keyword
https://read.qxmd.com/read/38418600/low-migratory-connectivity-and-similar-migratory-strategies-in-a-shorebird-with-contrasting-wintering-population-trends-in-europe-and-west-africa
#21
JOURNAL ARTICLE
Teresa Catry, Edna Correia, Jorge S Gutiérrez, Pierrick Bocher, Frédéric Robin, Pierre Rousseau, José P Granadeiro
Migratory shorebird populations are declining worldwide, showing an apparent inability to respond to the interplaying challenges emerging along their flyways. Within the East Atlantic Flyway, non-breeding populations show moderate to strong declines in Sub-Saharan Africa, contrasting with stable or increasing trends in Europe. Local factors are insufficient to explain the opposite tendencies and, therefore, investigating migratory strategies and connectivity of these populations may help identifying the drivers of their demography...
February 28, 2024: Scientific Reports
https://read.qxmd.com/read/38407824/renal-replacement-therapy-initiation-strategies-in-comatose-patients-with-severe-acute-kidney-injury-a-secondary-analysis-of-a-multicenter-randomized-controlled-trial
#22
JOURNAL ARTICLE
Thomas Rambaud, David Hajage, Didier Dreyfuss, Saïd Lebbah, Laurent Martin-Lefevre, Guillaume Louis, Sébastien Moschietto, Dimitri Titeca-Beauport, Béatrice La Combe, Bertrand Pons, Nicolas De Prost, Sébastien Besset, Alain Combes, Adrien Robine, Marion Beuzelin, Julio Badie, Guillaume Chevrel, Julien Bohe, Elisabeth Coupez, Nicolas Chudeau, Saber Barbar, Christophe Vinsonneau, Jean-Marie Forel, Didier Thevenin, Eric Boulet, Karim Lakhal, Nadia Aissaoui, Steven Grange, Marc Leone, Guillaume Lacave, Saad Nseir, Florent Poirson, Julien Mayaux, Karim Ashenoune, Guillaume Geri, Kada Klouche, Guillaume Thiery, Laurent Argaud, Bertrand Rozec, Cyril Cadoz, Pascal Andreu, Jean Reignier, Jean-Damien Ricard, Jean-Pierre Quenot, Romain Sonneville, Stéphane Gaudry
PURPOSE: The effect of renal replacement therapy (RRT) in comatose patients with acute kidney injury (AKI) remains unclear. We compared two RRT initiation strategies on the probability of awakening in comatose patients with severe AKI. METHODS: We conducted a post hoc analysis of a trial comparing two delayed RRT initiation strategies in patients with severe AKI. Patients were monitored until they had oliguria for more than 72 h and/or blood urea nitrogen higher than 112 mg/dL and then randomized to a delayed strategy (RRT initiated after randomization) or a more-delayed one (RRT initiated if complication occurred or when blood urea nitrogen exceeded 140 mg/dL)...
February 26, 2024: Intensive Care Medicine
https://read.qxmd.com/read/38389267/occlusal-outcomes-in-non-robin-sequence-patients-with-isolated-cleft-palate
#23
JOURNAL ARTICLE
Catherine Beaumont, Audrey Bellerive, Anne-Sophie Julien, Jacques E Leclerc
OBJECTIVES: 1. To assess the skeletal class occlusion and lateral cephalometry in children with isolated cleft palates (non-Robin sequence) and 2. to identify associations between these findings and pre-palatoplasty cleft palate measurements. STUDY DESIGN: Retrospective cohort study. SETTING: North American Institutional Tertiary Paediatric Center. PATIENTS: Our cleft database was reviewed, and patients were included if they had an isolated cleft palate without a Robin Sequence diagnosis, had a Furlow palatoplasty and had available per operative cleft palate measurements and available lateral cephalogram between 6 and 8 years old...
February 22, 2024: Cleft Palate-craniofacial Journal
https://read.qxmd.com/read/38387381/bias-reduction-using-combined-stain-normalization-and-augmentation-for-ai-based-classification-of-histological-images
#24
JOURNAL ARTICLE
Camille Franchet, Robin Schwob, Guillaume Bataillon, Charlotte Syrykh, Sarah Péricart, François-Xavier Frenois, Frédérique Penault-Llorca, Magali Lacroix-Triki, Laurent Arnould, Jérôme Lemonnier, Jean-Marc Alliot, Thomas Filleron, Pierre Brousset
Artificial intelligence (AI)-assisted diagnosis is an ongoing revolution in pathology. However, a frequent drawback of AI models is their propension to make decisions based rather on bias in training dataset than on concrete biological features, thus weakening pathologists' trust in these tools. Technically, it is well known that microscopic images are altered by tissue processing and staining procedures, being one of the main sources of bias in machine learning for digital pathology. So as to deal with it, many teams have written about color normalization and augmentation methods...
