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https://www.readbyqxmd.com/read/27885615/the-white-mullet-mugil-curema-as-biological-indicator-to-assess-environmental-stress-in-tropical-coastal-lagoons
#1
Alejandra García-Gasca, Julián Ríos-Sicairos, Rubí Hernández-Cornejo, Isabel Cunha, Jesús N Gutiérrez, Héctor Plascencia-González, Luz María García de la Parra, Selene Abad-Rosales, Miguel Betancourt-Lozano
Several coastal lagoons and estuaries in Mexico receive untreated domestic and industrial discharges which contain complex mixtures of contaminants. In order to assess the effects of chemical contamination, we used the White mullet (Mugil curema) as biological indicator. We worked in two estuaries located in Northwest Mexico: Urias (highly polluted) and Teacapan (less polluted, therefore used as reference site). We measured several endpoints at different levels of biological organization: vitellogenin transcription in males as biomarker of estrogenic contamination, as well as reproductive, morphological (deformities), morphometric, and meristic parameters...
December 0: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/27867855/laparoscopic-approach-for-gonadectomy-in-pediatric-patients-with-intersex-disorders
#2
REVIEW
Andres Calvo, Maria Escolino, Alessandro Settimi, Agnese Roberti, Maria Grazia Caprio, Ciro Esposito
The birth of a child with a disorder of sex development (DSD) prompts a long-term management strategy that involves a myriad of professionals working with the family. There has been progress in diagnosis, surgical techniques and in understanding psychosocial issues related to this condition. However, since these kinds of disorders are rare and have many anatomical variations, individual care is necessary, especially regarding surgical management. Gonadectomy is indicated in a number of intersex disorders with a Y chromosome to reduce the associated risk of cancer...
October 2016: Translational pediatrics
https://www.readbyqxmd.com/read/27861489/characterizing-transcriptional-networks-in-male-rainbow-darter-etheostoma-caeruleum-that-regulate-testis-development-over-a-complete-reproductive-cycle
#3
Paulina A Bahamonde, Mark E McMaster, Mark R Servos, Christopher J Martyniuk, Kelly R Munkittrick
Intersex is a condition that has been associated with exposure to sewage effluents in male rainbow darter (Etheostoma caeruleum). To better understand changes in the transcriptome that are associated with intersex, we characterized annual changes in the testis transcriptome in wild, unexposed fish. Rainbow darter males were collected from the Grand River (Ontario, Canada) in May (spawning), August (post-spawning), October (recrudescence), January (developing) and March (pre-spawning). Histology was used to determine the proportion of spermatogenic cell types that were present during each period of testicular maturation...
2016: PloS One
https://www.readbyqxmd.com/read/27823735/long-term-health-issues-related-to-disorders-or-differences-in-sex-development-intersex
#4
REVIEW
Jennifer M Beale, Sarah M Creighton
DSD (Disorders or Differences in Sex Development) and Intersex are terms used to describe a diverse group of congenital conditions where the development of the reproductive system is different from what is usually expected. These conditions usually present at birth or adolescence and the health implications are wide ranging and often life-long. Given the complexity of many of the conditions, health care input when required should be provided by a multidisciplinary team who have appropriate expertise. Holistic care should include the consideration of the risk of cancer, prevention of osteoporosis, advice on hormones, sexual health and fertility options, and ongoing support in order to optimise quality of life and wellbeing...
December 2016: Maturitas
https://www.readbyqxmd.com/read/27810492/molecular-initiating-events-of-the-intersex-phenotype-low-dose-exposure-to-17%C3%AE-ethinylestradiol-rapidly-regulates-molecular-networks-associated-with-gonad-differentiation-in-the-adult-fathead-minnow-testis
#5
April Feswick, Jennifer R Loughery, Meghan A Isaacs, Kelly R Munkittrick, Christopher J Martyniuk
Intersex, or the presence of oocytes in the testes, has been documented in fish following exposure to wastewater effluent and estrogenic compounds. However, the molecular networks underlying the intersex condition are not completely known. To address this, we exposed male fathead minnows to a low, environmentally-relevant concentration of 17alpha-ethinylestradiol (EE2) (15ng/L) and measured the transcriptome response in the testis after 96h to identify early molecular initiating events that may proceed the intersex condition...
December 2016: Aquatic Toxicology
https://www.readbyqxmd.com/read/27785439/malignancy-in-disorders-of-sex-development
#6
REVIEW
Martin Kathrins, Thomas F Kolon
Disorders of sex development (DSD) represent a spectrum of conditions in which chromosomal, gonadal, or anatomic sex are atypical and affect 1 in 4,500-5,000 live births. The diagnosis of DSD raises concerns of tumor risk and treatment as well as future fertility preservation. We review the current understanding of the types of gonadal tumors that arise in DSD patients as well as possible markers and treatment. The goal is to inform the members of the DSD team (urologist, endocrinologist, geneticist, psychologist) of the latest findings regarding malignancy in DSD...
