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https://www.readbyqxmd.com/read/27895428/lymphovascular-invasion-in-more-than-one-quarter-of-small-rectal-neuroendocrine-tumors
#1
Mi Jung Kwon, Ho Suk Kang, Jae Seung Soh, Hyun Lim, Jong Hyeok Kim, Choong Kee Park, Hye-Rim Park, Eun Sook Nam
AIM: To identify the frequency, clinicopathological risk factors, and prognostic significance of lymphovascular invasion (LVI) in endoscopically resected small rectal neuroendocrine tumors (NETs). METHODS: Between June 2005 and December 2015, 104 cases of endoscopically resected small (≤ 1 cm) rectal NET specimens at Hallym University Sacred Heart Hospital in Korea were retrospectively evaluated. We compared the detected rate of LVI in small rectal NET specimens by two methods: hematoxylin and eosin (H&E) and ancillary immunohistochemical staining (D2-40 and Elastica van Gieson); in addition, LVI detection rate difference between endoscopic procedures were also evaluated...
November 14, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27874310/ancient-microrna-families-that-regulate-transcription-factors-are-preferentially-preserved-during-plant-radiation
#2
Tao Shi, Kun Wang, Pingfang Yang
Essential genes are usually less likely to be lost during evolution, whereas dispensable genes are lost more frequently. Integrating sacred lotus and other plant microRNA (miRNA) data, we found different ancient miRNA families that arose before eudicot radiation exhibit different evolutionary trajectories. Those ancient miRNA families with higher copy and target numbers, and older age are more likely to be retained in plant descendants and more conserved in (hairpin-structured) miRNA gene sequences. Interestingly, a large portion of the well conserved miRNA families in plant lineages can target transcription factors (TFs)...
November 22, 2016: Plant Signaling & Behavior
https://www.readbyqxmd.com/read/27874256/correlation-of-vitamin-d-levels-with-tear-film-stability-and-secretion-in-patients-with-dry-eye-syndrome
#3
Ki Won Jin, Jin Woo Ro, Young Joo Shin, Joon Young Hyon, Won Ryang Wee, Shin Goo Park
PURPOSE: To investigate tear film stability and secretion according to serum 25-hydroxyvitamin D3 [25(OH)D] levels in dry eye patients. METHODS: In this retrospective observational study, the medical charts of 92 patients who visited the Department of Ophthalmology at Hallym University Kangnam Sacred Heart Hospital from April to August 2015 were reviewed. Serum 25(OH)D levels were measured. Subjects were divided into three groups according to serum 25(OH)D levels: sufficient, inadequate or deficient group...
November 22, 2016: Acta Ophthalmologica
https://www.readbyqxmd.com/read/27873406/watch-scrubs-a-video-observational-study-of-workplace-based-learning-at-sacred-heart-hospital
#4
Eliot L Rees, Yashashwi Sinha, Benjamin Davies, Patrick J Quinn
CONTEXT: Workplace-based learning remains the cornerstone of clinical training. Teaching in the clinical environment promotes active engagement as trainees are required to combine their competencies (e.g. skills in history taking, examination and clinical reasoning) to determine an appropriate course of action. High-quality clinical teaching supports and scaffolds trainees' learning in clinical workplaces. OBJECTIVES: This study aimed to explore the quality of clinical teaching at a large teaching hospital...
December 2016: Medical Education
https://www.readbyqxmd.com/read/27863914/cultural-aspects-and-mythologies-surrounding-menstruation-and-abnormal-uterine-bleeding
#5
REVIEW
Delfin A Tan, Rohana Haththotuwa, Ian S Fraser
The objective of this chapter is to present an overview of how menstruation, a normal bodily function, was and is perceived in various ethnic groups and cultures in the world, from ancient mythology, historical, or traditional practices to contemporary belief systems. Mythical tales about menstruation abound in the legends and prehistory of ancient cultures. These tales characterize menstrual blood variously as sacred, a gift from the gods, or a punishment for sin, but it is almost always magical and powerful...
