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Pre hospital glucose measurement

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https://www.readbyqxmd.com/read/28285650/plasma-hdl-cholesterol-and-triglycerides-but-not-ldl-cholesterol-are-associated-with-insulin-secretion-in-non-diabetic-subjects
#1
Andrea Natali, Simona Baldi, Fabrice Bonnet, John Petrie, Silvia Trifirò, Domenico Tricò, Andrea Mari
OBJECTIVE: Experimental data support the notion that lipoproteins might directly affect beta cell function, however clinical data are sparse and inconsistent. We aimed at verifying whether, independently of major confounders, serum lipids are associated with alterations in insulin secretion or clearance non-diabetic subjects. METHODS: Cross sectional and observational prospective (3.5yrs), multicentre study in which 1016 non-diabetic volunteers aged 30-60yrs. and with a wide range of BMI (20...
April 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28256812/severe-perioperative-hyperglycemia-attenuates-postoperative-monocytic-function-basophil-count-and-t-cell-activation
#2
Gunnar Lachmann, Clarissa von Haefen, Tobias Wollersheim, Claudia Spies
BACKGROUND: Hyperglycemia in hospitalized patients is associated with increased morbidity and mortality. Postoperative infections are particularly common in the setting of preoperative hyperglycemia; however, the relationship between perioperative glucose levels and the innate immune system remains unclear. METHODS: Immune cells, monocytic respectively T cell function and T cell subspecies of 32 patients after esophageal or pancreatic resection were analyzed preoperatively and on the first day after surgery (pod1)...
March 3, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28225315/improving-glycemic-control-safely-in-critical-care-patients-a-collaborative-systems-approach-in-nine-hospitals
#3
Gregory A Maynard, Janet Holdych, Heather Kendall, Karen Harrison, Patricia A Montgomery, Kristen Kulasa
Objective Safely improve glycemic control in the critical care units of nine hospitals. Methods Critical care adult inpatients from nine hospitals with ≥ 4 point-of-care (POC) blood glucose (BG) readings over ≥ 2 days were targeted by collaborative improvement efforts to reduce hyper- and hypo-glycemia. Balanced glucometric goals for each hospital were set targeting improvement from baseline, or goals deemed desirable from Society of Hospital Medicine (SHM) benchmarking data. Collaborative interventions included standardized insulin infusion protocols, hypoglycemia prevention bundles, audit and feedback, education, and measure-vention (coupling measurement of patients "off protocol" with concurrent interventions to correct suboptimal care)...
February 22, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28214752/metabolic-syndrome-and-cardiovascular-risk-among-institutionalized-patients-with-schizophrenia-receiving-long-term-tertiary-care
#4
Lee Seng Esmond Seow, Siow Ann Chong, Peizhi Wang, Saleha Shafie, Hui Lin Ong, Mythily Subramaniam
BACKGROUND: Metabolic syndrome (MetS) and cardiovascular risk are highly prevalent among individuals with schizophrenia. This study aimed to determine the cardiometabolic profile and the associated risk factors in a group of institutionalized patients with schizophrenia or schizoaffective disorder receiving prolonged hospital care in the only tertiary psychiatric institution in Singapore. METHODS: Patients residing in long stay wards who were hospitalized for a minimum period of 1year were recruited...
February 2, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28208930/precautionary-measures-for-successful-open-heart-surgery-in-g6pd-deficient-patient-a-case-report
#5
Rupesh Kumar
Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is among the most common enzymatic disorders of red blood cells. Cardiac surgeries on this group of individuals are associated with an additional risk in terms of impaired oxygenation, prolonged ventilation and increased risk of haemolysis. These patients have a very low threshold for haemolysis due to oxidative stress. Many commonly used drugs also predispose the individual for haemolysis when they are subjected to surgery. Here we present a known case of G6PD deficient patient with symptoms of breathlessness for the last nine years who was taken for surgery with pre-planned precautionary measures to avoid unnecessary haemolysis...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28144403/multimodality-functional-imaging-using-dw-mri-and-18-f-fdg-pet-ct-during-radiation-therapy-for-human-papillomavirus-negative-head-and-neck-squamous-cell-carcinoma-meixoeiro-hospital-of-vigo-experience
#6
David Aramburu Núñez, Antonio Lopez Medina, Moisés Mera Iglesias, Francisco Salvador Gomez, Abhay Dave, Vaios Hatzoglou, Ramesh Paudyal, Alfonso Calzado, Joseph O Deasy, Amita Shukla-Dave, Victor M Muñoz
AIM: To noninvasively investigate tumor cellularity measured using diffusion-weighted magnetic resonance imaging (DW-MRI) and glucose metabolism measured by (18)F-labeled fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG-PET/CT) during radiation therapy (RT) for human papillomavirus negative (HPV-) head and neck squamous cell carcinoma (HNSCC). METHODS: In this prospective study, 6 HPV- HNSCC patients underwent a total of 34 multimodality imaging examinations DW-MRI at 1...
