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https://www.readbyqxmd.com/read/29793053/aggressive-fluid-and-sodium-restriction-in-decompensated-heart-failure-with-preserved-ejection-fraction-results-from-a-randomized-clinical-trial
#1
Karina Sanches Machado d'Almeida, Eneida Rejane Rabelo-Silva, Gabriela Corrêa Souza, Melina Maria Trojahn, Sofia Louise Santin Barilli, Graziella Aliti, Luís Eduardo Rohde, Andreia Biolo, Luís Beck-da-Silva
OBJECTIVES: Sodium and fluid restriction is commonly prescribed for heart failure patients. However, its role in the treatment of heart failure with preserved ejection fraction (HFpEF) remains unclear. The aim of this study was to compare the effect of a diet with sodium and fluid restriction with an unrestricted diet in patients admitted for decompensated HFpEF. METHODS: Patients were randomized to a diet with sodium (0.8 g/d) and fluid (800 mL/d) restriction (intervention group [IG]) or an unrestricted diet (control group [CG]) and followed for 7 d or hospital discharge...
March 21, 2018: Nutrition
https://www.readbyqxmd.com/read/29780941/unilateral-paraneoplastic-optic-disc-edema-and-retinal-periphlebitis-in-pineal-germinoma
#2
Gunay Uludag, Aslihan Onay, Sumru Onal
Purpose: To describe a unilateral ocular paraneoplastic syndrome in pineal germinoma. Observations: A 24-year-old male presented with diplopia, excessive thirst, and frequent urination. Cranial MRI showed a mass in pineal gland. Dorsal midbrain syndrome signs were present. Examination showed optic disc edema and segmental retinal periphlebitis in right and normal fundus in left eye. Rheumatologic work-up was negative. Brain biopsy confirmed pineal germinoma. Retinal findings were attributed to paraneoplastic syndrome...
June 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29780140/fulminant-type-1-diabetes-mellitus-presenting-15-days-after-delivery-diagnosed-in-cooperation-with-obstetricians
#3
Junji Sagawa, Yoko Yoshii, Mitsunobu Kubota
The patient was a 32-year-old Japanese woman who was given a 75-g oral glucose tolerance test at the 35th week of pregnancy and was normoglycemic. She had excessive thirst and polyuria from 15 days after delivery. When she visited for the 1-month postpartum checkup, her plasma glucose level was 479 mg/dL, HbA1c was 7.4%, and urinary C-peptide was 1.1 μg/mL; she was therefore diagnosed with fulminant type 1 diabetes mellitus associated with pregnancy. All physicians should be aware of this disease so as to provide a prompt diagnosis and emergency treatment and consequently improve the maternal prognosis...
May 18, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29774002/on-the-drive-specificity-of-freudian-drives-for-the-generation-of-seeking-activities-the-importance-of-the-underestimated-imperative-motor-factor
#4
Michael Kirsch, Wolfgang Mertens
Doubters of Freud's theory of drives frequently mentioned that his approach is outdated and therefore cannot be useful for solving current problems in patients with mental disorders. At present, many scientists believe that affects rather than drives are of utmost importance for the emotional life and the theoretical framework of affective neuroscience, developed by Panksepp, strongly underpinned this view. Panksepp evaluated seven so-called command systems and the SEEKING system is therein of central importance...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29770221/risperidone-induced-type-2-diabetes-presenting-with-diabetic-ketoacidosis
#5
Clarissa Ern Hui Fang, Mohammed Faraz Rafey, Aine Cunningham, Sean F Dinneen, Francis M Finucane
A 28-year-old male presented with 2 days of vomiting and abdominal pain, preceded by 2 weeks of thirst, polyuria and polydipsia. He had recently started risperidone for obsessive-compulsive disorder. He reported a high dietary sugar intake and had a strong family history of type 2 diabetes mellitus (T2DM). On admission, he was tachycardic, tachypnoeic and drowsy with a Glasgow Coma Scale (GCS) of 10/15. We noted axillary acanthosis nigricans and obesity (BMI 33.2 kg/m2 ). Dipstick urinalysis showed ketonuria and glycosuria...
