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atypical plexus choroid

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https://www.readbyqxmd.com/read/28291373/neoadjuvant-chemotherapy-for-atypical-teratoid-rhabdoid-tumors-case-report
#1
Meena Thatikunta, Ian Mutchnick, Jennifer Elster, Matthew P Thompson, Michael A Huang, Aaron C Spalding, Thomas Moriarty
Atypical teratoid rhabdoid tumors (ATRTs) are a rare pediatric brain tumor with high mortality rate. Several large series have reported achieving gross-total resection (GTR) in less than 50% of patients due to the lesions' large size, vascularity, and limited blood volume in young patients. While neoadjuvant chemotherapy for choroid plexus carcinomas in pediatric patients has become widely accepted, it has not been used as widely for other pediatric brain tumors. To the best of the authors' knowledge, there are only 3 published cases of neoadjuvant chemotherapy for ATRTs...
March 10, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28290001/choroid-plexus-tumors-in-adult-and-pediatric-populations-the-cleveland-clinic-and-university-hospitals-experience
#2
Michal Bahar, Hasan Hashem, Tanya Tekautz, Sarah Worley, Anne Tang, Peter de Blank, Johannes Wolff
Choroid plexus tumors (CPT) are rare neoplasms accounting for 1-4% of all pediatric brain tumors. They are divided into choroid plexus papilloma (CPP), atypical choroid plexus papilloma (APP) and choroid plexus carcinoma (CPC). CPTs are known to primarily affect children less than 2 years of age. Gross total resection is the most important predictor of survival especially in CPC. Although small case series have been published, limited clinical data are available to describe treatment and outcome of CPTs. More clinical data would be necessary to complete the picture, particularly in populations that are not age limited...
March 13, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28180935/clinicopathological-features-and-microsurgical-outcomes-for-giant-pediatric-intracranial-tumor-in-60-consecutive-cases
#3
Ailing Guo, Vigneyshwar Suresh, Xianzhi Liu, Fuyou Guo
PURPOSE: Giant pediatric intracranial tumor (GPIT) remains to be a challenging disease with high morbidity and mortality. METHODS: The clinical data of 60 patients under 18 years of age operated on with GPIT (≥5 cm in diameter) were retrospectively analyzed. RESULTS: Gross total resection was achieved in 46 cases (77%) and subtotal resection was obtained in 14 cases (23%). Ninety percent (47/52) of the cases with obstructive hydrocephalus were resolved remarkably and only 10% (5/52) of the patients needed a ventriculoperitoneal shunt after tumor resection...
February 8, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28062214/in-utero-exposure-to-atypical-antipsychotic-drug-risperidone-effects-on-fetal-neurotoxicity-in-hippocampal-region-and-cognitive-impairment-in-rat-offspring
#4
K P Singh, Manoj Kr Singh
Clinical studies indicate that about one-third of pregnant women with psychotic symptoms are exposed to either typical or atypical antipsychotic drugs (APDs). Reports on prenatal subject/model are lacking hence, the present study was undertaken to investigate the effect of prenatal exposure to risperidone (RIS) on the fetal hippocampus, and their related functional changes in young rat offspring. In this study, pregnant Wistar rats were exposed to equivalent therapeutic doses of RIS at 0.8mg/kg, 1.0mg/kg, and 2...
April 3, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28025236/otx2-defines-a-subgroup-of-atypical-teratoid-rhabdoid-tumors-with-close-relationship-to-choroid-plexus-tumors
#5
Anna Sophia Japp, Ludger Klein-Hitpass, Dorota Denkhaus, Torsten Pietsch
Atypical teratoid rhabdoid tumors (ATRT) are highly malignant brain tumors of early childhood that have been regarded as a homogenous entity characterized by inactivation of the SMARCB1/INI1 or SMARCA4/BRG1 genes as the only characteristic alteration. Recent studies suggest that similar to other embryonal tumors ATRT can also be divided into subgroups based on their mRNA or methylation profiles. Using microarray-based expression analysis of 12 patient ATRT specimens we demonstrated the existence of 2 subgroups of ATRT...
December 26, 2016: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/27506402/choroid-plexus-papillomas-of-the-cerebellopontine-angle
#6
Wei Luo, Hai Liu, Jiaxin Li, Jun Yang, Yulun Xu
OBJECTIVE: Choroid plexus papillomas (CPPs) of the cerebellopontine angle (CPA) are extremely rare. We present a series of 21 cases operated on in the last 7 years at our institution. METHODS: During the period from January 2008 to October 2015, we encountered 102 histologically established cases of CPPs, of which 21 were located in the CPA region. Clinical profiles, radiologic features, surgical procedures, intraoperative findings, and outcomes were extracted from the patient records and neuroimaging data...
November 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27442759/metachronous-type-i-pleuropulmonary-blastoma-and-atypical-choroid-plexus-papilloma-in-a-young-child
#7
David J Liu, Renee Perrier, Xing-Chang Wei, Jeffrey T Joseph, Douglas Strother
Pleuropulmonary blastoma (PPB) is a rare childhood tumor, often associated with germline DICER1 mutations and a risk for development of other benign and malignant tumors, a constellation termed DICER1 syndrome. A 1-year-old male was diagnosed with Type I PPB and screened regularly thereafter for detection of intrathoracic and intraabdominal disease. Ten months after diagnosis of PPB, he presented with headaches and vomiting. He was diagnosed with atypical choroid plexus papilloma, a lesion not previously reported with PPB...
