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https://www.readbyqxmd.com/read/28062049/efficacy-and-safety-of-chinese-patent-medicines-in-the-treatment-of%C3%A2-recurrent-aphthous-stomatitis-a-systematic-review
#1
REVIEW
Peiru Zhou, Qinghua Mao, Hong Hua, Xiaosong Liu, Zhimin Yan
BACKGROUND: Recurrent aphthous stomatitis (RAS) is the most common chronic oral mucosal condition of the oral cavity. Investigators in clinical trials have evaluated the effectiveness of Chinese patent medicines in the treatment of RAS. However, the results are conflicting rather than conclusive. To evaluate the efficacy and safety of Chinese patent medicines for the treatment of RAS, the authors conducted a systematic review. TYPES OF STUDIES REVIEWED: The authors searched 9 electronic databases to identify randomized controlled trials (RCTs) or potential clinical controlled trials (CCTs), published in any language, in which the investigators compared Chinese patent medicines with vitamin tablets or placebos for the treatment of RAS...
January 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28054386/enzymatic-antioxidants-status-in-patients-with-recurrent-aphthous-stomatitis
#2
Zichuan Zhang, Shan Li, Huiqing Fang
BACKGROUND: Oxidative stress (OS) has been thought to play a main role in the etiopathogenesis of recurrent aphthous stomatitis (RAS), which is one of the most common oral mucosal diseases characterized by recurrent and painful oral ulcers. The aim of this investigation was to evaluate the enzymatic antioxidants status in patients with RAS in the active stage and remission stage. METHODS: Ninety seven patients with idiopathic minor RAS and 102 race, age and gender-matched healthy individuals were recruited...
January 5, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28045325/oral-manifestations-of-gastrointestinal-diseases-in-children-part-4-coeliac-disease
#3
C Mantegazza, M Paglia, F Angiero, R Crippa
Alterations within the oral cavity can be the first sign of systemic diseases and may thus allow for an early diagnosis and treatment. In particular, being the oral cavity part of the gastrointestinal system, oral alterations can be an expression of a gastrointestinal disease. Dental enamel hypoplasia and aphthous ulcers have been found to be more common in children with coeliac disease compared with the general population and to regress after the patient is started on a gluten free-diet. A prompt recognition of systemic diseases through a careful examination of the oral cavity could allow the child to have appropriate investigations and to be treated in a timely fashion...
December 2016: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28035659/is-there-a-role-of-food-additives-in-recurrent-aphthous-stomatitis-a-prospective-study-with-patch-testing
#4
Duygu Gülseren, Asli Hapa, Sibel Ersoy-Evans, Gonca Elçin, Ayşen Karaduman
BACKGROUND: Recurrent aphthous stomatitis (RAS) is a common disease of the oral mucosa with an unknown etiology. This study aimed to determine if food additives play a role in the etiology of RAS as well as to determine if patch testing can be used to detect which allergens cause RAS. METHODS: This prospective study included 24 patients with RAS and 22 healthy controls. All the participants underwent patch testing for 23 food additives. RESULTS: In total, 21 (87...
December 30, 2016: International Journal of Dermatology
https://www.readbyqxmd.com/read/28008393/status-of-neutrophils-lymphocytes-and-platelets-in-patients-with-recurrent-aphthous-stomatitis-a-retrospective-study
#5
Suat Terzi, Engin Dursun, Abdulkadir Özgür, Enes Yiğit, Zerrin Özergin-Coşkun, Özlem Çelebi-Erdivanl, Münir Demirci
INTRODUCTION: The aim of this study was to evaluate the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and mean platelet volume (MPV) in patients with recurrent aphthous stomatitis (RAS). MATERIALS AND METHODS: Eighty patients who were diagnosed with RAS between January 2014 and January 2016 were included in this study. Eighty age- and gender-matched healthy subjects were also enrolled as a control group. Neutrophil, lymphocyte, and platelet counts were compared between groups, in addition to NLR, PLR, and MPV values...
