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https://www.readbyqxmd.com/read/27921201/sensory-clusters-of-adults-with-and-without-autism-spectrum-conditions
#1
Marie Elwin, Agneta Schröder, Lena Ek, Tuula Wallsten, Lars Kjellin
We identified clusters of atypical sensory functioning adults with ASC by hierarchical cluster analysis. A new scale for commonly self-reported sensory reactivity was used as a measure. In a low frequency group (n = 37), all subscale scores were relatively low, in particular atypical sensory/motor reactivity. In the intermediate group (n = 17) hyperreactivity, sensory interests and sensory/motor issues were significantly elevated in relation to the first group, but not hyporeactivity. In a high frequency subgroup (n = 17) all subscale scores were significantly elevated and co-occurrence of hyper- and hyporeactivity was evident...
December 5, 2016: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/27915149/trans-and-paracellular-calcium-transport-along-the-small-and-large-intestine-in-horses
#2
M R Wilkens, L Marholt, N Eigendorf, A S Muscher-Banse, K Feige, B Schröder, G Breves, A Cehak
Intestinal calcium absorption plays a key role in the maintenance of calcium homeostasis and may either occur by paracellular or transcellular mechanisms. The horse has some unique peculiarities in calcium homeostasis compared to other species including a high absorptive capacity for calcium in the intestine, high plasma calcium concentrations, high renal excretion, and low plasma concentrations of vitamin D metabolites. So far, knowledge about the underlying mechanisms and the regulation of intestinal calcium absorption is still limited concerning this species...
November 30, 2016: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/27914209/methodological-flaws-introduce-strong-bias-into-molecular-analysis-of-microbial-populations
#3
Niclas Krakat, Reshma Anjum, Burak Demirel, Patrick Schröder
AIMS: Here we report how different cell disruption methods, PCR primers and in-silico analyses can seriously bias results from microbial population studies, with consequences for the credibility and reproducibility of the findings. Our results emphasize the pitfalls of commonly used experimental methods that can seriously weaken the interpretation of results. METHODS AND RESULTS: Four different cell lysis methods, three commonly used primer pairs and various computer-based analyses were applied to investigate the microbial diversity of a fermentation sample composed of chicken dung...
December 3, 2016: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/27911333/the-%C3%A2-strand-ryhming-test-is-not-a-feasible-measure-in-ambulatory-patients-with%C3%A2-amyotrophic-lateral-sclerosis
#4
Annerieke C van Groenestijn, Olaf Verschuren, Carin D Schröder, Leonard H van den Berg, Johanna M A Visser-Meily
BACKGROUND: Ambulatory patients with Amyotrophic Lateral Sclerosis (ALS) show a decreased aerobic capacity which may hamper the ability to perform activities of daily living. A standardized measure, however, for assessing aerobic capacity in patients with ALS during the disease course, is lacking. OBJECTIVE: To examine the feasibility of the Åstrand-Ryhming (ÅR) test protocol longitudinally in ambulatory patients with amyotrophic lateral sclerosis (ALS). METHODS: Seven ambulatory male patients with spinal ALS onset were assessed at baseline and at 4, 7 and 10 months' follow-up...
