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https://www.readbyqxmd.com/read/28429577/investigating-general-medication-prescription-by-general-practitioners-during-a-12-month-randomized-controlled-weight-loss-trial
#1
N R Fuller, N S Lau, T P Markovic, I D Caterson
Much healthcare expenditure is on pharmaceutical drugs. Expenditure on medications has increased both in absolute terms, and as a proportion of total health expenditure. No previous studies have investigated the prescribing costs by general practitioners when managing patients during a weight loss intervention. This study evaluated the medication costs by individual class during a 1-year study in which 268 participants were randomized to one of two weight loss programmes, either standard care (SC) as defined by national guidelines, or a commercial provider (Weight Watchers) (CP)...
April 20, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28420112/the-association-between-breakfast-skipping-and-body-weight-nutrient-intake-and-metabolic-measures-among-participants-with-metabolic-syndrome
#2
Lijuan Zhang, Lorraine S Cordeiro, Jinghua Liu, Yunsheng Ma
The effect of skipping breakfast on health, especially in adults, remains a controversial topic. A secondary data analysis was conducted to examine associations between breakfast eating patterns and weight loss, nutrient intake, and metabolic parameters among participants with metabolic syndrome (MetS) (n = 240). Three randomly selected 24-h dietary recalls were collected from each participant at baseline and at the one-year visit. Skipped breakfast was seen in 32.9% at baseline and in 17.4% at the one-year visit, respectively...
April 14, 2017: Nutrients
https://www.readbyqxmd.com/read/28415067/effect-of-whey-protein-in-conjunction-with-a-caloric-restricted-diet-and-resistance-training
#3
Wesley D Dudgeon, Elizabeth P Kelley, Timothy P Scheett
Dudgeon, WD, Kelley, EP, and Scheett, TP. Effect of whey protein in conjunction with a caloric-restricted diet and resistance training. J Strength Cond Res 31(5): 1353-1361, 2017-Caloric-restricted weight loss, especially rapid weight loss, results from a decrease in both lean and fat mass (FM). The goal for many is to lose FM while retaining lean body mass (LBM) and muscular performance thus many turn to supplements. Sixteen resistance-trained men (24 ± 1.6 years of age) completed a 4 d·wk body building style split resistance training program for 8 weeks in conjunction with a pre-exercise, periexercise, and postexercise ingestion of whey protein (WHEY) nutritional supplement or carbohydrate (CON)-based nutritional supplement...
May 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28413775/an-interesting-case-of-mycoplasma-pneumonia-associated-multisystem-involvement-and-diffuse-alveolar-hemorrhage
#4
Rashmi Mishra, Edison Cano, Sindhaghatta Venkatram, Gilda Diaz-Fuentes
Severe mycoplasma pneumonia is a rare entity with only 0.5-2% of cases having a fulminant course. We present a 74-year-old woman with hypertension, diabetes mellitus and remote history of marginal zone B-cell lymphoma admitted with abdominal pain and diarrhea of 1-2 days associated with body-aches, dyspnea, dry cough and weight loss for 2-3 weeks. On physical exam, she was febrile, tachypneic, tachycardic and hypoxic on room air. Chest examination revealed diffuse crackles and end-expiratory wheezes. Laboratory tests showed anemia, acute-on-chronic kidney injury and hyaline casts and epithelial cells in the urine analysis...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28413180/role-of-hormone-sensitive-lipase-in-leptin-promoted-fat-loss-and-glucose-lowering
#5
Mikio Takanashi, Yoshino Taira, Sachiko Okazaki, Satoru Takase, Takeshi Kimura, Cheng Cheng Li, Peng Fei Xu, Akari Noda, Ichiro Sakata, Hidetoshi Kumagai, Yuichi Ikeda, Yoko Iizuka, Naoya Yahagi, Hitoshi Shimano, Jun-Ichi Osuga, Shun Ishibashi, Takashi Kadowaki, Hiroaki Okazaki
AIM: Myriad biological effects of leptin may lead to broad therapeutic applications for various metabolic diseases, including diabetes and its complications; however, in contrast to its anorexic effect, the molecular mechanisms underlying adipopenic and glucose-lowering effects of leptin have not been fully understood. Here we aim to clarify the role of hormone-sensitive lipase (HSL) in leptin's action. METHODS: Wild-type (WT) and HSL-deficient (HSLKO) mice were made hyperleptinemic by two commonly-used methods: adenovirus-mediated overexpression of leptin and continuous subcutaneous infusion of leptin by osmotic pumps...