November 2016: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28001092/familial-mediterranean-fever-with-p369s-r408q-exon3-variant-in-pyrin-presenting-as-symptoms-of-pfapa
#6
Keiko Yamagami, Tomoyuki Nakamura, Ryota Nakamura, Yusuke Hanioka, Kaori Seki, Hiroshi Chiba, Keiko Kobayashi, Kazunaga Agematsu
Familial Mediterranean fever (FMF) can be classified into typical and incomplete/atypical types. Periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis (PFAPA) syndrome-like symptoms has been found in atypical type carrying P369S-R408Q mutations in the responsible gene MEFV. A 28-year-old female with recurrent fever and her young sisters and mother, all of whom had tonsillectomy for tonsillitis, carried heterozygous alterations involving E148Q/P369S/R408Q. A diagnosis of atypical FMF, MEFV exon3 variants with PFAPA syndrome-like symptoms, was made...
December 21, 2016: Modern Rheumatology
https://www.readbyqxmd.com/read/27997341/mumps-measles-and-rubella-vaccination-in-children-with-pfapa-syndrome
#7
Barbara Kraszewska-G Omba, Agnieszka Matkowska-Kocjan, Katarzyna Mi Kiewicz, Zofia Szyma Ska-Toczek, Marta Wójcik, Dorota Bany, Leszek Szenborn
: There is no published data regarding immunologic response to vaccinations in children with PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis). The aim of this study was to evaluate mumps, measles and rubella immunity in children with PFAPA. 31 children with PFAPA syndrome and 22 healthy children (control group - CG) were recruited to the study. All children were previously vaccinated with one dose of MMR vaccine according to the Polish obligatory vaccination schedule...
November 21, 2016: Vaccine
https://www.readbyqxmd.com/read/27982000/gastrointestinal-diseases-and-their-oro-dental-manifestations-part-1-crohn-s-disease
#8
C X W Tan, H S Brand, N K H de Boer, T Forouzanfar
Widely varying prevalence rates of oral lesions in patients with Crohn's disease have been reported, ranging from 0.5% to 37%. These manifestations may coincide with or precede intestinal symptoms. Oral manifestations can be classified as specific lesions, when macroscopic examination shows similar changes to those observed endoscopically in the intestine, and non-specific lesions including aphthous ulcerations. The most frequently observed oral lesions are oedema, ulcers and hyperplastic lesions on the buccal mucosa...
December 16, 2016: British Dental Journal
https://www.readbyqxmd.com/read/27965713/short-term-efficacy-of-pudilan-keyanning-toothpaste-in-treatment-of-minor-recurrent-aphthous-ulcers
#9
Yingming Yang, Tao Zhang, Zibo Dong, Yang Wu, Xiao Hong, Tao Hu
Aim. To examine the potential of Pudilan Keyanning toothpaste (PKT) to treat minor aphthous ulcers (MiAU). Method. A double-blind clinical trial was conducted in which 80 volunteers were randomly assigned to the PKT group (N = 40) or the control group (N = 40). The control group used a placebo toothpaste containing no Pudilan extract. At baseline, after 3 days, and after 6 days the following parameters were recorded for the target ulcers: healing rate, healing period, pain (visual analogue scale, VAS), areas of the target ulcerated lesions, degree of exudation, and hyperemia...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27957263/different-modalities-for-treatment-of-recurrent-aphthous-stomatitis-a-randomized-clinical-trial
#10
Sherine A Nasry, Hanaa M El Shenawy, Dina Mostafa, Nagwa M Ammar
BACKGROUND: The underlying etiology of recurrent aphthous stomatitis (RAS) is unclear and treatment aims to provide symptomatic and faster relief. This study compared the efficacy of diode laser, a herbal combination of Acacia nilotica and Licorice (A and L) and Amlexanox in the management of RAS. MATERIAL AND METHODS: Sixty patients with minor aphthae were selected and randomly divided into four groups of 15 each. Group I and II received adhesive preparations of a herbal mixture of A and L and a 2 mg Amlexanox paste respectively, group III received diode laser and the fourth group (control) used a placebo...
