keyword
MENU ▼
Read by QxMD icon Read
search

Thirst

keyword
https://www.readbyqxmd.com/read/29140262/influence-of-professional-affiliation-on-expert-s-view-on-welfare-measures
#1
Nina Dam Otten, Tine Rousing, Björn Forkman
The present study seeks to investigate the influence of expert affiliation in the weighing procedures within animal welfare assessments. Experts are often gathered with different backgrounds with differing approaches to animal welfare posing a potential pitfall if affiliation groups are not balanced in numbers of experts. At two time points (2012 and 2016), dairy cattle and swine experts from four different stakeholder groups, namely researchers (RES), production advisors (CONS), practicing veterinarians (VET) and animal welfare control officers (AWC) were asked to weigh eight different welfare criteria: Hunger, Thirst, Resting comfort, Ease of movement, Injuries, Disease, Human-animal bond and Emotional state...
November 15, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/29129925/the-neural-basis-of-homeostatic-and-anticipatory-thirst
#2
REVIEW
Claire Gizowski, Charles W Bourque
Water intake is one of the most basic physiological responses and is essential to sustain life. The perception of thirst has a critical role in controlling body fluid homeostasis and if neglected or dysregulated can lead to life-threatening pathologies. Clear evidence suggests that the perception of thirst occurs in higher-order centres, such as the anterior cingulate cortex (ACC) and insular cortex (IC), which receive information from midline thalamic relay nuclei. Multiple brain regions, notably circumventricular organs such as the organum vasculosum lamina terminalis (OVLT) and subfornical organ (SFO), monitor changes in blood osmolality, solute load and hormone circulation and are thought to orchestrate appropriate responses to maintain extracellular fluid near ideal set points by engaging the medial thalamic-ACC/IC network...
November 13, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29125018/the-glasgow-antipsychotic-side-effects-scale-for-clozapine-in-inpatients-and-outpatients-with-schizophrenia-or-schizoaffective-disorder
#3
Dragana Ignjatović Ristić, Dan Cohen, Andrea Obradović, Katarina Nikić-Đuričić, Marija Drašković, Darko Hinić
BACKGROUND: The inconsistency in clinician and patient ratings of clozapine-induced side effects underscore the need to supplement clinician-based estimates of side effects with patient-reported ones. AIMS: The main aims of the study are validation of the Glasgow antipsychotic side-effects scale for clozapine (GASS-C) in Serbian inpatients/outpatients with schizophrenia or schizo-affective disorder and recommendations for its future use, based on common and rare clozapine-associated side-effects...
November 10, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/29123425/long-term-safety-profile-of-tolvaptan-in-autosomal-dominant-polycystic-kidney-disease-patients-tempo-extension-japan-trial
#4
Satoru Muto, Tadashi Okada, Moriyoshi Yasuda, Hidetsugu Tsubouchi, Koji Nakajima, Shigeo Horie
Aim: The aim of this trial (ClinicalTrials.gov identifier: NCT01280721) was to investigate the long-term safety profile of tolvaptan in Japanese patients with autosomal dominant polycystic kidney disease (ADPKD). Methods: This open-label multicenter trial was conducted to examine adverse drug reactions (ADRs) related to tolvaptan up to an additional 3 years in 135 Japanese patients who participated in the Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and its Outcomes (TEMPO) 3:4 trial at doses of 60-120 mg/d...
2017: Drug, Healthcare and Patient Safety
https://www.readbyqxmd.com/read/29122962/frequent-drinking-of-small-volumes-improves-cardiac-function-and-survival-in-rats-with-chronic-heart-failure
#5
Can Zheng, Meihua Li, Toru Kawada, Masashi Inagaki, Kazunori Uemura, Masaru Sugimachi
Fluid retention is the main reason for the high hospitalization rate among patients with chronic heart failure (CHF). Given the lack of knowledge about fluid intake regulation and its consequences in patients with CHF, current guidelines do not provide clear direction for fluid management. Using a rat model of CHF, we investigated altering drinking behaviors and explored fluid management strategies. CHF was induced by ligating the left anterior descending coronary arteries in 8-week-old, male, Sprague-Dawley rats...
