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https://www.readbyqxmd.com/read/29667019/what-is-new-in-heart-failure-management-in-2017-update-on-acc-aha-heart-failure-guidelines
#1
REVIEW
Biykem Bozkurt
PURPOSE OF REVIEW: The goal of this paper is to provide a summary of the new recommendations in the most recent 2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. The intent is to provide the background and the supporting evidence for the recommendations and to provide practical guidance for management strategies in treatment of heart failure patients...
April 17, 2018: Current Cardiology Reports
https://www.readbyqxmd.com/read/29665943/-interpretation-of-the-guidance-for-immune-thrombocytopenia-review
#2
Xiao-Yang Yang, Meng-Jie Wan, Fang-Ping Chen
Since the American Medical Association published the 2011 guidelines for immune thrombocytopenia, China has been the first to update the guidelines for immune thrombocytopenia based on evidence-based medicine. Recently, there have been many breakthroughs in clinical research published, especially the Chinese medical workers have made a prominent contribution to the treatment of the immune thrombocytopenia. However, the references of systematic drug introduction for children, adults, aged and pregnant women are still insufficient, and the first or second line treatment for some patients were ineffective...
April 2018: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/29665877/the-impact-of-2015-nhsn-catheter-associated-urinary-tract-infection-cauti-definition-change-on-central-line-associated-bloodstream-infection-clabsi-rates-and-clabsi-prevention-efforts-at-an-academic-medical-center
#3
Sonali D Advani, Rachael A Lee, Martha Long, Mariann Schmitz, Bernard C Camins
The 2015 changes in the catheter-associated urinary tract infection definition led to an increase in central line-associated bloodstream infections (CLABSIs) and catheter-related candidemia in some health systems due to the change in CLABSI attribution. However, our rates remained unchanged in 2015 and further declined in 2016 with the implementation of new vascular-access guidelines.Infect Control Hosp Epidemiol 2018;1-3.
April 18, 2018: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29665222/first-keep-it-safe-integration-of-a-complementary-medicine-service-within-a-hospital
#4
Elad Schiff, Ilana Levy, Zahi Arnon, Eran Ben-Arye, Samuel Attias
OBJECTIVES: This paper sought to explore risk/safety considerations associated with the integration of a complementary medicine (CM) service within a public academic medical centre in Israel. METHODS: We reviewed various sources pertaining to the CM service (interviews with CM staff, patients' electronic charts, service guidelines, correspondence with hospital administration) and conducted a thematic analysis to evaluate safety-related incidents during the 7 years of operation...
April 17, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29665094/newborn-screening-a-disease-changing-intervention-for-glutaric-aciduria-type-1
#5
Nikolas Boy, Katharina Mengler, Eva Thimm, Katharina A Schiergens, Thorsten Marquardt, Natalie Weinhold, Iris Marquardt, Anibh M Das, Peter Freisinger, Sarah C Grünert, Judith Vossbeck, Robert Steinfeld, Matthias R Baumgartner, Skadi Beblo, Andrea Dieckmann, Andrea Näke, Martin Lindner, Jana Heringer, Georg F Hoffmann, Chris Mühlhausen, Esther M Maier, Regina Ensenauer, Sven F Garbade, Stefan Kölker
OBJECTIVE: Untreated individuals with glutaric aciduria type 1 (GA1) commonly present with a complex, predominantly dystonic movement disorder (MD) following acute or insidious onset striatal damage. Implementation of GA1 into newborn screening (NBS) programmes has improved the short-term outcome. It remains unclear, however, whether NBS changes the long-term outcome and which variables are predictive. METHODS: This prospective, observational, multi-centre study includes 87 patients identified by NBS, four patients missed by NBS and three women with GA1 identified by positive NBS results of their unaffected children...
April 17, 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29664899/universal-versus-conditional-day-3-follow-up-for-children-with-non-severe-unclassified-fever-at-the-community-level-in-ethiopia-a-cluster-randomised-non-inferiority-trial
#6
Karin Källander, Tobias Alfvén, Tjede Funk, Ayalkibet Abebe, Abreham Hailemariam, Dawit Getachew, Max Petzold, Laura C Steinhardt, Julie R Gutman
BACKGROUND: With declining malaria prevalence and improved use of malaria diagnostic tests, an increasing proportion of children seen by community health workers (CHWs) have unclassified fever. Current community management guidelines by WHO advise that children seen with non-severe unclassified fever (on day 1) should return to CHWs on day 3 for reassessment. We compared the safety of conditional follow-up reassessment only in cases where symptoms do not resolve with universal follow-up on day 3...
April 2018: PLoS Medicine
https://www.readbyqxmd.com/read/29664697/best-practices-for-reducing-unplanned-acute-care-for-patients-with-cancer
#7
Nathan R Handley, Lynn M Schuchter, Justin E Bekelman
Variation and cost in oncology care represent a large and growing burden for the US health care system, and acute hospital care is one of the single largest drivers. Reduction of unplanned acute care is a major priority for clinical transformation in oncology; proposed changes to Medicare reimbursement for patients with cancer who suffer unplanned admissions while receiving chemotherapy heighten the need. We conducted a review of best practices to reduce unplanned acute care for patients with cancer. We searched PubMed for articles published between 2000 and 2017 and reviewed guidelines published by professional organizations...
