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https://www.readbyqxmd.com/read/29218673/results-of-endoscopic-vacuum-assisted-closure-device-for-treatment-of-upper-gi-leaks
#1
Marc Bludau, Hans F Fuchs, Till Herbold, Martin K H Maus, Hakan Alakus, Felix Popp, Jessica M Leers, Christiane J Bruns, Arnulf H Hölscher, Wolfgang Schröder, Seung-Hun Chon
BACKGROUND: Esophageal perforations and postoperative leakage of esophagogastrostomies are considered to be life-threatening conditions due to the potential development of mediastinitis and consecutive sepsis. Vacuum-assisted closure (VAC) techniques, a well-established treatment method for superficial infected wounds, are based on a negative pressure applied to the wound via a vacuum-sealed sponge. Endoluminal VAC (E-VAC) therapy as a treatment for GI leakages in the rectum was introduced in 2008...
December 7, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29216669/-it-is-up-to-you-a-qualitative-study-of-inequalities-in-healthcare-from-the-patient-s-perspective
#2
Sara Lena Schröder, Olaf Martin, Martin Mlinarić, Matthias Richter
Objective The aim of this qualitative study was to explore inequalities in healthcare from the patient's perspective. Methods 44 semi-structured interviews with patients, aged 59-80 years, were conducted at the university hospital in Halle, Germany in 2014 and 2015. We analyzed the narratives following inductive qualitative content analysis. Results Most of the patients (82%) perceived inequalities in healthcare. Dimensions of healthcare inequalities from the patient's perspective were regional differences, type of health insurance, quality of physicians and the patients themselves (Income, Age)...
December 7, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29215017/active-site-plasticity-revealed-in-the-asymmetric-dimer-of-anprx6-the-1-cys-peroxiredoxin-and-molecular-chaperone-from-anabaena-sp-pcc-7210
#3
Yogesh Mishra, Michael Hall, Roland Locmelis, Kwangho Nam, Christopher A G Söderberg, Patrik Storm, Neha Chaurasia, Lal Chand Rai, Stefan Jansson, Wolfgang P Schröder, Uwe H Sauer
Peroxiredoxins (Prxs) are vital regulators of intracellular reactive oxygen species levels in all living organisms. Their activity depends on one or two catalytically active cysteine residues, the peroxidatic Cys (CP) and, if present, the resolving Cys (CR). A detailed catalytic cycle has been derived for typical 2-Cys Prxs, however, little is known about the catalytic cycle of 1-Cys Prxs. We have characterized Prx6 from the cyanobacterium Anabaena sp. strain PCC7120 (AnPrx6) and found that in addition to the expected peroxidase activity, AnPrx6 can act as a molecular chaperone in its dimeric state, contrary to other Prxs...
December 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29214862/screening-for-problematic-worry-in-adults-with-a-single-item-from-the-penn-state-worry-questionnaire
#4
Hans S Schroder, D Angus Clark, Jason S Moser
As the rapid assessment of mental health is a growing need, a quick and valid tool for the early detection of symptoms that can be flexibly deployed across a range of contexts may be especially beneficial. This is particularly true of anxiety problems, which when undetected contribute to health care costs and lost work productivity. Data from more than 10,000 respondents (primarily female undergraduates) were used to test whether a single item from the popular Penn State Worry Questionnaire could serve as a screening tool in settings where administration of the full scale is undesirable...
February 1, 2017: Assessment
https://www.readbyqxmd.com/read/29207394/cumulative-effect-of-obesogenic-behaviours-on-adiposity-in-spanish-children-and-adolescents
#5
Helmut Schröder, Rowaedh Ahmed Bawaked, Lourdes Ribas-Barba, Maria Izquierdo-Pulido, Blanca Roman-Viñas, Montserrat Fíto, Lluis Serra-Majem
OBJECTIVE: Little is known about the cumulative effect of obesogenic behaviours on childhood obesity risk. We determined the cumulative effect on BMI z-score, waist-to-height ratio (WHtR), overweight and abdominal obesity of four lifestyle behaviours that have been linked to obesity. METHODS: In this cross-sectional analysis, data were obtained from the EnKid sudy, a representative sample of Spanish youth. The study included 1,614 boys and girls aged 5-18 years...
