keyword
MENU ▼
Read by QxMD icon Read
search

Joel

keyword
https://www.readbyqxmd.com/read/28214570/routine-urethrograpy-after-buccal-graft-bulbar-urethroplasty-the-impact-of-initial-urethral-leak-on-surgical-success
#1
Erik T Grossgold, Jairam R Eswara, Cary L Siegel, Joel Vetter, Steven B Brandes
OBJECTIVE: To determine the long-term impact of extravasation at initial post-urethroplasty urethrogram, we present a novel classification system and report the association of leak severity with outcome. MATERIALS AND METHODS: 91 patients underwent buccal graft urethroplasties of the bulbar urethra from 2007-2015. Median time to urethrogram was 23d. All leaks were characterized by length and width. Cutoffs for length and width were calculated using ROC curves. Each urethrogram was graded 0-3 (0=no leak) with one point given for any leak, length ≥1...
February 15, 2017: Urology
https://www.readbyqxmd.com/read/28214070/microbiote-intestinal%C3%A2-qu%C3%A2-en-attendre-au-plan-physiologique-et-th%C3%A3-rapeutique%C3%A2
#2
Joël Doré, Marie-Christine Multon, Jehan-Michel Béhier, Hervé Affagard, Antoine Andremont, Philippe Barthélémy, Rui Batista, Marc Bonneville, Christophe Bonny, Gwendoline Boyaval, Mathias Chamaillard, Marie-Pierre Chevalier, Magali Cordaillat-Simmons, Fabienne Cournarie, Isabelle Diaz, Elisabeth Guillaume, Cyril Guyard, Evelyne Jouvin-Marche, François-Pierre Martin, David Petiteau
No abstract text is available yet for this article.
January 11, 2017: Thérapie
https://www.readbyqxmd.com/read/28213923/diagnostic-accuracy-of-charcot-s-triad-a-systematic-review
#3
REVIEW
Steva Rumsey, Joel Winders, Andrew D MacCormick
BACKGROUND: Charcot's triad is a well-established diagnostic tool for acute cholangitis (AC). It has been recognized as an inaccurate test in clinical practice; however, its exact sensitivity and specificity remain unclear. This knowledge is key to informing the value of its continued clinical application. The objectives of this study are to calculate an estimate of the sensitivity and specificity of Charcot's triad based on published research and consider its applicability to clinical practice and medical education...
February 17, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28213566/a-randomised-phase-iib-study-of-mavrilimumab-a-novel-gm-csf-receptor-alpha-monoclonal-antibody-in-the-treatment-of-rheumatoid-arthritis
#4
Gerd R Burmester, Iain B McInnes, Joel Kremer, Pedro Miranda, Mariusz Korkosz, Jiri Vencovsky, Andrea Rubbert-Roth, Eduardo Mysler, Matthew A Sleeman, Alex Godwood, Dominic Sinibaldi, Xiang Guo, Wendy I White, Bing Wang, Chi-Yuan Wu, Patricia C Ryan, David Close, Michael E Weinblatt
OBJECTIVES: Despite the therapeutic value of current rheumatoid arthritis (RA) treatments, agents with alternative modes of action are required. Mavrilimumab, a fully human monoclonal antibody targeting the granulocyte-macrophage colony-stimulating factor receptor-α, was evaluated in patients with moderate-to-severe RA. METHODS: In a phase IIb study (NCT01706926), patients with inadequate response to ≥1 synthetic disease-modifying antirheumatic drug(s), Disease Activity Score 28 (DAS28)-C reactive protein (CRP)/erythrocyte sedimentation rate ≥3...
February 17, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28213437/%C3%AE-synuclein-multiple-system-atrophy-prions
#5
Amanda L Woerman, Joel C Watts, Atsushi Aoyagi, Kurt Giles, Lefkos T Middleton, Stanley B Prusiner
Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disease arising from the misfolding and accumulation of the protein α-synuclein in oligodendrocytes, where it forms glial cytoplasmic inclusions (GCIs). Several years of studying synthetic α-synuclein fibrils has provided critical insight into the ability of α-synuclein to template endogenous protein misfolding, giving rise to fibrillar structures capable of propagating from cell to cell. However, more recent studies with MSA-derived α-synuclein aggregates have shown that they have a similar ability to undergo template-directed propagation, like PrP prions...
