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https://www.readbyqxmd.com/read/28431772/low-glycemic-index-treatment-in-patients-with-drug-resistant-epilepsy
#1
Se Hee Kim, Hoon-Chul Kang, Eun Joo Lee, Joon Soo Lee, Heung Dong Kim
OBJECTIVE: Low glycemic index treatment (LGIT) is a newly developed dietary therapeutic option for epilepsy that is less restrictive than the ketogenic diet (KD). Our objective was to determine the efficacy and tolerability of LGIT. METHODS: From March 2014 to February 2015, 36 patients received LGIT at Severance Children's Hospital. One-year seizure outcomes and side effects were evaluated. RESULTS: A total of 36 patients were assessed. Fourteen were female...
April 18, 2017: Brain & Development
https://www.readbyqxmd.com/read/28430796/prevalence-and-associated-factors-of-tuberculosis-and-diabetes-mellitus-comorbidity-a-systematic-review
#2
Mahteme Haile Workneh, Gunnar Aksel Bjune, Solomon Abebe Yimer
INTRODUCTION: The dual burden of tuberculosis (TB) and diabetes mellitus (DM) has become a major global public health concern. There is mounting evidence from different countries on the burden of TB and DM comorbidity. The objective of this systematic review was to summarize the existing evidence on prevalence and associated/risk factors of TBDM comorbidity at global and regional levels. METHODS: Ovid Medline, Embase, Global health, Cochrane library, Web of science and Scopus Elsevier databases were searched to identify eligible articles for the systematic review...
2017: PloS One
https://www.readbyqxmd.com/read/28429581/nighttime-is-the-worst-time-parental-fear-of-hypoglycemia-in-young-children-with-type-1-diabetes
#3
Michelle A Van Name, Marisa E Hilliard, Claire T Boyle, Kellee M Miller, Daniel J DeSalvo, Barbara J Anderson, Lori M Laffel, Stephanie E Woerner, Linda A DiMeglio, William V Tamborlane
BACKGROUND: Fear of hypoglycemia is common in parents of young children with type 1 diabetes (T1D), but little is known about the specific fears that parents most often experience. Hypoglycemia fear has been associated with poorer glycemic control in older children, though not yet studied in a large cohort of very young children. MATERIALS AND METHODS: Parents of 549 children <7 years (mean 5.2 ± 1.2 years [19% <3 years]) with a mean diabetes duration of 2...
April 21, 2017: Pediatric Diabetes
https://www.readbyqxmd.com/read/28422059/mismatch-between-probiotic-benefits-in-trials-versus-food-products
#4
Mary J Scourboutakos, Beatriz Franco-Arellano, Sarah A Murphy, Sheida Norsen, Elena M Comelli, Mary R L'Abbé
Probiotic food products contain a variety of different bacterial strains and may offer different health effects. The objective was to document the prevalence and dosage of probiotic strains in the Canadian food supply and to review the literature investigating these strains in order to understand what health benefits these products may offer. The Food Label Information Program was used to identify probiotic-containing products in the food supply. PubMed, Web of Science, and Embase were searched for randomized controlled trials that tested the health effects of these strains in humans...
April 19, 2017: Nutrients
https://www.readbyqxmd.com/read/28420583/diabetes-medication-persistence-different-medications-have-different-persistence-rates
#5
Michal Shani, Alex Lustman, Shlomo Vinker
AIM: To assess the persistence of diabetic patients to oral medications. METHODS: The study included all type 2 diabetic patients over 40 years, members of one District of Clalit Health Services Israel, who were diagnosed with diabetes mellitus before 2008 and who filled at least one prescription per year during 2008-2010, for the following medications: metformin, glibenclamide, acarbose, statins, angiotensin converting enzyme inhibitors (ACEI) and angiotensin II receptor antagonists (ARBs)...