November 29, 2016: Journal of Neuromuscular Diseases
https://www.readbyqxmd.com/read/27910389/overview-of-diagnostic-performance-and-results-for-the-first-operation-phase-in-wendelstein-7-x-invited
#5
M Krychowiak, A Adnan, A Alonso, T Andreeva, J Baldzuhn, T Barbui, M Beurskens, W Biel, C Biedermann, B D Blackwell, H S Bosch, S Bozhenkov, R Brakel, T Bräuer, B Brotas de Carvalho, R Burhenn, B Buttenschön, A Cappa, G Cseh, A Czarnecka, A Dinklage, P Drews, A Dzikowicka, F Effenberg, M Endler, V Erckmann, T Estrada, O Ford, T Fornal, H Frerichs, G Fuchert, J Geiger, O Grulke, J H Harris, H J Hartfuß, D Hartmann, D Hathiramani, M Hirsch, U Höfel, S Jabłoński, M W Jakubowski, J Kaczmarczyk, T Klinger, S Klose, J Knauer, G Kocsis, R König, P Kornejew, A Krämer-Flecken, N Krawczyk, T Kremeyer, I Książek, M Kubkowska, A Langenberg, H P Laqua, M Laux, S Lazerson, Y Liang, S C Liu, A Lorenz, A O Marchuk, S Marsen, V Moncada, D Naujoks, H Neilson, O Neubauer, U Neuner, H Niemann, J W Oosterbeek, M Otte, N Pablant, E Pasch, T Sunn Pedersen, F Pisano, K Rahbarnia, L Ryć, O Schmitz, S Schmuck, W Schneider, T Schröder, H Schuhmacher, B Schweer, B Standley, T Stange, L Stephey, J Svensson, T Szabolics, T Szepesi, H Thomsen, J-M Travere, H Trimino Mora, H Tsuchiya, G M Weir, U Wenzel, A Werner, B Wiegel, T Windisch, R Wolf, G A Wurden, D Zhang, A Zimbal, S Zoletnik
Wendelstein 7-X, a superconducting optimized stellarator built in Greifswald/Germany, started its first plasmas with the last closed flux surface (LCFS) defined by 5 uncooled graphite limiters in December 2015. At the end of the 10 weeks long experimental campaign (OP1.1) more than 20 independent diagnostic systems were in operation, allowing detailed studies of many interesting plasma phenomena. For example, fast neutral gas manometers supported by video cameras (including one fast-frame camera with frame rates of tens of kHz) as well as visible cameras with different interference filters, with field of views covering all ten half-modules of the stellarator, discovered a MARFE-like radiation zone on the inboard side of machine module 4...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27906244/complete-spatiotemporal-characterization-and-optical-transfer-matrix-inversion-of-a-420-mode-fiber
#6
Joel Carpenter, Benjamin J Eggleton, Jochen Schröder
The ability to measure a scattering medium's optical transfer matrix, the mapping between any spatial input and output, has enabled applications such as imaging to be performed through media which would otherwise be opaque due to scattering. However, the scattering of light occurs not just in space, but also in time. We complete the characterization of scatter by extending optical transfer matrix methods into the time domain, allowing any spatiotemporal input state at one end to be mapped directly to its corresponding spatiotemporal output state...
December 1, 2016: Optics Letters
https://www.readbyqxmd.com/read/27906079/muscle-specific-loss-of-bmal1-leads-to-disrupted-tissue-glucose-metabolism-and-systemic-glucose-homeostasis
#7
Brianna D Harfmann, Elizabeth A Schroder, Maureen T Kachman, Brian A Hodge, Xiping Zhang, Karyn A Esser
BACKGROUND: Diabetes is the seventh leading cause of death in the USA, and disruption of circadian rhythms is gaining recognition as a contributing factor to disease prevalence. This disease is characterized by hyperglycemia and glucose intolerance and symptoms caused by failure to produce and/or respond to insulin. The skeletal muscle is a key insulin-sensitive metabolic tissue, taking up ~80 % of postprandial glucose. To address the role of the skeletal muscle molecular clock to insulin sensitivity and glucose tolerance, we generated an inducible skeletal muscle-specific Bmal1 (-/-) mouse (iMSBmal1 (-/-))...