December 2016: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/27935125/clinical-phenotype-of-recurrent-aphthous-stomatitis-and-interleukin-1%C3%AE-genotype-in-a-polish-cohort-of-patients
#11
Zuzanna Ślebioda, Ewa Krawiecka, Marta Rozmiarek, Elżbieta Szponar, Anna Kowalska, Barbara Dorocka-Bobkowska
BACKGROUND: The aim of this study was to evaluate the relation between a clinical profile and the interleukin-1β (IL-1β) genotype in a Polish cohort of patients with RAS. METHODS: One hundred and four patients with RAS were enrolled in the study and all were subject to an oral examination. The severity of RAS was assessed according to the clinical type of the disease, the number of lesions per flare-up and the length of intervals between the episodes. The genotyping of two SNPs of the IL-1β gene, IL-1β c...
December 9, 2016: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/27931995/descriptive-epidemiology-of-deployment-related-medical-conditions-and-shipboard-training-related-injuries-in-a-chinese-navy-population
#12
R-R Qi, J-Q Wang, L-L Pan, W Zhou, J-L Liu, J-T Ju, Y-L Cai
OBJECTIVES: To investigate the deployment-related medical conditions and shipboard tactical training-related injuries in a Chinese Navy population. STUDY DESIGN: A retrospective study with the Chinese Navy was conducted. METHODS: The medical records of 1543 Navy crewmembers from 2011 to 2015 were collected. The distribution and incidence rate (IR) of different types of medical conditions were provided and compared between the Aden Gulf deployment and nondeployment periods...
December 2016: Public Health
https://www.readbyqxmd.com/read/27921409/hla-drb-and-hla-dqb-allele-and-haplotype-frequencies-in-iranian-patients-with-recurrent-aphthous-stomatitis
#13
Shamsolmoulouk Najafi, Mahsa Mohammadzadeh, Alireza Zare Bidoki, Ghasem Meighani, Saeed Aslani, Mahdi Mahmoudi, Nima Rezaei
Recurrent aphthous stomatitis (RAS) is known as the most common chronic disease of the oral cavity, which affects a range of 5-25% of the population. RAS appears to be associated with some human leukocyte antigen (HLA) class II alleles and haplotypes. This study attempts to survey the distribution of HLA-DRB and -DQB alleles among Iranian RAS patients and healthy controls. In order to evaluate the association of HLA-DR and DQ alleles and haplotypes, 54 patients with RAS and 100 unrelated healthy subjects as control group were investigated...
August 2016: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/27920889/lack-of-association-between-interleukin-12-gene-polymorphisms-and-recurrent-aphthous-stomatitis
#14
Isaac Firouze Moqadam, Shamsolmoulouk Najafi, Mahsa Mohammadzadeh, Alireza Zare Bidoki, Hila Yousefi, Elham Farhadi, Arghavan Tonekaboni, Ghasem Meighani, Mohsen Mohammadzadeh, Ali Akbar Amirzargar, Nima Rezaei
No abstract text is available yet for this article.
October 2016: Avicenna Journal of Medical Biotechnology
https://www.readbyqxmd.com/read/27904594/relationship-between-articular-and-nonarticular-manifestations-in-inflammatory-bowel-diseases
#15
Alimohammad Fatemi, Hourossadat Hashemi Jazi, Mohammad Hasan Emami, Amir Kazemizadeh, Hamid Tavakkoli, Abbas Smiley
BACKGROUND: Musculoskeletal manifestations (MSM) of inflammatory bowel diseases (IBDs) are usually the most frequent extraintestinal manifestations. However, they are not paid enough attention during regular office visits. This cross-sectional study aimed to draw a clinical picture of MSM and their relationships with other findings in patients with IBD. MATERIALS AND METHODS: Patients of our IBD cohort between March 2012 and September 2013 were consecutively evaluated...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27903265/associations-among-oral-health-related-quality-of-life-subjective-symptoms-clinical-status-and-self-rated-oral-health-in-japanese-university-students-a-cross-sectional-study
#16
Mayu Yamane-Takeuchi, Daisuke Ekuni, Shinsuke Mizutani, Kota Kataoka, Ayano Taniguchi-Tabata, Tetsuji Azuma, Michiko Furuta, Takaaki Tomofuji, Yoshiaki Iwasaki, Manabu Morita
BACKGROUND: The present study aimed to elucidate the associations among self-rated oral health, clinical oral health status, oral health behaviors, subjective oral symptoms, and oral health-related quality of life (OHRQoL) in a group of Japanese university students. METHODS: Of 2051 participants, 2027 (98.83%) students received an optional oral examination and answered a questionnaire including items regarding age, sex, self-rated oral health, oral health behaviors, subjective oral symptoms, and OHRQoL [The Oral Health Impact Profile (OHIP)-14]...
