Read by QxMD icon Read

Heinen F

S M G Zwakhalen, J P H Hamers, S F Metzelthin, R Ettema, M Heinen, J M De Man-Van Ginkel, G Huisman-De Waal, H Vermeulen, M J Schuurmans
AIMS: The aim of this paper is to describe and discuss the 'Basic Care Revisited' (BCR) research programme, a collaborative initiative that contributes to evidence-based basic nursing care and raises awareness about the importance of basic nursing care activities. BACKGROUND: While basic nursing care serves nearly all people at some point in their lifetime, it is poorly informed by evidence. There is a need to prioritize and evaluate basic nursing care activities to improve patient outcomes and improve the quality of care...
February 4, 2018: Journal of Clinical Nursing
Stefan G H Heinen, Daniel A F van den Heuvel, Wouter Huberts, Sanne W de Boer, Frans N van de Vosse, Tammo Delhaas, Jean-Paul P M de Vries
BACKGROUND: Currently, the decision to treat iliac artery stenoses is mainly based on visual inspection of digital subtraction angiographies. Intra-arterial pressure measurements can provide clinicians with accurate hemodynamic information. However, pressure measurements are rarely performed because of their invasiveness and the time required. Therefore, the aim of the study was to test the feasibility of a computational model that can predict translesional pressure gradients across iliac artery stenoses on the basis of imaging data only...
December 23, 2017: Journal of the American Heart Association
P R Heinen, A Bauermeister, L F Ribeiro, J M Messias, P Z Almeida, L A B Moraes, C G Vargas-Rechia, A H C de Oliveira, R J Ward, E X F Filho, M K Kadowaki, J A Jorge, M L T M Polizeli
The present study describes the one-step purification and biochemical characterization of an endo-1,4-β-xylanase from Aspergillus tamarii Kita. Extracellular xylanase was purified to homogeneity 7.43-fold through CM-cellulose. Enzyme molecular weight and pI were estimated to be 19.5kDa and 8.5, respectively. The highest activity of the xylanase was obtained at 60°C and it was active over a broad pH range (4.0-9.0), with maximal activity at pH 5.5. The enzyme was thermostable at 50°C, retaining more than 70% of its initial activity for 480min...
March 2018: International Journal of Biological Macromolecules
L Gerstl, M V Bonfert, T Nicolai, M Dieterich, C Adamczyk, F Heinen, M Olivieri, M Steinlin
Childhood arterial ischemic stroke differs in essential aspects from adult stroke. It is rare, often relatively unknown among laypersons and physicians and the wide variety of age-specific differential diagnoses (stroke mimics) as well as less established care structures often lead to a considerable delay in the diagnosis of stroke. The possible treatment options in childhood are mostly off-label. Experiences in well-established acute treatment modalities in adult stroke, such as thrombolysis and mechanical thrombectomy are therefore limited in children and only based on case reports and case series...
December 2017: Der Nervenarzt
M N Landgraf, H König, I Hannibal, T Langhagen, M V Bonfert, B Klose, B Rahmsdorf, R M Giese, A Straube, R von Kries, L Albers, F Ebinger, B Ertl-Wagner, B Kammer, I Körte, N Sollmann, S Krieg, F Heinen
Migraine as primary headache is a life-long disease which is relevant for the quality of life and is based on complex genetics. It often starts in childhood with symptoms typical for the specific age. These show different nuances compared to the migraine symptoms in adults, for example, regarding (bilateral/unilateral) localization of the acute migraine headache. Only over the course of years-during adolescence and young adulthood-do the more specific symptoms as defined by the International Classification of Headache Disorders (ICHD 3 beta) develop...
December 2017: Der Nervenarzt
M N Landgraf, J T Biebl, T Langhagen, I Hannibal, T Eggert, K Vill, L Gerstl, L Albers, R von Kries, A Straube, F Heinen
BACKGROUND: The objective was to evaluate a supposed clinical interdependency of myofascial trigger points and migraine in children. Such interdependency would support an interaction of spinal and trigeminal afferences in the trigemino-cervical complex as a contributing factor in migraine. METHODS: Children ≤18 years with the confirmed diagnosis of migraine were prospectively investigated. Comprehensive data on medical history, clinical neurological and psychological status were gathered...
February 2018: European Journal of Pain: EJP
F Heinen
No abstract text is available yet for this article.
