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https://www.readbyqxmd.com/read/28330280/culturable-endophytic-bacteria-associated-with-medicinal-plant-ferula-songorica-molecular-phylogeny-distribution-and-screening-for-industrially-important-traits
#1
Yong-Hong Liu, Jian-Wei Guo, Nimaichand Salam, Li Li, Yong-Guang Zhang, Jian Han, Osama Abdalla Mohamad, Wen-Jun Li
Xinjiang, a region of high salinity and drought, is a host to many arid and semi-arid plants. Many of these plants including Ferula spp. have indigenous pharmaceutical histories. As many of the medicinal properties of plants are in tandem with the associated microorganisms residing within the plant tissues, it is advisable to explore the endophytic potential of such plants. In the present study, diversity of culturable bacteria isolated from medicinal plants Ferula songorica collected from Hebukesaier, Xinjiang were analyzed...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28270083/ferulenol-a-sesquiterpene-coumarin-induce-apoptosis-via-mitochondrial-dysregulation-in-lung-cancer-induced-by-benzo-a-pyrene-involvement-of-bcl2-protein
#2
Nesrine Lariche, Lahouel Mesbah, Lamia Benguedouar, Amar Zellagui
BACKGROUND: Ferulenol, a sesquiterpene coumarin, was extracted from "Ferula vesceritensis" and possesses pro-oxidative and anticancer effects in different types of cancer. OBJECTIVE: The objective of this study is to determine whether ferulenol has an anticancer effect by regulation the Bcl2 protein expression in lung cancer induced by benzo[a]pyrene in Wistar rats. METHODS: Rats in group 1 have received, intraperitoneally, olive oil and considered as controls, animals of group 2 were treated with 100 mg/kg of benzo[a]pyrene intraperitoneally in order to induce lung cancer for 24 weeks, the 3rd groups of rats received the ferulenol 50 mg/kg intraperitoneally after 24 weeks of administration of benzo[a]pyrene and the last group, the rats were treated with ferulenol alone 50 mg/kg...
February 13, 2017: Anti-cancer Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/28258152/chemical-composition-and-phagocyte-immunomodulatory-activity-of-ferula-iliensis-essential-oils
#3
Gulmira Özek, Igor A Schepetkin, Gulzhakhan A Utegenova, Liliya N Kirpotina, Spencer R Andrei, Temel Özek, Kemal Hüsnü Can Başer, Karime T Abidkulova, Svetlana V Kushnarenko, Andrei I Khlebnikov, Derek S Damron, Mark T Quinn
Essential oil extracts from Ferula iliensis have been used traditionally in Kazakhstan for treatment of inflammation and other illnesses. Because little is known about the biologic activity of these essential oils that contributes to their therapeutic properties, we analyzed their chemical composition and evaluated their phagocyte immunomodulatory activity. The main components of the extracted essential oils were (E)-propenyl sec-butyl disulfide (15.7-39.4%) and (Z)-propenyl sec-butyl disulfide (23.4-45.0%)...
March 3, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28249821/ethno-veterinary-practices-in-southern-india-for-captive-asian-elephant-ailments
#4
Samidurai Jayakumar, Selvarasu Sathiskumar, Nagarajan Baskaran, Radjasegarin Arumugam, Varadhrajan Vanitha
ETHENOPHARMACOLOGICAL RELEVANCE: India has a long tradition of practicing Ayurvedic medicine not only for human ailments, but also for the management of livestock in the form of ethno-veterinary practices. Asian elephant is a significant part of Indian culture, and ethno-veterinary practices have extended to manage and cure various ailments of Asian elephant in captivity. Much of this knowledge has been lost in the light of modern practices. AIM OF THE STUDY: This study is aimed at documenting the existing knowledge on ethno-veterinary medicines practiced by elephant keepers (mahouts) in Tamil Nadu and Puducherry...
February 26, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28242202/chemosensory-basis-of-larval-performance-of-papilio-hospiton-on-different-host-plants
#5
Giorgia Sollai, Maurizio Biolchini, Paolo Solari, Roberto Crnjar
Papilio hospiton Géné is an oligophagous species, endemic of the islands of Corsica and Sardinia, using various Apiaceae and Rutaceae as host plants, such as Ferula communis, Ferula arrigonii, Peucedanum paniculatum, Ruta lamarmorae and Pastinaca latifolia. We previously found that the lateral maxillary styloconic sensillum in the larva has two deterrent neurons, one phagostimulant and one salt specific, while the medial sensillum has two phagostimulant neurons, one deterrent and one salt specific. In this work we studied the sensitivity of gustatory receptor neurons (GRNs) to saps of F...
