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Posterior vitreous detachment

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https://www.readbyqxmd.com/read/29146307/long-term-visual-outcomes-and-safety-profile-of-27-gauge-pars-plana-vitrectomy-for-posterior-segment-disease
#1
M Ali Khan, Alexander Kuley, Christopher D Riemann, Maria H Berrocal, Rohit R Lakhanpal, Jason Hsu, Arunan Sivalingam, Allen C Ho, Carl D Regillo
PURPOSE: To report longer-term outcomes of 27-gauge pars plana vitrectomy (PPV) in eyes with posterior segment disease. DESIGN: Multicenter, retrospective, interventional case series. PARTICIPANTS: A total of 390 eyes of 360 patients undergoing 27-gauge PPV for a vitreoretinal surgery indication. INTERVENTION: Three-port, transconjunctival, 27-gauge PPV. MAIN OUTCOME MEASURES: Change in visual acuity (VA) and occurrence of intraoperative and postoperative complications with a minimum follow-up of 365 days...
November 13, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29146306/real-world-vision-in-age-related-macular-degeneration-patients-treated-with-single-anti-vegf-drug-type-for-1-year-in-the-iris-registry
#2
Prethy Rao, Flora Lum, Kevin Wood, Craig Salman, Bhavya Burugapalli, Rebecca Hall, Sukhminder Singh, David W Parke, George A Williams
PURPOSE: The purpose of this study is to compare real-world visual acuity (VA) in patients with neovascular age-related macular degeneration (nAMD) treated with a single anti-vascular endothelial growth factor (VEGF) drug monotherapy for 1 year from the American Academy of Ophthalmology (AAO) Intelligent Research in Sight (IRIS) Registry. DESIGN: Retrospective, nonrandomized, comparative study. PARTICIPANTS: IRIS Registry patients with nAMD who received bevacizumab, ranibizumab, or aflibercept only for 1 year between 2013-2016...
November 13, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29141386/-clinical-characteristics-and-surgical-effect-observation-of-congenital-aniridia-combined-with-cataract
#3
X H Wu, Q Z Cao, Y X Hu, J N Lin, H T Lin, W R Chen, Y Z Liu
Objective: To analyze the clinical manifestations, surgical approaches and postoperative prognosis for the cases of congenital aniridia combined with cataract. Methods: In this retrospective case series, 26 patients diagnosed with congenital aniridia combined with cataract were collected from Zhongshan Ophthalmic Center from February 2002 to August 2016. The Clinical data were collected to analyze the clinical features, surgical approaches and postoperative prognosis. T-test was used for statistical analysis...
November 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29133644/stenotrophomonas-maltophilia-an-emerging-entity-for-cluster-endophthalmitis
#4
Sarita Beri, Anurag Shandil, Rajiv Garg
PURPOSE: This was a study of acute cluster endophthalmitis along with clinical features, culture results, and visual outcomes of 10 eyes of 10 patients after intravitreal injection of Avastin (bevacizumab) in one sitting from a single vial. METHODS: Retrospective review of intravitreal injection of 1.25 mg/0.05 ml bevacizumab that was given to 10 eyes of 10 patients on the same day from a freshly opened vial. All patients manifested with endophthalmitis the next day...
November 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29130626/age-related-macular-degeneration-using-morphological-predictors-to-modify-current-treatment-protocols
#5
REVIEW
Mohammed Ashraf, Ahmed Souka, Ron A Adelman
To assess predictors of treatment response in neovascular age-related macular degeneration (AMD) in an attempt to develop a patient-centric treatment algorithm. We conducted a systematic search using PubMed, EMBASE and Web of Science for prognostic indicators/predictive factors with the key words: 'age related macular degeneration', 'neovascular AMD', 'choroidal neovascular membrane (CNV)', 'anti-vascular endothelial growth factor (anti-VEGF)', 'aflibercept', 'ranibizumab', 'bevacizumab', 'randomized clinical trials', 'post-hoc', 'prognostic', 'predictive', 'response' 'injection frequency, 'treat and extend (TAE), 'pro re nata (PRN)', 'bi-monthly' and 'quarterly'...
