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https://www.readbyqxmd.com/read/29168997/a-retrospective-audit-of-in-hospital-30-day-mortality-from-acute-myocardial-infarction-in-connolly-hospital-blanchardstown
#1
M Hensey, M Cronin, E Keelan, J O'Neill, J Galvin
In 2015, The Department of Health published the first annual report of the "National Healthcare Quality Reporting System." Connolly Hospital was reported to a mortality rate within 30 days post-Acute Myocardial Infarction (AMI) of 9.87 per 100 cases which was statistically significantly higher than the national rate. We carried out a retrospective audit of patients who were HIPE-coded as having died within 30 days of AMI from 2011-2013 and identified 42 patients. On review, only 23 patients (54.8%) were confirmed as having had an AMI...
August 12, 2017: Irish Medical Journal
https://www.readbyqxmd.com/read/29168610/rural-placement-experiences-in-dental-education-and-the-impact-on-professional-intentions-and-employment-outcomes-a-systematic-review
#2
G Johnson, F C Wright, K Foster, A Blinkhorn
CONTEXT/INTRODUCTION: The availability of clinical dental services in rural locations is a major concern for many countries as dental care professionals gravitate to work in metropolitan areas. This systematic review examines the literature on Rural Placement Programs within dentistry and their impact on workforce intentions and employment outcomes. The review provides a detailed analysis of the methodological characteristics of the literature, considers the quality of the evidence and compares the outcomes within an international context...
November 23, 2017: European Journal of Dental Education: Official Journal of the Association for Dental Education in Europe
https://www.readbyqxmd.com/read/29168557/probiotics-for-vulvovaginal-candidiasis-in-non-pregnant-women
#3
REVIEW
Huan Yu Xie, Dan Feng, Dong Mei Wei, Ling Mei, Hui Chen, Xun Wang, Fang Fang
BACKGROUND: Vulvovaginal candidiasis (VVC) is estimated to be the second most common form of infection after bacterial vaginosis. The ability of probiotics in maintaining and recovering the normal vaginal microbiota, and their potential ability to resist Candidas give rise to the concept of using probiotics for the treatment of VVC. OBJECTIVES: To assess the effectiveness and safety of probiotics for the treatment of vulvovaginal candidiasis in non-pregnant women...
November 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29168319/hospital-based-routine-hiv-testing-in-high-income-countries-a-systematic-literature-review
#4
A Elgalib, S Fidler, K Sabapathy
OBJECTIVES: To produce a summary of the published evidence of the barriers and facilitators for hospital-based routine HIV testing in high-income countries. METHODS: Electronic databases were searched for studies, which described the offer of HIV testing to adults attending emergency departments (EDs) and acute medical units (AMUs) in the UK and US, published between 2006 and 2015. Other high-income countries were not included, as their guidelines do not recommend routine testing for HIV...
November 23, 2017: HIV Medicine
https://www.readbyqxmd.com/read/29168307/optimising-residential-respite-care-in-nursing-homes-current-problems-and-solutions-for-a-better-future
#5
Melissa Willoughby, Joseph Elias Ibrahim, Noha Ferrah, Lyndal Bugeja
AIM: To examine whether residential respite care increases the risk of harm to older people and suggest directions for future research and policy. BACKGROUND: Respite care is a vital part of the aged care system that supports dependent older people and their caregivers to continue residing in the community. There is little research determining whether an older person experiences harm from residential respite. METHODS: This commentary considered conceptual research and existing empirical evidence to determine whether the risk of death was greater during residential respite care for older people...
November 23, 2017: International Journal of Older People Nursing
https://www.readbyqxmd.com/read/29168303/fall-risk-assessment-tools-for-use-among-older-adults-in-long-term-care-settings-a-systematic-review-of-the-literature
#6
REVIEW
Susan Nunan, Christine Brown Wilson, Timothy Henwood, Deborah Parker
OBJECTIVE: To conduct a systematic review of published fall risk assessment tools (FRATs) tested for predictive validity among older adults in long-term care (LTC). METHODS: A systematic search was conducted using five databases. Only studies reporting on sensitivity and specificity values, conducted in LTC on populations primarily aged over 60 years, were considered. RESULTS: Fifteen papers were included and three different categories of FRATs emerged: multifactorial assessment tools, functional mobility assessments and algorithms...
November 23, 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/29168259/constipation-management-in-people-with-intellectual-disability-a-systematic-review
#7
REVIEW
Janet Robertson, Susannah Baines, Eric Emerson, Chris Hatton
BACKGROUND: Constipation can lead to serious health issues and death. This systematic review summarizes international research pertaining to the management of constipation in people with intellectual disability. METHOD: Studies published from 1990 to 2017 were identified using Medline, Cinahl, PsycINFO, Web of Science, email requests and cross-citations. Studies were reviewed narratively in relation to identified themes. RESULTS: Eighteen studies were reviewed in relation to three themes: laxative receipt; interventions (dietary fibre, abdominal massage and macrogol); and staff issues (knowledge and training)...