October 2016: Translational Andrology and Urology
https://www.readbyqxmd.com/read/27776151/an-assessment-of-the-spatial-and-temporal-variability-of-biological-responses-to-municipal-wastewater-effluent-in-rainbow-darter-etheostoma-caeruleum-collected-along-an-urban-gradient
#7
Meghan L M Fuzzen, Leslie M Bragg, Gerald R Tetreault, Paulina A Bahamonde, Rajiv N Tanna, Charles J Bennett, Mark E McMaster, Mark R Servos
Municipal wastewater effluent (MWWE) and its constituents, such as chemicals of emerging concern, pose a potential threat to the sustainability of fish populations by disrupting key endocrine functions in aquatic organisms. While studies have demonstrated changes in biological markers of exposure of aquatic organisms to groups of chemicals of emerging concern, the variability of these markers over time has not been sufficiently described in wild fish species. The aim of this study was to assess the spatial and temporal variability of biological markers in response to MWWE exposure and to test the consistency of these responses between seasons and among years...
2016: PloS One
https://www.readbyqxmd.com/read/27749265/occurrence-of-intersex-in-wild-freshwater-fish-in-slovenian-rivers-a-histological-evaluation
#8
Milka Vrecl, Vlasta Jenčič
The aim of this preliminary research was to establish if there are intersex occurrences in wild freshwater fish in Slovenian rivers and streams. In the first study we evaluated all fish species of both sexes obtained from the river Ljubljanica from its source to mouth. In the second study we focused on the rainbow trout (Oncorhynchus mykiss) and brown trout (Salmo trutta m. fario) males from 30 rivers and streams in different parts of Slovenia. The male gonads were histologically assessed for the presence of oocytes to determine the frequency and degree of intersex...
September 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/27685752/editorial-being-responsive-promoting-lgbti-health-and-well-being
#9
Calvin Moorley, Stephen Neville, Joy Johnson
No abstract text is available yet for this article.
September 29, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27677267/syndrome-related-stigma-in-the-general-social-environment-as-reported-by-women-with-classical-congenital-adrenal-hyperplasia
#10
Heino F L Meyer-Bahlburg, Jazmin A Reyes-Portillo, Jananne Khuri, Anke A Ehrhardt, Maria I New
Stigma defined as "undesired differentness" (Goffman, 1963) and subtyped as "experienced" or "enacted," "anticipated," and "internalized" has been documented for patients with diverse chronic diseases. However, no systematic data exist on the association of stigma with somatic intersexuality. The current report concerns women with classical congenital adrenal hyperplasia (CAH), the most prevalent intersex syndrome, and provides descriptive data on CAH-related stigma as experienced in the general social environment (excluding medical settings and romantic/sexual partners) during childhood, adolescence, and adulthood...
September 27, 2016: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/27660460/the-increasing-prevalence-in-intersex-variation-from-toxicological-dysregulation-in-fetal-reproductive-tissue-differentiation-and-development-by-endocrine-disrupting-chemicals
#11
REVIEW
Alisa L Rich, Laura M Phipps, Sweta Tiwari, Hemanth Rudraraju, Philip O Dokpesi
An increasing number of children are born with intersex variation (IV; ambiguous genitalia/hermaphrodite, pseudohermaphroditism, etc.). Evidence shows that endocrine-disrupting chemicals (EDCs) in the environment can cause reproductive variation through dysregulation of normal reproductive tissue differentiation, growth, and maturation if the fetus is exposed to EDCs during critical developmental times in utero. Animal studies support fish and reptile embryos exhibited IV and sex reversal when exposed to EDCs...
2016: Environmental Health Insights
https://www.readbyqxmd.com/read/27636351/narrating-sexual-identities-in-kenya-choice-value-and-visibility
#12
Jason Zingsheim, Dustin Bradley Goltz, Alexandra G Murphy, Teresa Mastin
This article examines the discursive construction of female same-sex sexual identities in Nairobi. We identify the discursive forces of "choice," devaluation, and invisibility as influential within Kenyan media representations of lesbian, gay, bisexual, transgender, and intersex citizens. Using creative focus groups and participant observation, we demonstrate how same-sex attracted women in Nairobi resist and rearticulate these discursive forces to assert their identity and agency as individuals and as a queer community...
September 16, 2016: Journal of Lesbian Studies
https://www.readbyqxmd.com/read/27613909/smoking-cessation-programs-for-lesbian-gay-bisexual-transgender-and-intersex-people-a-content-based-systematic-review
#13
Israel Berger, Julie Mooney-Somers
INTRODUCTION: Tobacco use among lesbian, gay, bisexual, and transgender (LGBT) people is double the general population. Limited evidence suggests high smoking rates among intersex people. Lesbian, gay, bisexual, transgender, and intersex (LGBTI) people are a priority population in Australian health policy, particularly mental health and ageing. Despite associations between smoking and non-communicable diseases relevant to ageing and mental health, LGBTI-targeted smoking cessation interventions in Australia have been limited to people living with HIV...
