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Modified Early Warning System

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https://www.readbyqxmd.com/read/29303555/an-optical-biosensor-based-quantification-of-microcystin-synthetase-a-gene-early-warning-of-toxic-cyanobacterial-blooming
#1
Jinchuan Liu, Xiaohong Zhou, Hanchang Shi
Monitoring and controlling of toxic cyanobacterial strains, which can produce microcystins, is critical to protect human and ecological health. We herein reported an optical biosensor-based quantification of microcystin synthetase A (mcyA) gene so as to discriminate microcystins-producing from non-producing strains. In this assay, the mcyA-specific ssDNA probes were designed in silico with an online tool and then synthesized to be covalently immobilized on an optical fiber surface. Production of fluorescently modified target DNA fragment amplicons was accomplished through the use of Cy5-tagged deoxycytidine triphosphates (dCTPs) in the polymerase chain reaction (PCR) method, which resulted in copies with internally labelled multiple sites per DNA molecule and delivered the great sensitivity...
January 5, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29277622/national-early-warning-score-accurately-discriminates-the-risk-of-serious-adverse-events-in-patients-with-liver-disease
#2
Theresa J Hydes, Paul Meredith, Paul E Schmidt, Gary B Smith, David R Prytherch, Richard J Aspinall
BACKGROUND & AIMS: The National Early Warning Score (NEWS) is used to identify deteriorating adult hospital inpatients. However, it includes physiological parameters frequently altered in patients with cirrhosis. We aimed to assess the performance of the NEWS in acute and chronic liver diseases. METHODS: We collected vital signs, recorded in real time, from completed consecutive admissions of patients 16 years or older to a large acute-care hospital in Southern England, from January 1, 2010 through October 31, 2014...
December 22, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29242109/short-national-early-warning-score-developing-a-modified-early-warning-score
#3
Leandro Luís, Carla Nunes
INTRODUCTION: Early Warning Score (EWS) systems have been developed for detecting hospital patients clinical deterioration. Many studies show that a National Early Warning Score (NEWS) performs well in discriminating survival from death in acute medical and surgical hospital wards. NEWS is validated for Portugal and is available for use. A simpler EWS system may help to reduce the risk of error, as well as increase clinician compliance with the tool. OBJECTIVES: The aim of the study was to evaluate whether a simplified NEWS model will improve use and data collection...
December 11, 2017: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/29181999/the-effect-of-non-steroidal-anti-inflammatory-drugs-on-severity-of-acute-pancreatitis-and-pancreatic-necrosis
#4
K A Baxter, P H Pucher, D P Berry, H Elberm, M Abu-Hilal, G Marangoni, Zzr Hamady
Introduction Acute pancreatitis (AP) is a common emergency presentation and can be disabling. There is significant morbidity and mortality associated with AP, and it places a considerable burden on the healthcare system. Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to have a protective effect in some elective contexts. This retrospective study aimed to evaluate the effect of NSAIDs on the course of AP and the severity of the disease. Methods A retrospective analysis was carried out of 324 patients admitted as an emergency with a diagnosis of AP to two UK hospitals...
November 28, 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29108458/a-fuzzy-logic-based-warning-system-for-patients-classification
#5
Jumanah A Al-Dmour, Assim Sagahyroon, A R Al-Ali, Salah Abusnana
Typically acute deterioration in sick people is preceded by subtle changes in the physiological parameters such as pulse and blood pressure. The Modified Early Warning Score is a scoring system developed to assist hospital staff in gauging these physiological changes and identifying patients in need of urgent medical care to avoid catastrophic deterioration. This work discusses the design and implementation of an equivalent warning system that utilizes fuzzy logic techniques to categorize patients' status. The system is implemented and tested in Rashid Centre for Diabetes and Research in UAE...
