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https://www.readbyqxmd.com/read/29139613/nipple-sparing-mastectomy-as-treatment-for-patients-with-ductal-carcinoma-in%C3%A2-situ-a-10-year-follow-up-study
#1
Víctor Lago, Vincenzo Maisto, Julia Gimenez-Climent, Jose Vila, Carlos Vazquez, Rafael Estevan
The objective was to determine the 10-year oncological safety of nipple-sparing mastectomy (NSM) in patients diagnosed with ductal carcinoma in situ (DCIS). The use of NSM preserves the nipple-areola complex (NAC). As residual fibroglandular breast tissue can remain behind the spared NAC, its use for patient with breast cancer is controversial. The oncologic outcomes and complication rates after performing NSM compared to other techniques are still under debate and a concern when treating patients with breast cancer...
November 15, 2017: Breast Journal
https://www.readbyqxmd.com/read/29136496/association-between-pacifier-use-and-bottle-feeding-and-unfavorable-behaviors-during-breastfeeding
#2
Christyann L C Batista, Valdinar S Ribeiro, Maria do Desterro S B Nascimento, Vandilson P Rodrigues
OBJECTIVE: To investigate the association between pacifier use and bottle-feeding and unfavorable behaviors during breastfeeding. METHOD: A cross-sectional study was conducted with 427 babies/mothers. Socio-demographic, perinatal data, and information about the use of artificial nipples (pacifier and/or bottle) were collected through a questionnaire. The breastfeeding aspects regarding position, affectivity, sucking behavior, baby responses, and breast anatomy were evaluated through observation during breastfeeding...
November 11, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/29135512/cytokeratin-profile-of-basal-cell-carcinomas-according-to-the-degree-of-sun-exposure-and-to-the-anatomical-localization
#3
Ma Reyes García-de-la-Fuente, Maria Santacana, Joan Valls, Felip Vilardell, José Manuel Fernández Armenteros, Ramon Pujol, Eloi Gari, Josep Manel Casanova
Basal cell carcinoma (BCC) seems to originate from ultraviolet light-induced mutations involving the bulge or the outer sheath of the hair follicle cells. However, the etiopathogenic mechanisms involved in the development of these tumors in nonphotoexposed and in hairless areas remain unclear. The cytokeratin (CK) profile (including CK5/6, CK7, CK14, CK15, CK17, and CK19) from a series of different BCC subtypes developing in sun-exposed and non-sun-exposed areas, including hairless regions, was evaluated. The authors have observed that CK7 expression in BCC is associated with the anatomical localization of the tumor and its sun-exposition, but not with other factors such as histological subtype...
November 1, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29132771/-neonatal-herpes-epidemiology-clinical-manifestations-and-management-guidelines-for-clinical-practice-from-the-french-college-of-gynecologists-and-obstetricians-cngof
#4
L Renesme
OBJECTIVES: To describe the epidemiology of neonatal herpes and its risk factors, clinical and paraclinic manifestations, propose guidelines for a newborn at risk of neonatal herpes, describe treatment modalities, describe post-natal transmission and its prevention. METHODS: Bibliographic search from Medline, Cochrane Library databases and research of international clinical practice guidelines. RESULTS: Neonatal herpes is rare (about 20 cases per year in France) and mainly due to HSV 1 (level of evidence LE3)...
November 10, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29132559/oncoplastic-breast-reconstruction-should-all-patients-be-considered
#5
REVIEW
Mehran Habibi, Kristen P Broderick, Mohamad E Sebai, Lisa K Jacobs
Oncoplastic surgery of the tissue defect from partial mastectomy should be considered for all patients. It can result in in significant asymmetries from scar contraction, skin tethering, and alterations in the nipple areolar complex location. Indications, risks, and benefits are discussed. Optimal procedures are described, considering resected specimen volume, primary tumor location, tumor to breast size ratio, and the impact on the nipple areolar complex. Indications for plastic surgery consultation and joint surgery are discussed...
January 2018: Surgical Oncology Clinics of North America
https://www.readbyqxmd.com/read/29125335/a-review-of-mammographic-positioning-image-quality-criteria-for-the-craniocaudal-projection
#6
Rhonda-Joy I Sweeney, Sarah J Lewis, Peter Hogg, Mark F McEntee
Detection of breast cancer is reliant on optimal breast positioning and the production of quality images. Two projections, the mediolateral (MLO) and craniocaudal (CC), are routinely performed. Determination of successful positioning and inclusion of all breast tissue is achieved through meeting stated image quality criteria. For the CC view, current image quality criteria are inconsistent. Absence of reliable anatomical markers, other than the nipple, further contribute to difficulties in assessing the quality of CC views...
November 10, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29124373/-the-chignon-mastopexy-a-double-glandular-suspended-flaps-for-an-auto-augmentation-effect
#7
Bouraoui Kotti
BACKGROUND: Many mastopexy techniques have been described in the literature focusing on the new nipple areolar complex position and the breast deflation treatment, but only few of them detailed the glandular volume redistribution to avoid the use of implants. We describe a mastopexy procedure that brings the maximum of the volume to the central part of the breast. We compare the procedure to a "chignon" hair style way to vulgarize the technique and simplify its comprehension. METHODS: Breast volume is reshaped by the use of a vertical mastopexy and two deepithelized glandular flaps sutured for the first one to the pectoralis major fascia and for the second one to the contralateral flap...