February 24, 2017: Journal of Insect Physiology
https://www.readbyqxmd.com/read/28210466/antimicrobial-effects-of-ferula-gummosa-boiss-gum-against-extended-spectrum-%C3%AE-lactamase-producing-acinetobacter-clinical-isolates
#6
Fatemeh Farid Afshar, Parvaneh Saffarian, Hamideh Mahmoodzadeh Hosseini, Fereshteh Sattarian, Mohsen Amin, Abbas Ali Imani Fooladi
BACKGROUND AND OBJECTIVES: Acinetobacter spp. are important causes of nosocomial infections. They possess various antibiotic resistance mechanisms including extended spectrum beta lactamases (ESBLs). The aim of this study was to determine antibiotic resistance profile of Acinetobacter clinical isolates especially among ESBL-producing strains and to investigate the antimicrobial effects of oleo-gum-resin extract and essential oil of Ferula gummosa Boiss. MATERIALS AND METHODS: 120 Acinetobacter strains were isolated from various clinical samples of hospitalized patients in Baqiyatallah hospital, Tehran during 2011-2012...
August 2016: Iranian Journal of Microbiology
https://www.readbyqxmd.com/read/28149496/pseudomoniasis-phytotherapy-a-review-on-most-important-iranian-medicinal-plants-effective-on-pseudomonas-aeruginosa
#7
REVIEW
Mahmoud Bahmani, Mahmoud Rafieian-Kopaei, Hassan Hassanzadazar, Morovat Taherikalani
BACKGROUND AND OBJECTIVES: Pseudomonas aeruginosa is a Gram-negative, aerobic bacterium found in water and soil. It is a normal flora in skin and gastrointestinal tract of human beings. P. aeruginosa as an opportunistic pathogen involved in nosocomial infections having multiple pathogenic factors and shows high rate of resistance to different antibiotics. The aim of this study was to identify the most important native medicinal plants of Iran effective on P. aeruginosa. MATERIALS AND METHODS: All required information was obtained by searching keywords such as P...
October 2016: Iranian Journal of Microbiology
https://www.readbyqxmd.com/read/28133517/phytochemistry-and-pharmacology-of-ferula-persica-boiss-a-review
#8
REVIEW
Zohreh Sattar, Mehrdad Iranshahi
Ferula persica, is the well-known species of the genus Ferula in Iran and has two varieties: persica and latisecta. They have both been extensively used in traditional medicine for a wide range of ailments. A great number of chemical compounds including sesquiterpene coumarins and polysulfides have been isolated from this plant. Fresh plant materials, crude extracts and isolated components of F. persica have shown a wide spectrum of pharmacological properties including anti-pigmentation in Serratia marcescens, cytotoxic, antibacterial, anti-fungal, anti-leishmanial, cancer chemopreventive, reversal of multi-drug resistance, anti-inflammatory and lipoxygenase inhibitory activity...
January 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28112016/the-anti-inflammatory-effect-of-sonchus-oleraceus-aqueous-extract-on-lipopolysaccharide-stimulated-raw-264-7-cells-and-mice
#9
Qi Li, Dan-Dan Dong, Qiu-Ping Huang, Jing Li, Yong-Yong Du, Bin Li, Huan-Qing Li, Ting Huyan
CONTEXT: Sonchus oleraceus L. (Asteraceae) (SO) is a dietary and traditional medicinal plant in China. However, its underlying mechanism of action as an anti-inflammatory agent is not known. OBJECTIVE: This study evaluates the anti-inflammatory activity of aqueous extract of SO. MATERIALS AND METHODS: The extract of SO was used to treat RAW 264.7 cells (in the working concentrations of 500, 250, 125, 62.5, 31.3 and 15.6 μg/mL) for 24 h...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/27975781/studies-on-the-chemical-stability-of-umbelliprenin-the-active-principle-of-ferula-spp
#10
V A Taddeo, F Epifano, P de Medina, S Fiorito, S Genovese
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27942357/the-effect-of-ferula-assa-foetida-l-and-carum-copticum-hydroalcoholic-extract-on-the-expression-levels-of-staphylococcus-aureus-genes-involved-in-quorum-sensing
#11
Najmeh Jomehpour, Gilda Eslami, Mohammad Bagher Khalili
BACKGROUND: Quorum sensing is a microbial cell-to-cell communication process. Quorum sensing bacteria produce and release extracellular messenger molecules called autoinducers. Gram-positive and Gram-negative, homoserine lactones, and oligopeptides are autoinducers used to communicate and regulate gene expression. OBJECTIVES: The goal of this study was to assess the impact of subinhibitory concentrations of Ferula assa-foetida l oleo-gum resin and Carum copticum fruit on the expression of tst and hld genes of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive S...
