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https://www.readbyqxmd.com/read/29663425/experimental-investigation-of-linac-angles-and-floor-scatter-dose-contributions-using-cherenkov-imaging-improving-total-skin-electron-therapy-treatment-geometries
#1
Jacqueline M Andreozzi, Petr Brůža, Irwin I Tendler, Karen E Mooney, Lesley A Jarvis, Jochen Cammin, Harold Li, Brian W Pogue, David J Gladstone
PURPOSE: The purpose of this study was to identify the optimal treatment geometry for total skin electron therapy (TSET) using a new optimization metric from Cherenkov image analysis, and to investigate the sensitivity of the Cherenkov imaging method to floor scatter effects in this unique treatment setup. METHODS: Cherenkov imaging using an intensified charge coupled device (ICCD) was employed to measure the relative surface dose distribution as a 2D image in the total skin electron treatment plane...
April 16, 2018: Medical Physics
https://www.readbyqxmd.com/read/29594143/a-case-of-crescentic-glomerulonephritis-complicated-with-hypocomplementemic-urticarial-vasculitis-syndrome-and-anca-associated-vasculitis
#2
Marenao Tanaka, Norihito Moniwa, Tomohiro Mita, Toshiyuki Tobisawa, Tamaki Matsumoto, Atsushi Mochizuki, Tomohisa Yamashita, Toshiyuki Yano, Masato Furuhashi, Tetsuji Miura
Systemic urticaria in a 64-year-old woman was diagnosed as leukocytoclastic vasculitis by a punch biopsy of the skin. Her physical findings improved after prescription of prednisolone at a dose of 20 mg/day, but the skin rash relapsed with renal dysfunction, proteinuria, and hematuria when the dose of prednisolone was reduced over a period of 9 months to 1 mg/day. She was admitted to our institute for further examination, when urinary protein and plasma creatinine levels were 0.8 g/day and 1.7 mg/dL, respectively...
September 2017: Case Reports in Nephrology and Dialysis
https://www.readbyqxmd.com/read/29588437/time-gated-scintillator-imaging-for-real-time-optical-surface-dosimetry-in-total-skin-electron-therapy
#3
Petr Bruza, Sarah L Gollub, Jacqueline M Andreozzi, Irwin I Tendler, Benjamin B Williams, Lesley A Jarvis, David J Gladstone, Brian W Pogue
To measure surface dose by remote time-gated imaging of plastic scintillators.
 
 Methods: A novel technique for time-gated, intensified camera imaging of scintillator emission was demonstrated, and key parameters influencing the signal were analyzed, including distance, angle and thickness. A set of scintillator samples was calibrated by using thermo-luminescence detector response as reference. Examples of use in total skin electron therapy are described.
 
 Results: The data showed excellent room light rejection (signal-to-noise ratio of scintillation SNR ≈ 470), ideal scintillation dose response linearity, and 2% dose rate error...
March 28, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29580524/investigation-on-complex-coacervation-between-fish-skin-gelatin-from-cold-water-fish-and-gum-arabic-phase-behavior-thermodynamic-and-structural-properties
#4
Yong Li, Xiyue Zhang, Yu Zhao, Jie Ding, Songyi Lin
The study is aimed to investigate phase behavior, thermodynamic, and structural properties based on complex coacervation between fish skin gelatin (FSG) from cold-water fish and gum arabic (GA). Phase separation behavior between FSG and GA was investigated as a function of pH through varying mixing ratios from 4:1 to 1:4 at 25 °C and 1.0 wt% of total biopolymer concentration. The turbidity of FSG-GA mixture reached the maximum (1.743) at the 1:2 of mixing ratio and pHopt 3.5, and stabilized at zero. Then physicochemical properties of FSG-GA coacervates at pHopt 3...
