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https://www.readbyqxmd.com/read/28227706/skin-mounted-accelerometer-system-for-measuring-knee-range-of-motion
#1
Ryan S McGinnis, Shyamal Patel, Ikaro Silva, Nikhil Mahadevan, Steve DiCristofaro, Elise Jortberg, Melissa Ceruolo, A J Aranyosi, Ryan S McGinnis, Shyamal Patel, Ikaro Silva, Nikhil Mahadevan, Steve DiCristofaro, Elise Jortberg, Melissa Ceruolo, A J Aranyosi, A J Aranyosi, Melissa Ceruolo, Ikaro Silva, Steve DiCristofaro, Elise Jortberg, Ryan S McGinnis, Shyamal Patel, Nikhil Mahadevan
Sufficient range of motion of the knee joint is necessary for performing many activities of daily living. Ambulatory monitoring of knee function can provide valuable information about progression of diseases like knee osteoarthritis and recovery after surgical interventions like total knee arthroplasty. In this paper, we describe a skin-mounted, conformal, accelerometer-based system for measuring knee angle and range of motion that does not require a skilled operator to apply devices. We establish the accuracy of this technique with respect to clinical gold standard goniometric measurements on a dataset collected from normative subjects during the performance of repeated bouts of knee flexion and extension tests...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225726/computer-assisted-retinal-vessel-tortuosity-evaluation-in-novel-mutation-fabry-disease-towards-new-prognostic-markers
#2
Irene San Román, María-Elena Rodríguez, Orsola Caporossi, Claudia Zoppetti, Andrea Sodi, Alessandro Mecocci, David López, Beatriz Rodríguez, Juan-Ramón Gimeno
PURPOSE: Fabry disease is a rare lysosomal storage disorder with systemic involvement. The authors report on a large Fabry family with GLA p.M187R mutation and exhaustive ophthalmologic assessment. METHODS: Comprehensive systemic evaluation and genetic diagnosis were performed. Ophthalmologic evaluation included intraocular pressure/visual acuity measurement, refractometry, slit lamp examination, retinography, and optical coherence tomography. Three parameters quantified retinal vessel tortuosity: sum of angle metrics, product of angle distance, and triangular index...
March 2017: Retina
https://www.readbyqxmd.com/read/28224442/report-of-the-primary-outcomes-for-gait-mechanics-in-men-of-the-acl-sports-trial-secondary-prevention-with-and-without-perturbation-training-does-not-restore-gait-symmetry-in-men-1-or-2-years-after-acl-reconstruction
#3
Jacob John Capin, Ryan Zarzycki, Amelia Arundale, Kathleen Cummer, Lynn Snyder-Mackler
BACKGROUND: Movement asymmetries during walking are common after anterior cruciate ligament (ACL) injury and reconstruction and may influence the early development of posttraumatic osteoarthritis. Preoperative neuromuscular training (like perturbation training, which is neuromuscular training requiring selective muscle activation in response to surface perturbations) improves gait asymmetries and functional outcomes among people who are ACL-deficient, but the effect of postoperative perturbation training on gait mechanics after ACL reconstruction is unknown...
February 21, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28222170/biomechanical-investigation-of-two-plating-systems-for-medial-column-fusion-in-foot
#4
Paul Simons, Theresia Sommerer, Ivan Zderic, Dieter Wahl, Mark Lenz, Hristo Skulev, Matthias Knobe, Boyko Gueorguiev, R Geoff Richards, Kajetan Klos
BACKGROUND: Arthrodesis of the medial column (navicular, cuneiform I and metatarsal I) is performed for reasons such as Charcot arthropathy, arthritis, posttraumatic reconstruction or severe pes planus. However, the complication rate is still high and mainly resulting from inadequate fixation. Special plates, designed for medial column arthrodesis, seem to offer potential to reduce the complication rate. The aim of this study was to investigate biomechanically plantar and dorsomedial fusion of the medial column using two new plating systems...
2017: PloS One
https://www.readbyqxmd.com/read/28221333/idiopathic-bilateral-profound-hypotony-in-an-unknown-progressive-neurodegenerative-disorder
#5
Lorraine M Provencher, Pamela C Carter, Wallace L M Alward
PURPOSE: To present a unique case of idiopathic bilateral hypotony in a patient with progressive, undiagnosed neurological decline, possibly due to mitochondrial disease, and to explore mechanisms of disease and potential treatment options. METHODS: This is a case report. PATIENT: A 17-year-old boy with a history of chronic progressive bilateral vision loss and hypotony in the setting of progressive gait abnormalities, lower extremity spasticity, nystagmus, and urinary retention starting around age 8...
