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https://www.readbyqxmd.com/read/28521374/phytochemistry-and-pharmacology-of-ferula-hermonis-boiss-a-review
#1
Zohreh Sattar, Mehrdad Iranshahi
Ferula hermonis, a well-known species of the genus Ferula found in Lebanon and Syria, has a brilliant history in traditional medicine as it has been used for the treatment of erectile dysfunction in men and menopausal disturbances in women. Thanks to modern pharmacological and clinical investigations, F. hermonis is a valuable medicinal and condimental plant that may be used for the treatment of impotence and diabetes, the prevention of osteoporosis, and possesses anti-microbial and anti-inflammatory properties...
May 18, 2017: Drug Research
https://www.readbyqxmd.com/read/28487192/a-facile-approach-to-the-isolation-of-proteins-in-ferula-asafoetida-and-their-enzyme-stabilizing-anti-microbial-and-anti-oxidant-activity
#2
Sanjana Chandran, Meenakumari Sakthivel, Munusamy Thirumavalavan, Jagadeshwar Reddy Thota, Vairamani Mariappanadar, Pachaiappan Raman
The objective of the present study was to identify the proteome pattern, isolate and study the functions of selective proteins from Ferula asafoetida root exudate using chromatographic techniques. The root exudate proteins were fractionated using ion-exchange and gel filtration chromatography. A range of bioactive protein fractions were then separated in sufficient quantity which is the focus of this study. Based on studies, here we report three main proteins with molecular weights 14kDa, 27kDa, and 39kDa. The biological and pharmacological activities of both purified and unpurified proteins obtained were extensively studied to understand their significance...
May 6, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28436508/purification-characterization-and-bioactivities-of-polysaccharides-from-pleurotus-ferulae
#3
Jinyu Li, Pengfei Yuan, Xinhui Wang, Adila Aipire, Minjing Li, Jie Yang, Hong Tao, Tianlei Ying, Changshuang Fu, Xianxian Wei, Fuchun Zhang, Jinyao Li
Pleurotus ferulae is an edible mushroom and has been used in Uygur medicine for a long time. In this study, we purified polysaccharides from P. ferulae (PFPS) and investigated its structural characteristics. We obtained a homogeneous PFPS with a molecular weight of around 1600 kDa and prominent characteristic polysaccharide groups, which mainly contained glucose (97%), followed by mannose and galactose (3%). Both (1)H and (13)C NMR spectra indicated that PFPS contained both α- and β-anomeric configurations...
May 24, 2017: Food & Function
https://www.readbyqxmd.com/read/28436319/in-vitro-antioxidant-and-in-vivo-hypolipidemic-effects-of-the-king-oyster-culinary-medicinal-mushroom-pleurotus-eryngii-var-ferulae-ddl01-agaricomycetes-in-rats-with-high-fat-diet-induced-fatty-liver-and-hyperlipidemia
#4
Jun-Hui Choi, Dae-Won Kim, Seung Kim, Sung-Jun Kim
We investigated the effect of the culinary-medicinal mushroom Pleurotus eryngii var. ferulae DDL01 on oxidative damage in the liver and brain and a high-fat/high-cholesterol-induced hyperlipidemic model. In in vitro studies, the water extracts of the fruiting bodies showed strong scavenging activities of DPPH (139.46 ± 3.2 μg) and hydroxyl (139.46 ± 3.2 μg) radicals. Moreover, the extracts showed Fe2+ chelating and reducing abilities, as well as a large amount of polyphenols and an inhibitory effect on lipid peroxidation in the liver and brain tissues...
2017: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/28423422/immunological-responses-of-sesamia-cretica-to-ferula-ovina-essential-oil
#5
Reza Sadeghi, Niloofar Hadizadeh Raeisi, Arsalan Jamshidnia
The current research was performed aiming to investigate the effects of Ferula ovina essential oil on the fourth instar larval hemogram of Sesamia cretica. Four main sorts of circulating hemocytes, including prohemocytes, plasmatocytes, granulocytes (GRs), and oenocytoides, were identified in the fourth instar larvae. Treatment of the larvae with the concentration of 1000 ppm of the essential oil led to an enhancement of the total hemocyte and GR count followed by a dose-dependent decrease at the concentrations of 2500 and 7000 ppm...