December 2017: Der Nervenarzt
Sanne K Meles, David Vadasz, Remco J Renken, Elisabeth Sittig-Wiegand, Geert Mayer, Candan Depboylu, Kathrin Reetz, Sebastiaan Overeem, Angelique Pijpers, Fransje E Reesink, Teus van Laar, Lisette Heinen, Laura K Teune, Helmut Höffken, Marcus Luster, Karl Kesper, Sofie M Adriaanse, Jan Booij, Klaus L Leenders, Wolfgang H Oertel
BACKGROUND: Idiopathic REM sleep behavior disorder is a prodromal stage of Parkinson's disease and dementia with Lewy bodies. Hyposmia, reduced dopamine transporter binding, and expression of the brain metabolic PD-related pattern were each associated with increased risk of conversion to PD. The objective of this study was to study the relationship between the PD-related pattern, dopamine transporter binding, and olfaction in idiopathic REM sleep behavior disorder. METHODS: In this cross-sectional study, 21 idiopathic REM sleep behavior disorder subjects underwent 18 F-fluorodeoxyglucose PET, dopamine transporter imaging, and olfactory testing...
October 2017: Movement Disorders: Official Journal of the Movement Disorder Society
S W de Boer, Sgh Heinen, Daf van den Heuvel, F N van de Vosse, Jppm de Vries
Purpose The goal of the study was to review current literature regarding the diagnosis of equivocal (50-70%) iliofemoral artery stenosis and compare these findings with the daily practice of an international panel of endovascular experts. Methods The Medline Database was searched for relevant publications, and an electronic survey was sent to experts in the field covering the following topics: definition of an equivocal iliofemoral artery stenosis, angiographic visualization and investigation protocols of an equivocal stenosis, intra-arterial pressure measurements, and definition of hemodynamic significance of an equivocal iliofemoral artery stenosis using a physiologic measure...
December 2017: Vascular
J C van den Noort, L Bar-On, E Aertbeliën, M Bonikowski, S M Braendvik, E W Broström, A I Buizer, J H Burridge, A van Campenhout, B Dan, J F Fleuren, S Grunt, F Heinen, H L Horemans, C Jansen, A Kranzl, B K Krautwurst, M van der Krogt, S Lerma Lara, C M Lidbeck, J-P Lin, I Martinez, C Meskers, D Metaxiotis, G Molenaers, D A Patikas, O Rémy-Néris, K Roeleveld, A P Shortland, J Sikkens, L Sloot, R J Vermeulen, C Wimmer, A S Schröder, S Schless, J G Becher, K Desloovere, J Harlaar
BACKGROUND AND PURPOSE: To support clinical decision-making in central neurological disorders, a physical examination is used to assess responses to passive muscle stretch. However, what exactly is being assessed is expressed and interpreted in different ways. A clear diagnostic framework is lacking. Therefore, the aim was to arrive at unambiguous terminology about the concepts and measurement around pathophysiological neuromuscular response to passive muscle stretch. METHODS: During two consensus meetings, 37 experts from 12 European countries filled online questionnaires based on a Delphi approach, followed by plenary discussion after rounds...
July 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
C Brei, L Stecher, S Brunner, R Ensenauer, F Heinen, P D Wagner, J Hermsdörfer, H Hauner
BACKGROUND/OBJECTIVES: Evidence regarding the effect of n-3 long-chain polyunsaturated fatty acid (LCPUFA) supplementation during pregnancy on offspring's neurodevelopment is not conclusive. SUBJECTS/METHODS: In this analysis, the effect of a reduced n-6:n-3 LCPUFA ratio in the diet of pregnant/lactating women (1.2 g n-3 LCPUFA together with an arachidonic acid (AA)-balanced diet between 15th wk of gestation-4 months postpartum vs control diet) on child neurodevelopment at 4 and 5 years of age was assessed...
September 2017: European Journal of Clinical Nutrition
Seline R Goudeketting, Stefan G H Heinen, Çağdaş Ünlü, Daniel A F van den Heuvel, Jean-Paul P M de Vries, Marco J van Strijen, Anna M Sailer
PURPOSE: To systematically review and meta-analyze the added value of 3-dimensional (3D) image fusion technology in endovascular aortic repair for its potential to reduce contrast media volume, radiation dose, procedure time, and fluoroscopy time. METHODS: Electronic databases were systematically searched for studies published between January 2010 and March 2016 that included a control group describing 3D fusion imaging in endovascular aortic procedures. Two independent reviewers assessed the methodological quality of the included studies and extracted data on iodinated contrast volume, radiation dose, procedure time, and fluoroscopy time...
May 1, 2017: Journal of Endovascular Therapy
Gurkan Mollaoglu, Matthew R Guthrie, Stefanie Böhm, Johannes Brägelmann, Ismail Can, Paul M Ballieu, Annika Marx, Julie George, Christine Heinen, Milind D Chalishazar, Haixia Cheng, Abbie S Ireland, Kendall E Denning, Anandaroop Mukhopadhyay, Jeffery M Vahrenkamp, Kristofer C Berrett, Timothy L Mosbruger, Jun Wang, Jessica L Kohan, Mohamed E Salama, Benjamin L Witt, Martin Peifer, Roman K Thomas, Jason Gertz, Jane E Johnson, Adi F Gazdar, Robert J Wechsler-Reya, Martin L Sos, Trudy G Oliver
Loss of the tumor suppressors RB1 and TP53 and MYC amplification are frequent oncogenic events in small cell lung cancer (SCLC). We show that Myc expression cooperates with Rb1 and Trp53 loss in the mouse lung to promote aggressive, highly metastatic tumors, that are initially sensitive to chemotherapy followed by relapse, similar to human SCLC. Importantly, MYC drives a neuroendocrine-low "variant" subset of SCLC with high NEUROD1 expression corresponding to transcriptional profiles of human SCLC...
