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https://www.readbyqxmd.com/read/28103619/pregnant-women-in-sport-climbing-is-there-a-higher-risk-for-preterm-birth
#1
Jan Drastig, David Hillebrandt, Werner Rath, Thomas Küpper
Sport climbing is a popular recreational sport with an increasing proportion of female athletes. International recommendations emphasize the physical and mental benefits of regular sport activity during any uncomplicated pregnancy. In this context, sport climbing is associated with a high risk potential.The aim of this study was to examine if there is a higher risk for preterm birth in active climbing athletes.Original manuscript.A retrospective self-report online survey in the German language collected data between September 2012 and November 2013...
January 19, 2017: Zeitschrift Für Geburtshilfe und Neonatologie
https://www.readbyqxmd.com/read/28096447/pbp1b-glycosyltransferase-and-transpeptidase-activities-play-different-essential-roles-during-the-de-novo-regeneration-of-rod-shaped-morphology-in-escherichia-coli
#2
Dev K Ranjit, Matthew A Jorgenson, Kevin D Young
: Peptidoglycan is a vital component of nearly all cell wall-bearing bacteria and is a valuable target for antibacterial therapy. However, despite decades of work, there remain important gaps in understanding how this macromolecule is synthesized and molded into a three-dimensional structure that imparts specific morphologies to individual cells. Here, we investigate the particularly enigmatic area of how peptidoglycan is synthesized and shaped during the first stages of creating cell shape de novo, that is, in the absence of a pre-existing template...
January 17, 2017: Journal of Bacteriology
https://www.readbyqxmd.com/read/28068480/magnetic-resonance-imaging-characterization-and-clinical-outcomes-after-neocart-surgical-therapy-as-a-primary-reparative-treatment-for-knee-cartilage-injuries
#3
Devon E Anderson, Riley J Williams, Thomas M DeBerardino, Dean C Taylor, C Benjamin Ma, Marie S Kane, Dennis C Crawford
BACKGROUND: Autologous cartilage tissue implants, including the NeoCart implant, are intended to repair focal articular cartilage lesions. Short-term results from United States Food and Drug Administration (FDA) phase I and phase II clinical trials indicated that the NeoCart implant was safe when surgically applied as a cell-based therapy and efficacious compared with microfracture. HYPOTHESIS: Quantitative magnetic resonance imaging (MRI) analysis would reveal NeoCart tissue maturation through to 60-month follow-up...
January 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28042751/lateral-foot-pain-in-a-recreational-runner
#4
Brian A Young, Joshua R Kniss, Felix Islas
A 35-year-old male recreational runner with a 9-month history of left lateral foot pain self-referred to physical therapy while awaiting orthopaedic consultation. Before presenting to physical therapy, his primary care physician ordered radiographs and referred him to orthopaedics with a provisional diagnosis of multipartite os peroneum. Following examination, the initial treatment hypothesis was cuboid syndrome, as he met the majority of items in a proposed diagnostic cluster. J Orthop Sports Phys Ther 2017;47(1):41...
January 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28017184/patient-reported-pathways-to-opioid-use-disorders-and-pain-related-barriers-to-treatment-engagement
#5
Scott P Stumbo, Bobbi Jo H Yarborough, Dennis McCarty, Constance Weisner, Carla A Green
BACKGROUND: Risk factors associated with developing opioid use disorders (OUD) are documented, but less is known about different pathways to initiation of opioids or opioid dependence, or how such pathways affect treatment engagement. METHODS: We recruited 283 adults with electronic medical record (EMR) evidence of opioid dependence diagnoses. Open-ended and structured interview items focused on prior opioid treatment experiences, barriers to and knowledge of treatment options...
