keyword
MENU ▼
Read by QxMD icon Read
search

Data standards

keyword
https://www.readbyqxmd.com/read/28449360/biologic-variability-of-cardiac-troponin-i-in-healthy-dogs-and-dogs-with-different-stages-of-myxomatous-mitral-valve-disease-using-standard-and-high-sensitivity-immunoassays
#1
Randolph L Winter, Ashley B Saunders, Sonya G Gordon, Matthew W Miller, Geoffrey T Fosgate, Jan S Suchodolski, Jörg M Steiner
BACKGROUND: Biologic variability (BV) is one aspect of interpreting changes in biomarker concentrations known to be clinically important in people with cardiac disease, but it has not been adequately addressed in dogs so far. OBJECTIVES: The purpose of the study was to determine BV of cardiac troponin I (cTnI) in healthy dogs and dogs with 3 stages of myxomatous mitral valve disease (MMVD). METHODS: Healthy dogs and dogs with 3 stages of MMVD were prospectively assigned to groups based on comprehensive clinical evaluation using current guidelines...
April 27, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28449307/the-efficacy-of-non-narcotic-analgesics-on-postoperative-endodontic-pain-a-systematic-review-and-meta-analysis
#2
REVIEW
Armin Shirvani, Sayna Shamszadeh, Mohammad Jafar Eghbal, Saeed Asgary
The objective of this review was to evaluate the efficacy of non-narcotic analgesics including non-steroidal anti-inflammatory drugs (NSAIDs) and/or paracetamol in the treatment of postoperative endodontic pain. Additionally, we aimed to examine the possible association of study covariates on the pain scores using meta-regression analysis. An electronic search was performed in 2016. After data extraction and quality assessment of the included studies (n=27, representing 2188 patients), meta-analysis was performed using a random-effect inverse-variance method...
April 27, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28449232/safety-pharmacokinetics-and-pharmacologic-effects-of-the-selective-androgen-receptor-modulator-gsk2881078-in-healthy-men-and-postmenopausal-women
#3
Richard V Clark, Ann C Walker, Susan Andrews, Philip Turnbull, Jeffrey A Wald, Mindy H Magee
AIM: Selective androgen receptor modulators (SARMs) induce anabolic effects on muscle without the adverse effects of androgenic steroids. In this first-in-human study, we report safety, tolerability, pharmacokinetics (PK), and pharmacodynamics of the SARM GSK2881078. METHODS: In Part A, healthy young men (n = 10) received a single dose of study drug (0 mg, 0.05 mg, 0.1 mg, 0.2 mg GSK2881078 or matching-placebo). In Part B, repeat-dose cohorts in men (n = 65) were 0...
April 27, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28449209/the-frequency-of-qtc-prolongation-among-pediatric-and-young-adult-patients-receiving-methadone-for-cancer-pain
#4
Kevin Madden, Minjeong Park, Diane Liu, Eduardo Bruera
INTRODUCTION: A prolonged corrected QT (QTc) interval in pediatric patients is defined as ≥470 msec. Methadone can cause a prolonged QTc interval that can lead to ventricular arrhythmias. The risk of methadone-induced prolongation of the QTc interval in children and young adults is unknown. The purpose of the study was to determine the frequency of QTc prolongation among pediatric and young adult patients with cancer pain on methadone treatment. METHODS: We retrospectively reviewed data for all patients on methadone during the study period...
April 27, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28449200/species-traits-as-predictors-of-range-shifts-under-contemporary-climate-change-a-review-and-meta-analysis
#5
Sarah A MacLean, Steven R Beissinger
A growing body of literature seeks to explain variation in range shifts using species' ecological and life history traits, with expectations that shifts should be greater in species with greater dispersal ability, reproductive potential, and ecological generalization. Despite strong theoretical support for species' traits as predictors of range shifts, empirical evidence from contemporary range shift studies remains limited in extent and consensus. We conducted the first comprehensive review of species' traits as predictors of range shifts, collecting results from 51 studies across multiple taxa encompassing over 11,000 species' responses for 54 assemblages of taxonomically-related species occurring together in space...
