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(Knee osteoarthritis) AND (physical activity)

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https://www.readbyqxmd.com/read/28068480/magnetic-resonance-imaging-characterization-and-clinical-outcomes-after-neocart-surgical-therapy-as-a-primary-reparative-treatment-for-knee-cartilage-injuries
#1
Devon E Anderson, Riley J Williams, Thomas M DeBerardino, Dean C Taylor, C Benjamin Ma, Marie S Kane, Dennis C Crawford
BACKGROUND: Autologous cartilage tissue implants, including the NeoCart implant, are intended to repair focal articular cartilage lesions. Short-term results from United States Food and Drug Administration (FDA) phase I and phase II clinical trials indicated that the NeoCart implant was safe when surgically applied as a cell-based therapy and efficacious compared with microfracture. HYPOTHESIS: Quantitative magnetic resonance imaging (MRI) analysis would reveal NeoCart tissue maturation through to 60-month follow-up...
January 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28056178/is-there-any-benefit-in-anterior-cruciate-ligament-reconstruction-in-patients-older-than-60-years
#2
Cécile Toanen, Guillaume Demey, Panagiotis G Ntagiopoulos, Paolo Ferrua, David Dejour
BACKGROUND: Results of anterior cruciate ligament (ACL) reconstruction are traditionally excellent in younger and nonarthritic patients. During the past few decades, people older than 60 years have become more active than ever, with more demanding physical lifestyles. An increase also has been noted in active patients with diagnosed ACL injuries. More patients are requesting treatment for ACL deficiency in hopes of returning to preinjury levels of activity. PURPOSE: The aims of this study were to evaluate the results of ACL reconstruction in patients older than 60 years in terms of functional recovery, return to sports, and postoperative incidence of osteoarthritis and to compare their results with published results of different age groups...
December 1, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28051248/movardol%C3%A2-n-acetylglucosamine-boswellia-serrata-ginger-supplementation-in-the-management-of-knee-osteoarthritis-preliminary-results-from-a-6-month-registry-study
#3
G Bolognesi, G Belcaro, B Feragalli, U Cornelli, R Cotellese, S Hu, M Dugall
OBJECTIVE: Knee Osteoarthritis (OA) is a chronic disease caused by the deterioration of cartilage in joints, which results in activation of the inflammatory response, pain, and impaired movement. Complementary therapies, particularly supplementation, in the management of moderate/severe knee OA have been gaining attention. This registry study aimed at evaluating the synergistic effect of Movardol®, a supplementation containing active ingredients with recognized anti-inflammatory activities on symptoms and levels of circulating biomarkers of knee OA...
December 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28038881/green-tea-camellia-sinensis-for-patients-with-knee-osteoarthritis-a-randomized-open-label-active-controlled-clinical-trial
#4
Mohammad Hashem Hashempur, Sara Sadrneshin, Seyed Hamdollah Mosavat, Alireza Ashraf
BACKGROUND: Green tea is known as a dietary supplement and a novel functional food worldwide. Since there are increasing preclinical evidence about efficacy of green tea for treating osteoarthritis, this study has aimed at assessing its efficacy and safety for patients with knee osteoarthritis. METHODS: This is a randomized open-label active-controlled clinical trial. As many as fifty adults with osteoarthritis of knee were randomly allocated to receive the green tea extract (in dosage form of tablet) plus diclofenac tablet as "intervention group"; or: diclofenac tablet alone as "control group" for a period of four weeks...
December 18, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28038376/lean-muscle-volume-of-the-thigh-has-a-stronger-relationship-with-muscle-power-than-muscle-strength-in-women-with-knee-osteoarthritis
#5
Michael J Davison, Monica R Maly, Peter J Keir, Sandani M Hapuhennedige, Amie T Kron, Jonathan D Adachi, Karen A Beattie
BACKGROUND: Thigh lean muscle and intramuscular fat have been implicated in the impairment of physical function observed in people with knee osteoarthritis. We investigated the relationships of quadriceps and hamstrings intramuscular fat fraction and lean muscle volume with muscle power and strength, controlling for neuromuscular activation, and physical performance in women with knee OA. METHODS: Women (n=20) 55years or older with symptomatic, radiographic knee osteoarthritis underwent a 3...