April 12, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/28408713/the-influence-of-glucose-exposure-load-and-peritoneal-membrane-transport-on-body-composition-and-nutritional-status-changes-after-1-year-on-peritoneal-dialysis
#6
Rafaela S Caron-Lienert, Carlos E Poli-de-Figueiredo, Ana E Figueiredo, Bartira E Pinheiro da Costa, Alessandra C Pizzato, Carlo Crepaldi, Fiorenza Ferrari, Anna Giuliani, Claudio Ronco
♦Background: The characteristics of peritoneal membrane transport differ among patients, affecting the prescription of peritoneal dialysis (PD) modality and glucose exposure in order to achieve an effective dialysis. This study aims to verify the influence of glucose exposure load and peritoneal membrane transport on body composition and nutritional status changes after the first year of PD. ♦ Methods: We examined a cohort of 85 incident PD patients during the first year of treatment. We established a cut-off of 5% to define changes in dry weight (DW), lean tissue mass (LTM), and fat mass (FM)...
April 13, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/28401638/the-effects-of-high-intensity-interval-training-vs-moderate-intensity-continuous-training-on-body-composition-in-overweight-and-obese-adults-a-systematic-review-and-meta-analysis
#7
REVIEW
M Wewege, R van den Berg, R E Ward, A Keech
OBJECTIVE: The objective of this study is to compare the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) for improvements in body composition in overweight and obese adults. METHODS: Trials comparing HIIT and MICT in overweight or obese participants aged 18-45 years were included. Direct measures (e.g. whole-body fat mass) and indirect measures (e.g. waist circumference) were examined. RESULTS: From 1,334 articles initially screened, 13 were included...
April 11, 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28401087/low-dose-yeast-hydrolysate-in-treatment-of-obesity-and-weight-loss
#8
Eun Young Jung, Jong Woo Lee, Yang Hee Hong, Un Jae Chang, Hyung Joo Suh
The anti-obesity effects of yeast hydrolysate (YH) supplementation (1.0 g/d) have already been demonstrated. We investigated whether a low dose of YH (0.5 g/d, YH-500) also has the anti-obesity effects. Thirty obese women were randomly assigned to the control or YH-500 groups. After 8 weeks, weight and body mass index were significantly reduced by the YH treatment (0.5 g/d) (P<0.05). The YH-500 group lost a significant amount of body fat after the 8-week treatment: fat mass 25.9 kg (baseline) versus 23.8 kg (8th week), P<0...
March 2017: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/28399016/the-effects-of-beef-chicken-or-whey-protein-post-workout-on-body-composition-and-muscle-performance
#9
Matthew H Sharp, Ryan P Lowery, Kevin A Shields, Jason R Lane, Jocelyn L Gray, Jeremy M Partl, Daniel W Hayes, Gabriel J Wilson, Chase A Hollmer, Julie R Minivich, Jacob M Wilson
The purpose of this study was to determine the effects of post-workout consumption of beef protein isolate (Beef), hydrolyzed chicken protein (Chx) or whey protein concentrate (WPC), compared to a control on lean mass and strength during 8 weeks of resistance training. Forty-one males and females were randomized into four groups: WPC (m=5, f=5; Age (yrs)=19 ± 2, Height (cm)=171 ± 10, Mass (kg)= 74.60 ± 14.19), Beef (m=5, f=5; Age (yrs)=22 ± 4, Height (cm)=170 ± 7, Mass (kg)=70.13 ± 8.16), ChxC(m=5, f=6; Age (yrs)=21 ± 2, Height (cm)=169 ± 9, Mass (kg)=74...
April 7, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28399005/effects-of-a-6-month-caloric-restriction-induced-weight-loss-program-in-obese-postmenopausal-women-with-and-without-the-metabolic-syndrome-a-monet-study
#10
Ahmed Ghachem, Denis Prud'homme, Rémi Rabasa-Lhoret, Martin Brochu
OBJECTIVE: To compare the effects of a caloric restriction (CR) on body composition, lipid profile, and glucose homeostasis in obese postmenopausal women with and without metabolic syndrome (MetS). METHODS: Secondary analyses were performed on 73 inactive obese postmenopausal women (age 57.7 ± 4.8 years; body mass index 32.4 ± 4.6 kg/m) who participated in the 6-month CR arm of a study of the Montreal-Ottawa New Emerging Team. The harmonized MetS definition was used to categorize participants with MetS (n = 20, 27...
