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https://www.readbyqxmd.com/read/28989243/a-comprehensive-review-on-rasam-a-south-indian-traditional-functional-food
#1
REVIEW
Agilandeswari Devarajan, M K Mohanmarugaraja
The view that food can have an expanded role that goes well beyond providing a source of nutrients truly applies to traditional functional foods. The systematic consumption of such traditional functional food provides an excellent preventive measure to ward off many diseases. Rasam, a soup of spices, is a traditional South Indian food. It is traditionally prepared using tamarind juice as a base, with the addition of Indian sesame oil, turmeric, tomato, chili pepper, pepper, garlic, cumin, curry leaves, mustard, coriander, asafoetida, sea salt, and water...
July 2017: Pharmacognosy Reviews
https://www.readbyqxmd.com/read/28959668/farnesiferol-c-induces-cell-cycle-arrest-and-apoptosis-mediated-by-oxidative-stress-in-mcf-7-cell-line
#2
Davoud Hasanzadeh, Majid Mahdavi, Gholamreza Dehghan, Hojjatollah Nozad Charoudeh
Farnesiferol C is one of the major compounds, isolated from Ferula asafoetida (a type of coumarins) and used for cancer treatment as a folk remedy. Treatment of many cancers depends on oxidative stress situation. In this study, we sought the hypothesis that oxidative stress induced by Farnesiferol C contribute to anticancer property and induce apoptosis in MCF-7, human breast cancer cell line. We investigated the effect of Farnesiferol C on oxidative stress by measurement of some enzymes activity including catalase (CAT), superoxide dismutase (SOD), malondialdehyde (MDA), as well as some parameters such as total thiol and ROS levels...
2017: Toxicology Reports
https://www.readbyqxmd.com/read/28959663/beyond-the-flavor-a-green-formulation-of-ferula-asafoetida-oleo-gum-resin-with-fenugreek-dietary-fibre-and-its-gut-health-potential
#3
Liju Vijayasteltar, I J Jismy, Ashil Joseph, Balu Maliakel, Ramadasan Kuttan, Krishnakumar I M
Albeit the fact that asafotida is a popular kitchen spice and Indian folklore medicine for gut disorders, its consumption at physiologically relevant dosage is greatly challenged by the unpleasant flavor characteristics. Herein we report a green approach to derive stable powder formulations of asafoetida gum with minimized taste and odor suitable for dietary applications and gut health-related disorders. Employing a water based ultrasound mediated gel-phase dispersion of asafoetida gum on fenugreek derived soluble galactomannan fibre matrix...
2017: Toxicology Reports
https://www.readbyqxmd.com/read/28900317/evaluation-of-cytotoxicity-effects-of-oleo-gum-resin-and-its-essential-oil-of-ferula-assa-foetida-and-ferulic-acid-on-4t1-breast-cancer-cells
#4
Seyyed Majid Bagheri, Amir Abdian Asl, Ali Shams, Seyyed Ali Mirghanizadeh-Bafghi, Zeynab Hafizibarjin
BACKGROUND: Cancer causes significant morbidity and mortality and is a major public health problem worldwide. Breast cancer is a leading cause of cancer-associated mortality in women, and the incidence is also on the rise in the entire world. Medicinal plants have been an important source of several clinically useful anticancer agents. AIM: In this study, we studied the growth inhibitory effect of asafoetida and its essential oil and ferulic acid on antitumor activity using mouse breast cancer cell line...
April 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/28887965/preparation-characterization-and-anti-colitis-activity-of-curcumin-asafoetida-complex-encapsulated-in-turmeric-nanofiber
#5
Sreeraj Gopi, Augustine Amalraj, Shintu Jude, Karthik Varma, T R Sreeraj, Józef T Haponiuk, Sabu Thomas
Ulcerative colitis (UC) is a main form of inflammatory bowel disease (IBD). Asafoetida (ASF) and turmeric have traditionally been used for the treatment of various inflammatory diseases, including UC, because ASF is rich in sulfur compounds and turmeric contains curcumin (CUR). Turmeric nanofiber (TNF), the modified cell wall component of turmeric is considered to play important role in the human diet, health and can be used as a carrier agent to encapsulate bioactive components. A novel gut health product (GHP) was formulated by encapsulation of ASF and CUR complex onto TNF...
