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https://www.readbyqxmd.com/read/28222994/palliative-care-and-palliative-radiation-therapy-education-in-radiation-oncology-a-survey-of-us-radiation-oncology-program-directors
#1
Randy L Wei, Lauren E Colbert, Joshua Jones, Margarita Racsa, Gabrielle Kane, Steve Lutz, Neha Vapiwala, Kavita V Dharmarajan
PURPOSE: The purpose of this study was to assess the state of palliative and supportive care (PSC) and palliative radiation therapy (RT) educational curricula in radiation oncology residency programs in the United States. METHODS AND MATERIALS: We surveyed 87 program directors of radiation oncology residency programs in the United States between September 2015 and November 2015. An electronic survey on PSC and palliative RT education during residency was sent to all program directors...
December 1, 2016: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28208630/cocoa-and-grape-seed-byproducts-as-a-source-of-antioxidant-and-anti-inflammatory-proanthocyanidins
#2
María De La Luz Cádiz-Gurrea, Isabel Borrás-Linares, Jesús Lozano-Sánchez, Jorge Joven, Salvador Fernández-Arroyo, Antonio Segura-Carretero
Phenolic compounds, which are secondary plant metabolites, are considered an integral part of the human diet. Physiological properties of dietary polyphenols have come to the attention in recent years. Especially, proanthocyanidins (ranging from dimers to decamers) have demonstrated potential interactions with biological systems, such as antiviral, antibacterial, molluscicidal, enzyme-inhibiting, antioxidant, and radical-scavenging properties. Agroindustry produces a considerable amount of phenolic-rich sources, and the ability of polyphenolic structures to interacts with other molecules in living organisms confers their beneficial properties...
February 10, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28191804/does-alternative-and-traditional-wasam-local-cautery-therapy-facilitate-an-early-and-more-extensive-locoregional-metastasis-of-breast-cancer
#3
(no author information available yet)
INTRODUCTION: A large heterogeneous group of unproven remedies exist to treat cancer in both developed and developing countries. Some of these remedies often do more harm than good to the patients. The traditional medicine is the sum total of the knowledge, skills, and practices based on the theories, beliefs, and experiences indigenous to different cultures. The traditional medicine in Oman is based on herbal treatment and skin treatment (massage, Cupping and skin burn "cautery" treatment-known as Wasam or Kaiy)...
September 2016: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/28177974/optimizing-radiotherapy-for-keloids-a-meta-analysis-systematic-review-comparing-recurrence-rates-between-different-radiation-modalities
#4
Peter Mankowski, Jonathan Kanevsky, Jared Tomlinson, Alina Dyachenko, Mario Luc
BACKGROUND: The high recurrence rate of keloids has lead to the use of multiple treatment adjuncts to improve cosmetic outcomes after surgery. To date, there has been no single, standardized modality agreed upon to produce the best results. The purpose of this study was to review the radiation-based treatments (brachytherapy, electron beam and X-ray) used for keloid management and compare their outcomes. METHODS: A literature review was performed from 1942 to October 2014 using the databases: PubMed database of the National Center of Biotechnology Information, MEDLINE, Biosis, Embase, Google scholar, and Cochrane database...
February 8, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28133821/total-skin-electron-therapy-as-treatment-for-epitheliotropic-lymphoma-in-a-dog
#5
Domenico Santoro, Lyndsay Kubicek, Bo Lu, William Craft, Julia Conway
BACKGROUND: Mycosis fungoides (MF) is an uncommon cutaneous neoplasm in dogs. Treatment options are limited. Total skin electron therapy (TSET) has been suggested as a possible therapy for canine MF. OBJECTIVE: To describe the use of TSET as palliative treatment for MF in a dog. RESULTS: An adult dog, previously diagnosed with nonepidermolytic ichthyosis, was presented with generalized erythroderma, alopecia and erosions. Histopathology revealed a densely cellular, well-demarcated, unencapsulated infiltrate extending from the epidermis to the mid-dermis compatible with MF...
