keyword
MENU ▼
Read by QxMD icon Read
search

Disruptive innovation

keyword
https://www.readbyqxmd.com/read/28815609/the-academic-practice-gap-strategies-for-an-enduring-problem
#1
C L Huston, B Phillips, P Jeffries, C Todero, J Rich, P Knecht, S Sommer, M P Lewis
The academic-practice gap in nursing is well documented. Academe is criticized for producing nurses insufficiently prepared to fully participate in patient care. Practice settings are criticized for having unrealistic expectations of new graduates. This article is based on a review of the literature and an exploration of contemporary practices used to bridge academic and practice partnerships. Differences in outcome expectations for new graduates between academe and practice are outlined and consequences of the gap for new graduates, patients, and employers are discussed...
August 16, 2017: Nursing Forum
https://www.readbyqxmd.com/read/28796569/cost-effectiveness-of-kinase-inhibitors-for-hematologic-malignancies-a-systematic-and-critical-review
#2
Monia Marchetti
Several genetic disruptions lead to constitutive activation of those kinases leukemic cells depend on for survival and proliferation. Kinase inhibitors (KI) are major therapeutic innovations for chronic myeloid leukemia (CML), chronic lymphoid leukemia (CLL) and myelofibrosis (MF) providing a relevant improvement of quality-adjusted survival in patients with high-risk or refractory disease. CML patients are being treated with first-generation KI imatinib since many years, achieving expected survivals longer than 10 years...
August 10, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/28795697/perovskite-based-photodetectors-materials-and-devices
#3
REVIEW
Huan Wang, Dong Ha Kim
While the field of perovskite-based optoelectronics has mostly been dominated by photovoltaics, light-emitting diodes, and transistors, semiconducting properties peculiar to perovskites make them interesting candidates for innovative and disruptive applications in light signal detection. Perovskites combine effective light absorption in the broadband range with good photo-generation yield and high charge carrier mobility, a combination that provides promising potential for exploiting sensitive and fast photodetectors that are targeted for image sensing, optical communication, environmental monitoring or chemical/biological detection...
August 10, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/28780563/implementing-a-multi-modal-support-service-model-for-the-family-caregivers-of-persons-with-age-related-macular-degeneration-a-study-protocol-for-a-randomised-controlled-trial
#4
Bamini Gopinath, Ashley Craig, Annette Kifley, Gerald Liew, Jaye Bloffwitch, Kim Van Vu, Nichole Joachim, Rob Cummins, Julie Heraghty, Timothy Broady, Alison Hayes, Paul Mitchell
INTRODUCTION: Age-related macular degeneration (AMD) is a leading cause of blindness and low vision among older adults. Previous research shows a high prevalence of distress and disruption to the lifestyle of family caregivers of persons with late AMD. This supports existing evidence that caregivers are 'hidden patients' at risk of poor health outcomes. There is ample scope for improving the support available to caregivers, and further research should be undertaken into developing services that are tailored to the requirements of family caregivers of persons with AMD...
August 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28778033/induction-of-virus-resistance-by-exogenous-application-of-double-stranded-rna
#5
REVIEW
Neena Mitter, Elizabeth A Worrall, Karl E Robinson, Zhi Ping Xu, Bernard J Carroll
Exogenous application of double-stranded RNA (dsRNA) for virus resistance in plants represents a very attractive alternative to virus resistant transgenic crops or pesticides targeting virus vectors. However, the instability of dsRNA sprayed onto plants is a major challenge as spraying naked dsRNA onto plants provides protection against homologous viruses for only 5 days. Innovative approaches, such as the use of nanoparticles as carriers of dsRNA for improved stability and sustained release, are emerging as key disruptive technologies...
August 1, 2017: Current Opinion in Virology
https://www.readbyqxmd.com/read/28777969/method-validation-and-nanoparticle-characterization-assays-for-an-innovative-amphothericin-b-formulation-to-reach-increased-stability-and-safety-in-infectious-diseases
#6
Maraine Catarina Tadini, Ana Maria de Freitas Pinheiro, Daniel Blascke Carrão, Ana Luiza Scarano Aguillera Forte, Sofia Nikolaou, Anderson R M de Oliveira, Andresa Aparecida Berretta, Franciane Marquele-Oliveira
Drug Delivery Systems (DDS) of known drugs are prominent candidates towards new and more-effective treatments of various infectious diseases as they may increase drug bioavailability, control drug delivery and target the site of action. In this sense, the encapsulation of Amphotericin B (AmB) in Nanostructured Lipid Carriers (NLCs) designed with pH-sensible phospholipids to target infectious tissues was proposed and suitable analytical methods were validated, as well as, proper nanoparticle characterization were conducted...