February 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28012121/triathlon-training-for-women-breast-cancer-survivors-feasibility-and-initial-efficacy
#6
Alexander V Ng, Alyson N Cybulski, Ashley A Engel, Paula E Papanek, Megan A Sheffer, Leslie J Waltke, Judy A Tjoe
: ᅟ: Exercise can improve quality of life (QOL) in breast cancer survivors. In contrast to many group or home-based exercise programs, little is known about the effectiveness of goal-oriented recreational activities. PURPOSE: The purpose of this study was to evaluate a clinically overseen team triathlon training program on improving physiological and psychosocial health-related measures in female breast cancer survivors. METHODS: Twenty-three participants (age = 48 (8), BMI = 25 (1), mean (SE)) were recruited from a 14-week sprint triathlon (800-m swim, 20-km bike, 5-km run) team training program for women breast cancer survivors (4 (3) years post-surgery, chemo-, or radiation-therapy)...
December 24, 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28009676/effectiveness-of-meaningful-occupation-interventions-for-people-living-with-dementia-in-residential-aged-care-a-systematic-review
#7
Catherine Travers, Deborah Brooks, Sonia Hines, Maria O'Reilly, Mitchell McMaster, Wei He, Margaret MacAndrew, Elaine Fielding, Lina Karlsson, Elizabeth Beattie
BACKGROUND: The ability to participate in valued activities, whether for work, leisure or family, is an important aspect of personal identity. In dementia, progressive memory loss means that abilities developed over a lifetime begin to be lost as well, contributing to the loss of self and identity. Some studies have reported that activities or interventions tailored to be meaningful to the person with dementia (defined as any activity important to the individual) are more effective in addressing behavioral and psychological symptoms of dementia (BPSD) and improving quality of life (QoL) than those that are not so tailored...
December 2016: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/27993588/effect-of-a-single-administration-of-focused-extracorporeal-shock-wave-in-the-relief-of-delayed-onset-muscle-soreness-results-of-a-partially-blinded-randomized-controlled-trial
#8
Johannes Fleckenstein, Mara Friton, Heiko Himmelreich, Winfried Banzer
OBJECTIVES: To examine the effects of a single administration of focused extracorporeal shockwave therapy (fESWT) on eccentric exercise-induced delayed-onset muscle soreness (DOMS). DOMS is a common symptom in people participating in exercise, sports, or recreational physical activities. DESIGN: Three-arm randomized controlled study conducted in 2009. SETTING: DOMS was induced by eccentric exercise of the non-dominant arm in voluntary participants at the Sports Campus of a German university...
December 16, 2016: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/27990301/robotic-seals-as-therapeutic-tools-in-an-aged-care-facility-a-qualitative-study
#9
Melanie Birks, Marie Bodak, Joanna Barlas, June Harwood, Mary Pether
Robots, including robotic seals, have been used as an alternative to therapies such as animal assisted therapy in the promotion of health and social wellbeing of older people in aged care facilities. There is limited research available that evaluates the effectiveness of robot therapies in these settings. The aim of this study was to identify, explore, and describe the impact of the use of Paro robotic seals in an aged care facility in a regional Australian city. A qualitative, descriptive, exploratory design was employed...
2016: Journal of Aging Research
https://www.readbyqxmd.com/read/27960233/iatrogenic-changes-in-the-urinary-tract
#10
REVIEW
Antonio Lopez-Beltran, Gladell P Paner, Rodolfo Montironi, Maria R Raspollini, Liang Cheng
A handful of therapeutic procedures are used to treat malignancies of the urinary tract, most frequently intravesical immunotherapy or chemotherapy, but also neoadjuvant systemic chemotherapy. These treatment modalities produce morphological changes in the urothelium that can be mistaken for carcinoma; in particular, these therapies frequently mimic urothelial carcinoma in situ (CIS) urothelial dysplasia or true invasive neoplasia. Drugs such as mitomycin C used after transurethral resection of bladder tumour to reduce recurrences, bacillus Calmette-Guérin (BCG) intravesical immunotherapy to treat high-risk non-muscle-invasive bladder cancer and urothelial CIS and platin-based systemic chemotherapy to improve postcystectomy disease-specific survival are examples of therapy-related atypia seen in the urinary tract...