February 13, 2017: Cancer Cell
F Gunkel, S Hoffmann-Eifert, R A Heinen, D V Christensen, Y Z Chen, N Pryds, R Waser, R Dittmann
The formation mechanism of 2-dimensional electron gases (2DEGs) at heterointerfaces between nominally insulating oxides is addressed with a thermodynamical approach. We provide a comprehensive analysis of the thermodynamic ground states of various 2DEG systems directly probed in high temperature equilibrium conductivity measurements. We unambiguously identify two distinct classes of oxide heterostructures: For epitaxial perovskite/perovskite heterointerfaces (LaAlO3/SrTiO3, NdGaO3/SrTiO3, and (La,Sr)(Al,Ta)O3/SrTiO3), we find the 2DEG formation being based on charge transfer into the interface, stabilized by the electric field in the space charge region...
December 19, 2016: ACS Applied Materials & Interfaces
G B Whitworth, B C Misaghi, D M Rosenthal, E A Mills, D J Heinen, A H Watson, C W Ives, S H Ali, K Bezold, N Marsh-Armstrong, F L Watson
Unlike adult mammals, adult frogs regrow their optic nerve following a crush injury, making Xenopus laevis a compelling model for studying the molecular mechanisms that underlie neuronal regeneration. Using Translational Ribosome Affinity Purification (TRAP), a method to isolate ribosome-associated mRNAs from a target cell population, we have generated a transcriptional profile by RNA-Seq for retinal ganglion cells (RGC) during the period of recovery following an optic nerve injury. Based on bioinformatic analysis using the Xenopus laevis 9...
June 15, 2017: Developmental Biology
M Keurhorst, M Heinen, J Colom, C Linderoth, U Müssener, K Okulicz-Kozaryn, J Palacio-Vieira, L Segura, F Silfversparre, L Słodownik, E Sorribes, M Laurant, M Wensing
BACKGROUND: Screening and brief interventions (SBI) in primary healthcare are cost-effective in risky drinkers, yet they are not offered to all eligible patients. This qualitative study aimed to provide more insight into the factors and mechanisms of why, how, for whom and under what circumstances implementation strategies work or do not work in increasing SBI. METHODS: Semi-structured interviews were conducted between February and July 2014 with 40 GPs and 28 nurses in Catalonia, the Netherlands, Poland, and Sweden...
June 7, 2016: BMC Family Practice
S D Joustra, C A Heinen, N Schoenmakers, M Bonomi, B E P B Ballieux, M-O Turgeon, D J Bernard, E Fliers, A S P van Trotsenburg, M Losekoot, L Persani, J M Wit, N R Biermasz, A M Pereira, W Oostdijk
Clinical and biochemical characteristics of 69 male patients and 56 female IGSF1 mutation carriers were collected, providing recommendations for mutational analysis, endocrine work-up, and long-term care.
April 2016: Journal of Clinical Endocrinology and Metabolism
Marc Manley, Donald B Ardell, Judd R Allen, LuAnn Heinen
No abstract text is available yet for this article.
November 2015: American Journal of Health Promotion: AJHP
Marco Heinen, Simon K Schnyder, John F Brady, Hartmut Löwen
We introduce fractal liquids by generalizing classical liquids of integer dimensions d=1,2,3 to a noninteger dimension dl. The particles composing the liquid are fractal objects and their configuration space is also fractal, with the same dimension. Realizations of our generic model system include microphase separated binary liquids in porous media, and highly branched liquid droplets confined to a fractal polymer backbone in a gel. Here, we study the thermodynamics and pair correlations of fractal liquids by computer simulation and semianalytical statistical mechanics...
August 28, 2015: Physical Review Letters
A Herminghaus, F Barthel, A Heinen, C Beck, C Vollmer, I Bauer, A Weidinger, A V Kozlov, O Picker
Mitochondrial dysfunction is assumed to be an important contributor to multi organ dysfunction syndrome. Here, the effects of varying degrees of sepsis on hepatic mitochondrial function were investigated. Moderate or more severe sepsis was induced in rats using a colon ascendens stent peritonitis (CASP)-model (16 G and 14 G stent respectively). Respiratory control ratio (RCR) was significantly higher in the 16 G-group and unchanged in the 14 G-group compared with healthy controls. The ADP/O ratio was similar in all groups...
September 2015: Mitochondrion
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"