November 23, 2017: Journal of Applied Research in Intellectual Disabilities: JARID
https://www.readbyqxmd.com/read/29167719/is-khat-catha-edulis-chewing-a-risk-factor-for-periodontal-diseases-a-systematic-review
#8
REVIEW
Butchibabu Kalakonda, Sadeq-Ali Al-Maweri, Hashem-Motahir Al-Shamiri, Anum Ijaz, Shukri Gamal, Esam Dhaifullah
Background: Khat (Catha edulis) chewing is a highly prevalent habit in the Arabian Peninsula and East Africa, and has recently spread to Western countries. The association between khat chewing and oral mucosal lesions is well documented in the literature. However, there is no concrete evidence on the association between khat chewing and periodontal disease. The purpose of this systematic review was to analyze the influence of khat chewing on periodontal health. Material and Methods: A literature search of PubMed, Scopus and Web of Sciences databases was carried out to identify relevant articles published from 1990 to May 2017...
October 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29167693/approving-cancer-treatments-based-on-endpoints-other-than-overall-survival-an-analysis-of-historical-data-using-the-pace-continuous-innovation-indicators%C3%A2-cii
#9
Neon Brooks, Mario Campone, Silvia Paddock, Scott Shortenhaus, David Grainger, Jacqueline Zummo, Samuel Thomas, Rose Li
Background: There is an active debate about the role that endpoints other than overall survival (OS) should play in the drug approval process. Yet the term 'surrogate endpoint' implies that OS is the only critical metric for regulatory approval of cancer treatments. We systematically analyzed the relationship between U.S. Food and Drug Administration (FDA) approval and publication of OS evidence to understand better the risks and benefits of delaying approval until OS evidence is available...
2017: Drugs in Context
https://www.readbyqxmd.com/read/29167656/multivariate-analyses-of-balance-test-performance-vestibular-thresholds-and-age
#10
Faisal Karmali, María Carolina Bermúdez Rey, Torin K Clark, Wei Wang, Daniel M Merfeld
We previously published vestibular perceptual thresholds and performance in the Modified Romberg Test of Standing Balance in 105 healthy humans ranging from ages 18 to 80 (1). Self-motion thresholds in the dark included roll tilt about an earth-horizontal axis at 0.2 and 1 Hz, yaw rotation about an earth-vertical axis at 1 Hz, y-translation (interaural/lateral) at 1 Hz, and z-translation (vertical) at 1 Hz. In this study, we focus on multiple variable analyses not reported in the earlier study. Specifically, we investigate correlations (1) among the five thresholds measured and (2) between thresholds, age, and the chance of failing condition 4 of the balance test, which increases vestibular reliance by having subjects stand on foam with eyes closed...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29167519/publisher-correction-seismic-evidence-for-a-possible-deep-crustal-hot-zone-beneath-southwest-washington
#11
Ashton F Flinders, Yang Shen
A correction to this article has been published and is linked from the HTML version of this paper. The error has beenfixed in the paper.
November 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29167460/early-vaccination-protects-against-childhood-leukemia-a-systematic-review-and-meta-analysis
#12
Mostafa Ebraheem Morra, Nguyen Dang Kien, Ahmed Elmaraezy, Omar Ayman M Abdelaziz, Ahmed Lotfy Elsayed, Oday Halhouli, Ahmed Mosaad Montasr, Tran Le-Huy Vu, Chau Ho, Amr Sayed Foly, Anh Phan Phi, Wessam Magdy Abdullah, Marina Mikhail, Elizabeth Milne, Kenji Hirayama, Nguyen Tien Huy
Leukemia is the most commonly diagnosed childhood cancer, although its etiology is still largely unknown. Growing evidence supports a role for infection in the etiology of acute lymphocytic leukemia (ALL), and the involvement of the immune system suggests that vaccination may also play a role. However, the findings presented in the published literature are inconsistent. Therefore, we conducted a PRISMA systematic review and meta-analysis. 14 studies were identified and meta-analyzed. Vaccinations studied comprised Bacillus Calmette-Guérin (BCG) vaccine, Triple vaccine, Hepatitis B vaccine (HBV), Polio, Measles, Rubella, Mumps, trivalent MMR vaccine and Haemophilus influenza type B (HiB) vaccine...
November 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29167388/real-world-use-of-apixaban-for-stroke-prevention-in-atrial-fibrillation-a-systematic-review-and-meta-analysis
#13
Marco Proietti, Imma Romanazzi, Giulio Francesco Romiti, Alessio Farcomeni, Gregory Y H Lip
BACKGROUND AND PURPOSE: The use of oral anticoagulant therapy for stroke prevention in atrial fibrillation has been transformed by the availability of the nonvitamin K antagonist oral anticoagulants. Real-world studies on the use of nonvitamin K antagonist oral anticoagulants would help elucidate their effectiveness and safety in daily clinical practice. Apixaban was the third nonvitamin K antagonist oral anticoagulants introduced to clinical practice, and increasing real-world studies have been published...