April 10, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28398475/fat-mass-and-obesity-associated-fto-protein-regulates-adult-neurogenesis
#11
Liping Li, Liqun Zang, Feiran Zhang, Junchen Chen, Hui Shen, Liqi Shu, Feng Liang, Chunyue Feng, Deng Chen, Huikang Tao, Tianlei Xu, Ziyi Li, Yunhee Kang, Hao Wu, Lichun Tang, Pumin Zhang, Peng Jin, Qiang Shu, Xuekun Li
Fat mass and obesity-associated gene (FTO) is a member of the Fe (II)- and oxoglutarate-dependent AlkB dioxygenase family and is linked to both obesity and intellectual disability. The role of FTO in neurodevelopment and neurogenesis, however, remains largely unknown. Here we show that FTO is expressed in adult neural stem cells and neurons and displays dynamic expression during postnatal neurodevelopment. The loss of FTO leads to decreased brain size and body weight. We find that FTO deficiency could reduce the proliferation and neuronal differentiation of adult neural stem cells in vivo, which leads to impaired learning and memory...
April 7, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28396303/effect-of-a-nine-month-web-and-app-based-workplace-intervention-to-promote-healthy-lifestyle-and-weight-loss-for-employees-in-the-social-welfare-and-health-care-sector-a-randomized-controlled-trial
#12
Nina Charlotte Balk-Møller, Sanne Kellebjerg Poulsen, Thomas Meinert Larsen
BACKGROUND: General health promoting campaigns are often not targeted at the people who need them the most. Web- and app-based tools are a new way to reach, motivate, and help people with poor health status. OBJECTIVE: The aim of our study was to test a Web- and mobile app-based tool ("SoSu-life") on employees in the social welfare and health care sector in Denmark. METHODS: A randomized controlled trial was carried out as a workplace intervention...
April 10, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28394825/body-composition-assessment-in-the-prediction-of-osteoporotic-fractures
#13
Mélany Hars, Andrea Trombetti
PURPOSE OF REVIEW: To give an overview of recent research findings and insights on the role of body composition assessment in fracture risk prediction. RECENT FINDINGS: While there is to date little doubt that bone mineral density (BMD) is a main pathogenic factor of osteoporotic fractures, recent studies have emphasized the independent contribution of body composition components, especially lean mass, to fracture risk. In this article, we address body composition changes with aging, before to focus on recent studies addressing the contribution of lean and fat mass to fracture risk, together with some hypothesized mechanisms and clinical implications...
April 7, 2017: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/28394176/physical-and-chemical-properties-of-meat-from-scavenging-chickens-and-helmeted-guinea-fowls-in-response-to-age-and-sex
#14
M T Musundire, T E Halimani, M Chimonyo
1. The effects of age and sex on body weight, carcass traits, physical and chemical properties of breast muscle from chickens and helmeted guinea fowls managed under village free range conditions, were assessed in random sample of 48 guinea fowls and 48 chickens obtained from local markets. 2. Guinea fowls had higher body weight, hot carcass weight, cold dressed weight and breast weight than chickens. 3. Guinea fowls had more dry matter, protein and less fat than chickens. Ash content did not differ between guinea fowls and chickens...
April 10, 2017: British Poultry Science
https://www.readbyqxmd.com/read/28392165/high-fat-mass-associates-with-occurrence-of-targeted-therapy-induced-left-ventricular-ejection-fraction-reduction-in-patients-with-renal-cell-carcinoma
#15
Seyyed Mohammad Reza Kazemi-Bajestani, Harald Becher, Peter Venner, Scott North, Vickie Baracos
BACKGROUND & AIMS: Recent research suggests that variations of skeletal muscle (SM) and fat predict the severity of chemotherapy-induced toxicities in patients with renal cell carcinoma (RCC). Cardio-toxicity has not been evaluated in this context. METHODS: In this study we considered 47 RCC patients who participated in randomized clinical trials of sorafenib or sunitinib (i.e., targeted therapy). To capture cardio-toxicity, multi gated acquisition (MUGA) scan-defined left ventricular ejection fraction (LVEF) tests (at least 3 tests over 1 year of treatment) were abstracted...