November 11, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29109894/vitreomacular-interface-disorders-in-beh%C3%A3-et-s-uveitis
#6
Hilal Eser Öztürk, Özlem Eşki Yücel, Yüksel Süllü
Objectives: To determine the prevalence of vitreomacular interface (VMI) disorders in patients with Behçet's uveitis and assess the relationship between VMI disorders and clinical characteristics. Materials and Methods: The macular optical coherence tomography (OCT) images of 160 eyes of 96 patients with Behçet's uveitis who were being followed in the Uvea-Behçet's clinic were assessed retrospectively for VMI disorders including posterior vitreous detachment (PVD), epiretinal membrane (ERM), vitreomacular adhesion (VMA), vitreomacular traction (VMT), full-thickness macular hole (FTMH), lamellar hole (LH) and pseudohole...
October 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29075095/posterior-vitreous-detachment-prevalence-of-and-risk-factors-for-retinal-tears
#7
Martin Bond-Taylor, Gunnar Jakobsson, Madeleine Zetterberg
PURPOSE: The present study aimed to describe clinical characteristics of patients with posterior vitreous detachment (PVD), to determine the prevalence of retinal tears in PVD patients, and to find predictors for retinal tears in this patient group. METHODS: Retrospective analysis of medical records on patients diagnosed with PVD, retinal tears, or vitreous hemorrhage at the Department of Ophthalmology at Sahlgrenska University Hospital, a tertiary eye center. RESULTS: Between February and July 2009, 365 patients consulted the Department of Ophthalmology for PVD-related symptoms...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29071469/ultrastructural-analyses-of-internal-limiting-membrane-excised-from-highly-myopic-eyes-with-myopic-traction-maculopathy
#8
Reiji Yokota, Akito Hirakata, Nobutsugu Hayashi, Kazunari Hirota, Tosho Rii, Yuji Itoh, Tadashi Orihara, Makoto Inoue
PURPOSE: To evaluate the ultrastructure of the internal limiting membranes (ILMs) excised during vitrectomy from highly myopic eyes with myopic traction maculopathy (MTM). The clinical findings before and after the vitrectomy were compared. METHODS: Seven eyes of 7 patients with macular retinoschisis were studied. Four of these eyes also had a foveal detachment but without a retinal break. All the eyes underwent vitrectomy with the creation of a posterior vitreous detachment and ILM peeling...
October 25, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29063741/optic-nerve-head-hemorrhages-associated-with-posterior-vitreous-detachment
#9
Philip J Polkinghorne
PURPOSE: To report and evaluate the clinical and optical coherence tomography (OCT) features of optic nerve hemorrhages (ONH) associated with spontaneous posterior vitreous detachment (PVD). DESIGN: A prospective case series conducted at a private ophthalmic practice in Auckland, New Zealand. METHODS: A consecutive series of patients presenting at a private multispecialty practice in Auckland, New Zealand, with symptoms of PVD with ONH underwent imaging of the optic nerve with digital retinal photography and OCT...
October 24, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/29042095/can-emergency-physicians-accurately-distinguish-retinal-detachment-from-posterior-vitreous-detachment-with-point-of-care-ocular-ultrasound
#10
Nicola Baker, Richard Amini, Elaine H Situ-LaCasse, Josie Acuña, Tomas Nuño, Uwe Stolz, Srikar Adhikari
STUDY OBJECTIVE: There is significant overlap between the symptoms of patients presenting with retinal detachment (RD) and posterior vitreous detachment (PVD). Urgency to obtain consultation and treatment are dependent on the ability to accurately distinguish these two conditions. The objective of this study was to determine the ability of emergency physicians to differentiate RDs from PVDs using point-of-care (POC) ocular ultrasound. METHODS: Single blinded cross-sectional study at an academic medical center...
