keyword
MENU ▼
Read by QxMD icon Read
search

Body fat loss

keyword
https://www.readbyqxmd.com/read/28712591/normalizing-ovulation-rate-by-preferential-reduction-of-hepato-visceral-fat-in-adolescent-girls-with-polycystic-ovary-syndrome
#1
Lourdes Ibáñez, Luis Del Río, Marta Díaz, Giorgia Sebastiani, Óscar J Pozo, Abel López-Bermejo, Francis de Zegher
PURPOSE: Polycystic ovary syndrome (PCOS) is an increasingly prevalent disorder in adolescent girls, commonly presenting with hirsutism/oligomenorrhea, commonly treated with an oral contraceptive (OC), and commonly followed by oligoanovulatory subfertility. We tested whether an intervention targeting the reduction of hepato-visceral adiposity is followed by a higher ovulation rate than OC treatment. METHODS: This randomized, open-label, single-center, pilot proof-of-concept study (12 months on treatment, then 12 months off) was performed in adolescent girls with hirsutism and oligomenorrhea (PCOS by National Institutes of Health; no sexual activity; N = 36; mean age 16 years, body mass index 23...
July 13, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28710347/effects-of-lipoic-acid-on-high-fat-diet-induced-alteration-of-synaptic-plasticity-and-brain-glucose-metabolism-a-pet-ct-and-13-c-nmr-study
#2
Zhigang Liu, Ishan Patil, Harsh Sancheti, Fei Yin, Enrique Cadenas
High-fat diet (HFD)-induced obesity is accompanied by insulin resistance and compromised brain synaptic plasticity through the impairment of insulin-sensitive pathways regulating neuronal survival, learning, and memory. Lipoic acid is known to modulate the redox status of the cell and has insulin mimetic effects. This study was aimed at determining the effects of dietary administration of lipoic acid on a HFD-induced obesity model in terms of (a) insulin signaling, (b) brain glucose uptake and neuronal- and astrocytic metabolism, and (c) synaptic plasticity...
July 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28704610/effects-of-medium-and-long-chain-triacylglycerols-on-lipid-metabolism-and-gut-microbiota-composition-in-c57bl-6j-mice
#3
Shengmin Zhou, Yueqiang Wang, Jörg Jacoby, Yuanrong Jiang, Yaqiong Zhang, Liangli Lucy Yu
Obesity is related to an increasing risk of chronic diseases. Medium- and long-chain triacylglycerols (MLCT) have been recognized as a promising choice to reduce body weight. In this study, three MLCT with different contents of medium-chain fatty acids (MCFA) (10%-30%, w/w) were prepared, and their effects on lipid metabolism and fecal gut microbiota composition of C57BL/6J mice were systematically investigated. MLCT with 30% (w/w) MCFA showed the best performance in decreasing body weight gain as well as optimizing serum lipid parameters and liver triacylglycerol content...
July 13, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28702888/cushing-s-syndrome-a-model-for-sarcopenic-obesity
#4
Michael Drey, Christina M Berr, Martin Reincke, Julia Fazel, Jochen Seissler, Jochen Schopohl, Martin Bidlingmaier, Stefanie Zopp, Nicole Reisch, Felix Beuschlein, Andrea Osswald, Ralf Schmidmaier
PURPOSE: Obesity and its metabolic impairments are discussed as major risk factors for sarcopenia leading to sarcopenic obesity. Cushing's syndrome is known to be associated with obesity and muscle atrophy. We compared Cushing's syndrome with matched obese controls regarding body composition, physical performance, and biochemical markers to test the hypothesis that Cushing's syndrome could be a model for sarcopenic obesity. METHODS: By propensity score matching, 47 controls were selected by body mass index and gender as obese controls...
July 12, 2017: Endocrine
https://www.readbyqxmd.com/read/28700832/a-12-week-low-carbohydrate-high-fat-lchf-diet-improves-metabolic-health-outcomes-over-a-control-diet-in-a-randomised-controlled-trial-with-overweight-defence-force-personnel
#5
Caryn Zinn, Julia McPhee, Nigel Kent Harris, Micalla Williden, Kate Prendergast, Grant Schofield
INTRODUCTION: Overweight, obesity and poor health is becoming a global concern for defence force personnel. Conventional nutrition guidelines are being questioned for their efficacy in achieving optimal body composition and long-term health. This study compared the effects of a 12-week low-carbohydrate, high-fat diet with a conventional, high-carbohydrate, low-fat diet on weight reduction and metabolic health outcomes in at-risk New Zealand Defence Force personnel. MATERIALS AND METHODS: In this randomised controlled trial, 41 overweight personnel were assigned to intervention and control groups...