May 2018: Food Research International
https://www.readbyqxmd.com/read/29578144/transdermal-fentanyl-for-cancer-pain-trial-sequential-analysis-of-3406-patients-from-35-randomized-controlled-trials
#5
Dong-Dong Wang, Ting-Ting Ma, Hua-Dong Zhu, Cong-Bin Peng
Objective: The aim of this study was to assess the effectiveness and safety of transdermal fentanyl for the treatment of moderate or severe cancer-related pain. Materials and Methods: Electronic databases including PubMed, Embase, the Cochrane Library, Web of Science, Chinese National Knowledge Infrastructure, the Chinese Biomedical Literature Database, and Chongqing Weipu and Wanfang Database were searched for relevant studies published prior to January 2015. Only randomized controlled trials on the use of the transdermal fentanyl patch for the treatment of cancer pain were selected...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29577562/dermatological-manifestations-in-hemodialysis-patients-in-iran-a-systematic-review-and-meta-analysis
#6
Hamid Asayesh, Niloofar Peykari, Mohammad Pavaresh-Masoud, Mohammad Esmaeili Abdar, Ramin Tajbakhsh, Seyed Mojtaba Mousavi, Shirin Djalalinia, Mehdi Noroozi, Mostafa Qorbani, Armita Mahdavi-Gorabi
BACKGROUND: Dermatologic complications are common in patients with end-stage renal disease and also have a high diversity. OBJECTIVES: This meta-analysis reviews prevalence of dermatological manifestations among hemodialysis patients in Iran. MATERIALS AND METHODS: Using PubMed and NLM Gateway (for MEDLINE), Institute of Scientific Information (ISI), and SCOPUS as the main international electronic data sources, and Iran-Medex, Irandoc, and Scientific Information Database, as the main domestic databases with systematic search capability, we systematically searched surveys, papers, and reports on the prevalence of dermatological manifestations (until February 2016)...
March 25, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29573271/a-study-of-skin-disease-spectrum-occurring-in-angola-phototype-v-vi-population-in-luanda
#7
David A De Luca, Ziv Maianski, Michael Averbukh
BACKGROUND: Prevalence of skin diseases in Luanda (Angola) is unknown, and publications are barely found in the literature. We aim to describe, for the first time, the frequency of skin disease spectrum in phototype V-VI Angolan population in Luanda City. METHODS: We included Fitzpatrick phototype V-VI Angolan patients who consulted the Dermatology Unit in Luanda Medical Center during a 1-year period. Medical information was recovered from the electronic database, and diagnoses were based on ICD-10...
March 24, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29552795/first-application-of-hemi-body-electron-beam-irradiation-for-kaposi-sarcoma-at-the-lower-extremities-in-children
#8
Kalliopi Platoni, Stefanos Diamantopoulos, Maria Dilvoi, Panagiotis Delinikolas, Efrosyni Kypraiou, Efstathios Efstathopoulos, Vassilis Kouloulias
Kaposi's sarcoma (KS) is a systemic neoplastic disease that can present cutaneous symptoms and is usually treated with a systematic approach due to its extent. Due to its radiosensitivity, radiotherapy is considered one of its main treatments, for palliation and local control of the skin and mucosal lesions. The aim of this paper was to report the first case of KS treated by hemi-body electron irradiation protocol in Greece. A fractionated 40 Gy hemi-body electron irradiation was prescribed to a 60-year-old male patient with KS at his legs...
January 2018: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/29523904/risk-factor-analysis-for-survival-of-becker-type-expander-in-immediate-breast-reconstruction
#9
Sukru Yazar, E Cigdem Karadag, Altug Altinkaya, Halil Kara, Cihan Uras
BACKGROUND: Breast reconstruction with a Becker-type expander is a common technique following mastectomy. However, inconsistency remains in the literature regarding risk factors for the survival of a Becker-type expander following immediate breast reconstruction. This study's purpose is to investigate possible risk factors for the Becker-type expander survival and to evaluate the complications related to expander removal following immediate breast reconstruction. METHODS: We performed a retrospective chart review of consecutive women who underwent a mastectomy followed by immediate breast reconstruction with a Becker-type expander from November 2010 to November 2016...
March 9, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29519403/a-novel-hemi-body-irradiation-technique-using-electron-beams-hbie
#10
Panagiotis Delinikolas, Georgios Patatoukas, Vasilios Kouloulias, Maria Dilvoi, Agapi Plousi, Efstathios Efstathopoulos, Kalliopi Platoni
PURPOSE: Certain radiation responsive skin diseases may develop symptoms on the upper or the lower half of the body. The concept of a novel Hemi-Body Electron Irradiation (HBIe- ) technique, described in this work, provides a low cost, LINAC based, intermediate treatment option in between extremely localized and Total Skin irradiation techniques. MATERIALS AND METHODS: The HBIe- technique, developed in our department, incorporates a custom crafted treatment chamber equipped with adjustable Pb shielding and a single electron beam in extended Source-Skin Distance (SSD) setup...