November 1, 2017: Health Informatics Journal
https://www.readbyqxmd.com/read/29091954/comparison-of-the-mortality-in-emergency-department-sepsis-score-modified-early-warning-score-rapid-emergency-medicine-score-and-rapid-acute-physiology-score-for-predicting-the-outcomes-of-adult-splenic-abscess-patients-in-the-emergency-department
#6
Shang-Kai Hung, Chip-Jin Ng, Chang-Fu Kuo, Zhong Ning Leonard Goh, Lu-Hsiang Huang, Chih-Huang Li, Yi-Ling Chan, Yi-Ming Weng, Joanna Chen-Yeen Seak, Chen-Ken Seak, Chen-June Seak
BACKGROUND: Splenic abscess is rare but has mortality rates as high as 14% even with recent improvements in management. Early and appropriate intervention may improve patient outcomes, yet at present there is no identified method that can predict mortality risk rapidly and accurately for emergency physicians, surgeons, and intensivists to decide on the ideal course of action. OBJECTIVE: This study aims to evaluate the performance of Mortality in Emergency Department Sepsis Score (MEDS), Modified Early Warning Score (MEWS), Rapid Emergency Medicine Score (REMS) and Rapid Acute Physiology Score (RAPS) for predicting the mortality risk of adult splenic abscess patients...
2017: PloS One
https://www.readbyqxmd.com/read/29056391/prehospital-triage-of-septic-patients-at-the-samu-regulation-comparison-of-qsofa-mrst-mews-and-presep-scores
#7
R Jouffroy, A Saade, S Ellouze, A Carpentier, M Michaloux, P Carli, B Vivien
PURPOSE: A couple of scoring systems have been developed for risk stratification of septic patients. Their performance in the management of out-of-hospital initial care delivery is not documented. This study try to evaluate the predictive ability of Quick Sequential Organ Failure Assessment (qSOFA), Robson Screening Tool (RST), Modified Early Warning Score (MEWS) and Prehospital Early Sepsis Detection (PRESEP) scores on out of-hospital triage of septic patients, to predict intensive care unit (ICU) admission...
October 12, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28918932/building-and-verifying-a-severity-prediction-model-of-acute-pancreatitis-ap-based-on-bisap-mews-and-routine-test-indexes
#8
Jiang-Feng Ye, Yu-Xin Zhao, Jian Ju, Wei Wang
PURPOSE: To discuss the value of the Bedside Index for Severity in Acute Pancreatitis (BISAP), Modified Early Warning Score (MEWS), serum Ca2+, similarly hereinafter, and red cell distribution width (RDW) for predicting the severity grade of acute pancreatitis and to develop and verify a more accurate scoring system to predict the severity of AP. METHODS: In 302 patients with AP, we calculated BISAP and MEWS scores and conducted regression analyses on the relationships of BISAP scoring, RDW, MEWS, and serum Ca2+ with the severity of AP using single-factor logistics...
October 2017: Clinics and Research in Hepatology and Gastroenterology
https://www.readbyqxmd.com/read/28915258/rapid-emergency-medicine-score-a-novel-prognostic-tool-for-predicting-the-outcomes-of-adult-patients-with-hepatic-portal-venous-gas-in-the-emergency-department
#9
MULTICENTER STUDY
Chen-June Seak, David Hung-Tsang Yen, Chip-Jin Ng, Yon-Cheong Wong, Kuang-Hung Hsu, Joanna Chen-Yeen Seak, Hsien-Yi Chen, Chen-Ken Seak
OBJECTIVE: This study aims to evaluate the performance of Rapid Emergency Medicine Score (REMS), Rapid Acute Physiology Score (RAPS), and Modified Early Warning Score (MEWS) in ascertaining the severity of illness and predicting the mortality of adult hepatic portal venous gas (HPVG) patients presenting to the emergency department (ED). This will assist emergency physicians (EPs) in risk stratification. METHODS: Data for 66 adult HPVG patients who visited the EDs of 2 research hospitals between October 1999 and April 2016 were analyzed...
