keyword
MENU ▼
Read by QxMD icon Read
search

Evidence standards

keyword
https://www.readbyqxmd.com/read/29227955/developing-and-validating-a-perinatal-depression-screening-tool-in-kenya-blending-western-criteria-with-local-idioms-a-mixed-methods-study
#1
Eric P Green, Hawa Tuli, Edith Kwobah, D Menya, Irene Chesire, Christina Schmidt
BACKGROUND: Routine screening for perinatal depression is not common in most primary health care settings. The U.S. Preventive Services Task Force only recently updated their recommendation on depression screening to specifically recommend screening during the pre- and postpartum periods. While practitioners in high-income countries can respond to this new recommendation by implementing one of several existing depression screening tools developed in Western contexts, such as the Edinburgh Postnatal Depression Scale (EPDS) or the Patient Health Questionnaire-9 (PHQ-9), these tools lack strong evidence of cross-cultural equivalence, validity for case finding, and precision in measuring response to treatment in developing countries...
December 2, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29227445/mobile-hearing-testing-applications-and-the-diagnosis-of-sudden-sensorineural-hearing-loss-a-cautionary-tale
#2
Rosh K V Sethi, Iman Ghanad, Vivek Kanumuri, Barbara Herrmann, Elliott D Kozin, Aaron K Remenschneider
OBJECTIVE: Mobile hearing applications (apps) are available for hearing testing, personal sound amplification, as well as hearing aid modulation. Hearing testing apps are gaining popularity, especially in resource-limited settings. The reliability of mobile hearing testing apps, however, is not well characterized. PATIENTS/INTERVENTIONS: A case study of a single patient with a complaint of sudden hearing loss presenting to a tertiary-care hospital. MAIN OUTCOME MEASURE: Comparison of a mobile hearing testing app results with standard audiogram...
January 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29227322/no-clear-benefit-of-chlorhexidine-use-at-home-before-surgical-preparation
#3
Melvin Chugh Makhni, Kolawole Jegede, Joseph Lombardi, Susan Whittier, Prakash Gorroochurn, Ronald A Lehman, K Daniel Riew
INTRODUCTION: Several studies have evaluated the efficacy of home use of chlorhexidine before surgery to reduce bacterial colonization. However, these studies have provided conflicting evidence about the potential efficacy of this strategy in decreasing bacterial loads and infection rates across surgical populations, and no prior study has analyzed the benefit of this intervention before spine surgery. We prospectively analyzed the effectiveness of chlorhexidine gluconate wipes for decreasing bacterial counts on the posterior neck...
December 11, 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/29227277/use-of-complementary-and-alternative-medicine-in-georgia
#4
I Nadareishvili, K Lunze, N Tabagari, A Beraia, G Pkhakadze
In Georgia, like in most countries globally, people commonly resort to complementary and alternative medicine (CAM). However, not much is known about CAM practices there. The aim of the study was to document common practices of CAM in Georgia and related patient attitudes. We collected data from peoples who commonly use CAM at 20 service provision centers in Georgia using cluster sampling from 300 patients. We admininstered a cross-sectional survey and conducted descriptive statistical analyses. People in Georgia use CAM either for prevention to improve general health (33%) or to treat chronic conditions (36%), spending about 25 Euros per month out of pocket...
November 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29227199/two-step-irradiance-treatment-can-achieve-excellent-pain-control-during-red-light-5-aminolevulinic-acid-photodynamic-therapy-for-actinic-keratoses
#5
Gyorgy Paragh, Nathalie C Zeitouni
OBJECTIVE: To evaluate the ability of two-step irradiance to maintain pain control during red light 5-aminolevulinic acid (ALA) photodynamic therapy (PDT) for actinic keratoses (AK) and assess factors influencing pain. BACKGROUND: PDT provides excellent clinical and cosmetic results in the treatment AK and early basal cell carcinomas (BCC). Widespread use of PDT is limited, in part, by pain. A two-step irradiance method for PDT has previously been shown to significantly reduce PDT-associated pain during the treatment of BCC, but the ability of this method to limit pain during the treatment of AKs has not been reported...