November 9, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29119825/why-chinese-mothers-stop-breastfeeding-mothers-self-reported-reasons-for-stopping-during-the-first-six-months
#8
Ke Sun, Miaoxia Chen, Yuzhu Yin, Lingling Wu, Lingling Gao
The reasons why mothers in mainland China stop breastfeeding before their infants were six months old was investigated. Five hundred sixty-two mothers within two to three days after delivery in a hospital in Guangzhou, China, were followed up via telephone interview at one, four, and six months postpartum between January and August 2015 to assess their infant's feeding patterns and mother's reasons for breastfeeding cessation. Measures included the questionnaire about sociodemographic, psychosocial, and perinatal characteristics, the Breastfeeding Outcome Questionnaire and the Breastfeeding Self-efficacy Scale-Short Form...
September 2017: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://www.readbyqxmd.com/read/29116657/international-validation-of-the-european-organisation-for-research-and-treatment-of-cancer-qlq-brecon23-quality-of-life-questionnaire-for-women-undergoing-breast-reconstruction
#9
Z E Winters, M Afzal, C Rutherford, B Holzner, G Rumpold, R A da Costa Vieira, S Hartup, K Flitcroft, V Bjelic-Radisic, A Oberguggenburger, M Panouilleres, M Mani, G Catanuto, M Douek, J Kokan, P Sinai, M T King
BACKGROUND: The aim was to carry out phase 4 international field-testing of the European Organisation for Research and Treatment of Cancer (EORTC) breast reconstruction (BRECON) module. The primary objective was finalization of its scale structure. Secondary objectives were evaluation of its reliability, validity, responsiveness, acceptability and interpretability in patients with breast cancer undergoing mastectomy and reconstruction. METHODS: The EORTC module development guidelines were followed...
November 8, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/29114844/not-all-pacifiers-are-created-equal-a-mechanical-examination-of-pacifiers-and-their-influence-on-suck-patterning
#10
Emily Zimmerman, Jaclene Forlano, Andrew Gouldstone
Purpose: Many pacifier companies advertise that their product is the "best choice" to support proper sucking, feeding, and dental development; however, very little evidence exists to support these claims. As the primary differences across pacifiers are structural and mechanical, the goals of this study were to measure such properties of commercially available pacifiers and to examine how these properties alter suck patterning in healthy, full-term infants. Method: Seven commonly utilized pacifiers were mechanically tested for pull and compression stiffness levels and categorized into nipple shape types based on their aspect ratio...
November 8, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/29109950/paget-s-breast-disease-a-case-report-and-review-of-the-literature
#11
S Dubar, M Boukrid, Jean Bouquet de Joliniere, L Guillou, Quoc Duy Vo, A Major, N Ben Ali, F Khomsi, A Feki
Paget's disease of the breast is a rare cancer. This typical clinical case illustrates the different epidemiological, clinical, histological, therapeutic, and evolving aspects of the disease. We report a case of Paget's disease in a 43-year-old woman who presented eczema of the nipple. Mammography and ultrasounds did reveal a lesion in situ. The patient was scheduled for mastectomy and sentinel node biopsy. She had chosen a radical bilateral surgery. The histological diagnosis was Paget's disease of the breast with a carcinoma in situ...
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/29101435/polyurethane-foam-wound-dressing-technique-for-areola-skin-graft-stabilization-and-nipple-protection-after-nipple-areola-reconstruction
#12
Toshihiko Satake, Mayu Muto, Yu Nagashima, Shoko Haga, Yuki Homma, Reiko Nakasone, Marina Kadokura, Seiko Kou, Hiroshi Fujimoto, Jiro Maegawa
We describe a new wound management technique using a soft dressing material to stabilize the areola skin graft and protect the nipple after nipple-areola reconstruction at the final stage of breast reconstruction. We introduced a center-fenestrated multilayered hydrocellular polyurethane foam dressing material that provides adequate pressure and retains a moist environment for a smooth skin graft "take." Moreover, the reconstructed nipple can be monitored at any time through the fenestrated window for adequate blood circulation...
November 3, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29094088/factors-relating-to-late-presentation-of-patients-with-breast-cancer-in-area-2-kwazulu-natal-south-africa
#13
Sharon R Čačala, José Gilart
Purpose: Patients with breast cancer (BC) in Area 2 KwaZulu-Natal, South Africa, often present with advanced disease. We performed a review of the patients' sociodemographic characteristics and their reasons for late presentation to identify what changes could be made to improve time to presentation. Patients and Methods: Fifty women with T1, T2, T3, or T4 BC were assessed for sociodemographic data. Patients in T3 and T4 groups were asked to provide reasons for late presentation...