July 21, 2016: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/27372242/disseminated-choroid-plexus-papillomas-in-adults-a-case-series-and-review-of-the-literature
#8
Marwah M Abdulkader, Nassir H Mansour, Jamie J Van Gompel, Gregory A Bosh, Edward J Dropcho, Jose M Bonnin, Aaron A Cohen-Gadol
Choroid plexus papillomas (CPPs) are uncommon, usually intraventricular, low-grade tumors, accounting for less than 1% of all intracranial neoplasms and 2-4% of brain tumors in children. Dissemination of CPPs to multiple levels of the neuraxis has been seldom observed. Thus far, only 26 adult patients have been reported in the English language literature. With some exceptions, disseminated CPPs have been observed in adults and involved multiple sites along the cerebrospinal fluid pathways. Occasionally, intraparenchymal extension has been documented, and secondary involvement of the suprasellar region has been reported in only five patients...
October 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27323560/morphological-pattern-and-frequency-of-central-nervous-system-tumours-in-children
#9
Fatima Bilqees, Khaleeq Samina, Tahir Mohammad, Khaleeq-uz-Zamaan
BACKGROUND: Recent studies, including a comprehensive study by National Cancer Institute, have shown that a significant increase in the incidence of childhood brain tumours makes them the most common paediatric tumour. The objectives of this study were to determine the frequency of central nervous system tumours in paediatric age group (0-12 years), and to segregate various morphologic types according to WHO classification. METHODS: The study included consecutive cases of central nervous system tumours diagnosed in children in the histopathology department at Federal Government Polyclinic, PGMI, Islamabad, during a period of 4...
January 2016: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/26899566/use-of-dynamic-18-f-fluorodeoxyglucose-positron-emission-tomography-to-investigate-choroid-plexus-function-in-alzheimer-s-disease
#10
Joël Daouk, Roger Bouzerar, Bader Chaarani, Jadwiga Zmudka, Marc-Etienne Meyer, Olivier Balédent
Choroid plexuses (CPs) are structures involved in CSF production and cerebral regulation and present atypical glucose metabolism. In addition, CPs impairment may be related to Alzheimer disease (AD). In the present study, we present the first results pointing out glucose metabolism in the CP with dynamic fluorodeoxyglucose positron emission tomography (dynamic (18)F-FDG-PET). We studied 47 elderly adults who were classified into three classes: healthy subjects (HS), amnestic mild cognitive impairment (aMCI) and AD...
May 2016: Experimental Gerontology
https://www.readbyqxmd.com/read/26801774/rare-primary-central-nervous-system-tumors-encountered-in-pediatrics
#11
Kim Kramer
As part of the special issue on Pediatric Neuro-Oncology, this article will focus on 4 of the rarer tumors in this spectrum, including atypical teratoid rhabdoid tumors, embryonal tumors with multilayered rosettes, choroid plexus tumors, and pleomorphic xanthoastrocytoma. Incidence and current understanding of the molecular pathogenesis of these tumors are discussed, and avenues of therapy both current and prospective are explored.
October 2016: Journal of Child Neurology
https://www.readbyqxmd.com/read/26478476/choroid-plexus-tumors-experience-of-10-cases-with-special-references-to-adult-cases
#12
Manoj Bohara, Masashi Hirabaru, Shingo Fujio, Michiyo Higashi, Hajime Yonezawa, Prasanna Karki, Ryosuke Hanaya, Hirofumi Hirano, Hiroshi Tokimura, Kazunori Arita
Choroid plexus tumors (CPTs) are rare intraventricular neoplasms accounting for about 0.3-0.6% of all intracranial tumors. This retrospective study on CPTs presents clinico-pathological features and management strategies based on a 20-year single-institutional experience. This series included 10 consecutive patients with pathologically proven CPTs; 5 choroid plexus papillomas (CPPs), 3 atypical CPPs (ACPPs), and 2 choroid plexus carcinomas (CPCs). Their clinical, radiological, and histopathological features as well as management including follow-up studies were reviewed...
2015: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/26445956/microsurgical-treatment-of-atypical-choroid-plexus-papilloma-in-the-fourth-ventricle
#13
LETTER
Ermeng Ma, Jun Wang, Geifei Guan, Wei Wei, Yunjie Wang
No abstract text is available yet for this article.
September 2016: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/26209253/-choroid-plexus-tumours-in-childhood-experience-in-sant-joan-de-d%C3%A3-u-hospital
#14
Clara Maria Del Río-Pérez, Mariona Suñol-Capella, Ofelia Cruz-Martinez, Gemma Garcia-Fructuoso
Choroid plexus tumours are rare, with a peak incidence in the first two years of life. The most common location is the lateral ventricle in children, while in adults it is the fourth ventricle. The most common clinical manifestation is the signs and symptoms of intracranial hypertension. They are histologically classified as plexus papilloma, atypical plexus papilloma, and plexus carcinoma. A review is presented on choroid plexus tumours treated in the Hospital Sant Joan de Déu between 1980 and 2014. A total of 18 patients have been treated...