April 17, 2018: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29664529/-clinical-guidelines-using-the-grade-system-grading-of-recommendations-assessment-development-and-evaluation
#8
Carolina Mendoza, Patricia Kraemer, Paloma Herrera, Pamela Burdiles, Dino Sepúlveda, Eliozka Núñez, Cecilia Muñoz, Ignacio Neumann
The Ministry of Health of Chile, aiming to improve the quality of clinical practice guidelines, gradually incorporated the GRADE system (Grading of Recommendations, Assessment, Development and Evaluation) to develop evidence based recommendations. This system summarizes and evaluates the certainty of the available evidence. It moves from evidence to decision in a systematic and transparent manner, based on four main dimensions: balance between benefits and harms, certainty of evidence, patient's values and preferences and use of resources...
November 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29664525/-attributes-of-recommendations-included-in-clinical-guidelines-that-influence-their-implementation-in-clinical-practice
#9
Tomás Pantoja, Dante Valles, María José Cordero
No abstract text is available yet for this article.
November 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29664358/tailored-management-of-stage-iiia-non-small-cell-lung-cancer-in-the-era-of-the-8th-edition-of-the-tnm-classification-for-lung-cancer
#10
Michael R Mueller
Stage IIIA is a very heterogeneous group encompassing locally advanced disease with T3 and T4 tumors without any nodal involvement and very small T1a primary tumors with unilateral mediastinal lymphatic disease. Tailored management defines interdisciplinary management requiring board decisions, which can sometimes be difficult particularly in stage IIIa non-small-cell lung cancer (NSCLC). Lobectomy still is standard of care even for stage I NSCLC, which increasingly is implemented using minimally invasive surgical technique...
March 2018: Future Oncology
https://www.readbyqxmd.com/read/29664328/factors-influencing-rural-end-users-acceptance-of-e-health-in-developing-countries-a-study-on-portable-health-clinic-in-bangladesh
#11
Nazmul Hossain, Fumihiko Yokota, Nazneen Sultana, Ashir Ahmed
BACKGROUND: Existing studies regarding e-health are mostly focused on information technology design and implementation, system architecture and infrastructure, and its importance in public health with ancillaries and barriers to mass adoption. However, not enough studies have been conducted to assess the end-users' reaction and acceptance behavior toward e-health, especially from the perspective of rural communities in developing countries. OBJECTIVE: The objective of this study is to explore the factors that influence rural end users' acceptance of e-health in Bangladesh...
April 17, 2018: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/29664321/eurados-work-on-internal-dosimetry
#12
B Breustedt, E Blanchardon, C-M Castellani, G Etherington, D Franck, A Giussani, W Hofmann, A-L Lebacq, W B Li, D Noßke, M A Lopez
European Radiation Dosimetry Group (EURADOS) Working Group 7 is a network on internal dosimetry that brings together researchers from more than 60 institutions in 21 countries. The work of the group is organised into task groups that focus on different aspects, such as development and implementation of biokinetic models (e.g. for diethylenetriamine penta-acetic acid decorporation therapy), individual monitoring and the dose assessment process, Monte Carlo simulations for internal dosimetry, uncertainties in internal dosimetry, and internal microdosimetry...
January 1, 2018: Annals of the ICRP
https://www.readbyqxmd.com/read/29663841/novel-heart-failure-biomarkers-why-do-we-fail-to-exploit-their-potential
#13
Arnold Piek, Weijie Du, Rudolf A de Boer, Herman H W Silljé
Plasma biomarkers are useful tools in the diagnosis and prognosis of heart failure (HF). In the last decade, numerous studies have aimed to identify novel HF biomarkers that would provide superior and/or additional diagnostic, prognostic, or stratification utility. Although numerous biomarkers have been identified, their implementation in clinical practice has so far remained largely unsuccessful. Whereas cardiac-specific biomarkers, including natriuretic peptides (ANP and BNP) and high sensitivity troponins (hsTn), are widely used in clinical practice, other biomarkers have not yet proven their utility...
April 17, 2018: Critical Reviews in Clinical Laboratory Sciences
https://www.readbyqxmd.com/read/29663318/maternal-deaths-from-hypertensive-disorders-lessons-learnt
#14
Lill T Nyfløt, Liv Ellingsen, Branka M Yli, Pål Øian, Siri Vangen
INTRODUCTION: Hypertensive disorders of pregnancy have been the most frequent cause of maternal death in Norway since 1996 and are strongly associated with substandard care. In the UK, the number of maternal deaths due to hypertensive disorders has decreased drastically due to the implementation of updated guidelines, indicating a potential for reducing the number of deaths in other countries as well. Through audits of maternal deaths, we aim to prevent future deaths from hypertensive disorders in pregnancy by identifying suboptimal factors in treatment...