February 17, 2017: Cold Spring Harbor Perspectives in Medicine
https://www.readbyqxmd.com/read/28213382/pharmacist-involvement-on-a-rapid-response-team
#6
Joel Feih, William J Peppard, Michael Katz
PURPOSE: The effect of a pharmacist on a rapid response team (RRT) was investigated. METHODS: This study evaluated 234 patients before and 157 patients after pharmacist involvement on an RRT. The primary outcome was time to medication administration, with a goal turnaround time of less than 30 minutes. Secondary outcomes included most frequently used medications, readmissions to the intensive care unit (ICU) within 48 hours, number of rapid responses that resulted in ICU admission, length of hospital stay, and survival to hospital discharge...
March 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28213046/splenectomy-as-a-destination-improving-quality-of-care-among-asplenic-veterans-through-a-travel-clinic
#7
Aaron P Mitchell, Joel C Boggan, Karen Lau, David L Simel
BACKGROUND: Asplenic patients are at risk for severe infections, but adherence to recommended preventive education and vaccination is poor. The goal of this study was to demonstrate that a targeted intervention can improve vaccination rates in a population of asplenic veterans. METHODS: Surgically asplenic patients actively receiving care in our health care system were identified via a database search. Patients were contacted via mailed letters and encouraged to attend an existing travel clinic with a new process designed for asplenic patients...
February 14, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28212760/psoriasis-and-comorbid-diseases-implications-for-management
#8
REVIEW
Junko Takeshita, Sungat Grewal, Sinéad M Langan, Nehal N Mehta, Alexis Ogdie, Abby S Van Voorhees, Joel M Gelfand
As summarized in the first article in this continuing medical education series, the currently available epidemiologic data suggest that psoriasis may be a risk factor for cardiometabolic disease. Emerging data also suggest associations between psoriasis and other comorbidities beyond psoriatic arthritis, including chronic kidney disease, inflammatory bowel disease, hepatic disease, certain malignancies, infections, and mood disorders. Recognizing the comorbid disease burden of psoriasis is essential for ensuring comprehensive care of patients with psoriasis...
March 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28212759/psoriasis-and-comorbid-diseases-epidemiology
#9
REVIEW
Junko Takeshita, Sungat Grewal, Sinéad M Langan, Nehal N Mehta, Alexis Ogdie, Abby S Van Voorhees, Joel M Gelfand
Psoriasis is a common chronic inflammatory disease of the skin that is increasingly being recognized as a systemic inflammatory disorder. Psoriatic arthritis is a well-known comorbidity of psoriasis. A rapidly expanding body of literature in various populations and settings supports additional associations between psoriasis and cardiometabolic diseases, gastrointestinal diseases, kidney disease, malignancy, infection, and mood disorders. The pathogenesis of comorbid disease in patients with psoriasis remains unknown; however, shared inflammatory pathways, cellular mediators, genetic susceptibility, and common risk factors are hypothesized to be contributing elements...
March 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28212643/vertical-hiv-transmission-in-perinatally-exposed-infants-in-south-rift-region-of-kenya-a-retrospective-cross-sectional-study
#10
Everline Ashiono, Dunstan Achwoka, Jamlick Mutugi, Joel Rakwar, Andrew Wafula, Otto Nzapfurundi Chabikuli
BACKGROUND: Despite proven efficacy of the prevention mother-to-child transmission of HIV strategy, its adoption in Africa has remained slow. In Kenya, its effectiveness remain unknown. The aim of this study was to assess the effectiveness of a prevention of mother-to-child transmission program in Kenya. METHODS: This retrospective cross-sectional study analyzed 2,642 records of HIV-exposed infants who had a deoxyribonucleic acid polymerase chain reaction test done...