October 13, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29040800/ocriplasmin-for-symptomatic-vitreomacular-adhesion
#11
REVIEW
James E Neffendorf, Varo Kirthi, Edward Pringle, Timothy L Jackson
BACKGROUND: Symptomatic vitreomacular adhesion (sVMA) is a recognised cause of visual loss and by tradition has been managed by pars plana vitrectomy (PPV). A less invasive alternative to surgery in some people is enzymatic vitreolysis, using an intravitreal injection of ocriplasmin. OBJECTIVES: To assess the efficacy and safety of ocriplasmin compared to no treatment, sham or placebo for the treatment of sVMA. SEARCH METHODS: We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (which contains the Cochrane Eyes and Vision Trials Register) (2017, Issue 1), MEDLINE Ovid (1946 to 24 February 2017), Embase Ovid (1947 to 24 February 2017), PubMed (1946 to 24 February 2017), the ISRCTN registry (www...
October 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29022285/macular-hole-development-after-vitrectomy-for-floaters-a-case-report
#12
Andrea Appeltans, Marco Mura, Giulio Bamonte
INTRODUCTION: The purpose of this report is to describe a case of macular hole development after vitrectomy for floaters with induction of posterior vitreous detachment. CASE REPORT: A 44-year-old otherwise healthy man presented with visually debilitating floaters in his right eye; these had been present for more than 2 years. Preoperative examination was unremarkable in both eyes, apart from some degree of vitreous degeneration in the right eye. Preoperative visual acuity was 20/20 bilaterally...
December 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28985803/flashes-and-floaters-a-survey-of-canadian-ophthalmology-residents-practice-patterns
#13
Parnian Arjmand, Bernard Hurley
BACKGROUND: Residents are often the first point of contact in assessing patients who present with "flashes and floaters" in the emergency ophthalmology clinic. Most often, these symptoms are attributed to a posterior vitreous detachment (PVD), which may be associated with a retinal tear in up to 14% of cases. A proper peripheral retinal exam is, thus, imperative, and techniques other than scleral depression may not be sufficient. We conducted a cross-sectional survey of Canadian ophthalmology residents-in-training to understand the current resident practice patterns for examination of the peripheral retina...
October 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28979089/long-term-evaluation-of-spontaneous-release-of-epiretinal-membrane-and-its-possible-pathogenesis
#14
Teruyo Kida, Seita Morishita, Masanori Fukumoto, Takaki Sato, Hidehiro Oku, Tsunehiko Ikeda
PURPOSE: To investigate the characteristics in spontaneous release of epiretinal membrane (ERM) during watchful waiting and to introduce a possible mechanism of pathogenesis as a photo essay. METHODS: Records from all patients with ERM were obtained from Osaka Medical College Hospital from January 2001 to October 2012. Visual acuity (VA), fundus photo, and optical coherence tomography (OCT) were reviewed using the medical records. For statistical analysis, VA measured with a Landolt chart was converted to the logarithm of the minimum angle of resolution (logMAR)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28967071/outcomes-of-cataract-surgery-in-children-with-persistent-hyperplastic-primary-vitreous
#15
Jitender Jinagal, Parul C Gupta, Jagat Ram, Manu Sharma, Simar R Singh, Sonam Yangzes, Jaspreet Sukhija, Ramandeep Singh
PURPOSE: To evaluate postoperative outcomes of cataract surgery in children with persistent hyperplastic primary vitreous (PHPV) and factors affecting outcomes. METHODS: We analyzed 29 eyes of 28 children with PHPV presenting at a tertiary care center in northern India. All eyes underwent phacoaspiration followed by primary posterior capsulotomy with or without cauterization of persistent fetal vasculature under general anesthesia. Hydrophobic intraocular lens was implanted in selective cases...