December 11, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29227157/systematic-review-of-the-diagnostic-accuracy-of-the-non-english-versions-of-addenbrooke-s-cognitive-examination%C3%A2-%C3%A2-revised-and-iii
#6
Noor Habib, Joshua Stott
OBJECTIVE: This systematic review aims to review the evidence for the diagnostic accuracy of the non-English updated versions of Addenbrooke's Cognitive Examination (ACE) - the ACE-Revised (ACE-R) and the ACE-III - in the diagnosis of dementia. METHODS: A systematic search resulted in 16 eligible studies evaluating the diagnostic accuracy of ACE-R and ACE-III in ten different languages. Most studies were assessed as of medium to low quality using Standards for Reporting of Diagnostic Accuracy (STARD) guidance...
December 11, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/29226949/thrombolysis-for-acute-upper-extremity-deep-vein-thrombosis
#7
REVIEW
Joshua Feinberg, Emil Eik Nielsen, Janus C Jakobsen
BACKGROUND: About 5% to 10% of all deep vein thromboses occur in the upper extremities. Serious complications of upper extremity deep vein thrombosis, such as post-thrombotic syndrome and pulmonary embolism, may in theory be avoided using thrombolysis. No systematic review has assessed the effects of thrombolysis for the treatment of individuals with acute upper extremity deep vein thrombosis. OBJECTIVES: To assess the beneficial and harmful effects of thrombolysis for the treatment of individuals with acute upper extremity deep vein thrombosis...
December 11, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29226657/short-centrifugation-to-ameliorate-turn-around-time-in-routine-coagulation-testing
#8
Albrecht Pfaefflin, Karen Schuster, Ruediger Braun
BACKGROUND: Fast and timely analysis of coagulation parameters is mandatory in hospital laboratories as the results are decisive for diagnosis and treatment in emergency patients. An important factor in TAT (turn-around time) prolongation is centrifugation of all samples prior to analysis. According to literature and most current SOPs (standard operation protocols) centrifugation time is given with 10 minutes at approximately 2,000 g and cannot be reduced without infringement of standards...
November 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/29226377/two-and-three-dimensional-transthoracic-echocardiographic-assessment-of-superior-vena-cava-crista-terminalis-and-right-atrial-appendage-using-the-right-parasternal-approach
#9
Mohammed J Arisha, Ming C Hsiung, Navin C Nanda, Ankur Gupta, David C George, Ahmed Elkaryoni, Kirolos Barssoum, Ahmed H Mohamed, Swetha Srialluri
BACKGROUND: The noninvasive assessment of superior vena cava (SVC), crista terminalis (CT), and the right atrial appendage (RAA) has clinical implications in determining the right atrium (RA) pressure in adult patients in whom the inferior vena cava cannot be imaged, in planning electrophysiological procedures and for evaluation of thrombi in RA/RAA. It is difficult to image these structures using standard two-dimensional transthoracic echocardiography (2DTTE), but the right parasternal approach has shown promise in the very few studies published so far...
December 11, 2017: Echocardiography
https://www.readbyqxmd.com/read/29226368/applicability-of-the-fish-embryo-acute-toxicity-fet-test-oecd-236-in-the-regulatory-context-of-reach
#10
REVIEW
Marta Sobanska, Stefan Scholz, Anna-Maija Nyman, Romanas Cesnaitis, Simon Gutierrez Alonso, Nils KlüVer, Ralph KüHne, Henrik Tyle, Joop De Knecht, Zhichao Dang, Ivar Lundbergh, Claudio Carlon, Wim De Coen
In 2013 the OECD Test Guideline (TG 236) for Fish Embryo Acute Toxicity (FET) was adopted. It determines the acute toxicity of chemicals on embryonic fish. Previous studies show a good correlation of FET with the standard acute fish toxicity (AFT) - however, the potential of FET test to predict AFT, which is required by the REACH Regulation (EC 1907/2006) and CLP (EC 1272/2008), has not yet been fully clarified. In 2015 the European Chemicals Agency (ECHA) requested a consultant to perform a scientific analysis on the applicability of FET to predict AFT...