November 2017: Physiological Reports
https://www.readbyqxmd.com/read/29120013/primary-polydipsia-in-the-medical-and-psychiatric-patient-characteristics-complications-and-therapy
#6
Clara Sailer, Bettina Winzeler, Mirjam Christ-Crain
Primary polydipsia (PP) has been defined as excessive intake of fluids. However, the pathogenesis of PP remains unexplored. Different theories include a dysfunction in the thirst mechanism, involvement of the hippocampus, stress-reducing behaviour and lesion occurrences in specific areas of the brain. Most studies have been performed in the psychiatric setting, indicating that PP coincides with schizophrenia, anxiety disorder and depression. However, an increasing number of case reports emphasise the incidence of PP in non-psychiatric patients...
November 9, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29112626/effects-of-ad-libitum-low-carbohydrate-high-fat-dieting-in-middle-age-male-runners
#7
Alexander J Heatherly, Lauren G Killen, Ashton F Smith, Hunter S Waldman, Angela Hollingsworth, Christie L Seltmann, Eric K O'Neal
PURPOSE: This study examined the effects of a 3-week ad libitum high fat (~70% of calories), low carbohydrate (<50 g/day) diet (LCHF) on markers of endurance performance in middle-aged, recreationally competitive male runners. METHODS: All subjects (n = 8) following their normal HC diet had anthropometric measures assessed and completed 5, 10-min running bouts at multiple individual race paces in the heat while physiological, metabolic variables and perceptual responses were recorded...
November 6, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29108316/ultrasound-guided-percutaneous-microwave-ablation-of-benign-breast-lesions
#8
Jie Yu, Bao-Hua Chen, Jing Zhang, Zhi-Yu Han, Han Wu, Yan Huang, Meng-Juan Mu, Ping Liang
The benign breast lesions (BBLs) share a high incidence for women and therapy methods with minimal invasion and better cosmetic outcome are thirsted for. In this study, 122 patients with 198 biopsy-proved BBLs were enrolled. Ultrasound (US)-guided microwave ablation (MWA) was performed with local anesthesia from November, 2013 to April, 2016. The mean longest tumor size assessed was 1.6±0.7 cm (ranging 0.7-4.9 cm). MWA was successfully performed in all cases including 85 lesions adjacent to the skin, pectoralis and areola...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29101501/severe-hypernatraemic-dehydration-and-unconsciousness-in-a-care-dependent-inpatient-treated-with-empagliflozin
#9
Georg Gelbenegger, Nina Buchtele, Christian Schoergenhofer, Martin Roeggla, Michael Schwameis
A 66-year-old Caucasian male became unconscious 2 weeks after initiation of add-on therapy with empagliflozin for poorly controlled type 2 diabetes mellitus. The inpatient had recently suffered focal pontine stroke, rendering him bedridden and requiring increased nursing care, including assistance with drinking. The patient had received empagliflozin 10 mg once daily for glycaemic control. Investigations revealed hypernatraemia (164 mmol/l), a urine glucose level of 3935 mg/dl, and a creatinine level of 2...
November 3, 2017: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/29077558/-the-genetics-of-obesity-pathogenetic-clinical-and-diagnostic-aspects
#10
Artur Barczyk, Anna Kutkowska-Kaźmierczak, Jennifer Castañeda, Ewa Obersztyn
Due to its prevalence and its health-related, economic and social consequences, childhood and adult obesity is a complex, medical and civilizational problem, which has been on the increase in the last decade. The results of multi-center investigations reveal that genetic factors play an essential role in the etiopathogenesis of obesity, particularly in the case of extreme cases with very early onset. The Body Mass Index (BMI) is one of the most frequently used indicators of obesity and shows a strong genetic component with a 40-70% degree of heritability...
2017: Developmental Period Medicine
https://www.readbyqxmd.com/read/29075986/a-practical-method-for-prevention-of-readmission-for-symptomatic-hyponatremia-following-transsphenoidal-surgery
#11
William T Burke, David J Cote, Sherry I Iuliano, Hasan A Zaidi, Edward R Laws
INTRODUCTION: Patients undergoing transsphenoidal pituitary surgery (TSS) are at risk for several serious complications, including the syndrome of inappropriate antidiuretic hormone and subsequent hyponatremia. OBJECTIVE: In this study, we examined the effect of 1 week of post-discharge fluid restriction to 1.0 L daily on rates of post-operative readmission for hyponatremia. METHODS: We retrospectively analyzed all patients undergoing TSS from 2008 to 2014 and prospectively recorded patient data from 2015 to 2017...