July 12, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28700645/overweight-in-young-males-reduce-fertility-in-rabbit-model
#6
Francisco Marco-Jiménez, José Salvador Vicente
Semen quality has certainly declined over the past few decades, possibly owing to modern lifestyle factors. In this sense, the role of overweight and obesity in the development of subfertility in males has generated a considerable amount of interest in recent years. However, there is no consensus on whether overweight or obesity impaired sperm quality. Thus, based on the ongoing debate about risk factors for subfertility associated with overweight and obesity in men, this study was designed to investigate the effect of overweight on sperm quality parameters and fertility success in randomized controlled trial in a rabbit model...
2017: PloS One
https://www.readbyqxmd.com/read/28694840/hepatic-adipocyte-enteric-and-pancreatic-hormones-response-to-dietary-macronutrient-composition-and-relationship-with-metabolism
#7
Bridget M Hron, Cara B Ebbeling, Henry A Feldman, David S Ludwig
BACKGROUND: We sought to characterize the effects of dietary macronutrient composition on various hormones implicated in the regulation of insulin sensitivity (IS) and energy expenditure (EE). METHODS: Following 10-15% weight loss, 21 overweight subjects consumed 3 weight-loss maintenance diets [low fat (LF), low glycemic index (LGI) and very low carbohydrate (VLC)] in random order, each for 4 weeks. At baseline and at the end of each treatment period, fasting samples for fibroblast growth factor (FGF)-21, heme-oxygenase-1 (HO-1), chemerin, irisin, secreted frizzle-related protein (SFRP-4), total bile acids, ghrelin, gastrin inhibitory peptide (GIP), peptide-Y, and amylin; hepatic and peripheral IS; and EE were obtained...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/28694154/short-photoperiod-reverses-obesity-in-siberian-hamsters-via-sympathetically-induced-lipolysis-and-browning-in-adipose-tissue
#8
REVIEW
Vitaly Ryu, Eleen Zarebidaki, H Elliott Albers, Bingzhong Xue, Timothy J Bartness
Changes in photoperiod length are transduced into neuroendocrine signals by melatonin (MEL) secreted by the pineal gland triggering seasonally adaptive responses in many animal species. Siberian hamsters, transferred from a long-day 'summer-like' photoperiod (LD) to a short-day 'winter-like' photoperiod (SD), exhibit a naturally-occurring reversal in obesity. Photoperiod-induced changes in adiposity are mediated by the duration of MEL secretion and can be mimicked by exogenously administered MEL into animals housed in LD...
July 7, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28692020/comparative-effectiveness-of-a-portion-controlled-meal-replacement-program-for-weight-loss-in-adults-with-and-without-diabetes-high-blood-sugar
#9
C D Coleman, J R Kiel, A H Mitola, L M Arterburn
BACKGROUND: Individuals with type 2 diabetes (DM2) may be less successful at achieving therapeutic weight loss than their counterparts without diabetes. This study compares weight loss in a cohort of adults with DM2 or high blood sugar (D/HBS) to a cohort of adults without D/HBS. All were overweight/obese and following a reduced or low-calorie commercial weight-loss program incorporating meal replacements (MRs) and one-on-one behavioral support. SUBJECTS/METHODS: Demographic, weight, body composition, anthropometric, pulse and blood pressure data were collected as part of systematic retrospective chart review studies...
July 10, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28689248/daily-self-weighing-and-weight-gain-prevention-a-longitudinal-study-of-college-aged-women
#10
Diane L Rosenbaum, Hallie M Espel, Meghan L Butryn, Fengqing Zhang, Michael R Lowe
Daily self-weighing has been suggested as an important factor for weight loss maintenance among samples with obesity. This study is a secondary analysis that examined daily self-weighing in association with weight and body composition outcomes over 2 years among young women with vulnerability for weight gain. Women (N = 294) of varying weight status completed self-weighing frequency questionnaires and weight was measured in the clinic at baseline, 6 months, 1, and 2 years; DXA scans were completed at baseline, 6 months and 2 years...