July 8, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28765447/what-should-oral-health-professionals-know-in-2040-executive-summary
#7
Jane A Weintraub
The "Advancing Dental Education in the 21(st) Century" project assesses current status and trends to prepare for the future. Section 3 of the project asks what knowledge and skills should dental and advanced dental education learners have to provide dental care in 2040 and how should educators be preparing them. This executive summary of five background articles in this section focuses on predoctoral education, advanced dental education, the provision of medical services within dental practice, the incorporation of oral health services into primary care and medical practice, and interprofessional education and practice...
August 2017: Journal of Dental Education
https://www.readbyqxmd.com/read/28756433/point-of-care-testing-across-rural-and-remote-emergency-departments-in-australia-staff-perceptions-of-operational-impact
#8
Maria R Dahm, Euan McCaughey, Ling Li, Johanna Westbrook, Virginia Mumford, Juliana Iles-Mann, Andrew Sargeant, Andrew Georgiou
New South Wales (NSW) Health Pathology is implementing one of the world's largest managed PoCT services across rural and remote Emergency Departments (EDs) in New South Wales, Australia to improve patient access to care. The aim of this qualitative study was to gain a context-rich understanding of the operational impact of the NSW rollout of PoCT across rural and remote ED settings as experienced by frontline clinical staff. Clinical professionals (n=14) participated in interviews and focus groups in August 2015 at four rural and remote NSW EDs...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28749952/an-innovative-way-of-thinking-nuclear-waste-management-neutron-physics-of-a-reactor-directly-operating-on-snf
#9
Bruno Merk, Dzianis Litskevich, Mark Bankhead, Richard J Taylor
A solution for the nuclear waste problem is the key challenge for an extensive use of nuclear reactors as a major carbon free, sustainable, and applied highly reliable energy source. Partitioning and Transmutation (P&T) promises a solution for improved waste management. Current strategies rely on systems designed in the 60's for the massive production of plutonium. We propose an innovative strategic development plan based on invention and innovation described with the concept of developments in s-curves identifying the current boundary conditions, and the evolvable objectives...
2017: PloS One
https://www.readbyqxmd.com/read/28747537/john-sculley-s-noble-cause-disruptive-innovation-to-transform-healthcare
#10
EDITORIAL
Govind Rao
No abstract text is available yet for this article.
July 2017: PDA Journal of Pharmaceutical Science and Technology
https://www.readbyqxmd.com/read/28741247/contaminants-of-emerging-concern-a-review-of-new-approach-in-aop-technologies
#11
REVIEW
Maryam Salimi, Ali Esrafili, Mitra Gholami, Ahmad Jonidi Jafari, Roshanak Rezaei Kalantary, Mahdi Farzadkia, Majid Kermani, Hamid Reza Sobhi
The presence of contaminants of emerging concern (CECs) such as pharmaceuticals and personal care products (PPCPs), endocrine-disrupting compounds (EDCs), flame retardants (FRs), pesticides, and artificial sweeteners (ASWs) in the aquatic environments remains a major challenge to the environment and human health. In this review, the classification and occurrence of emerging contaminants in aquatic environments were discussed in detail. It is well documented that CECs are susceptible to poor removal during the conventional wastewater treatment plants, which introduce them back to the environment ranging from nanogram per liter (e...
August 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28735772/silicon-to-syringe-cryptomarkets-and-disruptive-innovation-in-opioid-supply-chains
#12
Michael Gilbert, Nabarun Dasgupta
Cyptomarkets offer insight into the evolving interplay between online black markets and cartel-based distribution. The types and forms of heroin, fentanyl, and prescription drugs show wide diversification. In this commentary we describe changes in the conceptualizations, technologies and structures of drug supply chains in the 21st Century, with special attention to the role of cryptomarkets as tools, contexts, and drivers of innovation in public health research.