October 26, 2017: Pituitary
https://www.readbyqxmd.com/read/29073185/exploring-the-perceptions-of-physicians-caregivers-and-families-towards-artificial-nutrition-and-hydration-for-people-in-permanent-vegetative-state-how-can-a-photo-elicitation-method-help
#12
Elodie Cretin, Lionel Pazart, Marie-Christine Rousseau, Alain Noé, Pierre Decavel, Aline Chassagne, Aurélie Godard-Marceau, Hélène Trimaille, Florence Mathieu-Nicot, Yvan Beaussant, Damien Gabriel, Serge Daneault, Régis Aubry
The question of withdrawing artificial nutrition and hydration from people in a permanent vegetative state sparks considerable ethical and legal debate. Therefore, understanding the elements that influence such a decision is crucial. However, exploring perceptions of artificial nutrition and hydration is methodologically challenging for several reasons. First, because of the emotional state of the professionals and family members, who are facing an extremely distressing situation; second, because this question mirrors representations linked to a deep-rooted fear of dying of hunger and thirst; and third, because of taboos surrounding death...
2017: PloS One
https://www.readbyqxmd.com/read/29038723/survey-of-awareness-of-diabetes-mellitus-among-the-arar-population-northern-border-region-of-saudi-arabia
#13
Aseel Menwer Alanazi, Nagah Mohamed Abo El-Fetoh, Hanan Khalid Alotaibi, Khalid Ayed Alanazi, Banan Khalid Alotaibi, Sultan Majed Alshammari, Saud Rteamy Alanazi, Meshari Dalaf Alhazmi, Yousef Talal Alshammari, Zaid Qati Alshammari
BACKGROUND: Diabetes Mellitus (DM) is one of the most widely prevalent diseases in Saudi Arabia. Health education is considered an essential component to improve knowledge and change behavior. People affected by diabetes often have inadequate knowledge about the nature of diabetes, its risk factors and associated complication. OBJECTIVES: The aim of this study was to assess the awareness of the Arar population with various aspects of diabetes mellitus. METHODS: A cross-sectional study was carried out in Arar city, the capital of the Northern Province of Kingdom of Saudi Arabia (KSA)...
September 2017: Electronic Physician
https://www.readbyqxmd.com/read/29035599/progressive-dehydration-in-junior-laser-class-sailors-during-world-championship
#14
Giannis Arnaoutis, Panagiotis Verginadis, Adam D Seal, Ioannis Vogiatzis, Labros S Sidossis, Stavros A Kavouras
The purpose of this manuscript is to assess hydration status of elite young sailing athletes during World Championship competition. 12 young elite male Laser Class sailors (age: 15.8±1.1 y, height: 1.74±0.1 m, weight: 65.1±1.5 kg, body fat: 12.5±3.1%, training experience: 7.0±1.2 y) participated in this descriptive study. After three-day baseline bodyweight measurements, hydration status was assessed via pre- and post-race body weights, urine specific gravity, and thirst ratings via a visual analog scale during 4 consecutive days of racing...
October 16, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29031578/short-term-exposure-to-bisphenol-a-affects-water-and-salt-intakes-differently-in-male-and-ovariectomised-female-rats
#15
Paula Nuñez, Juan Arguelles, Carmen Perillan
Thirst and sodium appetite are motivational states that lead to the search for and ingestion of water and sodium, thus contributing to maintenance of hydromineral balance. Oestrogens affect fluid intake and sodium preference. Bisphenol A (BPA) is an environmental endocrine-disrupting substance with oestrogenic activity. Whether there are sex differences in the ingestive effects of BPA is unknown. Therefore, the aim of the present work was to determine the effect of short-term treatment of low doses of BPA on thirst and sodium appetite in adult male and ovariectomised Wistar rats...