July 8, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28687371/body-weight-loss-effective-satiation-and-absence-of-homeostatic-neuropeptide-compensation-in-male-sprague-dawley-rats-schedule-fed%C3%A2-a-protein-crosslinked-diet
#11
Nikki Cassie, Richard L Anderson, Dana Wilson, Anne Pawsey, Julian G Mercer, Perry Barrett
Food structure contributes to the induction of satiation and the maintenance of satiety following intake of a meal. There is evidence from human studies that protein-crosslinking of a milk-protein based meal may enhance satiety, but the mechanism underpinning this effect is unknown. We investigated whether a rat model would respond in a similar manner and might provide mechanistic insight into enhanced satiety by structural modification of a food source. Rats were schedule fed a modified AIN-93M based diet in a liquid form or protein-crosslinked to produce a soft-solid form...
July 5, 2017: Appetite
https://www.readbyqxmd.com/read/28685361/bariatric-surgery-promising-in-migraine-control-a-controlled-trial-on-weight-loss-and-its-effect-on-migraine-headache
#12
Soodeh Razeghi Jahromi, Maryam Abolhasani, Zeinab Ghorbani, Solmaz Sadre-Jahani, Zahra Alizadeh, Mohammad Talebpour, Alipasha Meysamie, Mansoureh Togha
INTRODUCTION: There is evidence that substantial weight loss through bariatric surgery (BS) may result in short-term improvement of migraine severity. However, it still remains to be seen whether smaller amounts of weight loss have a similar effect on migraine headache. This study has been designed to compare the effects of weight reduction through BS and non-surgical modifications. MATERIALS AND METHODS: Migraine characteristics were assessed at 1 month before (T0), 1 month (T1), and 6 months (T2) after BS (vertical sleeve gastrectomy (VSG) (n = 25) or behavioral therapy (BT) (n = 26) in obese women (aged 18-60 years) with migraine headache...
July 6, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28684917/effects-of-a-tailored-lifestyle-self-management-intervention-talent-study-on-weight-reduction-a-randomized-controlled-trial
#13
Dieter Melchart, Peter Löw, Erich Wühr, Victoria Kehl, Wolfgang Weidenhammer
OBJECTIVE: Overweight and obesity are globally increasing risk factors for diseases in the context of metabolic syndrome. A randomized controlled trial was conducted to investigate whether there are any existing differences between two lifestyle intervention strategies with respect to weight reduction after 1 year. SUBJECTS AND METHODS: A total of 166 subjects with a body mass index of 28-35 kg/m(2) were enrolled in this trial at seven study centers; 109 were randomly allocated to the intervention group (comprehensive lifestyle modification program: web-based Individual Health Management [IHM]) with 3-month reduction phase plus 9-month maintenance phase, and 57 were allocated to the control group (written information with advice for healthy food habits: usual care [UC])...
2017: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
https://www.readbyqxmd.com/read/28684685/factors-associated-with-bone-health-in-malaysian-middle-aged-and-elderly-women-assessed-via-quantitative-ultrasound
#14
Kok-Yong Chin, Nie Yen Low, Wan Ilma Dewiputri, Soelaiman Ima-Nirwanaa
Risk factors for osteoporosis may vary according to different populations. We aimed to investigate the relationship between risk factors of osteoporosis and bone health indices determined via calcaneal quantitative ultrasound (QUS) in a group of Malaysian women aged 50 years or above. A cross-sectional study was performed on 344 Malaysian women recruited from a tertiary medical centre in Kuala Lumpur, Malaysia. They answered a self-administered questionnaire on their social-demographic details, medical history, lifestyle, and physical activity status...
July 6, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28679946/independent-tissue-contributors-to-obesity-associated-insulin-resistance
#15
Yvo Ham Kusters, Casper G Schalkwijk, Alfons Jhm Houben, M Eline Kooi, Lucas Lindeboom, Jos Op 't Roodt, Peter J Joris, Jogchum Plat, Ronald P Mensink, Eugene J Barrett, Coen DA Stehouwer
BACKGROUND: Induction of insulin resistance is a key pathway through which obesity increases risk of type 2 diabetes, hypertension, dyslipidemia, and cardiovascular events. Although the detrimental effects of obesity on insulin sensitivity are incompletely understood, accumulation of visceral, subcutaneous, and liver fat and impairment of insulin-induced muscle microvascular recruitment (MVR) may be involved. As these phenotypic changes often coincide in obesity, we aimed to unravel whether they independently contribute to insulin resistance and thus constitute separate targets for intervention...