November 22, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29167080/psychosocial-care-models-for-families-of-critically-ill-children-in-pediatric-emergency-department-settings-a-scoping-review
#14
Alys-Marie Manguy, Lynette Joubert, Ed Oakley, Rob Gordon
PROBLEM: Critical illness in children is a significant and stressful life event for families. Within pediatric emergency department (ED) settings it is acknowledged that these crises are challenging for both the families of these children, and for the clinical staff treating the child. Literature recommends routine care should include an offer to the family to be present with their critically ill child, however there is a lack of clarity regarding specific family care models or evidence-based interventions to guide clinical practice...
October 26, 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29167071/therapeutic-response-analysis-in-dogs-with-naturally-occurring-osteoarthritis
#15
Alexandre Gagnon, Dominique Brown, Maxim Moreau, Bertrand Lussier, Colombe Otis, Eric Troncy
OBJECTIVE: Reporting the rate of positive (+) and negative (-) responders based on an objective outcome measure of pain-related functional disability/lameness in dogs with naturally occurring osteoarthritis (OA), and the relationship between initial lameness severity and the odds of being a (+) responder. STUDY DESIGN: Retrospective analysis of published peer-reviewed clinical trials in dogs with naturally occurring OA. ANIMALS: Dogs (n = 213) with hip and/or stifle afflicted-joints...
September 15, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/29167065/a-systematic-review-of-practice-guidelines-and-recommendations-for-discontinuation-of-cholinesterase-inhibitors-in-dementia
#16
REVIEW
Brenna N Renn, Ali Abbas Asghar-Ali, Stephen Thielke, Angela Catic, Sharyl R Martini, Brian G Mitchell, Mark E Kunik
Cholinesterase inhibitors (ChEIs) are the primary pharmacological treatment for symptom management of Alzheimer disease (AD), but they carry known risks during long-term use, and do not guarantee clinical effects over time. The balance of risks and benefits may warrant discontinuation at different points during the disease course. Indeed, although there is limited scientific study of deprescribing ChEIs, clinicians routinely face practical decisions about whether to continue or stop medications. This review examined published practice recommendations for discontinuation of ChEIs in AD...
October 10, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29166911/effective-strategies-for-scaling-up-evidence-based-practices-in-primary-care-a-systematic-review
#17
REVIEW
Ali Ben Charif, Hervé Tchala Vignon Zomahoun, Annie LeBlanc, Léa Langlois, Luke Wolfenden, Sze Lin Yoong, Christopher M Williams, Roxanne Lépine, France Légaré
BACKGROUND: While an extensive array of existing evidence-based practices (EBPs) have the potential to improve patient outcomes, little is known about how to implement EBPs on a larger scale. Therefore, we sought to identify effective strategies for scaling up EBPs in primary care. METHODS: We conducted a systematic review with the following inclusion criteria: (i) study design: randomized and non-randomized controlled trials, before-and-after (with/without control), and interrupted time series; (ii) participants: primary care-related units (e...
November 22, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/29166434/evidence-hierarchies-relating-to-hand-surgery-current-status-and-improvement-a-bibliometric-analysis-study
#18
Thaís Silva Barroso, Marcelo Cortês Cavalcante, João Baptista Gomes Dos Santos, João Carlos Belloti, Flávio Faloppa, Vinícius Ynoe de Moraes
BACKGROUND: Hierarchy of evidence is an important measurement for assessing quality of literature. Information regarding quality of evidence within the Brazilian hand surgery setting is sparse, especially regarding whether research has improved in either quality or quantity. This study aimed to identify and classify hand surgery studies published in the two most important Brazilian orthopedics journals based on hierarchy of evidence, with comparisons with previously published data. DESIGN AND SETTING: Bibliometric analysis study performed in a federal university...
November 17, 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/29166309/surgeon-sleep-deprivation-surgical-complications-and-the-ethical-imperatives-of-evidence-based-persuasion
#19
William Lineaweaver, Scott Corlew, Feng Zhang
INTRODUCTION: A proposed relationship between surgeon sleep deprivation (SSD) and increased patient complications is examined through a review of published studies and application of standards of evidence-based persuasion. METHODS: Published studies of SSD and patient complications were analyzed to evaluate reported relationships between SSD and surgical complications. The basis of a reported "83% increase" in patient complication associated with SSD was reexamined at its original data source...
November 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29166260/the-development-and-content-validation-of-a-multidisciplinary-evidence-based-wound-infection-prevention-and-treatment-guideline
#20
Sammy A Zakhary, Chris Davey, Rebecca Bari, Jordan Bean, Tyler Reber, Kathy Gallagher, Kara Couch, Jennifer Hurlow, Karen Laforet, Corrine McIssac, Karen Napier, Diana Vilar-Compte, Emily Zakhary, Michel Hermans, Laura Bolton
Acute and chronic wound infections create clinical, economic, and patient-centered challenges best met by multidisciplinary wound care teams providing consistent, valid, clinically relevant, safe, evidence-based management across settings. To develop an evidence-based wound infection guideline, PubMed, Cochrane Library, and Cumulative Index to Nursing and Allied Health Literature databases were searched from inception through August 1, 2017 using the terms (or synonyms) wound infection and risk factor, significant, diagnosis, prevention, treatment, or surveillance...
November 2017: Ostomy/wound Management
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