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https://www.readbyqxmd.com/read/28107532/social-determinants-of-hiv-disparities-in-the-southern-united-states-and-in-counties-with-historically-black-colleges-and-universities-hbcus-2013-2014
#1
Madeline Y Sutton, Simone C Gray, Kim Elmore, Zaneta Gaul
HIV infection disproportionately affects Blacks in the southern United States (U.S.), a region where legal policies that may unintentionally impede earlier HIV detection and treatment are prevalent. Historically Black Colleges and Universities (HBCUs) have historically facilitated social change in communities of color and have been underexplored as partners for HIV prevention. We describe geographic and social determinants of health (SDH) in the southern U.S. to inform potential HBCU-public health partnerships that might improve HIV health equity...
2017: PloS One
https://www.readbyqxmd.com/read/28103120/compassionate-options-for-pediatric-ems-cope-addressing-communication-skills
#2
Aaron W Calhoun, Erica R H Sutton, Anita P Barbee, Beth McClure, Carrie Bohnert, Richard Forest, Peter Taillac, Mary E Fallat
INTRODUCTION: Each year, 16,000 children suffer cardiopulmonary arrest, and in one urban study, 2% of pediatric EMS calls were attributed to pediatric arrests. This indicates a need for enhanced educational options for prehospital providers that address how to communicate to families in these difficult situations. In response, our team developed a cellular phone digital application (app) designed to assist EMS providers in self-debriefing these events, thereby improving their communication skills...
January 19, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28102617/feasibility-of-a-psychosis-information-intervention-to-improve-mental-health-literacy-for-professional-groups-in-contact-with-young-people
#3
Marie Sutton, Donal O'Keeffe, Timothy Frawley, Kevin Madigan, Felicity Fanning, Elizabeth Lawlor, Eric Roche, Aine Kelly, Niall Turner, Arielle Horenstein, Eadbhard O'Callaghan, Mary Clarke
The aim of this study was to assess the feasibility of a psychosis information intervention for professionals in contact with young people in Ireland. A quasi-experimental pre- and post-intervention design was used. One thousand and thirty-two professionals received an information intervention designed to improve mental health literacy (MHL) and confidence in providing help to people with psychosis. Seven hundred and fifty-five participants completed the Psychosis Information and Confidence Questionnaire pre- and post-intervention...
January 19, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/28100453/mechanisms-of-vasovagal-syncope-in-the-young-reduced-systemic-vascular-resistance-versus-reduced-cardiac-output
#4
Julian M Stewart, Marvin S Medow, Richard Sutton, Paul Visintainer, David L Jardine, Wouter Wieling
BACKGROUND: Syncope is a sudden transient loss of consciousness and postural tone caused by cerebral hypoperfusion. The most common form is vasovagal syncope (VVS). Presyncopal progressive early hypotension in older VVS patients is caused by reduced cardiac output (CO); younger patients have reduced systemic vascular resistance (SVR). Using a priori criteria for reduced CO (↓CO) and SVR (↓SVR), we studied 48 recurrent young fainters comparing subgroups of VVS with VVS-↓CO, VVS-↓SVR, and both VVS-↓CO&↓SVR...
January 18, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28097233/ectonucleotidase-cd39-driven-control-of-postinfarction-myocardial-repair-and-rupture
#5
Nadia R Sutton, Takanori Hayasaki, Matthew C Hyman, Anuli C Anyanwu, Hui Liao, Danica Petrovic-Djergovic, Linda Badri, Amy E Baek, Natalie Walker, Keigo Fukase, Yogendra Kanthi, Scott H Visovatti, Ellen L Horste, Jessica J Ray, Sascha N Goonewardena, David J Pinsky
Mechanical complications of myocardial infarction (MI) are often fatal. Little is known about endogenous factors that predispose to myocardial rupture after MI. Ectonucleoside triphosphate diphosphohydrolase (CD39) could be a critical mediator of propensity to myocardial rupture after MI due to its role in modulating inflammation and thrombosis. Using a model of permanent coronary artery ligation, rupture was virtually abrogated in cd39(-/-) mice versus cd39(+/+) controls, with elevated fibrin and collagen deposition and marked neutrophil and macrophage influx...