January 1, 2017: Journal of Insect Science
https://www.readbyqxmd.com/read/28330280/culturable-endophytic-bacteria-associated-with-medicinal-plant-ferula-songorica-molecular-phylogeny-distribution-and-screening-for-industrially-important-traits
#6
Yong-Hong Liu, Jian-Wei Guo, Nimaichand Salam, Li Li, Yong-Guang Zhang, Jian Han, Osama Abdalla Mohamad, Wen-Jun Li
Xinjiang, a region of high salinity and drought, is a host to many arid and semi-arid plants. Many of these plants including Ferula spp. have indigenous pharmaceutical histories. As many of the medicinal properties of plants are in tandem with the associated microorganisms residing within the plant tissues, it is advisable to explore the endophytic potential of such plants. In the present study, diversity of culturable bacteria isolated from medicinal plants Ferula songorica collected from Hebukesaier, Xinjiang were analyzed...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28270083/ferulenol-a-sesquiterpene-coumarin-induce-apoptosis-via-mitochondrial-dysregulation-in-lung-cancer-induced-by-benzo-a-pyrene-involvement-of-bcl2-protein
#7
Nesrine Lariche, Lahouel Mesbah, Lamia Benguedouar, Amar Zellagui
BACKGROUND: Ferulenol, a sesquiterpene coumarin, was extracted from "Ferula vesceritensis" and possesses pro-oxidative and anticancer effects in different types of cancer. OBJECTIVE: The objective of this study is to determine whether ferulenol has an anticancer effect by regulation the Bcl2 protein expression in lung cancer induced by benzo[a]pyrene in Wistar rats. METHODS: Rats in group 1 have received, intraperitoneally, olive oil and considered as controls, animals of group 2 were treated with 100 mg/kg of benzo[a]pyrene intraperitoneally in order to induce lung cancer for 24 weeks, the 3rd groups of rats received the ferulenol 50 mg/kg intraperitoneally after 24 weeks of administration of benzo[a]pyrene and the last group, the rats were treated with ferulenol alone 50 mg/kg...
February 13, 2017: Anti-cancer Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/28258152/chemical-composition-and-phagocyte-immunomodulatory-activity-of-ferula-iliensis-essential-oils
#8
Gulmira Özek, Igor A Schepetkin, Gulzhakhan A Utegenova, Liliya N Kirpotina, Spencer R Andrei, Temel Özek, Kemal Hüsnü Can Başer, Karime T Abidkulova, Svetlana V Kushnarenko, Andrei I Khlebnikov, Derek S Damron, Mark T Quinn
Essential oil extracts from Ferula iliensis have been used traditionally in Kazakhstan for treatment of inflammation and other illnesses. Because little is known about the biologic activity of these essential oils that contributes to their therapeutic properties, we analyzed their chemical composition and evaluated their phagocyte immunomodulatory activity. The main components of the extracted essential oils were (E)-propenyl sec-butyl disulfide (15.7-39.4%) and (Z)-propenyl sec-butyl disulfide (23.4-45.0%)...
March 3, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28249821/ethno-veterinary-practices-in-southern-india-for-captive-asian-elephant-ailments
#9
Samidurai Jayakumar, Selvarasu Sathiskumar, Nagarajan Baskaran, Radjasegarin Arumugam, Varadhrajan Vanitha
ETHENOPHARMACOLOGICAL RELEVANCE: India has a long tradition of practicing Ayurvedic medicine not only for human ailments, but also for the management of livestock in the form of ethno-veterinary practices. Asian elephant is a significant part of Indian culture, and ethno-veterinary practices have extended to manage and cure various ailments of Asian elephant in captivity. Much of this knowledge has been lost in the light of modern practices. AIM OF THE STUDY: This study is aimed at documenting the existing knowledge on ethno-veterinary medicines practiced by elephant keepers (mahouts) in Tamil Nadu and Puducherry...
