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Early Warning System

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https://www.readbyqxmd.com/read/28101490/periodic-granulocyte-count-measuring-is-useful-for-detecting-asymptomatic-agranulocytosis-in-antithyroid-drug-treated-patients-with-graves-disease
#1
Hirotoshi Nakamura, Akane Ide, Takumi Kudo, Eijun Nishihara, Mitsuru Ito, Akira Miyauchi
OBJECTIVE: Finding agranulocytosis (AG) at an early stage is important to improve outcome, but periodic granulocyte count monitoring is not generally recommended for patients with Graves' disease, because AG develops suddenly. METHOD: At the Kuma Hospital, Graves' patients under antithyroid drug (ATD) treatment in an outpatient clinic have a granulocyte count examination during each visit, and if it is <1,000/μl, a warning is immediately sent to the patient's physician...
December 2016: European Thyroid Journal
https://www.readbyqxmd.com/read/28100027/moving-beyond-presence-and-absence-when-examining-changes-in-species-distributions
#2
Michael B Ashcroft, Diana H King, Ben Raymond, Johanna D Turnbull, Jane Wasley, Sharon A Robinson
Species distributions are often simplified to binary representations of the ranges where they are present and absent. It is then common to look for changes in these ranges as indicators of the effects of climate change, the expansion or control of invasive species or the impact of human land use changes. We argue that there are inherent problems with this approach, and more emphasis should be placed on species relative abundance rather than just presence. The sampling effort required to be confident of absence is often impractical to achieve, and estimates of species range changes based on survey data are therefore inherently sensitive to sampling intensity...
January 18, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28099733/implementation-of-a-modified-obstetric-early-warning-system-to-improve-the-quality-of-obstetric-care-in-zimbabwe
#3
Abi Merriel, Bobb T Murove, Samuel W D Merriel, Thabani Sibanda, Sikangezile Moyo, Joanna Crofts
OBJECTIVE: To implement a modified obstetric early warning system (MOEWS) to promote identification and stabilization of unwell women. METHODS: A before-and-after study of MOEWS implementation took place between April 2013 and January 2014 in a government referral hospital in Bulawayo, Zimbabwe. After piloting MOEWS, cesarean case files were retrospectively assessed to compare preoperative stabilization. A longitudinal "spot-check" study measured use of MOEWS and action taken on abnormal results...
February 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28088544/off-site-impacts-of-wildfires-on-aquatic-systems-biomarker-responses-of-the-mosquitofish-gambusia-holbrooki
#4
Bruno Nunes, Vera Silva, Isabel Campos, Joana Luísa Pereira, Patrícia Pereira, Jan Jacob Keizer, Fernando Gonçalves, Nelson Abrantes
The number of wildfires has markedly increased in Mediterranean Europe, including in Portugal. Wildfires are environmentally concerning, not only due to the loss of biodiversity and forest area, but also as a consequence of environmental contamination by specific compounds including metals and polycyclic aromatic compounds (PAHs). These contaminants, mostly bound to ashes, can reach downstream water bodies, namely through surface runoff, being ultimately dispersed by vast areas and contacting with aquatic biota...
January 11, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28087145/-computerised-sepsis-protocol-management-description-of-an-early-warning-system
#5
Begoña de Dios, Marcio Borges, Timothy D Smith, Alberto Del Castillo, Antonia Socias, Leticia Gutiérrez, Jordi Nicolás, Bartolomé Lladó, Jose A Roche, Maria P Díaz, Yolanda Lladó
INTRODUCTION: New strategies need to be developed for the early recognition and rapid response for the management of sepsis. To achieve this purpose, the Multidisciplinary Sepsis Team (MST) developed the Computerised Sepsis Protocol Management (PIMIS). The aim of this study was to evaluate the convenience of using PIMIS, as well as the activity of the MST. METHODS: An analysis was performed on the data collected from solicited MST consultations (direct activation of PIMIS by attending physician or telephone request) and unsolicited ones (by referral from the microbiology laboratory or an automatic referral via the hospital vital signs recording software [SIDCV]), as well as the hospital department, source of infection, treatment recommendation, and acceptance of this...