2018: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29762074/use-of-artificial-hydration-at-the-end-of-life-a-survey-of-australian-and-new-zealand-palliative-medicine-doctors
#6
Jacqueline Oehme, Caitlin Sheehan
BACKGROUND: Dying is ubiquitous, yet the optimal management of hydration in the terminal phase is undetermined. Palliative care (PC) doctors' practices may act as a de facto measure of the benefits and burdens of artificial hydration (AH) use. OBJECTIVE: To identify PC doctors' AH prescribing practices for imminently dying patients and possible influencing factors. METHODS: An online survey of doctors belonging to the Australian and New Zealand Society of Palliative Medicine...
May 15, 2018: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/29761479/antidepressants-for-insomnia-in-adults
#7
REVIEW
Hazel Everitt, David S Baldwin, Beth Stuart, Gosia Lipinska, Andrew Mayers, Andrea L Malizia, Christopher Cf Manson, Sue Wilson
BACKGROUND: Insomnia disorder is a subjective condition of unsatisfactory sleep (e.g. sleep onset, maintenance, early waking, impairment of daytime functioning). Insomnia disorder impairs quality of life and is associated with an increased risk of physical and mental health problems including anxiety, depression, drug and alcohol abuse, and increased health service use. hypnotic medications (e.g. benzodiazepines and 'Z' drugs) are licensed for sleep promotion, but can induce tolerance and dependence, although many people remain on long-term treatment...
May 14, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29756097/evaluation-of-stressors-in-intensive-care-units
#8
Yücel Gültekin, Zerrin Özçelik, Seda Banu Akıncı, Halil Kaya Yorgancı
Objective: Physical and psychological stressors adversely affect the treatment and length of stay of patients in intensive care units. In this study, we aimed to describe environmental and psychological stressors affecting intensive care unit patients and to determine their priorities. Material and Methods: In this study, the 40-item Intensive Care Unit Environmental Stressor Scale was administered to patients in the General Surgery Intensive Care Unit and the Anesthesiology and Reanimation Intensive Care Unit...
2018: Turkish Journal of Surgery
https://www.readbyqxmd.com/read/29710346/use-of-textured-thin-liquids-in-patients-with-dysphagia
#9
Melissa M Howard, Paul M Nissenson, Lauren Meeks, Emily R Rosario
Purpose: The goals of this article are to explore the use of textured thin liquids for dysphagic patients who require thickened liquids and to illustrate their impact on hydration and patient satisfaction. Method: A retrospective evaluation of textured thin liquids was completed using patient data looking at laboratory values relevant to the detection of dehydration (blood urea nitrogen, creatinine, sodium) and patient satisfaction (using a clinician-generated questionnaire) on different modified liquid textures...
April 18, 2018: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/29707541/personalized-hydration-strategy-attenuates-the-rise-in-heart-rate-and-in-skin-temperature-without-altering-cycling-capacity-in-the-heat
#10
Denise de Melo-Marins, Ana Angélica Souza-Silva, Gabriel Lucas Leite da Silva-Santos, Francisco de Assis Freire-Júnior, Jason Kai Wei Lee, Orlando Laitano
The optimal hydration plan [i.e., drink to thirst, ad libitum (ADL), or personalized plan] to be adopted during exercise in recreational athletes has recently been a matter of debate and, due to conflicting results, consensus does not exist. In the present investigation, we tested whether a personalized hydration strategy based on sweat rate would affect cardiovascular and thermoregulatory responses and exercise capacity in the heat. Eleven recreational male cyclists underwent two familiarization cycling sessions in the heat (34°C, 40% RH) where sweat rate was also determined...