December 6, 2017: Obesity Facts
https://www.readbyqxmd.com/read/29204437/reference-values-of-flexion-and-supination-in-the-elbow-joint-of-a-cohort-without-shoulder-pathologies
#6
Mehmet F Güleçyüz, Matthias F Pietschmann, Stefan Michalski, Ferdinand M Eberhard, Alexander Crispin, Christian Schröder, Maximilian J Mittermüller, Peter E Müller
Background: After surgery of the long head of the biceps tendon, the examination of the biceps brachii muscle function and strength is common clinical practice. The muscle strength is usually compared with the uninjured contralateral side or with a matched pair group assuming that the uninjured side can be used as an appropriate reference. Hypothesis/Purpose: The purpose of this study was to define reference values of the supination and flexion strength in the elbow joint and to investigate the influence of the arm positions and various anthropometric factors...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29203381/accuracy-of-3-clinical-tests-to-diagnose-proximal-hamstrings-tears-with-and-without-sciatic-nerve-involvement-in-patients-with-posterior-hip-pain
#7
RobRoy L Martin, Ricardo Gonçalves Schröder, Juan Gomez-Hoyos, Anthony N Khoury, Ian James Palmer, Ryan P McGovern, Hal David Martin
PURPOSE: To determine the diagnostic accuracy of the active hamstring test at 30° (A-30) and 90° (A-90) of knee flexion, the long stride heel strike (LSHS) test, and combination of the 3 tests for individuals with hamstring tendon tears, with and without sciatic nerve involvement. METHODS: A retrospective review of 564 consecutive clinical records identified 42 subjects with a mean age of 50.31 ± 15 years who underwent a standard physical examination prior to magnetic resonance imaging (MRI) evaluation and diagnostic injection for posterior hip...
December 1, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29195164/elderly-migrants-in-outpatient-and-inpatient-care-services-in-baden-w%C3%A3-rttemberg-germany
#8
Magdalena Eva Kowoll, Inga Meyer-Kühling, Christina Degen, Saskia Gladis, Peter Zeier, Johannes Schröder
OBJECTIVE: Given the expected underrepresentation of elderly migrant populations in healthcare utilization we examined their proportion in nursing homes and care services for the elderly. We expected that cultural aspects were rarely addressed in the services´ concepts. METHODS: A questionnaire was administered to all care providers; 66.3% of 2724 in- and outpatient services in Baden-Württemberg, Germany participated. RESULTS: 78% of the services provided healthcare to migrants, who accounted for 14...
November 21, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29194819/optical-properties-and-sequence-information-of-tin-centered-conjugated-microporous-polymers
#9
Uwe Heiko Bunz, Andrea Uptmoor, Sven Elbert, Irene Wacker, Rasmus Schröder, Michael Masterlerz, Jan Freudenberg, Ruben Ilyas
We synthesized conjugated microporous polymers (CMPs) based on tetrakis(4-ethynylphenyl)stannane and diiodobenzene as tectons, employing Sonogashira couplings under different conditions. Through variation of the reaction conditions (catalysts, bases and solvents), appearance, surface area and emission properties of the formed CMPs were significantly altered. Wet-chemical, acid-mediated digestion and analysis of the resulting struts of these otherwise insoluble networks give insight into their molecular setup...
