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https://www.readbyqxmd.com/read/28822346/comparative-study-of-single-combination-use-of-huang-lian-jie-du-decoction-and-berberine-on-their-protection-on-sepsis-induced-acute-liver-injury-by-nmr-metabolic-profiling
#1
Yan Lv, Junsong Wang, Dingqiao Xu, Shanting Liao, Pei Li, Qian Zhang, Minghua Yang, Lingyi Kong
Sepsis is a serious clinical disease with a high mortality rate all around the world. Liver organ dysfunction is an important sign for the severity and outcome of sepsis in patients. In this study, (1)H NMR-based metabolomics approach and biochemical assays were applied to investigate the metabolic profiling for cecal ligation and puncture (CLP) induced acute liver injury, the therapeutical effect of single/combination use of Huang-Lian-Jie-Du decoction (HLJDD) and berberine, and the interaction of them. Metabolomics analysis revealed significant perturbations in livers of septic rats, which could be ameliorated by HLJDD, berberine and their combination treatment...
August 1, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28821119/tailoring-of-temperature-and-ph-responsive-cotton-fabric-with-antimicrobial-activity-effect-of-the-concentration-of-a-bio-barrier-forming-agent
#2
Danaja Štular, Ivan Jerman, Barbara Simončič, Brigita Tomšič
A stimuli-responsive cotton fabric was designed using temperature and pH-responsive poly-N-isopropylacrylamide (poly-NiPAAm) and chitosan (PNCS) microgel as a carrier of antimicrobially active 3-(trimethoxysilyl)-propyldimethyloctadecyl ammonium chloride (Si-QAC), which forms a bio-barrier on the fibre surface. The influence of Si-QAC on the moisture management and thermoregulation abilities of the PNCS microgel was investigated. Using a pad-dry cure method, Si-QAC was applied to a 100% cotton fabric model in concentrations ranging from 0...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821050/clean-approach-to-synthesis-of-graphene-like-cufe2o4-polysaccharide-resin-nanohybrid-bifunctional-compound-for-dye-adsorption-and-bacterial-capturing
#3
Mostafa Hossein Beyki, Sarina Ehteshamzadeh Ganjbakhsh, Sara Minaeian, Farzaneh Shemirani
Focus of this research is on employment of a green route to prepare magnetic CuFe2O4@polysaccharide resin for environmental remediation purpose. The method is including solvent free solid state synthesis of copper ferrite nanoparticles by combustion route using cellulose as fuel. Then polysaccharide resin as well as its magnetic composite was prepared by using glucose, citric acid and copper ferrite as solid raw materials. Characterization study using FESEM and TEM images showed that as synthesized resin possesses graphene like structure as ferrite nanoparticles are dispersed in the matrice of resin...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821032/using-oxidized-amylose-as-carrier-of-linalool-for-the-development-of-antibacterial-wound-dressing
#4
Yongbo Lyu, He Ren, Mengchao Yu, Xinying Li, Defu Li, Changdao Mu
This study aimed to prepare antibacterial wound dressings based on collagen and linalool/oxidized amylose inclusion complex. Encapsulation with oxidized amylose was used as an effective way to introduce linalool into collagen matrix. Our results showed that the content of linalool in the composite dressings was efficiently increased thanks to the solubilization effect of oxidized amyloses. The developed composite dressings possessed porous structure. They had abilities to keep the wound in moist environment and meanwhile prevent the excess exudates accumulation...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821030/preparation-and-characterization-of-a-photocatalytic-antibacterial-material-graphene-oxide-tio2-bacterial-cellulose-nanocomposite
#5
Ling-Pu Liu, Xiao-Ning Yang, Li Ye, Dong-Dong Xue, Miao Liu, Shi-Ru Jia, Ying Hou, Li-Qiang Chu, Cheng Zhong
In this study, bacterial cellulose (BC) was used as a matrix to synthesize graphene oxide/Titanium dioxide (GOTiO2)-based hybrid materials. It was indicated by X-ray diffraction and selected area electron diffraction that the crystal structure of GOTiO2 was a mixed phase containing anatase and rutile. TiO2 nanoparticles were of 10-30nm diameters and densely anchored on graphene oxide sheets. Superior photocatalytic performance of the GOTiO2 was achieved under near UV excitation. The photocatalytic efficiency was optimized through controlling an appropriate calcined temperature...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821027/preparation-characterization-and-antibacterial-activity-of-oxidized-%C3%AE%C2%BA-carrageenan
#6
Mingjin Zhu, Liming Ge, Yongbo Lyu, Yaxin Zi, Xinying Li, Defu Li, Changdao Mu
The oxidized κ-carrageenans with different oxidation levels were prepared through the hydrogen peroxide and copper sulfate redox system. The oxidation level of oxidized κ-carrageenan was successfully controlled by adjusting the dosage of hydrogen peroxide. The results showed that the microtopography of oxidized κ-carrageenan changed from rough granules to smooth flakes, mainly resulting from the easily melting property of oxidized κ-carrageenan induced by introduced carboxyl and aldehyde groups. Especially, the antibacterial activity of oxidized κ-carrageenans against Gram-positive bacteria (Staphylococcus aureus and Listeria monocytogenes) and Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa) was systematically investigated...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28820533/actinomycetes-still-a-source-of-novel-antibiotics
#7
REVIEW
Olga Genilloud
Covering: 2006 to 2017Actinomycetes have been, for decades, one of the most important sources for the discovery of new antibiotics with an important number of drugs and analogs successfully introduced in the market and still used today in clinical practice. The intensive antibacterial discovery effort that generated the large number of highly potent broad-spectrum antibiotics, has seen a dramatic decline in the large pharma industry in the last two decades resulting in a lack of new classes of antibiotics with novel mechanisms of action reaching the clinic...