February 17, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28212035/ultrafast-time-resolved-x-ray-absorption-spectroscopy-of-ferrioxalate-photolysis-with-a-laser-plasma-x-ray-source-and-microcalorimeter-array
#11
Galen C O'Neil, Luis Miaja-Avila, Young Il Joe, Bradley K Alpert, Mahalingam Balasubramanian, Dodderi M Sagar, William Bertrand Doriese, Joseph W Fowler, Wilfred K Fullagar, Ning Chen, Gene C Hilton, Ralph Jimenez, Bruce Ravel, Carl D Reintsema, Dan R Schmidt, Kevin L Silverman, Daniel S Swetz, Jens Uhlig, Joel N Ullom
The detailed pathways of photoactivity on ultrafast timescales are a topic of contemporary interest. Using a tabletop apparatus based upon a laser plasma x-ray source and an array of cryogenic microcalorimeter x-ray detectors, we have measured a transient x-ray absorption spectrum during the ferrioxalate photoreduction reaction. With these high efficiency detectors we observe the Fe K edge move to lower energies, and the amplitude of the extended x-ray absorption fine structure reduce, consistent with a photoreduction mechanism in which electron transfer precedes disassociation...
February 17, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28211994/building-the-coverage-continuum-the-role-of-state-medicaid-directors-and-insurance-commissioners
#12
Joel Ario, Deborah Bachrach
Issue: The Affordable Care Act has expanded coverage to 20 million newly insured individuals, split between state Medicaid programs and commercially insured marketplaces, with limited integration between the two. The seamless continuum of coverage envisioned by the law is central to achieving the full potential of the Affordable Care Act, but it remains an elusive promise. Goals: To examine the historical and cultural differences between state Medicaid agencies and insurance departments that contribute to this lack of coordination...
2017: Issue Brief of the Commonwealth Fund
https://www.readbyqxmd.com/read/28211096/monocyte-and-lymphocyte-surface-molecules-in-severe-sepsis-and-non-septic-critically-ill-patients
#13
Joel Jämsä, Hannu Syrjälä, Virva Huotari, Eeva-Riitta Savolainen, Tero Ala-Kokko
The aim of the present study was to investigate whether expression of monocyte and lymphocyte surface molecules differs between patients with severe sepsis and non-septic patients treated in the intensive care unit (ICU). The expression of monocyte CD14, CD40, CD80 and HLA-DR, and lymphocyte CD69 were analyzed using quantitative flow cytometry on three consecutive days in 27 patients with severe sepsis and in 15 non-septic patients. Receiver operating characteristic analyses were performed and each corresponding area under the curve (AUC) was determined...
February 17, 2017: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/28210767/crohn-s-disease-diagnosis-treatment-approach-and-management-paradigm-what-the-radiologist-needs-to-know
#14
Parakkal Deepak, Sang Hyoung Park, Eric C Ehman, Stephanie L Hansel, Jeff L Fidler, David H Bruining, Joel G Fletcher
Crohn's disease is one of the major subtypes of idiopathic inflammatory bowel disease and is characterized by chronic transmural intestinal inflammation of the gastrointestinal tract anywhere from mouth to the anus, with a predilection for the small bowel. Cross-sectional imaging with computed tomography and magnetic resonance enterography plays a key role in confirming diagnosis, identifying and managing complications, assessing disease severity, and identifying response to medical therapy. This review will focus on the role of radiologists in the diagnosis and assessment of Crohn's disease...
February 16, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28210540/an-aggressive-non-small-cell-lung-cancer-in-nonsmokers-a-case-report-of-an-unusual-presentation-of-micropapillary-lung-adenocarcinoma
#15
Aixa Dones Rodríguez, Kelvin Rivera Manzano, Ricardo Fernández González, José R Adorno Fontánez, Ricardo A Hernández, Modesto Gonález Del Rosario, Rafael Vicens Rodríguez, Joel E Nieves Scharon
We describe a case of an unusual fast growing lung micropapillary-predominant adenocarcinoma in a nonsmoker male patient without pre-existing lung disease. Adenocarcinomas have been described to be slow growing tumors, however our patient presented a fast-growing rate over a period of 21 days. When the patient failed broad spectrum antibiotic coverage, malignancy became part of the differential diagnosis. Once malignancy was detected, prompt identification and treatment was started in order to improve prognosis of the patients...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28210536/race-and-place-differences-in-patients-hospitalized-with-an-acute-coronary-syndrome-is-there-double-jeopardy-findings-from-trace-core
#16
Robert J Goldberg, Joel M Gore, David D McManus, Richard McManus, Mayra Tisminetzky, Darleen Lessard, Jerry H Gurwitz, David C Parish, Jeroan Allison, Connie Ng Hess, Tracy Wang, Catarina Kiefe
The objectives of this longitudinal study were to examine differences between whites and blacks, and across two geographical regions, in the socio-demographic, clinical, and psychosocial characteristics, hospital treatment practices, and post-discharge mortality for hospital survivors of an acute coronary syndrome (ACS). In this prospective cohort study, we performed in-person interviews and medical record abstractions for patients discharged from the hospital after an ACS at participating sites in Central Massachusetts and Central Georgia during 2011-2013...