July 6, 2017: JCI Insight
https://www.readbyqxmd.com/read/28679554/protein-supplements-after-weight-loss-do-not-improve-weight-maintenance-compared-with-recommended-dietary-protein-intake-despite-beneficial-effects-on-appetite-sensation-and-energy-expenditure-a-randomized-controlled-double-blinded-trial
#16
Louise Kjølbæk, Lone Brinkmann Sørensen, Nadja Buus Søndertoft, Carrie Klestrup Rasmussen, Janne Kunchel Lorenzen, Anja Serena, Arne Astrup, Lesli Hingstrup Larsen
Background: High-protein diets increase weight loss (WL) during energy restriction; therefore, it has been suggested that additional protein intake may improve weight maintenance (WM) after WL.Objective: We investigated the effect of protein supplements from either whey with or without calcium or soy on WM success after WL compared with that of a control.Design: In a randomized, controlled, double-blinded trial, 220 participants aged 18-60 y with body mass index (in kg/m(2)) from 27.6 to 40.4 were included...
July 5, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28678735/browning-formation-markers-of-subcutaneous-adipose-tissue-in-relation-to-resting-energy-expenditure-physical-activity-and-diet-in-humans
#17
Petros C Dinas, Angelica Valente, Marnie Granzotto, Marco Rossato, Roberto Vettor, Aikaterini Zacharopoulou, Andres E Carrillo, Natalie A Davies, Paraskevi Gkiata, Athanasios Z Jamurtas, Yiannis Koutedakis, George S Metsios, Andreas D Flouris
Background Regular exercise and diet may contribute to white adipose tissue (WAT) conversion into a brown adipose-like phenotype that may increase resting energy expenditure (REE), leading to weight loss. We examined the relationship between REE, physical activity (PA) participation and diet with browning formation markers of subcutaneous WAT in healthy men. Materials and methods We assessed REE, diet and body composition of 32 healthy men [age (years): 36.06 ± 7.36, body mass index (BMI): 27.06 ± 4.62 (kg/m2)]...
July 5, 2017: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/28678523/nutritional-biomarkers-current-view-and-future-perspectives
#18
Shubhra Pande, Valentina A Kratasyuk, Nadezhda N Medvedeva, Oxana A Kolenchukova, Alla B Salmina
There is a poor relationship between nutrient intake and existing nutritional biomarkers due to variety of factors affecting their sensitivity and specificity. To explore the impact of nutrients at molecular level and devising a sensitive biomarker, proteomics is a central technology with sirtuins as one of the most promising nutritional biomarker. Sirtuins (seven mammalian sirtuins reported so far), have been reported to perform protein deacetylases and ADP-ribosyltransferases activity. It is distributed in different cellular compartments thereby controlling several metabolic processes...
July 5, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28677502/pten-insulin-resistance-and-cancer
#19
Aiqing Li, Minzi Qiu, Hongbo Zhou, Tao Wang, Wen Guo
BACKGROUND: The tumor suppressor PTEN serves as a negative regulator of PI3K/PTEN/Akt signaling pathway that regulates cellular functions such as cell growth, differentiation, proliferation and migration. The PI3K/PTEN/Akt signaling cascades might also have effect on glucose uptake via translocation of GLUT-4. Insulin controls energy storage and the whole body glucose homeostasis. Its binding to insulin receptor on the surface of diverse cells allows glucose entry into cells, and activates a variety of cellular actions...
July 4, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28670535/effect-of-antithyroid-therapies-on-bone-and-body-composition-a-prospective-randomized-clinical-study-comparing-antithyroid-drugs-with-radioiodine-therapy
#20
Shekhar Kansara, Narendra Kotwal, K V S Hari Kumar, Yashpal Singh, Vimal Upreti, Amit Nachankar
BACKGROUND: Thyrotoxicosis is associated with loss of body weight and bone mineral content (BMC). Antithyroid drugs (ATD) and radioiodine therapy (RIT) are the common options for the management of thyrotoxicosis. We evaluated the effect of ATD and RIT on BMC and body composition. MATERIALS AND METHODS: In this prospective study, we randomized 60 patients of thyrotoxicosis (20-50 years, treatment naïve, males) to receive either ATD (Group 1) using carbimazole or RIT (Group 2)...
July 2017: Indian Journal of Endocrinology and Metabolism
keyword
keyword
61820
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"