2018: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29704610/thirst-dependent-activity-of-the-insular-cortex-reflects-its-emotion-related-subdivision-a-cerebral-blood-flow-study
#11
Lea Meier, Andrea Federspiel, Kay Jann, Roland Wiest, Werner Strik, Thomas Dierks
Recent studies investigating neural correlates of human thirst have identified various subcortical and telencephalic brain areas. The experience of thirst represents a homeostatic emotion and a state that slowly evolves over time. Therefore, the present study aims at systematically examining cerebral perfusion during the parametric progression of thirst. We measured subjective thirst ratings, serum parameters and cerebral blood flow in 20 healthy subjects across four different thirst stages: intense thirst, moderate thirst, subjective satiation and physiological satiation...
April 25, 2018: Neuroscience
https://www.readbyqxmd.com/read/29700894/consensus-statement-on-clear-fluids-fasting-for-elective-pediatirc-general-anesthesia
#12
Mark Thomas, Christa Morrison, Richard Newton, Ehrenfried Schindler
Pediatric anesthetic guidelines for the management of preoperative fasting of clear fluids are currently 2 hours. The traditional 2 hours clear fluid fasting time was recommended to decrease the risk of pulmonary aspiration and is not in keeping with current literature. It appears that a liberalized clear fluid fasting regime does not affect the incidence of pulmonary aspiration and in those who do aspirate, the sequelae are not usually severe or long-lasting. With a 2-hour clear fasting policy, the literature suggests that this translates into 6-7 hours actual duration of fasting with several studies up to 15 hours...
April 27, 2018: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/29691160/the-frustrating-attempt-to-limit-the-interdialytic-weight-gain-in-patients-on-chronic-hemodialysis-new-insights-into-an-old-problem
#13
REVIEW
Maurizio Bossola, Gilda Pepe, Carlo Vulpio
A significant percentage of patients on chronic hemodialysis have an interdialytic weight gain (IDWG) above the recommended values. High IDWG has detrimental effects on survival, cardiovascular outcomes, and quality of life. High IDWG is secondary to poor adherence to fluid restriction and to excessive intake of fluids, due to thirst and xerostomia. Various strategies have been proposed to limit IDWG such as the reduction of dietary salt intake, behavioral interventions aimed at improving the adherence to fluid restriction, the improvement of xerostomia, and the use of lower dialysate sodium concentration...
April 21, 2018: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/29689036/-palliative-care-and-heart-failure-is-it-time-to-talk
#14
Massimo Romanò
Heart failure (HF) is one of the leading causes of hospitalization in high-income countries and has a profound negative impact on quality of life. In the United States there are more than 900,000 new cases per year and over one million hospital admissions with a primary diagnosis of HF. A prevalence of 6,500,000 cases (2.2% of the population of aged >20 years) was estimated for the US in 2014, in which there were 300,000 related deaths. Although survival has increased, thanks to the pharmacological and non pharmacological therapy, roughly 50% of HF patients die within 5 years of being diagnosed...
April 2018: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/29685363/fulminant-type-1-diabetes-mellitus-with-remarkable-elevation-of-serum-pancreatic-enzymes
#15
Mikio Nakajima, Masamitsu Shirokawa, Tomotsugu Nakano, Hideaki Goto
Fulminant type 1 diabetes mellitus progresses extremely rapidly and is accompanied by ketoacidosis. Patients with the disease present at emergency departments with non-specific symptoms, including fever, nausea, vomiting, and abdominal pain. Here, we present a case of fulminant type 1 diabetes mellitus where the patient was initially misdiagnosed with gastroenteritis and acute pancreatitis. A 50-year-old Japanese woman was referred to our hospital with coma and shock. She had presented with nausea, vomiting, abdominal pain and thirst from 5 days before admission, and had been misdiagnosed with gastroenteritis by her primary care physician...