August 18, 2017: Natural Product Reports
https://www.readbyqxmd.com/read/28820482/in-situ-synthesis-of-silver-nanoparticles-on-the-polyelectrolyte-coated-sericin-pva-film-for-enhanced-antibacterial-application
#8
Rui Cai, Gang Tao, Huawei He, Pengchao Guo, Meirong Yang, Chaoxiang Ding, Hua Zuo, Lingyan Wang, Ping Zhao, Yejing Wang
To develop silk sericin (SS) as a potential antibacterial biomaterial, a novel composite of polyelectrolyte multilayers (PEMs) coated sericin/poly(vinyl alcohol) (SS/PVA) film modified with silver nanoparticles (AgNPs) has been developed using a layer-by-layer assembly technique and ultraviolet-assisted AgNPs synthesis method. Ag ions were enriched by PEMs via the electrostatic attraction between Ag ions and PEMs, and then reduced to AgNPs in situ with the assistance of ultraviolet irradiation. PEMs facilitated the high-density growth of AgNPs and protected the synthesized AgNPs due to the formation of a 3D matrix, and thus endowed SS/PVA film with highly effective and durable antibacterial activity...
August 18, 2017: Materials
https://www.readbyqxmd.com/read/28820111/description-of-actinokineospora-acnipugnans-sp-nov-an-actinomycete-isolated-from-soil-showing-potential-uses-in-cosmetics
#9
Ram Hari Dahal, Dong Seop Shim, Jaisoo Kim
During isolation of soil bacteria having antibacterial functions, an aerobic, Gram-stain-positive, oxidase-negative, catalase-positive bacterium, designated strain R434T, was isolated. Strain R434T showed antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis and significant enzyme-inhibitory capability. The diagnostic diamino acid of the cell-wall peptidoglycan was meso-diaminopimelic acid, and the whole-cell sugars were galactose, arabinose and glucose. Phylogenetic analysis based on the 16S rRNA gene sequence revealed that strain R434T formed a lineage within the family Pseudonocardiaceae...
August 18, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28819978/nanostructured-fibrous-membranes-with-rose-spike-like-architecture
#10
Amir Nasajpour, Serena Mandla, Sindu Shree, Ebrahim Mostafavi, Roholah Sharifi, Akbar Khalilpour, Saghi Saghazadeh, Shabir Hassan, Michael J Mitchell, Jeroen Leijten, Xu Hou, Alireza Moshaverinia, Nasim Annabi, Rainer Adelung, Yogendra Kumar Mishra, SuRyon Shin, Ali Tamayol, Ali Khademhosseini
Nanoparticles have been used for engineering composite materials to improve the intrinsic properties and/or add functionalities to pristine polymers. The majority of the studies have focused on the incorporation of spherical nanoparticles within the composite fibers. Herein, we incorporate anisotropic branched-shaped zinc oxide (ZnO) nanoparticles into fibrous scaffolds fabricated by electrospinning. The addition of the branched particles resulted in their protrusion from fibers, mimicking the architecture of a rose-stem...
