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https://www.readbyqxmd.com/read/29055290/a-qualitative-meta-synthesis-examining-the-role-of-women-in-african-american-men-s-prostate-cancer-screening-and-treatment-decision-making
#1
REVIEW
Erin M Bergner, Emily K Cornish, Kenay Horne, Derek M Griffith
OBJECTIVE: Being an African American man is a risk factor for prostate cancer and there is little consensus about the utility of screening, early detection, and the efficacy of treatment for the disease. In this context, this systematic review examines the roles women, particularly wives, play in African American men's prostate cancer screening and treatment decision-making. METHODS: We searched OVID Medline (R), CINAHL (EBSCO), PsychInfo (EBSCO), PubMED, Cochrane Library, ERIC (Firstsearch) and Web of Science to identify peer-review articles published between 1980-2016 that reported qualitative data about prostate cancer screening, diagnosis, or treatment in African American men...
October 21, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/29055243/physiological-vital-sign-ranges-in-newborns-from-34-weeks-gestation-a-systematic-review
#2
REVIEW
Michelle Paliwoda, Karen New, Mark Davies, Fiona Bogossian
CONTEXT: The birth process and the moments thereafter are a crucial time for newborns as they adapt to extra uterine life. The adaptive process begins immediately and can take a number of days to complete. The process involves initiating and maintaining respirations, thermoregulation, and the change from foetal circulation to newborn circulation. The majority of newborns successfully adapt to extra uterine life, some experience difficulty. Early warning tools may assist clinicians identify early signs of failure to adapt and/or deterioration but these are dependent on 'Normal' vital sign reference ranges for triggering an escalation of care...
October 9, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29055168/long-term-safety-of-growth-hormone-a-combined-registry-analysis
#3
Kirstine Stochholm, Wieland Kiess
OBJECTIVES: Preliminary data from the French cohort of the Safety and Appropriateness of Growth hormone treatments in Europe (SAGhE) study raised concerns regarding the safety of recombinant human GH, suggesting that GH may increase mortality and incidence of stroke in patients treated during childhood for GH deficiency or short stature. We evaluated published safety data, focusing on mortality, neoplasms, cerebrovascular events and diabetes across a number of large-scale pharmaceutical company GH registries...
October 21, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29055153/defining-the-actinic-keratosis-field-a-literature-review-and-discussion
#4
REVIEW
I Figueras Nart, R Cerio, T Dirschka, B Dréno, J T Lear, G Pellacani, K Peris, A Ruiz de Casas
BACKGROUND: Despite the chronic and increasingly prevalent nature of actinic keratosis (AK) and existing evidence supporting assessment of the entire cancerization field during clinical management, a standardized definition of the AK field to aid in the understanding and characterization of the disease is lacking. OBJECTIVES: The objective of this review is to present and appraise the available evidence describing the AK cancerization field, with the aim of determining a precise definition of the AK field in terms of its molecular (including genetic and immunological), histological, and clinical characteristics...
October 21, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29055132/gram-negative-bacterial-toe-web-infection-a-systematic-review
#5
REVIEW
Till Weidner, Jörg Tittelbach, Tanja Illing, Peter Elsner
Gram-negative bacterial toe web infection (GNBTWI) is a frequent therapeutic challenge in clinical practice with high recurrence rates and frequent need of systemic drugs. The aim of this systematic review was to provide an updated overview and evidence-based data on pathogens, risk-factors and treatment of GNBTWI along with promoting a consistent international terminology. This systematic review is based on a search in PubMed database for English and German articles published between 1980 and 2016. A total of 7 articles were considered appropriate for inclusion in this review regarding to treatment and outcome...
October 21, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29055093/our-best-2015-2017
#6
EDITORIAL
P B Persson
Publishing, as everything else these days, is living in the fast lane. From writing to printing these words, our topmost original articles will have changed. Citations bode very well for Acta Physiologica, suggesting another stark increase in our impact factor after the large leap the impact factor took last year.(1) Yet, what may interest authors and readers even more are the prospects for our Acta-Physiologica-Award, which is probably the greatest prize ever to be presented in recognition of scientific publishing...
October 21, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/29054981/immunoadsorption-in-anti-gbm-glomerulonephritis-case-report-in-a-child-and-literature-review
#7
Guillaume Dorval, Mathilde Lion, Sophie Guérin, Saoussen Krid, Louise Galmiche-Rolland, Rémi Salomon, Olivia Boyer
Antiglomerular basement membrane glomerulonephritis (anti-GBM GN) is a rare autoimmune disease that is characterized by rapidly progressive glomerulonephritis that may be associated with pulmonary hemorrhage. Anti-GBM GN is caused by autoantibodies (classically type G immunoglobulin) directed against the α3 subunit of type IV collagen. Without any appropriate treatment, the disease is generally fulminant, and patient and kidney survival is poor. The current guidelines recommend the use of plasma exchanges and immunosuppressive drugs...