February 8, 2024: Computers in Biology and Medicine
https://read.qxmd.com/read/38380940/regional-practice-variation-and-outcomes-in-the-standard-versus-accelerated-initiation-of-renal-replacement-therapy-in-acute-kidney-injury-starrt-aki-trial-a-post-hoc-secondary-analysis
#25
JOURNAL ARTICLE
Suvi T Vaara, Ary Serpa Neto, Rinaldo Bellomo, Neill K J Adhikari, Didier Dreyfuss, Martin Gallagher, Stephane Gaudry, Eric Hoste, Michael Joannidis, Ville Pettilä, Amanda Y Wang, Kianoush Kashani, Ron Wald, Sean M Bagshaw, Marlies Ostermann
OBJECTIVES: Among patients with severe acute kidney injury (AKI) admitted to the ICU in high-income countries, regional practice variations for fluid balance (FB) management, timing, and choice of renal replacement therapy (RRT) modality may be significant. DESIGN: Secondary post hoc analysis of the STandard vs. Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial (ClinicalTrials.gov number NCT02568722). SETTING: One hundred-fifty-three ICUs in 13 countries...
February 2024: Critical care explorations
https://read.qxmd.com/read/38377616/use-of-at-breast-supplementers-to-facilitate-feeding-solely-at-the-breast-for-infants-with-retrognathia-two-case-studies
#26
JOURNAL ARTICLE
Moira Haggarty Edwards, Daphne Doble, Laura Ball, M Elise Graham
Objective: Infants with significant retrognathia often have difficulty forming a latch adequate to establish exclusive breastfeeding. This article describes the use of at-breast supplementers (ABSs) to facilitate extended breastfeeding relationships, even when supplementation is necessary for growth. Methods: Two cases are described where infants with severe retrognathia initially struggled with weight gain necessitating supplementation but were able to ultimately exclusively feed at-breast with the use of ABSs...
February 20, 2024: Breastfeeding Medicine
https://read.qxmd.com/read/38373851/long-term-cardiovascular-risks-and-the-impact-of-statin-treatment-on-socioeconomic-inequalities-a-microsimulation-model
#27
JOURNAL ARTICLE
Runguo Wu, Claire Williams, Junwen Zhou, Iryna Schlackow, Jonathan Emberson, Christina Reith, Anthony Keech, John Robson, Jane Armitage, Alastair Gray, John Simes, Colin Baigent, Borislava Mihaylova, Jane Armitage, Colin Baigent, Elizabeth Barnes, Lisa Blackwell, Rory Collins, Kelly Davies, Jonathan Emberson, Jordan Fulcher, Heather Halls, William G Herrington, Lisa Holland, Anthony Keech, Adrienne Kirby, Borislava Mihaylova, Rachel O'Connell, David Preiss, Christina Reith, John Simes, Kate Wilson, Michael Blazing, Eugene Braunwald, James de Lemos, Sabina Murphy, Terje R Pedersen, Marc Pfeffer, Harvey White, Stephen Wiviott, Michael Clearfield, John R Downs, Antonio Gotto, Stephen Weis, Bengt Fellström, Hallvard Holdaas, Alan Jardine, Terje R Pedersen, David Gordon, Barry Davis, Curt Furberg, Richard Grimm, Sara Pressel, Jeffrey L Probstfield, Mahboob Rahman, Lara Simpson, Michael Koren, Björn Dahlöf, Ajay Gupta, Neil Poulter, Peter Sever, Hans Wedel, Robert H Knopp, Stuart Cobbe, Bengt Fellström, Hallvard Holdaas, Alan Jardine, Roland Schmieder, Faiez Zannad, D John Betteridge, Helen M Colhoun, Paul N Durrington, John Fuller, Graham A Hitman, Andrew Neil, Eugene Braunwald, Barry Davis, C Morton Hawkins, Lemuel Moyé, Marc Pfeffer, Frank Sacks, John Kjekshus, Hans Wedel, John Wikstrand, Christoph Wanner, Vera Krane, Maria Grazia Franzosi, Roberto Latini, Donata Lucci, Aldo Maggioni, Roberto Marchioli, Enrico B Nicolis, Luigi Tavazzi, Gianni Tognoni, Jackie Bosch, Eva Lonn, Salim Yusuf, Jane Armitage, Louise Bowman, Rory Collins, Anthony Keech, Martin Landray, Sarah Parish, Richard Peto, Peter Sleight, John Jp Kastelein, Terje R Pedersen, Robert Glynn, Antonio Gotto, John Jp Kastelein, Wolfgang Koenig, Jean MacFadyen, Paul M Ridker, Anthony Keech, Stephen MacMahon, Ian Marschner, Andrew Tonkin, John Shaw, John Simes, Harvey White, Patrick W