January 2017: Histopathology
https://www.readbyqxmd.com/read/27940379/native-thymic-extracellular-matrix-improves-in%C3%A2-vivo-thymic-organoid-t-cell-output-and-drives-in%C3%A2-vitro-thymic-epithelial-cell-differentiation
#11
Michael Hun, Marco Barsanti, Kahlia Wong, John Ramshaw, Jerome Werkmeister, Ann P Chidgey
Although the thymus is a primary lymphoid organ, its function is compromised by an age-induced loss of resident epithelial cells, which results in reduced naïve T cell output. This has important implications for immune recovery in aged and elderly patients following damage from cytoablative therapies. As thymic architecture plays a crucial role in naïve T cell development, a tissue specific scaffold that provides essential supporting matrix may assist in stem cell-based thymus regeneration to recreate complex organoids...
February 2017: Biomaterials
https://www.readbyqxmd.com/read/27918210/emerging-therapeutic-interventions-against-noise-induced-hearing-loss
#12
Su-Hua Sha, Jochen Schacht
Noise-induced hearing loss (NIHL) due to industrial, military, and recreational noise exposure is a major, but also potentially preventable cause of acquired hearing loss. For the United States it is estimated that 26 million people (15% of the population) between the ages of 20 and 69 have a high-frequency NIHL at a detriment to the quality of life of the affected individuals and great economic cost to society. Areas covered: This review outlines the pathology and pathophysiology of hearing loss as seen in humans and animal models...
January 2017: Expert Opinion on Investigational Drugs
https://www.readbyqxmd.com/read/27912994/deconstructing-postmastectomy-syndrome-implications-for-physiatric-management
#13
REVIEW
Eric Wisotzky, Nicole Hanrahan, Thomas P Lione, Susan Maltser
Postmastectomy pain syndrome is a common sequela of breast cancer treatment that can lead to impairments and limited participation in work, recreational, and family roles. Pain can originate from multiple anatomic sites. A detailed evaluation to determine the specific cause or causes of pain will help guide the clinician to successfully manage this pain syndrome. There are many available treatments, but more evidence is needed for the efficacy of rehabilitation, pharmacologic, and nonpharmacologic therapy. There is evidence for some effective treatments to prevent this syndrome, but, here also, more research is needed...
February 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/27910972/a-liver-microphysiological-system-of-tumor-cell-dormancy-and-inflammatory-responsiveness-is-affected-by-scaffold-properties
#14
A M Clark, S E Wheeler, C L Young, L Stockdale, J Shepard Neiman, W Zhao, D B Stolz, R Venkataramanan, D Lauffenburger, L Griffith, A Wells
Distant metastasis is the major cause of breast cancer-related mortality, commonly emerging clinically after 5 or more years of seeming 'cure' of the primary tumor, indicating a quiescent dormancy. The lack of relevant accessible model systems for metastasis that recreate this latent stage has hindered our understanding of the molecular basis and the development of therapies against these lethal outgrowths. We previously reported on the development of an all-human 3D ex vivo hepatic microphysiological system that reproduces several features of liver physiology and enables spontaneous dormancy in a subpopulation of breast cancer cells...
December 20, 2016: Lab on a Chip
https://www.readbyqxmd.com/read/27907114/rates-and-predictors-of-non-adherence-to-antiretroviral-therapy-among-hiv-positive-individuals-in-kenya-results-from-the-second-kenya-aids-indicator-survey-2012
#15
Irene N Mukui, Lucy Ng'ang'a, John Williamson, Joyce N Wamicwe, Shobha Vakil, Abraham Katana, Andrea A Kim
INTRODUCTION: Understanding the levels and associated factors of non-adherence to antiretroviral therapy (ART) is crucial in designing interventions to improve adherence and health outcomes of ART. We assessed non-adherence to ART among HIV-infected persons reporting ART use in a nationally representative survey in Kenya. METHODS: The Kenya AIDS Indicator Survey 2012 was a population-based, household survey of persons aged 18 months-64 years conducted in 2012-2013...