December 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28725631/biological-activities-and-medicinal-properties-of-asafoetida-a-review
#6
REVIEW
Augustine Amalraj, Sreeraj Gopi
Ferula asafoetida Linn. is a main source of asafoetida, a strong, tenacious and sulfurous odor, and oleo-gum resin of medicinal and nutritional importance. Asafoetida has been consumed as a spice and a folk medicine for centuries. Recent studies have shown several promising activities particularly relaxant, neuroprotective, memory enhancing, digestive enzyme, antioxidant, antispasmodic, hypotensive, hepatoprotective, antimicrobial, anticarcinogenic, anticancer, anticytotoxicity, antiobesity, anthelmintic and antagonistic effect...
July 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/28690055/antitumor-effect-of-ferula-assa-foetida-oleo-gum-resin-against-breast-cancer-induced-by-4t1-cells-in-balb-c-mice
#7
Seyyed Majid Bagheri, Amir Abdian-Asl, Mahin Taheri Moghadam, Maryam Yadegari, Aghdas Mirjalili, Fatemeh Zare-Mohazabieh, Haniyeh Momeni
BACKGROUND: Ferula assa foetida commonly consumed as a healthy beverage has been demonstrated to have various biological activities, including antioxidation, anti-obesity and anti-cancer. OBJECTIVE: Our study aims to investigate the antitumor effect of asafoetida in vivo using mouse mammary carcinoma 4T1 cells. MATERIALS AND METHODS: In the study, female BALB/c mice were divided into two groups (n = 6), which were control (untreated) and other group of mice with breast cancer treated with 100 mg/kg of asafoetida, respectively, by oral gavage...
July 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28487192/a-facile-approach-to-the-isolation-of-proteins-in-ferula-asafoetida-and-their-enzyme-stabilizing-anti-microbial-and-anti-oxidant-activity
#8
Sanjana Chandran, Meenakumari Sakthivel, Munusamy Thirumavalavan, Jagadeshwar Reddy Thota, Vairamani Mariappanadar, Pachaiappan Raman
The objective of the present study was to identify the proteome pattern, isolate and study the functions of selective proteins from Ferula asafoetida root exudate using chromatographic techniques. The root exudate proteins were fractionated using ion-exchange and gel filtration chromatography. A range of bioactive protein fractions were then separated in sufficient quantity which is the focus of this study. Based on studies, here we report three main proteins with molecular weights 14kDa, 27kDa, and 39kDa. The biological and pharmacological activities of both purified and unpurified proteins obtained were extensively studied to understand their significance...
September 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28289382/the-hydrogen-sulfide-releasing-molecule-acetyl-deacylasadisulfide-inhibits-metastatic-melanoma
#9
Paola De Cicco, Elisabetta Panza, Chiara Armogida, Giuseppe Ercolano, Orazio Taglialatela-Scafati, Yalda Shokoohinia, Rosa Camerlingo, Giuseppe Pirozzi, Vincenzo Calderone, Giuseppe Cirino, Angela Ianaro
Melanoma is the most common form of skin cancer. Given its high mortality, the interest in the search of preventive measures, such as dietary factors, is growing significantly. In this study we tested, in vitro and in vivo, the potential anti-cancer effect of the acetyl deacylasadisulfide (ADA), a vinyl disulfide compound, isolated and purified from asafoetida a foul-smelling oleo gum-resin of dietary and medicinal relevance. ADA markedly suppressed proliferation of human melanoma cell lines by inducing apoptosis...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27942173/effect-of-ferula-assa-foetida-oleo-gum-resin-on-renal-function-in-normal-wistar-rats
#10
S M Bagheri, H Mohammadsadeghi, M H Dashti-R, S M M Mousavian, Z A Aghaei
In traditional Iranian medicine, asafoetida, an oleo-gum-resin obtained from the roots of Ferula assa-foetida, has been prescribed as a diuretic. This study was undertaken to investigate the diuretic effect of asafoetida in normal rats. Asafoetida was administered orally at the doses of 25 and 50 mg/kg and furosemide (10 mg/kg, intraperitoneal) was used as positive control. The diuretic effect was evaluated by measuring urine volume and sodium, potassium, urea, and creatinine content in urine and serum. Urine volume, excretion of sodium, and potassium were significantly increased by asafoetida as compared to the control group...
