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Central serous retinopathy

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https://www.readbyqxmd.com/read/29600987/the-use-of-optical-coherence-tomography-angiography-for-detecting-choroidal-neovascularization-compared-to-standard-multimodal-imaging
#1
T Soomro, J Talks
PurposeTo assess OCT angiography (OCTA) effectiveness at detecting choroidal neovascularization (CNV) in cases of suspected neovascular age related macular degeneration (nAMD), chronic central serous retinopathy (cCSR) and pathological myopia compared to FFA and how it compares to a multimodal approach (OCT, FFA and ICGA) for detecting the vascular network.MethodsThis was a retrospective observational cohort study of patients who had clinical and/or OCT findings suggestive of CNV, having further investigation with FFA, with or without ICG, and had same day OCTA using the Heidelberg Spectralis OCT2 beta angiography module...
March 30, 2018: Eye
https://www.readbyqxmd.com/read/29576900/three-cases-of-congenital-retinal-macrovessel-one-coexisting-with-cilioretinal-artery
#2
Bayram Gülpamuk, Pınar Kaya, Mehmet Yasin Teke
In this report, we describe three cases of retinal macrovessel. Two of the three patients presented to our clinic for annual eye exam and had no visual complaints. The third patient presented because of vision loss in the left eye. Two patients had 20/20 best corrected visual acuity in both eyes and the third patient had 20/20 in the right eye, 20/25 in the left eye. Pupillary exams were normal. Slit-lamp examinations of the anterior segment were unremarkable. Fundus examination revealed macrovessels in the left eyes of two patients and in the right eye of one patient...
February 2018: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29559493/acute-exudative-polymorphous-vitelliform-maculopathy-syndrome-natural-history-and-evolution-of-fundal-and-oct-images-over-time
#3
Patrick Murtagh, Maxwell Treacy, Kirk Stephenson, Ian Dooley
A 33-year-old man presented with a 10-day history of bilateral blurred vision on a background of a prodromal influenza-like illness. Ocular Coherence Tomography (OCT) and fundal examination coincided with a diagnosis of atypical central serous retinopathy. The patient's symptoms worsened during follow-up, and he was started on steroids. Subsequent fundal examination revealed yellow deposits in a honeycomb pattern and hard exudates in the perimacular region. Serial OCTs revealed progression of bilateral macular intraretinal and subretinal fluid...
March 20, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29551993/gonadal-hormones-and-retinal-disorders-a-review
#4
REVIEW
Raffaele Nuzzi, Simona Scalabrin, Alice Becco, Giancarlo Panzica
Aim: Gonadal hormones are essential for reproductive function, but can act on neural and other organ systems, and are probably the cause of the large majority of known sex differences in function and disease. The aim of this review is to provide evidence for this hypothesis in relation to eye disorders and to retinopathies in particular. Methods: Epidemiological studies and research articles were reviewed. Results: Analysis of the biological basis for a relationship between eye diseases and hormones showed that estrogen, androgen, and progesterone receptors are present throughout the eye and that these steroids are locally produced in ocular tissues...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29442094/a-potential-side-effect-of-oral-topical-steroids-central-serous-chorioretinopathy
#5
Saranya George, Anita Balan
Topical corticosteroids are some of the most common drugs used in oral medicine for treating atrophic and erosive lesions that affect the mucosa. Adverse effects of these drugs include oral candidiasis with associated burning mouth and hypogeusia, hypersensitive reactions to the drug, and inhibition of the hypothalamic-pituitary-adrenal axis and secondary adrenal insufficiency. The ocular side effects of oral topical steroids are less documented. This short communication describes a case of central serous retinopathy that developed following administration of oral topical steroid...
January 2018: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/29425345/recurrent-central-serous-retinopathy-with-permanent-visual-loss-in-a-u-s-naval-fighter-pilot
#6
Ryan R Richmond, Matthew Rings
Central serous retinopathy (CSR) is a disease process that involves accumulation of serous fluid within the macular retina. This fluid accumulation can temporarily or permanently disrupt vision and in many patients is often a recurrent problem. This case describes recurrent CSR in an experienced U.S. Naval F/A-18 fighter pilot. The patient had been troubled by recurrent CSR for several years which required him to be removed from a flying status. After several episodes and treatment with laser photocoagulation and finasteride, the patient's vision and disease process stabilized, but with permanent defective visual acuity in the right eye...
February 7, 2018: Military Medicine
https://www.readbyqxmd.com/read/29403598/sub-internal-limiting-membrane-cavity-following-valsalva-retinopathy-resembling-central-serous-chorioretinopathy
#7
Koushik Tripathy, Rohan Chawla, Laxman Vekaria, Yog Raj Sharma
No abstract text is available yet for this article.
