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https://www.readbyqxmd.com/read/28734065/fdg-pet-dopamine-transporter-spect-and-olfaction-combining-biomarkers-in-rem-sleep-behavior-disorder
#1
Sanne K Meles, David Vadasz, Remco J Renken, Elisabeth Sittig-Wiegand, Geert Mayer, Candan Depboylu, Kathrin Reetz, Sebastiaan Overeem, Angelique Pijpers, Fransje E Reesink, Teus van Laar, Lisette Heinen, Laura K Teune, Helmut Höffken, Marcus Luster, Karl Kesper, Sofie M Adriaanse, Jan Booij, Klaus L Leenders, Wolfgang H Oertel
BACKGROUND: Idiopathic REM sleep behavior disorder is a prodromal stage of Parkinson's disease and dementia with Lewy bodies. Hyposmia, reduced dopamine transporter binding, and expression of the brain metabolic PD-related pattern were each associated with increased risk of conversion to PD. The objective of this study was to study the relationship between the PD-related pattern, dopamine transporter binding, and olfaction in idiopathic REM sleep behavior disorder. METHODS: In this cross-sectional study, 21 idiopathic REM sleep behavior disorder subjects underwent (18) F-fluorodeoxyglucose PET, dopamine transporter imaging, and olfactory testing...
July 22, 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28705079/how-to-define-the-hemodynamic-significance-of-an-equivocal-iliofemoral-artery-stenosis-review-of-literature-and-outcomes-of-an-international-questionnaire
#2
S W de Boer, Sgh Heinen, Daf van den Heuvel, F N van de Vosse, Jppm de Vries
Purpose The goal of the study was to review current literature regarding the diagnosis of equivocal (50-70%) iliofemoral artery stenosis and compare these findings with the daily practice of an international panel of endovascular experts. Methods The Medline Database was searched for relevant publications, and an electronic survey was sent to experts in the field covering the following topics: definition of an equivocal iliofemoral artery stenosis, angiographic visualization and investigation protocols of an equivocal stenosis, intra-arterial pressure measurements, and definition of hemodynamic significance of an equivocal iliofemoral artery stenosis using a physiologic measure...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/28557247/european-consensus-on-the-concepts-and-measurement-of-the-pathophysiological-neuromuscular-responses-to-passive-muscle-stretch
#3
J C van den Noort, L Bar-On, E Aertbeliën, M Bonikowski, S M Braendvik, E W Broström, A I Buizer, J H Burridge, A van Campenhout, B Dan, J F Fleuren, S Grunt, F Heinen, H L Horemans, C Jansen, A Kranzl, B K Krautwurst, M van der Krogt, S Lerma Lara, C M Lidbeck, J-P Lin, I Martinez, C Meskers, D Metaxiotis, G Molenaers, D A Patikas, O Rémy-Néris, K Roeleveld, A P Shortland, J Sikkens, L Sloot, R J Vermeulen, C Wimmer, A S Schröder, S Schless, J G Becher, K Desloovere, J Harlaar
BACKGROUND AND PURPOSE: To support clinical decision-making in central neurological disorders, a physical examination is used to assess responses to passive muscle stretch. However, what exactly is being assessed is expressed and interpreted in different ways. A clear diagnostic framework is lacking. Therefore, the aim was to arrive at unambiguous terminology about the concepts and measurement around pathophysiological neuromuscular response to passive muscle stretch. METHODS: During two consensus meetings, 37 experts from 12 European countries filled online questionnaires based on a Delphi approach, followed by plenary discussion after rounds...
July 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28537583/impact-of-the-n-6-n-3-long-chain-pufa-ratio-during-pregnancy-and-lactation-on-offspring-neurodevelopment-5-year-follow-up-of-a-randomized-controlled-trial
#4
C Brei, L Stecher, S Brunner, R Ensenauer, F Heinen, P D Wagner, J Hermsdörfer, H Hauner
BACKGROUND/OBJECTIVES: Evidence regarding the effect of n-3 long-chain polyunsaturated fatty acid (LCPUFA) supplementation during pregnancy on offspring's neurodevelopment is not conclusive. SUBJECTS/METHODS: In this analysis, the effect of a reduced n-6:n-3 LCPUFA ratio in the diet of pregnant/lactating women (1.2 g n-3 LCPUFA together with an arachidonic acid (AA)-balanced diet between 15th wk of gestation-4 months postpartum vs control diet) on child neurodevelopment at 4 and 5 years of age was assessed...