March 28, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28390870/insulin-not-glutamine-dipeptide-reduces-lipases-expression-and-prevents-fat-wasting-and-weight-loss-in-walker-256-tumor-bearing-rats
#16
Hely de Morais, Flaviane de Fatima Silva, Francemilson Goulart da Silva, Milene Ortiz Silva, Maria Fernanda Rodrigues Graciano, Maria Isabel Lovo Martins, Ângelo Rafael Carpinelli, Tânia Longo Mazucco, Roberto Barbosa Bazotte, Helenir Medri de Souza
Cachexia is the main cause of mortality in advanced cancer patients. We investigated the effects of insulin (INS) and glutamine dipeptide (GDP), isolated or associated, on cachexia and metabolic changes induced by Walker 256 tumor in rats. INS (NPH, 40 UI/kg, sc) or GDP (1.5g/kg, oral gavage) was once-daily administered during 11 days after tumor cell inoculation. GDP, INS or INS+GDP treatments did not influence the tumor growth. However, INS and INS+GDP prevented retroperitoneal fat wasting and body weight loss of tumor-bearing rats...
April 6, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28389409/anti-obesity-effect-of-a-novel-caffeine-loaded-dissolving-microneedle-patch-in-high-fat-diet-induced-obese-c57bl-6j-mice
#17
Manita Dangol, Suyong Kim, Cheng Guo Li, Shayan Fakhraei Lahiji, Mingyu Jang, Yonghao Ma, Inyoung Huh, Hyungil Jung
Natural products such as caffeine have been found to be effective in reducing body weight through lipolysis. Here, we report the successful loading of caffeine onto dissolving microneedle following inhibition of its crystal growth by hyaluronic acid (HA), the matrix material of the dissolving microneedle (DMN). Further, the anti-obesity activity of caffeine was evaluated in high-fat diet-induced obese C57BL/6J mice. After 6weeks of caffeine loaded dissolving microneedle patch (CMP) administration, lipolysis improved significantly as shown by leptin and adiponectin activity, which resulted in considerable weight loss of about 12...
April 4, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28388294/a-randomized-double-blind-placebo-controlled-trial-to-determine-the-effectiveness-and-safety-of-a-thermogenic-supplement-in-addition-to-an-energy-restricted-diet-in-apparently-healthy-females
#18
Kristina L Kendall, Parker N Hyde, Ciaran M Fairman, Kaitlyn M Hollaway, Petey W Mumford, Cody T Haun, Brooks Mobley, Wesley C Kephart, Aaron C Tribby, Dylan Kimber, Jordan R Moon, Darren T Beck, Michael D Roberts, Kaelin C Young
The increasing interest in weight loss has seen a concurrent rise in the supplemental use of thermogenics to aid weight loss efforts. To date, the effectiveness and safety of supplemental proprietary blend thermogenics, in conjunction with high-protein energy-restricted diets have not been thoroughly evaluated. The purpose of this study was to investigate the efficacy of a low-calorie, high-protein diet with and without the concomitant use of a thermogenic supplement on body weight and body composition in apparently healthy females...
April 7, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28387575/nutritional-considerations-for-bouldering
#19
Edward J Smith, Ryan Storey, Mayur K Ranchordas
Bouldering competitions are held up to International level and governed by the International Federation of Sport Climbing. Bouldering has been selected to feature at the 2020 Olympic Games in Tokyo, however, physiological qualities and nutritional requirements to optimise performance remain inadequately defined due to large gaps in the literature. The primary goals of training include optimising the capacity of the anaerobic energy systems and developing sport-specific strength, with emphasis on the isometric function of the forearm flexors responsible for grip...
April 7, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/28386755/rygb-produces-more-sustained-body-weight-loss-and-improvement-of-glycemic-control-compared-with-vsg-in-the-diet-induced-obese-mouse-model
#20
Zheng Hao, R Leigh Townsend, Michael B Mumphrey, Christopher D Morrison, Heike Münzberg, Hans-Rudolf Berthoud
BACKGROUND: Weight regain and type-2 diabetes relapse has been reported in a significant proportion of vertical sleeve gastrectomy (VSG) patients in some studies, but definitive conclusions regarding the long-term comparative effectiveness of VSG and Roux-en-Y gastric bypass (RYGB) surgery are lacking both in humans and rodent models. This study's objective was to compare the effects of murine models of VSG and RYGB surgery on body weight, body composition, food intake, energy expenditure, and glycemic control...
April 6, 2017: Obesity Surgery
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