December 11, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/29226222/learning-processes-and-learning-problems-in-german-postgraduate-medical-education
#11
Hendrik van den Bussche, Lea Krause-Solberg, Martin Scherer, Stine Ziegler
Objective: In order to evaluate the quality of postgraduate medical education in Germany, we examined how the learning of theoretical and practical competencies is conceptualized and how the learning process takes place in real terms. The training conditions, as perceived by medical residents, are compared with the learning objectives, as stated by the Federal Chamber of Physicians in its regulation on postgraduate education. The analysis is based on the data of the "KarMed" study (abbreviation of "career progression and career breaks among physicians during postgraduate education"), a multicentre cohort study of medical school graduates from seven universities who arre followed until they receive their licenses as specialist physicians...
2017: GMS Journal for Medical Education
https://www.readbyqxmd.com/read/29226166/a-radiographic-healing-classification-for-osteochondritis-dissecans-of-the-knee-provides-good-interobserver-reliability
#12
David E Ramski, Theodore J Ganley, James L Carey
Background: Recent studies have examined radiographic factors associated with healing of osteochondritis dissecans (OCD) lesions of the knee. However, there is still no gold standard in determining the healing status of an OCD lesion. Purpose: We examined temporally associated patterns of healing to (1) evaluate the practicality of a classification system and (2) elucidate any associations between healing pattern and patient age, sex, lesion location, treatment type, and physeal patency...
December 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29226163/diagnostic-accuracy-of-3-physical-examination-tests-in-the-assessment-of-hip-microinstability
#13
Daniel J Hoppe, Jeremy N Truntzer, Lauren M Shapiro, Geoffrey D Abrams, Marc R Safran
Background: Hip microinstability is a diagnosis gaining increasing interest. Physical examination tests to identify microinstability have not been objectively investigated using intraoperative confirmation of instability as a reference standard. Purpose: To determine the test characteristics and diagnostic accuracy of 3 physical examination maneuvers in the detection of hip microinstability. Study Design: Cohort study (diagnosis); Level of evidence, 2...
November 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29226106/elevated-liver-enzymes-in-asymptomatic-patients-what-should-i-do
#14
REVIEW
Mazyar Malakouti, Archish Kataria, Sayed K Ali, Steven Schenker
Elevated liver enzymes are a common scenario encountered by physicians in clinical practice. For many physicians, however, evaluation of such a problem in patients presenting with no symptoms can be challenging. Evidence supporting a standardized approach to evaluation is lacking. Although alterations of liver enzymes could be a normal physiological phenomenon in certain cases, it may also reflect potential liver injury in others, necessitating its further assessment and management. In this article, we provide a guide to primary care clinicians to interpret abnormal elevation of liver enzymes in asymptomatic patients using a step-wise algorithm...
December 28, 2017: Journal of Clinical and Translational Hepatology
https://www.readbyqxmd.com/read/29226041/dapagliflozin-cardiovascular-safety-and-benefits-in-type-2-diabetes-mellitus
#15
REVIEW
Fatima Saleem
Sodium-glucose co-transporter 2 inhibitors (SGLT2is) such as dapagliflozin, canagliflozin, and empagliflozin, are a promising new therapy in the treatment of type 2 diabetes mellitus (T2DM). SGLT2is can effectively reduce hyperglycemia thus improving glycemic control and they offer some beneficial effects on the cardiovascular (CV) system which can benefit patients with heart failure in addition toT2DM. The United States Food and Drug Administration requires new diabetes mellitus therapies to show a CV safety profile...