May 24, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28485198/pros-and-cons-of-3d-image-fusion-in-endovascular-aortic-repair-a-systematic-review-and-meta-analysis
#5
Seline R Goudeketting, Stefan G H Heinen, Çağdaş Ünlü, Daniel A F van den Heuvel, Jean-Paul P M de Vries, Marco J van Strijen, Anna M Sailer
PURPOSE: To systematically review and meta-analyze the added value of 3-dimensional (3D) image fusion technology in endovascular aortic repair for its potential to reduce contrast media volume, radiation dose, procedure time, and fluoroscopy time. METHODS: Electronic databases were systematically searched for studies published between January 2010 and March 2016 that included a control group describing 3D fusion imaging in endovascular aortic procedures. Two independent reviewers assessed the methodological quality of the included studies and extracted data on iodinated contrast volume, radiation dose, procedure time, and fluoroscopy time...
May 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/28089889/myc-drives-progression-of-small-cell-lung-cancer-to-a-variant-neuroendocrine-subtype-with-vulnerability-to-aurora-kinase-inhibition
#6
Gurkan Mollaoglu, Matthew R Guthrie, Stefanie Böhm, Johannes Brägelmann, Ismail Can, Paul M Ballieu, Annika Marx, Julie George, Christine Heinen, Milind D Chalishazar, Haixia Cheng, Abbie S Ireland, Kendall E Denning, Anandaroop Mukhopadhyay, Jeffery M Vahrenkamp, Kristofer C Berrett, Timothy L Mosbruger, Jun Wang, Jessica L Kohan, Mohamed E Salama, Benjamin L Witt, Martin Peifer, Roman K Thomas, Jason Gertz, Jane E Johnson, Adi F Gazdar, Robert J Wechsler-Reya, Martin L Sos, Trudy G Oliver
Loss of the tumor suppressors RB1 and TP53 and MYC amplification are frequent oncogenic events in small cell lung cancer (SCLC). We show that Myc expression cooperates with Rb1 and Trp53 loss in the mouse lung to promote aggressive, highly metastatic tumors, that are initially sensitive to chemotherapy followed by relapse, similar to human SCLC. Importantly, MYC drives a neuroendocrine-low "variant" subset of SCLC with high NEUROD1 expression corresponding to transcriptional profiles of human SCLC. Targeted drug screening reveals that SCLC with high MYC expression is vulnerable to Aurora kinase inhibition, which, combined with chemotherapy, strongly suppresses tumor progression and increases survival...
February 13, 2017: Cancer Cell
https://www.readbyqxmd.com/read/27992161/thermodynamic-ground-states-of-complex-oxide-heterointerfaces
#7
F Gunkel, S Hoffmann-Eifert, R A Heinen, D V Christensen, Y Z Chen, N Pryds, R Waser, R Dittmann
The formation mechanism of 2-dimensional electron gases (2DEGs) at heterointerfaces between nominally insulating oxides is addressed with a thermodynamical approach. We provide a comprehensive analysis of the thermodynamic ground states of various 2DEG systems directly probed in high temperature equilibrium conductivity measurements. We unambiguously identify two distinct classes of oxide heterostructures: For epitaxial perovskite/perovskite heterointerfaces (LaAlO3/SrTiO3, NdGaO3/SrTiO3, and (La,Sr)(Al,Ta)O3/SrTiO3), we find the 2DEG formation being based on charge transfer into the interface, stabilized by the electric field in the space charge region...
