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Breath holding spells

Sheffali Gulati, Harsh Patel, Biswaroop Chakrabarty, Rachana Dubey, N K Arora, R M Pandey, V K Paul, Konanki Ramesh, Vyshakh Anand, Ankit Meena
OBJECTIVES: There is shortage of specialists for the diagnosis of children with epilepsy, especially in resource limited settings. Existing INCLEN (International Clinical Epidemiology Network) instrument was validated for children aged 2-9 years. The current study validated modifications of the same including wider symptomatology and age group. METHODS: The Modified INCLEN tool was validated by a team of experts by modifying the existing tools (2-9 years) to widen the age range from 1 month to 18 years and include broader symptomatology in a tertiary care teaching hospital of North India between January and June 2015...
February 2017: Epilepsy Research
Shai Tejman-Yarden, Bruria Ben-Zeev, Yuval Goldshmit, Georgia Sarquella-Brugada, Assi Cicurel, Uriel Katz, David Mishali, Michael Glikson
BACKGROUND: Pacing can be a successful treatment for pallid breath-holding spells, primarily in individuals with severe bradycardia. PATIENT DESCRIPTION: We describe an 18-month-old girl experiencing severe pallid breath-holding spells in whom repeated electrocardiographic, Holter, and electroencephalographic monitoring tests were all normal. RESULTS: Using a subcutaneous insertable cardiac monitor, severe bradycardia was detected during one of this girl's episodes...
November 2016: Pediatric Neurology
A V Pol'skaya, L S Chutko, E V Yakovenko
AIM: To study the efficacy of pantogam syrup 10% (hopantenic acid) in the treatment of breath-holding spells (BHS). MATERIAL AND METHODS: Sixty children, aged from 2 to 4 years, with BHS were studied. The evaluation of clinical manifestations and anxiety level was performed. Results of neurophysiological examination (long-term video-EEG-monitoring) were analyzed. Children were divided into 2 groups: main, in which the patients received pantogam syrup, and control group, in which only psychological methods were used...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
Wenhua Zhang, Cheng Wang, Runmei Zou, Liping Liu, Lijia Wu, Xuemei Luo, Fang Li, Donglei Liao, Hong Cai
OBJECTIVE: To explore the change of the amplitude of P wave, T wave and ST segment of 12 lead electrocardiogram (ECG) in children with breath holding spell.
 METHODS: A total of 29 children (24 males and 5 females) with breath holding spell in Second Xiangya Hospital, Central South University were enrolled for this study from October, 2009 to September, 2015. Their ages ranged from 3 months to 6 years, with an average of 1.82±1.27 years old. The control group consisted of 30 age-matched and gender-matched healthy children...
June 28, 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
Aleksandra Gergont
UNLABELLED: The aims of the study was to establish current knowledge regarding the involvement of autonomic nervous system (ANS) in paroxysmal disorders in children and available diagnostic tools. MATERIAL AND METHODS: Using key words ANS, epilepsy, syncope and breath-holding spells the search was performed in collections of Elsevier and Springer Journals, as well as MEDLINE/PubMed. RESULTS: Manifestation of ANS dysfunction may constitute the group of leading symptoms and signs of many diseases, including epilepsy with autonomic attacks and familial dysautonomia...
2016: Przegla̧d Lekarski
Abdelrahim Abdrabou Sadek, Montaser Mohamed Mohamed, El-Zahraa El-Said Ahmed Sharaf, Rofaida Mohamed Magdy, Ahmed Ahmed Allam
INTRODUCTION: Breath-holding spells (BHSs) are involuntary pauses of breathing, sometimes accompanied by loss of consciousness. They usually occur in response to an upsetting or surprising situation. Breath-holding spells are usually caused by either a change in the usual breathing pattern or a slowing of the heart rate. In some children, BHSs may be related to iron deficiency anemia. The aim of the work was to study the clinical and laboratory profile of BPHs in children presented to the Neuropediatric Clinic at Sohag University Hospital...
April 2016: Electronic Physician
Nurullah Bolat, Kayi Eliacik, Enis Sargin, Ali Kanik, Figen Baydan, Berrak Sarioglu
Objective Mothers of individuals with breath-holding spells (BHS) suffer more often from anxiety and experience more stressors in their everyday life. The purpose of this study was to examine the efficacy of psychoeducational intervention in reducing BHS and coping with these spells. Participants and Methods Mothers who have children with BHS were randomly assigned to one of the two groups: an intervention group receiving psychoeducational therapy in addition to the routine follow-up (n = 31) and a control group who did not receive psychoeducation in their routine follow-up (n = 28)...
