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Céline Pasian, Raymond Azar, Denis Fouque
Protein energy wasting (PEW) is an independent factor associated with morbi-mortality in chronic kidney disease. Wasting is particularly common in chronic diseases of organs such as kidney disease with a major impact at the stage of dialysis. It covers 20 to 70% of patients diagnosed with chronic kidney disease according to the degree of evolution of the disease and the diagnostic method used patients. Mechanisms of PEW are based mainly on anorexia and metabolic abnormalities caused by kidney disease. Nutritional treatment differs depending on the stage of the kidney disease acute or chronic treated whether or not by dialysis...
October 17, 2016: Néphrologie & Thérapeutique
Corey Pew, Glenn K Klute
Amputees often experience soft tissue breakdown and discomfort from the high transverse plane shear stresses between the residual limb and prosthesis. To evaluate the effects of varying the transverse plane stiffness, a small sample population of lower limb amputees wore a novel variable stiffness torsion adapter (VSTA). Peak transverse plane moments were evaluated for three fixed stiffness levels (compliant: 0.30Nm/°, intermediate: 0.57Nm/°, stiff: 0.91Nm/°) while participants traversed five tasks of daily living that emphasize transverse plane motion including: straight walking for reference, 90° turns, 180° turns, a static reach test, and the L-Test of functional mobility...
October 4, 2016: Gait & Posture
Shannon N Acker, Beth Wathen, Genie E Roosevelt, Lauren R S Hill, Anna Schubert, Jenny Reese, Denis D Bensard, Ann M Kulungowski
Introduction The rapid response team (RRT) is a multidisciplinary team who evaluates hospitalized patients for concerns of nonemergent clinical deterioration. RRT evaluations are mandatory for children whose Pediatric Early Warning System (PEWS) score (assessment of child's behavior, cardiovascular and respiratory status) is ≥4. We aimed to determine if there were differences in characteristics of RRT calls between children who were admitted primarily to either medical or surgical services. We hypothesized that RRT activations would be called for less severely ill children with lower PEWS score on surgical services compared with children admitted to a medical service...
October 5, 2016: European Journal of Pediatric Surgery
Young Youl Hyun, Kyu-Beck Lee, Kook-Hwan Oh, Curie Ahn, Sue Kyung Park, Dong Wan Chae, Tae-Hyun Yoo, Kyu Hun Cho, Yong-Soo Kim, Young-Hwan Hwang
OBJECTIVE: Adiponectin (ADPN) has antiatherogenic, anti-inflammatory, and insulin-sensitizing effects. Serum ADPN levels are increased in patients with chronic kidney diseases (CKD), and higher ADPN is paradoxically a predictor of mortality in these patients. The aim of this study was to determine the association between serum ADPN levels and protein-energy wasting (PEW) in predialysis CKD. METHOD: We examined serum ADPN concentrations and PEW in 1303 patients from the KNOW-CKD (KoreaN Cohort Study for Outcome in Patients With Chronic Kidney Disease) study...
July 30, 2016: Nutrition
Maysa Venturoso Gongora Buckeridge Serra, Paula Rezende Camargo, José Eduardo Zaia, Maria Georgina Marques Tonello, Paulo Roberto Veiga Quemelo
BACKGROUND: The effect of physical exercise in the workplace (PEW) on health promotion of workers is contradictory. OBJECTIVE: To evaluate the effects of the PEW in musculoskeletal disorders (MSDs), perception of stress and quality of life in workers. METHODS: The participants were divided into two groups: control group (n = 46) including non-participant workers of the PEW program, and PEW group (n = 50) including workers who regularly participate in the exercise program...
October 6, 2016: International Journal of Occupational Safety and Ergonomics: JOSE
Ali Sharif, Muhammad Ashraf, Aqeel Javeed, Aftab Ahmed Anjum, Muhammad Furqan Akhtar, Bushra Akhtar, Ammara Saleem
Water pollution has been a major concern for agrarian societies like Pakistan. Pharmaceutical industries are amongst the foremost contributor to industrial waste. Present study addresses the generation of oxidative stress caused by 2 months exposure to pharmaceutical wastewater in rats and their response to oral treatment with vitamin E, a potent antioxidant. The rats were randomized into five groups (n = 5) named as negative control, pharmaceutical wastewater (PEW) 100 %, PEW 10 %, PEW 1 %, and PEW 100 % + vitamin E...