August 18, 2017: Nano Letters
https://www.readbyqxmd.com/read/28819794/in-vitro-selection-and-identification-of-potential-probiotics-isolated-from-the-gastrointestinal-tract-of-nile-tilapia-oreochromis-niloticus
#11
Rasha M Reda, Khaled M Selim, Hassanin M El-Sayed, M A El-Hady
Fish gut bacteria can be used as probiotics for aquaculture. The aim of this study is to screen and identify beneficial probiotic bacteria from the gut of Nile tilapia, Oreochromis niloticus. Nine out of one hundred thirty-five isolates were non-pathogenic through intraperitoneal injection and had antibacterial activities with at least a strain from the five isolated fish pathogens, Aeromonas sobria, Aeromonas hydrophila, Pseudomonas aeruginosa, Pseudomonas putida, and Staphylococcus aureus. Further tests showed that such isolates can survive in the presence of high bile concentration (10%) and at different acidic pH values...
August 17, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/28818729/characterization-of-citrus-pectin-films-integrated-with-clove-bud-essential-oil-physical-thermal-barrier-antioxidant-and-antibacterial-properties
#12
Tanzeela Nisar, Zi-Chao Wang, Xi Yang, You Tian, Muneeb Iqbal, Yurong Guo
The increasing demand for bio-based materials to be used in food packaging has stimulated the development of novel, environmentally-friendly edible films. Antimicrobial films were developed by incorporating different levels of clove bud essential oil (0.5%, 1.0%, and 1.5%) into the citrus pectin in order to modify the functional properties of the films. Fourier-transform infrared spectroscopy (FTIR), differential scanning calorimetry analysis (DSC) and X-ray diffraction (XRD) were performed, together with the determination of physical, optical, mechanical, antioxidant and antimicrobial properties of pectin emulsified films...
August 14, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28818719/green-approach-for-one-pot-synthesis-of-silver-nanorod-using-cellulose-nanocrystal-and-their-cytotoxicity-and-antibacterial-assessment
#13
Th I Shaheen, Amr Fouda
Herein, this research addresses an innovative approach for one-pot synthesis of highly stabilized silver nanorods in powder form at concentration as high as feasible to be proposed in large-scale production via cellulose nanocrystals (CNC). For the first time, CNC without any surface modification in the presence of alkali is acting as both reducing and stabilizing agent for assembling of Ag nanorods. Extraction of CNC from cotton is carried out as per to acid hydrolysis technique. Thorough assessments of Ag nanorods formation, structural and morphological characteristics of Ag nanorods were investigated by making use of UV-vis spectroscopy, TEM, DLS, AFM and X-ray diffraction(XRD) analysis...
August 14, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28816369/in-vitro-study-of-five-herbs-used-against-microbial-infections-in-burundi
#14
Jérémie Ngezahayo, Sofia Oliveira Ribeiro, Véronique Fontaine, Léonard Hari, Caroline Stévigny, Pierre Duez
The emergence of antimicrobial resistant infectious diseases remains a major threat to worldwide public health, in developed and in developing countries. Therefore, new antimicrobial agents acting by new mechanisms of action are urgently needed. As plants used in traditional medicine may help to overcome these problems, Justicia subsessilis, Platostoma rotundifolium, Pavetta ternifolia, Stomatanthes africanus, and Virectaria major (plants highly cited to be used against microbial infections in traditional Burundian medicine) were studied to assess their traditional use efficacy...
August 17, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28815637/synergistic-antibacterial-and-antibiofilm-efficacy-of-nisin-in-combination-with-p-coumaric-acid-against-foodborne-bacteria-bacillus-cereus-and-salmonella-typhimurium
#15
Anwesa Bag, Rabi Ranjan Chattopadhyay
The aim of the study was to evaluate possible antibacterial and antibiofilm efficacy of a bacteriocin, nisin with two essential oil components linalool and p-coumaric acid in combination against foodborne bacteria Bacillus cereus and Salmonella typhimurium. Their inhibition effects on planktonic cells and pre-formed biofilms were evaluated using microbroth dilution and checkerboard titration methods. Nisin/ p-coumaric acid combination showed synergistic effects against planktonic cells of both the studied bacteria whereas nisin/ linalool combination showed synergistic activity against B...
