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https://www.readbyqxmd.com/read/29925111/prenatal-care-and-hypertensive-gestational-syndromes-a-systematic-review
#1
Gláucya Raquel Souza da Fonsêca Dutra, Laio da Costa Dutra, Gabriela Karine Souza da Fonsêca, Mauro Bezerra do Nascimento Júnior, Eudes Euler de Souza Lucena
OBJECTIVE:  Evaluate the influence of prenatal care on the occurrence of gestational hypertension. METHODS:  The Web of Science, Scopus, Pubmed, Cochrane and ClinicalTrials electronic databases were searched for articles published between January 1st , 2012 and December 31st , 2016. No language restrictions were imposed. The following keywords were used: prenatal care, medical assistance, prenatal education, pregnancy-induced hypertension. The preferred reporting items for systematic reviews and meta-analyses (PRISMA) checklist was employed...
June 20, 2018: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29925099/a-systematic-review-on-promoting-adherence-to-antiretroviral-therapy-in-hiv-infected-patients-using-mobile-phone-technology
#2
Yuri Quintana, Eduardo A Gonzalez Martorell, Darren Fahy, Charles Safran
OBJECTIVE:  Adherence to antiretroviral therapy (ART) is paramount to successful long-term suppression of human immunodeficiency virus (HIV). For poorly adherent patients with HIV, barriers to remaining adherent may be overcome by the implementation of targeted interventions delivered via mobile devices. This systematic review is focused specifically on mobile phone technologies to deliver adherence interventions in HIV/acquired immunodeficiency syndrome (AIDS) populations. METHODS:  This review (PROSPERO #CRD42017065131) systematically extracted data from published literature from five databases on mobile phone interventions to improve adherence to ART for HIV...
April 2018: Applied Clinical Informatics
https://www.readbyqxmd.com/read/29925097/-quality-and-satisfaction-with-the-surgical-medical-clerkship-from-a-student-perspective
#3
Susanne Froehlich, Florian Goebel, Adrian Meder, Janine Wirkner, Udo Obertacke, Richard Kasch
PREFACE: The surgical medical clerkship is of special importance, as the student is given the opportunity to get in touch with medical colleagues and patients for the first time, and the interest in a certain field of specialisation can be consolidated. The present study will clarify how students perceived their medical clerkship in the field of surgery. METHODS: A nationwide online survey carried out in 2012 was able to recruit 9079 participants, and contained questions about the completed curricular internships...
June 20, 2018: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29925085/the-conduct-of-australian-indigenous-primary-health-care-research-focusing-on-social-and-emotional-wellbeing-a-systematic-review
#4
Sara Farnbach, Anne-Maree Eades, Josephine D Gwynn, Nick Glozier, Maree L Hackett
Objectives and importance of study: Values and ethics: guidelines for ethical conduct in Aboriginal and Torres Strait Islander health research (Values and ethics) describes key values that should underpin Aboriginal and Torres Strait Islander (Indigenous)-focused health research. It is unclear how research teams address this document in primary health care research. We systematically review the primary health care literature focusing on Indigenous social and emotional wellbeing (SEWB) to identify how Values and ethics and community preferences for standards of behaviour (local protocols) are addressed during research...
June 14, 2018: Public Health Research & Practice
https://www.readbyqxmd.com/read/29925044/a-systematic-review-of-patient-reported-outcomes-in-phase-ii-or-iii-clinical-trials-of-myelodysplastic-syndromes-and-acute-myeloid-leukemia
#5
REVIEW
Ashley Leak Bryant, Sarah W Drier, Sejin Lee, Antonia V Bennett
The purpose of this systematic literature review was to identify clinical trials of MDS and AML that included patient-reported outcome (PRO) instruments, and to summarize the symptom and other health related quality of life (HRQOL) concepts most frequently assessed and the PRO instruments that were used. Sixteen manuscripts describing 14 distinct trials met all criteria (i.e., phase 2 or 3 clinical trial for MDS or AML which included PRO assessment) and were published between 1996-2017. In trials evaluating anemia, PRO scores showed significant improvement in relevant domains (e...