February 2018: Physica Medica: PM
https://www.readbyqxmd.com/read/29487915/skin-interfaced-systems-for-sweat-collection-and-analytics
#11
REVIEW
Jungil Choi, Roozbeh Ghaffari, Lindsay B Baker, John A Rogers
Recent interdisciplinary advances in materials, mechanics, and microsystem designs for biocompatible electronics, soft microfluidics, and electrochemical biosensors establish the foundations for emerging classes of thin, skin-interfaced platforms capable of capturing, storing, and performing quantitative, spatiotemporal measurements of sweat chemistry, instantaneous local sweat rate, and total sweat loss. This review summarizes scientific and technical progress in this area and highlights the implications in real time and ambulatory modes of deployment during physical activities across a broad range of contexts in clinical health, physiology research, fitness/wellness, and athletic performance...
February 2018: Science Advances
https://www.readbyqxmd.com/read/29482765/safety-and-tolerability-of-prescription-omega-3-fatty-acids-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#12
Cheng-Ho Chang, Ping-Tao Tseng, Nai-Yu Chen, Pei-Chin Lin, Pao-Yen Lin, Jane Pei-Chen Chang, Feng-Yu Kuo, Jenshinn Lin, Ming-Chang Wu, Kuan-Pin Su
BACKGROUND: Omega-3 fatty acids [eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)] are widely recommended for health promotion. Over the last decade, prescription omega-3 fatty acid products (RxOME3FAs) have been approved for medical indications. Nonetheless, there is no comprehensive analysis of safety and tolerability of RxOME3FAs so far. METHODS: A systematic review of randomized controlled trials (RCTs) was carried out based on searches in six electronic databases...
February 2018: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/29479666/clinical-characteristics-and-management-of-patients-with-rosacea-in-a-tertiary-dermatology-center-in-singapore-from-2009-to-2013
#13
Kah Wai Cheong, Yik Weng Yew, Yi Chun Lai, Roy Chan
INTRODUCTION: Rosacea is a common chronic facial skin disease. A multiethnic society such as Singapore provides an opportunity to evaluate the demographic characteristics and their impact on clinical outcome in rosacea. AIMS: The aim of this study was to evaluate characteristics and outcome of rosacea in a multiracial population in Singapore. METHODS: Records of all rosacea patients between January 2009 and December 2013 were retrospectively retrieved from the electronic medical records (EMR)...
February 26, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29472269/understanding-the-gender-gap-in-antibiotic-prescribing-a-cross-sectional-analysis-of-english-primary-care
#14
David R M Smith, F Christiaan K Dolk, Timo Smieszek, Julie V Robotham, Koen B Pouwels
OBJECTIVES: To explore the causes of the gender gap in antibiotic prescribing, and to determine whether women are more likely than men to receive an antibiotic prescription per consultation. DESIGN: Cross-sectional analysis of routinely collected electronic medical records from The Health Improvement Network (THIN). SETTING: English primary care. PARTICIPANTS: Patients who consulted general practices registered with THIN between 2013 and 2015...
February 22, 2018: BMJ Open
https://www.readbyqxmd.com/read/29467923/synthetic-analysis-of-associations-between-il-10-polymorphisms-and-skin-cancer-risk
#15
Hongbo Zhao, Jiaoli Yang, Zhenzhen Yu, Hui Shen, Xinlin Huang, Mi Zhang, Teng Long, A Cailing, Wenhui Wang
The current study was designed to quantitatively summarize the evidence for the strength of the associations between common IL-10 functional polymorphisms and skin cancer risk. Relevant publications concerning the associations between common IL-10 functional polymorphisms(-1082G>A, -819C>T and -592C>A) and skin cancer were retrieved by a comprehensive electronic literature search in PubMed, Web of Science, EBSCO, Embase, China National Knowledge Infrastructure, Wanfang, Chinese Biomedical Database (CBM)...