November 30, 2016: BMC Oral Health
https://www.readbyqxmd.com/read/27896917/on-the-pathogenesis-of-mtor-associated-stomatitis-mias-studies-using-an-organotypic-model-of-the-oral-mucosa
#17
Stephen Sonis, Paulette Wright Andreotta, Gregory Lyng
OBJECTIVE: mTOR inhibitor treatment of solid cancers is associated with mTOR inhibitor-associated stomatitis (mIAS) a common, significant, dose-limiting toxicity, with aphthous-like lesions. Our objective was to assess the utility of a new organotypic model in defining mIAS' pathogenesis. MATERIALS AND METHODS: The effect of everolimus on organotypic human oral mucosa was studied. Sterile specimens were assessed 24 hr and 48 hr after exposure to varying concentrations of everolimus...
November 29, 2016: Oral Diseases
https://www.readbyqxmd.com/read/27896868/crohn-s-disease-should-be-considered-in-children-with-inflammatory-oral-lesions
#18
REVIEW
Anna Skrzat, Dorota Olczak-Kowalczyk, Anna Turska- Szybka
: This systematic review presents the oral manifestations of paediatric Crohn's disease. Our review of 28 papers published from 2000 to 2015 showed that the prevalence of oral manifestations was 10 to 80%. Specific symptoms included mucosal tags, swelling of the lips, cheeks and gingiva and cobblestoning mucosa. Non-specific symptoms included aphthous-like ulcers, angular cheilitis, lip fissuring and gingivitis. CONCLUSION: The oral manifestations of Crohn's disease might precede intestinal inflammation or coincide with it...
November 29, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27891490/is-optimal-management-of-recurrent-aphthous-stomatitis-possible-a-reality-check
#19
REVIEW
Shesha Prasad Ranganath, Anuradha Pai
Recurrent Aphthous Stomatitis (RAS) is a condition in which aphthous ulcers repeatedly occur in the oral cavity. It is prevalent in developed countries, occurring in all ages, geographic regions and races and about 80% of people have one episode of oral aphthous ulcers before the age of 30 years. With no laboratory procedures to confirm the diagnosis, treatment is mainly empirical in nature and focuses on short-term symptomatic management. Although numerous treatment modalities have been recommended, only a few are evidence based and can be considered for the optimal management of RAS...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27889847/diagnostic-value-of-small-bowel-capsule-endoscopy-in-isolated-ileitis-a-capentry-study
#20
Hyun Seok Lee, Yun Jeong Lim, Ki Nam Shim, Chang Mo Moon, Hyun Joo Song, Jin Oh Kim, Seong Ran Jeon, Dae Young Jung, Ji Hyun Kim, Kyeong Ok Kim, Bo-In Lee
BACKGROUND: Capsule endoscopy (CE) has proven to be highly effective at detecting small bowel lesions, but studies regarding the diagnostic impact of CE on ileitis are rare. AIMS: We evaluated the diagnostic value of small bowel CE for isolated ileitis observed during ileocolonoscopy. METHODS: The CE results in 137 patients initially diagnosed with ileitis without colonic mucosal abnormalities on ileocolonoscopy at one of eight tertiary referral centers between October 2002 and June 2015 were retrospectively analyzed...
November 26, 2016: Digestive Diseases and Sciences
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