June 7, 2018: Leukemia Research
https://www.readbyqxmd.com/read/29924837/barriers-and-facilitators-for-gps-in-dementia-advance-care-planning-a-systematic-integrative-review
#6
Bram Tilburgs, Myrra Vernooij-Dassen, Raymond Koopmans, Hans van Gennip, Yvonne Engels, Marieke Perry
BACKGROUND: Due to the disease's progressive nature, advance care planning (ACP) is recommended for people with early stage dementia. General practitioners (GPs) should initiate ACP because of their longstanding relationships with their patients and their early involvement with the disease, however ACP is seldom applied. AIM: To determine the barriers and facilitators faced by GPs related to ACP with people with dementia. DATA SOURCES: We systematically searched the relevant databases for papers published between January 1995 and December 2016, using the terms: primary healthcare, GP, dementia, and ACP...
2018: PloS One
https://www.readbyqxmd.com/read/29924758/non-syndromic-craniosynostosis-in-children-scoping-review
#7
A Garrocho-Rangel, L Manríquez-Olmos, J Flores-Velázquez, M-A Rosales-Berber, R Martínez-Rider, A Pozos-Guillén
BACKGROUND: Craniosynostosis (CS) is a complex condition consisting of the early fusion of one or more cranial sutures in the intrauterine stage. The affected infant exhibits abnormal head shape at time of birth or shortly thereafter. It can be observed in normal individuals (non-syndromic CS or NSCS) or as a part of a multisystem syndrome. The purposes of the present article were to carry out a scoping review on Non-Syndromic CS and to discuss the most important findings retrieved. MATERIAL AND METHODS: The steps of this scoping review were as follows: first, to pose a research question; second, to identify relevant studies to answer the research question; third, to select and retrieve the studies; fourth, to chart the critical data, and finally, to collate, summarize, and report the results from the most important articles...
June 20, 2018: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29924754/oral-lesions-in-sj%C3%A3-gren-s-syndrome-a-systematic-review
#8
J Serrano, R-M López-Pintor, J González-Serrano, M Fernández-Castro, E Casañas, G Hernández
BACKGROUND: Sjögren's syndrome (SS) is an autoimmune disease related to two common symptoms: dry mouth and eyes. Although, xerostomia and hyposialia have been frequently reported in these patients, not many studies have evaluated other oral manifestations. The aim of this systematic review was to investigate prevalence rates of oral lesions (OL) in SS patients and to compare it to a control group (CG), when available. MATERIAL AND METHODS: An exhaustive search of the published literature of the Pubmed, Scopus, Web of Science and the Cochrane Library databases was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) for relevant studies that met our eligibility criteria (up to September 1st 2017)...
June 20, 2018: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29924695/exposing-school-employee-sexual-abuse-and-misconduct-shedding-light-on-a-sensitive-issue
#9
Molly M Henschel, Billie-Jo Grant
While the media continue to report incidents of school employee sexual misconduct, few empirical studies focus on this issue. To address this gap in the literature, expand knowledge and awareness around the problem, and inform future research and programs, this research intends to document and analyze the characteristics of school employee sexual misconduct cases reported in the media. The authors conducted a landscape analysis of 361 published school employee sexual misconduct cases in the United States from 2014, documenting factors such as offender and victim characteristics, type of incident, technology use, location of offense, and resulting disciplinary actions by schools and law enforcement...