January 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/28138182/gestational-diabetes-mellitus-and-the-predisposing-factors
#7
Syeda Sadia Fatima, Rehana Rehman, Faiza Alam, Sarosh Madhani, Bushra Chaudhry, Taseer Ahmed Khan
OBJECTIVE: To evaluate the occurrence of gestational diabetes mellitus and its association with demographic and anthropometric variables in pregnant women. METHODS: This cross-sectional study was conducted at the Aga Khan University Hospital, Abbasi Shaheed Hospital and Memon Hospital in Karachi, from February 2014 to December 2015, and comprised pregnant women who were screened by 75-g 2-hour oral glucose tolerance test, (24-28 weeks of gestation) and classified as per the criteria of the International Association of Diabetes and Pregnancy Study Group...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28005173/diabetes-education-of-patients-and-their-entourage-out-of-hospital-national-study-educated-2
#8
Frédéric Lapostolle, Nadia Hamdi, Majed Barghout, Louis Soulat, Anna Faucher, Yves Lambert, Nicolas Peschanski, Agnès Ricard-Hibon, Carine Chassery, Maryline Roti, Vincent Bounes, Guillaume Debaty, Tarak Mokni, Gérald Egmann, Pierre-Arnaud Fort, Karim Boudenia, Laurent Alayrac, Mohamed Safraou, Michel Galinski, Frédéric Adnet
AIMS: To determine the contributing factors in the successful diabetes education of patients and their entourage. METHODS: Prospective observational study conducted in a pre-hospital setting by 17 emergency services across France (September 2009-January 2011) included all insulin-treated patients (≥18 years) provided that at least one family member was present on scene. Data were collected from patients and their entourage: (1) personal details including language proficiency and educational attainment, (2) treatments, (3) diabetes-related data (log sheets, glucose meter, glucagon, glycated hemoglobin, prior hypoglycemic episodes); (4) care by diabetologist, general practitioner and/or visiting nurse...
December 22, 2016: Acta Diabetologica
https://www.readbyqxmd.com/read/27941737/challenges-in-hba1c-level-as-a-diagnostic-tool-of-diabetes-and-pre-diabetes-in-middle-aged-population-the-bangladesh-study
#9
A Begum, M A Muttalib, M N Arefin, M R Hoque, Z A Sheme, N Akter, U K Paul
Worldwide prevalence of diabetes is found to be the human health at an alarming rate. However, large numbers of patient remain undiagnosed. Oral glucose tolerance test (OGTT) still is regarded as gold standard in diagnosis of blood glucose abnormality. Although the less number of bodies are considering measurement of HbA1C as an alternate tool to identify risk group. This study was undertaken to evaluate the role of measurement of HbA1C in the diagnosis of diabetes and pre-diabetes in middle-aged Bangladeshi subjects and carried out in the department of Biochemistry, BIRDEM from July 2013 to June 2014...
October 2016: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/27921426/-gestational-diabetes-mellitus
#10
Hana Krejčí
The present generation of women of childbearing age more frequently suffer from overweight, obesity, initial as well as fully established metabolic syndrome, which together with postponing motherhood until the third decade in life plays an important role in the increasing incidence of gestational diabetes (GDM) that currently affects about 1/5 of pregnant women. However the causal link between diabetes during pregnancy and metabolic diseases in the whole population is mutual. By way of epigenetic changes, maternal diabetes unfavourably programmes metabolism of the offspring, who tend to transfer the disorder to the next generations...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27818228/computerized-insulin-order-sets-and-glycemic-control-in-hospitalized-patients
#11
Bertha Wong, Muhammad M Mamdani, Catherine H Yu
BACKGROUND: The purpose of this study was to evaluate the impact of computerized provider order entry subcutaneous insulin order sets on inpatient glycemic control and ordering behavior. METHODS: This was an interrupted time series study of non-intensive care patients at an urban teaching hospital. The primary outcome was proportion of capillary blood glucose in optimal range (4.0-10.0 mmol/L [72-180 mg/dL]) during the 6 months before and after a change to a computerized provider order entry-integrated insulin order set...