March 30, 2016: Skeletal Muscle
https://www.readbyqxmd.com/read/27905661/artificial-cartilage-bio-matrix-formed-of-hyaluronic-acid-and-mg2-polyphosphate
#8
X Wang, M Ackermann, E Tolba, M Neufurth, F Wurm, Q Feng, S Wang, H C Schröder, W E Müller
Here we show that inorganic polyphosphate (polyP), a polyanionic metabolic regulator consisting of multiple phosphate residues linked by energy-rich phosphoanhydride bonds, is present in the synovial fluid. In a biomimetic approach, to enhance cartilage synthesis and regeneration, we prepared amorphous polyP microparticles with Mg2+ as counterions. The particles were characterised by X-ray diffraction (XRD), energy-dispersive X-ray (EDX) and Fourier transformed infrared spectroscopic (FTIR) analyses. Similar particles were obtained after addition of Mg2+ ions to a solution containing hyaluronic acid, as a major component of the synovial fluid, and soluble Na-polyP...
November 29, 2016: European Cells & Materials
https://www.readbyqxmd.com/read/27900520/nuclear-medicine-imaging-of-multiple-myeloma-particularly-in-the-relapsed-setting
#9
REVIEW
Esther G M de Waal, Andor W J M Glaudemans, Carolien P Schröder, Edo Vellenga, Riemer H J A Slart
Multiple myeloma (MM) is characterized by a monoclonal plasma cell population in the bone marrow. Lytic lesions occur in up to 90 % of patients. For many years, whole-body X-ray (WBX) was the method of choice for detecting skeleton abnormalities. However, the value of WBX in relapsing disease is limited because lesions persist post-treatment, which restricts the capacity to distinguish between old, inactive skeletal lesions and new, active ones. Therefore, alternative techniques are necessary to visualize disease activity...
November 29, 2016: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27900347/isolated-dysphagia-as-initial-sign-of-anti-iglon5-syndrome
#10
Jens Burchard Schröder, Nico Melzer, Tobias Ruck, Anna Heidbreder, Ilka Kleffner, Ralf Dittrich, Paul Muhle, Tobias Warnecke, Rainer Dziewas
OBJECTIVE: To report on dysphagia as initial sign in a case of anti-IgLON5 syndrome and provide an overview of the current literature. METHODS: The diagnostic workup included cerebral MRI, fiber optic endoscopic evaluation of swallowing (FEES) with the FEES tensilon test, a videofluoroscopic swallowing study, evoked potentials and peripheral nerve conduction studies, polysomnography, lumbar puncture, and screening for neural autoantibodies. A systematic review of all published cases of IgLON5 syndrome is provided...
January 2017: Neurology® Neuroimmunology & Neuroinflammation
https://www.readbyqxmd.com/read/27896354/structural-and-dynamic-studies-of-substrate-binding-in-porous-metal-organic-frameworks
#11
REVIEW
Timothy L Easun, Florian Moreau, Yong Yan, Sihai Yang, Martin Schröder
Porous metal-organic frameworks (MOFs) are the subject of considerable research interest because of their high porosity and capability of specific binding to small molecules, thus underpinning a wide range of materials functions such as gas adsorption, separation, drug delivery, catalysis, and sensing. MOFs, constructed by the designed assembly of metal ions and functional organic linkers, are an emerging class of porous materials with extended porous structures containing periodic binding sites. MOFs thus provide a new platform for the study of the chemistry and reactivity of small molecules in confined pores using advanced diffraction and spectroscopic techniques...
November 29, 2016: Chemical Society Reviews
https://www.readbyqxmd.com/read/27887755/use-of-ventilator-utilization-ratio-for-stratifying-alcohol-based-hand-rub-consumption-data-to-improve-surveillance-on-intensive-care-units
#12
W Wetzker, K Bunte-Schönberger, J Walter, C Schröder, P Gastmeier, C Reichardt
BACKGROUND: Germany has established a nationwide surveillance system of alcohol-based hand-rub consumption (AHC) per patient-day in hospital settings as a surrogate parameter for hand hygiene (HH) compliance. Analysis of AHC data in intensive care units (ICUs) shows not only a wide range of consumption between units of different specialties, but also within units of one specialty. This seems to reflect variation in the number of HH opportunities per patient-day between ICUs due to variation in complexity of care...
