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Maxillofacial review

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https://www.readbyqxmd.com/read/27915980/molecular-cellular-and-pharmaceutical-aspects-of-synthetic-hydroxyapatite-bone-substitutes-for-oral-and-maxillofacial-grafting
#1
Werner Goetz, Spyridon N Papageorgiou
Bone grafts are widely used for augmentation procedures in oral and maxillofacial surgery, with autogenous bone being the gold standard. Recently, the focus of research has shifted towards synthetic bone substitutes, as no second surgery is needed and large quantities of graft can easily be provided. Within the broad range of bone substitutes, synthetic hydroxyapatite has drawn much attention, as they are considered to be biocompatible, non-immunogenic, osteoconductive and osteoinductive. Scope of this review is to summarize existing knowledge concerning the molecular, cellular and pharmaceutical aspects of synthetic bone substitutes for oral and maxillofacial grafting...
December 1, 2016: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/27899021/does-preoperative-diplopia-determine-the-incidence-of-postoperative-diplopia-after-repair-of-orbital-floor-fracture-an-institutional-review
#2
Avisham Ramphul, Gary Hoffman
PURPOSE: The purpose of our study was to investigate whether the occurrence of preoperative diplopia determines the incidence of postoperative diplopia after orbital floor repair. MATERIALS AND METHODS: We undertook a retrospective cohort study with a review of the records of 126 consecutive patients who had undergone repair of an orbital floor fracture under the maxillofacial surgery service at John Hunter Hospital (Newcastle, NSW, Australia). The primary predictor variables were a number of demographic, etiologic, and operative factors that might influence the occurrence of diplopia...
November 9, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27899019/antibiotic-resistance-in-severe-orofacial-infections
#3
Min Kyoung Kim, Sung-Kiang Chuang, Meredith August
PURPOSE: This study assessed the antibiotic resistance profile in patients with severe orofacial infections treated at a single institution from 2009 through 2014. Factors contributing to resistance were studied. The resistance profile was compared with that of a cohort of similar patients treated a decade previously to identify changes in antibiotic resistance. In addition, the effect of antibiotic resistance on in-hospital course was studied. MATERIALS AND METHODS: This was a 5-year retrospective cohort study...
November 9, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27895942/an-unusual-lacerated-tracheal-tube-during-le-fort-surgery-literature-review-and-case-report
#4
Preeta George, John E Fiadjoe, Allan F Simpao
Maxillofacial surgeries can present unique anesthetic challenges due to potentially complex anatomy and the close proximity of the patient's airway to the surgical field. Damage to the tracheal tube (TT) during maxillofacial surgery may lead to significant airway compromise. We report the management of a patient with a partially severed TT during Le Fort surgery for midfacial hypoplasia and management strategies based on peer-reviewed literature. This case illustrates the clinical clues associated with a damaged TT and explores the challenges of managing this potentially catastrophic issue...
2016: Case Reports in Anesthesiology
https://www.readbyqxmd.com/read/27889533/temporomandibular-joint-disorder-management-in-oral-and-maxillofacial%C3%A2-surgery
#5
Louis G Mercuri
PURPOSE: This article discusses why the management of temporomandibular joint disorder (TMD) cases leads to some oral and maxillofacial surgeons to actively avoid attracting such patients to their practices, offers some evidence-based explanations, and provides recommendations for resolution that will benefit not only the specialty but more importantly the patients it serves. MATERIALS AND METHODS: A review of the reasons some surgeons state they do not wish to manage TMD cases is presented, followed by an updated review of the TMD and orthopedic literature discussing not only the importance of a proper diagnosis but also the impact of comorbid conditions, genetics, clinical experience, and patient expectations important to achieving good TMD management outcomes...
November 4, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27866683/interventional-laser-surgery-for-oral-potentially-malignant-disorders-a-longitudinal-patient-cohort-study
#6
P J Thomson, M L Goodson, K Cocks, J E Turner
Oral squamous cell carcinoma (OSCC) is a lethal disease, with rising incidence. There were 6767 new OSCC cases and 2056 deaths in the UK in 2011. Cancers are preceded by oral potentially malignant disorders (PMDs), recognizable mucosal diseases harbouring increased SCC risk, offering clinicians a 'therapeutic window' to intervene. Contemporary practice remains unable to predict lesion behaviour or quantify malignant transformation risk. No clear management guidelines exist and it is unclear from the literature whether early diagnosis and intervention prevents cancer...
November 17, 2016: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27858082/-review-and-prospectives-of-oral-maxillofacial-surgery-in-the-world
#7
Xiao-Han Liu, Shan-Yong Zhang, Jia-Wei Zheng, Chi Yang
This article introduced the developing history and present status of oral and maxillofacial surgery in the world, with the aim to provide references for education of oral and maxillofacial surgery and further development.
