keyword
MENU ▼
Read by QxMD icon Read
search

meningococcal b vaccine

keyword
https://www.readbyqxmd.com/read/29790460/establishment-of-the-european-meningococcal-strain-collection-genome-library-emsc-gl-for-the-2011-to-2012-epidemiological-year
#1
Holly B Bratcher, Carina Brehony, Sigrid Heuberger, Despo Pieridou-Bagatzouni, Pavla Křížová, Steen Hoffmann, Maija Toropainen, Muhamed-Kheir Taha, Heike Claus, Georgina Tzanakaki, Tímea Erdôsi, Jelena Galajeva, Arie van der Ende, Anna Skoczyńska, Marina Pana, Alena Vaculíková, Metka Paragi, Martin Cj Maiden, Dominique A Caugant
Invasive meningococcal disease surveillance in Europe combines isolate characterisation and epidemiological data to support public health intervention. A representative European Meningococcal Strain Collection (EMSC) of IMD isolates was obtained, and whole genome sequenced to characterise 799 EMSC isolates from the epidemiological year July 2011-June 2012. To establish a genome library (GL), the isolate information was deposited in the pubMLST.org/neisseria database. Genomes were curated and annotated at 2,429 meningococcal loci, including those defining clonal complex, capsule, antigens, and antimicrobial resistance...
May 2018: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/29778515/safety-and-immunogenicity-of-fractional-dose-intradermal-injection-of-two-quadrivalent-conjugated-meningococcal-vaccines
#2
Emile F F Jonker, Mariëtte B van Ravenhorst, Guy A M Berbers, Leo G Visser
BACKGROUND: Vaccination with conjugated meningococcal vaccines is the best way to prevent invasive meningococcal disease. Changes in serogroup epidemiology have led to the inclusion of quadrivalent vaccines in the national immunization programs of several countries, but vaccines are frequently in short supply. Intradermal administration has the potential to increase vaccine availability through dose reduction, without sacrificing efficacy. It has never before been investigated for glycoconjugate meningococcal vaccines...
May 16, 2018: Vaccine
https://www.readbyqxmd.com/read/29772848/increased-vaccination-coverage-among-adolescents-and-young-adults-in-the-district-of-palermo-as-a-result-of-a-public-health-strategy-to-counteract-an-epidemic-panic
#3
Claudio Costantino, Vincenzo Restivo, Gianmarco Ventura, Claudio D'Angelo, Maria Angela Randazzo, Nicolò Casuccio, Mario Palermo, Alessandra Casuccio, Francesco Vitale
During the summer of 2016 four cases of invasive meningococcal disease in rapid succession among young adults in the district of Palermo, Italy, resulting in one death, were widely reported by local and national mass media. The resultant 'epidemic panic' among the general population overloaded the vaccination units of the Palermo district over the following months. Strategies implemented by the Sicilian and local public health authorities to counteract 'meningitis fear' included the following: (a) extension of active and free-of-charge anti-meningococcal tetravalent vaccination from age class 12⁻18 to 12⁻30 years old; (b) implementation of vaccination units during normal clinic hours in rooms tailored for vaccine administration; (c) development of informative institutional tools and timely communication throughout local mass media to reassure the general population...
May 17, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29764949/toward-an-improved-meningococcal-serogroup-b-assay
#4
Jan Poolman
Because of diverse sequences and differential expression of surface structures on individual invasive Neisseria meningitidis serogroup B (MenB) strains, predicting the efficacy of MenB vaccines using traditional human serum bactericidal assays (hSBA) is impractical. The meningococcal antigen surface expression (MEASURE) assay uses flow cytometry to quantitate the expression of factor H binding proteins (fHbp) contained in the bivalent rLP2086 MenB vaccine. To date, experience with MEASURE has been lacking, and in a long-awaited article, McNeil et al...
May 15, 2018: MBio
https://www.readbyqxmd.com/read/29751133/the-threat-of-meningococcal-disease-during-the-hajj-and-umrah-mass-gatherings-a-comprehensive-review
#5
REVIEW
Saber Yezli
The Hajj and Umrah mass gatherings represent many of the risk factors for meningococcal disease and have historically been associated with both local and international outbreaks of the disease. The implementation of strict preventative measures including mandatory meningococcal vaccination with the quadrivalent (A,C,Y,W) vaccine has prevented pilgrimage-associated meningococcal outbreaks and significantly reduced the incidence of the disease at these events. However, meningococcal disease remains an important public health threat at the Hajj and Umrah due in part to the evolving nature of the disease, characterized with diverse and varying geographic trends, fluctuations in incidence and shifts in serogroups and genotypes...