November 3, 2016: Journal of Hospital Infection
https://www.readbyqxmd.com/read/27879266/threshold-analysis-and-biodistribution-of-fluorescently-labeled-bevacizumab-in-human-breast-cancer
#13
Maximillian Koch, Johannes S de Jong, Jürgen Glatz, Panagiotis Symvoulidis, Laetitia E Lamberts, Arthur Adams, Mariëtte E G Kranendonk, Anton G T Terwisscha van Scheltinga, Michaela Aichler, Liesbeth Jansen, Jakob de Vries, Marjolijn N Lub-de Hooge, Carolina P Schröder, Annelies Jorritsma-Smit, Matthijs D Linssen, Esther de Boer, Bert van der Vegt, Wouter B Nagengast, Sjoerd G Elias, Sabrina Oliveira, Arjen Witkamp, Willem P Th M Mali, Elsken van der Wall, Beatriz P Garcia-Allende, Paul J Van Diest, Elisabeth G de Vries, Axel Walch, Gooitzen M van Dam, Vasilis Ntziachristos
In vivo tumor labeling with fluorescent agents may assist endoscopic and surgical guidance for cancer therapy as well as create opportunities to directly observe cancer biology in patients. However, malignant and non-malignant tissues are usually distinguished on fluorescence images by applying empirically determined fluorescence intensity thresholds. Here we report the development of fSTREAM, a set of analytic methods designed to streamline the analysis of surgically excised breast tissues by collecting and statistically processing hybrid multi-scale fluorescence, color, and histology readouts toward precision fluorescence imaging...
November 22, 2016: Cancer Research
https://www.readbyqxmd.com/read/27868277/outpatient-antidepressant-drug-use-in-children-and-adolescents-in-germany-between-2004-and-2011
#14
Carsten Schröder, Michael Dörks, Bianca Kollhorst, Tilo Blenk, Ralf W Dittmann, Edeltraut Garbe, Oliver Riedel
PURPOSE: Recent studies on the utilization of antidepressant drugs in minors are scarce, methodologically limited, and do not factor in off-label use sufficiently. Beyond that, little is known about the short treatment durations that have been observed for many young antidepressant users. The present study examined antidepressant use in pediatric patients aged 0 to 17 years over time, investigated changes regarding the prescribed drugs, analyzed underlying diagnoses, and assessed the rate of off-label use...
November 20, 2016: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/27865902/the-regression-discontinuity-design-showed-to-be-a-valid-alternative-to-a-randomized-controlled-trial-for-estimating-treatment-effects
#15
Iris L Maas, Sandra Nolte, Otto B Walter, Thomas Berger, Martin Hautzinger, Fritz Hohagen, Wolfgang Lutz, Björn Meyer, Johanna Schröder, Christina Späth, Jan Philipp Klein, Steffen Moritz, Matthias Rose
OBJECTIVE: To compare treatment effect estimates obtained from a Regression Discontinuity (RD) design with results from an actual randomized controlled trial (RCT). STUDY DESIGN AND SETTING: Data from an RCT (EVIDENT), which studied the effect of an internet intervention on depressive symptoms measured with the Patient Health Questionnaire (PHQ-9), were used to perform an RD analysis, in which treatment allocation was determined by a cut-off value at baseline (PHQ-9=10)...
November 16, 2016: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/27863990/cytochrome-p450-enzymes-but-not-nadph-oxidases-are-the-source-of-the-nadph-dependent-lucigenin-chemiluminescence-in-membrane-assays
#16
Flávia Rezende, Kim-Kristin Prior, Oliver Löwe, Ilka Wittig, Valentina Strecker, Franziska Moll, Valeska Helfinger, Frank Schnütgen, Nina Kurrle, Frank Wempe, Maria Walter, Sven Zukunft, Bert Luck, Ingrid Fleming, Norbert Weissmann, Ralf P Brandes, Katrin Schröder
: Measuring NADPH oxidase (Nox)-derived reactive oxygen species (ROS) in living tissues and cells is a constant challenge. All probes available display limitations regarding sensitivity, specificity or demand highly specialized detection techniques. In search for a presumably easy, versatile, sensitive and specific technique, numerous studies have used NADPH-stimulated assays in membrane fractions which have been suggested to reflect Nox activity. However, we previously found an unaltered activity with these assays in triple Nox knockout mouse (Nox1-Nox2-Nox4(-/-)) tissue and cells compared to wild type...