November 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27540324/possible-mechanisms-for-functional-antagonistic-effect-of-ferula-assafoetida-on-muscarinic-receptors-in-tracheal-smooth-muscle
#11
Majid Kiyanmehr, Mohammad Hossein Boskabady, Mohammad Reza Khazdair, Milad Hashemzehi
BACKGROUND: The contribution of histamine (H1) receptors inhibitory and/or β-adrenoceptors stimulatory mechanisms in the relaxant property of Ferula assa-foetida. (F. asafoetida) was examined in the present study. METHODS: We evaluated the effect of three concentrations of F. asafoetida extract (2.5, 5, and 10 mg/mL), a muscarinic receptors antagonist, and saline on methacholine concentration-response curve in tracheal smooth muscles incubated with β-adrenergic and histamine (H1) (group 1), and only β-adrenergic (group 2) receptors antagonists...
January 2016: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/27104031/nematicidal-and-antimicrobial-activities-of-methanol-extracts-of-17-plants-of-importance-in-ethnopharmacology-obtained-from-the-arabian-peninsula
#12
Adel Al-Marby, Chukwunonso Ecc Ejike, Muhammad Jawad Nasim, Nasser A Awadh-Ali, Rwaida A Al-Badani, Ghanem Ma Alghamdi, Claus Jacob
AIM/BACKGROUND: The development of resistance to synthetic drugs by target organisms is a major challenge facing medicine, yet locked within plants are phytochemicals used in herbal medicine (especially in the Arabian Peninsula) that may find application in this regard. In pursuit of unlocking these "hidden treasures," the methanol extracts of leaves, aerial parts, fruits, and resins of 17 plants used in the Arabian Peninsula were screened for antimicrobial activities. MATERIALS AND METHODS: The nematicidal, antibacterial, and antifungal activities were determined using appropriate assays...
March 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/26963574/sulphur-containing-compounds-in-the-essential-oil-of-ferula-alliacea-roots-and-their-mass-spectral-fragmentation-patterns
#13
Jamal Kasaian, Javad Asili, Mehrdad Iranshahi
Context GC-MS analysis is the best way to characterize volatile sulphur-containing compounds. Ferula (Apiaceae) is a genus of perennial herbs. Due to the occurrence of essential oils or oleoresins in the Ferula species, these plants usually possess strong aromatic scent. Terpenoid compounds were the most abundant constituents of Ferula oils, however, in some of Ferula species, the essential oils were dominated by volatile sulphur-containing compounds. Objectives Ferula alliacea Boiss. is considered one of the sources of the oleo-gum-resin asafoetida...
October 2016: Pharmaceutical Biology
https://www.readbyqxmd.com/read/26604552/effect-of-ferula-assa-foetida-oleo-gum-resin-on-spermatic-parameters-and-testicular-histopathology-in-male-wistar-rats
#14
Seyyed Majid Bagheri, Maryam Yadegari, Majid Porentezari, Aghdas Mirjalili, Ashraf Hasanpor, R Mohammad Hossein Dashti, Morteza Anvari
BACKGROUND: In Ayurveda and traditional medicines of different countries such as Iran, America and Brazil, asafoetida has been used as an aphrodisiac agent. OBJECTIVE: The present study was aimed to evaluate the effectiveness of asafoetida on spermatic and testicular parameters in treated rats. MATERIALS AND METHODS: A total of 30 male Wistar rats divided equally to five groups (one control and four test groups receiving 25, 50,100 and 200 mg/kg asafoetida respectively)...
July 2015: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/25985573/potential-inhibitory-effect-of-herbal-medicines-on-rat-hepatic-cytochrome-p450-2d-gene-expression-and-metabolic-activity
#15
F I Al-Jenoobi, H M Korashy, A Ahad, M Raish, A M Al-Mohizea, M A Alam, S A Al-Suwayeh, K M Alkharfy
The aim of current study was to investigate the effect of some commonly used medicinal herbs on the regulation of rat CYP2D gene expression and its metabolic activity. Wistar albino rats were treated for seven consecutive days with selected doses of five commonly used herbs (Trigonella foenum-graecum, Ferula asafoetida, Nigella sativa, Commiphora myrrha and Lepidium sativum). Thereafter, rat livers were harvested and CYP2D mRNA levels were determined by RT-PCR. The metabolic activity of CYP2D was performed on rat hepatic microsomes using dextromethorphan as specific substrate...