January 10, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/28075420/the-trend-of-voluntary-warnings-in-electronic-nicotine-delivery-system-magazine-advertisements
#6
Ce Shang, Frank J Chaloupka
Some manufacturers of electronic nicotine delivery systems (ENDS) voluntarily carried health warnings in their advertisements. This study examined these voluntary warnings in magazine ads and plotted their trends between 2012 and early 2015. ENDS magazine ads were obtained through Kantar media and warnings were collected from the Chicago Public Library or the Trinkets and Trash surveillance system. The prevalence of voluntary warnings, warnings with the specific capitalized word "WARNING", and MarkTen warnings were examined after being weighted using factors related to exposure between January 2012 and March 2015...
January 10, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28073524/distribution-occurrence-and-biotoxin-composition-of-the-main-shellfish-toxin-producing-microalgae-within-european-waters-a-comparison-of-methods-of-analysis
#7
Sara E McNamee, Linda K Medlin, Jessica Kegel, Gary R McCoy, Robin Raine, Lucia Barra, Maria Valeria Ruggiero, Wiebe H C F Kooistra, Marina Montresor, Johannes Hagstrom, Eva Perez Blanco, Edna Graneli, Francisco Rodríguez, Laura Escalera, Beatriz Reguera, Simon Dittami, Bente Edvardsen, Joe Taylor, Jane M Lewis, Yolanda Pazos, Christopher T Elliott, Katrina Campbell
Harmful algal blooms (HABs) are a natural global phenomena emerging in severity and extent. Incidents have many economic, ecological and human health impacts. Monitoring and providing early warning of toxic HABs are critical for protecting public health. Current monitoring programmes include measuring the number of toxic phytoplankton cells in the water and biotoxin levels in shellfish tissue. As these efforts are demanding and labour intensive, methods which improve the efficiency are essential. This study compares the utilisation of a multitoxin surface plasmon resonance (multitoxin SPR) biosensor with enzyme-linked immunosorbent assay (ELISA) and analytical methods such as high performance liquid chromatography with fluorescence detection (HPLC-FLD) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) for toxic HAB monitoring efforts in Europe...
May 2016: Harmful Algae
https://www.readbyqxmd.com/read/28073444/modelling-the-hydrodynamic-conditions-associated-with-dinophysis-blooms-in-galicia-nw-spain
#8
Manuel Ruiz-Villarreal, Luz M García-García, Marcos Cobas, Patricio A Díaz, Beatriz Reguera
The northwestern Iberian coast (Galician Rías and shelf) is frequently affected by toxic harmful algal blooms (HABs) (mainly Dinophysis spp.), leading to lengthy harvesting closures in a region where aquaculture has a strong socioeconomic impact. The project ASIMUTH (http://www.asimuth.eu) aimed to develop forecasting capabilities to warn of impending HABs along the European Atlantic coast. Simulations with the ROMS model (hydrodynamical and ecological simulations complemented with Lagrangian particle tracking simulations) of the Galician coastal circulation have been performed in the framework of the ASIMUTH project to characterize and forecast oceanographic conditions before and during HAB periods...
March 2016: Harmful Algae
https://www.readbyqxmd.com/read/28073443/a-hab-warning-system-for-shellfish-harvesting-in-portugal
#9
A Silva, L Pinto, S M Rodrigues, H de Pablo, M Santos, T Moita, M Mateus
The development of sustainable shellfish aquaculture is highly dependent on the provision of reliable monitoring and predictive information on the occurrence of harmful algal blooms (HABs). The Portuguese HAB early warning system and shellfish closures presented here is a prototype, developed in the ASIMUTH project. It relies on weekly monitoring data composed of observations of HAB species and toxin concentrations within shellfish, and ocean circulation forecasts generated by an operational oceanographic model...