2017: PloS One
https://www.readbyqxmd.com/read/28865442/midwives-experiences-of-performing-maternal-observations-and-escalating-concerns-a-focus-group-study
#10
Justine Jeffery, Alistair Hewison, Laura Goodwin, Sara Kenyon
BACKGROUND: For the past decade, Maternal Mortality Reports, published in the United Kingdom every three years, have consistently raised concerns about maternal observations in maternity care. The reports identify that observations are not being done, not being completed fully, are not recorded on Early Warning Score systems, and/or are not escalated appropriately. This has resulted in delays in referral, intervention and increases the risk of maternal morbidity or mortality. However there has been little exploration of the possible reasons for non-completion of maternal observations...
September 2, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28737573/investigating-the-impact-of-different-suspicion-of-infection-criteria-on-the-accuracy-of-quick-sepsis-related-organ-failure-assessment-systemic-inflammatory-response-syndrome-and-early-warning-scores
#11
Matthew M Churpek, Ashley Snyder, Sarah Sokol, Natasha N Pettit, Dana P Edelson
OBJECTIVE: Studies in sepsis are limited by heterogeneity regarding what constitutes suspicion of infection. We sought to compare potential suspicion criteria using antibiotic and culture order combinations in terms of patient characteristics and outcomes. We further sought to determine the impact of differing criteria on the accuracy of sepsis screening tools and early warning scores. DESIGN: Observational cohort study. SETTING: Academic center from November 2008 to January 2016...
November 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28688993/fat-demented-and-stupid-an-unrecognized-legacy-of-pediatric-urology
#12
REVIEW
Christopher S Cooper
The human body is an unfathomably intricate structure consisting of many connected and intertwined systems. This makes it impossible for therapeutic interventions to selectively target only one physiologic system without some impact or side effects on all the other systems. The resiliency of the human body modifies and disguises side effects, some of which may be undetectable for years and not apparent without scientific investigation. Pediatric urologists employ relatively few medications for the common conditions they treat and in general these consist of antibiotics, anticholinergics, and anesthetics...
August 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28638239/using-transfer-learning-for-improved-mortality-prediction-in-a-data-scarce-hospital-setting
#13
Thomas Desautels, Jacob Calvert, Jana Hoffman, Qingqing Mao, Melissa Jay, Grant Fletcher, Chris Barton, Uli Chettipally, Yaniv Kerem, Ritankar Das
Algorithm-based clinical decision support (CDS) systems associate patient-derived health data with outcomes of interest, such as in-hospital mortality. However, the quality of such associations often depends on the availability of site-specific training data. Without sufficient quantities of data, the underlying statistical apparatus cannot differentiate useful patterns from noise and, as a result, may underperform. This initial training data burden limits the widespread, out-of-the-box, use of machine learning-based risk scoring systems...
2017: Biomedical Informatics Insights
https://www.readbyqxmd.com/read/28623745/a-new-air-quality-monitoring-and-early-warning-system-air-quality-assessment-and-air-pollutant-concentration-prediction
#14
Zhongshan Yang, Jian Wang
Air pollution in many countries is worsening with industrialization and urbanization, resulting in climate change and affecting people's health, thus, making the work of policymakers more difficult. It is therefore both urgent and necessary to establish amore scientific air quality monitoring and early warning system to evaluate the degree of air pollution objectively, and predict pollutant concentrations accurately. However, the integration of air quality assessment and air pollutant concentration prediction to establish an air quality system is not common...
October 2017: Environmental Research
https://www.readbyqxmd.com/read/28592360/clinical-study-of-a-new-modified-early-warning-system-scoring-system-some-lingering-doubts
#15
Xianshi Zhou, Ye Ye, Guanghua Tang
No abstract text is available yet for this article.