March 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/27800643/delivery-of-small-for-gestational-age-neonate-and-association-with-early-onset-impaired-maternal-endothelial-function
#12
S L Hillman, T Kubba, D J Williams
OBJECTIVE: Women who have delivered a small-for-gestational-age (SGA) infant are at an increased risk of developing cardiovascular disease (CVD) in later life. Endothelial dysfunction is a subclinical sign of early CVD. It is unknown whether women who have recently had a pregnancy complicated by SGA, in the absence of other maternal and fetal diseases, have subclinical endothelial dysfunction. Our aim was to assess maternal endothelial function 6 months after a pregnancy complicated by SGA...
January 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27753964/os-10-03-the-distinctive-effect-of-polysaccharide-peptides-ganoderma-lucidum-as-anti-atherogenesis-in-stable-angina-patients
#13
Nizamuddin Ubaidillah, Djanggan Sargowo, Adriawan Widya, Vitryaturrida Jakfar, Kartika Siwi Proboretno, Mirza Failasufi, Yoga Warahugraha, Fadli Ramadhan, Hesti Wulandari, Dinarsari Hayuning Putri
OBJECTIVE: This study was aimed to evaluate the effects of polysaccharide peptides (PsP) of Ganoderma lucidum as anti inflammation, anti oxidant, anti diabetic and anti lipid in stable angina pectoris patients. DESIGN AND METHOD: This is a quasi clinical trial experimental study on 34 Stable Angina patients in Saiful Anwar General Hospital was determined based on ESC Stable CAD guidelines, with pre-test and post-test design without control. Parameter measured were TNF alfa, IL-6, MDA, SOD, HbA1c, Fasting glucose and Total cholesterol...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27747467/gestational-diabetes-mellitus-its-association-with-obesity-a-prospective-cohort-study
#14
Reihaneh Pirjani, Nooshin Shirzad, Mostafa Qorbani, Mina Phelpheli, Ensieh Nasli-Esfahani, Fatemeh Bandarian, Mahboubeh Hemmatabadi
PURPOSE: The aim of this study was to investigate the association between pre-pregnancy body mass index (BMI) and gestational diabetes mellitus (GDM). METHODS: This prospective study was conducted on 256 pregnant women without diabetes referred for prenatal care in the first trimester of pregnancy to two referral University Hospitals (Shariati and Arash Hospitals) during the years 2012 and 2013. Eligible participants were selected consecutively and were followed until delivery and 6 weeks after that...
October 17, 2016: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/27746233/colon-hypersensitivity-to-distension-rather-than-excessive-gas-production-produces-carbohydrate-related-symptoms-in-individuals-with-irritable-bowel-syndrome
#15
Giles Major, Sue Pritchard, Kathryn Murray, Jan Paul Alappadan, Caroline L Hoad, Luca Marciani, Penny Gowland, Robin Spiller
BACKGROUND & AIMS: Poorly digested, fermentable carbohydrates may induce symptoms of irritable bowel syndrome (IBS) via unclear mechanisms. We performed a randomized trial with magnetic resonance imaging (MRI) analysis to investigate correlations between symptoms and changes in small- and large-bowel contents after oral challenge. METHODS: We performed a 3-period, cross-over study of 29 adult patients with IBS (based on Rome III criteria, with symptoms of abdominal pain or discomfort for at least 2 days/wk) and reported bloating...
January 2017: Gastroenterology
https://www.readbyqxmd.com/read/27709794/addition-of-a-dipeptidyl-peptidase-4-inhibitor-sitagliptin-to-ongoing-therapy-with-the-glucagon-like-peptide-1-receptor-agonist-liraglutide-a-randomized-controlled-trial-in-patients-with-type-2-diabetes
#16
Michael A Nauck, Melanie Kahle, Oleg Baranov, Carolyn F Deacon, Jens J Holst
AIM: To determine whether the addition of sitagliptin to pre-existing therapy with liraglutide changes glycaemic excursions after a mixed meal. METHODS: A total of 16 patients with type 2 diabetes treated with metformin and liraglutide (1.2 mg/d for ≥2 weeks) were randomized (sealed envelopes), within a cross-over design, to be studied on two occasions, after an overnight fast, with (1) sitagliptin (100 mg orally) and (2) placebo (patients and care givers blinded) administered 60 minutes before a mixed meal, or vice versa...