October 20, 2017: Pediatrics
https://www.readbyqxmd.com/read/29054933/social-media-enabled-learning-in-emergency-medicine-a-case-study-of-the-growth-engagement-and-impact-of-a-free-open-access-medical-education-blog
#8
Simon Carley, Iain Beardsell, Natalie May, Liz Crowe, Janos Baombe, Alan Grayson, Richard Carden, Ashley Liebig, Chris Gray, Ross Fisher, Daniel Horner, Laura Howard, Richard Body
BACKGROUND: Clinicians are increasingly using social media for professional development and education. In 2012, we developed the St.Emlyn's blog, an open access resource dedicated to providing free education in the field of emergency medicine. OBJECTIVE: To describe the development and growth of this international emergency medicine blog. METHOD: We present a narrative description of the development of St.Emlyn's blog. Data on scope, impact and engagement were extracted from WordPress, Twitter and Google Analytics...
October 20, 2017: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29054887/introducing-the-new-bts-guideline-management-of-non-tuberculous-mycobacterial-pulmonary-disease-ntm-pd
#9
EDITORIAL
Charles S Haworth, R Andres Floto
The new BTS Guidelines for the management of non-tuberculous mycobacterial pulmonary disease combine the best available evidence with expert consensus to generate a set of pragmatic Guidelines, published as a supplement to this issue of Thorax, to assist in the management of these challenging infections.
November 2017: Thorax
https://www.readbyqxmd.com/read/29054830/epidemiology-of-hepatitis-c-virus-among-people-who-inject-drugs-protocol-for-a-systematic-review-and-meta-analysis
#10
Daniel J Smith, Josh Neurer, Ashly E Jordan, Holly Hagan
BACKGROUND: Hepatitis C virus (HCV) is a persistent epidemic among people who inject drugs (PWID), and PWID remain as the population experiencing the most significant impact of HCV-related morbidity and mortality worldwide. OBJECTIVE: The purpose of this systematic review and meta-analysis is to synthesize data on the epidemiology of HCV infection among PWID. Our main objectives are to characterize the global and regional distribution and determinants of HCV infection among PWID...
October 20, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29054800/aptamer-affinity-ligands-in-protein-chromatography
#11
REVIEW
Gérald Perret, Egisto Boschetti
The present review deals with the place of single chain oligonucleotide ligands (aptamers) in affinity chromatography applied to proteins. Aptamers are not the only affinity ligands available but they represent an emerging and highly promising route that advantageously competes with antibodies in immunopurification processes. A historical background of affinity chromatography from the beginning of the discipline to the most recent outcomes is first presented. Then the focus is centered on aptamers which represent the last step so far to the long quest for affinity ligands associating very high specificity, availability and strong stability against most harsh cleaning agents required in chromatography...
October 17, 2017: Biochimie
https://www.readbyqxmd.com/read/29054719/two-cases-of-distal-ulna-giant-cell-tumors-treated-by-extensive-resection-prosthetic-reconstruction-and-stabilization-using-the-brachioradialis-tendon
#12
A Thiounn, E Guerre, C Szymanski, C Maynou, C Fontaine
Aggressive giant cell tumors are rare at the distal ulna. We report the results of two patients who were treated surgically using a distal ulna prosthesis stabilized by ligament reconstruction with the brachioradialis tendon. At the maximum follow-up of 18months, the two patients were satisfied. Joint range of motion and functional scores were improved. X-rays showed no recurrence or subluxation; however gradual impingement of the ulnar notch of radius by the prosthesis was visible. Our technique seems to be a viable alternative when compared with the treatments described in other published case reports...
October 17, 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/29054690/removable-rigid-dressings-for-postoperative-management-of-transtibial-amputations-a-review-of-published-evidence
#13
REVIEW
James P Reichmann, Phillip M Stevens, John Rheinstein, Christopher D Kreulen
Forty years of clinical experience and peer reviewed research studies support the use of non-weight bearing removable rigid dressings (RRD) as an effective means of post-operative management of transtibial amputations. We reviewed the published medical evidence regarding the use of RRDs as a postoperative management strategy, culminating in an evidence-based practice recommendation. Published peer reviewed literature on the topic was searched and classified by level of evidence based on the research design utilizing the scale recommended by the PM&R Journal (level I through V)...
October 17, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29054676/is-diagnostic-performance-of-quantitative-2d-shear-wave-elastography-optimal-for-clinical-classification-of-benign-and-malignant-thyroid-nodules-a-systematic-review-and-meta-analysis
#14
Haliimah A Nattabi, Norhafidzah M Sharif, Noorazrul Yahya, Rozilawati Ahmad, Mazlyfarina Mohamad, Faizah M Zaki, Ahmad N Yusoff
RATIONALE AND OBJECTIVE: This study is a dedicated 2D-shear wave elastography (2D-SWE) review aimed at systematically eliciting up-to-date evidence of its clinical value in differential diagnosis of benign and malignant thyroid nodules. METHODS: PubMed, Web of Science, and Scopus databases were searched for studies assessing the diagnostic value of 2D-SWE for thyroid malignancy risk stratification published until December 2016. The retrieved titles and abstracts were screened and evaluated according to the predefined inclusion and exclusion criteria...