October 26, 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27862817/design-of-s-allylcysteine-in-situ-production-and-incorporation-based-on-a-novel-pyrrolysyl-trna-synthetase-variant
#6
Matthias P Exner, Tilmann Kuenzl, Tuyet Mai T To, Zhaofei Ouyang, Sergej Schwagerus, Michael G Hoesl, Christian P R Hackenberger, Marga C Lensen, Sven Panke, Nediljko Budisa
The noncanonical amino acid S-allyl cysteine (Sac) is one of the major compounds of garlic extract and exhibits a range of biological activities. It is also a small bioorthogonal alkene tag capable of undergoing controlled chemical modifications, such as photoinduced thiol-ene coupling or Pd-mediated deprotection. Its small size guarantees minimal interference with protein structure and function. Here, we report a simple protocol efficiently to couple in-situ semisynthetic biosynthesis of Sac and its incorporation into proteins in response to amber (UAG) stop codons...
November 14, 2016: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/27856779/treatment-of-neurosarcoidosis-a-comparative-study-of-methotrexate-and-mycophenolate-mofetil
#7
Samuel Bitoun, Diane Bouvry, Raphaël Borie, Mathieu Mahevas, Karim Sacre, Julien Haroche, Dimitri Psimaras, Corinne Pottier, Alexis Mathian, Miguel Hie, Du Le Thi Huong Boutin, Thomas Papo, Bertrand Godeau, Dominique Valeyre, Hilario Nunes, Zahir Amoura, Fleur Cohen Aubart
OBJECTIVE: To compare the efficacy of methotrexate (MTX) and mycophenolate mofetil (MMF) in the prevention of relapses in neurosarcoidosis. METHODS: We conducted a retrospective multicenter study including patients who received MTX or MMF for the treatment of histologically proven neurosarcoidosis. The efficacy of the immunosuppressive drug was assessed by determining the time to relapse. RESULTS: Forty patients with a diagnosis of neurosarcoidosis (24 men, 16 women, median age at diagnosis 43...
November 16, 2016: Neurology
https://www.readbyqxmd.com/read/27856387/robotic-versus-laparoscopic-staging-for-early-ovarian-cancer-a-case-matched-control-study
#8
V Gallotta, C Cicero, C Conte, G Vizzielli, M Petrillo, A Fagotti, V Chiantera, B Costantini, G Scambia, G Ferrandina
STUDY OBJECTIVE: This study aims to evaluate the feasibility, surgical outcome and oncological results observed after robotic staging compared to conventional laparoscopic staging for patients with early-stage ovarian cancer (EOC) patients. DESIGN: Retrospective cohort study (Canadian Task Force classification II-2). SETTING: Catholic University of the Sacred Hearth, Rome, Italy. PATIENTS: 96 patients underwent minimally invasive staging for presumed stage I ovarian cancer: 32 underwent robotic approach (Cases), and 64 underwent laparoscopic approach (Controls)...
November 14, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27845604/the-ambiguity-of-human-ashes-exploring-encounters-with-cremated-remains-in-the-netherlands
#9
Brenda Mathijssen
This paper explores cremation and disposal practices in the Netherlands, focusing on the attitudes and experiences of Dutch bereaved in relation to cremated remains. In academic and professional narratives human ashes are commonly described as 'important', as 'sacred', and as a vehicle to continue intense and physical relationships with the dead. Based on quantitative and qualitative data this paper illustrates the ambiguity of such relationships. It highlights the diverse experiences, unexpected challenges and moral obligations that can be evoked by the deceased's ashes, where the latter are seen as embedded in material practices and entangled in social relationships...
November 15, 2016: Death Studies
https://www.readbyqxmd.com/read/27833912/sacb-sacr-gene-cassette-as-the-negative-selection-marker-to-suppress-agrobacterium-overgrowth-in-agrobacterium-mediated-plant-transformation
#10
Yiming Liu, Jiamin Miao, Sy Traore, Danyu Kong, Yi Liu, Xunzhong Zhang, Zachary L Nimchuk, Zongrang Liu, Bingyu Zhao
Agrobacterium overgrowth is a common problem in Agrobacterium-mediated plant transformation. To suppress the Agrobacterium overgrowth, various antibiotics have been used during plant tissue culture steps. The antibiotics are expensive and may adversely affect plant cell differentiation and reduce plant transformation efficiency. The SacB-SacR proteins are toxic to most Agrobacterium tumefaciens strains when they are grown on culture medium supplemented with sucrose. Therefore, SacB-SacR genes can be used as negative selection markers to suppress the overgrowth of A...