February 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28221332/sustained-resolution-of-macular-retinoschisis-after-trabeculectomy-in-a-patient-with-progressive-glaucoma
#6
Rany Woo, Handan Akil, Nicole Koulisis, Lisa C Olmos de Koo, James C H Tan
PURPOSE: To evaluate the clinical characteristics of a patient with primary open-angle glaucoma in whom macular retinoschisis resolved completely after trabeculectomy consistently lowered intraocular pressure (IOP). METHODS: A single case report. RESULTS: We report a case of retinoschisis involving the macula in a patient with primary open-angle glaucoma in the absence of myopic maculopathy, optic nerve anomaly, or x-linked retinoschisis. The patient's glaucoma was associated with progressive visual field loss in the setting of IOP fluctuations related to posture...
February 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28221258/endoillumination-assisted-modified-scleral-buckling
#7
Alexandre Assi, Youssef Abdelmassih, Sylvain El-Khoury
PURPOSE: To assess the anatomical and functional outcomes in addition to complications for endoillumination-assisted modified scleral buckling surgery using a noncontact Oculus BIOM wide-angle viewing system in patients with primary rhegmatogenous retinal detachment. METHODS: This is an interventional prospective noncomparative case series. Consecutive patients listed for scleral buckle surgery for primary rhegmatogenous retinal detachment were enrolled over an 18-month period and followed up for 1 year...
February 17, 2017: Retina
https://www.readbyqxmd.com/read/28218375/retrieval-and-radiographic-analysis-of-the-contour-antiprotrusio-cage
#8
Jonathan M Vigdorchik, Richard S Yoon, Susannah L Gilbert, Joseph D Lipman, Mathias P Bostrom
INTRODUCTION: Acetabular reconstruction in the setting of severe bone loss or pelvic discontinuity remains a challenging problem. Multiple methods of treatment have been described including antiprotrusio cages (APCs). The objective of this study is to combine biomechanical analysis of retrieved APCs with radiographic and clinical data to determine which factors influence or predict APC failure. METHODS: 41 APCs were identified. Sequential radiographs were examined for cage and polyethylene cup abduction angles, change in centre of rotation, screw placement, progression of cage failure, and failure mechanism...
February 8, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28212675/sex-differences-in-the-association-of-skin-advanced-glycation-endproducts-with-knee-osteoarthritis-progression
#9
Charles B Eaton, Maria Sayeed, Syeda Ameernaz, Mary B Roberts, John D Maynard, Jeffrey B Driban, Timothy E McAlindon
BACKGROUND: The accumulation of advanced glycation endproducts in articular cartilage has been suggested as an etiologic factor in the development and progression of knee osteoarthritis (KOA). METHODS: We conducted a prospective cohort study of skin advanced glycation endproducts (sAGEs) measured non-invasively by skin intrinsic fluorescence and the relationship between sAGE KOA progression in 160 men and 287 women in a sub-cohort of the Osteoarthritis Initiative at a single site...
February 17, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28211469/soil-wettability-can-be-explained-by-the-chemical-composition-of-particle-interfaces-an-xps-study
#10
Susanne K Woche, Marc-O Goebel, Robert Mikutta, Christian Schurig, Matthias Kaestner, Georg Guggenberger, Jörg Bachmann
Soil wettability (quantified in terms of contact angle, CA) is crucial for physical, chemical, and biological soil functioning. As the CA is determined by components present within the outmost nanometer of particles, this study applied X-ray photoelectron spectroscopy (XPS) with a maximum analysis depth of 10 nm to test the relationship between CA and surface elemental composition, using soil samples from a chronosequence where CA increased from 0° (0 yrs) to about 98° (120 yrs). Concurrently, as seen by XPS, C and N content increased and the content of O and the mineral-derived cations (Si, Al, K, Na, Ca, Mg, Fe) decreased...