October 6, 2016: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/27643361/os-10-03-the-distinctive-effect-of-polysaccharide-peptides-ganoderma-lucidum-as-anti-atherogenesis-in-stable-angina-patients
#17
Nizamuddin Ubaidillah, Djanggan Sargowo, Adriawan Widya, Vitryaturrida Jakfar, Kartika Siwi Proboretno, Mirza Failasufi, Yoga Warahugraha, Fadli Ramadhan, Hesti Wulandari, Dinarsari Hayuning Putri
OBJECTIVE: This study was aimed to evaluate the effects of polysaccharide peptides (PsP) of Ganoderma lucidum as anti inflammation, anti oxidant, anti diabetic and anti lipid in stable angina pectoris patients. DESIGN AND METHOD: This is a quasi clinical trial experimental study on 34 Stable Angina patients in Saiful Anwar General Hospital was determined based on ESC Stable CAD guidelines, with pre-test and post-test design without control. Parameter measured were TNF alfa, IL-6, MDA, SOD, HbA1c, Fasting glucose and Total cholesterol...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27540877/hypoglycemia-rates-after-restriction-of-high-dose-glargine-in-hospitalized-patients
#18
Sun Y Lee, Gulce Askin, Marie E McDonnell, Lindsay M Arnold, Sara M Alexanian
OBJECTIVE: Hypoglycemia remains one of the main challenges of insulin therapy. To reduce insulin-related hypoglycemia at our institution, we restricted inpatient ordering of high glargine doses (≥0.5 U/kg/day) to endocrine staff in May 2013. This retrospective cohort study assesses its effect on hypoglycemia and glycemic control within 48 hours of admission (ADM). METHODS: We identified 692 adult patients hospitalized at Boston Medical Center who received glargine upon ADM from November 1, 2012 through April 30, 2013 as the pre-intervention group, and 651 adult patients admitted between November 1, 2013 and April 30, 2014 as the postintervention group...
December 2016: Endocrine Practice
https://www.readbyqxmd.com/read/27465014/factors-associated-with-duration-of-inpatient-hospital-stay-for-patients-with-diabetes-mellitus-admitted-to-a-medical-unit-in-a-community-public-hospital
#19
Melissa H Lee, Lillianne Liprino, Jeffrey Brooks, Brenda Cayzer, Fiona Weedon, Kate Bermingham, Alicia J Jenkins, Kevin Rowley, David N O'Neal
The aim was to examine predictors of duration of inpatient hospital stay in people with diabetes mellitus to assist implementation of strategies to reduce hospital stay. This audit prospectively studied patients with diabetes mellitus admitted to a medical unit of an Australian community public hospital. Other outcome measures included glucose treatment optimisation and access to GP and diabetes-specific healthcare professionals. Comparison was made to patients without diabetes mellitus who were admitted concomitantly...
July 28, 2016: Australian Journal of Primary Health
https://www.readbyqxmd.com/read/27324989/brain-derived-neurotrophic-factor-impaired-glucose-metabolism-and-bipolar-disorder-course
#20
Rodrigo B Mansur, Camila M Santos, Lucas B Rizzo, Elson Asevedo, Graccielle R Cunha, Mariane N Noto, Mariana Pedrini, Maiara Zeni-Graiff, Quirino Cordeiro, Maj Vinberg, Flavio Kapczinski, Roger S McIntyre, Elisa Brietzke
OBJECTIVES: The neurotrophin brain-derived neurotrophic factor (BDNF) has been proposed as a potential biomarker in bipolar disorder (BD). However, current evidence is limited and results have been highly heterogeneous. This study aimed to assess the moderating effect of impaired glucose metabolism (IGM) on plasma levels of BDNF in individuals with BD, and on the relationship between BDNF and variables of illness course. METHODS: We measured and compared the plasma levels of BDNF in individuals with BD (n=57) and healthy controls (n=26)...
June 2016: Bipolar Disorders
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