September 19, 2016: Environmental Science and Pollution Research International
Anastasia Markaki, Maria G Grammatikopoulou, Maria Venihaki, John Kyriazis, Kostas Perakis, Kostas Stylianou
OBJECTIVE: The aim of the study was to examine the prevalence of protein-energy wasting (PEW) in hemodialysis (HD) and peritoneal dialysis (PD) patients in our center and determine whether adiponectin and leptin are involved in the development of PEW. DESIGN: Prospective (18 months). SETTING: University Hospital of Heraklion, Crete, Greece. SUBJECTS: Seventy-four end-stage-renal-disease patients, 47 on HD and 27 on PD...
November 2016: Endocrinología y Nutrición: órgano de la Sociedad Española de Endocrinología y Nutrición
Adamasco Cupisti, Claudia D'Alessandro, Gian Marco Caselli
Nutritional abnormalities and physical inactivity are risk factors of increased morbidity and mortality in patients with ESRD. Identify and define malnutrition, in particular protein-energy depletion (PEW), is an important task in the management of renal patients. The aim of this multicenter observational study was to implement the assessment of nutritional status and functional capacity in patients on peritoneal dialysis, including tests and validated methods which are relatively easy to apply in daily clinical practice...
July 2016: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
Feng Zhao, Lishan Qiao, Feng Shi, Pew-Thian Yap, Dinggang Shen
Early diagnosis of autism spectrum disorder (ASD) is critical for timely medical intervention, for improving patient quality of life, and for reducing the financial burden borne by the society. A key issue in neuroimaging-based ASD diagnosis is the identification of discriminating features and then fusing them to produce accurate diagnosis. In this paper, we propose a novel framework for fusing complementary and discriminating features from different imaging modalities. Specifically, we integrate the Fisher discriminant criterion and local correlation information into the canonical correlation analysis (CCA) framework, giving a new feature fusion method, called Supervised Local CCA (SL-CCA), which caters specifically to local and global multimodal features...
August 17, 2016: Brain Imaging and Behavior
Masakazu Saitoh, Masumi Ogawa, Marcelo Rodrigues Dos Santos, Hisae Kondo, Kiichi Suga, Haruki Itoh, Yoichiro Tabata
Patients under hemodialysis present protein-energy wasting (PEW), which is related with higher mortality rates. The study aimed to determine whether intradialytic resistance exercise training could improve physical performance, physical activity, and PEW in hemodialysis patients. In single center study, 75 hemodialysis patients were enrolled in an intradialytic resistance exercise training consisting of 20 min of adapted leg press, with a gymnastic ball, 3 days/week, during 9 months on the same day of hemodialysis therapy...
August 15, 2016: Therapeutic Apheresis and Dialysis
Geovana Martin-Alemañy, Rafael Valdez-Ortiz, Guadalupe Olvera-Soto, Irma Gomez-Guerrero, Guillermo Aguire-Esquivel, Guillermo Cantu-Quintanilla, Juan Carlos Lopez-Alvarenga, Paola Miranda-Alatriste, Angeles Espinosa-Cuevas
BACKGROUND: Protein-energy wasting (PEW) is common in patients undergoing hemodialysis (HD). Studies have assessed the positive effect of oral nutritional supplementation (ONS) or resistance exercise (RE) on nutritional status (NS) markers in patients undergoing HD. METHODS: The aim of this study was to assess the effect of ONS and RE on NS and the quality of life (QOL) of 36 patients undergoing HD. In a randomized clinical trial, patients were divided into the following two groups: a control group (ONS) that received a can of ONS during their HD sessions and an intervention group (ONS + RE) that received a can of ONS and underwent a 40-min session of RE during their HD sessions...
October 2016: Nephrology, Dialysis, Transplantation
Haiyong Wu, Geng Chen, Yan Jin, Dinggang Shen, Pew-Thian Yap
Global tractography estimates brain connectivity by organizing signal-generating fiber segments in an optimal configuration that best describes the measured diffusion-weighted data, promising better stability than local greedy methods with respect to imaging noise. However, global tractography is computationally very demanding and requires computation times that are often prohibitive for clinical applications. We present here a reformulation of the global tractography algorithm for fast parallel implementation amendable to acceleration using multi-core CPUs and general-purpose GPUs...