January 1, 2018: Appetite
https://www.readbyqxmd.com/read/29026268/characteristic-clinical-features-of-adipsic-hypernatremia-patients-with-subfornical-organ-targeting-antibody
#16
Akari Nakamura-Utsunomiya, Takeshi Y Hiyama, Satoshi Okada, Masaharu Noda, Masao Kobayashi
Adipsic hypernatremia is a rare disease presenting as persistent hypernatremia with disturbance of thirst regulation and hypothalamic dysfunction. As a result of congenital disease, tumors, or inflammation, most cases are accompanied by structural abnormalities in the hypothalamic-pituitary area. While cases with no hypothalamic-pituitary structural lesion have been reported, their etiology has not been elucidated. Recently, we reported three patients with adipsic hypernatremia whose serum-derived immunoglobulin (Ig) specifically reacted with mouse subfornical organ (SFO) tissue...
2017: Clinical Pediatric Endocrinology: Case Reports and Clinical Investigations: Official Journal of the Japanese Society for Pediatric Endocrinology
https://www.readbyqxmd.com/read/29025285/safety-and-efficacy-of-canagliflozin-in-elderly-patients-with-type-2-diabetes-mellitus-a-1-year-post-marketing-surveillance-in-japan
#17
Maki Goda, Tomoko Yamakura, Kazuyo Sasaki, Takumi Tajima, Makoto Ueno
Objective To evaluate the safety and efficacy of canagliflozin in elderly patients with type 2 diabetes mellitus (T2DM) in clinical settings. Methods We conducted a 1-year post-marketing surveillance (PMS) of canagliflozin in almost all the elderly patients (≥65 years old) with T2DM who began taking canagliflozin during the first 3 months after its launch in Japan. The main outcomes included the incidences of adverse drug reactions (ADRs), serious ADRs and the changes of laboratory tests as well as efficacy variables...
October 13, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28986397/potential-mechanisms-of-hypothalamic-renin-angiotensin-system-activation-by-leptin-and-doca-salt-for-the-control-of-resting-metabolism
#18
Sarah A Sapouckey, Guorui Deng, Curt D Sigmund, Justin L Grobe
The renin-angiotensin system (RAS), originally described as a circulating hormone system, is an enzymatic cascade in which the final vasoactive peptide angiotensin II (ANG) regulates cardiovascular, hydromineral, and metabolic functions. The RAS is also synthesized locally in a number of tissues including the brain, where it can act in a paracrine fashion to regulate blood pressure, thirst, fluid balance, and resting energy expenditure / resting metabolic rate (RMR). Recent studies demonstrate that ANG AT1A receptors (Agtr1a) specifically in agouti-related peptide (AgRP) neurons of the arcuate nucleus (ARC) coordinate autonomic and energy expenditure responses to various stimuli including deoxycorticosterone acetate (DOCA)-salt, high fat feeding, and leptin...
October 6, 2017: Physiological Genomics
https://www.readbyqxmd.com/read/28981824/thirst-increases-chorda-tympani-responses-to-sodium-chloride
#19
Thomas G Mast, Joseph M Breza, Robert J Contreras
In nature, water is present as a low-salt solution, thus we hypothesized that thirst would increase taste responses to low-salt solutions. We investigated the effect of thirst on the 2 different salt detection mechanisms present in the rat chorda tympani (CT) nerve. The first mechanism is dependent upon the epithelial sodium channel (ENaC), is blocked by benzamil, and is specific to the cation sodium. The second mechanism, while undefined, is independent of ENaC, and detects multiple cations. We expected thirst to increase benzamil-sensitive sodium responses due to mechanistically increasing the benzamil-sensitive ENaC...
October 1, 2017: Chemical Senses
https://www.readbyqxmd.com/read/28967192/the-polyuria-polydipsia-syndrome-a-diagnostic-challenge
#20
REVIEW
Nicole Nigro, Mathis Grossmann, Cherie Chiang, Warrick J Inder
The main determinants for the maintenance of water homeostasis are the hormone arginine-vasopressin (AVP) and thirst. Disturbances in these regulatory mechanisms can lead to the polyuria-polydipsia syndrome, which comprises of three different conditions: central diabetes insipidus (DI) due to insufficient secretion of AVP, nephrogenic DI caused by renal insensitivity to AVP action, and primary polydipsia due to excessive fluid intake and consequent physiologic suppression of AVP. It is crucial to determine the exact diagnosis because treatment strategies vary substantially...
October 2, 2017: Internal Medicine Journal
keyword
keyword
61625
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"