January 23, 2018: Oncotarget
https://www.readbyqxmd.com/read/29411650/formulation-and-in-vivo-assessment-of-terconazole-loaded-polymeric-mixed-micelles-enriched-with-cremophor-el-as-dual-functioning-mediator-for-augmenting-physical-stability-and-skin-delivery
#16
Wessam H Abd-Elsalam, Sally A El-Zahaby, Abdulaziz M Al-Mahallawi
The aim of the current study was to formulate terconazole (TCZ) loaded polymeric mixed micelles (PMMs) incorporating Cremophor EL as a stabilizer and a penetration enhancer. A 23 full factorial design was performed using Design-Expert® software for the optimization of the PMMs which were formulated using Pluronic P123 and Pluronic F127 together with Cremophor EL. To confirm the role of Cremophor EL, PMMs formulation lacking Cremophor EL was prepared for the purpose of comparison. Results showed that the optimal PMMs formulation (F7, where the ratio of total Pluronics to drug was 40:1, the weight ratio of Pluronic P123 to Pluronic F127 was 4:1, and the percentage of Cremophor EL in aqueous phase was 5%) had a high micellar incorporation efficiency (92...
November 2018: Drug Delivery
https://www.readbyqxmd.com/read/29403541/ivig-for-apparently-autoimmune-small-fiber-polyneuropathy-first-analysis-of-efficacy-and-safety
#17
Xiaolei Liu, Roi Treister, Magdalena Lang, Anne Louise Oaklander
Objectives: Small-fiber polyneuropathy (SFPN) has various underlying causes, including associations with systemic autoimmune conditions. We have proposed a new cause; small-fiber-targeting autoimmune diseases akin to Guillain-Barré and chronic inflammatory demyelinating polyneuropathy (CIDP). There are no treatment studies yet for this 'apparently autoimmune SFPN' (aaSFPN), but intravenous immunoglobulin (IVIg), first-line for Guillain-Barré and CIDP, is prescribed off-label for aaSFPN despite very high cost...
2018: Therapeutic Advances in Neurological Disorders
https://www.readbyqxmd.com/read/29399830/electronic-device-generated-light-increases-reactive-oxygen-species-in-human-fibroblasts
#18
Evan Austin, Amy Huang, Tony Adar, Erica Wang, Jared Jagdeo
OBJECTIVES: Our skin is constantly exposed to light from solar radiation and electronic devices, which impact skin physiology and aging. The biological altering properties of ultraviolet (UV) solar radiation on skin have been well established. There is significant scientific and public interest on the effects of electronic device generated light (EDGL) on skin. Currently, the effects of EDGL on skin are largely unknown. EDGL includes UV, visible, and infrared light from consumer electronics such as smartphones, computers, and televisions...
February 5, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29384856/use-of-noncontact-infrared-thermography-to-measure-temperature-in-children-in-a-triage-room
#19
Emel Ataş Berksoy, Özlem Bağ, Selçuk Yazici, Tanju Çelik
We compared the accuracy and utility of 3 infrared (IFR) thermographs fitted with axillary digital thermometers used to measure temperature in febrile and afebrile children admitted to an emergency triage room.A total of 184 febrile and 135 afebrile children presenting to a triage room were consecutively evaluated. Axillary temperature was recorded using a digital electronic thermometer. Simultaneously, IFR skin scans were performed on the forehead, the neck (over the carotid artery), and the nape by the same nurse...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29376219/selenium-for-preventing-cancer
#20
REVIEW
Marco Vinceti, Tommaso Filippini, Cinzia Del Giovane, Gabriele Dennert, Marcel Zwahlen, Maree Brinkman, Maurice Pa Zeegers, Markus Horneber, Roberto D'Amico, Catherine M Crespi
BACKGROUND: This review is the third update of the Cochrane review "Selenium for preventing cancer". Selenium is a naturally occurring element with both nutritional and toxicological properties. Higher selenium exposure and selenium supplements have been suggested to protect against several types of cancer. OBJECTIVES: To gather and present evidence needed to address two research questions:1. What is the aetiological relationship between selenium exposure and cancer risk in humans?2...
January 29, 2018: Cochrane Database of Systematic Reviews
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