May 8, 2018: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/29743304/molecular-characterization-of-invasive-isolates-of-neisseria-meningitidis-in-casablanca-morocco
#6
Aziza Razki, Eva Hong, Khalid Zerouali, Houria Belabbes, Khadija Aitmouss, Aude Terrade, Bahija Zaki, Ala-Eddine Deghmane, Naima Elmdaghri, Muhamed-Kheir Taha
Meningococcal epidemiology may change unpredictably and typing of isolates of Neisseria meningitidis is crucial for the surveillance of invasive meningococcal disease (IMD). Few data are available of the meningococcal epidemiology in countries of North Africa. We aimed to explore the invasive meningococcal isolates from the Casablanca region in Morocco. We used whole genome sequencing (WGS) to characterize 105 isolates from this region during the period 2011-2016. Our data showed that the majority (n=100) of the isolates belonged to serogroup B...
May 9, 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29741515/-assessment-of-health-information-available-online-regarding-meningococcal-b-vaccine-recommendations
#7
Ignacio Hernández-García, Teresa Giménez-Júlvez
OBJECTIVE: The quality of health information online is a concern to governments and users. Our objective was to determine the extent to which the information available online regarding meningococcal B vaccine recommendations adhere to the guidelines of the Spanish Ministry of Health. METHODS: Cross-sectional study carried out in April 2017. The study assessed adherence of information regarding vaccine recommendations to official guidelines. The information was collected via Google with 20 keywords...
May 11, 2018: Revista Española de Salud Pública
https://www.readbyqxmd.com/read/29738508/factors-associated-with-immunization-opinion-leadership-among-men-who-have-sex-with-men-in-los-angeles-california
#8
Ian W Holloway, Robert Bednarczyk, Vincent L Fenimore, Cameron Goldbeck, Elizabeth Wu, Rebecca Himmelstein, Diane Tan, Laura Randall, Chelsea S Lutz, Paula M Frew
We sought to identify the characteristics of men who have sex with men (MSM) who are opinion leaders on immunization issues and to identify potential opportunities to leverage their influence for vaccine promotion within MSM communities. Using venue-based sampling, we recruited and enrolled MSM living in Los Angeles ( N = 520) from December 2016 to February 2017 and evaluated characteristic differences in sociodemographic characteristics, health behaviors, and technology use among those classified as opinion leaders versus those who were not...
May 8, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29717697/adverse-events-following-immunisation-with-a-meningococcal-serogroup-b-vaccine-report-from-post-marketing-surveillance-germany-2013-to-2016
#9
Dirk Mentzer, Doris Oberle, Brigitte Keller-Stanislawski
Background and aimIn January 2013, a novel vaccine against Neisseria meningitidis serogroup B, the multicomponent meningococcal serogroup B vaccine (4CMenB), was approved by the European Medicines Agency. We aimed to evaluate the safety profile of this vaccine. Methods: All adverse events following immunisation (AEFI) reported from Germany since the vaccine's launch in Germany in November 2013 through December 2016 were reviewed and analysed. Results: Through December 2016, a total of 664 individual case safety reports (ICSR) notifying 1,960 AEFI were received...
April 2018: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/29717696/extension-of-french-vaccination-mandates-from-the-recommendation-of-the-steering-committee-of-the-citizen-consultation-on-vaccination-to-the-law
#10
Daniel Lévy-Bruhl, Jean-Claude Desenclos, Sylvie Quelet, François Bourdillon
On 4 December 2017, French parliamentarians passed a law extending the vaccination mandates for children up to 2 years of age from three vaccinations (against diphtheria, tetanus and poliomyelitis) to 11 by adding vaccinations against pertussis, Haemophilus influenza b (Hib), hepatitis B, pneumococcal diseases, meningococcal C diseases, measles, mumps and rubella. This vote follows a recommendation made by the Steering Committee of the Citizen Consultation on Vaccination that took place in 2016. The law applies to all children born after 1 January 2018...
April 2018: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/29702658/use-of-weighted-multivariate-estimates-in-trials-of-multi-serotype-vaccines-to-simplify-interpretation-of-treatment-differences
#11
Merryn Voysey, Andrew J Pollard, Rafael Perera, Shrijana Shrestha, Stephen Thorson, Thomas R Fanshawe
BACKGROUND: Many vaccines contain multiple components. Licensed pneumococcal conjugate vaccines (PCV) contain polysaccharides from 7, 10, or 13 different serotypes of Streptococcus pneumoniae. The main outcomes in randomised trials of pneumococcal vaccines are serotype-specific antibody measures. Comparisons are made between groups for each serotype, resulting in multiple separate comparisons of treatment effects which can be complicated to interpret. We investigated methods for computing the overall difference between vaccine groups across all serotypes...