December 19, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27471010/translational-profiling-of-retinal-ganglion-cell-optic-nerve-regeneration-in-xenopus-laevis
#8
G B Whitworth, B C Misaghi, D M Rosenthal, E A Mills, D J Heinen, A H Watson, C W Ives, S H Ali, K Bezold, N Marsh-Armstrong, F L Watson
Unlike adult mammals, adult frogs regrow their optic nerve following a crush injury, making Xenopus laevis a compelling model for studying the molecular mechanisms that underlie neuronal regeneration. Using Translational Ribosome Affinity Purification (TRAP), a method to isolate ribosome-associated mRNAs from a target cell population, we have generated a transcriptional profile by RNA-Seq for retinal ganglion cells (RGC) during the period of recovery following an optic nerve injury. Based on bioinformatic analysis using the Xenopus laevis 9...
June 15, 2017: Developmental Biology
https://www.readbyqxmd.com/read/27267887/strategies-in-primary-healthcare-to-implement-early-identification-of-risky-alcohol-consumption-why-do-they-work-or-not-a-qualitative-evaluation-of-the-odhin-study
#9
M Keurhorst, M Heinen, J Colom, C Linderoth, U Müssener, K Okulicz-Kozaryn, J Palacio-Vieira, L Segura, F Silfversparre, L Słodownik, E Sorribes, M Laurant, M Wensing
BACKGROUND: Screening and brief interventions (SBI) in primary healthcare are cost-effective in risky drinkers, yet they are not offered to all eligible patients. This qualitative study aimed to provide more insight into the factors and mechanisms of why, how, for whom and under what circumstances implementation strategies work or do not work in increasing SBI. METHODS: Semi-structured interviews were conducted between February and July 2014 with 40 GPs and 28 nurses in Catalonia, the Netherlands, Poland, and Sweden...
June 7, 2016: BMC Family Practice
https://www.readbyqxmd.com/read/26840047/igsf1-deficiency-lessons-from-an-extensive-case-series-and-recommendations-for-clinical-management
#10
S D Joustra, C A Heinen, N Schoenmakers, M Bonomi, B E P B Ballieux, M-O Turgeon, D J Bernard, E Fliers, A S P van Trotsenburg, M Losekoot, L Persani, J M Wit, N R Biermasz, A M Pereira, W Oostdijk
Clinical and biochemical characteristics of 69 male patients and 56 female IGSF1 mutation carriers were collected, providing recommendations for mutational analysis, endocrine work-up, and long-term care.
April 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/26824124/health-promotion-contrarians-luther-terry-halbert-l-dunn-robert-f-allen-and-edward-m-kennedy
#11
Marc Manley, Donald B Ardell, Judd R Allen, LuAnn Heinen
No abstract text is available yet for this article.
November 2015: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/26371681/classical-liquids-in-fractal-dimension
#12
Marco Heinen, Simon K Schnyder, John F Brady, Hartmut Löwen
We introduce fractal liquids by generalizing classical liquids of integer dimensions d=1,2,3 to a noninteger dimension dl. The particles composing the liquid are fractal objects and their configuration space is also fractal, with the same dimension. Realizations of our generic model system include microphase separated binary liquids in porous media, and highly branched liquid droplets confined to a fractal polymer backbone in a gel. Here, we study the thermodynamics and pair correlations of fractal liquids by computer simulation and semianalytical statistical mechanics...
August 28, 2015: Physical Review Letters
https://www.readbyqxmd.com/read/26277734/severity-of-polymicrobial-sepsis-modulates-mitochondrial-function-in-rat-liver
#13
A Herminghaus, F Barthel, A Heinen, C Beck, C Vollmer, I Bauer, A Weidinger, A V Kozlov, O Picker
Mitochondrial dysfunction is assumed to be an important contributor to multi organ dysfunction syndrome. Here, the effects of varying degrees of sepsis on hepatic mitochondrial function were investigated. Moderate or more severe sepsis was induced in rats using a colon ascendens stent peritonitis (CASP)-model (16 G and 14 G stent respectively). Respiratory control ratio (RCR) was significantly higher in the 16 G-group and unchanged in the 14 G-group compared with healthy controls. The ADP/O ratio was similar in all groups...
