower-extremity spasticity in the pediatric population. Children with spasticity are also at risk for neuromuscular scoliosis; however, specific risk factors for progressive spinal deformity requiring posterior spinal fusion (PSF) after SDR are unknown. The authors' goal was to identify potential risk factors. METHODS The authors performed a retrospective cohort study of patients who underwent SDR via limited laminectomy between 2003 and 2014 and who had at least 1 year of follow-up...
September 8, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28882346/current-evidence-regarding-the-treatment-of-pediatric-lumbar-spondylolisthesis-a-report-from-the-scoliosis-research-society-evidence-based-medicine-committee
#16
Charles H Crawford, A Noelle Larson, Marilyn Gates, R Shay Bess, Tenner J Guillaume, Han Jo Kim, Matthew E Oetgen, Charles G Ledonio, James Sanders, Douglas C Burton
STUDY DESIGN: Structured literature review. OBJECTIVES: The Scoliosis Research Society requested an assessment of the current state of peer-reviewed evidence regarding pediatric lumbar spondylolisthesis to identify what is known and what research remains essential to further understanding. SUMMARY OF BACKGROUND DATA: Pediatric lumbar spondylolisthesis is common, yet no formal synthesis of the published literature regarding treatment has been previously performed...
September 2017: Spine Deformity
https://www.readbyqxmd.com/read/28880606/fibular-lengthening-osteotomy-to-correct-a-malunited-ankle-fracture-using-fresh-frozen-femoral-head-allograft
#17
Harry J Visser, Khawar Malik, Robert A Djali
Malreduction of a distal fibular fracture can lead to degenerative changes in the ankle joint. Previous studies have shown that the selective use of various fibular reconstructive osteotomies may halt the progression of degenerative arthritis by restoring the normal tibiotalar contact area and decreasing the stresses on the articular cartilage. In this case report, we achieved alignment with restoration of the talocrural angle and Shenton's line of the ankle using a transfibular osteotomy and an allogeneic fresh-frozen femoral head graft to fill the resultant defect...
July 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28880193/beyond-pairwise-matching-person-reidentification-via-high-order-relevance-learning
#18
Xibin Zhao, Nan Wang, Yubo Zhang, Shaoyi Du, Yue Gao, Jiaguang Sun
Person reidentification has attracted extensive research efforts in recent years. It is challenging due to the varied visual appearance from illumination, view angle, background, and possible occlusions, leading to the difficulties when measuring the relevance, i.e., similarities, between probe and gallery images. Existing methods mainly focus on pairwise distance metric learning for person reidentification. In practice, pairwise image matching may limit the data for comparison (just the probe and one gallery subject) and yet lead to suboptimal results...
August 31, 2017: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/28878468/the-effect-of-changing-condition-of-walking-speed-on-the-knee-angle-of-rats-with-osteoarthritis
#19
Chan-Woo Nam, Kyoung Kim, Sang-Su Na
[Purpose] The purpose of this study was to investigate the positive effect of exercise on knee osteoarthritis in rats with osteoarthritis induced by applying effective walking speed when changing speed conditions during walking. [Subjects and Methods] The rats used in this study were male Sprague-Dawley rats weighing 300 g and 7 weeks old, and 20 rats were used. The Osteoarthritis (OA) rats model was induced by MIA (monoiodoacetate). The rats was randomly divided into experimental group (MIA injection group) and control group (normal cell line injection group)...
August 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28877703/influence-of-growth-hormone-treatment-on-radiographic-indices-of-the-spine-propensity-matched-analysis
#20
Yeo-Hon Yun, Soon-Sun Kwon, Youngdo Koh, Dong-Jun Kim, Jonghyun Ahn, Seung Yeol Lee
BACKGROUND: We performed this study to investigate the influence of recombinant human growth hormone (rhGH) therapy on radiographic indices of the spine using propensity-matched analysis. METHODS: Patients with idiopathic short stature who had undergone both growth hormone therapy and whole-spine radiographs more than twice prior to 15 years of age were included in the patient group. Other patients who had undergone whole-spine radiographs more than twice prior to the same age during regular checkups for idiopathic scoliosis formed the control group...
September 6, 2017: Journal of Orthopaedic Surgery and Research
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