April 14, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29684984/effects-of-preoperative-oral-carbohydrate-administration-on-patient-well-being-and-satisfaction-in-thyroid-surgery
#16
A Ram Doo, Hyunsup Hwang, Min-Jong Ki, Jun-Rae Lee, Dong-Chan Kim
Background: Although the positive effects of preoperative oral carbohydrate administration on clinical outcomes following major surgery have been reported continuously, there are few investigations of them in minor surgical patients. The present study was designed to examine the effects of preoperative oral carbohydrate administration on patient well-being and satisfaction in patients undergoing thyroidectomy. Methods: Fifty adults aged 20-65 years and scheduled for elective thyroidectomy in first schedule in the morning were allocated to one of two groups...
April 24, 2018: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/29681971/analysis-of-dietary-related-factors-of-recurrent-aphthous-stomatitis-among-college-students
#17
Qian Du, Shenglou Ni, Yanling Fu, Sanhai Liu
Objective: We investigated the occurrence of recurrent aphthous stomatitis (RAS) among college students and its potential influence by dietary habits. Methods: Study of dietary habits and RAS among students in Beijing University of Chinese Medicine was carried by homemade questionnaire. Multivariate binary logistic regression analysis was used to identify RAS risk factors and explore their relations. Results: Among 1011 investigated college students, family history (odds ratio (OR) 1...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29678523/safety-and-efficacy-of-mesenchymal-stem-cells-for-radiation-induced-xerostomia-a-randomized-placebo-controlled-phase-1-2-trial-mesrix
#18
Christian Grønhøj, David H Jensen, Peter Vester-Glowinski, Siri Beier Jensen, Allan Bardow, Roberto S Oliveri, Lea Munthe Fog, Lena Specht, Carsten Thomsen, Sune Darkner, Michael Jensen, Vera Müller, Katalin Kiss, Tina Agander, Elo Andersen, Anne Fischer-Nielsen, Christian von Buchwald
BACKGROUND: Salivary gland hypofunction and xerostomia are major complications to head and neck radiotherapy. This trial assessed the safety and efficacy of adipose tissue-derived mesenchymal stem cell (ASC) therapy for radiation-induced xerostomia. PATIENT AND METHODS: This randomized, placebo-controlled phase 1/2 trial included 30 patients, randomized in a 1:1 ratio to receive ultrasound-guided transplantation of ASCs or placebo to the submandibular glands. Patients had previously received radiotherapy for a T1-2, N0-2A, human papillomavirus-positive, oropharyngeal squamous cell carcinoma...
March 6, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29662841/effect-of-mixed-fruit-and-vegetable-juice-on-alcohol-hangovers-in-healthy-adults
#19
Min-Ju Kim, Sang-Wook Lim, Jong-Hyun Kim, Da-Jeong Choe, Jung-In Kim, Min-Jung Kang
The purpose of this study was to investigate the effects of mixed fruit and vegetable juice on alcohol hangover in healthy adults in a randomized crossover trial. Angelica keiskei /green grape/pear juice (AGP juice) was a mixture of A. keiskei juice, green grape juice, and pear juice at 1:1:1 ratio. Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) activities of AGP juice were measured in vitro . Fifteen healthy adults consumed alcohol (1.25 g/kg weight), and either water (control group) or AGP juice (AGP juice group)...
March 2018: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/29656590/-got-rats-global-environmental-costs-of-thirst-for-milk-include-acute-biodiversity-impacts-linked-to-dairy-feed-production
#20
Juan J Luque-Larena, François Mougeot, Beatriz Arroyo, Xavier Lambin
Bai et al. (2018) determined that China's increasing milk demand is expected to raise global greenhouse gas (GHG) emissions by 35%, expand dairy land by 32% and lift nitrogen pollution by 48%. Producing the additional milk in China adds to the environmental cost of animal feed transfers (from 1 to 6.2 Tg of alfalfa), while importing the extra milk would disproportionately transfer environmental burdens to exporting nations. Bai et al. (2018) conclude that the more sustainable future for milk-thirsty regions will rely on improving domestic milk and feed production efficiencies up to the level of major milk exporters such as the European Union (EU), the current leading region in milk production (USDA, 2017)...
April 14, 2018: Global Change Biology
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