November 25, 2016: Clinical Biomechanics
https://www.readbyqxmd.com/read/28035445/effect-of-progressive-high-impact-exercise-on-femoral-neck-structural-strength-in-postmenopausal-women-with-mild-knee-osteoarthritis-a-12-month-rct
#6
J Multanen, T Rantalainen, H Kautiainen, R Ahola, T Jämsä, M T Nieminen, E Lammentausta, A Häkkinen, I Kiviranta, A Heinonen
: It is uncertain whether subjects with mild knee osteoarthritis, and who may be at risk of osteoporosis, can exercise safely with the aim of improving hip bone strength. This RCT showed that participating in a high-impact exercise program improved femoral neck strength without any detrimental effects on knee cartilage composition. INTRODUCTION: No previous studies have examined whether high-impact exercise can improve bone strength and articular cartilage quality in subjects with mild knee osteoarthritis...
December 29, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/28034979/efficacy-and-safety-of-tanezumab-on-osteoarthritis-knee-and-hip-pains-a-meta-analysis-of-randomized-controlled-trials
#7
Junyuan Chen, Jieruo Li, Ruobin Li, Huajun Wang, Jie Yang, Jichun Xu, Zhengang Zha
OBJECTIVES:  To evaluate the efficacy and safety of tanezumab for management of osteoarthritis (OA) knee and hip pain. METHODS:  Articles about management of OA knee and hip pains by tanezumab were systematically searched in PubMed, EBSCO, EMBASE, ScienceDirect, Web of Science, OVID, and Cochrane Library from the available date of inception until January 2016. Randomized controlled trials (RCTs) comparing the efficacy and safety of tanezumab with placebo/active comparator for management of OA knee and hip pains were included, and those with confounding conditions were excluded...
December 29, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28034720/qualitative-development-of-a-discrete-choice-experiment-for-physical-activity-interventions-to-improve-knee-osteoarthritis
#8
Daniel Pinto, Margaret Danilovich, Paul Hansen, Daniel J Finn, Rowland W Chang, Jane L Holl, Allen W Heinemann, Ulf Bockenholt
OBJECTIVE: To describe the qualitative process used to develop attributes and attribute levels for inclusion in a discrete choice experiments (DCE) for older adult physical activity interventions. DESIGN: Five focus groups (a total of 41 participants) were conducted, grounded in the Health Action Process Approach framework. Discussion emphasized identification and prioritization attributes for a DCE on physical activity. Semi-structured interviews (n=6) investigated attribute levels and lay-language for the DCE...
December 27, 2016: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28031495/risk-factors-for-fear-of-falling-in-elderly-patients-with-severe-knee-osteoarthritis-before-and-one-year-after-total-knee-arthroplasty
#9
Theano Tsonga, Maria Michalopoulou, Stylianos Kapetanakis, Eirini Giovannopoulou, Paraskevi Malliou, George Godolias, Panagiotis Soucacos
PURPOSE: To evaluate the regression of fear of falling (FOF) and identify its risk factors in patients with severe knee osteoarthritis before and one year after total knee arthroplasty (TKA). METHODS: 11 men and 57 women with a mean age of 73 years and a mean body mass index of 30.36 kg/m2 who had severe (grade 3 or 4) knee osteoarthritis and knee pain of ≥1 year were included. Two weeks before and one year after TKA, patients were asked about their FOF status and falls history...
December 2016: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28029748/physical-activity-minimum-threshold-predicting-improved-function-in-adults-with-lower-limb-symptoms
#10
Dorothy D Dunlop, Jing Song, Jungwha Lee, Abigail L Gilbert, Pamela A Semanik, Linda Ehrlich-Jones, Christine A Pellegrini, Daniel Pinto, Barbara Ainsworth, Rowland W Chang
OBJECTIVES: The objective is to identify an evidence-based minimum physical activity threshold to predict improved or sustained high function for adults with lower limb joint symptoms. METHODS: Prospective multi-site data from 1629 adults aged 49 years or older with symptomatic lower limb joint pain/aching/stiffness participating in Osteoarthritis Initiative accelerometer monitoring substudy were clinically assessed two years apart. Improved/high function in 2-year gait speed and patient-reported outcomes (PRO) were based on improving or remaining in the best (i...