August 2016: Neuropediatrics
Kayi Eliacik, Nurullah Bolat, Ali Kanik, Enis Sargin, Ellen Selkie, Nurhan Korkmaz, Figen Baydan, Ebru Akar, Berrak Sarioglu
AIM: This study aimed to identify differences in the antenatal stressful life events, parenting style, family functioning, depression and anxiety of mothers who have children with breath-holding spells (BHS) compared with controls. METHODS: This case control study divided 66 children into a group of children with BHS and a control group, with the children's ages ranging between 6 months and 5 years of age. This study explored underlying anxiety and depression in mothers as well as functioning of their families...
May 2016: Journal of Paediatrics and Child Health
Sanna Hellström Schmidt, Ulf Tedgård, Cornelis J H Pronk
AIM: This study aimed to evaluate the concomitant occurrence and possible association of breath-holding spells (BHS) and transient erythroblastopenia of childhood (TEC). METHODS: This population-based cohort study, carried out in Southern Sweden from 2004 to 2014, included patients with BHS and/or anaemia, including TEC. The subjects were evaluated for the presence of all three conditions and the diagnostic workups, disease characteristics and outcome were analysed...
September 2016: Acta Paediatrica
Amir Hosein Movahedian, Marzieh Heidarzadeh Arani, Davood Motaharizad, Gholam Abbas Mousavi, Ziba Mosayebi
OBJECTIVE: Breath holding spells (BHS) are common involuntary reflexes in infancy and early childhood. Differential diagnosis should embrace Long QT Syndrome (LQTS) and paroxysmal abnormalities of rhythm. The aim of this study was to compare QT dispersion (QTd) in children with breath holding spells and normal controls. MATERIALS & METHODS: QT dispersion and Corrected QT(QTc) dispersion were measured in 12 lead surface electrocardiograms in 56 patients with BHS and compared with healthy children of the same age referred to the clinic for regular checkup visits...
2016: Iranian Journal of Child Neurology
Preeti Singh, Anju Seth
No abstract text is available yet for this article.
August 2015: Indian Pediatrics
Aaron J Charnay, Jeanne E Antisdel-Lomaglio, Frank A Zelko, Casey M Rand, Michele Le, Samantha C Gordon, Sally F Vitez, Jennifer W Tse, Cindy D Brogadir, Michael N Nelson, Elizabeth M Berry-Kravis, Debra E Weese-Mayer
BACKGROUND: Congenital Central Hypoventilation Syndrome (CCHS) is a rare neurocristopathy characterized by severe hypoventilation and autonomic dysregulation, with typical presentation in the neonatal period, and deficient cognitive skills in school-aged patients. We hypothesized that younger (preschool) children with CCHS would also show neurocognitive delay and that CCHS-related physiologic factors would impact neurocognitive test results. METHODS: We studied developmental (Bayley) test results collected during routine clinical care in 31 children (mean age 25...
March 2016: Chest
J Naud
Most infant apparent life-threatening events (ALTEs) are minor with spontaneously favorable prognosis. Frequent etiologies are gastroesophageal reflux, obstructive apneas, respiratory infections, and breath-holding spells. Some rare but potentially serious causes must be discussed. Diagnosis is usually guided by careful questioning of the parents and repeated clinical examinations. A few complementary examinations are systematically needed and their performance is increased if they are oriented by clinical aspects...
September 2015: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Seham F A Azab, Ahmed G Siam, Safaa H Saleh, Mona M Elshafei, Wafaa F Elsaeed, Mohamed A Arafa, Eman A Bendary, Elsayed M Farag, Maha A A Basset, Sanaa M Ismail, Osama M A Elazouni
The mechanism of breath-holding spells (BHS) is not fully understood and most probably multifactorial; so, this study was designed to clarify the pathophysiology of BHS through assessing some laboratory parameters and electrocardiographic (ECG) changes which might be contributing to the occurrence of the attacks. Another aim of the study was to evaluate the differences in the pathophysiology between pallid and cyanotic types of BHS. This was a prospective study performed in Zagazig University Hospitals. Seventy-six children diagnosed with BHS were included as follows: 32 children with cyanotic BHS, 14 children with pallid BHS, and 30 healthy children as a control group...