April 17, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29661355/the-structure-of-medical-intensive-care-units-at-training-institutions
#15
Marc Heincelman, Ashley Duckett, Brad Keith, Andrew Schreiner, Jingwen Zhang, Edward Kilb, Benjamin Clyburn
BACKGROUND: As a result of the 2011 Accreditation Council for Graduate Medical Education (ACGME) work hour guideline implementation, the structure of intensive care unit (ICU) teams at training institutions has been affected. The impact these changes have had on the current work environment has not been well described. METHODS: The authors conducted an online survey of internal medicine program directors in 2016. The survey investigated how training institutions structure their intensive care units in reference to volume, resident housestaff and alternative coverage options, with a focus on changes made after the implementation of the 2011 ACGME duty hour restrictions...
April 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29661260/implementing-routine-blood-borne-virus-testing-for-hcv-hbv-and-hiv-at-a-london-emergency-department-uncovering-the-iceberg
#16
S Parry, N Bundle, S Ullah, G R Foster, K Ahmad, C Y W Tong, S Balasegaram, C Orkin
UK guidelines recommend routine HIV testing in high prevalence emergency departments (ED) and targeted testing for HBV and HCV. The 'Going Viral' campaign implemented opt-out blood-borne virus (BBV) testing in adults in a high prevalence ED, to assess seroprevalence, uptake, linkage to care (LTC) rates and staff time taken to achieve LTC. Diagnosis status (new/known/unknown), current engagement in care, and severity of disease was established. LTC was defined as patient informed plus ⩾1 clinic visit. A total of 6211/24 981 ED attendees were tested (uptake 25%); 257 (4...
April 17, 2018: Epidemiology and Infection
https://www.readbyqxmd.com/read/29661247/informing-implementation-of-quality-improvement-in-australian-primary-care
#17
Charlotte Hespe, Lucie Rychetnik, David Peiris, Mark Harris
BACKGROUND: Quality Improvement (QI) initiatives in primary care are effective at improving uptake of evidence based guidelines, but are difficult to implement and sustain. In Australia meso-level health organisations such as Primary health care Organisations (PHCO) offer new opportunities to implement area-wide QI programs. This study sought to identify enablers and barriers to implementation of an existing Australian QI program and to identify strategic directions that PHCOs can use in the ongoing development of QI in this environment...
April 16, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29661218/endometrial-cancer-survivors-follow-up-care-ensure-less-is-more-evaluating-patient-satisfaction-and-cost-effectiveness-of-a-reduced-follow-up-schedule-study-protocol-of-a-randomized-controlled-trial
#18
Nicole P M Ezendam, Belle H de Rooij, Roy F P M Kruitwagen, Carien L Creutzberg, Ingrid van Loon, Dorry Boll, M Caroline Vos, Lonneke V van de Poll-Franse
BACKGROUND: It has often been hypothesized that the frequency of follow-up visits for patients with early-stage endometrial cancer could be decreased. However, studies evaluating effects of a reduced follow-up schedule among this patient group are lacking. The aim of this study is to assess patient satisfaction and cost-effectiveness of a less frequent follow-up schedule compared to the schedule according to the Dutch guideline. METHODS: In this multicenter randomized controlled trial, patients diagnosed in the Netherlands with stage 1A and 1B low-risk endometrial cancer, for whom adjuvant radiotherapy is not indicated (n = 282), are randomized...
April 16, 2018: Trials
https://www.readbyqxmd.com/read/29661195/impact-of-patient-involvement-on-clinical-practice-guideline-development-a-parallel-group-study
#19
Melissa J Armstrong, C Daniel Mullins, Gary S Gronseth, Anna R Gagliardi
BACKGROUND: Patient and public involvement (PPI) is recognized as a key component of clinical practice guideline development with important implications for guideline implementability. The impact of PPI on guidelines, however, has not been rigorously assessed. Better understanding of the impact of PPI must start with guideline question formation, which drives all subsequent development steps. The aim of this study was to investigate the effect of PPI on guideline question formation and validate a conceptual model of patient and public contributions to guidelines...
April 16, 2018: Implementation Science: IS
https://www.readbyqxmd.com/read/29661022/low-rates-of-vaccination-for-herpes-zoster-in-older-people-living-with-hiv
#20
Kristine M Erlandson, Amber Streifel, Alexander Novin, Kellie Hawkins, Clayton Foster, Jacob Langness, Mary Bessesen, Julian Falutz, Abeer Moanna, David Looney, Scott Johns, Joseph Nguyen, Michael Oxman, Myron Levin
BACKGROUND: Herpes zoster (HZ) occurs at a higher age-specific rate in people living with HIV (PLWH) than in the general population. We implemented a quality improvement study to assess herpes zoster vaccine (HZV) usage among PLWH, assess HZV usage after additional reminders/prompts, and identify barriers to HZV among older PLWH. METHODS: HZV rates in PLWH were determined in six institutions with varying payment structures. For the intervention, Part 1, PLWH eligible for HZV at the University of Colorado were identified, and providers were notified of patient eligibility...
April 17, 2018: AIDS Research and Human Retroviruses
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