April 27, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28449115/estimation-of-state-level-prevalence-of-hepatitis-c-virus-infection-us-states-and-district-of-columbia-2010
#6
Eli S Rosenberg, Eric W Hall, Patrick S Sullivan, Travis H Sanchez, Kimberly A Workowski, John W Ward, Deborah Holtzman
Background.: Hepatitis C virus (HCV) infection is the most common chronic blood-borne infection in the United States and a leading cause of morbidity and mortality. Previous analyses of the US National Health and Nutrition Examination Survey (NHANES) indicated approximately 3.6 million noninstitutionalized persons with antibody to HCV (anti-HCV). However, state-level prevalence remains less understood and cannot be estimated reliably from NHANES alone. Methods.: We used 3 publicly available government data sources to estimate anti-HCV prevalence in each US state among noninstitutionalized persons aged ≥18 years...
April 26, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28449104/liquid-chromatographic-chemometric-techniques-for-the-simultaneous-hplc-determination-of-lansoprazole-amoxicillin-and-clarithromycin-in-commercial-preparation
#7
A Hakan Aktas, Ayse Mine Saridag
Two multivariate calibration-prediction techniques, principal component regression (PCR) and partial least-squares regression (PLSR) were applied to the chromatographic multicomponent analysis of the drug containing lansoprazole (LAN), clarithromycin (CLA) and amoxicillin (AMO). Optimum chromatographic separation of LAN, CLA and AMO with atorvastatin as the internal standard (IS) was obtained by using Xterra® RP18 column 5 μm 4.6 × 250 mm2, and 25 mM ammonium chloride buffer prepared ammonium chloride, acetonitrile and bidistilled water (45:45:10 v/v) as the mobile phase at flow rate 1...
April 26, 2017: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/28449050/cardioscape-mapping-the-cardiovascular-funding-landscape-in-europe
#8
Axel Radlach Pries, Anastasia Naoum, Helmut Habazettl, Mathias Dunkel, Robert Preissner, Caroline J Coats, Ana Tornada, Francesco Orso, Frans Van de Werf, David A Wood
Aims: The burden of cardiovascular disease is increasing worldwide, which has to be reflected by cardiovascular (CV) research in Europe. CardioScape, a FP7 funded project initiated by the European Society of Cardiology (ESC), identified where CV research is performed, how it is funded and by whom. It could be transformed into an on-line and up-to-date resource of great relevance for researchers, funding bodies and policymakers and could be a role model for mapping CV research funding in Europe and beyond...
April 25, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28448753/road-traffic-injury-in-sub-saharan-african-countries-a-systematic-review-and-summary-of-observational-studies
#9
João Ricardo N Vissoci, Daniel J Shogilev, Elizabeth Krebs, Luciano de Andrade, Igor Fiorese Vieira, Nicole Toomey, Adelia Portero Batilana, Michael Haglund, Catherine A Staton
OBJECTIVE: The aim of this study is to evaluate, through a systematic review of hospital based studies, the proportion of road traffic injuries and fatalities in SSA. METHODS: In accordance with PRISMA and MOOSE guidelines we searched the following electronic databases: PubMed, Embase, Africa-Wide Information, Global Health, and Web of Science. Articles were eligible if they measured proportion of RTIs in SSA by using hospital based studies. In addition, a reference and citation analysis was conducted as well as a data quality assessment...
April 27, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28448659/evaluation-of-ecological-momentary-assessment-for-tinnitus-severity
#10
Rachel L Goldberg, Marilyn L Piccirillo, Joyce Nicklaus, Andrew Skillington, Eric Lenze, Thomas L Rodebaugh, Dorina Kallogjeri, Jay F Piccirillo
Importance: Existing patient-reported outcome measures of tinnitus assess the severity and disability retrospectively, which may result in adequate reliability, but cannot capture the fluctuating and individualized nature of tinnitus. Experience sampling may provide an alternative. Objective: To use an ecological momentary assessment (EMA) to measure tinnitus disability and associated constructs. Design, Setting, and Participants: Forty adults with tinnitus provided self-report of their tinnitus bother using 5 questions measured by EMA, as well as standard retrospective outcome measures...