March 2016: Neurocirugía
https://www.readbyqxmd.com/read/25944396/clinicopathologic-study-of-endolymphatic-sac-tumor-elst-and-differential-diagnosis-of-papillary-tumors-located-at-the-cerebellopontine-angle
#15
Jiang Du, Junmei Wang, Yun Cui, Cuiping Zhang, Guilin Li, Jingyi Fang, Shenglin Yue, Li Xu
We investigated the clinicopathologic features and immunophenotypes of 10 cases of endolymphatic sac tumor (ELST) and compared them with other papillary tumors, including eight cases of choroid plexus papilloma (CPP), three cases of atypical choroid plexus papilloma (ACPP), two cases of papillary ependymoma (PE), three cases of papillary meningioma (PM) and two cases of metastatic carcinoma (MC) the at cerebellopontine angle (CPA). The age at onset of ELST ranged from 13 to 39 years. The male-to-female ratio was 1:1...
October 2015: Neuropathology: Official Journal of the Japanese Society of Neuropathology
https://www.readbyqxmd.com/read/25935663/pediatric-atypical-choroid-plexus-papilloma-reconsidered-increased-mitotic-activity-is-prognostic-only-in-older-children
#16
LETTER
Christian Thomas, Vincent Ruland, Uwe Kordes, Stefan Hartung, David Capper, Torsten Pietsch, Joachim Gerß, Johannes E A Wolff, Werner Paulus, Martin Hasselblatt
No abstract text is available yet for this article.
June 2015: Acta Neuropathologica
https://www.readbyqxmd.com/read/25863950/the-role-of-chemotherapy-and-surgical-removal-in-the-treatment-of-choroid-plexus-carcinomas-and-atypical-papillomas
#17
Annalisa Passariello, Maria Tufano, Pietro Spennato, Lucia Quaglietta, Antonio Verrico, Roberta Migliorati, Giuseppe Cinalli
INTRODUCTION: We performed a retrospective study on clinical assessment, tumor location, radiological imaging, histopathological characteristics, and therapeutic management of 7 patients affected by choroid plexus carcinoma (CPC) or atypical choroid plexus papilloma (ACPP) who have been observed in the last 12 years. METHODS: Four patients fulfilled the criteria for classification as ACPP and three cases as CPC. The median age of the patients at the diagnosis was 42 months (range 3-190 months)...
July 2015: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/25839397/delayed-diagnosis-of-enhancing-posterior-fossa-tumors-mimicking-the-tela-choroidea-of-the-fourth-ventricle
#18
Brandon C Gabel, Michael L Levy, John R Crawford
BACKGROUND: Posterior fossa brain tumors are common in children. Symptoms typically develop when the tumors have reached sufficient size to cause compression of adjacent neural structures or cause obstructive hydrocephalus. Many tumors in this region originate from the tela choroidea and choroid plexus of the fourth ventricle. Enhancement of the fourth ventricular tela choroidea and choroid plexus is uncommon in children, and when such enhancement is present, it may represent early tumor growth...
September 2015: World Neurosurgery
https://www.readbyqxmd.com/read/25816082/combined-rigid-and-flexible-endoscopy-for-tumors-in-the-posterior-third-ventricle
#19
Jonathan Roth, Shlomi Constantini
OBJECT: Tumors leading to occlusion of the sylvian aqueduct include those of pineal, thalamic, and tectal origins. These tumors cause obstructive hydrocephalus and thus necessitate a CSF diversion procedure such as an endoscopic third ventriculostomy (ETV), often coupled with an endoscopic biopsy (EBX). Lesions located posterior to the massa intermedia pose a technical challenge, as the use of a rigid endoscope for performing both an ETV and EBX is limited. The authors describe their experience using a combined rigid and flexible endoscopic procedure through a single bur hole for both procedures in patients with posterior third ventricular tumors...
June 2015: Journal of Neurosurgery
https://www.readbyqxmd.com/read/25724620/-choroid-plexus-tumour-treatment-at-hospital-infantil-ni%C3%A3-o-jes%C3%A3%C2%BAs-in-madrid-our-experience-over-the-last-three-decades
#20
Isabel Cuervo-Arango, Pedro Reimunde, Julio César Gutiérrez, Ana Aransay, Belén Rivero, Carlos Pérez, Marcelo Budke, Francisco Villarejo
OBJECTIVE: To review childhood patients with choroid plexus tumors (CPT) who underwent surgery at Hospital Infantil Niño Jesús of Madrid since January 1981 to September 2014. MATERIAL AND METHODS: Registered charts were analyzed based on the epidemiology, tumor grade, clinical profile, location, dissemination characteristics, therapy, prognosis and complications. RESULTS: Seventeen childhood patients were recorded with CPT. Cases were distributed so that 9 cases were choroid plexus-papilloma (CPP) (52...
September 2015: Neurocirugía
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