October 2016: Jundishapur Journal of Microbiology
https://www.readbyqxmd.com/read/27942173/effect-of-ferula-assa-foetida-oleo-gum-resin-on-renal-function-in-normal-wistar-rats
#12
S M Bagheri, H Mohammadsadeghi, M H Dashti-R, S M M Mousavian, Z A Aghaei
In traditional Iranian medicine, asafoetida, an oleo-gum-resin obtained from the roots of Ferula assa-foetida, has been prescribed as a diuretic. This study was undertaken to investigate the diuretic effect of asafoetida in normal rats. Asafoetida was administered orally at the doses of 25 and 50 mg/kg and furosemide (10 mg/kg, intraperitoneal) was used as positive control. The diuretic effect was evaluated by measuring urine volume and sodium, potassium, urea, and creatinine content in urine and serum. Urine volume, excretion of sodium, and potassium were significantly increased by asafoetida as compared to the control group...
November 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27886594/proposed-binding-mechanism-of-galbanic-acid-extracted-from-ferula-assa-foetida-to-dna
#13
F Ahmadi, Y Shokoohinia, Sh Javaheri, H Azizian
Recently, galbanic acid (GA), a sesquiterpenoid coumarin, has been introduced as an apoptotic and geno/cytotoxicity agent. In the present study, GA has been extracted from Ferula assa-foetida, a native medicinal plant in Iran, and characterized by (1)H NMR, mass spectroscopy. Additionally, spectroscopic studies have been performed in order to investigate its DNA-interaction mode. The electrochemical behavior of GA has been studied by cyclic voltammetry (CV) in various scan rates. In neutral media (pH=7.3) one irreversible cathodic peak was obtained at -1...
January 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/27881964/corrigendum-bioassay-guided-isolation-of-sesquiterpene-coumarins-from-ferula-narthex-bioss-a-new-anticancer-agent
#14
Mahboob Alam, Ajmal Khan, Abdul Wadood, Ayesha Khan, Shumaila Bashir, Akhtar Aman, Abdul Khaliq Jan, Abdur Rauf, Bashir Ahmad, Abdur Rahman Khan, Umar Farooq
[This corrects the article on p. 26 in vol. 7, PMID: 26909039.].
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27825341/essential-oils-in-vitro-activity-against-leishmania-amazonensis-cytotoxicity-and-chemical-composition
#15
Milene Aparecida Andrade, Clênia Dos Santos Azevedo, Flávia Nader Motta, Maria Lucília Dos Santos, Camila Lasse Silva, Jaime Martins de Santana, Izabela M D Bastos
BACKGROUND: The current chemotherapy for cutaneous leishmaniosis (CL) has a series of drug limitations such as toxic side effects, long duration, high costs and drug resistance, which requires the development of new drugs or effective alternatives to the CL treatment. Essential oils (EOs) are complex mixtures of secondary metabolites from various plants. It has been shown that several EOs, or their constituents, have inhibitory activity against protozoa. Thus, this study aims to evaluate the biological activity of different essential oils (EOs) on Leishmania (L...
November 8, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27792716/-efficacy-of-intestinal-splinting-in-hostile-abdomen-secondary-to-postoperative-flanges-in-pediatric-patients
#16
Eduardo Bracho-Blanchet, Mónica Langarica-Bulos, Roberto Dávila-Pérez, Emilio Fernández-Portilla, Cristian Zalles-Vidal, Jaime Nieto-Zermeño
Objetivo: Mostrar la eficacia de la FI para prolongar el tiempo libre de oclusión intestinal quirúrgica en niños con abdomen hostil secundario a bridas posquirúrgicas. Método: Análisis retrospectivo de FI por abdomen hostil de 2000 a 2011 y su seguimiento a largo plazo. Comparamos el tiempo libre de oclusión quirúrgica antes y después de la FI. Resultados: Se incluyeron 20 FI en 19 pacientes. Predominaron las causas congénitas, la mediana de edad en la cirugía fue de 6 meses, todos tenían cirugías previas con mediana de tres, y dos de ellas fueron por oclusión intestinal previa...