April 27, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28448542/diminished-plasma-levels-of-common-%C3%AE-chain-cytokines-in-pulmonary-tuberculosis-and-reversal-following-treatment
#11
Nathella Pavan Kumar, Vaithilingam V Banurekha, Dina Nair, Subash Babu
BACKGROUND: The immune response to tuberculosis (TB) is T cell dependent. T cells are the major facilitators of protection and effector functions with CD4+ T cells being the most important players, followed by CD8+ T cells. The common γ-chain cytokines IL-2, IL-7, IL-15, and IL-21 play a vital role in peripheral T cell growth and survival. However, the role of common γ-chain cytokines in pulmonary TB (PTB) is poorly understood. AIM AND METHODS: To examine the association of circulating common γ-chain cytokines with TB disease or infection, we examined the systemic levels of IL-2, IL-7, IL-15, and IL-21 in individuals with PTB, latent TB (LTB) or no TB infection (NTB)...
2017: PloS One
https://www.readbyqxmd.com/read/28448533/determining-the-optimal-number-and-location-of-cutoff-points-with-application-to-data-of-cervical-cancer
#12
Chung Chang, Meng-Ke Hsieh, Wen-Yi Chang, An Jen Chiang, Jiabin Chen
It is often helpful to classify biomarker values into groups of different risk levels to facilitate evaluation of a biological, physiological, or pathological state. Stratification of patients into two risk groups is commonly seen, but there is always need for more than two groups for fine assessment. So far, there are no standard methods or tools to help decide how many cutoff points are optimal. In this study, we developed a comprehensive package that included methods to determine both the optimal number and locations of cutoff points for both survival data and dichotomized outcome...
2017: PloS One
https://www.readbyqxmd.com/read/28448452/a-wireless-sensor-network-for-growth-environment-measurement-and-multi-band-optical-sensing-to-diagnose-tree-vigor
#13
Shinichi Kameoka, Shuhei Isoda, Atsushi Hashimoto, Ryoei Ito, Satoru Miyamoto, Genki Wada, Naoki Watanabe, Takashi Yamakami, Ken Suzuki, Takaharu Kameoka
We have tried to develop the guidance system for farmers to cultivate using various phenological indices. As the sensing part of this system, we deployed a new Wireless Sensor Network (WSN). This system uses the 920 MHz radio wave based on the Wireless Smart Utility Network that enables long-range wireless communication. In addition, the data acquired by the WSN were standardized for the advanced web service interoperability. By using these standardized data, we can create a web service that offers various kinds of phenological indices as secondary information to the farmers in the field...
April 27, 2017: Sensors
https://www.readbyqxmd.com/read/28448430/family-dog-assisted-adapted-physical-activity-a-case-study
#14
Amanda Tepfer, Samantha Ross, Megan MacDonald, Monique A R Udell, Craig Ruaux, Wendy Baltzer
Purpose: The aim of this case study was to examine the individual effects of an adapted physical activity, animal-assisted intervention (APA-AAI) with the family dog on motor skills, physical activity, and quality of life of a child with cerebral palsy (CP). Method: This study used an A-B-A single-subject design. The assessment phase (phase A) occurred pre- and post-intervention. This consisted of standardized assessments of motor skills, quality of life questionnaires, physical activity (measured using the GT3X+ accelerometer) and the human-animal bond...
April 27, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/28448413/the-application-of-iodine-quantitative-information-obtained-by-dual-source-dual-energy-computed-tomography-on-chemoradiotherapy-effect-monitoring-for-cervical-cancer-a-preliminary-study
#15
Changqin Jiang, Pin Yang, Junqiang Lei, Jinkui Li, Kun Yan, Feilong Li, Ruifeng Yan, Lichao Xia
OBJECTIVE: The aim of the study is to investigate the potential contribution of the iodine quantitative parameters of dual-phase dual-energy computed tomography (DECT) scanning for chemoradiotherapy (CRT) response monitoring for cervical cancer. METHODS: Patients who were pathologically certified having cervical cancer and intended for concurrent radiotherapy and chemotherapy were prospectively included in our study. Contrast-enhanced DECT scanning was performed before CRT, which was repeated after 1 month of therapy, using a dual-source CT scanner onset...