December 28, 2016: Arthritis Care & Research
https://www.readbyqxmd.com/read/28028570/comparable-outcomes-after-total-knee-arthroplasty-in-patients-under-55%C3%A2-years-than-in-older-patients-a-matched-prospective-study-with-minimum-follow-up-of-10%C3%A2-years
#11
Alejandro Lizaur-Utrilla, Daniel Martinez-Mendez, Francisco A Miralles-Muñoz, Luis Marco-Gómez, Fernando A Lopez-Prats
PURPOSE: To compare outcomes after TKA for osteoarthritis between patients younger than 55 years and older patients. METHODS: A cohort of 61 patients aged 55 years or younger was prospectively matched for gender, body mass index and knee function with patients with median age of 66 (range 60-70) years. Clinical evaluation was performed by the Knee Society scores (KSS), reduced Western Ontario and McMasters Universities (WOMAC) and Short-Form 12 (SF12) questionnaires...
December 27, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28017942/-physical-activity-for-knee-osteoarthritis
#12
Masashi Nagao, Muneaki Ishijima, Haruka Kaneko, Yuji Takazawa, Hiroshi Ikeda, Kazuo Kaneko
Elder populations have been increasing in Japan and estimated 24 million people have knee osteoarthritis(OA). Recently, people have diverse sociological background and demand for participating sports has been growing. People may participate sports to prevent some diseases such as locomotive syndrome. According to the recent studies, excessive high impact sports increase the risk of OA, while daily life exercise decrease the risk. Epidemiological approach demonstrated that reduced knee extension muscle strength increases the risk of OA...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28011099/a-walking-program-for-people-with-severe-knee-osteoarthritis-did-not-reduce-pain-but-may-have-benefits-for-cardiovascular-health-a-phase-ii-randomised-controlled-trial
#13
J A Wallis, K E Webster, P Levinger, P J Singh, C Fong, N F Taylor
OBJECTIVE: The primary aim was to evaluate the effect of a dosed walking program on knee pain for patients with severe knee osteoarthritis (OA). Secondary aims evaluated the effects on cardiovascular health, function and quality of life. DESIGN: Participants with severe knee OA and increased cardiovascular risk were randomly assigned to a 12-week walking program of 70 min/week of at least moderate intensity, or to usual care. The primary outcome was knee pain (0-10)...
December 20, 2016: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28009632/anti-nerve-growth-factor-therapy-increases-spontaneous-day-night-activity-in-mice-with-orthopedic-surgery-induced-pain
#14
Lisa A Majuta, Jean-Marc G Guedon, Stefanie A T Mitchell, Michael H Ossipov, Patrick W Mantyh
Total knee arthroplasty (TKA) and total hip arthroplasty (THA) are two of the most common and successful surgical interventions to relieve osteoarthritis pain. Control of postoperative pain is critical for patients to fully participate in the required physical therapy which is the most influential factor in effective postoperative knee rehabilitation. Currently opiates are a mainstay for managing postoperative orthopedic surgery pain including TKA/THA pain. Recently, issues including efficacy, dependence, overdose and death from opiates have made clinicians and researchers more critical of use of opioids for treating non-malignant skeletal pain...
December 15, 2016: Pain
https://www.readbyqxmd.com/read/28003302/cost-effectiveness-of-early-surgery-versus-conservative-treatment-with-optional-delayed-meniscectomy-for-patients-over-45%C3%A2-years-with-non-obstructive-meniscal-tears-escape-study-protocol-of-a-randomised-controlled-trial
#15
Victor A van de Graaf, Vanessa A B Scholtes, Nienke Wolterbeek, Julia C A Noorduyn, Camille Neeter, Maurits W van Tulder, Daniël B F Saris, Arthur de Gast, Rudolf W Poolman
INTRODUCTION: Recent studies show similar outcome between surgery and conservative treatment in patients with non-obstructive meniscal tears. However, surgery is still often preferred over conservative treatment. When conservative treatment is non-inferior to surgery, shifting the current standard treatment choice to conservative treatment alone could save over €30 millions of direct medical costs on an annual basis. Economic evaluation studies comparing surgery to conservative treatment are lacking...
