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https://www.readbyqxmd.com/read/28425489/meis1-variant-as-a-determinant-of-autonomic-imbalance-in-restless-legs-syndrome
#1
Jérôme Thireau, Charlotte Farah, Nicolas Molinari, Fabrice Bouilloux, Lucas Torreilles, Juliane Winkelmann, Sabine Scholz, Sylvain Richard, Yves Dauvilliers, Frédéric Marmigère
Restless Legs Syndrome (RLS) is a genetically complex neurological disorder in which overlapping genetic risk factors may contribute to the diversity and heterogeneity of the symptoms. The main goal of the study was to investigate, through analysis of heart rate variability (HRV), whether in RLS patients the MEIS1 polymorphism at risk influences the sympathovagal regulation in different sleep stages. Sixty-four RLS patients with periodic leg movement index above 15 per hour, and 38 controls underwent one night of video-polysomnographic recording...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28391285/while-isolated-periodic-limb-movement-disorder-significantly-impacts-sleep-depth-and-efficiency-co-morbid-restless-leg-syndrome-mainly-exacerbates-perceived-sleep-quality
#2
Florent-Xavier Hardy De Buisseret, Olivier Mairesse, Johan Newell, Paul Verbanck, Daniel Neu
BACKGROUND: Restless leg syndrome (RLS) and periodic limb movement (PLM) disorder (PLMD) can affect sleep quality and interfere with daytime functioning. Whether the co-morbidity of RLS further worsens daytime symptoms, sleep architecture and quality in patients with PLMs, is not yet fully clarified. METHODS: Sleep (polysomnography) and daytime symptoms of 47 drug-free patients, assigned to isolated PLMD or co-morbid RLS subgroups, were compared to controls in a retrospective cohort-study (n = 501)...
April 8, 2017: European Neurology
https://www.readbyqxmd.com/read/28378384/short-interval-leg-movements-during-sleep-entail-greater-cardiac-activation-than-periodic-leg-movements-during-sleep-in-restless-legs-syndrome-patients
#3
Raffaele Ferri, Francesco Rundo, Alessandro Silvani, Marco Zucconi, Debora Aricò, Oliviero Bruni, Bartolo Lanuzza, Luigi Ferini-Strambi, Mauro Manconi
Periodic leg movements during sleep (PLMS) are sequences of ≥4 motor events with intermovement intervals (IMI) of 10-90 s. PLMS are a supportive diagnostic criterion for restless legs syndrome (RLS) and entail cardiac activation, particularly when associated with arousal. RLS patients also over-express short-interval leg movements during sleep (SILMS), which have IMI <10 s and are organized mainly in sequences of two movements (doublets). We tested whether the cardiac activation associated with SILMS doublets differs from that associated with PLMS in a sample of 25 RLS patients...
April 4, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28366347/sleep-disturbance-in-pediatric-patients-on-automated-peritoneal-dialysis
#4
Cláudia Gomes, Lia Oliveira, Rosário Ferreira, Carla Simão
OBJECTIVE: There are few reports describing sleep disturbance (SD) in children on automated peritoneal dialysis (APD), and they are mostly based on the application of questionnaires. As far as we know, only two studies used polysomnography (PSG), the gold standard for the diagnosis of SD. This is the first study assessing SD in children with chronic kidney disease (CKD) on APD in our country. METHODS: This was an observational and descriptive study. Children up to 18 years of age who had undergone APD for a minimum of three months were considered eligible...
April 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28364468/intervening-leg-movements-disrupt-plms-sequences
#5
Kasidet Hiranniramol, Stephany Fulda, Patrick Skeba, Christopher J Earley, Richard P Allen
Study Objectives: Periodic leg movements during sleep (PLMS) occur within a subject as a series with a remarkably stable period defined by the intermovement interval (IMI). Sometimes a non-PLMS movement occurs intervening between two PLMS. PLMS scoring rules totally ignore these intervening leg movements (iLM). This implicitly assumes an iLM results from a process sufficiently independent from the periodic process producing PLMS that it does not affect the periodicity of the surrounding PLMS...
January 1, 2017: Sleep
https://www.readbyqxmd.com/read/28349352/the-clinical-importance-of-periodic-leg-movements-in-sleep
#6
REVIEW
Michela Figorilli, Monica Puligheddu, Patrizia Congiu, Raffaele Ferri
Periodic leg movements during sleep (PLMS) are commonly found in patients with restless leg syndrome (RLS), but they may occur in other sleep disorders and several medical conditions. Their prevalence increases with age, but they can also be observed in children. During the last decades, very active research has been devoted to determine and understand the pathophysiology, associated events, and clinical significance of PLMS. This chapter tries to sum up the most relevant PLMS-related findings, focusing on the relationship between PLMS and the cardiovascular system, in order to understand the clinical implication of this complex motor phenomenon...