November 30, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29188420/a-lateral-retinacular-release-during-total-knee-arthroplasty%C3%A2-changes-femorotibial-kinematics-an-in-vitro-study
#10
Arnd Steinbrück, Christian Schröder, Matthias Woiczinski, Alexander Glogaza, Peter E Müller, Volkmar Jansson, Andreas Fottner
INTRODUCTION: Lateral retinacular release (LRR) is a common procedure during total knee arthroplasty (TKA), especially if patellar maltracking is observed intraoperatively. The impact of LRR on patellofemoral kinematics is well-examined, but the influence on femorotibial kinematics requires more elucidation. Therefore, the aim of this study was to evaluate the effects of LRR on femorotibial kinematics in vitro. MATERIALS AND METHODS: A fixed bearing TKA was implanted in six human knee specimens...
November 29, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29188301/organic-amendments-in-a-long-term-field-trial-consequences-for-the-bulk-soil-bacterial-community-as-revealed-by-network-analysis
#11
Christoph A O Schmid, Peter Schröder, Martin Armbruster, Michael Schloter
This study intended to elucidate the long-term effects of organic soil amendments on bacterial co-occurrence in bulk soil with and without addition of mineral fertiliser. Previous research mostly neglected the bacterial co-occurrence structure and focussed mainly on the parameters species diversity and abundance changes of species. Here we present a systematic comparison of two frequently used soil amendments, manure and straw, with regard to their impact on bacterial co-occurrence in a long-term field trial in Speyer, Germany...
November 29, 2017: Microbial Ecology
https://www.readbyqxmd.com/read/29188296/association-of-cerebral-amyloid-%C3%AE-aggregation-with-cognitive-functioning-in-persons-without-dementia
#12
Willemijn J Jansen, Rik Ossenkoppele, Betty M Tijms, Anne M Fagan, Oskar Hansson, William E Klunk, Wiesje M van der Flier, Victor L Villemagne, Giovanni B Frisoni, Adam S Fleisher, Alberto Lleó, Mark A Mintun, Anders Wallin, Sebastiaan Engelborghs, Duk L Na, Gäel Chételat, José Luis Molinuevo, Susan M Landau, Niklas Mattsson, Johannes Kornhuber, Osama Sabri, Christopher C Rowe, Lucilla Parnetti, Julius Popp, Tormod Fladby, William J Jagust, Pauline Aalten, Dong Young Lee, Rik Vandenberghe, Catarina Resende de Oliveira, Elisabeth Kapaki, Lutz Froelich, Adrian Ivanoiu, Tomasz Gabryelewicz, Marcel M Verbeek, Páscual Sanchez-Juan, Helmut Hildebrandt, Vincent Camus, Marzena Zboch, David J Brooks, Alexander Drzezga, Juha O Rinne, Andrew Newberg, Alexandre de Mendonça, Marie Sarazin, Gil D Rabinovici, Karine Madsen, Milica G Kramberger, Agneta Nordberg, Vincent Mok, Barbara Mroczko, David A Wolk, Philipp T Meyer, Magda Tsolaki, Philip Scheltens, Frans R J Verhey, Pieter Jelle Visser, Dag Aarsland, Daniel Alcolea, Myriam Alexander, Ina S Almdahl, Steven E Arnold, Inês Baldeiras, Henryk Barthel, Bart N M van Berckel, Kaj Blennow, Mark A van Buchem, Enrica Cavedo, Kewei Chen, Elena Chipi, Ann D Cohen, Stefan Förster, Juan Fortea, Kristian S Frederiksen, Yvonne Freund-Levi, Olymbia Gkatzima, Mark Forrest Gordon, Timo Grimmer, Harald Hampel, Lucrezia Hausner, Sabine Hellwig, Sanna-Kaisa Herukka, Peter Johannsen, Aleksandra Klimkowicz-Mrowiec, Sebastian Köhler, Norman Koglin, Koen van Laere, Mony de Leon, Viviana Lisetti, Wolfgang Maier, Jan Marcusson, Olga Meulenbroek, Hanne M Møllergård, John C Morris, Arto Nordlund, Gerald P Novak, George P Paraskevas, Gayan Perera, Oliver Peters, Inez H G B Ramakers, Lorena Rami, Eloy Rodríguez-Rodríguez, Catherine M Roe, Uros Rot, Eckart Rüther, Isabel Santana, Johannes Schröder, Sang W Seo, Hilkka Sorininen, Luiza Spiru, Erik Stomrud, Hanne Struyfs, Charlotte E Teunissen, Stephanie J B Vos, Linda J C van Waalwijk van Doorn, Gunhild Waldemar, Åsa K Wallin, Jens Wiltfang, Henrik Zetterberg
Importance: Cerebral amyloid-β aggregation is an early event in Alzheimer disease (AD). Understanding the association between amyloid aggregation and cognitive manifestation in persons without dementia is important for a better understanding of the course of AD and for the design of prevention trials. Objective: To investigate whether amyloid-β aggregation is associated with cognitive functioning in persons without dementia. Design, Setting, and Participants: This cross-sectional study included 2908 participants with normal cognition and 4133 with mild cognitive impairment (MCI) from 53 studies in the multicenter Amyloid Biomarker Study...