June 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28209992/from-basic-apoptosis-discoveries-to-advanced-selective-bcl-2-family-inhibitors
#17
REVIEW
Avi Ashkenazi, Wayne J Fairbrother, Joel D Leverson, Andrew J Souers
Members of the B cell lymphoma 2 (BCL-2) gene family have a central role in regulating programmed cell death by controlling pro-apoptotic and anti-apoptotic intracellular signals. In cancer, apoptosis evasion through dysregulation of specific BCL-2 family genes is a recurring event; accordingly, selective inhibition of specific anti-apoptotic BCL-2 family proteins represents an exciting therapeutic opportunity. A combination of nuclear magnetic resonance (NMR)-based screening and structure-based drug design has yielded the first bona fide BCL-2 homology 3 (BH3) mimetics, including the BCL-2 and BCL-XL dual antagonist navitoclax, which is the first BCL-2 family inhibitor to show efficacy in patients with cancer...
February 17, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28209759/revisiting-seed-and-soil-examining-the-primary-tumor-and-cancer-cell-foraging-in-metastasis
#18
Amber E de Groot, Sounak Roy, Joel S Brown, Kenneth J Pienta, Sarah R Amend
Metastasis is the consequence of a cancer cell that disperses from the primary tumor, travels throughout the body, and invades and colonizes a distant site.  Based on Paget's 1889 hypothesis, the majority of modern metastasis research focuses on the properties of the metastatic "seed and soil," but the implications of the primary tumor "soil" have been largely neglected. The rare lethal metastatic "seed" arises as a result of the selective pressures in the primary tumor. Optimal foraging theory describes how cancer cells adopt a mobile foraging strategy to balance predation risk and resource reward...
February 16, 2017: Molecular Cancer Research: MCR
https://www.readbyqxmd.com/read/28208210/heterogeneous-costs-of-alcohol-and-drug-problems-across-cities-and-counties-in-california
#19
Ted R Miller, Peter Nygaard, Andrew Gaidus, Joel W Grube, William R Ponicki, Bruce A Lawrence, Paul J Gruenewald
BACKGROUND: Estimates of economic and social costs related to alcohol and other drug (AOD) use and abuse are usually made at state and national levels. Ecological analyses demonstrate, however, that substantial variations exist in the incidence and prevalence of AOD use and problems including impaired driving, violence, and chronic disease between smaller geopolitical units like counties and cities. This study examines the ranges of these costs across counties and cities in California...
February 16, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28208122/a-conversation-among-the-ias-usa-board-of-directors-hot-topics-and-emerging-data-in-hiv-research-and-care
#20
Constance A Benson, Judith S Currier, Carlos Del Rio, Joel E Gallant, Roy M Gulick, Jeanne M Marrazzo, Douglas D Richman, Michael S Saag, Robert T Schooley, Paul A Volberding
The IAS-USA volunteer Board of Directors met in October 2016 for its annual meeting. For the second year, the Board conducted a live, hour-long, interactive, roundtable webinar covering current questions and issues in HIV research, prevention, and care. Important highlights from the Board's discussion, which was moderated by Paul A. Volberding, MD, are included below. Members of the IAS-USA volunteer Board of Directors are Constance A. Benson, MD; Judith S. Currier, MD; Carlos del Rio, MD; Joel E. Gallant, MD, MPH; Roy M...
December 2017: Topics in Antiviral Medicine
keyword
keyword
61530
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"