June 20, 2018: Journal of Child Sexual Abuse
https://www.readbyqxmd.com/read/29924497/cyp2e1-rsa-%C3%AE-pst-%C3%AE-polymorphism-and-lung-cancer-susceptibility-a-meta-analysis-involving-10-947-subjects
#10
Ze-Tian Shen, Xin-Hu Wu, Bing Li, Jun-Shu Shen, Zhen Wang, Jing Li, Xi-Xu Zhu
The above article, published in the Journal of Cellular and Molecular Medicine on 14 September 2016 in Wiley Online Library (wileyonlinelibrary.com), and in Volume 19, pp. 2136-2142, has been retracted by agreement between the authors, the journal Editor in Chief, Stefan Constantinescu, and John Wiley & Sons Ltd. The retraction has been agreed due to unattributed overlap of the language used in the "Materials and method" and "Discussion" sections of this study and the following article published in Lung Cancer: "CYP2E1 Rsa I/Pst I polymorphism is associated with lung cancer risk among Asians" by Ping Zhan, Jing Wang, Yu Zhang, Li-Xin Qiu, Su-feng Zhao, Qian Qian, Shu-Zhen Wei, Li-Ke Yu and Yong Song, Volume 69, 2010, pages 19-25...
July 2018: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/29924388/fat-supplementation-of-human-milk-for-promoting-growth-in-preterm-infants
#11
REVIEW
Emma A Amissah, Julie Brown, Jane E Harding
BACKGROUND: As preterm infants do not experience the nutrient accretion and rapid growth phase of the third trimester of pregnancy, they are vulnerable to postnatal nutritional deficits, including of fat. Consequently, they require higher fat intakes compared to their full term counterparts to achieve adequate growth and development. Human milk fat provides the major energy needs of the preterm infant and also contributes to several metabolic and physiological functions. Although human milk has many benefits for this population, its fat content is highly variable and may be inadequate for their optimum growth and development...
June 19, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29924349/aesthetic-journeys-a-review-of-cosmetic-surgery-tourism
#12
Ryan Terence Pereira, Carmel M Malone, Gerard T Flaherty
Background: Medical tourism has witnessed significant growth in recent years. The emerging trend towards international travel for cosmetic surgical interventions has not previously been reviewed. The current review aims to critically address the scale and impact of cosmetic surgical tourism and to delineate the complication profile of this form of medical tourism. Methods: Articles published in the English language on the PubMed database that were relevant to surgical tourism and the complications of elective surgical procedures abroad were examined...
June 1, 2018: Journal of Travel Medicine
https://www.readbyqxmd.com/read/29924306/clinical-relevance-of-genetic-variants-of-gonadotrophins-and-their-receptors-in-controlled-ovarian-stimulation-a-systematic-review-and-meta-analysis
#13
Carlo Alviggi, Alessandro Conforti, Daniele Santi, Sandro C Esteves, Claus Yding Andersen, Peter Humaidan, Paolo Chiodini, Giuseppe De Placido, Manuela Simoni
BACKGROUND: Genotype has been implicated in the outcome of ovarian stimulation. The analysis of patient-specific genotypes might lead to an individualized pharmacogenomic approach to controlled ovarian stimulation (COS). However, the validity of such an approach remains to be established. OBJECTIVE AND RATIONALE: To define the impact of specific genotype profiles of follicle-stimulating hormone, luteinizing hormone and their receptors (FSHR, LHR and LHCGR) on ovarian stimulation outcome...
June 18, 2018: Human Reproduction Update
https://www.readbyqxmd.com/read/29924202/glaucoma-due-to-ciliary-body-cysts-and-pseudoplateau-iris-a-systematic-review-of-the-literature
#14
Tiago Ribeiro Schmalfuss, Egidio Picetti, Helena Messinger Pakter
The diagnosis of angle-closure glaucoma secondary to iridociliary cysts is challenging and lacks compiled literature support. We present a rare case of bilateral angle-closure glaucoma associated with pseudoplateau iris due to multiple ciliary cysts and conducted a systematic review of the literature to find similar case reports published between November 2006 and November 2016. Only 19 case reports present treatment modalities, and most cases required more than one therapeutic approach for controlling the intraocular pressure...