September 2015: Mitochondrion
https://www.readbyqxmd.com/read/26214711/transgenic-wheat-expressing-a-barley-udp-glucosyltransferase-detoxifies-deoxynivalenol-and-provides-high-levels-of-resistance-to-fusarium-graminearum
#14
Xin Li, Sanghyun Shin, Shane Heinen, Ruth Dill-Macky, Franz Berthiller, Natalya Nersesian, Thomas Clemente, Susan McCormick, Gary J Muehlbauer
Fusarium head blight (FHB), mainly caused by Fusarium graminearum, is a devastating disease of wheat that results in economic losses worldwide. During infection, F. graminearum produces trichothecene mycotoxins, including deoxynivalenol (DON), that increase fungal virulence and reduce grain quality. Transgenic wheat expressing a barley UDP-glucosyltransferase (HvUGT13248) were developed and evaluated for FHB resistance, DON accumulation, and the ability to metabolize DON to the less toxic DON-3-O-glucoside (D3G)...
November 2015: Molecular Plant-microbe Interactions: MPMI
https://www.readbyqxmd.com/read/25995705/development-of-a-general-analysis-and-unfolding-scheme-and-its-application-to-measure-the-energy-spectrum-of-atmospheric-neutrinos-with-icecube-icecube-collaboration
#15
M G Aartsen, M Ackermann, J Adams, J A Aguilar, M Ahlers, M Ahrens, D Altmann, T Anderson, C Arguelles, T C Arlen, J Auffenberg, X Bai, S W Barwick, V Baum, J J Beatty, J Becker Tjus, K-H Becker, S BenZvi, P Berghaus, D Berley, E Bernardini, A Bernhard, D Z Besson, G Binder, D Bindig, M Bissok, E Blaufuss, J Blumenthal, D J Boersma, C Bohm, F Bos, D Bose, S Böser, O Botner, L Brayeur, H P Bretz, A M Brown, J Casey, M Casier, E Cheung, D Chirkin, A Christov, B Christy, K Clark, L Classen, F Clevermann, S Coenders, D F Cowen, A H Cruz Silva, M Danninger, J Daughhetee, J C Davis, M Day, J P A M de André, C De Clercq, S De Ridder, P Desiati, K D de Vries, M de With, T DeYoung, J C Díaz-Vélez, M Dunkman, R Eagan, B Eberhardt, B Eichmann, J Eisch, S Euler, P A Evenson, O Fadiran, A R Fazely, A Fedynitch, J Feintzeig, J Felde, T Feusels, K Filimonov, C Finley, T Fischer-Wasels, S Flis, A Franckowiak, K Frantzen, T Fuchs, T K Gaisser, R Gaior, J Gallagher, L Gerhardt, D Gier, L Gladstone, T Glüsenkamp, A Goldschmidt, G Golup, J G Gonzalez, J A Goodman, D Góra, D Grant, P Gretskov, J C Groh, A Groß, C Ha, C Haack, A Haj Ismail, P Hallen, A Hallgren, F Halzen, K Hanson, D Hebecker, D Heereman, D Heinen, K Helbing, R Hellauer, D Hellwig, S Hickford, G C Hill, K D Hoffman, R Hoffmann, A Homeier, K Hoshina, F Huang, W Huelsnitz, P O Hulth, K Hultqvist, S Hussain, A Ishihara, E Jacobi, J Jacobsen, K Jagielski, G S Japaridze, K Jero, O Jlelati, M Jurkovic, B Kaminsky, A Kappes, T Karg, A Karle, M Kauer, A Keivani, J L Kelley, A Kheirandish, J Kiryluk, J Kläs, S R Klein, J H Köhne, G Kohnen, H Kolanoski, A Koob, L Köpke, C Kopper, S Kopper, D J Koskinen, M Kowalski, A Kriesten, K Krings, G Kroll, M Kroll, J Kunnen, N Kurahashi, T Kuwabara, M Labare, D T Larsen, M J Larson, M Lesiak-Bzdak, M Leuermann, J Leute, J Lünemann, J Madsen, G Maggi, R Maruyama, K Mase, H S Matis, R Maunu, F McNally, K Meagher, M Medici, A Meli, T Meures, S Miarecki, E