June 1, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28566256/validating-the-performance-of-the-modified-early-obstetric-warning-system-multivariable-model-to-predict-maternal-intensive-care-unit-admission
#16
Helen M Ryan, Meghan A Jones, Beth A Payne, Sumedha Sharma, Anna M Hutfield, Tang Lee, U Vivian Ukah, Keith R Walley, Laura A Magee, Peter von Dadelszen
OBJECTIVES: To evaluate the performance of the Modified Early Obstetric Warning System (MEOWS) to predict maternal ICU admission in an obstetric population. DESIGN: Case-control study. SETTING: Two maternity units in Vancouver, Canada, one with ICU facilities, between January 1, 2000, and December 31, 2011. PATIENTS: Pregnant or recently delivered (≤6 weeks) women admitted to the hospital for >24 hours. Three control patients were randomly selected per case and matched for year of admission...
May 26, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28440868/improved-outcomes-after-successful-implementation-of-a-pediatric-early-warning-system-pews-in-a-resource-limited-pediatric-oncology-hospital
#17
Asya Agulnik, Lupe Nataly Mora Robles, Peter W Forbes, Doris Judith Soberanis Vasquez, Ricardo Mack, Federico Antillon-Klussmann, Monica Kleinman, Carlos Rodriguez-Galindo
BACKGROUND: Hospitalized pediatric oncology patients are at high risk of clinical decline and mortality, particularly in resource-limited settings. Pediatric early warning systems (PEWS) aid in the early identification of clinical deterioration; however, there are limited data regarding their feasibility or impact in low-resource settings. This study describes the successful implementation of PEWS at the Unidad Nacional de Oncología Pediátrica (UNOP), a pediatric oncology hospital in Guatemala, resulting in improved inpatient outcomes...
August 1, 2017: Cancer
https://www.readbyqxmd.com/read/28434059/early-warning-score-independently-predicts-adverse-outcome-and-mortality-in-patients-with-acute-pancreatitis
#18
Michael J Jones, Christopher P Neal, Wee Sing Ngu, Ashley R Dennison, Giuseppe Garcea
PURPOSE: The aim of this study was to compare the prognostic value of established scoring systems with early warning scores in a large cohort of patients with acute pancreatitis. METHODS: In patients presenting with acute pancreatitis, age, sex, American Society of Anaesthesiologists (ASA) grade, Modified Glasgow Score, Ranson criteria, APACHE II scores and early warning score (EWS) were recorded for the first 72 h following admission. These variables were compared between survivors and non-survivors, between patients with mild/moderate and severe pancreatitis (based on the 2012 Atlanta Classification) and between patients with a favourable or adverse outcome...
August 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/28385419/vital-signs-and-other-observations-used-to-detect-deterioration-in-pregnant-women-an-analysis-of-vital-sign-charts-in-consultant-led-uk-maternity-units
#19
G B Smith, R Isaacs, L Andrews, M Y K Wee, E van Teijlingen, D E Bick, V Hundley
BACKGROUND: Obstetric early warning systems are recommended for monitoring hospitalised pregnant and postnatal women. We decided to compare: (i) vital sign values used to define physiological normality; (ii) symptoms and signs used to escalate care; (iii) type of chart used; and (iv) presence of explicit instructions for escalating care. METHODS: One-hundred-and-twenty obstetric early warning charts and escalation protocols were obtained from consultant-led maternity units in the UK and Channel Islands...
May 2017: International Journal of Obstetric Anesthesia
https://www.readbyqxmd.com/read/28351349/development-and-validation-of-the-efficacy-safety-score-ess-a-novel-tool-for-postoperative-patient-management
#20
Erlend Skraastad, Johan Ræder, Vegard Dahl, Lars J Bjertnæs, Vladimir Kuklin
BACKGROUND: Several reports have shown that postoperative monitoring of general safety and quality issues, including pain treatment, after discharge from recovery is often non-systematic and inadequate. We suggest a new score with assessment of key recovery parameters, as a supportive tool for postoperative care and a call-out algorithm for need of extra help. The aim of this investigation was to validate the score. METHODS: After suggesting a prototype score from a pilot study in 182 postoperative patients, we performed a Delphi process by using international experts to create consensus on the final score contents and called the revised tool the Efficacy Safety Score (ESS)...
March 28, 2017: BMC Anesthesiology
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