December 21, 2016: BMJ Open
https://www.readbyqxmd.com/read/28002153/do-inactive-older-adults-who-increase-physical-activity-experience-less-disability-evidence-from-the-osteoarthritis-initiative
#16
Jing Song, Abigail L Gilbert, Rowland W Chang, Christine A Pellegrini, Linda S Ehrlich-Jones, Jungwha Lee, Daniel Pinto, Pamela A Semanik, Leena Sharma, C Kent Kwoh, Rebecca D Jackson, Dorothy D Dunlop
BACKGROUND: Physical inactivity is a leading risk factor for developing disability. Although randomized clinical trials have demonstrated improving physical activity can reduce this risk in older adults with arthritis, these studies did not specifically evaluate inactive adults. OBJECTIVES: The aim of this study was to evaluate the relationship of changes in physical activity with disability changes among initially inactive adults with or at high risk of knee osteoarthritis from Osteoarthritis Initiative...
January 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/27998033/current-physical-activity-monitors-in-hip-and-knee-osteoarthritis-a-review
#17
REVIEW
Maik Sliepen, Mirko Brandes, Dieter Rosenbaum
OBJECTIVE: To provide an up-to-date overview of physical activity monitors that are being/have been used within hip and knee osteoarthritis research. METHODS: A review was conducted to identify activity monitors used in hip and knee osteoarthritis research. In order to identify the relevant literature to-date, the MEDLINE (via Pubmed), EMBASE (via OVID) and SCOPUS databases were searched from January 2000 until January 2016. Per activity monitor, a broad range of specifications was identified by extracting information from the manufacturers' websites, device manuals and literature...
December 20, 2016: Arthritis Care & Research
https://www.readbyqxmd.com/read/27984493/anti-nerve-growth-factor-therapy-increases-spontaneous-day-night-activity-in-mice-with-orthopedic-surgery-induced-pain
#18
Lisa A Majuta, Jean-Marc G Guedon, Stefanie A T Mitchell, Michael H Ossipov, Patrick W Mantyh
Total knee arthroplasty (TKA) and total hip arthroplasty (THA) are two of the most common and successful surgical interventions to relieve osteoarthritis pain. Control of postoperative pain is critical for patients to fully participate in the required physical therapy which is the most influential factor in effective postoperative knee rehabilitation. Currently opiates are a mainstay for managing postoperative orthopedic surgery pain including TKA/THA pain. Recently, issues including efficacy, dependence, overdose and death from opiates have made clinicians and researchers more critical of use of opioids for treating non-malignant skeletal pain...
December 15, 2016: Pain
https://www.readbyqxmd.com/read/27942148/the-effects-of-high-intensity-laser-therapy-on-pain-and-function-in-patients-with-knee-osteoarthritis
#19
Gook-Joo Kim, Jioun Choi, Sangyong Lee, Chunbae Jeon, Kwansub Lee
[Purpose] The purpose of this study was to examine the effects of high intensity laser therapy (HILT) on pain and function in patients with knee osteoarthritis. [Subjects and Methods] In this study, an experiment was conducted on 20 subjects who were divided into the control group (n=10), which would receive conservative physical therapy (CPT), and the experimental group (n=10), which would receive effects of high intensity laser therapy after conservative physical therapy. All patients received their respective therapies three times each week over a four-week period...
November 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/27939623/factors-associated-with-meniscal-body-extrusion-on-knee-mri-in-overweight-and-obese-women
#20
F Zhang, S M Bierma-Zeinstra, E H G Oei, A Turkiewicz, M Englund, J Runhaar
OBJECTIVE: To determine factors associated with higher degree of meniscal body extrusion in overweight and obese women at high risk of knee osteoarthritis (OA). DESIGN: We used baseline data of the PRevention of knee Osteoarthritis in Overweight Females (PROOF) study, Netherlands, comprising overweight or obese women aged 50-60 years, free of clinical knee OA. All subjects completed a questionnaire on knee complaints and physical activity, underwent physical examination, radiography, and 1...
December 7, 2016: Osteoarthritis and Cartilage
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