September 14, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28963579/pharmacokinetics-and-efficacy-of-intraocular-flurbiprofen
#16
S Blazaki, C Tsika, M Tzatzarakis, E Naoumidi, A Tsatsakis, C Tsatsanis, Miltiadis K Tsilimbaris
PURPOSE: Intravitreal delivery of non-steroidal anti-inflammatory drugs could be an effective way to treat macular edema caused by posterior segment inflammation. In this study, we evaluated the intravitreal bioavailability and anti-inflammatory efficacy of flurbiprofen in rabbit eyes. METHODS: For pharmacokinetics, 0.1 ml of 7.66 mg/ml flurbiprofen solution was injected intravitreally and vitreous drug levels were analyzed at specific time points using LC-MS technique...
September 29, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28944207/predictive-factors-of-visual-outcome-of-malaysian-cataract-patients-a-retrospective-study
#17
Thanigasalam Thevi, Myron Anthony Godinho
AIM: To explore the associations between various characteristics of Malaysian cataract patients and their management, and their post-operative visual outcomes, to inform relevant bodies to reduce cataract-related blindness. METHODS: We conducted a descriptive secondary data analysis of cataract surgery patients in Melaka Hospital, from 2007 to 2014 using the National Eye Database (NED). Patient-related factors (demographic features, systemic and ocular comorbidities) and management-related factors (surgical duration, type of surgery, type of lens) were analysed for their association with visual outcome (acuity)...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28928264/role-of-ultrasound-biomicroscopy-in-diagnosis-of-ocular-toxocariasis
#18
Qian Chen, Junxiang Gu, Rui Jiang, Min Zhou, Qing Chang
PURPOSE: To investigate ultrasound biomicroscopy (UBM) characteristics of patients with ocular toxocariasis (OT) and to explore the role of UBM in the diagnosis and differential diagnosis of OT. DESIGN: Cross-sectional study. METHODS: 78 eyes of 77 patients clinically consistent with OT and confirmed by serum and/or intraocular antibodies in a single tertiary centre (Fudan University Eye and ENT Hospital, Shanghai) between July 2009 and July 2016 were included in the study...
September 19, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28867131/posterior-vitreous-detachment-and-the-posterior-hyaloid-membrane
#19
Gregory S Fincham, Sean James, Carl Spickett, Michael Hollingshead, Christopher Thrasivoulou, Arabella V Poulson, Annie McNinch, Allan Richards, David Snead, Gloria A Limb, Martin P Snead
PURPOSE: Despite posterior vitreous detachment being a common ocular event affecting most individuals in an aging population, there is little consensus regarding its precise anatomic definition. We investigated the morphologic appearance and molecular composition of the posterior hyaloid membrane to determine whether the structure clinically observed enveloping the posterior vitreous surface after posterior vitreous detachment is a true basement membrane and to postulate its origin. Understanding the relationship between the vitreous (in both its attached and detached state) and the internal limiting membrane of the retina is essential to understanding the cause of rhegmatogenous retinal detachment and vitreoretinal interface disorders, as well as potential future prophylactic and treatment strategies...
August 31, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28859118/tumor-parameters-predict-the-risk-of-side-effects-after-ruthenium-106-plaque-brachytherapy-of-uveal-melanomas
#20
Lisa Tarmann, Werner Wackernagel, Domagoj Ivastinovic, Mona Schneider, Peter Winkler, Gerald Langmann
BACKGROUND: To report on radiation-related side effects and complications after ruthenium-106 plaque brachytherapy of uveal melanomas. METHODS: Medical records of 143 eyes with uveal melanoma, treated by ruthenium-106 brachytherapy between 1997 and 2012 at a single center, were analyzed. We evaluated the occurrence of radiation-related side effects on the anterior and posterior segment of the eye. The influence of patient, tumor and treatment parameters on outcome was analyzed by multivariate time to event analysis considering competing risks...
2017: PloS One
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