February 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28210027/klapp-method-effect-on-idiopathic-scoliosis-in-adolescents-blind-randomized-controlled-clinical-trial
#11
Diego De Sousa Dantas, Sanderson José Costa De Assis, Marina Pegoraro Baroni, Johnnatas Mikael Lopes, Enio Walker Azevedo Cacho, Roberta De Oliveira Cacho, Silvana Alves Pereira
[Purpose] To estimate the effect of Klapp method on idiopathic scoliosis in school students. [Subjects and Methods] A single-blind randomized clinical trial with 22 students randomly divided into intervention group (n=12) and inactive control group (n=10). Exercise protocol consisted of Klapp method, 20 sessions, three times a week for intervention group, and inactivity for control group. Dorsal muscle strength was measured by dynamometer; body asymmetries and gibbosity angles were measured by biophotogrammetry...
January 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28209976/voltage-induced-magnetization-dynamics-in-cofeb-mgo-cofeb-magnetic-tunnel-junctions
#12
Katsuya Miura, Shin Yabuuchi, Masaki Yamada, Masahiko Ichimura, Bivas Rana, Susumu Ogawa, Hiromasa Takahashi, Yasuhiro Fukuma, Yoshichika Otani
Recent progress in magnetic tunnel junctions (MTJs) with a perpendicular easy axis consisting of CoFeB and MgO stacking structures has shown that magnetization dynamics are induced due to voltage-controlled magnetic anisotropy (VCMA), which will potentially lead to future low-power-consumption information technology. For manipulating magnetizations in MTJs by applying voltage, it is necessary to understand the coupled magnetization motion of two magnetic (recording and reference) layers. In this report, we focus on the magnetization motion of two magnetic layers in MTJs consisting of top layers with an in-plane easy axis and bottom layers with a perpendicular easy axis, both having perpendicular magnetic anisotropy...
February 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28207895/the-metastasis-suppressor-kiss1-is-an-intrinsically-disordered-protein-slightly-more-extended-than-a-random-coil
#13
Alain Ibáñez de Opakua, Nekane Merino, Maider Villate, Tiago N Cordeiro, Georgina Ormaza, Marta Sánchez-Carbayo, Tammo Diercks, Pau Bernadó, Francisco J Blanco
The metastasis suppressor KISS1 is reported to be involved in the progression of several solid neoplasias, making it a promising molecular target for controlling their metastasis. The KISS1 sequence contains an N-terminal secretion signal and several dibasic sequences that are proposed to be the proteolytic cleavage sites. We present the first structural characterization of KISS1 by circular dichroism, multi-angle light scattering, small angle X-Ray scattering and NMR spectroscopy. An analysis of the KISS1 backbone NMR chemical shifts does not reveal any preferential conformation and deviation from a random coil ensemble...
2017: PloS One
https://www.readbyqxmd.com/read/28207617/is-brace-treatment-appropriate-for-adolescent-idiopathic-scoliosis-patients-refusing-surgery-with-cobb-angle-between-40-and-50-degrees
#14
Zezhang Zhu, Leilei Xu, Long Jiang, Xu Sun, Jun Qiao, Bang-Ping Qian, Saihu Mao, Yong Qiu
STUDY DESIGN: A retrospective study to determine whether brace treatment is appropriate for adolescent idiopathic scoliosis patients with Cobb angle between 40 and 50 degrees who utterly refuse surgery. OBJECTIVE: To investigate whether it is possible to halt the curve progression of adolescent idiopathic scoliosis patients with Cobb angle between 40 and 50 degrees through bracing, and to identify factors that could influence the effectiveness of brace treatment in such patients...
March 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28203594/foot-progression-angle-walking-test-a-dynamic-diagnostic-assessment-for-femoroacetabular-impingement-and-hip-instability
#15
Anil S Ranawat, Michael A Gaudiani, Pablo A Slullitel, James Satalich, Brian J Rebolledo
BACKGROUND: Determining an accurate clinical diagnosis for nonarthritic hip pain may be challenging, as symptoms related to femoroacetabular impingement (FAI) or hip instability can be difficult to elucidate with current testing methods. In addition, commonly utilized physical examination maneuvers are static and do not include a dynamic or weightbearing assessment to reproduce activity-related symptoms. Therefore, implementing a dynamic assessment for FAI and hip instability could help to improve diagnostic accuracy for routine clinical examinations of patients with nonarthritic hip pain...
January 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28196733/the-proportion-of-individuals-likely-to-benefit-from-customized-optic-nerve-head-structure-function-mapping
#16
Allison M McKendrick, Jonathan Denniss, Ya Xing Wang, Jost B Jonas, Andrew Turpin
PURPOSE: Interindividual variance in optic nerve head (ONH) position, axial length, and location of the temporal raphe suggest that customizing mapping between visual field locations and ONH sectors for individuals may be clinically useful. Herein we quantify the proportion of the population predicted to have structure-function mappings that markedly deviate from "average," and thus would benefit from customized mapping. DESIGN: Database study and case report. PARTICIPANTS: Population database of 2836 eyes from the Beijing Eye Study and a single case report of an individual with primary open-angle glaucoma...