October 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/29093438/mapping-genomic-and-transcriptomic-alterations-spatially-in-epithelial-cells-adjacent-to-human-breast-carcinoma
#14
Moustafa Abdalla, Danh Tran-Thanh, Juan Moreno, Vladimir Iakovlev, Ranju Nair, Nisha Kanwar, Mohamed Abdalla, Jennifer P Y Lee, Jennifer Yin Yee Kwan, Thomas R Cawthorn, Keisha Warren, Nona Arneson, Dong-Yu Wang, Natalie S Fox, Bruce J Youngson, Naomi A Miller, Alexandra M Easson, David McCready, Wey L Leong, Paul C Boutros, Susan J Done
Almost all genomic studies of breast cancer have focused on well-established tumours because it is technically challenging to study the earliest mutational events occurring in human breast epithelial cells. To address this we created a unique dataset of epithelial samples ductoscopically obtained from ducts leading to breast carcinomas and matched samples from ducts on the opposite side of the nipple. Here, we demonstrate that perturbations in mRNA abundance, with increasing proximity to tumour, cannot be explained by copy number aberrations...
November 1, 2017: Nature Communications
https://www.readbyqxmd.com/read/29091591/towards-an-in-plane-methodology-to-track-breast-lesions-using-mammograms-and-patient-specific-finite-element-simulations
#15
Andrés Lapuebla-Ferri, José Cegoñino-Banzo, Antonio-José Jiménez-Mocholí, Amaya Pérez Del Palomar
In breast cancer screening or diagnosis, it is usual to combine different images in order to locate a lesion as accurately as possible. These images are generated using a single or several imaging techniques. As x-ray-based mammography is widely used, a breast lesion is located in the same plane of the image (mammogram), but tracking it across mammograms corresponding to different views is a challenging task for medical physicians. Accordingly, simulation tools and methodologies that use patient-specific numerical models can facilitate the task of fusing information from different images...
November 1, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29089810/training-oncoplastic-breast-surgeons-the-canadian-fellowship-experience
#16
J Maxwell, A Arnaout, R Hanrahan, M Brackstone
BACKGROUND: Oncoplastic breast surgery combines traditional oncologic breast conservation with plastic surgery techniques to achieve improved aesthetic and quality-of-life outcomes without sacrificing oncologic safety. Clinical uptake and training remain limited in the Canadian surgical system. In the present article, we detail the current state of oncoplastic surgery (ops) training in Canada, the United States, and worldwide, as well as the experience of a Canadian clinical fellow in ops...
October 2017: Current Oncology
https://www.readbyqxmd.com/read/29080660/indications-and-controversies-for-implant-based-breast-reconstruction-utilizing-biological-meshes
#17
REVIEW
Michael R Zenn
The advent of acellular dermal matrices (ADMs) has changed the way implant reconstruction is performed and has opened the door to muscle-sparing techniques that can be performed as an NSM (nipple-sparing mastectomy) with DTI (direct to implant) with excellent cosmesis and less patient morbidity. The article discusses differences in types of ADMs and outlines some current strategies and controversies with ADM use.
January 2018: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/29080656/patient-centered-breast-reconstruction-based-on-health-related-quality-of-life-evidence
#18
REVIEW
Jennica Platt, Toni Zhong
The article summarizes the available evidence regarding clinical decision making in breast reconstruction from the patient perspective of satisfaction and health-related quality of life. A review of generic and specific patient reported outcome measures is provided. Important components of breast reconstruction care are compared, such as timing of reconstruction, autologous and implant-based reconstruction, and the use of nipple-sparing and skin-sparing mastectomy. This evidence-based summary will be useful to guide clinicians when discussing breast reconstruction with their patients...
January 2018: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/29080650/modern-approaches-to-the-surgical-management-of-malignant-breast-disease-the-role-of-breast-conservation-complete-mastectomy-skin-and-nipple-sparing-mastectomy
#19
REVIEW
Tulin D Cil, David McCready
The armamentarium of the modern breast surgeon includes the time-tested procedures of modified radical mastectomy and lumpectomy with sentinel lymph node biopsy with postoperative radiation, but has evolved to include several options that produce excellent oncologic endpoints and improved cosmesis. These options include skin- and nipple-sparing mastectomies with immediate reconstruction as well as oncoplastic procedures that allow larger excisions and better postoperative breast shape. This article provides an overview of these modern surgical approaches for breast cancer treatment...
January 2018: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/29079443/radiofrequency-ablation-of-breast-cancer-a-retrospective-study
#20
Toshikazu Ito, Shoji Oura, Shinji Nagamine, Masato Takahashi, Naohito Yamamoto, Noboru Yamamichi, Mitsuharu Earashi, Hiroyoshi Doihara, Shigeru Imoto, Shoshu Mitsuyama, Kohei Akazawa
PURPOSE: To validate the safety and efficacy of percutaneous radiofrequency ablation (RFA) of breast carcinomas. METHODS: This retrospective study was conducted by the Breast Cancer Society for Minimally Invasive Therapy following approval from institutional review boards, and with the written informed consent of patients. A total of 386 patients with breast cancer treated with RFA at 10 institutions between July 2003 and June 2009 were identified and included in the analysis...
September 25, 2017: Clinical Breast Cancer
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