Serruys, Genell Knatterud, Gerard J Blauw, Stuart Cobbe, Ian Ford, Peter Macfarlane, Chris Packard, Naveed Sattar, James Shepherd, Stella Trompet, Eugene Braunwald, Christopher P Cannon, Sabina Murphy, Rory Collins, Jane Armitage, Louise Bowman, Richard Bulbulia, Richard Haynes, Sarah Parish, Richard Peto, Peter Sleight, Pierre Amarenco, K Michael Welch, John Kjekshus, Terje R Pedersen, Lars Wilhelmsen, Philip Barter, Antonio Gotto, John LaRosa, John Jp Kastelein, James Shepherd, Stuart Cobbe, Ian Ford, Sharon Kean, Peter Macfarlane, Chris Packard, Michele Roberston, Naveed Sattar, James Shepherd, Robin Young, Hiroyuki Arashi, Robert Clarke, Marcus Flather, Shinya Goto, Uri Goldbourt, Jemma Hopewell, G Kees Hovingh, George Kitas, Connie Newman, Marc S Sabatine, Gregory G Schwartz, Liam Smeeth, Jonathan Tobert, John Varigos, Junichi Yamamguchi
BACKGROUND: UK cardiovascular disease (CVD) incidence and mortality have declined in recent decades but socioeconomic inequalities persist. AIM: To present a new CVD model, and project health outcomes and the impact of guideline-recommended statin treatment across quintiles of socioeconomic deprivation in the UK. DESIGN AND SETTING: A lifetime microsimulation model was developed using 117 896 participants in 16 statin trials, 501 854 UK Biobank (UKB) participants, and quality-of-life data from national health surveys...
February 19, 2024: British Journal of General Practice
https://read.qxmd.com/read/38373442/online-resources-for-robin-sequence-an-analysis-of-readability
#28
JOURNAL ARTICLE
R Browne, C M Hurley, S Carr, C de Blacam
The objective was to evaluate the readability of easily accessible parent-directed information concerning Robin Sequence (RS) online, compared to the American Medical Association (AMA)-recommended sixth grade (age 11-12) readability level. A Google search of the term "Pierre Robin Sequence information" was performed. The first ten websites were evaluated using six commonly used readability formulas. Sample texts from three websites were 'translated' by the authors, with the aim of achieving a sixth grade readability level...
February 19, 2024: Cleft Palate-craniofacial Journal
https://read.qxmd.com/read/38373407/weight-gain-of-infants-with-robin-sequence-treated-nonsurgically-using-the-stanford-orthodontic-airway-plate-soap-1-year-follow-up
#29
JOURNAL ARTICLE
HyeRan Choo, Alexis S Davis, Lisa C Bain, HyoWon Ahn
OBJECTIVE: To identify weight gain trends of infants with Robin sequence (RS) treated by the Stanford Orthodontic Airway Plate treatment (SOAP). DESIGN: Retrospective longitudinal cohort study. SETTING: Single tertiary referral hospital. PATIENTS: Eleven infants with RS treated with SOAP. INTERVENTIONS: Nonsurgical SOAP. MAIN OUTCOME MEASURES: Body weight, Weight-for-age (WFA) Z-scores, and WFA percentiles at birth (T0), SOAP delivery (T1), SOAP graduation (T2), and 12-months old (T3)...
February 19, 2024: Cleft Palate-craniofacial Journal
https://read.qxmd.com/read/38372169/gas-exchange-parameters-for-the-prediction-of-obstructive-sleep-apnea-in-infants
#30
JOURNAL ARTICLE
Romane Gyapay, Iulia Ioan, Marine Thieux, Aurore Guyon, Sonia Ayari, Eglantine Hullo, Patricia Franco, Laurianne Coutier
STUDY OBJECTIVES: Sleep laboratory polysomnography (PSG) is the gold standard for obstructive sleep apnea (OSA) diagnosis in infants, but its access remains limited. Oximetry-capnography is another simple and widely used tool that can provide information on the presence of desaturations and alveolar hypoventilation. However, its reliability is debated. This study aimed at examining its use in determining OSA severity in infants. METHODS: This retrospective study was conducted in a sleep unit in a tertiary hospital, in infants < 4 months old with clinical signs of OSA or Pierre Robin Sequence (PRS) who underwent a one-night PSG coupled with oximetry-capnography...