November 29, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/29186746/-interdisciplinary-acute-medical-rehabilitation-after-sepsis-a-retrospective-analysis
#13
Max Emanuel Liebl, Nancy Elmer, Christine Schwedtke, Isabelle Schröder, Anett Reißhauer
Background Surviving sepsis may have consequences of high impact for the patients' further life regarding functioning in mobility and activities of daily living, among other fields. Patients consecutively have a great need of rehabilitation interventions beginning with early mobilization in the Intensive Care Unit ICU. Acute medical rehabilitation is a concept of early rehabilitation still in the acute care hospital, normally beginning after a direct transferal from the ICU. Its aim is to improve the patients' functioning in mobility and activities of daily living (ADL) to enable further post-acute rehabilitation interventions...
November 29, 2017: Die Rehabilitation
https://www.readbyqxmd.com/read/29183814/sulfur-mustard-resistant-keratinocytes-obtained-elevated-glutathione-levels-and-other-changes-in-the-antioxidative-defense-mechanism
#14
Simone Rothmiller, Sarah Schröder, Romano Strobelt, Markus Wolf, Jin Wang, Xiqian Jiang, Franz Worek, Dirk Steinritz, Horst Thiermann, Annette Schmidt
BACKGROUND: Sulfur mustard (SM) is a potent blistering chemical warfare agent, which was first used in 1917. Despite the Chemical Weapons Convention, a use was recently reported in Syria in 2015. This emphasizes the importance to develop countermeasures against chemical warfare agents. Despite intensive research, there is still no antidote or prophylaxis available against SM. METHODS: The newly developed SM-resistant keratinocyte cell line HaCaT/SM was used to identify new target structures for drug development, particularly the adaptations in protective measures against oxidative stress...
November 25, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/29183042/expression-and-regulation-of-s100-fused-type-protein-hornerin-at-the-ocular-surface-and-lacrimal-apparatus
#15
Fabian Garreis, Janine Jahn, Katharina Wild, Daniel B Abrar, Martin Schicht, Jens-Michael Schröder, Friedrich Paulsen
Purpose: The S100 fused-type proteins hornerin (HRNR) and filaggrin-2 (FLG2) are members of the epidermal differentiation complex, which is involved in terminal differentiation of keratinocytes via cornification as well as maintenance of the epidermal antimicrobial barrier. We investigated the expression and possible regulation of HRNR and FLG2 at the ocular surface and in the lacrimal apparatus. Methods: Tissues of the lacrimal apparatus and ocular surface were analyzed systematically by means of RT-PCR, immunohistochemistry, and immuntransmission electron microscopy (iTEM) for their ability to express and produce HRNR and FLG2...