November 15, 2016: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/27858429/testing-hadronic-interactions-at-ultrahigh-energies-with-air-showers-measured-by-the-pierre-auger-observatory
#17
A Aab, P Abreu, M Aglietta, E J Ahn, I Al Samarai, I F M Albuquerque, I Allekotte, J D Allen, P Allison, A Almela, J Alvarez Castillo, J Alvarez-Muñiz, M Ambrosio, G A Anastasi, L Anchordoqui, B Andrada, S Andringa, C Aramo, F Arqueros, N Arsene, H Asorey, P Assis, J Aublin, G Avila, A M Badescu, C Baus, J J Beatty, K H Becker, J A Bellido, C Berat, M E Bertaina, X Bertou, P L Biermann, P Billoir, J Biteau, S G Blaess, A Blanco, J Blazek, C Bleve, H Blümer, M Boháčová, D Boncioli, C Bonifazi, N Borodai, A M Botti, J Brack, I Brancus, T Bretz, A Bridgeman, F L Briechle, P Buchholz, A Bueno, S Buitink, M Buscemi, K S Caballero-Mora, B Caccianiga, L Caccianiga, A Cancio, F Canfora, L Caramete, R Caruso, A Castellina, G Cataldi, L Cazon, R Cester, A G Chavez, A Chiavassa, J A Chinellato, J C Chirinos Diaz, J Chudoba, R W Clay, R Colalillo, A Coleman, L Collica, M R Coluccia, R Conceição, F Contreras, M J Cooper, S Coutu, C E Covault, J Cronin, R Dallier, S D'Amico, B Daniel, S Dasso, K Daumiller, B R Dawson, R M de Almeida, S J de Jong, G De Mauro, J R T de Mello Neto, I De Mitri, J de Oliveira, V de Souza, J Debatin, L Del Peral, O Deligny, N Dhital, C Di Giulio, A Di Matteo, M L Díaz Castro, F Diogo, C Dobrigkeit, J C D'Olivo, A Dorofeev, R C Dos Anjos, M T Dova, A Dundovic, J Ebr, R Engel, M Erdmann, M Erfani, C O Escobar, J Espadanal, A Etchegoyen, H Falcke, K Fang, G R Farrar, A C Fauth, N Fazzini, A P Ferguson, B Fick, J M Figueira, A Filevich, A Filipčič, O Fratu, M M Freire, T Fujii, A Fuster, F Gallo, B García, D Garcia-Pinto, F Gate, H Gemmeke, A Gherghel-Lascu, P L Ghia, U Giaccari, M Giammarchi, M Giller, D Głas, C Glaser, H Glass, G Golup, M Gómez Berisso, P F Gómez Vitale, N González, B Gookin, J Gordon, A Gorgi, P Gorham, P Gouffon, N Griffith, A F Grillo, T D Grubb, F Guarino, G P Guedes, M R Hampel, P Hansen, D Harari, T A Harrison, J L Harton, Q Hasankiadeh, A Haungs, T Hebbeker, D Heck, P Heimann, A E Herve, G C Hill, C Hojvat, N Hollon, E Holt, P Homola, J R Hörandel, P Horvath, M Hrabovský, T Huege, J Hulsman, A Insolia, P G Isar, I Jandt, S Jansen, C Jarne, J A Johnsen, M Josebachuili, A Kääpä, O Kambeitz, K H Kampert, P Kasper, I Katkov, B Keilhauer, E Kemp, R M Kieckhafer, H O Klages, M Kleifges, J Kleinfeller, R Krause, N Krohm, D Kuempel, G Kukec Mezek, N Kunka, A Kuotb Awad, D LaHurd, L Latronico, M Lauscher, P Lautridou, P Lebrun, R Legumina, M A Leigui de Oliveira, A Letessier-Selvon, I Lhenry-Yvon, K Link, L Lopes, R López, A López Casado, A Lucero, M Malacari, M Mallamaci, D Mandat, P Mantsch, A G Mariazzi, V Marin, I C Mariş, G Marsella, D Martello, H Martinez, O Martínez Bravo, J J Masías Meza, H J Mathes, S Mathys, J Matthews, J A J Matthews, G Matthiae, D Maurizio, E Mayotte, P O Mazur, C Medina, G Medina-Tanco, V