October 5, 2017: Curēus
https://www.readbyqxmd.com/read/29226019/absence-of-acanthocytosis-in-huntington-s-disease-like-2-a-prospective-comparison-with-huntington-s-disease
#16
David G Anderson, Sergio Carmona, Kubendran Naidoo, Theresa L Coetzer, Jonathan Carr, Dobrila D Rudnicki, Ruth H Walker, Russell L Margolis, Amanda Krause
Background: Huntington's Disease-like 2 (HDL2) is classified as a neuroacanthocytosis; however, this remains unverified. We aim to determine if acanthocytes are present in HDL2 and whether acanthocytes can differentiate HDL2 from Huntington's disease (HD). Methods: We prospectively compared 13 HD and 12 HDL2 cases against 21 unaffected controls in Johannesburg. Blood smears were prepared using international standards and reviewed by at least two blinded reviewers...
2017: Tremor and Other Hyperkinetic Movements
https://www.readbyqxmd.com/read/29225938/health-sector-governance-should-we-be-investing-more
#17
REVIEW
Robert Fryatt, Sara Bennett, Agnes Soucat
Governance is central to improving health sector performance and achieving Universal Health Coverage (UHC). However, the growing body of research on governance and health has not yet led to a global consensus on the need for more investment in governance interventions to improve health. This paper aims to summarise the latest evidence on the influence of governance on health, examines how we can assess governance interventions and considers what might constitute good investments in health sector governance in resource constrained settings...
2017: BMJ Global Health
https://www.readbyqxmd.com/read/29225808/symptom-burden-in-patients-with-chronic-kidney-disease-not-requiring-renal-replacement-therapy
#18
Stephanie A Brown, Freya C Tyrer, Amy L Clarke, Laetitia H Lloyd-Davies, Andrew G Stein, Carolyn Tarrant, James O Burton, Alice C Smith
Background: Although evidence shows that patients with end stage renal disease (ESRD) experience a high symptom burden which impacts on quality of life (QoL), less is known about patients with earlier stages of chronic kidney disease (CKD). This study aimed to explore symptom burden and potential contributing factors in patients with CKD Stage 1-5 not requiring renal replacement therapy (RRT). Methods: Patients with CKD Stage 1-5 and not on RRT were asked to report their symptoms using the Leicester Uraemic Symptom Score (LUSS), a questionnaire which assesses the frequency and intrusiveness of 11 symptoms commonly reported by kidney patients...
December 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29225797/seasonal-clustering-of-sinopulmonary-mucormycosis-in-patients-with-hematologic-malignancies-at-a-large-comprehensive-cancer-center
#19
Shobini Sivagnanam, Dhruba J Sengupta, Daniel Hoogestraat, Rupali Jain, Zach Stednick, David N Fredricks, Paul Hendrie, Estella Whimbey, Sara T Podczervinski, Elizabeth M Krantz, Jeffrey S Duchin, Steven A Pergam
Background: Invasive Mucorales infections (IMI) lead to significant morbidity and mortality in immunocompromised hosts. The role of season and climatic conditions in case clustering of IMI remain poorly understood. Methods: Following detection of a cluster of sinopulmonary IMIs in patients with hematologic malignancies, we reviewed center-based medical records of all patients with IMIs and other invasive fungal infections (IFIs) between January of 2012 and August of 2015 to assess for case clustering in relation to seasonality...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/29225688/repurposing-drugs-in-oncology-redo-chloroquine-and-hydroxychloroquine-as-anti-cancer-agents
#20
Ciska Verbaanderd, Hannelore Maes, Marco B Schaaf, Vikas P Sukhatme, Pan Pantziarka, Vidula Sukhatme, Patrizia Agostinis, Gauthier Bouche
Chloroquine (CQ) and hydroxychloroquine (HCQ) are well-known 4-aminoquinoline antimalarial agents. Scientific evidence also supports the use of CQ and HCQ in the treatment of cancer. Overall, preclinical studies support CQ and HCQ use in anti-cancer therapy, especially in combination with conventional anti-cancer treatments since they are able to sensitise tumour cells to a variety of drugs, potentiating the therapeutic activity. Thus far, clinical results are mostly in favour of the repurposing of CQ. However, over 30 clinical studies are still evaluating the activity of both CQ and HCQ in different cancer types and in combination with various standard treatments...
2017: Ecancermedicalscience
keyword
keyword
61718
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"