January 2018: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29403592/management-of-retinal-diseases-in-pregnant-patients
#8
REVIEW
Julie M Rosenthal, Mark W Johnson
Pregnancy leads to significant changes in the body, which potentially affect the retina. Pregnancy can induce disease, such as that seen in hypertensive retinopathy and choroidopathy. It can cause exudative retinal detachments in the HELLP syndrome (hemolysis, elevated liver enzymes and low platelets), disseminated intravascular coagulation (DIC), and thrombotic thrombocytopenic purpura (TTP), and provoke arterial and venous retinal occlusive disease. Pregnancy may also exacerbate pre-existing retinal disease, such as idiopathic central serous chorioretinopathy (ICSC) and diabetic retinopathy...
January 2018: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29371007/efficacy-and-safety-of-ranibizumab-0-5-mg-for-the-treatment-of-macular-edema-resulting-from-uncommon-causes-twelve-month-findings-from-prometheus
#9
Giovanni Staurenghi, Timothy Y Y Lai, Paul Mitchell, Sebastian Wolf, Andreas Wenzel, Jun Li, Amitabha Bhaumik, Philip G Hykin
PURPOSE: To evaluate the efficacy and safety of ranibizumab 0.5 mg in adult patients with macular edema (ME) resulting from any cause other than diabetes, retinal vein occlusion, or neovascular age-related macular degeneration. DESIGN: A phase 3, 12-month, double-masked, randomized, sham-controlled, multicenter study. PARTICIPANTS: One hundred seventy-eight eligible patients aged ≥18 years. METHODS: Patients were randomized 2:1 to receive either ranibizumab 0...
January 19, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29260123/photoreceptor-disruption-and-vision-loss-associated-with-central-serous-retinopathy
#10
Lynn W Sun, Joseph Carroll, Brandon J Lujan
Purpose: To present ophthalmic imaging findings in the case of a 40-year-old male with sustained visual loss after a single episode of acute central serous retinopathy (CSR). Observations: A male subject presented with visual acuity decline to 20/50 OS and was diagnosed with acute CSR. The initial pigment epithelial detachment and subretinal fluid resolved within 6 weeks, but visual acuity remained impaired. Using directional optical coherence tomography (D-OCT) and confocal and split-detector adaptive optics scanning light ophthalmoscopy (AOSLO), we imaged pathologic alterations in the photoreceptor mosaic of the affected eye...
December 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29161237/bilateral-visual-field-defects-in-a-patient-treated-with-the-mek-and-braf-inhibitors-trametinib-and-dabrafenib-for-melanoma-of-unknown-origin
#11
Jakob Siedlecki, Marc Mackert, Armin Wolf, Carola Berking, Siegfried G Priglinger, Kirsten Eibl-Lindner
INTRODUCTION: Although the introduction of BRAF and MEK inhibitors has greatly enhanced treatment possibilities in advanced BRAFV600-mutated melanoma, class-related toxicities are rather frequent and often involve the eye. Ophthalmologic side effects most commonly include central/diffuse serous retinopathy and retinal vein occlusion. Affection of the optic nerve head however has not been described clinically. CASE REPORT: A 29-year-old man presented in our eye clinic with bilateral blurred vision...
April 17, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29020426/aflibercept-in-serous-foveal-detachment-in-dome-shaped-macula-short-term-results-in-a-retrospective-study
#12
Giovanni Giacomelli, Rita Mencucci, Andrea Sodi, Ilaria Biagini, Giacomo Abbruzzese, Matteo Giuntoli, Stanislao Rizzo, Gianni Virgili
BACKGROUND AND OBJECTIVE: To evaluate short-term efficacy of intravitreal aflibercept (Eylea; Regeneron, Tarrytown, NY) in serous foveal detachment (SFD) in dome-shaped macula (DSM). PATIENTS AND METHODS: A retrospective, noncomparative case series. Three monthly aflibercept injections were administered. Early Treatment Diabetic Retinopathy Study best-corrected visual acuity (BCVA), optical coherence tomography central subfield thickness (CST), and subretinal fluid (SRF) at baseline and at 2 months and 4 months after the last injection were considered for statistical analysis...
October 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28942764/ocular-manifestations-of-obstructive-sleep-apnea
#13
Matthew Santos, R Jeffrey Hofmann
STUDY OBJECTIVES: Obstructive sleep apnea (OSA) incurs a host of systemic side effects. The eyes are particularly susceptible to both mechanical and vascular sequelae of the disease. This paper outlines the ocular manifestations of sleep apnea. The authors hope to increase awareness of the ocular complications of this common disorder and increase communication and co-management between eye-care providers and sleep specialists alike. METHODS: Data were collected from PubMed and the Brown University Library Collection...
November 15, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28767907/retinal-changes-in-solid-organ-and-bone-marrow-transplantation-patients
#14
Fernando Korn Malerbi, Sergio Henrique Teixeira, Luis Gustavo Gondo Hirai, Nilson Hideo Matsudo, Adriano Biondi Monteiro Carneiro
Objective: To evaluate retinal changes in patients who underwent solid organ or bone marrow transplantation. Methods: A retrospective analysis of medical records of patients evaluated from February 2009 to December 2016. All patients included underwent funduscopy. Clinical and demographic data regarding transplantation and ophthalmological changes were collected. Results: A total of 126 patients were analyzed; of these, 108 underwent transplantation and 18 were in the waiting list...