2016: Frontiers in Molecular Biosciences
https://www.readbyqxmd.com/read/27833570/phenotypic-dimensions-of-spirituality-implications-for-mental-health-in-china-india-and-the-united-states
#11
Clayton H McClintock, Elsa Lau, Lisa Miller
While the field of empirical study on religion and spirituality in relation to mental health has rapidly expanded over the past decade, little is known about underlying dimensions of spirituality cross-culturally conceived. We aimed to bridge this gap by inductively deriving potential universal dimensions of spirituality through a large-scale, multi-national data collection, and examining the relationships of these dimensions with common psychiatric conditions. Five-thousand five-hundred and twelve participants from China, India, and the United States completed a two-hour online survey consisting of wide-ranging measures of the lived experience of spirituality, as well as clinical assessments...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27830941/-the-child-that-tiire-doesn-t-give-you-god-won-t-give-you-either-the-role-of-rotheca-myricoides-in-somali-fertility-practices
#12
Sada Mire
The paper introduces the Baanashada Dumarka, a Somali fertility therapy carried out by a spirit medium, known locally as 'Alaqad. Baanashada is aimed at women whose fertility issues are believed to be caused by spirits. The study also explores a component of the Baanashada, namely, the use of tiire (Rotheca myricoides), or the butterfly bush. Although Rotheca myricoides is known to possess a number of medicinal components as confirmed by studies of modern science, so far, there exist no studies on its potential (or lack of) fertility effects...
November 10, 2016: Anthropology & Medicine
https://www.readbyqxmd.com/read/27830753/lucky-rhythms-in-orbitofrontal-cortex-bias-gambling-decisions-in-humans
#13
Pierre Sacré, Matthew S D Kerr, Kevin Kahn, Jorge Gonzalez-Martinez, Juan Bulacio, Hyun-Joo Park, Matthew A Johnson, Susan Thompson, Jaes Jones, Vikram S Chib, John T Gale, Sridevi V Sarma
It is well established that emotions influence our decisions, yet the neural basis of this biasing effect is not well understood. Here we directly recorded local field potentials from the OrbitoFrontal Cortex (OFC) in five human subjects performing a financial decision-making task. We observed a striking increase in gamma-band (36-50 Hz) oscillatory activity that reflected subjects' decisions to make riskier choices. Additionally, these gamma rhythms were linked back to mismatched expectations or "luck" occurring in past trials...
November 10, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27822080/plant-wealth-of-a-sacred-grove-mallur-gutta-telangana-state-india
#14
Sateesh Suthari, Ramesh Kandagalta, Ajmeera Ragan, Vatsavaya S Raju
The Mallur Gutta (Hill) of Warangal district in Telangana state, India, reputed as a habitat for medicinal plants, was inventoried from 2009 to 2015 for its plant wealth through the traditional knowledge of the local people. The Hindu temples of Lord Sri Laxminarasimha Swamy and Lord Hanuman, and the ethnic worship of mahua trees indicated it was a sacred grove which was selected as a Medicinal Plants Conservation Area. The exploration of Mallur Gutta resulted in the enumeration and documentation of plant wealth representing 470 species of 318 genera pertaining to 95 families of vascular plants...
2016: International Journal of General Medicine
https://www.readbyqxmd.com/read/27812801/assessment-of-bacterial-community-composition-in-response-to-uranium-levels-in-sediment-samples-of-sacred-cauvery-river
#15
Jayaraman Suriya, Mootapally Chandra Shekar, Neelam Mustakali Nathani, Thangaiyan Suganya, Subramanian Bharathiraja, Muthukalingan Krishnan
Global industrialization is a major cause of effluent discharge from industries up to alarming concentrations. Especially, uranium concentrations in water bodies are of great concern, as its radioactivity significantly affects the persistent diversity of microbiota. Recently, continuous application of pesticides in the agricultural lands and accumulation of quartz that enter the Cauvery River has significantly increased the concentration of uranium (U) and other heavy metals. To perceive the impact of uranium on bacterial diversity in Cauvery River, sediment samples collected from polluted (UP) site with 32...