November 2014: Die Pharmazie
https://www.readbyqxmd.com/read/25788433/influence-of-asafoetida-on-prevention-and-treatment-of-memory-impairment-induced-by-d-galactose-and-nano2-in-mice
#16
Seyyed Majid Bagheri, Mohammad Hossein Dashti-R
In Iranian traditional medicine, asafoetida is introduced as a valuable remedy for nervous disorders. Dementia was induced by injection of d-galactose and NaNO2 for 60 consecutive days. Animals were divided into normal control (NC), dementia control (DC), dementia prophylactic (DP), and dementia treated (DT). The learning and memory functions were examined by 1-way active and passive avoidance tests, using a shuttle box device. Avoidance response in training tests and 1 and 3 weeks later was significantly increased in NC, DP, and DT groups compared to the DC group...
September 2015: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/25657791/antinociceptive-effect-of-ferula-assa-foetida-oleo-gum-resin-in-mice
#17
S M Bagheri, M H Dashti-R, A Morshedi
Ferula assa-foetida L. is distributed throughout central Asia and Mediterranean area and grows wildly in Iran and Afghanistan. Asafoetida is an oleo-gum-resin that is the exudates of the roots of Ferula assa-foetida and some other Ferula species. In Iranian traditional medicine, asafoetida is considered to be sedative, analgesic, carminative, antispasmodic, diuretic, antihelmintic, emmenagogue and expectorant. The aim of this study was to evaluate the antinociceptive effect of asafoetida in mice. The analgesic activity of asafoetida (25, 50 and 100 mg/kg) was compared with that of sodium diclofenac (30 mg/kg) or morphine sulfate (8 mg/kg) by using hot plate and acetic acid induced writhing tests...
May 2014: Research in Pharmaceutical Sciences
https://www.readbyqxmd.com/read/25564444/inhibition-of-quorum-sensing-in-pseudomonas-aeruginosa-by-two-herbal-essential-oils-from-apiaceae-family
#18
Ehsan Sepahi, Saeed Tarighi, Farajollah Shahriari Ahmadi, Abdolreza Bagheri
Ferula (Ferula asafoetida L.) and Dorema (Dorema aucheri Bioss.) both from Apiaceae family were tested for their anti-quorum sensing (QS) activity against Pseudomonas aeruginosa. Both essential oils exhibited anti-QS activity at 25 μg/ml of concenteration. At this concenteration Ferula fully abolished and Dorema reduced the violacein production by C. violaceum. Pyocyanin, pyoverdine, elastase and biofilm production were decreased in Ferula oil treatments. Dorema oil reduced pyoverdine and elastase production, while pyocyanin and biofilm production were not affacted...
February 2015: Journal of Microbiology / the Microbiological Society of Korea
https://www.readbyqxmd.com/read/25210675/anticonvulsant-effect-of-ferula-assa-foetida-oleo-gum-resin-on-chemical-and-amygdala-kindled-rats
#19
Seyyed Majid Bagheri, Mohamad Ebrahim Rezvani, Ali Reza Vahidi, Mansur Esmaili
BACKGROUND: In Iranian traditional medicine, Ferula assa-foetida oleo gum resin (asafoetida) have been used as anti-convulsant agents. AIMS: This study was designed to evaluate the anti-convulsant effect of asafoetida on chemical and amygdala -kindled rats. MATERIALS AND METHODS: In chemical model, rats received orally asafoetida at dose of 50 and 100 mg/kg 90 minutes prior to Pentylenetetrazol injection in dose of 35 mg/kg intraperitoneally (i...
August 2014: North American Journal of Medical Sciences
https://www.readbyqxmd.com/read/25099385/impact-of-herbal-medicines-like-nigella-sativa-trigonella-foenum-graecum-and-ferula-asafoetida-on-cytochrome-p450-2c11-gene-expression-in-rat-liver
#20
H M Korashy, F I Al-Jenoobi, M Raish, A Ahad, A M Al-Mohizea, M A Alam, K M Alkharfy, S A Al-Suwayeh
AIM: Combined use of herbs and drugs may result in clinically important herb-drug interactions. The majorities of these interactions are thought to be metabolism-based and involve induction or inhibition of cytochrome P450 (CYP). The current study was designed to investigate the effect of some commonly used herbs on rat CYP2C11 gene expression and metabolic activity. METHODS: Wistar rats were treated for 7 days with increasing doses of 3 herbs; Nigella sativa, Trigonella foenum-graecum, and Ferula asafoetida...
July 2015: Drug Research
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