2018: PloS One
https://www.readbyqxmd.com/read/29695781/the-bexsero-neisseria-meningitidis-serogroup-b-vaccine-antigen-nhba-is-a-high-affinity-chondroitin-sulfate-binding-protein
#12
Tsitsi D Mubaiwa, Lauren E Hartley-Tassell, Evgeny A Semchenko, Christopher J Day, Michael P Jennings, Kate L Seib
Neisseria meningitidis is a Gram-negative bacterial pathogen that causes life threatening meningitis and septicemia. Neisseria Heparin Binding Antigen (NHBA) is an outer membrane protein that binds heparin and heparan sulfate and DNA. This protein is one of the four antigens in the meningococcal serogroup B vaccine Bexsero. In the current study, we sought to define the full glycan-binding repertoire of NHBA to better understand its role in meningococcal pathogenesis and vaccine efficacy. Glycan array analysis revealed binding to 28 structures by recombinant NHBA...
April 25, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29686670/alum-toll-like-receptor-7-adjuvant-enhances-the-expansion-of-memory-b-cell-compartment-within-the-draining-lymph-node
#13
Hoa Thi My Vo, Barbara Christiane Baudner, Stefano Sammicheli, Matteo Iannacone, Ugo D'Oro, Diego Piccioli
Vaccination is one of the most cost-effective health interventions and, with the exception of water sanitization, no other action has had such a major effect in mortality reduction. Combined with other approaches, such as clean water, better hygiene, and health education, vaccination contributed to prevent millions of cases of deaths among children under 5 years of age. New or improved vaccines are needed to fight some vaccine-preventable diseases that are still a threat for the public health globally, as reported also in the Global Vaccine Action Plan (GVAP) endorsed by the World Health Assembly in 2012...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29678594/knowledge-and-attitudes-regarding-category-b-acip-recommendations-among-primary-care-providers-for-children
#14
Allison Kempe, Mandy A Allison, Jessica R MacNeil, Sean T O'Leary, Lori A Crane, Brenda L Beaty, Laura P Hurley, Michaela Brtnikova, Megan C Lindley, Jennifer L Liang, Alison P Albert, Jean C Smith
OBJECTIVE: In 2015, the Advisory Committee on Immunization Practices (ACIP) made a category B recommendation for use of serogroup B meningococcal (MenB) vaccines, meaning individual clinical decision-making should guide recommendations. This was the first use of a category B recommendation pertaining to a large population and the first such recommendation for adolescents. As part of a survey regarding MenB vaccine, our objectives were to assess among pediatricians (Peds) and family physicians (FPs) nationally: 1) knowledge of the meaning of category A versus B recommendations and insurance coverage implications; and 2) attitudes about category A and B recommendations...
April 17, 2018: Academic Pediatrics
https://www.readbyqxmd.com/read/29672552/induction-of-salivary-antibody-levels-in-dutch-adolescents-after-immunization-with-monovalent-meningococcal-serogroup-c-or-quadrivalent-meningococcal-serogroup-a-c-w-and-y-conjugate-vaccine
#15
Mariëtte B van Ravenhorst, Gerco den Hartog, Fiona R M van der Klis, Debbie M van Rooijen, Elisabeth A M Sanders, Guy A M Berbers
BACKGROUND: Meningococcal infection starts with colonisation of the upper respiratory tract. Mucosal immunity is important for protection against acquisition and subsequent meningococcal carriage. In this study, we assessed salivary antibody levels against meningococcal serogroup A (MenA), W (MenW) and Y (MenY) after vaccination with a quadrivalent MenACWY conjugated vaccine. We also compared salivary meningococcal serogroup C (MenC) antibody levels after monovalent MenC and quadrivalent MenACWY conjugated vaccination...
2018: PloS One
https://www.readbyqxmd.com/read/29671067/vaccinations-in-pediatric-kidney-transplant-recipients
#16
REVIEW
Thomas G Fox, Corina Nailescu
Pediatric kidney transplant (KT) candidates should be fully immunized according to routine childhood schedules using age-appropriate guidelines. Unfortunately, vaccination rates in KT candidates remain suboptimal. With the exception of influenza vaccine, vaccination after transplantation should be delayed 3-6 months to maximize immunogenicity. While most vaccinations in the KT recipient are administered by primary care physicians, there are specific schedule alterations in the cases of influenza, hepatitis B, pneumococcal, and meningococcal vaccinations; consequently, these vaccines are usually administered by transplant physicians...