March 2017: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/28341521/periodic-leg-movements-during-sleep-phenotype-neurophysiology-and-clinical-significance
#7
REVIEW
Raffaele Ferri, Brian B Koo, Daniel L Picchietti, Stephany Fulda
Periodic leg movements during sleep (PLMS) are the most important objective finding in restless legs syndrome (RLS). During the last decade, PLMS have been very important for the assessment and comprehension of their pathophysiological correlates, which have been paralleled by the emergence of new computer-assisted and data-driven rules for their identification, scoring, and analysis. The present article focused on the most relevant PLMS-related findings of the last decade, and sought to provide a coherent and comprehensive overview on this enigmatic motor phenomenon...
March 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28329227/incident-cardiovascular-events-and-death-in-individuals-with-restless-legs-syndrome-or-periodic-limb-movements-in-sleep-a-systematic-review
#8
Tetyana Kendzerska, Maneesha Kamra, Brian J Murray, Mark I Boulos
Study Objectives: To systematically review the current evidence examining restless legs syndrome (RLS) and periodic limb movements in sleep (PLMS) as prognostic factors for all-cause mortality and incident cardiovascular events (CVE) in longitudinal studies published in the adult population. Methods: All English language studies (from 1947 to 2016) found through Medline and Embase, as well as bibliographies of identified articles, were considered eligible. Quality was evaluated using published guidelines...
March 1, 2017: Sleep
https://www.readbyqxmd.com/read/28285142/effects-of-hip-abduction-and-adduction-accuracy-on-post-stroke-gait
#9
Jesse C Dean, Aaron E Embry, Katy H Stimpson, Lindsay A Perry, Steven A Kautz
BACKGROUND: Gait instability often limits post-stroke function, although the mechanisms underlying this instability are not entirely clear. Our recent work has suggested that one possible factor contributing to post-stroke gait instability is a reduced ability to accurately control foot placement. The purpose of the present experiments was to investigate whether post-stroke gait function is related to the ability to accurately abduct and adduct the hip, as required for accurate foot placement...
March 2, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28279575/should-oral-iron-be-first-line-therapy-for-pediatric-restless-legs-syndrome-and-periodic-limb-movement-disorder
#10
EDITORIAL
Daniel L Picchietti
No abstract text is available yet for this article.
April 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28268364/3d-detection-of-periodic-limb-movements-in-sleep
#11
Heinrich Garn, Bernhard Kohn, Klaus Dittrich, Christoph Wiesmeyr, Gerhard Kloesch, Robert Stepansky, Markus Wimmer, Osman Ipsiroglu, Dieter Grossegger, Manuel Kemethofer, Stefan Seidel
The standard polysomnographic method for detecting periodic limb movements in sleep (PLMS) includes measuring the electromyography (EMG) signals from electrodes at the left and right tibialis anterior muscles. This procedure has disadvantages as the cabling affects the patients quality of sleep and the electrodes tend to come off during the night, deteriorating data quality. We used contactless monitoring of body movements by a 3D time-of-flight camera mounted above the bed. Changes in the 3D silhouette indicate motion...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28259410/the-use-of-infrared-thermography-and-accelerometers-for-remote-monitoring-of-dairy-cow-health-and-welfare
#12
M Stewart, M T Wilson, A L Schaefer, F Huddart, M A Sutherland
Increasing reliance on automated systems on-farm has led to a need for remote monitoring of health and welfare. We aimed to validate 2 methods that could be integrated into automated systems currently in use: infrared thermography (IRT) to measure respiration rate (RR), and accelerometers to measure the flinch, step, kick (FSK) response and assessing stress and discomfort. We monitored 22 multiparous, nonlactating, Friesian and Friesian × Jersey cows (average 5.1 yr of age) during a baseline period (2 min), a restraint in a crush (2 min), and then a recovery period after exposure to a startle (2 min)...
May 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28243157/big-data-in-sleep-medicine-prospects-and-pitfalls-in-phenotyping
#13
Matt T Bianchi, Kathryn Russo, Harriett Gabbidon, Tiaundra Smith, Balaji Goparaju, M Brandon Westover
Clinical polysomnography (PSG) databases are a rich resource in the era of "big data" analytics. We explore the uses and potential pitfalls of clinical data mining of PSG using statistical principles and analysis of clinical data from our sleep center. We performed retrospective analysis of self-reported and objective PSG data from adults who underwent overnight PSG (diagnostic tests, n=1835). Self-reported symptoms overlapped markedly between the two most common categories, insomnia and sleep apnea, with the majority reporting symptoms of both disorders...