2016: PloS One
https://www.readbyqxmd.com/read/27889374/-consumption-of-cannabis-in-adolescents
#16
O Phan, I Obradovic, A Har
Over the past 10 years, the consumption of cannabis among adolescents has dramatically increased. Today, adolescent cannabis use is a major public health problem. Two forms of cannabis are commonly smoked: herb (marijuana) and resin. These forms have a high concentration of tetrahydrocannabinol, the active molecule of cannabis. Recent research has helped understand how the cannabinoid system works. This system combines specific receptors and specific molecules: the endocannabinoids. The effects of cannabis use are now well documented...
January 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/27869581/physical-activity-in-ankylosing-spondylitis-evaluation-and-analysis-of-an-ehealth-tool
#17
Jess Shelagh Tyrrell, Clare Helen Redshaw
BACKGROUND: Ankylosing spondylitis (AS) is a chronic inflammatory condition characterised by spinal arthritis and exercise is often recommended to reduce the symptoms and improve mobility. However, very little evidence exists for the value of exercise in AS. OBJECTIVES: Firstly, this pilot study aimed to evaluate an eHealth tool, the AS Observer, specifically designed to monitor symptoms, quality of life and physical activity in AS, in terms of patient experience and suitability in generating data for epidemiological studies...
July 4, 2016: Journal of Innovation in Health Informatics
https://www.readbyqxmd.com/read/27849465/outcomes-associated-with-the-intrepid-dynamic-exoskeletal-orthosis-ideo-a-systematic-review-of-the-literature
#18
M Jason Highsmith, Leif M Nelson, Neil T Carbone, Tyler D Klenow, Jason T Kahle, Owen T Hill, Jason T Maikos, Mike S Kartel, Billie J Randolph
High-energy lower extremity trauma is a consequence of modern war and it is unclear if limb amputation or limb salvage enables greater recovery. To improve function in the injured extremity, a passive dynamic ankle-foot orthosis, the Intrepid Dynamic Exoskeletal Orthosis (IDEO), was introduced with specialized return to run (RTR) therapy program. Recent research suggests, these interventions may improve function and return to duty rates. This systematic literature review sought to rate available evidence and formulate empirical evidence statements (EESs), regarding outcomes associated with IDEO utilization...
November 2016: Military Medicine
https://www.readbyqxmd.com/read/27837497/the-changing-epidemiology-of-invasive-fungal-infections
#19
David A Enoch, Huina Yang, Sani H Aliyu, Christianne Micallef
Invasive fungal infections (IFI) are an emerging problem worldwide with invasive candidiasis and candidemia responsible for the majority of cases. This is predominantly driven by the widespread adoption of aggressive immunosuppressive therapy among certain patient populations (e.g., chemotherapy, transplants) and the increasing use of invasive devices such as central venous catheters (CVCs). The use of new immune modifying drugs has also opened up an entirely new spectrum of patients at risk of IFIs. While the epidemiology of candida infections has changed in the last decade, with a gradual shift from C...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27832579/screening-and-management-of-risk-factors-for-cardiovascular-disease-in-hiv-positive-patients-attending-an-australian-urban-sexual-health-clinic
#20
Sheena Kakar, Douglas Drak, Tahiya Amin, Jason Cheung, Catherine O'Connor, David Gracey
Background: Few data exist regarding cardiovascular risk among HIV-infected patients attending sexual health clinics (SHC) in Australia. Methods: The medical records of 188 patients attending an inner-city SHC between August 2013 and July 2014 were retrospectively reviewed for cardiovascular risk factors and associated screening and management practices. Results: Cardiovascular risk factors were common among attendees of the SHC, including smoking (38%), hypertension (14%) and dyslipidaemia (11%). Of the 188 patients, 23% reported using potentially cardiotoxic recreational drugs, 25% of dyslipidaemic patients were not on therapy and 10% of patients were hypertensive; none were prescribed treatment...
November 11, 2016: Sexual Health
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