July 2015: Medicine (Baltimore)
Bruno Kolterer, Roman Antonin Gebauer, Jan Janousek, Ingo Dähnert, Frank Thomas Riede, Christian Paech
OBJECTIVES: To validate the physical and psychological effectiveness of cardiac pacing in pediatric patients with breath-holding spells (BHS) and prolonged asystole. MATERIALS AND METHODS: The records and clinical data of all the patients with BHS who presented to our center in the period of 2001-2013 were reviewed. All patients who received cardiac pacemaker implantation for prolonged asystole during BHS were included. In addition, the parents were asked to fill out a standardized quality of life (QOL) questionnaire...
May 2015: Annals of Pediatric Cardiology
Mustafa Calik, Ahmet Ciftci, Suna Sarikaya, Ozcan Kocaturk, Mahmut Abuhandan, Abdullah Taskin, Hasan Kandemir, Tahır Kurtulus Yoldas, Nurten Aksoy
OBJECTIVE: Breath-holding spells are common paroxysmal events in children. Although the spells have a benign prognosis in the long term, they may be complicated by loss of consciousness, tonic-clonic movements, and occasionally seizures. Hence, this study aimed to measure the levels of serum S-100B proteins and neuropeptide-Y in the blood of children who experience breath-holding spells. METHODS: The study groups consisted of 45 patients (13 females, 32 males) with breath-holding spells and a control group of 32 healthy individuals (12 females, 20 males)...
June 2015: Epilepsy & Behavior: E&B
Isa Ozyilmaz, Husnu Fırat Altin, Okan Yildiz, Ersin Erek, Yakup Ergul, Alper Guzeltas
Non-syndromic congenital supravalvular aortic stenosis (SVAS) leads to ventricular hypertrophy and increased oxygen consumption, and when combined with other factors reduces coronary blood flow, potentially resulting in myocardial ischemia and sudden cardiac death. While the anatomic obstruction of coronary circulation is as common in non-syndromic SVAS as in Williams syndrome, it often remains unacknowledged. Extracorporeal membrane oxygenation (ECMO) is an elective procedure that can be used to support patients with cardiac arrest during diagnosis as a way to reduce cardiopulmonary load in preparation for surgery or further treatment...
June 2015: Pediatrics International: Official Journal of the Japan Pediatric Society
Jeffrey A Robinson, J Martijn Bos, Susan P Etheridge, Michael J Ackerman
BACKGROUND: Long QT syndrome (LQTS) is a genetic heart rhythm disorder that may present with syncope, seizures, or sudden cardiac death. Breath holding spells (BHS) occur in 5% of all children and have been noted in children with LQTS anecdotally. The purpose of this study was to determine the frequency of BHS in children diagnosed with LQTS at ≤5 years of age. DESIGN: A retrospective review was performed to identify children diagnosed with LQTS who were ≤5 years old at initial presentation to our LQTS clinic from August 1999 to November 2013...
July 2015: Congenital Heart Disease
Jason Williams, Nicole Cain
Breath-holding spells are a common childhood disorder that typically present before 12 months of age. Whereas most cases are benign, some patients have very severe cases associated with bradycardia that can progress from asystole to syncope and seizures. Treatment studies have implicated the use of several therapies, such as oral iron, fluoxetine, and pacemaker implantation. This is a retrospective study of patients treated with glycopyrrolate for pallid breath-holding spells. Clinical data from 4 patients referred to pediatric cardiology who saw therapeutic benefit from treatment using glycopyrrolate were reviewed to evaluate for clinical response to the drug...
May 2015: Pediatrics
Ran D Goldman
QUESTION: I have children in my clinic who experience seizurelike episodes in which they cry and hold their breath to the point of cyanosis and loss of consciousness. Their examination or investigation findings are normal and referral to a pediatric specialist results in no further investigation. Are breath-holding spells common, and what type of investigation is needed? ANSWER: A breath-holding spell is a benign paroxysmal nonepileptic disorder occurring in healthy children 6 to 48 months of age...
February 2015: Canadian Family Physician Médecin de Famille Canadien
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