February 19, 2024: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://read.qxmd.com/read/38359806/persistent-covid-19-a-case-report-of-an-immunocompromised-patient-and-a-literature-review
#31
Sirine Bekkaoui, Geoffroy Venton, Fannie Bretelle, Victoria Garrido, Victor Chabbert, Stéphane Gayet, Paul Dalmas, Antoine Tichadou, Pierre-André Jarrot, Patrick Villani, Aurélie Daumas, Robin Arcani
Introduction Immunocompromised patients can show prolonged shedding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and persistent symptoms, which is called persistent COVID-19. Case presentation We report a case of an immunocompromised patient who was treated for mantle cell lymphoma and was suffering from B-cell depletion. The patient developed persistent COVID-19, which was confirmed by real-time polymerase chain reaction (RT-PCR) tests in only sputum and bronchoalveolar fluid which remained positive for at least 112 days...
February 15, 2024: Acta Haematologica
https://read.qxmd.com/read/38338665/dysfunctional-postnatal-mitochondrial-energy-metabolism-in-a-patient-with-neurodevelopmental-defects-caused-by-intrauterine-growth-restriction-due-to-idiopathic-placental-insufficiency
#32
JOURNAL ARTICLE
Martine Uittenbogaard, Andrea L Gropman, Matthew T Whitehead, Christine A Brantner, Eliana Gropman, Anne Chiaramello
We report the case of a four-year-old male patient with a complex medical history born prematurely as the result of intrauterine growth restriction due to placental insufficiency. His clinical manifestations included severe neurodevelopmental deficits, global developmental delay, Pierre-Robin sequence, and intractable epilepsy with both generalized and focal features. The proband's low levels of citrulline and lactic acidosis provoked by administration of Depakoke were evocative of a mitochondrial etiology...
January 23, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38323076/pierre-robin-sequence-coexisting-with-ectopic-kidney-bilateral-developmental-hip-dysplasia-in-a-child-a-rare-case-report
#33
Eshaan Mishra, Rajesh Rana, Sarthak Sahoo
Pierre Robin sequence is a rare congenital disorder with variable associations. A two-year-old female child was brought in with complaints of an abnormal gait and right lower limb shortening. A comprehensive clinical evaluation unveiled facial characteristics resembling those of Pierre Robin Sequence, including micrognathia, a cleft palate, and glossoptosis. The child also exhibited retrognathia, a low posterior hairline, bilateral developmental dysplasia of the hips, right foot syndactyly, and a left ectopic kidney as confirmed by ultrasonography...
February 2024: Journal of Clinical Orthopaedics and Trauma
https://read.qxmd.com/read/38316926/microbemasst-a-taxonomically-informed-mass-spectrometry-search-tool-for-microbial-metabolomics-data
#34
JOURNAL ARTICLE
Simone Zuffa, Robin Schmid, Anelize Bauermeister, Paulo Wender P Gomes, Andres M Caraballo-Rodriguez, Yasin El Abiead, Allegra T Aron, Emily C Gentry, Jasmine Zemlin, Michael J Meehan, Nicole E Avalon, Robert H Cichewicz, Ekaterina Buzun, Marvic Carrillo Terrazas, Chia-Yun Hsu, Renee Oles, Adriana Vasquez Ayala, Jiaqi Zhao, Hiutung Chu, Mirte C M Kuijpers, Sara L Jackrel, Fidele Tugizimana, Lerato Pertunia Nephali, Ian A Dubery, Ntakadzeni Edwin Madala, Eduarda Antunes Moreira, Leticia Veras Costa-Lotufo, Norberto Peporine Lopes, Paula Rezende-Teixeira, Paula C Jimenez, Bipin Rimal, Andrew D Patterson, Matthew F Traxler, Rita de Cassia Pessotti, Daniel Alvarado-Villalobos, Giselle Tamayo-Castillo, Priscila Chaverri, Efrain Escudero-Leyva, Luis-Manuel Quiros-Guerrero, Alexandre Jean Bory, Juliette Joubert, Adriano Rutz, Jean-Luc Wolfender, Pierre-Marie Allard, Andreas Sichert, Sammy Pontrelli, Benjamin S Pullman, Nuno Bandeira, William H Gerwick, Katia Gindro, Josep Massana-Codina, Berenike C Wagner, Karl Forchhammer, Daniel