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https://www.readbyqxmd.com/read/29332424/salivary-metabolomics-profile-of-patients-with-recurrent-aphthous-ulcer-as-revealed-by-liquid-chromatography-tandem-mass-spectrometry
#1
Yantao Li, Daoming Wang, Chunwei Zeng, Yichen Liu, Guangyuan Huang, Zhanlong Mei
Objective We compared the salivary nontargeted metabolite profiles between patients with recurrent aphthous ulcer (RAU) and healthy individuals to investigate the metabolic alterations associated with RAU. Methods Saliva samples were collected from 45 patients with RAU and 49 healthy individuals, and the salivary metabolites were quantified using liquid chromatography-tandem mass spectrometry. The metabolomic profiles were then analyzed using multivariate and univariate statistical methods, and enrichment of the metabolites in various biological pathways was assessed...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29327722/healthy-lifestyle-habits-benefit-remission-of-recurrent-aphthous-stomatitis-and-ras-type-ulceration
#2
L Ge
In a clinical setting, it is not practical to separate recurrent aphthous stomatitis (RAS) from RAS-type ulceration in every case, so both conditions have been considered together for the purpose of this article. Due to the lack of consistently effective therapeutic options for RAS, other approaches to treat the disease are considered here, beginning with an analysis of possible aetiological factors. The aetiology of RAS, the most common mucosal disease, remains undefined thus far. A few researchers have proposed psychological disorders as a major factor impacting RAS...
January 12, 2018: British Dental Journal
https://www.readbyqxmd.com/read/29296268/association-of-serotonin-transporter-gene-polymorphism-with-recurrent-aphthous-stomatitis
#3
Shamsolmolouk Najafi, Mahsa Mohammadzadeh, Amirabbas Zahedi, Mansour Heidari, Nima Rezaei
Background: Recurrent Aphthous Stomatitis (RAS) is one of the most common diseases of the oral cavity all over the world (5-66%). RAS has a multifactorial etiology, while psychological factors such as stress and anger play a role in its manifestation. The serotonergic mechanisms particularly the serotonin-transporter gene (5-HTT) may affect the risk of psychological alterations and stress response. The aim of the present study was to evaluate the polymorphism of the promoter region of 5-HTT (5-HTTLPR) in the patients with RAS, compared to that in the control subjects...
January 2018: Avicenna Journal of Medical Biotechnology
https://www.readbyqxmd.com/read/29287012/magnetic-resonance-enterography-cannot-replace-upper-endoscopy-in-pediatric-crohn-s-disease-an-imagekids-sub-study
#4
Peter C Church, Ruth Cytter Kuint, Oren Ledder, Victor M Navas-López, Malgorzata Sladek, Annecarin Brückner, Robert N Baldassano, Batia Weiss, Baruch Yerushalmi, Shehzad A Saeed, Jeffrey Hyams, Anthony Otley, Anne M Griffiths, Dan Turner, Mary-Louise C Greer
OBJECTIVES: While magnetic resonance enterography (MRE) can accurately reflect ileal inflammation in pediatric Crohn's disease (CD), there are no pediatric data on the accuracy of MRE to detect upper gastrointestinal tract (UGI) lesions. We aimed to compare MRE and esophagogastroduodenoscopy (EGD) in detecting the spectrum and severity of UGI disease in children. METHODS: This is an ancillary study of the prospective multi-center ImageKids study focusing on pediatric MRE...
December 28, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29284468/evaluation-of-the-content-quality-of-websites-for-recurrent-aphthous-ulcers-and-oral-lichen-planus
#5
Xiaosheng Hu, Hui Pan, Wenxiu He, Hong Hua, Zhimin Yan
BACKGROUND: The Internet is one of the most popular resources for people to obtain medical information; however, only a limited number of studies have reported the quality of the available health information related to oral mucosal diseases. The present study aimed to evaluate the quality of information on websites for recurrent aphthous ulcers (RAU) and oral lichen planus (OLP), in both Chinese and English. METHODS: Common search engines, BaiDu, Google, and Yahoo in Chinese; and Bing, Google, and Yahoo in English were used to identify websites providing content related to the oral mucosal diseases...
December 29, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/29279685/psychological-factors-in-oral-mucosal-and-orofacial-pain-conditions
#6
REVIEW
Mohammad S Alrashdan, Mustafa Alkhader
The psychological aspects of chronic pain conditions represent a key component of the pain experience, and orofacial pain conditions are not an exception. In this review, we highlight how psychological factors affect some common oral mucosal and orofacial pain conditions (namely, oral lichen planus, recurrent aphthous stomatitis, burning mouth syndrome, and temporomandibular disorders) with emphasis on the significance of supplementing classical biomedical treatment modalities with appropriate psychological counseling to improve treatment outcomes in targeted patients...