August 31, 2016: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/27611864/determining-the-optimal-developmental-stages-of-xenopus-laevis-for-initiating-exposures-to-chemicals-for-sensitively-detecting-their-feminizing-effects-on-gonadal-differentiation
#14
Yuan-Yuan Li, Juan Chen, Zhan-Fen Qin
Xenopus laevis is an important model for detecting feminizing effects of endocrine disrupting chemicals (EDCs) on amphibians because its genetic males can be induced to phenotypic females by estrogenic chemicals. It is crucial that chemical exposures begin at sensitive developmental stages for gonadal sex-reversal in X. laevis. To determine the optimal stages for initiating exposures, we investigated gonadal sex-reversal induced by low concentrations of 17α-ethinylestradiol (EE2) when exposures were initiated at different stages (3/4, 45/46, 48 and 50) until stage 58...
October 2016: Aquatic Toxicology
https://www.readbyqxmd.com/read/27593516/-homophobia-hurts-mourning-as-resistance-to-violence-in-south-africa
#15
Julie Moreau
Much has been written on the successful lesbian, gay, bisexual, transgender, and intersex movement in South Africa, and the resulting institutionalization of sexual minority rights. Comparatively less has been written about the forms of activism undertaken specifically by Black lesbians that are not oriented toward legal change. In this article, I assert the need to examine public demonstrations of mourning as an act of Black lesbian resistance to violence in South Africa. Based on in-depth interviews with members of Free Gender, a Black lesbian organization, I argue that members' conceptualizations of mourning as providing community support force a reconsideration of what it means to be human...
September 3, 2016: Journal of Lesbian Studies
https://www.readbyqxmd.com/read/27591376/gonado-histopathological-changes-intersex-and-endocrine-disruptor-responses-in-relation-to-contaminant-burden-in-tilapia-species-from-ogun-river-nigeria
#16
Oju R Ibor, Aina O Adeogun, Olusegun A Fagbohun, Augustine Arukwe
In the present study, we investigated the occurrence of intersex condition, histopathological changes in the gonad and endocrine disruptor biomarker responses in Tilapia species (Tilaipia guineensis, Sarotherodon galileaus and Oreochromis niloticus) along the Ogun River, Nigeria. The study sites covered a length of 320 km and a total of 1074 tilapias were collected from three sampling sites (Abeokuta, Isheri and Ikorodu) with different degrees of anthropogenic contamination. Samples were also collected from an upstream putative control site (Igboho) along the Ogun River...
December 2016: Chemosphere
https://www.readbyqxmd.com/read/27583788/foxl3-a-target-of-mir-9-stimulates-spermatogenesis-in-spermatogonia-during-natural-sex-change-in-monopterus-albus
#17
Yu Gao, Dan Jia, Qing Hu, Dapeng Li
Two foxl2 paralogs, foxl2 (also named foxl2a) and foxl3 (also named foxl2b) were considered as fish-specific duplicates. Both belong to the Forkhead box family of transcription factors, which play important roles in regulating reproduction involved in sexual differentiation and regulation of primordial germ cell and gonadal somatic cell development. We isolated the complete foxl3 cDNA from the rice field eel (Monopterus albus), which undergoes a natural female-to-male sex change via an intersex stage during its life cycle...
September 1, 2016: Endocrinology
https://www.readbyqxmd.com/read/27583571/endocrine-active-contaminants-in-aquatic-systems-and-intersex-in-common-sport-fishes
#18
Crystal S D Lee Pow, J Mac Law, Thomas J Kwak, W Gregory Cope, James A Rice, Seth W Kullman, D Derek Aday
Male fish are susceptible to developing intersex, a condition characterized by the presence of testicular oocytes. In the present study, the relationship between intersex and exposure to estrogenic endocrine active contaminants (EACs) was assessed for 2 genera of sport fish, Micropterus and Lepomis, at 20 riverine sites. Seasonal trends and relationships between EACs and intersex (prevalence and severity) were examined at varying putative sources of EACs throughout North Carolina, identified as 'point', 'non-point' and 'reference' sites...
September 1, 2016: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/27578341/the-human-rights-of-intersex-people-addressing-harmful-practices-and-rhetoric-of-change
#19
Morgan Carpenter
Intersex people and bodies have been considered incapable of integration into society. Medical interventions on often healthy bodies remain the norm, addressing perceived familial and cultural demands, despite concerns about necessity, outcomes, conduct and consent. A global and decentralised intersex movement pursues simple core goals: the rights to bodily autonomy and self-determination, and an end to stigmatisation. The international human rights system is responding with an array of new policy statements from human rights institutions and a handful of national governments recognising the rights of intersex people...
May 2016: Reproductive Health Matters
https://www.readbyqxmd.com/read/27543636/coming-out-in-class-challenges-and-benefits-of-active-learning-in-a-biology-classroom-for-lgbtqia-students
#20
Katelyn M Cooper, Sara E Brownell
As we transition our undergraduate biology classrooms from traditional lectures to active learning, the dynamics among students become more important. These dynamics can be influenced by student social identities. One social identity that has been unexamined in the context of undergraduate biology is the spectrum of lesbian, gay, bisexual, transgender, queer, intersex, and asexual (LGBTQIA) identities. In this exploratory interview study, we probed the experiences and perceptions of seven students who identify as part of the LGBTQIA community...
2016: CBE Life Sciences Education
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