January 29, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28133514/anti-melanogenic-effect-of-oenothera-laciniata-methanol-extract-in-melan-a-cells
#6
Su Eun Kim, Chae Myoung Lee, Young Chul Kim
We evaluated the antioxidant activity and anti-melanogenic effects of Oenothera laciniata methanol extract (OLME) in vitro by using melan-a cells. The total polyphenol and flavonoid content of OLME was 66.3 and 19.0 mg/g, respectively. The electron-donating ability, 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical-scavenging activity, and superoxide dismutase (SOD)-like activity of OLME (500 μg/mL) were 94.5%, 95.6%, and 63.6%, respectively. OLME and arbutin treatment at 50 μg/mL significantly decreased melanin content by 35...
January 2017: Toxicological Research
https://www.readbyqxmd.com/read/28132406/recommendations-for-treatment-in-folliculotropic-mycosis-fungoides-report-of-the-dutch-cutaneous-lymphoma-group
#7
S van Santen, R van Doorn, K J Neelis, L A Daniëls, B Horváth, M S Bruijn, C J G Sanders, M M van Rossum, E R M de Haas, J C J M Veraart, M W Bekkenk, M H Vermeer, R Willemze
BACKGROUND: Folliculotropic mycosis fungoides (FMF) is an aggressive variant of mycosis fungoides (MF) and generally less responsive to standard skin-directed therapies (SDTs). Recent studies distinguished an indolent (early-stage FMF) and a more aggressive (advanced-stage FMF) subgroup. The optimal treatment for both subgroups needs still to be defined. OBJECTIVES: Evaluation of initial treatment results in patients with early- and advanced-stage FMF. METHODS: 203 Patients (84 early-stage, 102 advanced-stage, 17 extracutaneous FMF), included in the Dutch Cutaneous Lymphoma Registry between 1985 and 2014 were studied...
January 28, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28114648/patient-provider-and-combined-interventions-for-managing-osteoarthritis-in-primary-care-a-cluster-randomized-trial
#8
Kelli D Allen, Eugene Z Oddone, Cynthia J Coffman, Amy S Jeffreys, Hayden B Bosworth, Ranee Chatterjee, Jennifer McDuffie, Jennifer L Strauss, William S Yancy, Santanu K Datta, Leonor Corsino, Rowena J Dolor
Background: A single-site study showed that a combined patient and provider intervention improved outcomes for patients with knee osteoarthritis, but it did not assess separate effects of the interventions. Objective: To examine whether patient-based, provider-based, and patient-provider interventions improve osteoarthritis outcomes. Design: Cluster randomized trial with assignment to patient, provider, and patient-provider interventions or usual care...
January 17, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28112800/comparison-of-the-paper-based-and-electronic-versions-of-the-dermatology-life-quality-index-dlqi-evidence-of-equivalence
#9
F M Ali, N Johns, A Finlay, M S Salek, V Piguet
BACKGROUND: The use of patient-reported outcome measures in electronic format has been increasing. However, these formats are usually not validated or compared to the original paper-based formats, so there is no evidence that they are completed in the same way. OBJECTIVES: The aim of this study was to compare the conventional paper version and a web-based application version (iPad(®) ) of the DLQI to assess equivalence of scores. METHODS: The study employed a randomized cross-over design using a within-subjects comparison of the two formats of the questionnaire...
January 23, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28107773/safety-and-effectiveness-of-tofogliflozin-in-elderly-japanese-patients-with-type-2-diabetes-mellitus-a-post-marketing-study-j-step-el-study
#10
Kazunori Utsunomiya, Naoki Shimmoto, Masayuki Senda, Yuji Kurihara, Ryoji Gunji, Shoko Fujii, Seigo Kakiuchi, Hisataka Fujiwara, Hiroyuki Kameda, Masahiro Tamura, Kohei Kaku
AIMS/INTRODUCTION: While sodium glucose cotransporter 2 inhibitors are a promising treatment for type 2 diabetes mellitus, they are associated with concerns about specific adverse drug reactions. We conducted a 1-year post-marketing study of tofogliflozin, a novel agent in this class, in Japanese elderly patients with type 2 diabetes mellitus. MATERIALS AND METHODS: This was a prospective, observational, and multicenter post-marketing study conducted in the context of routine clinical practice...