February 26, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28242202/chemosensory-basis-of-larval-performance-of-papilio-hospiton-on-different-host-plants
#10
Giorgia Sollai, Maurizio Biolchini, Paolo Solari, Roberto Crnjar
Papilio hospiton Géné is an oligophagous species, endemic of the islands of Corsica and Sardinia, using various Apiaceae and Rutaceae as host plants, such as Ferula communis, Ferula arrigonii, Peucedanum paniculatum, Ruta lamarmorae and Pastinaca latifolia. We previously found that the lateral maxillary styloconic sensillum in the larva has two deterrent neurons, one phagostimulant and one salt specific, while the medial sensillum has two phagostimulant neurons, one deterrent and one salt specific. In this work we studied the sensitivity of gustatory receptor neurons (GRNs) to saps of F...
February 27, 2017: Journal of Insect Physiology
https://www.readbyqxmd.com/read/28210466/antimicrobial-effects-of-ferula-gummosa-boiss-gum-against-extended-spectrum-%C3%AE-lactamase-producing-acinetobacter-clinical-isolates
#11
Fatemeh Farid Afshar, Parvaneh Saffarian, Hamideh Mahmoodzadeh Hosseini, Fereshteh Sattarian, Mohsen Amin, Abbas Ali Imani Fooladi
BACKGROUND AND OBJECTIVES: Acinetobacter spp. are important causes of nosocomial infections. They possess various antibiotic resistance mechanisms including extended spectrum beta lactamases (ESBLs). The aim of this study was to determine antibiotic resistance profile of Acinetobacter clinical isolates especially among ESBL-producing strains and to investigate the antimicrobial effects of oleo-gum-resin extract and essential oil of Ferula gummosa Boiss. MATERIALS AND METHODS: 120 Acinetobacter strains were isolated from various clinical samples of hospitalized patients in Baqiyatallah hospital, Tehran during 2011-2012...
August 2016: Iranian Journal of Microbiology
https://www.readbyqxmd.com/read/28149496/pseudomoniasis-phytotherapy-a-review-on-most-important-iranian-medicinal-plants-effective-on-pseudomonas-aeruginosa
#12
REVIEW
Mahmoud Bahmani, Mahmoud Rafieian-Kopaei, Hassan Hassanzadazar, Morovat Taherikalani
BACKGROUND AND OBJECTIVES: Pseudomonas aeruginosa is a Gram-negative, aerobic bacterium found in water and soil. It is a normal flora in skin and gastrointestinal tract of human beings. P. aeruginosa as an opportunistic pathogen involved in nosocomial infections having multiple pathogenic factors and shows high rate of resistance to different antibiotics. The aim of this study was to identify the most important native medicinal plants of Iran effective on P. aeruginosa. MATERIALS AND METHODS: All required information was obtained by searching keywords such as P...
October 2016: Iranian Journal of Microbiology
https://www.readbyqxmd.com/read/28133517/phytochemistry-and-pharmacology-of-ferula-persica-boiss-a-review
#13
REVIEW
Zohreh Sattar, Mehrdad Iranshahi
Ferula persica, is the well-known species of the genus Ferula in Iran and has two varieties: persica and latisecta. They have both been extensively used in traditional medicine for a wide range of ailments. A great number of chemical compounds including sesquiterpene coumarins and polysulfides have been isolated from this plant. Fresh plant materials, crude extracts and isolated components of F. persica have shown a wide spectrum of pharmacological properties including anti-pigmentation in Serratia marcescens, cytotoxic, antibacterial, anti-fungal, anti-leishmanial, cancer chemopreventive, reversal of multi-drug resistance, anti-inflammatory and lipoxygenase inhibitory activity...