B B Mello, D Melo, A Menshikov, S Messina, M I Micheletti, L Middendorf, I A Minaya, L Miramonti, B Mitrica, L Molina-Bueno, S Mollerach, F Montanet, C Morello, M Mostafá, C A Moura, G Müller, M A Muller, S Müller, I Naranjo, S Navas, P Necesal, L Nellen, A Nelles, J Neuser, P H Nguyen, M Niculescu-Oglinzanu, M Niechciol, L Niemietz, T Niggemann, D Nitz, D Nosek, V Novotny, H Nožka, L A Núñez, L Ochilo, F Oikonomou, A Olinto, D Pakk Selmi-Dei, M Palatka, J Pallotta, P Papenbreer, G Parente, A Parra, T Paul, M Pech, F Pedreira, J Pękala, R Pelayo, J Peña-Rodriguez, I M Pepe, L A S Pereira, L Perrone, E Petermann, C Peters, S Petrera, J Phuntsok, R Piegaia, T Pierog, P Pieroni, M Pimenta, V Pirronello, M Platino, M Plum, C Porowski, R R Prado, P Privitera, M Prouza, E J Quel, S Querchfeld, S Quinn, J Rautenberg, O Ravel, D Ravignani, B Revenu, J Ridky, M Risse, P Ristori, V Rizi, W Rodrigues de Carvalho, J Rodriguez Rojo, M D Rodríguez-Frías, D Rogozin, J Rosado, M Roth, E Roulet, A C Rovero, S J Saffi, A Saftoiu, H Salazar, A Saleh, F Salesa Greus, G Salina, J D Sanabria Gomez, F Sánchez, P Sanchez-Lucas, E M Santos, E Santos, F Sarazin, B Sarkar, R Sarmento, C Sarmiento-Cano, R Sato, C Scarso, M Schauer, V Scherini, H Schieler, D Schmidt, O Scholten, H Schoorlemmer, P Schovánek, F G Schröder, A Schulz, J Schulz, J Schumacher, S J Sciutto, A Segreto, M Settimo, A Shadkam, R C Shellard, G Sigl, O Sima, A Śmiałkowski, R Šmída, G R Snow, P Sommers, S Sonntag, J Sorokin, R Squartini, D Stanca, S Stanič, J Stapleton, J Stasielak, F Strafella, A Stutz, F Suarez, M Suarez Durán, T Sudholz, T Suomijärvi, A D Supanitsky, M S Sutherland, J Swain, Z Szadkowski, O A Taborda, A Tapia, A Tepe, V M Theodoro, C Timmermans, C J Todero Peixoto, L Tomankova, B Tomé, A Tonachini, G Torralba Elipe, D Torres Machado, P Travnicek, M Trini, R Ulrich, M Unger, M Urban, A Valbuena-Delgado, J F Valdés Galicia, I Valiño, L Valore, G van Aar, P van Bodegom, A M van den Berg, A van Vliet, E Varela, B Vargas Cárdenas, G Varner, J R Vázquez, R A Vázquez, D Veberič, V Verzi, J Vicha, M Videla, L Villaseñor, S Vorobiov, H Wahlberg, O Wainberg, D Walz, A A Watson, M Weber, A Weindl, L Wiencke, H Wilczyński, T Winchen, D Wittkowski, B Wundheiler, S Wykes, L Yang, T Yapici, D Yelos, E Zas, D Zavrtanik, M Zavrtanik, A Zepeda, B Zimmermann, M Ziolkowski, Z Zong, F Zuccarello
Ultrahigh energy cosmic ray air showers probe particle physics at energies beyond the reach of accelerators. Here we introduce a new method to test hadronic interaction models without relying on the absolute energy calibration, and apply it to events with primary energy 6-16 EeV (E_{CM}=110-170  TeV), whose longitudinal development and lateral distribution were simultaneously measured by the Pierre Auger Observatory. The average hadronic shower is 1.33±0.16 (1.61±0.21) times larger than predicted using the leading LHC-tuned models EPOS-LHC (QGSJetII-04), with a corresponding excess of muons...