Petras, Nicole Aiosa, Neha Garg, Manuel Liebeke, Patric Bourceau, Kyo Bin Kang, Henna Gadhavi, Luiz Pedro Sorio de Carvalho, Mariana Silva Dos Santos, Alicia Isabel Pérez-Lorente, Carlos Molina-Santiago, Diego Romero, Raimo Franke, Mark Brönstrup, Arturo Vera Ponce de León, Phillip Byron Pope, Sabina Leanti La Rosa, Giorgia La Barbera, Henrik M Roager, Martin Frederik Laursen, Fabian Hammerle, Bianka Siewert, Ursula Peintner, Cuauhtemoc Licona-Cassani, Lorena Rodriguez-Orduña, Evelyn Rampler, Felina Hildebrand, Gunda Koellensperger, Harald Schoeny, Katharina Hohenwallner, Lisa Panzenboeck, Rachel Gregor, Ellis Charles O'Neill, Eve Tallulah Roxborough, Jane Odoi, Nicole J Bale, Su Ding, Jaap S Sinninghe Damsté, Xue Li Guan, Jerry J Cui, Kou-San Ju, Denise Brentan Silva, Fernanda Motta Ribeiro Silva, Gilvan Ferreira da Silva, Hector H F Koolen, Carlismari Grundmann, Jason A Clement, Hosein Mohimani, Kirk Broders, Kerry L McPhail, Sidnee E Ober-Singleton, Christopher M Rath, Daniel McDonald, Rob Knight, Mingxun Wang, Pieter C Dorrestein
microbeMASST, a taxonomically informed mass spectrometry (MS) search tool, tackles limited microbial metabolite annotation in untargeted metabolomics experiments. Leveraging a curated database of >60,000 microbial monocultures, users can search known and unknown MS/MS spectra and link them to their respective microbial producers via MS/MS fragmentation patterns. Identification of microbe-derived metabolites and relative producers without a priori knowledge will vastly enhance the understanding of microorganisms' role in ecology and human health...
February 2024: Nature Microbiology
https://read.qxmd.com/read/38311310/-first-line-management-of-infertile-couple-guidelines-for-clinical-practice-of-the-french-college-of-obstetricians-and-gynecologists-2022
#35
Charlotte Sonigo, Geoffroy Robin, Florence Boitrelle, Eloïse Fraison, Nathalie Sermondade, Emmanuelle Mathieu d' Argent, Pierre-Emmanuel Bouet, Charlotte Dupont, Hélène Creux, Maeliss Peigné, Olivier Pirrello, Sabine Trombert, Emmanuel Lecorche, Ludivine Dion, Laurence Rocher, Emmanuel Arama, Valérie Bernard, Margaux Monnet, Laura Miquel, Eva Birsal, Stéphanie Haïm Boukobza, Ingrid Plotton, Célia Ravel, Véronika Grzegorczyk Martin, Eric Huyghe, Hugo G A Dupuis, Tiphaine Lefevre, Florence Leperlier, Léna Bardet, Imane Lalami, Camille Robin, Virginie Simon, Laura Dijols, Justine Riss, Antoine Koch, Clément Bailly, Constance Rio, Marine Lebret, Margaux Jegaden, Hervé Fernandez, Jean-Luc Pouly, Antoine Torre, Jean-Marie Antoine, Blandine Courbiere
OBJECTIVE: To update the 2010 CNGOF clinical practice guidelines for the first-line management of infertile couples. MATERIALS AND METHODS: Five major themes (first-line assessment of the infertile woman, first-line assessment of the infertile man, prevention of exposure to environmental factors, initial management using ovulation induction regimens, first-line reproductive surgery) were identified, enabling 28 questions to be formulated using the PICO (Patients, Intervention, Comparison, Outcome) format...
February 2, 2024: Gynecologie, Obstetrique, Fertilite & Senologie
https://read.qxmd.com/read/38305773/managing-non-24-hour-sleep-wake-disorder-with-ramelteon-in-a-12-year-old-girl-with-pierre-robin-sequence-and-developmental-delay-a-case-report
#36
Cheng-Hsien Huang
We recently observed a case involving a 12-year-old sighted girl who exhibited symptoms typical of non-24-hour sleep-wake disorder (N24SWD). This disorder, more commonly found in blind individuals, presents a unique challenge when diagnosed in those with vision. Several interventions can be attempted, ranging from behavioral adjustments to light therapy. Although melatonin has been noted for its effectiveness in realigning the patient's sleep-wake cycle, the use of ramelteon, a melatonin receptor agonist, has seldom been reported in managing N24SWD...
