Brian A Figueroa, Carlos X Ordenana, Majid Rezaei, Sayf A Said, Vahe Fahradyan, Edoardo Dalla Pozza, Lynn M Orfahli, Maria Madajka, Varun Kopparthy, Frank Papay, Antonio Rampazzo, Bahar Bassiri Gharb
INTRODUCTION: Above elbow transplants represent 19% of the upper extremity transplants. Previous large-animal models have been too distal or heterotopic, did not use immunosuppression and had short survival. We hypothesize that an orthotopic forelimb transplant model, under standard immunosuppression, is feasible and can be used to address questions on peri-transplant ischemia reperfusion injury, and post-transplantation vascular, immunologic, infectious, and functional outcomes. MATERIALS AND METHODS: Four forelimbs were used for anatomical studies...
February 2024: Microsurgery