January 20, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28103990/-effects-of-human-amniotic-epithelial-stem-cells-derived-exosomes-on-healing-of-wound-with-full-thickness-skin-defect-in-rats
#11
B Zhao, G F Wu, Y J Zhang, W Zhang, F F Yang, D Xiao, K X Zeng, J H Shi, L L Su, D H Hu
Objective: To investigate the effects of human amniotic epithelial stem cells-derived exosomes on healing of wound with full-thickness skin defect in rats. Methods: (1) Human amniotic epithelial stem cells were isolated from the amnion tissue of 5 full-term pregnant women in Department of Obstetrics of our hospital by the method of trypsin digestion, and their morphology was observed. The third passage of cells were stained with rhodamine-phalloidin for cytoskeleton observation. The third passage of cells were identified with flow cytometry through the detection of expressions of cell surface markers CD29, CD31, CD34, CD90, CD105, SSEA3, SSEA4 and immunity-related marker human leukocyte antigen-D related site (HLA-DR)...
January 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28093639/the-effectiveness-of-radiotherapy-for-leukemia-cutis
#12
Khaled Elsayad, Michael Oertel, Uwe Haverkamp, Hans Theodor Eich
BACKGROUND: Leukemia cutis (LC) is a rare clinical presentation of leukemia that is associated with poor prognosisabs. To date, the value of radiotherapy (RT) for the treatment of LC remains controversial. Therefore, the aim of this study was to analyse the effectiveness of various RT doses for LC. METHODS AND MATERIALS: Between January 2000 and January 2016, 13 patients underwent RT at our institution after exhibiting progressive disease following other treatment modalities...
January 16, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28056600/the-use-of-teledermoscopy-in-the-accurate-identification-of-cancerous-skin-lesions-in-the-adult-population-a-systematic-review
#13
Amy F Bruce, Jennifer A Mallow, Laurie A Theeke
Background The use of teledermoscopy in the diagnostic management of pre-cancerous and cancerous skin lesions involves digital dermoscopic images transmitted over telecommunication networks via email or web applications. Teledermoscopy may improve the accuracy in clinical diagnoses of melanoma skin cancer if integrated into electronic medical records and made available to rural communities, potentially leading to decreased morbidity and mortality. Objective and method The purpose of this paper is to present a systematic review of evidence on the use of teledermoscopy to improve the accuracy of skin lesion identification in adult populations...
January 1, 2017: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/28051327/are-there-potential-safety-issues-concerning-the-safe-usage-of-electronic-personal-tracking-devices-the-experience-of-a-multi-sport-elite-club
#14
Daniel Medina, Eduard Pons, Antonio Gomez, Marc Guitart, Andres Martin, Jairo Vazquez-Guerrero, Ismael Camenforte, Berta Carles, Roger Font
Despite approval of the use of electronic personal tracking devices (EPTD) during competition by the International Football Association Board (IFAB), other team sport organizations and leagues have banned its use due to "safety concerns", with no evidence to support this assertion. The aim of the current brief report is to provide empirical evidence to support the wide-spread usage across all sports by examining safety issues concerning the use of EPTD in a multi-team sports club. A total of 5 outdoor football teams (first team, second team, under 19, under 18 and first team female) and 3 indoor multi-sport (basketball, futsal and handball) teams have been monitored; accounting for a total of 63...
January 4, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28049509/hyperbaric-oxygen-therapy-for-a-refractory-skin-ulcer-after-radical-mastectomy-and-radiation-therapy-a-case-report
#15
Mitsuhiro Enomoto, Kazuyoshi Yagishita, Kae Okuma, Takuya Oyaizu, Yasushi Kojima, Atsushi Okubo, Takuma Maeda, Satoko Miyamoto, Atsushi Okawa
BACKGROUND: Radiation therapy is performed as an adjuvant therapy when indicated following surgical resection of malignant tumors. However, radiation exposure induces acute or chronic dermatitis, depending on the radiation dose, interval, tissue volume, or irradiated area of the body. Radiation-induced skin ulcers and osteomyelitis of the underlying bone are intractable late-stage complications of radiation therapy, and often require reconstructive surgery to cover exposed tissue. Hyperbaric oxygen therapy has been suggested as a treatment for delayed radiation injury with soft tissue and bony necrosis...