January 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28112016/the-anti-inflammatory-effect-of-sonchus-oleraceus-aqueous-extract-on-lipopolysaccharide-stimulated-raw-264-7-cells-and-mice
#14
Qi Li, Dan-Dan Dong, Qiu-Ping Huang, Jing Li, Yong-Yong Du, Bin Li, Huan-Qing Li, Ting Huyan
CONTEXT: Sonchus oleraceus L. (Asteraceae) (SO) is a dietary and traditional medicinal plant in China. However, its underlying mechanism of action as an anti-inflammatory agent is not known. OBJECTIVE: This study evaluates the anti-inflammatory activity of aqueous extract of SO. MATERIALS AND METHODS: The extract of SO was used to treat RAW 264.7 cells (in the working concentrations of 500, 250, 125, 62.5, 31.3 and 15.6 μg/mL) for 24 h...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/27975781/studies-on-the-chemical-stability-of-umbelliprenin-the-active-principle-of-ferula-spp
#15
V A Taddeo, F Epifano, P de Medina, S Fiorito, S Genovese
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27942357/the-effect-of-ferula-assa-foetida-l-and-carum-copticum-hydroalcoholic-extract-on-the-expression-levels-of-staphylococcus-aureus-genes-involved-in-quorum-sensing
#16
Najmeh Jomehpour, Gilda Eslami, Mohammad Bagher Khalili
BACKGROUND: Quorum sensing is a microbial cell-to-cell communication process. Quorum sensing bacteria produce and release extracellular messenger molecules called autoinducers. Gram-positive and Gram-negative, homoserine lactones, and oligopeptides are autoinducers used to communicate and regulate gene expression. OBJECTIVES: The goal of this study was to assess the impact of subinhibitory concentrations of Ferula assa-foetida l oleo-gum resin and Carum copticum fruit on the expression of tst and hld genes of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive S...
October 2016: Jundishapur Journal of Microbiology
https://www.readbyqxmd.com/read/27942173/effect-of-ferula-assa-foetida-oleo-gum-resin-on-renal-function-in-normal-wistar-rats
#17
S M Bagheri, H Mohammadsadeghi, M H Dashti-R, S M M Mousavian, Z A Aghaei
In traditional Iranian medicine, asafoetida, an oleo-gum-resin obtained from the roots of Ferula assa-foetida, has been prescribed as a diuretic. This study was undertaken to investigate the diuretic effect of asafoetida in normal rats. Asafoetida was administered orally at the doses of 25 and 50 mg/kg and furosemide (10 mg/kg, intraperitoneal) was used as positive control. The diuretic effect was evaluated by measuring urine volume and sodium, potassium, urea, and creatinine content in urine and serum. Urine volume, excretion of sodium, and potassium were significantly increased by asafoetida as compared to the control group...
November 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27886594/proposed-binding-mechanism-of-galbanic-acid-extracted-from-ferula-assa-foetida-to-dna
#18
F Ahmadi, Y Shokoohinia, Sh Javaheri, H Azizian
Recently, galbanic acid (GA), a sesquiterpenoid coumarin, has been introduced as an apoptotic and geno/cytotoxicity agent. In the present study, GA has been extracted from Ferula assa-foetida, a native medicinal plant in Iran, and characterized by (1)H NMR, mass spectroscopy. Additionally, spectroscopic studies have been performed in order to investigate its DNA-interaction mode. The electrochemical behavior of GA has been studied by cyclic voltammetry (CV) in various scan rates. In neutral media (pH=7.3) one irreversible cathodic peak was obtained at -1...
January 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/27881964/corrigendum-bioassay-guided-isolation-of-sesquiterpene-coumarins-from-ferula-narthex-bioss-a-new-anticancer-agent
#19
Mahboob Alam, Ajmal Khan, Abdul Wadood, Ayesha Khan, Shumaila Bashir, Akhtar Aman, Abdul Khaliq Jan, Abdur Rauf, Bashir Ahmad, Abdur Rahman Khan, Umar Farooq
[This corrects the article on p. 26 in vol. 7, PMID: 26909039.].
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27825341/essential-oils-in-vitro-activity-against-leishmania-amazonensis-cytotoxicity-and-chemical-composition
#20
Milene Aparecida Andrade, Clênia Dos Santos Azevedo, Flávia Nader Motta, Maria Lucília Dos Santos, Camila Lasse Silva, Jaime Martins de Santana, Izabela M D Bastos
BACKGROUND: The current chemotherapy for cutaneous leishmaniosis (CL) has a series of drug limitations such as toxic side effects, long duration, high costs and drug resistance, which requires the development of new drugs or effective alternatives to the CL treatment. Essential oils (EOs) are complex mixtures of secondary metabolites from various plants. It has been shown that several EOs, or their constituents, have inhibitory activity against protozoa. Thus, this study aims to evaluate the biological activity of different essential oils (EOs) on Leishmania (L...
November 8, 2016: BMC Complementary and Alternative Medicine
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