August 2016: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/27856023/don-t-blow-it-extensive-subcutaneous-emphysema-of-the-neck-caused-by-isolated-facial-injuries-a-case-report-and-review-of-the-literature
#8
Hannah Makrides, Luke D Lawton
BACKGROUND: Although subcutaneous emphysema resulting from maxillofacial surgery is well described in the literature, the association with maxillofacial trauma is less firm. Clinically evident subcutaneous emphysema from facial injury is uncommon and extension into the cervical and mediastinal tissues is exceedingly rare, with few reported cases. CASE REPORT: An unusual case of extensive subcutaneous emphysema after facial trauma is presented. The case posed a diagnostic dilemma in our emergency department...
November 14, 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27846861/intraosseous-inflammatory-myofibroblastic-tumor-of-the-mandible-with-a-novel-atic-alk-fusion-mutation-a-case-report
#9
Yoko Tateishi, Koji Okudela, Shigeo Kawai, Takehisa Suzuki, Shigeaki Umeda, Mai Matsumura, Mitomu Kioi, Kenichi Ohashi
BACKGROUND: Inflammatory myofibroblastic tumor (IMT) is a rare low-grade malignant neoplasm with a predilection for children and young adults, and typically arises in the lung, abdominopelvic region, and retroperitoneum. IMTs in the maxillofacial region are extreme rare. Approximately 50% of IMT harbor rearrangements of the anaplastic lymphoma kinase (ALK) gene at 2p23 with various fusion partners. CASE PRESENTATION: We herein report a case of intraosseous IMT of the mandible with a novel ATIC-ALK fusion...
November 15, 2016: Diagnostic Pathology
https://www.readbyqxmd.com/read/27842482/antibiotic-release-from-calcium-phosphate-materials-in-oral-and-maxillofacial-surgery-molecular-cellular-and-pharmaceutical-aspects
#10
Angel Manchon, Juan Carlos Prados-Frutos, Carmen Rueda Rodriguez, Carmen Salinas Goodier, Mohammad Hadman Alkhraisat, Rosa Rojo, Arantza Rodriguez Gonzalez, Ana Berlanga, Enrique Lopez Cabarcos
Calcium phosphate materials (CPM) are widely used in dentistry and maxillofacial surgery. The presence of microbial biofilms and external infections are responsible for the failure of many procedures of dental implants and bone grafts. In an attempt to reduce the percentage of these infectious processes antibiotics have been associated with CPM improving certain conditions. For instance antibiotics administered orally or intravenously have less effect and the blood flow in relation to this is poor near implants and grafts...
November 14, 2016: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/27837346/the-effect-of-modified-surgical-flap-design-for-removal-of-lower-third-molars-on-lingual-nerve-injury
#11
Anwar B Bataineh, Ra'ad A Batarseh
AIM: The objective of this study was to evaluate a modified flap design for removal of lower third molars with avoidance of lingual flap elevation and its effect on postsurgical lingual nerve sensory impairment. MATERIALS AND METHODS: The patients included in this prospective study were those referred for removal of symptomatic lower third molars at two Oral and Maxillofacial Surgery clinics. Different patterns of impaction were included regarding the angulation and depth of the lower third molar...
November 12, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27833861/maxillofacial-infections-of-odontogenic-origin-epidemiological-microbiological-and-therapeutic-factors-in-an-indian-population
#12
V Yuvaraj
Odontogenic fascial space infections are commonly encountered by the oral and maxillofacial surgeon. A retrospective study of the epidemiological characteristics, microbiological analysis and treatment response to odontogenic infections treated in the oral and maxillofacial unit of a Dental school is presented. A retrospective analysis of case records of all odontogenic infections that reported to the oral and maxillofacial surgery unit in a Dental school over a period of 2 years was performed. Epidemiological data, microbiological profile and treatment responses were analysed...
December 2016: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/27833710/current-management-of-zygomaticomaxillary-complex-fractures-a-multidisciplinary-survey-and-literature-review
#13
Scott J Farber, Dennis C Nguyen, Gary B Skolnick, Albert S Woo, Kamlesh B Patel
Despite the prevalence of zygomaticomaxillary complex (ZMC) fractures, there is no consensus regarding the best approach to management. The aim of this study is to determine differences in ZMC fracture treatment among various surgical specialties. A survey was conducted regarding treatment of patients with different ZMC fractures that included a minimally displaced fracture (Case 1), a displaced fracture without diplopia (Case 2), a displaced fracture with diplopia (Case 3), and a complex comminuted fracture (Case 4)...
November 2016: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/27833346/open-access-publishing-a-study-of-current-practice-in-oral-and-maxillofacial-surgery-research
#14
Arpan Tahim, Hitesh Bansal, Alexander M C Goodson, Karl F B Payne, Sanjeeve Sabharwal
INTRODUCTION: Open access (OA) publication has become an increasingly common route for dissemination of scientific research findings. However, it remains a contentious issue with continued debate as to its impact on the peer-review process and a potential change in the quality of subsequent evidence published. There is little research that looks into OA in oral and maxillofacial surgery. METHODS: We investigated the OA policy in the 30 relevant journals listed in the Institute for Scientific Information Web of Knowledge journal citation report, comparing bibliometric data and quality of evidence produced in journals offering OA and those with subscription-only policies...