March 2016: Harmful Algae
https://www.readbyqxmd.com/read/28073441/applied-simulations-and-integrated-modelling-for-the-understanding-of-toxic-and-harmful-algal-blooms-asimuth-integrated-hab-forecast-systems-for-europe-s-atlantic-arc
#10
Julie Maguire, Caroline Cusack, Manuel Ruiz-Villarreal, Joe Silke, Deirdre McElligott, Keith Davidson
Reasons for the emergent interest in HABs are abundant, including concerns associated with human health, adverse effects on biological resources, economic losses attributed to recreation, tourism and seafood related industries, and the cost of maintaining public advisory services and monitoring programs for shellfish toxins and water quality. The impact of HABs can potentially be mitigated by early warning of their development. In this regard the project ASIMUTH (Applied Simulations and Integrated Modelling for the Understanding of Toxic and Harmful algal blooms) was borne in order to develop short term HAB alert systems for Atlantic Europe...
March 2016: Harmful Algae
https://www.readbyqxmd.com/read/28073437/a-high-resolution-hydrodynamic-model-system-suitable-for-novel-harmful-algal-bloom-modelling-in-areas-of-complex-coastline-and-topography
#11
Dmitry Aleynik, Andrew C Dale, Marie Porter, Keith Davidson
Fjordic coastlines provide sheltered locations for finfish and shellfish aquaculture, and are often subject to harmful algal blooms (HABs) some of which develop offshore and are then advected to impact nearshore aquaculture. Numerical models are a potentially important tool for providing early warning of such HAB events. However, the complex topography of fjordic shelf regions is a significant challenge to modelling. This is frequently compounded by complex bathymetry and local weather patterns. Existing structured grid models do not provide the resolution needed to represent these coastlines in their wider shelf context...
March 2016: Harmful Algae
https://www.readbyqxmd.com/read/28073436/forecasting-the-risk-of-harmful-algal-blooms
#12
EDITORIAL
Keith Davidson, Donald M Anderson, Marcos Mateus, Beatriz Reguera, Joe Silke, Marc Sourisseau, Julie Maguire
The "Applied Simulations and Integrated Modelling for the Understanding of Harmful Algal Blooms" (Asimuth) project sought to develop a harmful algal bloom (HAB) alert system for Atlantic Europe. This was approached by combining, at a national or regional level, regulatory monitoring phytoplankton and biotoxin data with satellite remote sensing and other information on current marine conditions, coupled with regional scale models that included a representation of HAB transport. Synthesis of these products was achieved by expert interpretation within HAB risk alert bulletins that were prepared on a regular basis (typically weekly) for use by the aquaculture industry...
March 2016: Harmful Algae
https://www.readbyqxmd.com/read/28068732/-concept-for-a-national-implant-registry-to-improve-patient-safety
#13
L Prantl, U von Fritschen, J Liebau, J von Hassel, E M Baur, P M Vogt, R E Giunta, R E Horch
Since the introduction of silicone implants, several events have led to considerable uncertainty among the patients, public, and users. So far, however, the necessary steps to significantly improving patient safety have not been taken in any of these cases. Requiring stricter approvals for medical devices, improving monitoring by the regulatory authorities and the revision of the Medical Devices Directive are all initial steps in the right direction towards a change in policy, but are insufficient as an early warning system...
December 2016: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28064390/beap-profiles-as-rapid-test-system-for-status-analysis-and-early-detection-of-process-incidents-in-biogas-plants
#14
Sarah Refai, Stefanie Berger, Kati Wassmann, Melanie Hecht, Thomas Dickhaus, Uwe Deppenmeier
A method was developed to quantify the performance of microorganisms involved in different digestion levels in biogas plants. The test system was based on the addition of butyrate (BCON), ethanol (ECON), acetate (ACON) or propionate (PCON) to biogas sludge samples and the subsequent analysis of CH4 formation in comparison to control samples. The combination of the four values was referred to as BEAP profile. Determination of BEAP profiles enabled rapid testing of a biogas plant's metabolic state within 24 h and an accurate mapping of all degradation levels in a lab-scale experimental setup...
January 7, 2017: Journal of Industrial Microbiology & Biotechnology
https://www.readbyqxmd.com/read/28060532/critical-slowing-down-as-an-early-warning-of-transitions-in-episodes-of-bipolar-disorder-a-simulation-study-based-on-a-computational-model-of-circadian-activity-rhythms
#15
Atiyeh Bayani, Fatemeh Hadaeghi, Sajad Jafari, Greg Murray
Bipolar disorder is characterized by repeated episodes of mania and depression, and can be understood as pathological complex system behaviour involving cognitive, affective and psychomotor disturbance. Accurate prediction of episode transitions in the long-term pattern of mood changes in bipolar disorder could improve the management of the disorder by providing an objective early warning of relapse. In particular, circadian activity changes measured via actigraphy may contain clinically relevant signals of imminent systemic dysregulation...