Middell, E Middlemas, N Milke, J Miller, L Mohrmann, T Montaruli, R Morse, R Nahnhauer, U Naumann, H Niederhausen, S C Nowicki, D R Nygren, A Obertacke, S Odrowski, A Olivas, A Omairat, A O'Murchadha, T Palczewski, L Paul, Ö Penek, J A Pepper, C Pérez de Los Heros, C Pfendner, D Pieloth, E Pinat, J Posselt, P B Price, G T Przybylski, J Pütz, M Quinnan, L Rädel, M Rameez, K Rawlins, P Redl, I Rees, R Reimann, M Relich, E Resconi, W Rhode, M Richman, B Riedel, S Robertson, J P Rodrigues, M Rongen, C Rott, T Ruhe, B Ruzybayev, D Ryckbosch, S M Saba, H-G Sander, J Sandroos, M Santander, S Sarkar, K Schatto, F Scheriau, T Schmidt, M Schmitz, S Schoenen, S Schöneberg, A Schönwald, A Schukraft, L Schulte, O Schulz, D Seckel, Y Sestayo, S Seunarine, R Shanidze, M W E Smith, D Soldin, G M Spiczak, C Spiering, M Stamatikos, T Stanev, N A Stanisha, A Stasik, T Stezelberger, R G Stokstad, A Stößl, E A Strahler, R Ström, N L Strotjohann, G W Sullivan, H Taavola, I Taboada, A Tamburro, A Tepe, S Ter-Antonyan, A Terliuk, G Tešić, S Tilav, P A Toale, M N Tobin, D Tosi, M Tselengidou, E Unger, M Usner, S Vallecorsa, N van Eijndhoven, J Vandenbroucke, J van Santen, M Vehring, M Voge, M Vraeghe, C Walck, M Wallraff, Ch Weaver, M Wellons, C Wendt, S Westerhoff, B J Whelan, N Whitehorn, C Wichary, K Wiebe, C H Wiebusch, D R Williams, H Wissing, M Wolf, T R Wood, K Woschnagg, D L Xu, X W Xu, J P Yanez, G Yodh, S Yoshida, P Zarzhitsky, J Ziemann, S Zierke, M Zoll, K Morik
We present the development and application of a generic analysis scheme for the measurement of neutrino spectra with the IceCube detector. This scheme is based on regularized unfolding, preceded by an event selection which uses a Minimum Redundancy Maximum Relevance algorithm to select the relevant variables and a random forest for the classification of events. The analysis has been developed using IceCube data from the 59-string configuration of the detector. 27,771 neutrino candidates were detected in 346 days of livetime...
2015: European Physical Journal. C, Particles and Fields
https://www.readbyqxmd.com/read/25978221/flavor-ratio-of-astrophysical-neutrinos-above-35%C3%A2-tev-in-icecube
#16
M G Aartsen, M Ackermann, J Adams, J A Aguilar, M Ahlers, M Ahrens, D Altmann, T Anderson, C Arguelles, T C Arlen, J Auffenberg, X Bai, S W Barwick, V Baum, R Bay, J J Beatty, J Becker Tjus, K-H Becker, S BenZvi, P Berghaus, D Berley, E Bernardini, A Bernhard, D Z Besson, G Binder, D Bindig, M Bissok, E Blaufuss, J Blumenthal, D J Boersma, C Bohm, F Bos, D Bose, S Böser, O Botner, L Brayeur, H-P Bretz, A M Brown, N Buzinsky, J Casey, M Casier, E Cheung, D Chirkin, A Christov, B Christy, K Clark, L Classen, F Clevermann, S Coenders, D F Cowen, A H Cruz Silva, J Daughhetee, J C Davis, M Day, J P A M de André, C De Clercq, H Dembinski, S De Ridder, P Desiati, K D de Vries, M de With, T DeYoung, J C Díaz-Vélez, J P Dumm, M Dunkman, R Eagan, B Eberhardt, T Ehrhardt, B Eichmann, J Eisch, S Euler, P A Evenson, O Fadiran, A R Fazely, A Fedynitch, J Feintzeig, J Felde, K Filimonov, C Finley, T Fischer-Wasels, S Flis, K Frantzen, T