April 15, 2017: Primary Care Diabetes
https://www.readbyqxmd.com/read/28417910/effects-of-three-commercially-available-sports-drinks-on-substrate-metabolism-and-subsequent-endurance-performance-in-a-postprandial-state
#6
Lu Qin, Qi-Rong Wang, Zi-Long Fang, Ting Wang, Ai-Qi Yu, Yu-Jie Zhou, Yi Zheng, Mu-Qing Yi
Purpose: To examine the effects of commercially available sports beverages with various components on substrate metabolism and subsequent performance. Methods: Two studies were conducted in a double-blinded, counterbalanced manner. Study I was designed to determine the glycemic index, while study II determined the utilization of substrates and subsequent exercise performance. Ten healthy male participants (age 21.70 ± 2.41 years, height 176.60 ± 5.23 cm, weight 66.58 ± 5.38 kg, V̇O2max 48.1 ± 8.4 mL/kg/min) participated in both study I and study II...
April 12, 2017: Nutrients
https://www.readbyqxmd.com/read/28417532/non-alcoholic-fatty-liver-disease-nafld-prevalence-and-its-metabolic-associations-in-patients-with-type-1-diabetes-and-type-2-diabetes
#7
Kenneth Cusi, Arun J Sanyal, Shuyu Zhang, Mark L Hartman, Juliana M Bue-Valleskey, Byron J Hoogwerf, Axel Haupt
We investigated non-alcoholic fatty liver disease (NAFLD) prevalence and its metabolic associations in patients with type 1 diabetes (T1D), and in insulin-naïve and insulin-treated patients with type 2 diabetes (T2D). Baseline data from patients who had liver fat content (LFC) evaluated by magnetic resonance imaging in 4 phase 3 studies of basal insulin peglispro (BIL) were analyzed. Associations of NAFLD with clinical characteristics, glycemic control and diabetes therapy were evaluated. The prevalence of NAFLD (defined as LFC ≥6%) was low in T1D (8...
April 17, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28417082/improving-glucose-tolerance-by-muscle-damaging-exercise
#8
Chien-Te Ho, Machiko Otaka, Chia-Hua Kuo
Tissue damage is regarded as an unwanted medical condition to be avoided. However, introducing tolerable tissue damages has been used as a therapeutic intervention in traditional and complementary medicine to cure discomfort and illness. Eccentric exercise is known to cause significant necrosis and insulin resistance of skeletal muscle. The purpose of this study was to determine the magnitude of muscle damage and blood glucose responses during an oral glucose tolerance test (OGTT) after eccentric training in 21 young participants...
April 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/28416531/treatment-deintensification-is-uncommon-in-adults-with-type-2-diabetes-mellitus-a-retrospective-cohort-study
#9
Finlay A McAlister, Erik Youngson, Dean T Eurich
BACKGROUND: Whether treatment deintensification in Americans with diabetes mellitus varies by glycemic control, health status, and calendar year (before/after February 2008 when safety concerns about intensive glucose control were reported in the ACCORD trial [Action to Control Cardiovascular Risk in Diabetes]) is unclear. METHODS AND RESULTS: We defined deintensification as discontinuation or dosage decrease of at least 1 glycemic medication without addition of, or uptitration of, another agent in the 120 days after the index glycosylated hemoglobin (HbA1C) measurement...
April 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28416368/nutritional-management-in-women-with-polycystic-ovary-syndrome-a-review-study
#10
REVIEW
Zeinab Faghfoori, Siavash Fazelian, Mahdi Shadnoush, Reza Goodarzi
Polycystic ovary syndrome (PCOS) is endocrine disorder in women of reproductive age, which leads to reproductive, hormonal and metabolic abnormalities. Due to the presence of insulin resistance, PCOS increases the risk of chronic diseases like type 2 diabetes, hypertension, lipid disorders, cardiovascular diseases and malignancies such as breast and endometrial cancer. The actual cause of this syndrome is unknown but environmental factors such as dietary habits play an important role in prevention and treatment and lifestyle modifications are the most important therapeutic strategies in these patients...