January 4, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28048817/su-f-t-83-infant-total-skin-electron-therapy-using-five-fields-technique
#16
H Saleh, T Howlin, V Massey
PURPOSE: We were presented with a 9 month old boy with Relapsed Acute Myeloid Leukemia (AML) involving the skin. The plan was to treat the entire skin using 6 MeV electrons with the infant under complete anesthesia. The purpose of this work is to commission the 6 MeV electron beam and to develop a technique that can be used to deliver total skin dose to infants with minimal patient immobilization. METHODS: A baby mannequin phantom that mimics the child's length was used to determine the best technique to treat the infant...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048596/su-f-t-248-fmea-risk-analysis-implementation-aapm-tg-100-in-total-skin-electron-irradiation-technique
#17
B Ibanez-Rosello, J Bautista-Ballesteros, J Bonaque, J Perez-Calatayud, A Gonzalez-Sanchis, J Lopez-Torrecilla, L Brualla-Gonzalez, T Garcia-Hernandez, A Vicedo-Gonzalez, D Granero, A Serrano, B Borderia, C Solera, J Rosello
PURPOSE: Total Skin Electron Irradiation (TSEI) is a radiotherapy treatment which involves irradiating the entire body surface as homogeneously as possible. It is composed of an extensive multi-step technique in which quality management requires high consumption of resources and a fluid communication between the involved staff, necessary to improve the safety of treatment. The TG-100 proposes a new perspective of quality management in radiotherapy, presenting a systematic method of risk analysis throughout the global flow of the stages through the patient...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048019/su-f-t-76-total-skin-electron-therapy-an-end-to-end-examination-of-the-absolute-dosimetry-with-a-rando-phantom
#18
G Cui, J Ha, S Zhou, J Cui, A Shiu
PURPOSE: To examine and validate the absolute dose for total skin electron therapy (TSET) through an end-to-end test with a Rando phantom using optically stimulated luminescent dosimeters (OSLDs) and EBT3 radiochromic films. METHODS: A Varian Trilogy linear accelerator equipped with the special procedure 6 MeV HDTSe- was used to perform TSET irradiations using a modified Stanford 6-dual-field technique. The absolute dose was calibrated using a Markus ion chamber at a reference depth of 1...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047639/su-g-tep1-13-reclined-total-skin-electron-treatment-technique
#19
D Mathew, B Gerbi
PURPOSE: The purpose is to describe a new reclined technique for treatment of weakened patients that require total skin electron irradiation. METHODS: This technique is a modification of a previously published reclined technique differing in that all six patient positions are treated with the gantry angled 60° from vertically down. The patient is located at a treatment distance of 330 cm SSD along the CA of the beam. The 3/8' thick Lexan beam spoiler is placed 25 cm from the most proximal surface of the patient for all patient treatment positions...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047400/su-f-t-70-a-high-dose-rate-total-skin-electron-irradiation-technique-with-a-specific-inter-film-variation-correction-method-for-very-large-electron-beam-fields
#20
X Yang, J Rosenfield, X Dong, E Elder, A Dhabaan
PURPOSE: Rotational total skin electron irradiation (RTSEI) is used in the treatment of cutaneous T-cell lymphoma. Due to inter-film uniformity variations the dosimetry measurement of a large electron beam of a very low energy is challenging. This work provides a method to improve the accuracy of flatness and symmetry for a very large treatment field of low electron energy used in dual beam RTSEI. METHODS: RTSEI is delivered by dual angles field a gantry of ±20 degrees of 270 to cover the upper and the lower halves of the patient body with acceptable beam uniformity...
June 2016: Medical Physics
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