June 24, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28729843/is-a-transdisciplinary-theory-of-engagement-in-organized-settings-possible-a-concept-analysis-of-the-literature-on-employee-engagement-consumer-engagement-and-patient-engagement
#13
REVIEW
Guendalina Graffigna
Organizations are experiencing increased competition, disruptive innovation, and continuous changes in their social and economic context. Furthermore, the decrease of resources (economic and human) in such a demanding context make it imperative for organizations to find new models and strategies to make their service delivery more sustainable at the economic, environmental and psychological levels. In such a complex scenario the concept of engagement of the individuals involved in organized settings (either as service providers or as final receivers) is a promising lever for innovation...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28726632/dynamics-of-genomic-innovation-in-the-unicellular-ancestry-of-animals
#14
Xavier Grau-Bové, Guifré Torruella, Stuart Donachie, Hiroshi Suga, Guy Leonard, Thomas A Richards, Iñaki Ruiz-Trillo
Which genomic innovations underpinned the origin of multicellular animals is still an open debate. Here, we investigate this question by reconstructing the genome architecture and gene family diversity of ancestral premetazoans, aiming to date the emergence of animal-like traits. Our comparative analysis involves genomes from animals and their closest unicellular relatives (the Holozoa), including four new genomes: three Ichthyosporea and Corallochytrium limacisporum. Here we show that the earliest animals were shaped by dynamic changes in genome architecture before the emergence of multicellularity: an early burst of gene diversity in the ancestor of Holozoa, enriched in transcription factors and cell adhesion machinery, was followed by multiple and differently-timed episodes of synteny disruption, intron gain and genome expansions...
July 20, 2017: ELife
https://www.readbyqxmd.com/read/28723841/military-civilian-partnership-in-device-innovation-development-commercialization-and-application-of-resuscitative-endovascular-balloon-occlusion-of-the-aorta-reboa
#15
Todd E Rasmussen, Jonathan L Eliason
Noncompressible torso hemorrhage (NCTH) and shock is a leading cause of trauma-related mortality and evidence suggests that survival from this injury pattern has not improved in decades. As such, innovating new approaches and devices, including technologies which can be used by providers within a short of time after severe injury, is a priority for the military. Guided by wartime observations, and through partnerships with civilian academia and private investment, the military has led an effort to define resuscitative endovascular balloon occlusion of the aorta (REBOA) and assess its potential to address this problem...
July 19, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28719285/trial-of-a-novel-intervention-to-improve-multiple-food-hygiene-behaviors-in-nepal
#16
Om Prasad Gautam, Wolf-Peter Schmidt, Sandy Cairncross, Sue Cavill, Valerie Curtis
AbstractIn this study, we report on the results of a trial of an intervention to improve five food hygiene behaviors among mothers of young children in rural Nepal. This novel intervention targeted five behaviors; cleanliness of serving utensils, handwashing with soap before feeding, proper storage of cooked food, and thorough reheating and water treatment. Based on formative research and a creative process using the Behavior-Centered Design approach, an innovative intervention package was designed and delivered over a period of 3 months...
June 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28718903/affairs-of-the-heart-innovation-in-cardiovascular-research-and-development
#17
EDITORIAL
P Honig, A Terzic
Cardiovascular disease represents the single largest contributor to morbidity and mortality, yet the flow of therapeutic innovation is lagging. Globally, academia, industry, and regulatory agencies must work together to address this gap, and ensure new disruptive therapeutic modalities to address growing needs of patients and society.
August 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28708957/influenza-vaccination-in-the-elderly
#18
Jan Smetana, Roman Chlibek, Jana Shaw, Miroslav Splino, Roman Prymula
Seasonal influenza is a prevalent and serious annual illness resulting in widespread morbidity and economic disruption throughout the population; the elderly and immunocompromised are particularly vulnerable to serious sequelae and mortality. The changing demographics worldwide to an aging society have important implications for public health policy and pharmaceutical innovations. For instance, primary prevention via immunization is effective in reducing the burden of influenza illness among the elderly. However, the elderly may be insufficiently protected by vaccination due to the immunosenescence which accompanies aging...
July 14, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28699060/assessing-the-burden-of-treatment
#19
Gabriela Spencer-Bonilla, Ana R Quiñones, Victor M Montori
Current healthcare systems and guidelines are not designed to adapt to care for the large and growing number of patients with complex care needs and those with multimorbidity. Minimally disruptive medicine (MDM) is an approach to providing care for complex patients that advances patients' goals in health and life while minimizing the burden of treatment. Measures of treatment burden assess the impact of healthcare workload on patient function and well-being. At least two of these measures are now available for use with patients living with chronic conditions...
July 11, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28679874/find-your-passion-lead-with-purpose-a-health-informaticians-guide
#20
Mowafa Househ
Health Informatics is an ever evolving, changing and dynamic field that has become the disruptive innovation shaping the future of healthcare. Health informaticians face a number of challenges in the workplace such as gaining acceptance and recognition from other healthcare providers and overcoming the resistance of healthcare providers from using technology in clinical practice. Being a health informatician is not for the faint hearted, especially as resistance to the role of health informaticians continues from both healthcare providers and hospital administrators...
2017: Studies in Health Technology and Informatics
keyword
keyword
61723
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"