December 2016: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/27833333/zygomaticomaxillary-complex-fractures-a-review-of-101-cases
#15
Bhasker Yamsani, Rajasekhar Gaddipati, Nandagopal Vura, Sudhir Ramisetti, Rajitha Yamsani
AIM: ZMC fractures are the common facial injuries. The main causes of fractures are trauma due to RTAs, assaults, falls, sports related injuries, and the civilian warfares. This study is to evaluate and review the etiology, incidence, clinical findings and treatment of ZMC fractures. A sincere effort has been put forward in the management of ZMC fractures and their efficacy is evaluated in the larger interest of the patients. MATERIALS AND METHODS: In this study 101 patients having displaced ZMC fractures with insignificant medical history were reviewed to evaluate the versatility of its management, with the main emphasis on post operative stability, restoration of mouth opening, wound healing, esthetic restoration of the prominence of cheek and the complications encountered...
December 2016: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/27829740/induced-pluripotent-stem-cells-in-dentistry
#16
REVIEW
Paramel Mohan Sunil
Induced pluripotent stem cells (iPSCs), a path-breaking invention, have revolutionized the regenerative medicine field. The biggest advantage of this technology is its patient-specific nature and so it is nonimmunogenic. It involves autologous tissues with limitless source of cells throughout life. The Nobel-winning concept involves the reprograming of terminally differentiated cells by external factors and has a tremendous role in the treatment of genetic disorders, regeneration of tissues, drug discovery, and disease modeling...
October 2016: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/27823937/orbital-blowout-fractures-a-novel-computed-tomographic-measurement-that-can-predict-the-likelihood-of-surgical-management
#17
Tamer N Mansour, Megan Rudolph, Derek Brown, Natalie Mansour, M Reza Taheri
OBJECTIVE: The purpose of this study is to identify an accurate and reliable computed tomographic (CT) measurement that can identify those patients presenting to the emergency department (ED) with orbital floor fracture (BOF) who require surgical repair to prevent ensuing visually debilitating diplopia and/or enophthalmos. METHODS: In this retrospective institutional review board-approved study, we reviewed 99 patients older than 18 years with orbital fractures treated in a level I trauma center from 2011 through 2015...
October 14, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27819181/gene-therapy-for-bone-defects-in-oral-and-maxillofacial-surgery-a-systematic-review-and-meta-analysis-of-animal-studies
#18
Riham Fliefel, Jan Kühnisch, Michael Ehrenfeld, Sven Otto
Craniofacial bone defects are challenging problems for maxillofacial surgeons over the years. With the development of cell and molecular biology, gene therapy is a breaking new technology with the aim of regenerating tissues by acting as a delivery system for therapeutic genes in the craniofacial region rather than treating genetic disorders. A systematic review was conducted summarizing the articles reporting gene therapy in maxillofacial surgery to answer the question: Was gene therapy successfully applied to regenerate bone in the maxillofacial region? Electronic searching of online databases was performed in addition to hand-search of the references of the included articles...
November 7, 2016: Stem Cells and Development
https://www.readbyqxmd.com/read/27810548/immediate-transoral-allogeneic-bone-grafting-for-large-mandibular-defects-less-morbidity-more-bone-a-paradigm-in-benign-tumor-mandibular-reconstruction
#19
James C Melville, Nader N Nassari, Issa A Hanna, Jonathan W Shum, Mark E Wong, Simon Young
PURPOSE: Reconstruction of hard tissue continuity defects caused by ablative tumor surgery has been traditionally reconstructed with autogenous bone grafts or microvascular free flaps. Although results have been predictable from these 2 methods of reconstruction, the morbidity associated with bone harvest is quite serious for the patient. Predictable results have been obtained with using a combination of 100% cadaver bone, bone marrow aspirate concentrate (BMAC), and recombinant human bone morphogenic protein in immediate reconstruction for benign tumor extirpations through the extraoral approach...
October 6, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27798445/root-cause-analysis-an-examination-of-odontogenic-origins-of-acute-maxillary-sinusitis-in-both-immunocompetent-immunocompromised-patients
#20
Jennifer L McCarty, Ryan M David, Shelly Y Lensing, Rohan S Samant, Manoj Kumar, Rudy L Van Hemert, Edgardo J C Angtuaco, Ryan T Fitzgerald
BACKGROUND AND PURPOSE: Dental and periodontal diseases represent important but often overlooked causes of acute sinusitis. Our goal was to examine the prevalence of potential odontogenic sources of acute maxillary sinusitis according to immune status and their associations with sinusitis. MATERIALS AND METHODS: A retrospective review of maxillofacial computed tomography studies from 2013 to 2014 was performed. Each maxillary sinus and its ipsilateral dentition were evaluated for findings of acute sinusitis and dental/periodontal disease...
October 29, 2016: Journal of Computer Assisted Tomography
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