Fuchs, T K Gaisser, R Gaior, J Gallagher, L Gerhardt, D Gier, L Gladstone, T Glüsenkamp, A Goldschmidt, G Golup, J G Gonzalez, J A Goodman, D Góra, D Grant, P Gretskov, J C Groh, A Groß, C Ha, C Haack, A Haj Ismail, P Hallen, A Hallgren, F Halzen, K Hanson, D Hebecker, D Heereman, D Heinen, K Helbing, R Hellauer, D Hellwig, S Hickford, G C Hill, K D Hoffman, R Hoffmann, A Homeier, K Hoshina, F Huang, W Huelsnitz, P O Hulth, K Hultqvist, A Ishihara, E Jacobi, J Jacobsen, G S Japaridze, K Jero, M Jurkovic, B Kaminsky, A Kappes, T Karg, A Karle, M Kauer, A Keivani, J L Kelley, A Kheirandish, J Kiryluk, J Kläs, S R Klein, J-H Köhne, G Kohnen, H Kolanoski, A Koob, L Köpke, C Kopper, S Kopper, D J Koskinen, M Kowalski, A Kriesten, K Krings, G Kroll, M Kroll, J Kunnen, N Kurahashi, T Kuwabara, M Labare, J L Lanfranchi, D T Larsen, M J Larson, M Lesiak-Bzdak, M Leuermann, J Lünemann, J Madsen, G Maggi, R Maruyama, K Mase, H S Matis, R Maunu, F McNally, K Meagher, M Medici, A Meli, T Meures, S Miarecki, E Middell, E Middlemas, N Milke, J Miller, L Mohrmann, T Montaruli, R Morse, R Nahnhauer, U Naumann, H Niederhausen, S C Nowicki, D R Nygren, A Obertacke, A Olivas, A Omairat, A O'Murchadha, T Palczewski, L Paul, Ö Penek, J A Pepper, C Pérez de los Heros, C Pfendner, D Pieloth, E Pinat, J Posselt, P B Price, G T Przybylski, J Pütz, M Quinnan, L Rädel, M Rameez, K Rawlins, P Redl, I Rees, R Reimann, M Relich, E Resconi, W Rhode, M Richman, B Riedel, S Robertson, J P Rodrigues, M Rongen, C Rott, T Ruhe, B Ruzybayev, D Ryckbosch, S M Saba, H-G Sander, J Sandroos, M Santander, S Sarkar, K Schatto, F Scheriau, T Schmidt, M Schmitz, S Schoenen, S Schöneberg, A Schönwald, A Schukraft, L Schulte, O Schulz, D Seckel, Y Sestayo, S Seunarine, R Shanidze, M W E Smith, D Soldin, G M Spiczak, C Spiering, M Stamatikos, T Stanev, N A Stanisha, A Stasik, T Stezelberger, R G Stokstad, A Stößl, E A Strahler, R Ström, N L Strotjohann, G W Sullivan, H Taavola, I Taboada, A Tamburro, S Ter-Antonyan, A Terliuk, G Tešić, S Tilav, P A Toale, M N Tobin, D Tosi, M Tselengidou, E Unger, M Usner, S Vallecorsa, N van Eijndhoven, J Vandenbroucke, J van Santen, S Vanheule, M Vehring, M Voge, M Vraeghe, C Walck, M Wallraff, Ch Weaver, M Wellons, C Wendt, S Westerhoff, B J Whelan, N Whitehorn, C Wichary, K Wiebe, C H Wiebusch, D R Williams, H Wissing, M Wolf, T R Wood, K Woschnagg, D L Xu, X W Xu, Y Xu, J P Yanez, G Yodh, S Yoshida, P Zarzhitsky, J Ziemann, M Zoll
A diffuse flux of astrophysical neutrinos above 100 TeV has been observed at the IceCube Neutrino Observatory. Here we extend this analysis to probe the astrophysical flux down to 35 TeV and analyze its flavor composition by classifying events as showers or tracks. Taking advantage of lower atmospheric backgrounds for showerlike events, we obtain a shower-biased sample containing 129 showers and 8 tracks collected in three years from 2010 to 2013. We demonstrate consistency with the (fe:fμ:fτ)⊕≈(1:1:1)⊕ flavor ratio at Earth commonly expected from the averaged oscillations of neutrinos produced by pion decay in distant astrophysical sources...