November 3, 2016: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/27795765/-surgical-management-of-sacroiliac-joint-lesions-in-unstable-pelvic-ring-fractures-using-percutaneous-iliosacral-screw-fixation
#16
Mohamed Amine Karabila, Ismail Hmouri, Tarik Madani, Younes Mhamdi, Mohamed Azouz, Mohamed Kharmaz, Mohamed Ouadaghiri, Moulay Omar Lamrani, Abdou Lahlou, Ahmed Bardouni, Mustapha Mahfoud, Mohamed Saleh Berrada, Christian Vasile
Pelvic fractures, usually are multiple, unstable fractures occuring most frequently due to violent traumatic events. Orthopedic treatment of these lesions is often distressing both to patients and medical personnel since it requires bed discharge or sometimes tractions which can have a duration up to 45 days and can compromise the static and the walking mechanisms; open operative management is difficult, carrying a significant burden in terms of morbidity and associated with vascular (venous plexus), nervous (sacred roots) or septic risk to take into account...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27768841/o6-2-deoxyguanosine-butylene-o6-2-deoxyguanosine-dna-interstrand-cross-links-are-replication-blocking-and-mutagenic-dna-lesions
#17
Wenyan Xu, Daniel Kool, Derek K O'Flaherty, Ashley Keating, Lauralicia Sacre, Martin Egli, Anne Marietta Noronha, Christopher James Wilds, Linlin Zhao
DNA interstrand cross-links (ICLs) are cytotoxic DNA lesions derived from reactions of DNA with a number of anti-cancer reagents as well as endogenous bifunctional electrophiles. Deciphering the DNA repair mechanisms of ICLs is important for understanding the toxicity of DNA cross-linking agents and for the development of effective chemotherapies. Previous research has focused on ICLs cross-linked with the N7 and N2 atoms of guanine as well as those formed at the N6 atom of adenine; however, little is known about the mutagenicity of O6-dG-derived ICLs...
October 21, 2016: Chemical Research in Toxicology
https://www.readbyqxmd.com/read/27763931/mantram-repetition-with-homeless-women-a-pilot-study
#18
Sally P Weinrich, Jill E Bormann, Dale Glaser, Sally Hardin, Mary Barger, Cabiria Lizarraga, Juan Del Rio, Carolyn B Allard
Women and families are the fastest growing segment of the homeless population. Negative attitudes of nurses toward homeless women are a major barrier to homeless women seeking health care. This cross-sectional, mixed-methods pilot study, conducted primarily by nurses, tested the Mantram Repetition Program for the first time with 29 homeless women. The Mantram Repetition Program is a spiritually based skills training that teaches mantram (sacred word) repetition as a cost-effective, personalized, portable, and focused strategy for reducing stress and improving well-being...
November 2016: Holistic Nursing Practice
https://www.readbyqxmd.com/read/27759717/the-sacred-cow-project-is-your-practice-udderly-out-of-date
#19
Doris Cavlovich
No abstract text is available yet for this article.
November 2016: Nursing
https://www.readbyqxmd.com/read/27744374/the-tribal-tobacco-education-and-policy-initiative-findings-from-a-collaborative-participatory-evaluation
#20
Sheryl Scott, Joanne D'Silva, Carol Hernandez, Nicole Toves Villaluz, Jaime Martinez, Chris Matter
While the reduction in the overall U.S. smoking prevalence has been declared one of the top 10 public health achievements of the past century, the growing disparity in smoking between American Indians and the general population is one of the biggest challenges of the 21st century. Minnesota in particular has very high smoking rates among American Indians (59%). Tribal Nations in Minnesota share a past of attempted cultural genocide and a present of restoring the strength of their cultural teachings, including the prominence of traditional tobacco as a sacred "first medicine...
October 14, 2016: Health Promotion Practice
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