2017: Nature and Science of Sleep
https://www.readbyqxmd.com/read/28226527/3d-detection-of-periodic-limb-movements-in-sleep
#14
Heinrich Garn, Bernhard Kohn, Klaus Dittrich, Christoph Wiesmeyr, Gerhard Kloesch, Robert Stepansky, Markus Wimmer, Osman Ipsiroglu, Dieter Grossegger, Manuel Kemethofer, Stefan Seidel, Heinrich Garn, Bernhard Kohn, Klaus Dittrich, Christoph Wiesmeyr, Gerhard Kloesch, Robert Stepansky, Markus Wimmer, Osman Ipsiroglu, Dieter Grossegger, Manuel Kemethofer, Stefan Seidel, Christoph Wiesmeyr, Gerhard Kloesch, Heinrich Garn, Osman Ipsiroglu, Manuel Kemethofer, Robert Stepansky, Dieter Grossegger, Klaus Dittrich, Markus Wimmer, Bernhard Kohn, Stefan Seidel
The standard polysomnographic method for detecting periodic limb movements in sleep (PLMS) includes measuring the electromyography (EMG) signals from electrodes at the left and right tibialis anterior muscles. This procedure has disadvantages as the cabling affects the patients quality of sleep and the electrodes tend to come off during the night, deteriorating data quality. We used contactless monitoring of body movements by a 3D time-of-flight camera mounted above the bed. Changes in the 3D silhouette indicate motion...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28215268/periodic-limb-movements-and-restless-legs-syndrome-in-children-with-a-history-of-prematurity
#15
Christopher M Cielo, Lourdes M DelRosso, Ignacio E Tapia, Sarah N Biggs, Gillian M Nixon, Lisa J Meltzer, Joel Traylor, Ji Young Kim, Carole L Marcus
INTRODUCTION: Little is known about the pediatric population at an increased risk of restless legs syndrome (RLS) and periodic limb movement disorder (PLMD). Polysomnographic data from the Caffeine for Apnea of Prematurity-Sleep (CAPS) study showed a high prevalence of elevated periodic limb movement index (PLMI) in a cohort of ex-preterm children, but the clinical importance of this finding, such as association with RLS, is unknown. We hypothesized that ex-preterm children would have a high prevalence of RLS and PLMD...
February 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28215259/reduced-afferent-induced-facilitation-of-primary-motor-cortex-excitability-in-restless-legs-syndrome
#16
P Bocquillon, C Charley-Monaca, E Houdayer, A Marques, A Kwiatkowski, P Derambure, H Devanne
Restless legs syndrome (RLS) is characterized by the association of an urge to move, and vesperal or nocturnal sensory symptoms; it is frequently associated with periodic limb movements. Evidence from imaging and electrophysiological studies suggests that RLS is linked to changes in sensorimotor integration. Nevertheless, the underlying mechanisms have not been characterized, and the cortical origin has yet to be confirmed. The objective of the present study was to establish whether or not sensorimotor integration in RLS patients is impaired in the evening...
February 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28215254/epidemiology-of-sleep-and-sleep-disorders-in-the-netherlands
#17
Gerard A Kerkhof
OBJECTIVE: There is a surging public interest in The Netherlands concerning sleep, sleep disorders and associated health. For a proper perspective, it is necessary to have reliable information on the prevalence of sleep characteristics at the national level. This study set out to assess prevalence rates and key characteristics of sleep and sleep disorders in The Netherlands. METHODS: In 2012, a nationally representative sample of 2089 individuals, aged 18-70 years, responded to a set of 48 questions, including the Holland Sleep Disorders Questionnaire, a validated questionnaire based on the International Classification of Sleep Disorders...
February 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28199705/associations-of-incident-cardiovascular-events-with-restless-legs-syndrome-and-periodic-leg-movements-of-sleep-in-older-men-for-the-outcomes-of-sleep-disorders-in-older-men-study-mros-sleep-study
#18
John W Winkelman, Terri Blackwell, Katie Stone, Sonia Ancoli-Israel, Susan Redline
No abstract text is available yet for this article.
February 11, 2017: Sleep
https://www.readbyqxmd.com/read/28195837/the-effect-of-atomoxetin-use-in-the-treatment-of-attention-deficit-hyperactivity-disorder-on-the-symptoms-of-restless-legs-syndrome-a-case-report
#19
Saliha Baykal, Melih Nuri Karakurt
Attention-deficit/hyperactivity disorder (ADHD) is frequently accompanied with sleep disorders such as obstructive sleep apnea, periodic limb movement disorder, restless legs syndrome (RLS), and circadian rhythm disorder. We have limited information about the effects of medical therapies used in the treatment of ADHD on RLS. This article discusses the effects of atomoxetine treatment on both disorders in a patient followed by diagnoses of ADHD and RLS.
March 2017: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/28192512/explosive-strength-and-endurance-adaptations-in-young-elite-soccer-players-during-two-soccer-seasons
#20
Riccardo Di Giminiani, Christiano Visca
The purpose of the present study was to investigate the explosive strength and endurance adaptations in young elite soccer players who underwent a supervised training program for a period of two years. Nineteen players, with seven years of training experience (age: 13.3 ± 0.1 years; body weight: 57.9 ± 4.9 kg; height: 168.9 ± 4.7 cm; BMI: 20.1 ± 1.1 kg/m2), voluntarily participated in the present study. The testing sessions were performed at the beginning of the preparation period in the first (T1), second (T2), and third year (T3)...
2017: PloS One
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