January 12, 2017: JCI Insight
https://www.readbyqxmd.com/read/28094637/praying-for-patients
#6
Julie Sutton, Nicola Macey
I feel sad for the nurse who was sacked for praying for a patient. Whatever happened to freedom of speech? What is wrong with offering to pray with patients? I pray this nurse finds a job where people appreciate her.
January 4, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28094180/antifungal-activity-of-substituted-aurones
#7
Caleb L Sutton, Zachary E Taylor, Mary B Farone, Scott T Handy
Novel antifungals are in high demand as there is a growing resistance to antifungals currently in use. In particular, opportunistic fungal infections caused by Candida spp. are on the rise with infections by this genus accounting for the most severe fungal infections following chemotherapy, implantation procedures, and in patients with HIV/AIDS. A series of simple aurone analogs were synthesized and screened for antifungal activity versus Candida spp. Several compounds displayed activity at 100μM, with two having IC50 values below 20μM for three species of Candida...
January 6, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28078658/the-past-does-matter-a-nursing-perspective-on-post-traumatic-slave-syndrome-ptss
#8
Ejim Sule, Ryan M Sutton, Debbie Jones, Ramel Moore, Imaculata Igbo, Lovell A Jones
Few have reviewed the impact of post traumatic slave syndrome (PTSS) on the issues of inequities, especially as it pertains to mental and physical health. Furthermore, the impact of PTSS on the social determinants of health is an area that has been researched by few investigators. The possibilities that the impact of slavery and/or major stress events in the life of a population can become trans-generational are lost to history. Think about what is taking place in cities around the country and then think about racist socialization (internalized racism) and its impact on our society...
January 11, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28078131/a-novel-management-of-post-oesophagectomy-gastro-pleural-fistula
#9
Javaid Ishtiaq, Jonathan Sutton, Waqar Ahmed
Oesophageal anastomotic leak and fistula are major and life-threatening complications of oesophagectomy with resultant increased mortality. Non-operative approach of such cases should be the initial strategy. Re-operative surgery and/or stent insertion are considered if conservative measures failed. Although oesophageal stenting is a safe option for the leaks, stent migration and failure to completely cover large anastomotic leaks are the main complications and pitfalls of the procedure. These can be overcome by using multiple or larger stents...
December 2016: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28074845/local-coexistence-and-genetic-isolation-of-three-pollinator-species-on-the-same-fig-tree-species
#10
T L Sutton, J L DeGabriel, M Riegler, J M Cook
Molecular tools increasingly reveal cryptic lineages and species that were previously unnoticed by traditional taxonomy. The discovery of cryptic species in sympatry prompts the question of how they coexist in the apparent absence of ecological divergence. However, this assumes first that the molecular taxonomy used to identify cryptic lineages delimits species boundaries accurately. This issue is important, because many diversity studies rely heavily or solely on data from mitochondrial DNA sequences for species delimitation, and several factors may lead to poor identification of species boundaries...
January 11, 2017: Heredity
https://www.readbyqxmd.com/read/28074683/objectively-measured-sedentary-behavior-and-brain-volumetric-measurements-in-multiple-sclerosis
#11
Rachel E Klaren, Elizabeth A Hubbard, Nathan C Wetter, Bradley P Sutton, Robert W Motl
AIM: This study examined the association between sedentary behavior patterns and whole brain gray matter (GM), white matter (WM) and subcortical GM structures in persons with multiple sclerosis (MS). METHODS: 36 persons with MS wore an accelerometer and underwent a brain MRI. Whole brain GM and WM and deep GM structures were calculated from 3D T1-weighted structural brain images. RESULTS: There were statistically significant (p < 0.01) and moderate or large associations between number of sedentary bouts/day and brain volume measures...