November 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29176812/generation-y-and-surgical-residency-passing-the-baton-or-the-end-of-the-world-as-we-know-it-results-from-a-survey-among-medical-students-in-germany
#16
Robert Kleinert, Claudia Fuchs, Vanessa Romotzky, Laura Knepper, Marie-Luise Wasilewski, Wolfgang Schröder, Christiane Bruns, Christiane Woopen, Jessica Leers
INTRODUCTION: The current student generation have their own expectations toward professional life and pay particular attention to their work-life balance. Less interest in work-intensive specialties leads to a shortage of skilled candidates especially in surgery. In order to motivate students into a surgical residency, new priorities become important. A deeper understanding of the underlying arguments and students' expectations towards a surgical training are necessary to counteract a future shortage of specialized surgeons...
2017: PloS One
https://www.readbyqxmd.com/read/29176684/acupuncture-analgesia-involves-modulation-of-pain-induced-gamma-oscillations-and-cortical-network-connectivity
#17
Michael Hauck, Sven Schröder, Gesa Meyer-Hamme, Jürgen Lorenz, Sunja Friedrichs, Guido Nolte, Christian Gerloff, Andreas K Engel
Recent studies support the view that cortical sensory, limbic and executive networks and the autonomic nervous system might interact in distinct manners under the influence of acupuncture to modulate pain. We performed a double-blind crossover design study to investigate subjective ratings, EEG and ECG following experimental laser pain under the influence of sham and verum acupuncture in 26 healthy volunteers. We analyzed neuronal oscillations and inter-regional coherence in the gamma band of 128-channel-EEG recordings as well as heart rate variability (HRV) on two experimental days...
November 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29175384/neuron-specific-enolase-and-s-100b-in-prolonged-targeted-temperature-management-after-cardiac-arrest-a-randomised-study
#18
Christophe Henri Valdemar Duez, Anders Morten Grejs, Anni Nørgaard Jeppesen, Anne Dilani Schrøder, Eldar Søreide, Jørgen Feldbæk Nielsen, Hans Kirkegaard
BACKGROUND: We aimed to investigate the impact of prolonged targeted temperature management (TTM) in cardiac arrest patients on release of serum levels of NSE and S-100b and their prognostic performances. METHODS: This is a substudy of the Targeted Temperature Management for 24 vs 48hours trial. NSE and S-100b levels were analysed retrospectively in serum samples collected upon admission, at 24, 48, and 72hours after reaching the target temperature of 33 ±1°C...
November 21, 2017: Resuscitation
https://www.readbyqxmd.com/read/29169929/compound-heterozygous-ryr1-mutations-in-a-preterm-with-arthrogryposis-multiplex-congenita-and-prenatal-cns-bleeding
#19
Florian Brackmann, Matthias Türk, Nils Gratzki, Oliver Rompel, Heinz Jungbluth, Rolf Schröder, Regina Trollmann
RYR1 mutations, the most common cause of non-dystrophic neuromuscular disorders, are associated with the malignant hyperthermia susceptibility (MHS) trait as well as congenital myopathies with widely variable clinical and histopathological manifestations. Recently, bleeding anomalies have been reported in association with certain RYR1 mutations. Here we report a preterm infant born at 32 weeks gestation with arthrogryposis multiplex congenita due to compound heterozygous, previously MHS-associated RYR1 mutations, with additional signs of prenatal hemorrhage...
September 28, 2017: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/29164092/the-nuisance-mosquito-anopheles-plumbeus-stephens-1828-in-germany-a-questionnaire-survey-may-help-support-surveillance-and-control
#20
Eva C Heym, Jette Schröder, Helge Kampen, Doreen Walther
The mosquito species Anopheles plumbeus is an aggressive biter and a potential vector of malaria parasites and West Nile virus. It occurs naturally at low population densities, as its larval development is adapted to the specific water qualities found in tree holes. However, probably owing to environmental changes, it has recently been observed in several European countries to use increasingly often artificial breeding habitats that may lead to mass development and severe annoyance to humans living close by...
2017: Frontiers in Public Health
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