October 17, 2017: Academic Radiology
https://www.readbyqxmd.com/read/29054628/results-of-a-paired-catchment-analysis-of-forest-thinning-in-turkey-in-relation-to-forest-management-options
#15
Ibrahim Yurtseven, Yusuf Serengil, Ferhat Gökbulak, Kamil Şengönül, Süleyman Ozhan, Umit Kılıç, Betül Uygur, Mehmet Said Ozçelik
Adaptation to climate change has become a more serious concern as IPCC assessment reports estimate a rise of up to 2°C in average global temperatures by the end of the century. Several recently published studies have underlined the importance of forest management in mitigating the impacts of climate change and in supporting the adaptation capacity of the ecosystem. This study focuses on the role of water-related forest services in this adaptation process. The effects of forestry practices on streamflow can best be determined by paired watershed analysis...
October 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29054591/us-alone-trials-presented-during-acquisition-do-not-disrupt-classical-eyeblink-conditioning-empirical-and-computational-findings
#16
M T Allen, C E Myers, D Williams, R J Servatius
Studies of partial reinforcement in eyeblink conditioning have typically shown slower learning of a CS-US association when paired CS-US trials are interleaved with CS-alone trials. However, recent work has shown that CS-US learning is not slowed by interleaved US-alone trials. This discrepancy is surprising since both partial reinforcement protocols reduce the total number of paired CS-US trials. Previously, Kimble et al. (1955) reported that inserting a block of US-alone trials during CS-US training did not disrupt eyeblink acquisition...
October 17, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29054574/concepts-antecedents-and-consequences-of-ambulance-ramping-in-the-emergency-department-a-scoping-review
#17
Chris Kingswell, Ramon Z Shaban, Julia Crilly
BACKGROUND: Patients arriving at the Emergency Department (ED) via ambulance can experience a delay in receiving definitive care. In Australia, this phenomenon is referred to as 'Ambulance Ramping', 'Patient Off Stretcher Time Delay' or 'Offload Delay'. As a direct consequence of crowding, and in the context of a worldwide increase in ED and ambulance usage, hospital and ambulance service function is hampered. The aim of this review was to synthesize the literature with respect to the conceptualisation, meaning, antecedents and consequences of Ambulance Ramping...
October 17, 2017: Australasian Emergency Nursing Journal: AENJ
https://www.readbyqxmd.com/read/29054541/a-quantitative-assessment-of-the-membrane-integral-sub-proteome-of-a-bacterial-magnetic-organelle
#18
Oliver Raschdorf, Florian Bonn, Natalie Zeytuni, Raz Zarivach, Dörte Becher, Dirk Schüler
Magnetotactic bacteria produce chains of complex membrane-bound organelles that direct the biomineralization of magnetic nanoparticles and serve for magnetic field navigation. These magnetosome compartments have recently emerged as a model for studying the subcellular organization of prokaryotic organelles. Previous studies indicated the presence of specific proteins with various functions in magnetosome biosynthesis. However, the exact composition and stoichiometry of the magnetosome subproteome have remained unknown...
October 17, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/29054540/do-sport-related-concussions-result-in-long-term-cognitive-impairment-a-review-of-event-related-potential-research
#19
Christopher J Brush, Peter J Ehmann, Ryan L Olson, Walter R Bixby, Brandon L Alderman
Sport-related concussions have become a major public health concern although the long-term effects on cognitive function remain largely unknown. Event-related potentials (ERPs) are ideal for studying the long-term impact of sport-related concussions, as they have excellent temporal precision and provide insight that cannot be obtained from behavioral or neuropsychological measures alone. We reviewed all available published studies that have used stimulus or response-locked ERPs to document cognitive control processes in individuals with a history of concussion...
October 17, 2017: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/29054515/blood-transfusion-management-and-transfusion-related-outcomes-in-daratumumab-treated-patients-with-relapsed-or-refractory-multiple-myeloma
#20
Ajai Chari, Suzanne Arinsburg, Sundar Jagannath, Toshihisa Satta, Ivey Treadwell, Donna Catamero, Gillian Morgan, Huaibao Feng, Clarissa Uhlar, Imran Khan, Parul Doshi, Saad Usmani
INTRODUCTION: Daratumumab, a human CD38 monoclonal antibody approved for multiple myeloma (MM) treatment, binds red blood cells (RBCs), resulting in panagglutination in compatibility tests. Published mitigation methods avoid additional testing, ensuring timely release of blood products. Blood transfusion management and transfusion-related outcomes of daratumumab-treated patients in the SIRIUS study are reported, with emphasis on 2 clinical sites. PATIENTS AND METHODS: Patients had MM treated with ≥ 3 prior lines of therapy, including a proteasome inhibitor and an immunomodulatory drug, or were refractory to a proteasome inhibitor and an immunomodulatory drug...
September 19, 2017: Clinical Lymphoma, Myeloma & Leukemia
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