February 2, 2024: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://read.qxmd.com/read/38303142/application-of-the-micronaps-classification-for-robin-sequence
#37
JOURNAL ARTICLE
Cory M Resnick, Eliot Katz, Alistair Varidel
OBJECTIVE: The only findings consistent among infants with Robin sequence (RS) are the presence of micrognathia, glossoptosis, and upper airway obstruction (UAO). Feeding and growth dysfunction are typical. The etiopathogenesis of these findings, however, is highly variable, ranging from sporadic to syndromic causes, with widely disparate levels of severity. This heterogeneity has created inconsistency within RS literature and debate about appropriate workup and treatment. Despite several attempts at stratification, no system has been broadly adopted...
February 1, 2024: Cleft Palate-craniofacial Journal
https://read.qxmd.com/read/38291222/the-index-of-intrusion-control-iic-capturing-individual-variability-in-intentional-intrusion-control-in-the-laboratory
#38
JOURNAL ARTICLE
Stephanie M Ashton, Pierre Gagnepain, Per Davidson, Robin Hellerstedt, Akul Satish, Tom Smeets, Conny W E M Quaedflieg
Intrusive memories can be downregulated using intentional memory control, as measured via the Think/No-Think paradigm. In this task, participants retrieve or suppress memories in response to an associated reminder cue. After each suppression trial, participants rate whether the association intruded into awareness. Previous research has found that repeatedly exerting intentional control over memory intrusions reduces their frequency. This decrease is often summarised with a linear index, which may miss more complex patterns characterising the temporal dynamics of intrusion control...
January 30, 2024: Behavior Research Methods
https://read.qxmd.com/read/38288603/variation-of-subclinical-psychosis-across-16-sites-in-europe-and-brazil-findings-from-the-multi-national-eu-gei-study
#39
JOURNAL ARTICLE
Giuseppe D'Andrea, Diego Quattrone, Kathryn Malone, Giada Tripoli, Giulia Trotta, Edoardo Spinazzola, Charlotte Gayer-Anderson, Hannah E Jongsma, Lucia Sideli, Simona A Stilo, Caterina La Cascia, Laura Ferraro, Antonio Lasalvia, Sarah Tosato, Andrea Tortelli, Eva Velthorst, Lieuwe de Haan, Pierre-Michel Llorca, Paulo Rossi Menezes, Jose Luis Santos, Manuel Arrojo, Julio Bobes, Julio Sanjuán, Miguel Bernardo, Celso Arango, James B Kirkbride, Peter B Jones, Bart P Rutten, Jim Van Os, Jean-Paul Selten, Evangelos Vassos, Franck Schürhoff, Andrei Szöke, Baptiste Pignon, Michael O'Donovan, Alexander Richards, Craig Morgan, Marta Di Forti, Ilaria Tarricone, Robin M Murray
BACKGROUND: Incidence of first-episode psychosis (FEP) varies substantially across geographic regions. Phenotypes of subclinical psychosis (SP), such as psychotic-like experiences (PLEs) and schizotypy, present several similarities with psychosis. We aimed to examine whether SP measures varied across different sites and whether this variation was comparable with FEP incidence within the same areas. We further examined contribution of environmental and genetic factors to SP. METHODS: We used data from 1497 controls recruited in 16 different sites across 6 countries...
January 30, 2024: Psychological Medicine
https://read.qxmd.com/read/38283465/anesthetic-management-of-a-cesarean-section-for-preeclampsia-in-a-parturient-with-stickler-syndrome-a-case-report
#40
Kenichi Takechi, Mayuko Fujimoto, Ichiro Shimizu
Stickler syndrome is a connective tissue disease with the pathogenic involvement of procollagen genes. It is characterized by ocular and joint abnormalities, hearing loss, and midfacial hypoplasia. In Stickler syndrome, the Pierre Robin sequence is a possible complication. A 30-year-old female was admitted at 33 weeks of gestation. She had a genetic diagnosis of Stickler syndrome type 1. The parturient was diagnosed with preeclampsia, and a decision was made to terminate the pregnancy via cesarean section. Combined spinal epidural anesthesia was planned...
December 2023: Curēus
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