April 18, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29667483/global-epidemiology-of-serogroup-b-meningococcal-disease-and-opportunities-for-prevention-with-novel-recombinant-protein-vaccines
#17
Rodolfo Villena, Marco Aurelio P Safadi, María Teresa Valenzuela, Juan P Torres, Adam Finn, Miguel O'Ryan
Meningococcal disease (MD) is a major cause of meningitis and sepsis worldwide, with a high case fatality rate and frequent sequelae. Neisseria meningitidis serogroups A, B, C, W, X and Y are responsible for most of these life-threatening infections, and its unpredictable epidemiology can cause outbreaks in communities, with significant health, social and economic impact. Currently, serogroup B is the main cause of MD in Europe and North America and one of the most prevalent serogroups in Latin America. Mass vaccination strategies using polysaccharide vaccines have been deployed since the 1970s and the use of conjugate vaccines has controlled endemic and epidemic disease caused by serogroups A, C, W and Y and more recently serogroup B using geographically-specific outer membrane vesicle based vaccines...
April 18, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29644339/molecular-characterization-of-two-sub-family-specific-monoclonal-antibodies-to-meningococcal-factor-h-binding-protein
#18
C Lo Passo, L Zippilli, A Angiolillo, I Costa, I Pernice, R Galbo, F Felici, P T Beernink
Factor H binding protein (FHbp) is a component of two licensed vaccines for prevention of sepsis and meningitis caused by serogroup B meningococci. FHbp binds human Factor H (FH), which contributes to evasion of host immunity and FHbp sequence variants can be classified into two sub-families. Antibodies against FHbp elicit complement-mediated killing and can inhibit recruitment of FH to the bacterial surface. We report epitope mapping studies of two murine IgG mAbs, designated JAR 31 and JAR 36, isolated from a mouse immunized with FHbp in sub-family A, which is present in ∼30-40% of invasive isolates...
April 2018: Heliyon
https://www.readbyqxmd.com/read/29623748/neisseria-meningitidis-disease-associated-clones-in-amazonas-state-brazil
#19
Luciete A Silva, Beatriz Coronato, Jessica Schlackman, Jane W Marsh, Chinelo Ezeonwuka, Andréia C L Fernandes, Victor C Souza, Lirna S da Silva, Elaine F Q de Amorim, Felipe G Naveca, Bernardino C de Albuquerque, Alcirene Amaral, Ana L S Souza, Filipe A Carvalho-Costa, Mustapha M Mustapha, Lee H Harrison, David E Barroso
BACKGROUND: The aim of this study is to describe the molecular epidemiology of Neisseria meningitidis invasive disease before the introduction of serogroup C conjugate vaccine in Amazonas State in 2010. METHODS: Meningococcal disease reported cases were investigated in Amazonas State during the period 2000-2010. N. meningitidis isolates (n = 196) recovered from patients were genotyped by multilocus sequence typing (MLST) and sequencing of porB, porA, fetA, fHbp and penA...
April 6, 2018: Infectious Diseases
https://www.readbyqxmd.com/read/29620722/immunogenicity-and-reactogenicity-of-dtpa-hbv-ipv-hib-and-phid-cv-when-co-administered-with-menacwy-tt-in-infants-results-of-an-open-randomized-trial
#20
Jose Manuel Merino Arribas, Alfonso Carmona Martínez, Michael Horn, Xavier Maria Perez Porcuna, Maria Del Carmen Otero Reigada, Josep Marès Bermúdez, Fernando Centeno Malfaz, Mariano Miranda, Maria Mendez, Miguel Angel Garcia Cabezas, Wittermann Christoph, Gerhard Bleckmann, Thomas Fischbach, Devayani Kolhe, Marie Van der Wielen, Yaela Baine
BACKGROUND: This study evaluated the immunogenicity and reactogenicity of a combined diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus virus-Haemophilus influenzae type b vaccine (DTPa-HBV-IPV/Hib) and a 10-valent pneumococcal conjugate vaccine (PHiD-CV) co-administered with a quadrivalent meningococcal conjugate vaccine (MenACWY-TT) in infants/toddlers. METHODS: In this open, controlled, phase III study (NCT01144663), 2095 healthy infants were randomised (1:1:1:1) into 4 groups to receive MenACWY-TT at 2, 3, 4 and 12 months of age, or MenACWY-TT, MenC-CRM197 or MenC-TT at 2, 4 and 12 months of age...
March 31, 2018: Pediatric Infectious Disease Journal
keyword
keyword
61786
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"