October 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/29278022/recurrent-aphthous-ulceration-a-review-of-potential-causes-and-novel-treatments
#7
Sami Kameel Saikaly, Tanya Siham Saikaly, Lara Elizabeth Saikaly
Purpose of Article: This review examines studies published between May 2012 and May 2017 with a specific interest in potential recurrent aphthous ulceration (RAU) etiologies and treatment modalities/efficacy, including topical treatments, systemic regimens, vitamin repletion, and laser therapy, among others. MATERIALS AND METHODS: PubMed MEDLINE and Cochrane Database of Systematic Reviews were searched using various combinations of: 'aphthous', 'ulcer', and 'treatment'. The titles and abstracts from the initial literature search were appraised to identify articles for full review, and reference sections from each article were searched manually for relevant publications...
December 26, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29259628/relative-efficacy-of-quercetin-compared-with-benzydamine-hydrochloride-in-minor-aphthae-a-prospective-parallel-double-blind-active-control-preliminary-study
#8
Maitreyi Pandya, Anupama N Kalappanavar, Rajeshwari G Annigeri, Dhanya S Rao
Background and Objectives: Recurrent aphthous stomatitis is an inflammatory condition present since ancient era wherein numerous treatment modalities have been tried. But complete eradication of the disease has not been possible and hence newer agents are being introduced. One such agent is a flavonoid named quercetin with proven antioxidant, anti-inflammatory, and ulcer healing properties. Methods: 40 patients with minor aphthous ulcers were divided equally into two groups: A and B...
2017: International Journal of Dentistry
https://www.readbyqxmd.com/read/29246466/the-first-international-conference-on-periodic-fever-aphthous-stomatitis-pharyngitis-adenitis-syndrome
#9
Liora Harel, Philip J Hashkes, Sivia Lapidus, Kathryn M Edwards, Shai Padeh, Marco Gattorno, Gary S Marshall
No abstract text is available yet for this article.
December 12, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29245339/ten-year-progress-of-coronary-artery-lesions-prior-to-beh%C3%A3-et-disease-diagnosis-a-case-report-and-care-compliant-article
#10
Wenfang Ma, Yan Liang, Jun Zhu
INTRODUCTION: Behçet disease is a multisystemic chronic inflammatory disorder characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions. However, particularly part of patients would present cardiovascular involvements and vascular lesions could be the presenting sign of Behçet disease preceding classical symptoms. We presented a middle aged male patient, in whom abdominal aorta pseudoaneurysm was as the first leading sign to reveal Behçet disease, and with his coronary artery lesions progress through a 10-year period before Behçet disease was diagnosed...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29241760/miscellaneous-skin-disease-and-the-metabolic-syndrome
#11
Sila Seremet, Mehmet Salih Gurel
The link between the metabolic syndrome (MetS) and skin diseases is increasingly important, with new associations being discovered. The association between MetS and psoriasis or MetS and hidradenitis suppurativa is well known, although the relationship between MetS and various autoimmune or inflammatory diseases has only recently attracted interest. Some inflammatory skin diseases, such as vitiligo, scleredema, recurrent aphthous stomatitis, Behçet disease, rosacea, necrobiosis lipoidica, granuloma annulare, skin tags, knuckle pads, and eruptive xanthomas, have possible associations with MetS...
January 2018: Clinics in Dermatology
https://www.readbyqxmd.com/read/29238414/oral-manifestations-in-pediatric-patients-with-coeliac-disease-a-review-article
#12
Viviana Marisa Pereira Macho, Ana Sofia Coelho, Diana Maria Veloso E Silva, David José Casimiro de Andrade
Background: Coeliac disease is a chronic enteropathy that remains a challenge for the clinician, due to its atypical manifestations and etiopathogenic complexity. Objective: This article intends to describe the oral characteristics of Coeliac Disease in children in order to facilitate their management in the dental office. Methods: A review of the literature was performed electronically in PubMed (PubMed Central, and MEDLINE) for articles published in English from 2000 to April of 2017...
2017: Open Dentistry Journal
https://www.readbyqxmd.com/read/29238022/-coexistence-of-takayasu-s-arteritis-and-inflammatory-colitis-detected-by-fluorodeoxyglucose-positron-emission-tomography
#13
Yoshiro Horai, Shota Kurushima, Takashi Igawa, Kunihiro Ichinose, Hideki Nakamura, Atsushi Kawakami
  A woman in her thirties was diagnosed as Takayasu's arteritis (TAK) by dilatation, wall thickness of her abdominal aorta in contrast-enhanced computed tomography. Although she didn't have any subjective bowel symptoms, fluorodeoxyglucose (FDG)-positron emission tomography (PET) also revealed uptake of FDG in descending colon, and colonoscopy revealed aphthous colitis. After the start of steroid therapy, both arteritis and colitis were improved. FDG-PET can detect TAK and inflammatory bowel diseases at an early stage...
2017: Nihon Rinshō Men'eki Gakkai Kaishi, Japanese Journal of Clinical Immunology
https://www.readbyqxmd.com/read/29208798/a-clinical-and-microbiological-evaluation-of-helicobacter-pylori-in-recurrent-aphthous-stomatitis
#14
Kamala Rajendra, Sadananda M Purnachandra, Parthkumar C Patel, Jochima Cota, Venkat R Singh, Ankur Vatsal
AIM: The aim of this study is to evaluate the association of Helicobacter pylori in recurrent aphthous stomatitis (RAS) with or without peptic ulcer. MATERIALS AND METHODS: A total of 42 patients were selected for the present study from outpatient Department of Oral Medicine, and divided into control (group I) and test groups (groups II, III). A total number of 15 patients suffering from RAS based on history and clinical examination was selected as group II. A total number of 12 patients suffering concomitantly from RAS and duodenal ulcer based on history and clinical examination were selected as group III...