February 10, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28196731/natural-history-of-conversion-of-leber-s-hereditary-optic-neuropathy-a-prospective-case-series
#17
Tiffany Jean Hwang, Rustum Karanjia, Milton Nunes Moraes-Filho, Jesse Gale, Jeffrey Show Tran, Edward R Chu, Solange R Salomao, Adriana Berezovsky, Rubens Belfort, Milton Nunes Moraes, Federico Sadun, Anna Maria DeNegri, Chiara La Morgia, Piero Barboni, Carolina do V F Ramos, Carlos Filipe Chicani, Peter A Quiros, Valerio Carelli, Alfredo A Sadun
PURPOSE: To illustrate the natural history of Leber's hereditary optic neuropathy (LHON). DESIGN: Prospective observational case series. PARTICIPANTS: The Soave-Brazil pedigree of m.11778G>A/ND4 mitochondrial DNA LHON mutation. METHODS: A prospectively acquired database of the Soave-Brazil pedigree was reviewed. Data from 285 individuals were included in the database over a 15-year period. The pedigree was reviewed for unaffected mutation carriers who converted to affected status, 6 patients with LHON were identified...
February 10, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28195497/incisor-and-molar-overjet-arch-contraction-and-molar-relationship-in-the-mixed-dentition-in-repaired-complete-unilateral-cleft-lip-and-palate-a-qualitative-and-quantitative-appraisal
#18
Suteeta Disthaporn, Sunjay Suri, Bruce Ross, Bryan Tompson, Diogenes Baena, David Fisher, Wendy Lou
OBJECTIVE: To compare the mixed dentition incisor and molar overjet, severity of contraction of the dental arch, and the sagittal molar relationship on the cleft side vs the noncleft side in children with repaired complete unilateral cleft of the lip and palate (UCLP). MATERIALS AND METHODS: Orthodontic records taken prior to orthodontic preparation for alveolar bone grafting were screened to select study casts from patients with nonsyndromic repaired complete UCLP who did not have mandibular skeletal or dental asymmetry...
February 14, 2017: Angle Orthodontist
https://www.readbyqxmd.com/read/28194709/high-survivorship-and-little-osteoarthritis-at-10-year-followup-in-scfe-patients-treated-with-a-modified-dunn-procedure
#19
Kai Ziebarth, Milan Milosevic, Till D Lerch, Simon D Steppacher, Theddy Slongo, Klaus A Siebenrock
BACKGROUND: The modified Dunn procedure has the potential to restore the anatomy in hips with slipped capital femoral epiphyses (SCFE) while protecting the blood supply to the femoral head and minimizing secondary impingement deformities. However, there is controversy about the risks associated with the procedure and mid- to long-term data on clinical outcomes, reoperations, and complications are sparse. QUESTIONS/PURPOSES: Among patients treated with a modified Dunn procedure for SCFE, we report on (1) hip pain and function as measured by the Merle d'Aubigné and Postel score, Drehmann sign, anterior impingement test, limp, and ROM; (2) the cumulative survivorship at minimum 10-year followup with endpoints of osteoarthritis (OA) progression (at least one Tönnis grade), subsequent THA, or a Merle d'Aubigné and Postel score < 15; (3) radiographic anatomy of the proximal femur measured by slip angle, α angle, Klein line, and sphericity index; and (4) the risk of subsequent surgery and complications...
February 13, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28189095/effects-of-toe-out-and-toe-in-gait-with-varying-walking-speeds-on-knee-joint-mechanics-and-lower-limb-energetics
#20
Soobia Saad Khan, Saad Jawaid Khan, Juliana Usman
Toe-out/-in gait has been prescribed in reducing knee joint load to medial knee osteoarthritis patients. This study focused on the effects of toe-out/-in at different walking speeds on first peak knee adduction moment (fKAM), second peak KAM (sKAM), knee adduction angular impulse (KAAI), net mechanical work by lower limb as well as joint-level contribution to the total limb work during level walking. Gait analysis of 20 healthy young adults was done walking at pre-defined normal (1.18m/s), slow (0.85m/s) and fast (1...
January 27, 2017: Gait & Posture
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