January 6, 2017: Chronobiology International
https://www.readbyqxmd.com/read/28057139/-influence-of-data-quality-on-early-warning-sensitivity-of-syndromic-surveillance-system-based-on-medical-institutions
#16
S L Yang, M Yu, Y Z Fan, J Huang, S F Nie, S Wei
Objective: To evaluate the influence of data quality on the sensitivity of early warning syndromic surveillance system based on medical institutions in Qianjiang, Hubei province and explore the relationship between data quality and sensitivity of early warning of the system. Methods: The delay reporting rate and underreporting rate were calculated for the evaluation of the data quality. Data obtained from semi-synthetic simulated outbreak and area under the curve (AUC) were used in combination to test the sensitivity of early warning of various models and select the optimal model...
November 10, 2016: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28053366/acute-flaccid-paralysis-incidence-and-zika-virus-surveillance-pacific-islands
#17
Adam T Craig, Michelle T Butler, Roberta Pastore, Beverley J Paterson, David N Durrheim
PROBLEM: The emergence of Zika virus has challenged outbreak surveillance systems in many at-risk, low-resource countries. As the virus has been linked with Guillain-Barré syndrome, routine data on the incidence of acute flaccid paralysis (AFP) may provide a useful early warning system for the emergence of Zika virus. APPROACH: We documented all Zika virus outbreaks and cases in 21 Pacific Islands and territories for the years 2007 to 2015. We extracted data from the Global Polio Eradication Initiative database on the reported and expected annual incidence of AFP in children younger than 15 years...
January 1, 2017: Bulletin of the World Health Organization
https://www.readbyqxmd.com/read/28048269/su-f-r-12-prediction-of-truebeam-hardware-issues-using-trajectory-log-analysis
#18
D DiCostanzo, A Ayan, J Woollard, N Gupta
PURPOSE: To predict potential failures of hardware within the Varian TrueBeam linear accelerator in order to proactively replace parts and decrease machine downtime. METHODS: Machine downtime is a problem for all radiation oncology departments and vendors. Most often it is the result of unexpected equipment failure, and increased due to lack of in-house clinical engineering support. Preventative maintenance attempts to assuage downtime, but often is ineffective at preemptively preventing many failure modes such as MLC motor failures, the need to tighten a gantry chain, or the replacement of a jaw motor, among other things...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28038839/compact-radioactive-aerosol-monitoring-device-for-early-warning-networks
#19
Denis Glavič-Cindro, Drago Brodnik, Toni Petrovič, Matjaž Vencelj, Dušan Ponikvar, Steven James Bell, Lynsey Keightley, Selina Woods
In the frame of the European metrological research project MetroERM, a compact portable aerosol sampling and measurement device was developed at Jožef Stefan Institute. The system incorporates a CeBr3 scintillation detector positioned centrally within a concertinaed filter assembly and an improved high flow rate air pump. It provides continuous on-line low level airborne radioactive particulate monitoring for field station use via 3G network communications. The calibration of the device was performed at National Physical Laboratory (NPL) with filters, spiked with a certified mixed nuclide solution...
December 24, 2016: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28036003/dep-on-go-for-simultaneous-sensing-of-multiple-heavy-metals-pollutants-in-environmental-samples
#20
Madhu Biyani, Radhika Biyani, Tomoko Tsuchihashi, Yuzuru Takamura, Hiromi Ushijima, Eiichi Tamiya, Manish Biyani
We describe a simple and affordable "Disposable electrode printed (DEP)-On-Go" sensing platform for the rapid on-site monitoring of trace heavy metal pollutants in environmental samples for early warning by developing a mobile electrochemical device composed of palm-sized potentiostat and disposable unmodified screen-printed electrode chips. We present the analytical performance of our device for the sensitive detection of major heavy metal ions, namely, mercury, cadmium, lead, arsenic, zinc, and copper with detection limits of 1...
December 27, 2016: Sensors
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