January 11, 2017: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/28071300/-going-episodic-collaborative-inhibition-and-facilitation-when-long-married-couples-remember-together
#12
Celia B Harris, Amanda J Barnier, John Sutton, Paul G Keil, Roger A Dixon
Two complementary approaches to the study of collaborative remembering have produced contrasting results. In the experimental "collaborative recall" approach within cognitive psychology, collaborative remembering typically results in "collaborative inhibition": laboratory groups recall fewer items than their estimated potential. In the cognitive ageing approach, collaborative remembering with a partner or spouse may provide cueing and support to benefit older adults' performance on everyday memory tasks. To combine the value of experimental and cognitive ageing approaches, we tested the effects of collaborative remembering in older, long-married couples who recalled a non-personal word list and a personal semantic list of shared trips...
January 10, 2017: Memory
https://www.readbyqxmd.com/read/28066519/economic-evaluations-of-interventions-for-transtibial-amputees-a-scoping-review-of-comparative-studies
#13
M Jason Highsmith, Jason T Kahle, Amanda Lewandowski, Tyler D Klenow, John J Orriola, Rebecca M Miro, Owen T Hill, Sylvia Ursula Raschke, Michael S Orendurff, James T Highsmith, Bryce S Sutton
Transtibial amputation (TTA) is life-altering emotionally, functionally, and economically. The economic impact to all stakeholders is largely unknown, as is the cost-effectiveness of prosthetic intervention. This scoping report's purpose was to determine if there is sufficient evidence to conduct a formal systematic review or meta-analysis in any particular prosthetic intervention area and to determine if any evidence statements could be synthesized relative to economic evaluation of interventions provided to patients with TTA...
September 2016: Technology and Innovation
https://www.readbyqxmd.com/read/28061884/treeman-an-r-package-for-efficient-and-intuitive-manipulation-of-phylogenetic-trees
#14
Dominic J Bennett, Mark D Sutton, Samuel T Turvey
BACKGROUND: Phylogenetic trees are hierarchical structures used for representing the inter-relationships between biological entities. They are the most common tool for representing evolution and are essential to a range of fields across the life sciences. The manipulation of phylogenetic trees-in terms of adding or removing tips-is often performed by researchers not just for reasons of management but also for performing simulations in order to understand the processes of evolution. Despite this, the most common programming language among biologists, R, has few class structures well suited to these tasks...
January 7, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28059962/intraoperative-micro-breaks-with-targeted-stretching-enhance-surgeon-physical-function-and-mental-focus-a-multicenter-cohort-study
#15
Adrian E Park, Hamid R Zahiri, M Susan Hallbeck, Vedra Augenstein, Erica Sutton, Denny Yu, Bethany R Lowndes, Juliane Bingener
OBJECTIVE: The aim of this study was to investigate the effect of intraoperative targeted stretching micro breaks (TSMBs) on the experienced pain and fatigue, physical functions, and mental focus of surgeons. BACKGROUND: Surgeons are routinely subject to mental and physical stresses through the course of their work in the operating room. One of the factors most contributory to the shortening of a surgeon's career is work-related pain and its effects on patient safety and personal relationships...
February 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28053212/multilocus-phylogeny-and-antifungal-susceptibility-of-aspergillus-section-circumdati-from-clinical-samples-and-description-of-a-pseudosclerotiorum-sp-nov
#16
J P Z Siqueira, D A Sutton, J Gené, D García, N Wiederhold, S W Peterson, J Guarro
A multilocus phylogenetic study was carried out to assess species identity of a set of 34 clinical isolates from Aspergillus section Circumdati from the USA, and to determine their in vitro antifungal susceptibility against eight antifungal drugs. The genetic markers used were ITS, BenA, CaM and RPB2, and the drugs tested were amphotericin B, itraconazole, posaconazole, voriconazole, anidulafungin, caspofungin, micafungin, and terbinafine. The most common species sampled was A. westerdijkiae (29.4%), followed by a novel species, which was described here as A...