December 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29207836/recurrent-aphthous-stomatitis-an-assessment-of-antioxidant-levels-in-plasma-and-saliva
#15
J S Jesija, Saraswathi Gopal, Hugh P Skiel
Introduction: Recurrent Aphthous Stomatitis (RAS) is a common oral mucosal disorder that affects 20% of the population worldwide. Factors such as trauma, stress, genetic, hypersensitivity, nutrition, immune disturbance and hormonal imbalance may disturb the oxidant and antioxidant balance of an organism and precipitate RAS, but the relationships are poorly understood. Aim: The purpose of this study was to evaluate the antioxidant status in plasma and saliva of patients with RAS...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29207559/tooth-wear-is-frequent-in-adult-patients-with-celiac-disease
#16
Massimo Amato, Fabiana Zingone, Mario Caggiano, Paola Iovino, Cristina Bucci, Carolina Ciacci
(1) Background: Celiac disease (CD) patients can be affected by mouth and tooth disorders, which are influenced by their gluten-free diet. The aim of our research was to evaluate the pathological conditions of the stomatognathic system observed in celiac patients on a gluten-free diet. (2) Methods: we consecutively recruited celiac patients on a gluten-free diet at our celiac center, as well as healthy volunteers. Two dentists examined all patients/controls and checked them for any mouth disorder. (3) Results: Forty-nine patients affected by celiac disease (age at test 31...
December 4, 2017: Nutrients
https://www.readbyqxmd.com/read/29203159/long-term-follow-up-of-tonsillectomy-efficacy-in-children-with-pfapa-syndrome
#17
Ozturk Aktas, Hande Gurbuz Aytuluk, Sebla Kumas Caliskan, Omer Erdur, Ahmet Adnan Cirik
INTRODUCTION: The role of tonsillectomy in the periodic fever, aphthous stomatitis, pharyngitis, and adenitis, PFAPA syndrome, is controversial. Although some studies reported high success rates with tonsillectomy, further investigations are needed with larger numbers of patients. OBJECTIVE: To seek the long-term outcomes of tonsillectomy in PFAPA syndrome. METHODS: Case series; multi-center study. The study comprised 23 patients with PFAPA syndrome who underwent surgery (tonsillectomy with or without adenoidectomy) between January 2009 and November 2014...
November 21, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29202564/systematic-review-the-efficacy-of-topical-hyaluronic-acid-on-oral-ulcers
#18
M Casale, A Moffa, P Vella, V Rinaldi, M A Lopez, V Grimaldi, F Salvinelli
The management of oral ulcers is a challenge for clinicians. Whilst there is widespread use of topical corticosteroids, antibiotics and antimicrobial, there is only weak evidence for the effectiveness of any of the topical treatments. Hyaluronic Acid (HA) has been recently proposed for topical administration in the treatment of oral ulcers and other painful oral lesions. The aim of the study is to systematically review the published literature regarding all the therapeutic effects of HA on painful oral lesions such as oral ulcers and oral lichen planus...
December 4, 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29194792/mucocutaneous-manifestations-of-inflammatory-bowel-disease-in-central-china-a-single-center-study
#19
C X Kou, Y Y Zhang, G W Li, J Li, Q T Kong, J Chen, F Liu, M Zhang, F Y Wang, Y Jiang, L Y Hao, J A Ren, H Sang
Inflammatory bowel disease (IBD) is a group of idiopathic inflammatory conditions affecting the gastrointestinal tract, which consists of Crohn's disease (CD) and ulcerative colitis (UC). IBD has multiple extraintestinal manifestations (EIMs), and the prevalence of mucocutaneous manifestations in IBD has been reported as 21%-41%1 . This study aimed at investigating the prevalence of mucocutaneous manifestations (recurrent aphthous ulcer [RAU], erythema nodosum [EN], psoriasis and pyoderma gangrenosum [PG]) of IBD and analyzing of the associations of diseases in a large treatment center of central China...
December 1, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29178716/clinical-evaluation-of-a-toothpaste-containing-lysozyme-for-the-treatment-of-recurrent-aphthous-stomatitis-a-3-month-double-blind-randomized-study
#20
Yanxiong Shao, Haiwen Zhou
PURPOSE: To assess the efficacy and safety of a toothpaste containing lysozyme for the treatment of minor recurrent aphthous stomatitis (MiRAS) in a 3-month clinical trial. METHODS: 71 participants with MiRAS were recruited to this randomized, parallel-controlled, double-blind clinical trial. Participants were allocated randomly to the test group or the control group. Demographic data and pain score (visual analogue scale, VAS) were recorded at baseline. Healing time of MiRAS, recurrence frequency and side effects were recorded at the 1-, 2- and 3-month follow-up visits...
December 2016: American Journal of Dentistry
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