November 4, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27855674/disk-displacement-eccentric-condylar-position-osteoarthrosis-misnomers-for-variations-of-normality-results-and-interpretations-from-an-mri-study-in-two-age-cohorts
#18
Jens C Türp, Anna Schlenker, Johannes Schröder, Marco Essig, Marc Schmitter
BACKGROUND: Clinical decision-making and prognostic statements in individuals with manifest or suspected temporomandibular disorders (TMDs) may involve assessment of (a) the position of articular disc relative to the mandibular condyle, (b) the location of the condyle relative to the temporal joint surfaces, and (c) the depth of the glenoid fossa of the temporomandibular joints (TMJs). The aim of this study was twofold: (1) Determination of the prevalence of these variables in two representative population-based birth cohorts...
November 17, 2016: BMC Oral Health
https://www.readbyqxmd.com/read/27853266/interaction-control-to-synchronize-non-synchronizable-networks
#19
Malte Schröder, Sagar Chakraborty, Dirk Witthaut, Jan Nagler, Marc Timme
Synchronization constitutes one of the most fundamental collective dynamics across networked systems and often underlies their function. Whether a system may synchronize depends on the internal unit dynamics as well as the topology and strength of their interactions. For chaotic units with certain interaction topologies synchronization might be impossible across all interaction strengths, meaning that these networks are non-synchronizable. Here we propose the concept of interaction control, generalizing transient uncoupling, to induce desired collective dynamics in complex networks and apply it to synchronize even such non-synchronizable systems...
November 17, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27848944/clinical-exome-sequencing-results-from-2819-samples-reflecting-1000-families
#20
Daniel Trujillano, Aida M Bertoli-Avella, Krishna Kumar Kandaswamy, Maximilian Er Weiss, Julia Köster, Anett Marais, Omid Paknia, Rolf Schröder, Jose Maria Garcia-Aznar, Martin Werber, Oliver Brandau, Maria Calvo Del Castillo, Caterina Baldi, Karen Wessel, Shivendra Kishore, Nahid Nahavandi, Wafaa Eyaid, Muhammad Talal Al Rifai, Ahmed Al-Rumayyan, Waleed Al-Twaijri, Ali Alothaim, Amal Alhashem, Nouriya Al-Sannaa, Mohammed Al-Balwi, Majid Alfadhel, Arndt Rolfs, Rami Abou Jamra
We report our results of 1000 diagnostic WES cases based on 2819 sequenced samples from 54 countries with a wide phenotypic spectrum. Clinical information given by the requesting physicians was translated to HPO terms. WES processes were performed according to standardized settings. We identified the underlying pathogenic or likely pathogenic variants in 307 families (30.7%). In further 253 families (25.3%) a variant of unknown significance, possibly explaining the clinical symptoms of the index patient was identified...
November 16, 2016: European Journal of Human Genetics: EJHG
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