April 2017: Einstein
https://www.readbyqxmd.com/read/28752697/clinical-features-of-pregnancy-associated-retinal-and-choroidal-diseases-causing-acute-visual-disturbance
#15
Young Joo Park, Kyu Hyung Park, Se Joon Woo
PURPOSE: To report clinical features of patients with retinal and choroidal diseases presenting with acute visual disturbance during pregnancy. METHODS: In this retrospective case series, patients who developed acute visual loss during pregnancy (including puerperium) and visited a tertiary hospital from July 2007 to June 2015, were recruited by searching electronic medical records. Patients were categorized according to the cause of visual loss. Clinical features and required diagnostic modalities were analyzed in the retinal and choroidal disease group...
August 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28709702/clinical-and-morphologic-characteristics-of-mek-inhibitor-associated-retinopathy-differences-from-central-serous-chorioretinopathy
#16
COMPARATIVE STUDY
Jasmine H Francis, Larissa A Habib, David H Abramson, Lawrence A Yannuzzi, Murk Heinemann, Mrinal M Gounder, Rachel N Grisham, Michael A Postow, Alexander N Shoushtari, Ping Chi, Neil H Segal, Rona Yaeger, Alan L Ho, Paul B Chapman, Federica Catalanotti
PURPOSE: To investigate the clinical and morphologic characteristics of serous retinal disturbances in patients taking mitogen-activated protein kinase kinase (MEK) inhibitors. PARTICIPANTS: A total of 313 fluid foci in 50 eyes of 25 patients receiving MEK inhibitors for treatment of their metastatic cancer, who had evidence of serous retinal detachments confirmed by optical coherence tomography (OCT). DESIGN: Single-center, retrospective cohort study...
December 2017: Ophthalmology
https://www.readbyqxmd.com/read/28674835/photodynamic-therapy-in-chronic-central-serous-chorioretinopathy-with-subretinal-fluid-outside-the-fovea
#17
Elon H C van Dijk, Greet Dijkman, Camiel J F Boon
PURPOSE: To assess the efficacy of photodynamic therapy (PDT) in patients with chronic central serous chorioretinopathy (cCSC), in whom subretinal fluid (SRF) was solely present outside the foveal area. METHODS: In this retrospective study, 16 eyes of 15 cCSC patients who received half-dose PDT because of notable subjective visual complaints due to the presence of extrafoveal SRF, were included. An ophthalmic examination was performed before treatment, including Early Treatment Diabetic Retinopathy Study best-corrected visual acuity measurement, applanation tonometry, slit-lamp examination, and indirect ophthalmoscopy, followed by multimodal imaging, including fundus photography, fundus autofluorescence, spectral-domain optical coherence tomography (OCT), enhanced-depth imaging OCT of the choroid, fluorescein angiography, and indocyanine green angiography...
October 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28306346/risk-factors-for-central-serous-chorioretinopathy-multivariate-approach-in-a-case-control-study
#18
Irini Chatziralli, Stamatina A Kabanarou, Efstratios Parikakis, Alexandros Chatzirallis, Tina Xirou, Panagiotis Mitropoulos
PURPOSE: The purpose of this prospective study was to investigate the potential risk factors associated independently with central serous retinopathy (CSR) in a Greek population, using multivariate approach. MATERIALS AND METHODS: Participants in the study were 183 consecutive patients diagnosed with CSR and 183 controls, matched for age. All participants underwent complete ophthalmological examination and information regarding their sociodemographic, clinical, medical and ophthalmological history were recorded, so as to assess potential risk factors for CSR...
July 2017: Current Eye Research
https://www.readbyqxmd.com/read/28237171/atypical-transient-subretinal-exudation-following-photodynamic-therapy-for-chronic-central-serous-retinopathy-a-case-report
#19
Ahmad Al-Awadi, Efrem D Mandelcorn, Sohel Somani
No abstract text is available yet for this article.
February 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28210185/neoplastic-leptomeningeal-disease-masquerading-as-central-serous-retinopathy-a-case-report
#20
Ibrahim Elaraoud, Hanif J Suleman, Peter Cikatricis, Helen Palmer
A 69-year-old man became aware of people's speech being out of synch with their lip movements alongside persistent headaches, both of which progressively worsened. A few weeks later, he developed progressive and painless visual loss in one eye. Initial neurological evaluation, inflammatory markers and head computed tomography scan were normal. Ophthalmological examination and OCT scan revealed right macular subretinal fluid with choroidal indentation, which prompted urgent further investigations including head MRI revealing extensive leptomeningeal disease...
July 2016: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
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