October 2016: Gaceta Médica de México
https://www.readbyqxmd.com/read/27703798/umbelliprenin-is-potentially-toxic-against-the-ht29-ct26-mcf-7-4t1-a172-and-gl26-cell-lines-potentially-harmful-against-bone-marrow-derived-stem-cells-and-non-toxic-against-peripheral-blood-mononuclear-cells
#17
Mohsen Rashidi, Seyed Ali Ziai, Taraneh Moini Zanjani, Ahad Khalilnezhad, Hamidreza Jamshidi, Davar Amani
BACKGROUND: Resistance to chemotherapy is a growing concern, thus natural anticancer agents are drawing the attention of many scientists and clinicians. One natural anticancer agent, umbelliprenin, is a coumarin produced by many species of Ferula. OBJECTIVES: We aimed to examine the inhibitory effect of umbelliprenin on human and mouse bone marrow-derived stem cells (BMDSCs), peripheral blood mononuclear cells (PBMCs), and different cancer cell lines. MATERIALS AND METHODS: In this in vitro experimental study, the HT29, CT26, MCF-7, 4T1, A172, and GL26 cancer cells and human and mouse BMDSCs and PBMCs were cultured in RPMI-1640 medium supplemented with 10% fetal bovine serum (FBS), incubated at 37°C for 24 hours in a 5% CO2 atmosphere, and then were treated with different concentrations of umbelliprenin dissolved in dimethyl sulfoxide (DMSO) (3, 6, 12, 25, 50, 100, and 200 µg/mL) for 24, 48, and 72 hours at 37°C...
July 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/27681714/antiprotozoal-and-antiglycation-activities-of-sesquiterpene-coumarins-from-ferula-narthex-exudate
#18
Adnan Amin, Emmy Tuenter, Paul Cos, Louis Maes, Vassiliki Exarchou, Sandra Apers, Luc Pieters
The exudate of Ferula narthex Boiss. (Apiaceae) is widely used in the Indian subcontinent as a spice and because of its health effects. Six sesquiterpene coumarins have been isolated from this exudate: feselol, ligupersin A, asacoumarin A, 8'-O-acetyl-asacoumarin A, 10'R-karatavacinol and 10'R-acetyl-karatavacinol. Based on its use in infectious and diabetic conditions, the isolated constituents were evaluated for antimicrobial and antiglycation activities. Some compounds showed activity against protozoal parasites, asacoumarin A being the most active one against Plasmodium falciparum K1 (IC50 1...
2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27638478/chemical-composition-and-in-vitro-evaluation-of-antimicrobial-antioxidant-and-antigerminative-properties-of-the-seed-oil-from-the-tunisian-endemic-ferula-tunetana-pomel-ex-batt
#19
Mansour Znati, Insaf Filali, Aymen Jabrane, Joseph Casanova, Jalloul Bouajila, Hichem Ben Jannet
Essential oil of the seeds from the endemic Tunisian plant Ferula tunetana Pomel ex Batt. was analyzed for its chemical composition and screened for its antimicrobial, antioxidant and antigerminative properties. The chemical composition of the isolated oil is reported for the first time. According to the GC/FID, GC/MS and (13) C-NMR analysis results; 18 compounds were identified accounting for 84.6% of the total oil. The chemical composition of this essential oil was characterized by the presence of a high proportion of monoterpene hydrocarbons (77...
January 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/27586050/modulation-of-human-neutrophil-responses-by-the-essential-oils-from-ferula-akitschkensis-and-their-constituents
#20
Igor A Schepetkin, Svetlana V Kushnarenko, Gulmira Özek, Liliya N Kirpotina, Pritam Sinharoy, Gulzhakhan A Utegenova, Karime T Abidkulova, Temel Özek, Kemal Hüsnü Can Başer, Anastasia R Kovrizhina, Andrei I Khlebnikov, Derek S Damron, Mark T Quinn
Essential oils were obtained by hydrodistillation of the umbels+seeds and stems of Ferula akitschkensis (FAEOu/s and FAEOstm, respectively) and analyzed by gas chromatography and gas chromatography-mass spectrometry. Fifty-two compounds were identified in FAEOu/s; the primary components were sabinene, α-pinene, β-pinene, terpinen-4-ol, eremophilene, and 2-himachalen-7-ol, whereas the primary components of FAEOstm were myristicin and geranylacetone. FAEOu/s, β-pinene, sabinene, γ-terpinene, geranylacetone, isobornyl acetate, and (E)-2-nonenal stimulated [Ca(2+)]i mobilization in human neutrophils, with the most potent being geranylacetone (EC50 = 7...
September 28, 2016: Journal of Agricultural and Food Chemistry
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