2016: Frontiers in Neuroinformatics
Katherine L Doll, Lecia L Pewe, Samarchith P Kurup, John T Harty
No abstract text is available yet for this article.
August 1, 2016: Journal of Immunology: Official Journal of the American Association of Immunologists
Lydia Aston, Caron Eyre, Michelle McLoughlin, Rachel Shaw
The objective was to identify evidence to support use of specific harms for the development of a children and young people's safety thermometer (CYPST). We searched PubMed, Web of Knowledge, and Cochrane Library post-1999 for studies in pediatric settings about pain, skin integrity, extravasation injury, and use of pediatric early warning scores (PEWS). Following screening, nine relevant articles were included. Convergent synthesis methods were used drawing on thematic analysis to combine findings from studies using a range of methods (qualitative, quantitative, and mixed methods)...
2016: Healthcare (Basel, Switzerland)
Phillip Seitz
History and Reconstruction is an interdisciplinary project to assess the impact of African American history education for black men. Under the theory of trauma recovery, leading scholars of African American history worked with a group of ten ex-offenders, supported by the services of a psychologist and an African American cultural expert and storyteller. Results based on psychological testing and qualitative feedback showed that history can be a catalyst for personal development and transformation. It also demonstrated that difficult history can be taught and assimilated for audience benefit...
May 2016: Public Historian
Gerald B Denny, Serpil M Deger, Guanhua Chen, Aihua Bian, Feng Sha, Cindy Booker, Jaclyn T Kesler, Sthuthi David, Charles D Ellis, T Alp Ikizler
BACKGROUND: Protein energy wasting (PEW) is common in patients undergoing maintenance hemodialysis (MHD) and closely associated with poor outcomes. Insulin resistance and associated alterations in amino acid metabolism are potential pathways leading to PEW. We hypothesized that the measurement of leucine disposal during a hyperinsulinemic- euglycemic-euaminoacidemic clamp (HEAC) procedure would accurately measure the sensitivity to insulin for its actions on concomitant carbohydrate and protein metabolism in MHD patients...
2016: BMC Nutrition
Pew-Thian Yap, Yong Zhang, Dinggang Shen
Sparse estimation techniques are widely utilized in diffusion MRI (DMRI). In this paper, we present an algorithm for solving the `0 sparse-group estimation problem and apply it to the tissue signal separation problem in DMRI. Our algorithm solves the `0 problem directly, unlike existing approaches that often seek to solve its relaxed approximations. We include the mathematical proofs showing that the algorithm will converge to a solution satisfying the first-order optimality condition within a finite number of iterations...
July 7, 2016: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
Yuyao Zhang, Feng Shi, Guorong Wu, Li Wang, Pew-Thian Yap, Dinggang Shen
Brain atlases are an essential component in understanding the dynamic cerebral development, especially for the early postnatal period. However, longitudinal atlases are rare for infants, and the existing ones are generally limited by their fuzzy appearance. Moreover, since longitudinal atlas construction is typically performed independently over time, the constructed atlases often fail to preserve temporal consistency. This problem is further aggravated for infant images since they typically have low spatial resolution and insufficient tissue contrast...
July 7, 2016: IEEE Transactions on Medical Imaging
A Sabatino, G Regolisti, T Karupaiah, S Sahathevan, B K Sadu Singh, B H Khor, N Salhab, M Karavetian, A Cupisti, E Fiaccadori
BACKGROUND & AIMS: Protein-Energy Wasting (PEW) is the depletion of protein/energy stores observed in the most advanced stages of Chronic Kidney Disease (CKD). PEW is highly prevalent among patients on chronic dialysis, and is associated with adverse clinical outcomes, high morbidity/mortality rates and increased healthcare costs. This narrative review was aimed at exploring the pathophysiology of PEW in end-stage renal disease (ESRD) on hemodialysis. The main aspects of nutritional status evaluation, intervention and monitoring in this clinical setting were described, as well as the current approaches for the prevention and treatment of ESRD-related PEW...
June 18, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
(no author information available yet)
The aim of this retrospective study was to determine if paediatric early warning scores (PEWS) Brighton and COAST could predict serious illness in children attending the ED.
June 10, 2016: Emergency Nurse: the Journal of the RCN Accident and Emergency Nursing Association
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