May 1, 2015: Physical Review Letters
https://www.readbyqxmd.com/read/25751680/-indications-and-concept-of-follow-up-care-of-home-monitoring-for-premature-and-risk-infants
#17
K M Förster, S Immler, M Ensslen, A Flemmer, A Schulze, M von Poblotzki, O Genzel-Boroviczény, F Heinen, A Hilgendorff
The pros and cons of home monitoring especially for premature infants with continuing apneic episodes and/or chronic lung disease are an ongoing discussion. The controversy spans socio-economic requirements, medical indication as well as patient and family needs. Here, the costs of home monitoring and follow-up care on the one hand and longer hospitalization times on the other need to be considered. This article aims to create a basis for this discussion by summarizing current evidence for the indications and considerations for differential diagnoses while also outlining the established follow-up program for these patients at the Dr...
March 2015: Klinische Pädiatrie
https://www.readbyqxmd.com/read/25681941/short-time-diffusion-in-concentrated-bidisperse-hard-sphere-suspensions
#18
Mu Wang, Marco Heinen, John F Brady
Diffusion in bidisperse Brownian hard-sphere suspensions is studied by Stokesian Dynamics (SD) computer simulations and a semi-analytical theoretical scheme for colloidal short-time dynamics, based on Beenakker and Mazur's method [Physica A 120, 388-410 (1983); 126, 349-370 (1984)]. Two species of hard spheres are suspended in an overdamped viscous solvent that mediates the salient hydrodynamic interactions among all particles. In a comprehensive parameter scan that covers various packing fractions and suspension compositions, we employ numerically accurate SD simulations to compute the initial diffusive relaxation of density modulations at the Brownian time scale, quantified by the partial hydrodynamic functions...
February 14, 2015: Journal of Chemical Physics
https://www.readbyqxmd.com/read/25596902/alterations-in-the-trapezius-muscle-in-young-patients-with-migraine-a-pilot-case-series-with-mri
#19
M N Landgraf, B Ertl-Wagner, I K Koerte, J Thienel, T Langhagen, A Straube, R von Kries, P Reilich, A Pomschar, F Heinen
BACKGROUND/PURPOSE: Migraine is frequent in young adults and adolescents and often associated with neck muscle tension and pain. Common pathophysiological pathways, such as reciprocal cervico-trigeminal activation, are assumed. Tense areas within the neck muscles can be clinically observed many patients with migraine. The aim of this pilot case study was to visualize these tense areas via magnet resonance imaging (MRI). METHODS: Three young patients with migraine were examined by an experienced investigator...
May 2015: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/25519769/which-frail-older-patients-use-online-health-communities-and-why-a-mixed-methods-process-evaluation-of-use-of-the-health-and-welfare-portal
#20
Peter Makai, Marieke Perry, Sarah H M Robben, Henk Schers, Maud Heinen, Marcel G M Olde Rikkert, René J F Melis
BACKGROUND: Frail older people often receive fragmented care from multiple providers. According to the literature, there is an urgent need for coordination of care. Online and eHealth tools are increasingly used to improve coordination. However, there are significant barriers to their implementation in frail older people. OBJECTIVE: Our aim was to (1) evaluate differences in use of a personal online health community (POHC) for frail older people in relation to personal characteristics, and (2) explore barriers and facilitators for use as experienced by older people and their informal caregivers, using the case of the Health and Welfare Information Portal (ZWIP)...
2014: Journal of Medical Internet Research
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