April 5, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28413419/role-of-vitamin-d-on-glycemic-control-and-oxidative-stress-in-type-2-diabetes-mellitus
#11
Mostafa Saif-Elnasr, Iman M Ibrahim, Manal M Alkady
BACKGROUND: Vitamin D deficiency may play a key role in the development of impaired glucose tolerance, type 2 diabetes mellitus (T2DM), and metabolic syndrome. Several studies have shown that Vitamin D has an antioxidant property. We aimed to investigate 25-hydroxy Vitamin D (25[OH]D) levels in patients with T2DM and in nondiabetic healthy controls and to ascertain the impact of 25(OH)D levels on glycemic control and oxidative stress in T2DM patients. MATERIALS AND METHODS: Thirty male patients with T2DM and twenty age- and socioeconomic status-matched male healthy controls were included in the study...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28409320/vitamin-d-sub-inflammation-and-insulin-resistance-a-window-on-a-potential-role-for-the-interaction-between-bone-and-glucose-metabolism
#12
REVIEW
Stefania Giuliana Garbossa, Franco Folli
Vitamin D is a key hormone involved in the regulation of calcium/phosphorous balance and recently it has been implicated in the pathogenesis of sub-inflammation, insulin resistance and obesity. The two main forms of vitamin D are cholecalciferol (Vitamin D3) and ergocalciferol (Vitamin D2): the active form (1,25-dihydroxyvitamin D) is the result of two hydroxylations that take place in liver, kidney, pancreas and immune cells. Vitamin D increases the production of some anti-inflammatory cytokines and reduces the release of some pro-inflammatory cytokines...
April 13, 2017: Reviews in Endocrine & Metabolic Disorders
https://www.readbyqxmd.com/read/28406437/low-glycemic-index-prototype-isomaltulose-update-of-clinical-trials
#13
REVIEW
Constanze Christin Maresch, Sebastian Friedrich Petry, Stephan Theis, Anja Bosy-Westphal, Thomas Linn
Low glycemic index diets are supposed to achieve a more beneficial effect on blood glucose control in people with diabetes mellitus and may also provide metabolic benefits for the general population. A prototype of a low-glycemic index carbohydrate is the natural occurring disaccharide isomaltulose that can be commercially produced from sucrose (beet sugar) to industrial scale. It is currently used in various food and drink applications as well as special and clinical nutrition feeds and formula diet as a food ingredient and alternative sugar...
April 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28405346/safety-and-efficacy-of-saxagliptin-for-glycemic-control-in-non-critically-ill-hospitalized-patients
#14
Rajesh Garg, Brooke Schuman, Shelley Hurwitz, Cheyenne Metzger, Shreya Bhandari
OBJECTIVE: To evaluate whether saxagliptin is non-inferior to basal-bolus insulin therapy for glycemic control in patients with controlled type 2 diabetes mellitus (T2DM) admitted to hospital with non-critical illnesses. RESEARCH DESIGN AND METHODS: This was an open-label, randomized controlled clinical trial. Patients received either saxagliptin or basal-bolus insulin, both with correctional insulin doses. The main study outcome was the mean daily blood glucose (BG) after the first day of randomization...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28405345/lower-glycemic-load-meals-reduce-diurnal-glycemic-oscillations-in-women-with-risk-factors-for-gestational-diabetes
#15
Nathalie V Kizirian, Janina Goletzke, Shannon Brodie, Fiona S Atkinson, Tania P Markovic, Glynis P Ross, Anette Buyken, Jennie P Brand-Miller
OBJECTIVE: Maternal glycemia plays a key role in fetal growth. We hypothesized that lower glycemic load (GL) meals (lower glycemic index, modestly lower carbohydrate) would substantially reduce day-long glucose variability in women at risk of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS: A crossover study of 17 women (mean±SD age 34.8±4 years; gestational weeks 29.3±1.3; body mass index 23.8±4.7 kg/m(2)) who consumed a low GL or a high GL diet in random order, 1-day each, over 2 consecutive days...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28405340/association-of-physiological-and-psychological-health-outcomes-with-physical-activity-and-sedentary-behavior-in-adults-with-type-2-diabetes
#16