April 26, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28448399/quality-assessment-of-meta-analyses-published-in-leading-anesthesiology-journals-from-2005-to-2014
#16
Amber M Hall, Sandra Lee, David Zurakowski
Meta-analysis, when preceded by a systematic review, is considered the "gold standard" in data aggregation; however, the quality of meta-analyses is often questionable, leading to uncertainty about the accuracy of results. In this study, we evaluate the quality of meta-analyses published in 5 leading anesthesiology journals from 2005 to 2014. A total of 220 meta-analyses published in Anesthesiology, Pain, British Journal of Anaesthesia, Anaesthesia, or Anesthesia & Analgesia were identified for inclusion. The quality of each meta-analysis was determined using the Revised Assessment of Multiple Systematic Reviews (R-AMSTAR)...
April 24, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28448291/the-polypill-in-cardiovascular-prevention-evidence-limitations-and-perspective-position-paper-of-the-european-society-of-hypertension
#17
Antonio Coca, Enrico Agabiti-Rosei, Renata Cifkova, Athanasios J Manolis, Josep Redón, Giuseppe Mancia
: Antihypertensive, lipid lowering, antidiabetic and antiplatelet treatments all substantially reduce the risk of cardiovascular morbid and fatal events. In real life, however, effective implementation of these treatments is rare, and thus their contribution to cardiovascular prevention is much less than it could be, based on research data. This article reviews the pros and cons of cardiovascular prevention by the polypill approach. It is argued that the high prevalence of individuals with a multifactorial risk profile provides a strong rationale for a therapeutic strategy based on the combination in a single tablet of drugs against different risk factors...
April 26, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28448236/development-of-a-french-version-of-the-edmonton-symptom-assessment-system-revised-a-pilot-study-of-palliative-care-patients-perspectives
#18
Cheryl Nekolaichuk, Ann Huot, Valérie Gratton, Shirley H Bush, Yoko Tarumi, Sharon M Watanabe
BACKGROUND: The Edmonton Symptom Assessment System-revised (ESAS-r) is a nine-item self-report symptom intensity tool developed for palliative care patients, with the option of adding a 10th patient-specific symptom. Due to growing international uptake, the ESAS-r has been translated into different languages. There has not been agreement, however, regarding a standard process for translation into multiple languages, which also includes patients' perspectives. OBJECTIVE: The purpose of this study was to develop a French version of the ESAS-r, using a standardized translation protocol, and to obtain palliative care patients' perspectives regarding this translated tool...
April 27, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28448186/association-between-cyp3a5-genotypes-with-hypertension-in-chinese-han-population-a-case-control-study
#19
Zhanzhan Li, Peng Chen, Tao Zhou, Xiaofang Chen, Lizhang Chen
BACKGROUND: The association of CYP3A5 gene polymorphisms with hypertension in the Chinese population is unknown. We explored the association between the CYP3A5 (rs776746) gene and hypertension in the Chinese Han population. METHODS: Using a case-control design, 340 cases and 254 controls were enrolled from the Third Affiliated Hospital of South Medical University between July and December of 2015. We used a standardized questionnaire to collect data regarding age, sex, smoking, drinking, family history of hypertension, and physical exercise...
2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28448167/standardized-error-severity-score-ess-ratings-to-quantify-risk-associated-with-child-restraint-system-crs-and-booster-seat-misuse
#20
Christina M Rudin-Brown, Chelsea Kramer, Robin Langerak, Andrea Scipione, Shelley Kelsey
OBJECTIVE: Although numerous research studies have reported high levels of error and misuse of child restraint systems (CRS) and booster seats in experimental and real world scenarios, conclusions are limited because they provide little information regarding which installation issues pose the highest risk and thus should be targeted for change. Beneficial to legislating bodies and researchers alike would be a standardized, globally relevant, assessment of the potential injury risk associated with more common forms of CRS and booster seat misuse, which could be applied with observed error frequency, for example, in car seat clinics or during prototype user testing, to better identify and characterize the installation issues of greatest risk to safety...
April 27, 2017: Traffic Injury Prevention
keyword
keyword
61720
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"