August 16, 2017: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/28815210/lpxk-is-essential-for-growth-of-acinetobacter-baumannii-atcc-19606-relationship-to-toxic-accumulation-of-lipid-a-pathway-intermediates
#16
Jun-Rong Wei, Daryl L Richie, Mina Mostafavi, Louis E Metzger, Christopher M Rath, William S Sawyer, Kenneth T Takeoka, Charles R Dean
Acinetobacter baumannii ATCC 19606 can grow without lipid A, the major component of lipooligosaccharide. However, we previously reported that depletion of LpxH (the fourth enzyme in the lipid A biosynthetic pathway) prevented growth of this strain due to toxic accumulation of lipid A pathway intermediates. Here, we explored whether a similar phenomenon occurred with depletion of LpxK, a kinase that phosphorylates disaccharide 1-monophosphate (DSMP) at the 4' position to yield lipid IVA. An A. baumannii ATCC 19606 derivative with LpxK expression under the control of an isopropyl β-d-1-thiogalactopyranoside (IPTG)-regulated expression system failed to grow without induction, indicating that LpxK is essential for growth...
July 2017: MSphere
https://www.readbyqxmd.com/read/28814863/gentamicin-coating-of-nanotubular-anodized-titanium-implant-reduces-implant-related-osteomyelitis-and-enhances-bone-biocompatibility-in-rabbits
#17
Denghui Liu, Chongru He, Zhongtang Liu, Weidong Xu
Titanium and titanium alloy are widely used as orthopedic implants for their favorable mechanical properties and satisfactory biocompatibility. The aim of the present study was to investigate the antibacterial effect and bone cell biocompatibility of a novel implant made with nanotubular anodized titanium coated with gentamicin (NTATi-G) through in vivo study in rabbits. The animals were divided into four groups, each receiving different kinds of implants, that is, NTATi-G, titanium coated with gentamicin (Ti-G), nanotubular anodized titanium uncoated with gentamicin (NTATi) and titanium uncoated with gentamicin (Ti)...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28814799/on-mechanism-behind-uv-a-light-enhanced-antibacterial-activity-of-gallic-acid-and-propyl-gallate-against-escherichia-coli-o157-h7
#18
Qingyang Wang, Erick Falcao de Oliveira, Solmaz Alborzi, Luis J Bastarrachea, Rohan V Tikekar
Possible mechanisms behind the enhanced antimicrobial activity of gallic acid (GA) and its ester propyl gallate (PG) in the presence of UV-A light against Escherichia coli O157:H7 were investigated. GA by itself is a mild antimicrobial and has a pro-oxidant ability. We found that the presence of UV-A light increases the uptake of GA by the bacteria. Once GA is internalized, the interaction between GA and UV-A induces intracellular ROS formation, leading to oxidative damage. Concurrently, GA + UV-A also inhibits the activity of superoxide dismutase (SOD), magnifying the imbalance of redox status of E...
August 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28814165/ag-implantation-induces-mechanical-properties-cell-adhesion-and-antibacterial-effects-of-tin-ag-multilayers-in-vitro
#19
Xiuhua Sun, Huanhuan Gong, Dejun Li, Lei Dong, Mengli Zhao, Rongxin Wan, Hanqing Gu
AIM: This study aims to investigate the effect of Ag(+) implantation dose on the structure, hardness, adhesion strength, friction resistance, cell adhesion and antibacterial effects of TiN/Ag multilayers. METHODS: Nanoscale TiN/Ag multilayers were deposited on Ti-6Al-4V substrates using multiarc ion plating. The multilayers were then implanted by Ag ions. RESULTS: A distinct multilayer structure and large titanium nitride grains with better (111) crystallinity were proved...
August 17, 2017: Nanomedicine
https://www.readbyqxmd.com/read/28813096/cytotoxicity-and-bacterial-membrane-destabilization-induced-by-annona-squamosa-l-extracts
#20
Nícolas C C Pinto, Jucélia B Silva, Laura M Menegati, Maria Clara M R Guedes, Lucas B Marques, Thiago P DA Silva, Rossana C N DE Melo, Elaine M DE Souza-Fagundes, Marcos J Salvador, Elita Scio, Rodrigo L Fabri
This study aimed to further investigate the cytotoxicity against tumor cell lines and several bacterial strains of Annona squamosa and its mode of action. Methanol extracts of A. squamosa leaves (ASL) and seeds (ASS) were used. ASL showed significant antibacterial activity against S. aureus, K. pneumoniae and E. faecalis with MIC values of 78, 78 and 39 µg/mL respectively. Moreover, ASL exhibited significant biofilm disruption, rapid time dependent kinetics of bacterial killing, increased membrane permeability and significantly reduced the cell numbers and viability...
August 14, 2017: Anais da Academia Brasileira de Ciências
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