Jeanette M Garcia, Daniel Cox, David J Rice
PURPOSE: To examine the association between change in moderate-to-vigorous physical activity (MVPA) and sedentary behavior (SB) over a 6-month period with physiological and psychological factors in adults with type 2 diabetes (T2D). METHODS: Participants included 26 middle-aged (mean age=56.1±10.8 years; 42% women), overweight/obese (mean body mass index (BMI) =37.22±8.78 kg/m(2)) adults who had been diagnosed with T2D within the past 5 years (mean HbA1c=7...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28404659/early-glycemic-control-and-magnitude-of-hba1c-reduction-predict-cardiovascular-events-and-mortality-population-based-cohort-study-of-24-752-metformin-initiators
#17
Elisabeth Svensson, Lisbeth M Baggesen, Søren P Johnsen, Lars Pedersen, Helene Nørrelund, Esben S Buhl, Christiane L Haase, Reimar W Thomsen
OBJECTIVE: We investigated the association of early achieved HbA1c level and magnitude of HbA1c reduction with subsequent risk of cardiovascular events or death in patients with type 2 diabetes who initiate metformin. RESEARCH DESIGN AND METHODS: This was a population-based cohort study including all metformin initiators with HbA1c tests in Northern Denmark, 2000-2012. Six months after metformin initiation, we classified patients by HbA1c achieved (<6.5% or higher) and by magnitude of HbA1c change from the pretreatment baseline...
April 12, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28404579/glycemic-index-glycemic-load-and-blood-pressure-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#18
Charlotte El Evans, Darren C Greenwood, Diane E Threapleton, Chris P Gale, Christine L Cleghorn, Victoria J Burley
Background: High blood pressure is a strong risk factor for cardiovascular disease.Objective: The aim of this study was to determine the associations of dietary glycemic index (GI) and glycemic load (GL) with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in healthy individuals.Design: A systematic review and meta-analysis of randomized controlled trials (RCTs) was carried out. Databases were searched for eligible RCTs in 2 phases. MEDLINE, Embase, CAB Abstracts, BIOSIS, ISI Web of Science, and the Cochrane Library were searched from January 1990 to December 2009...
April 12, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28399076/effects-of-a-10-day-intensive-health-promotion-program-combining-diet-and-physical-activity-on-body-composition-physical-fitness-and-blood-factors-of-young-adults-a-randomized-pilot-study
#19
Kyoung Soon Lee, Jae Koo Lee, Young Ran Yeun
BACKGROUND A lifestyle characterized by poor eating habits and physical inactivity is a risk factor for multiple lifestyle diseases in young adults. This study assessed the effects of implementing an intensive 10-day health promotion program combining diet and physical activities on body composition, physical fitness, and biochemical parameters of young adults. MATERIAL AND METHODS In this randomized pilot study, 30 female undergraduate students were randomly allocated to an intervention and a control group...
April 11, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28392166/legume-consumption-is-inversely-associated-with-type-2-diabetes-incidence-in-adults-a-prospective-assessment-from-the-predimed-study
#20
Nerea Becerra-Tomás, Andrés Díaz-López, Núria Rosique-Esteban, Emilio Ros, Pilar Buil-Cosiales, Dolores Corella, Ramon Estruch, Montserrat Fitó, Lluís Serra-Majem, Fernando Arós, Rosa Maria Lamuela-Raventós, Miquel Fiol, José Manuel Santos-Lozano, Javier Díez-Espino, Olga Portoles, Jordi Salas-Salvadó
BACKGROUND & AIMS: Legumes, a low-energy, nutrient-dense and low glycemic index food, have shown beneficial effects on glycemic control and adiposity. As such, legumes are widely recommended in diabetic diets, even though there is little evidence that their consumption protects against type 2 diabetes. Therefore the aim of the present study was to examine the associations between consumption of total legumes and specific subtypes, and type 2 diabetes risk. We also investigated the effect of theoretically substituting legumes for other protein- or carbohydrate-rich foods...
March 24, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
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