January 4, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28052137/mapping-polyclonal-hiv-1-antibody-responses-via-next-generation-neutralization-fingerprinting
#17
Nicole A Doria-Rose, Han R Altae-Tran, Ryan S Roark, Stephen D Schmidt, Matthew S Sutton, Mark K Louder, Gwo-Yu Chuang, Robert T Bailer, Valerie Cortez, Rui Kong, Krisha McKee, Sijy O'Dell, Felicia Wang, Salim S Abdool Karim, James M Binley, Mark Connors, Barton F Haynes, Malcolm A Martin, David C Montefiori, Lynn Morris, Julie Overbaugh, Peter D Kwong, John R Mascola, Ivelin S Georgiev
Computational neutralization fingerprinting, NFP, is an efficient and accurate method for predicting the epitope specificities of polyclonal antibody responses to HIV-1 infection. Here, we present next-generation NFP algorithms that substantially improve prediction accuracy for individual donors and enable serologic analysis for entire cohorts. Specifically, we developed algorithms for: (a) selection of optimized virus neutralization panels for NFP analysis, (b) estimation of NFP prediction confidence for each serum sample, and (c) identification of sera with potentially novel epitope specificities...
January 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28046969/su-d-207b-04-morphological-features-of-mri-as-a-correlate-of-capsular-contracture-in-breast-cancer-patients-with-implant-based-reconstructions
#18
N Tyagi, E Sutton, M Hunt, A Apte, J Zhang, J Oh, J Mechalakos, B Mehrara, E Matros, A Ho
PURPOSE: Capsular contracture (CC) is a serious complication in patients receiving implant-based reconstruction for breast cancer. The goal of this study was to identify image-based correlates of CC using MRI imaging in breast cancer patients who received both MRI and clinical evaluation following reconstructive surgery. METHODS: We analyzed a retrospective dataset of 50 patients who had both a diagnostic MR and a plastic surgeon's evaluations of CC score (Baker's score) within a six month period following mastectomy and reconstructive surgery...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045714/how-much-should-we-pay-to-minimize-pancreatic-leak-the-cost-effectiveness-of-pasireotide-in-pancreatic-resection-retracted
#19
Daniel E Abbott, Jeffrey M Sutton, Peter L Jernigan, Alex Chang, Patrick Frye, Shimul A Shah, Daniel P Schauer, Mark H Eckman, Syed A Ahmad, Jeffrey J Sussman
INTRODUCTION: Pasireotide was recently shown to decrease leak rates after pancreatic resection, though the significant cost of the drug may be prohibitive. We conducted a cost-effectiveness analysis to determine whether prophylactic pasireotide possesses a reasonable cost profile by improving outcomes. METHODS: A cost-effectiveness model was constructed to compare pasireotide administration after pancreatic resection versus usual care, populated by probabilities of clinical outcomes from a recent randomized trial and hospital costs (2013 US$) from a university pancreatic disease center...
December 30, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/28045573/disparities-in-retention-in-hiv-care-among-hiv-infected-young-men-who-have-sex-with-men-in-the-district-of-columbia-2013
#20
Mercedes M Morales-Alemán, Jenevieve Opoku, Ashley Murray, Yzette Lanier, Michael Kharfen, Madeline Y Sutton
PURPOSE: Among young men who have sex with men (YMSM), aged 13-24 years, blacks/African Americans and Hispanics/Latinos are disproportionately affected by HIV, accounting for 58% and 21%, respectively, of diagnoses of HIV infection in the United States. In the District of Columbia (DC), YMSM of color are also disproportionately affected by HIV. National goals are that 80% of HIV-infected persons be retained in HIV care. We analyzed DC surveillance data to examine retention among YMSM living with HIV infection in DC...
January 3, 2017: LGBT Health
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