June 2018: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/29924046/generalization-of-the-right-acute-stroke-promotive-strategies-in-reducing-delays-of-intravenous-thrombolysis-for-acute-ischemic-stroke-a-meta-analysis
#15
Qiang Huang, Jing-Ze Zhang, Wen-Deng Xu, Jian Wu
The generalization of successful efforts for reducing time delays in intravenous thrombolysis (IVT) could help facilitate its utility and benefits in acute ischemic stroke (AIS) patients.We searched the PubMed and Embase databases for articles reporting interventions to reduce time delays in IVT, published between January 1995 and September 2017. The IVT rate was chosen as the primary outcome, while the compliance rates of onset-to-door time (prehospital delay) and door-to-needle time (in-hospital delay) within the targeted time frame were the secondary outcomes...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29923984/clinicopathological-and-prognostic-significance-of-pd-l1-expression-in-sarcoma-a-systematic-review-and-meta-analysis
#16
Chuanxi Zheng, Wei You, Peng Wan, Xiaochun Jiang, Jinquan Chen, Yuchen Zheng, Wei Li, Jifeng Tan, Shiquan Zhang
Programmed cell death-ligands 1 (PD-L1) is a key immune checkpoint protein and a promising therapeutic target for malignancy tumor immunotherapy. The prognostic value of PD-L1 in patients with bone and soft tissue sarcoma remains controversial. Therefore, this meta-analysis is conducted to evaluate the associations of PD-L1 expression with overall survival (OS), progression-free survival (PFS), and clinicopathological characteristics of sarcomaA comprehensive literature search of PubMed, Web of Science, Embase, and Cochrane Library was conducted for relevant studies...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29923790/impact-of-inter-individual-variance-in-the-expression-of-a-radiation-responsive-gene-panel-used-for-triage
#17
S Agbenyegah, M Abend, M J Atkinson, S E Combs, K R Trott, M Port, M Majewski
In previous studies we determined a gene expression signature in baboons for predicting the severity of hematological acute radiation syndrome. We subsequently validated a set of eight of these genes in leukemia patients undergoing total-body irradiation. In the current study, we addressed the effect of intra-individual variability on the basal level of expression of those eight radiation-responsive genes identified previously, by examining baseline levels in 200 unexposed healthy human donors (122 males and 88 females with an average age of 46 years) using real-time PCR...
June 20, 2018: Radiation Research
https://www.readbyqxmd.com/read/29923756/evolution-of-fit-for-purpose-biomarker-validations-an-lba-perspective
#18
Robert J Neely
Biomarker ligand-binding assays need to be validated for use on clinical studies in the drug development process. There is not one single guidance to cover all types of biomarker assays and their intended uses. Therefore, it is up to the scientist to piece together a validation strategy based on published papers and other sources. Shown here is a summary of what to take into consideration during a validation and how to apply it for use in the drug development process.
June 20, 2018: Bioanalysis
https://www.readbyqxmd.com/read/29923750/cost-utility-analyses-in-us-orthopaedic-foot-and-ankle-surgery-a-systematic-review
#19
Aditya V Karhade, John Y Kwon
BACKGROUND: While investigations have been performed examining the quality of US-based cost-utility analyses for other orthopaedic subspecialties and have provided important insights, a similar analysis has not been performed examining the foot and ankle literature. METHODS: A systematic review of foot and ankle studies was conducted to identify cost-utility analyses published between 2000 and 2017. Of 687 studies screened by abstract, 4 cost-utility studies were identified and scored by the Quality of Health Economic Studies instrument...
June 1, 2018: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/29923683/evaluating-efsa-protection-goals-for-honey-bees-apis-mellifera-what-do-they-mean-for-pollination
#20
Simon Croft, Mike Brown, Selwyn Wilkins, Andy Hart, Graham C Smith
In recent years there has been growing concern regarding the sudden and unexplained failure of honeybee (Apis mellifera) colonies. Several factors have been suggested including pesticides. In an effort to regulate their impact guidance has been published by the European Food Safety Authority (EFSA) recommending that the magnitude of effects on exposed colonies should not exceed 7% reduction in colony size after 2 brood cycles. However, fears have been raised regarding the practicality of measuring such a loss in the field...
June 20, 2018: Integrated Environmental Assessment and Management
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